GO:0000001	mitochondrion inheritance	biological_process	The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.
GO:0000002	mitochondrial genome maintenance	biological_process	The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
GO:0000003	reproduction	biological_process	The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
GO:0000006	high-affinity zinc transmembrane transporter activity	molecular_function	Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0000007	low-affinity zinc ion transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0000009	alpha-1,6-mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
GO:0000010	trans-hexaprenyltranstransferase activity	molecular_function	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.
GO:0000011	vacuole inheritance	biological_process	The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
GO:0000012	single strand break repair	biological_process	The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
GO:0000015	phosphopyruvate hydratase complex	cellular_component	A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
GO:0000016	lactase activity	molecular_function	Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
GO:0000017	alpha-glucoside transport	biological_process	The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.
GO:0000018	regulation of DNA recombination	biological_process	Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
GO:0000019	regulation of mitotic recombination	biological_process	Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.
GO:0000022	mitotic spindle elongation	biological_process	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
GO:0000023	maltose metabolic process	biological_process	The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.
GO:0000024	maltose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
GO:0000025	maltose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
GO:0000026	alpha-1,2-mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
GO:0000027	ribosomal large subunit assembly	biological_process	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
GO:0000028	ribosomal small subunit assembly	biological_process	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
GO:0000030	mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0000031	mannosylphosphate transferase activity	molecular_function	Catalysis of the transfer of a mannosylphosphate group from one compound to another.
GO:0000032	cell wall mannoprotein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
GO:0000033	alpha-1,3-mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.
GO:0000034	adenine deaminase activity	molecular_function	Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
GO:0000035	acyl binding	molecular_function	Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
GO:0000036	acyl carrier activity	molecular_function	Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.
GO:0000038	very long-chain fatty acid metabolic process	biological_process	The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
GO:0000041	transition metal ion transport	biological_process	The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
GO:0000045	autophagosome assembly	biological_process	The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
GO:0000048	peptidyltransferase activity	molecular_function	Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme.
GO:0000049	tRNA binding	molecular_function	Binding to a transfer RNA.
GO:0000050	urea cycle	biological_process	The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.
GO:0000052	citrulline metabolic process	biological_process	The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
GO:0000053	argininosuccinate metabolic process	biological_process	The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.
GO:0000054	ribosomal subunit export from nucleus	biological_process	The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
GO:0000055	ribosomal large subunit export from nucleus	biological_process	The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.
GO:0000056	ribosomal small subunit export from nucleus	biological_process	The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.
GO:0000062	fatty-acyl-CoA binding	molecular_function	Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
GO:0000064	L-ornithine transmembrane transporter activity	molecular_function	Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.
GO:0000070	mitotic sister chromatid segregation	biological_process	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
GO:0000073	initial mitotic spindle pole body separation	biological_process	The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB.
GO:0000075	cell cycle checkpoint signaling	biological_process	A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
GO:0000076	DNA replication checkpoint signaling	biological_process	A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
GO:0000077	DNA damage checkpoint signaling	biological_process	A signal transduction process that contributes to a DNA damage checkpoint.
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	biological_process	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
GO:0000080	mitotic G1 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
GO:0000082	G1/S transition of mitotic cell cycle	biological_process	The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	biological_process	Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
GO:0000084	mitotic S phase	biological_process	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
GO:0000085	mitotic G2 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
GO:0000086	G2/M transition of mitotic cell cycle	biological_process	The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
GO:0000087	mitotic M phase	biological_process	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
GO:0000088	mitotic prophase	biological_process	The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GO:0000089	mitotic metaphase	biological_process	The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.
GO:0000090	mitotic anaphase	biological_process	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.
GO:0000091	mitotic anaphase A	biological_process	The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.
GO:0000092	mitotic anaphase B	biological_process	The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.
GO:0000093	mitotic telophase	biological_process	The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GO:0000095	S-adenosyl-L-methionine transmembrane transporter activity	molecular_function	Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
GO:0000096	sulfur amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.
GO:0000097	sulfur amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
GO:0000098	sulfur amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
GO:0000099	sulfur amino acid transmembrane transporter activity	molecular_function	Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.
GO:0000100	S-methylmethionine transmembrane transporter activity	molecular_function	Enables the transfer of S-methylmethionine from one side of a membrane to the other.
GO:0000101	sulfur amino acid transport	biological_process	The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0000102	L-methionine secondary active transmembrane transporter activity	molecular_function	Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0000103	sulfate assimilation	biological_process	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
GO:0000104	succinate dehydrogenase activity	molecular_function	Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
GO:0000105	histidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0000107	imidazoleglycerol-phosphate synthase activity	molecular_function	Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+.
GO:0000109	nucleotide-excision repair complex	cellular_component	Any complex formed of proteins that act in nucleotide-excision repair.
GO:0000110	nucleotide-excision repair factor 1 complex	cellular_component	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.
GO:0000111	nucleotide-excision repair factor 2 complex	cellular_component	One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.
GO:0000112	nucleotide-excision repair factor 3 complex	cellular_component	One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).
GO:0000113	nucleotide-excision repair factor 4 complex	cellular_component	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.
GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle	biological_process	Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle.
GO:0000118	histone deacetylase complex	cellular_component	A protein complex that possesses histone deacetylase activity.
GO:0000120	RNA polymerase I transcription regulator complex	cellular_component	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.
GO:0000121	glycerol-1-phosphatase activity	molecular_function	Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate.
GO:0000122	negative regulation of transcription by RNA polymerase II	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
GO:0000123	histone acetyltransferase complex	cellular_component	A protein complex that possesses histone acetyltransferase activity.
GO:0000124	SAGA complex	cellular_component	A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
GO:0000126	transcription factor TFIIIB complex	cellular_component	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.
GO:0000127	transcription factor TFIIIC complex	cellular_component	A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.
GO:0000128	flocculation	biological_process	The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.
GO:0000131	incipient cellular bud site	cellular_component	The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
GO:0000132	establishment of mitotic spindle orientation	biological_process	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
GO:0000133	polarisome	cellular_component	Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.
GO:0000136	mannan polymerase complex	cellular_component	A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
GO:0000137	Golgi cis cisterna	cellular_component	The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
GO:0000138	Golgi trans cisterna	cellular_component	The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
GO:0000139	Golgi membrane	cellular_component	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
GO:0000140	acylglycerone-phosphate reductase activity	molecular_function	Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H+.
GO:0000142	cellular bud neck contractile ring	cellular_component	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.
GO:0000144	cellular bud neck septin ring	cellular_component	A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.
GO:0000145	exocyst	cellular_component	A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
GO:0000146	microfilament motor activity	molecular_function	A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.
GO:0000147	actin cortical patch assembly	biological_process	Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
GO:0000148	1,3-beta-D-glucan synthase complex	cellular_component	A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.
GO:0000149	SNARE binding	molecular_function	Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
GO:0000150	DNA strand exchange activity	molecular_function	Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
GO:0000151	ubiquitin ligase complex	cellular_component	A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
GO:0000152	nuclear ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex found in the nucleus.
GO:0000153	cytoplasmic ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex found in the cytoplasm.
GO:0000154	rRNA modification	biological_process	The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.
GO:0000155	phosphorelay sensor kinase activity	molecular_function	Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
GO:0000156	phosphorelay response regulator activity	molecular_function	Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
GO:0000159	protein phosphatase type 2A complex	cellular_component	A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
GO:0000160	phosphorelay signal transduction system	biological_process	A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
GO:0000161	osmosensory signaling MAPK cascade	biological_process	The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.
GO:0000162	tryptophan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
GO:0000164	protein phosphatase type 1 complex	cellular_component	A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.
GO:0000165	MAPK cascade	biological_process	An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
GO:0000166	nucleotide binding	molecular_function	Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0000170	sphingosine hydroxylase activity	molecular_function	Catalysis of the hydroxylation of sphingolipid long chain bases.
GO:0000171	ribonuclease MRP activity	molecular_function	Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.
GO:0000172	ribonuclease MRP complex	cellular_component	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
GO:0000175	3'-5'-RNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
GO:0000176	nuclear exosome (RNase complex)	cellular_component	A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:0000177	cytoplasmic exosome (RNase complex)	cellular_component	A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:0000178	exosome (RNase complex)	cellular_component	A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	molecular_function	Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.
GO:0000182	rDNA binding	molecular_function	Binding to a DNA sequence encoding a ribosomal RNA.
GO:0000183	rDNA heterochromatin formation	biological_process	The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	biological_process	The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
GO:0000196	cell wall integrity MAPK cascade	biological_process	A MAPK cascade that contributes to cell wall organization or biogenesis.
GO:0000209	protein polyubiquitination	biological_process	Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
GO:0000210	NAD+ diphosphatase activity	molecular_function	Catalysis of the reaction: NAD+ + H2O = AMP + NMN.
GO:0000212	meiotic spindle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
GO:0000213	tRNA-intron endonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
GO:0000214	tRNA-intron endonuclease complex	cellular_component	A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
GO:0000215	tRNA 2'-phosphotransferase activity	molecular_function	Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.
GO:0000217	DNA secondary structure binding	molecular_function	Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.
GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain	cellular_component	The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	cellular_component	The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
GO:0000222	plasma membrane proton-transporting V-type ATPase, V0 domain	cellular_component	The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.
GO:0000223	plasma membrane proton-transporting V-type ATPase, V1 domain	cellular_component	The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.
GO:0000224	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	molecular_function	Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
GO:0000225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
GO:0000226	microtubule cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GO:0000227	oxaloacetate secondary active transmembrane transporter activity	molecular_function	Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0000228	nuclear chromosome	cellular_component	A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
GO:0000234	phosphoethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.
GO:0000235	astral microtubule	cellular_component	Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
GO:0000236	mitotic prometaphase	biological_process	The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.
GO:0000237	leptotene	biological_process	The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.
GO:0000238	zygotene	biological_process	The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.
GO:0000239	pachytene	biological_process	The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
GO:0000240	diplotene	biological_process	The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
GO:0000241	diakinesis	biological_process	The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.
GO:0000242	pericentriolar material	cellular_component	A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
GO:0000243	commitment complex	cellular_component	A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
GO:0000244	spliceosomal tri-snRNP complex assembly	biological_process	The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
GO:0000245	spliceosomal complex assembly	biological_process	The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
GO:0000246	delta24(24-1) sterol reductase activity	molecular_function	Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H+ + NADPH.
GO:0000247	C-8 sterol isomerase activity	molecular_function	Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.
GO:0000248	C-5 sterol desaturase activity	molecular_function	Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
GO:0000249	C-22 sterol desaturase activity	molecular_function	Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
GO:0000250	lanosterol synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
GO:0000252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity	molecular_function	Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.
GO:0000253	3-keto sterol reductase activity	molecular_function	Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+.
GO:0000254	C-4 methylsterol oxidase activity	molecular_function	Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H+ + 3 O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O.
GO:0000255	allantoin metabolic process	biological_process	The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.
GO:0000256	allantoin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
GO:0000257	nitrilase activity	molecular_function	Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.
GO:0000262	mitochondrial chromosome	cellular_component	A chromosome found in the mitochondrion of a eukaryotic cell.
GO:0000266	mitochondrial fission	biological_process	The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GO:0000268	peroxisome targeting sequence binding	molecular_function	Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome.
GO:0000269	toxin export channel activity	molecular_function	Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0000270	peptidoglycan metabolic process	biological_process	The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
GO:0000271	polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0000272	polysaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0000274	mitochondrial proton-transporting ATP synthase, stator stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)	cellular_component	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	cellular_component	All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
GO:0000277	[cytochrome c]-lysine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.
GO:0000278	mitotic cell cycle	biological_process	Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0000279	M phase	biological_process	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.
GO:0000280	nuclear division	biological_process	The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
GO:0000281	mitotic cytokinesis	biological_process	A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
GO:0000282	cellular bud site selection	biological_process	The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity	molecular_function	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H+.
GO:0000286	alanine dehydrogenase activity	molecular_function	Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+.
GO:0000287	magnesium ion binding	molecular_function	Binding to a magnesium (Mg) ion.
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological_process	A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	biological_process	Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	biological_process	Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	biological_process	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.
GO:0000292	RNA fragment catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.
GO:0000293	ferric-chelate reductase activity	molecular_function	Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor.
GO:0000294	nuclear-transcribed mRNA catabolic process, RNase MRP-dependent	biological_process	A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends.
GO:0000295	adenine nucleotide transmembrane transporter activity	molecular_function	Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.
GO:0000296	spermine transport	biological_process	The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0000297	spermine transmembrane transporter activity	molecular_function	Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
GO:0000298	endopolyphosphatase activity	molecular_function	Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.
GO:0000301	retrograde transport, vesicle recycling within Golgi	biological_process	The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.
GO:0000302	response to reactive oxygen species	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
GO:0000303	response to superoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
GO:0000304	response to singlet oxygen	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
GO:0000305	response to oxygen radical	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	cellular_component	Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex	cellular_component	Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.
GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.
GO:0000310	xanthine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.
GO:0000311	plastid large ribosomal subunit	cellular_component	The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
GO:0000312	plastid small ribosomal subunit	cellular_component	The smaller of the two subunits of a plastid ribosome.
GO:0000313	organellar ribosome	cellular_component	A ribosome contained within a subcellular membrane-bounded organelle.
GO:0000314	organellar small ribosomal subunit	cellular_component	The smaller of the two subunits of an organellar ribosome.
GO:0000315	organellar large ribosomal subunit	cellular_component	The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
GO:0000316	sulfite transport	biological_process	The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0000319	sulfite transmembrane transporter activity	molecular_function	Enables the transfer of sulfite ions from one side of a membrane to the other.
GO:0000320	re-entry into mitotic cell cycle	biological_process	The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.
GO:0000321	re-entry into mitotic cell cycle after pheromone arrest	biological_process	The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.
GO:0000322	storage vacuole	cellular_component	A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.
GO:0000323	lytic vacuole	cellular_component	A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
GO:0000324	fungal-type vacuole	cellular_component	A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
GO:0000325	plant-type vacuole	cellular_component	A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
GO:0000326	protein storage vacuole	cellular_component	A storage vacuole that contains a lytic vacuole; identified in plants.
GO:0000327	lytic vacuole within protein storage vacuole	cellular_component	A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.
GO:0000328	fungal-type vacuole lumen	cellular_component	The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.
GO:0000329	fungal-type vacuole membrane	cellular_component	The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
GO:0000330	plant-type vacuole lumen	cellular_component	The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.
GO:0000331	contractile vacuole	cellular_component	A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory.
GO:0000332	template for synthesis of G-rich strand of telomere DNA activity	molecular_function	Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.
GO:0000333	telomerase catalytic core complex	cellular_component	The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.
GO:0000334	3-hydroxyanthranilate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
GO:0000338	protein deneddylation	biological_process	The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
GO:0000339	RNA cap binding	molecular_function	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
GO:0000340	RNA 7-methylguanosine cap binding	molecular_function	Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
GO:0000341	RNA trimethylguanosine cap binding	molecular_function	Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
GO:0000342	RNA cap 4 binding	molecular_function	Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.
GO:0000343	plastid-encoded plastid RNA polymerase complex A	cellular_component	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.
GO:0000344	plastid-encoded plastid RNA polymerase complex B	cellular_component	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.
GO:0000345	cytosolic DNA-directed RNA polymerase complex	cellular_component	The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.
GO:0000346	transcription export complex	cellular_component	The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.
GO:0000347	THO complex	cellular_component	The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.
GO:0000348	mRNA branch site recognition	biological_process	Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
GO:0000349	generation of catalytic spliceosome for first transesterification step	biological_process	Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
GO:0000350	generation of catalytic spliceosome for second transesterification step	biological_process	Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
GO:0000352	trans assembly of SL-containing precatalytic spliceosome	biological_process	Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.
GO:0000353	formation of quadruple SL/U4/U5/U6 snRNP	biological_process	Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.
GO:0000354	cis assembly of pre-catalytic spliceosome	biological_process	Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
GO:0000365	mRNA trans splicing, via spliceosome	biological_process	The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
GO:0000366	intergenic mRNA trans splicing	biological_process	The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.
GO:0000372	Group I intron splicing	biological_process	The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
GO:0000373	Group II intron splicing	biological_process	The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.
GO:0000374	Group III intron splicing	biological_process	The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.
GO:0000375	RNA splicing, via transesterification reactions	biological_process	Splicing of RNA via a series of two transesterification reactions.
GO:0000376	RNA splicing, via transesterification reactions with guanosine as nucleophile	biological_process	Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	biological_process	Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.
GO:0000378	RNA exon ligation	biological_process	The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.
GO:0000379	tRNA-type intron splice site recognition and cleavage	biological_process	RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.
GO:0000380	alternative mRNA splicing, via spliceosome	biological_process	The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	biological_process	Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
GO:0000384	first spliceosomal transesterification activity	molecular_function	Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.
GO:0000386	second spliceosomal transesterification activity	molecular_function	Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
GO:0000387	spliceosomal snRNP assembly	biological_process	The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.
GO:0000388	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	biological_process	Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
GO:0000389	mRNA 3'-splice site recognition	biological_process	Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.
GO:0000390	spliceosomal complex disassembly	biological_process	Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.
GO:0000393	spliceosomal conformational changes to generate catalytic conformation	biological_process	Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	biological_process	Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
GO:0000395	mRNA 5'-splice site recognition	biological_process	Recognition of the intron 5'-splice site by components of the assembling spliceosome.
GO:0000398	mRNA splicing, via spliceosome	biological_process	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
GO:0000399	cellular bud neck septin structure	cellular_component	Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.
GO:0000400	four-way junction DNA binding	molecular_function	Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
GO:0000401	open form four-way junction DNA binding	molecular_function	Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.
GO:0000402	crossed form four-way junction DNA binding	molecular_function	Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.
GO:0000403	Y-form DNA binding	molecular_function	Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.
GO:0000404	heteroduplex DNA loop binding	molecular_function	Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.
GO:0000405	bubble DNA binding	molecular_function	Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.
GO:0000406	double-strand/single-strand DNA junction binding	molecular_function	Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA.
GO:0000407	phagophore assembly site	cellular_component	Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
GO:0000408	EKC/KEOPS complex	cellular_component	A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
GO:0000409	regulation of transcription by galactose	biological_process	Any process involving galactose that modulates the frequency, rate or extent or transcription.
GO:0000410	carbon catabolite repression of transcription by galactose	biological_process	A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
GO:0000411	positive regulation of transcription by galactose	biological_process	Any process involving galactose that activates or increases the rate of transcription.
GO:0000412	histone peptidyl-prolyl isomerization	biological_process	The modification of a histone by cis-trans isomerization of a proline residue.
GO:0000413	protein peptidyl-prolyl isomerization	biological_process	The modification of a protein by cis-trans isomerization of a proline residue.
GO:0000417	HIR complex	cellular_component	A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.
GO:0000418	RNA polymerase IV complex	cellular_component	RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.
GO:0000419	RNA polymerase V complex	cellular_component	RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.
GO:0000421	autophagosome membrane	cellular_component	The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
GO:0000422	autophagy of mitochondrion	biological_process	The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
GO:0000423	mitophagy	biological_process	The selective autophagy process in which a mitochondrion is degraded by macroautophagy.
GO:0000424	micromitophagy	biological_process	Degradation of a mitochondrion by lysosomal microautophagy.
GO:0000425	pexophagy	biological_process	The selective autophagy process in which a peroxisome is degraded by macroautophagy.
GO:0000426	micropexophagy	biological_process	Degradation of a peroxisome by lysosomal microautophagy.
GO:0000427	plastid-encoded plastid RNA polymerase complex	cellular_component	An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.
GO:0000428	DNA-directed RNA polymerase complex	cellular_component	A protein complex that possesses DNA-directed RNA polymerase activity.
GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter	biological_process	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose	biological_process	Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0000431	regulation of transcription from RNA polymerase II promoter by galactose	biological_process	Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	biological_process	Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.
GO:0000433	carbon catabolite repression of transcription from RNA polymerase II promoter by glucose	biological_process	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
GO:0000434	carbon catabolite repression of transcription from RNA polymerase II promoter by galactose	biological_process	Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose	biological_process	Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.
GO:0000436	carbon catabolite activation of transcription from RNA polymerase II promoter	biological_process	Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0000437	carbon catabolite repression of transcription from RNA polymerase II promoter	biological_process	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
GO:0000438	core TFIIH complex portion of holo TFIIH complex	cellular_component	The core TFIIH complex when it is part of the general transcription factor TFIIH.
GO:0000439	transcription factor TFIIH core complex	cellular_component	The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
GO:0000440	core TFIIH complex portion of NEF3 complex	cellular_component	The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).
GO:0000444	MIS12/MIND type complex	cellular_component	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
GO:0000445	THO complex part of transcription export complex	cellular_component	The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits.
GO:0000446	nucleoplasmic THO complex	cellular_component	The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000449	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	biological_process	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0000450	cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.
GO:0000451	rRNA 2'-O-methylation	biological_process	The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.
GO:0000452	snoRNA guided rRNA 2'-O-methylation	biological_process	The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.
GO:0000454	snoRNA guided rRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
GO:0000455	enzyme-directed rRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.
GO:0000457	endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	biological_process	Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0000458	endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	biological_process	Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0000460	maturation of 5.8S rRNA	biological_process	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
GO:0000464	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.
GO:0000465	exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
GO:0000468	generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000470	maturation of LSU-rRNA	biological_process	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
GO:0000471	endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
GO:0000473	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
GO:0000474	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
GO:0000475	maturation of 2S rRNA	biological_process	Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.
GO:0000476	maturation of 4.5S rRNA	biological_process	Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.
GO:0000477	generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae.
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.
GO:0000481	maturation of 5S rRNA	biological_process	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.
GO:0000482	maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
GO:0000483	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species.
GO:0000484	cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000485	cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000486	cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
GO:0000487	maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	biological_process	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
GO:0000488	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
GO:0000489	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
GO:0000491	small nucleolar ribonucleoprotein complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.
GO:0000492	box C/D snoRNP assembly	biological_process	The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.
GO:0000493	box H/ACA snoRNP assembly	biological_process	The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
GO:0000494	box C/D RNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a box C/D RNA molecule.
GO:0000495	box H/ACA RNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.
GO:0000497	DNA template activity	molecular_function	Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
GO:0000500	RNA polymerase I upstream activating factor complex	cellular_component	A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.
GO:0000502	proteasome complex	cellular_component	A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	cellular_component	An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.
GO:0000510	H3-H4 histone complex chaperone activity	molecular_function	A histone chaperone that carries a H3-H4 histone complex.
GO:0000511	H2A-H2B histone complex chaperone activity	molecular_function	A histone chaperone that carries a H2A-H2B histone complex.
GO:0000512	lncRNA-mediated post-transcriptional gene silencing	biological_process	A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs.
GO:0000513	actin severing activator activity	molecular_function	Binds to and increases the activity of a actin severing protein.
GO:0000514	3-sulfino-L-alanine: proton, glutamate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-sulfino-L-alanine (cysteinesulfinate) (out) + H+(in) + L-glutamate(in) = 3-sulfino-L-alanine(in) + H+(out) + L-glutamate(out).
GO:0000515	aspartate:glutamate, proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-aspartate(in) + L-glutamate(out) = H+(in) + L-aspartate(out) + L-glutamate(in).
GO:0000578	embryonic axis specification	biological_process	The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.
GO:0000700	mismatch base pair DNA N-glycosylase activity	molecular_function	Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	molecular_function	Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
GO:0000702	oxidized base lesion DNA N-glycosylase activity	molecular_function	Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	molecular_function	Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
GO:0000704	pyrimidine dimer DNA N-glycosylase activity	molecular_function	Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
GO:0000705	achiasmate meiosis I	biological_process	The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.
GO:0000706	meiotic DNA double-strand break processing	biological_process	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
GO:0000707	meiotic DNA recombinase assembly	biological_process	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.
GO:0000708	meiotic strand invasion	biological_process	The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.
GO:0000709	meiotic joint molecule formation	biological_process	The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.
GO:0000710	meiotic mismatch repair	biological_process	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.
GO:0000711	meiotic DNA repair synthesis	biological_process	During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.
GO:0000712	resolution of meiotic recombination intermediates	biological_process	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.
GO:0000713	meiotic heteroduplex formation	biological_process	During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.
GO:0000714	meiotic strand displacement	biological_process	The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.
GO:0000715	nucleotide-excision repair, DNA damage recognition	biological_process	The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.
GO:0000716	transcription-coupled nucleotide-excision repair, DNA damage recognition	biological_process	The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	biological_process	The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.
GO:0000718	nucleotide-excision repair, DNA damage removal	biological_process	The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.
GO:0000719	photoreactive repair	biological_process	The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	biological_process	The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
GO:0000721	(R,R)-butanediol dehydrogenase activity	molecular_function	Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.
GO:0000722	telomere maintenance via recombination	biological_process	Any recombinational process that contributes to the maintenance of proper telomeric length.
GO:0000723	telomere maintenance	biological_process	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
GO:0000724	double-strand break repair via homologous recombination	biological_process	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
GO:0000725	recombinational repair	biological_process	A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.
GO:0000727	double-strand break repair via break-induced replication	biological_process	The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.
GO:0000729	DNA double-strand break processing	biological_process	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.
GO:0000730	DNA recombinase assembly	biological_process	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.
GO:0000731	DNA synthesis involved in DNA repair	biological_process	Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
GO:0000732	strand displacement	biological_process	The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.
GO:0000735	removal of nonhomologous ends	biological_process	The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.
GO:0000736	double-strand break repair via single-strand annealing, removal of nonhomologous ends	biological_process	During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.
GO:0000740	nuclear membrane fusion	biological_process	The joining of 2 or more lipid bilayer membranes that surround the nucleus.
GO:0000741	karyogamy	biological_process	The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.
GO:0000742	karyogamy involved in conjugation with cellular fusion	biological_process	During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.
GO:0000743	nuclear migration involved in conjugation with cellular fusion	biological_process	The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.
GO:0000744	karyogamy involved in conjugation with mutual genetic exchange	biological_process	During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena.
GO:0000745	nuclear migration involved in conjugation with mutual genetic exchange	biological_process	The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion.
GO:0000747	conjugation with cellular fusion	biological_process	A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.
GO:0000748	conjugation with mutual genetic exchange	biological_process	A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange.
GO:0000749	response to pheromone triggering conjugation with cellular fusion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
GO:0000750	pheromone-dependent signal transduction involved in conjugation with cellular fusion	biological_process	A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
GO:0000751	mitotic cell cycle G1 arrest in response to pheromone	biological_process	The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.
GO:0000752	agglutination involved in conjugation with cellular fusion	biological_process	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.
GO:0000753	cell morphogenesis involved in conjugation with cellular fusion	biological_process	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.
GO:0000754	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	biological_process	In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.
GO:0000755	cytogamy	biological_process	During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
GO:0000756	response to pheromone regulating conjugation with mutual genetic exchange	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.
GO:0000758	agglutination involved in conjugation with mutual genetic exchange	biological_process	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism.
GO:0000760	adaptation to pheromone regulating conjugation with mutual genetic exchange	biological_process	In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.
GO:0000761	conjugant formation	biological_process	During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.
GO:0000762	pheromone-induced unidirectional conjugation	biological_process	Unidirectional transfer of genetic information triggered by to a pheromone signal.
GO:0000765	response to pheromone regulating pheromone-induced unidirectional conjugation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.
GO:0000766	negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation	biological_process	In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses.
GO:0000768	syncytium formation by plasma membrane fusion	biological_process	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0000769	syncytium formation by mitosis without cytokinesis	biological_process	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.
GO:0000770	peptide pheromone export	biological_process	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.
GO:0000772	mating pheromone activity	molecular_function	The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.
GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
GO:0000774	adenyl-nucleotide exchange factor activity	molecular_function	Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.
GO:0000775	chromosome, centromeric region	cellular_component	The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
GO:0000776	kinetochore	cellular_component	A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
GO:0000779	condensed chromosome, centromeric region	cellular_component	The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
GO:0000781	chromosome, telomeric region	cellular_component	The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).
GO:0000782	telomere cap complex	cellular_component	A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome.
GO:0000783	nuclear telomere cap complex	cellular_component	A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.
GO:0000785	chromatin	cellular_component	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
GO:0000786	nucleosome	cellular_component	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
GO:0000791	euchromatin	cellular_component	A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation.
GO:0000792	heterochromatin	cellular_component	A compact and highly condensed form of chromatin that is refractory to transcription.
GO:0000793	condensed chromosome	cellular_component	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
GO:0000794	condensed nuclear chromosome	cellular_component	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
GO:0000795	synaptonemal complex	cellular_component	A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
GO:0000796	condensin complex	cellular_component	A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.
GO:0000800	lateral element	cellular_component	A proteinaceous core found between sister chromatids during meiotic prophase.
GO:0000801	central element	cellular_component	A structural unit of the synaptonemal complex found between the lateral elements.
GO:0000802	transverse filament	cellular_component	A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.
GO:0000803	sex chromosome	cellular_component	A chromosome involved in sex determination.
GO:0000804	W chromosome	cellular_component	The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.
GO:0000805	X chromosome	cellular_component	The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.
GO:0000806	Y chromosome	cellular_component	The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.
GO:0000807	Z chromosome	cellular_component	The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.
GO:0000808	origin recognition complex	cellular_component	A multisubunit complex that is located at the replication origins of a chromosome.
GO:0000809	cytoplasmic origin of replication recognition complex	cellular_component	A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.
GO:0000810	diacylglycerol diphosphate phosphatase activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.
GO:0000811	GINS complex	cellular_component	A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.
GO:0000812	Swr1 complex	cellular_component	A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
GO:0000813	ESCRT I complex	cellular_component	An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
GO:0000814	ESCRT II complex	cellular_component	An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
GO:0000815	ESCRT III complex	cellular_component	A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).
GO:0000817	COMA complex	cellular_component	A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.
GO:0000819	sister chromatid segregation	biological_process	The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.
GO:0000820	regulation of glutamine family amino acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
GO:0000821	regulation of arginine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
GO:0000822	inositol hexakisphosphate binding	molecular_function	Binding to inositol hexakisphosphate.
GO:0000823	inositol-1,4,5-trisphosphate 6-kinase activity	molecular_function	Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H+.
GO:0000824	inositol tetrakisphosphate 3-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.
GO:0000825	inositol tetrakisphosphate 6-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
GO:0000828	inositol hexakisphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
GO:0000829	inositol heptakisphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
GO:0000830	inositol hexakisphosphate 4-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.
GO:0000831	inositol hexakisphosphate 6-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.
GO:0000832	inositol hexakisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.
GO:0000833	inositol heptakisphosphate 4-kinase activity	molecular_function	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate.
GO:0000834	inositol heptakisphosphate 6-kinase activity	molecular_function	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.
GO:0000835	ER ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex found in the ER.
GO:0000836	Hrd1p ubiquitin ligase complex	cellular_component	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
GO:0000837	Doa10p ubiquitin ligase complex	cellular_component	A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
GO:0000838	Hrd1p ubiquitin ligase ERAD-M complex	cellular_component	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex	cellular_component	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
GO:0000900	mRNA regulatory element binding translation repressor activity	molecular_function	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
GO:0000901	translation repressor activity, non-nucleic acid binding	molecular_function	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.
GO:0000902	cell morphogenesis	biological_process	The developmental process in which the size or shape of a cell is generated and organized.
GO:0000905	sporocarp development involved in asexual reproduction	biological_process	The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.
GO:0000906	6,7-dimethyl-8-ribityllumazine synthase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.
GO:0000907	sulfonate dioxygenase activity	molecular_function	Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.
GO:0000908	taurine dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.
GO:0000909	sporocarp development involved in sexual reproduction	biological_process	The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
GO:0000910	cytokinesis	biological_process	The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
GO:0000911	cytokinesis by cell plate formation	biological_process	The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.
GO:0000912	assembly of actomyosin apparatus involved in cytokinesis	biological_process	The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
GO:0000913	preprophase band assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.
GO:0000914	phragmoplast assembly	biological_process	The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).
GO:0000915	actomyosin contractile ring assembly	biological_process	The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
GO:0000916	actomyosin contractile ring contraction	biological_process	The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
GO:0000917	division septum assembly	biological_process	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
GO:0000918	division septum site selection	biological_process	The process of marking the site where a division septum will form.
GO:0000919	cell plate assembly	biological_process	The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.
GO:0000920	septum digestion after cytokinesis	biological_process	The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
GO:0000921	septin ring assembly	biological_process	The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
GO:0000922	spindle pole	cellular_component	Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
GO:0000923	equatorial microtubule organizing center	cellular_component	A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.
GO:0000930	gamma-tubulin complex	cellular_component	A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.
GO:0000931	gamma-tubulin ring complex	cellular_component	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.
GO:0000932	P-body	cellular_component	A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
GO:0000933	adventitious septum	cellular_component	A cell septum whose formation is independent of nuclear division.
GO:0000934	porous cell septum	cellular_component	A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.
GO:0000935	division septum	cellular_component	A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
GO:0000936	primary cell septum	cellular_component	A cell septum that forms following nuclear division.
GO:0000937	dolipore septum	cellular_component	A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).
GO:0000938	GARP complex	cellular_component	A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.
GO:0000939	inner kinetochore	cellular_component	The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
GO:0000940	outer kinetochore	cellular_component	The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
GO:0000943	retrotransposon nucleocapsid	cellular_component	A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.
GO:0000947	amino acid catabolic process to alcohol via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
GO:0000948	amino acid catabolic process to carboxylic acid via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
GO:0000949	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
GO:0000950	branched-chain amino acid catabolic process to alcohol via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
GO:0000951	methionine catabolic process to 3-methylthiopropanol	biological_process	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
GO:0000952	aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
GO:0000953	branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
GO:0000954	methionine catabolic process to 3-methylthiopropanoate	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
GO:0000955	amino acid catabolic process via Ehrlich pathway	biological_process	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.
GO:0000956	nuclear-transcribed mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
GO:0000957	mitochondrial RNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GO:0000958	mitochondrial mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GO:0000959	mitochondrial RNA metabolic process	biological_process	The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GO:0000960	regulation of mitochondrial RNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GO:0000961	negative regulation of mitochondrial RNA catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GO:0000962	positive regulation of mitochondrial RNA catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GO:0000963	mitochondrial RNA processing	biological_process	The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
GO:0000964	mitochondrial RNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
GO:0000965	mitochondrial RNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
GO:0000966	RNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of an RNA molecule.
GO:0000967	rRNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of an rRNA molecule.
GO:0000968	tRNA exon ligation	biological_process	An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.
GO:0000969	tRNA exon ligation utilizing ATP as source of linkage phosphate	biological_process	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species.
GO:0000970	tRNA exon ligation utilizing GTP as source of linkage phosphate	biological_process	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process.
GO:0000971	tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate	biological_process	A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans.
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	biological_process	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.
GO:0000973	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery	biological_process	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.
GO:0000974	Prp19 complex	cellular_component	A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
GO:0000976	transcription cis-regulatory region binding	molecular_function	Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	molecular_function	Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	molecular_function	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
GO:0000987	cis-regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter.
GO:0000992	RNA polymerase III cis-regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.
GO:0000993	RNA polymerase II complex binding	molecular_function	Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
GO:0000994	RNA polymerase III core binding	molecular_function	Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
GO:0000995	RNA polymerase III general transcription initiation factor activity	molecular_function	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.
GO:0001000	bacterial-type RNA polymerase core enzyme binding	molecular_function	Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.
GO:0001001	mitochondrial single-subunit type RNA polymerase binding	molecular_function	Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
GO:0001002	RNA polymerase III type 1 promoter sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
GO:0001003	RNA polymerase III type 2 promoter sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
GO:0001006	RNA polymerase III type 3 promoter sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
GO:0001010	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	molecular_function	The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.
GO:0001014	snoRNA transcription by RNA polymerase III	biological_process	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.
GO:0001015	snoRNA transcription by RNA polymerase II	biological_process	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
GO:0001016	RNA polymerase III transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
GO:0001018	mitochondrial promoter sequence-specific DNA binding	molecular_function	Binding to a DNA region that controls the transcription of the mitochondrial DNA.
GO:0001019	plastid promoter transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to a DNA region that controls transcription by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
GO:0001025	RNA polymerase III general transcription initiation factor binding	molecular_function	Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III.
GO:0001039	RNA polymerase III hybrid type promoter sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
GO:0001042	RNA polymerase I core binding	molecular_function	Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
GO:0001046	core promoter sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
GO:0001048	RNA polymerase IV core binding	molecular_function	Binding to RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production.
GO:0001049	RNA polymerase V core binding	molecular_function	Binding to RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing.
GO:0001050	single-subunit type RNA polymerase binding	molecular_function	Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
GO:0001051	plastid single-subunit type RNA polymerase binding	molecular_function	Binding to a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
GO:0001052	plastid PEP RNA polymerase core enzyme binding	molecular_function	Binding to a bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit.
GO:0001054	RNA polymerase I activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001055	RNA polymerase II activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001056	RNA polymerase III activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001057	RNA polymerase IV activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001058	RNA polymerase V activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001059	transcription by RNA polymerase IV	biological_process	The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter.
GO:0001060	transcription by RNA polymerase V	biological_process	The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter.
GO:0001064	single subunit type RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001065	mitochondrial single subunit type RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001066	plastid single subunit type RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0001067	transcription regulatory region nucleic acid binding	molecular_function	Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
GO:0001068	transcription regulatory region RNA binding	molecular_function	Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.
GO:0001069	regulatory region RNA binding	molecular_function	Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
GO:0001070	RNA-binding transcription regulator activity	molecular_function	A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.
GO:0001072	transcription antitermination factor activity, RNA binding	molecular_function	Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.
GO:0001073	transcription antitermination factor activity, DNA binding	molecular_function	Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.
GO:0001079	nitrogen catabolite regulation of transcription from RNA polymerase II promoter	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
GO:0001080	nitrogen catabolite activation of transcription from RNA polymerase II promoter	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
GO:0001081	nitrogen catabolite repression of transcription from RNA polymerase II promoter	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
GO:0001091	RNA polymerase II general transcription initiation factor binding	molecular_function	Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
GO:0001092	TFIIA-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
GO:0001093	TFIIB-class transcription factor binding	molecular_function	Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
GO:0001094	TFIID-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
GO:0001095	TFIIE-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
GO:0001096	TFIIF-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
GO:0001097	TFIIH-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
GO:0001098	basal transcription machinery binding	molecular_function	Binding to a component of the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.
GO:0001099	basal RNA polymerase II transcription machinery binding	molecular_function	Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.
GO:0001100	negative regulation of exit from mitosis	biological_process	Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
GO:0001101	response to acid chemical	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GO:0001108	bacterial-type RNA polymerase holo enzyme binding	molecular_function	Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.
GO:0001109	promoter clearance during DNA-templated transcription	biological_process	Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
GO:0001110	RNA polymerase III promoter clearance	biological_process	A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.
GO:0001111	RNA polymerase II promoter clearance	biological_process	A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
GO:0001112	DNA-templated transcription open complex formation	biological_process	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
GO:0001113	transcription open complex formation at RNA polymerase II promoter	biological_process	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
GO:0001114	protein-DNA-RNA complex	cellular_component	A macromolecular complex containing protein, DNA, and RNA molecules.
GO:0001115	protein-DNA-RNA complex organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex.
GO:0001116	protein-DNA-RNA complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.
GO:0001117	protein-DNA-RNA complex disassembly	biological_process	The disaggregation of a protein-DNA-RNA complex into its constituent components.
GO:0001118	transcription ternary complex disassembly	biological_process	The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.
GO:0001119	protein-DNA-RNA complex remodeling	biological_process	The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.
GO:0001120	protein-DNA complex remodeling	biological_process	The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex.
GO:0001139	RNA polymerase II complex recruiting activity	molecular_function	Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
GO:0001147	transcription termination site sequence-specific DNA binding	molecular_function	Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
GO:0001154	TFIIIB-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
GO:0001155	TFIIIA-class transcription factor binding	molecular_function	Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters.
GO:0001156	TFIIIC-class transcription factor complex binding	molecular_function	Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to an intronic DNA sequence that regulates the transcription of the transcript it is contained within.
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	molecular_function	Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.
GO:0001165	RNA polymerase I cis-regulatory region sequence-specific DNA binding	molecular_function	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element).
GO:0001171	reverse transcription	biological_process	A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.
GO:0001172	RNA-templated transcription	biological_process	The synthesis of an RNA transcript from an RNA template.
GO:0001173	DNA-templated transcriptional start site selection	biological_process	Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
GO:0001174	transcriptional start site selection at RNA polymerase II promoter	biological_process	Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
GO:0001175	transcriptional start site selection at RNA polymerase III promoter	biological_process	Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
GO:0001177	regulation of transcription open complex formation at RNA polymerase II promoter	biological_process	Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter	biological_process	Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
GO:0001179	RNA polymerase I general transcription initiation factor binding	molecular_function	Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I.
GO:0001181	RNA polymerase I general transcription initiation factor activity	molecular_function	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.
GO:0001182	RNA polymerase I promoter clearance	biological_process	A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
GO:0001188	RNA polymerase I preinitiation complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter.
GO:0001192	maintenance of transcriptional fidelity during transcription elongation	biological_process	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
GO:0001193	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II	biological_process	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.
GO:0001195	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III	biological_process	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.
GO:0001216	DNA-binding transcription activator activity	molecular_function	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
GO:0001217	DNA-binding transcription repressor activity	molecular_function	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
GO:0001221	transcription coregulator binding	molecular_function	Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
GO:0001222	transcription corepressor binding	molecular_function	Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
GO:0001223	transcription coactivator binding	molecular_function	Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	molecular_function	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	molecular_function	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
GO:0001325	formation of extrachromosomal circular DNA	biological_process	Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
GO:0001326	replication of extrachromosomal circular DNA	biological_process	Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
GO:0001400	mating projection base	cellular_component	The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.
GO:0001401	SAM complex	cellular_component	A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.
GO:0001402	signal transduction involved in filamentous growth	biological_process	Relaying of environmental signals promoting filamentous growth.
GO:0001403	invasive growth in response to glucose limitation	biological_process	A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
GO:0001405	PAM complex, Tim23 associated import motor	cellular_component	Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.
GO:0001406	glycerophosphodiester transmembrane transporter activity	molecular_function	Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
GO:0001407	glycerophosphodiester transmembrane transport	biological_process	The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
GO:0001408	guanine nucleotide transport	biological_process	The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0001409	guanine nucleotide transmembrane transporter activity	molecular_function	Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.
GO:0001410	chlamydospore formation	biological_process	The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans.
GO:0001411	hyphal tip	cellular_component	The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
GO:0001501	skeletal system development	biological_process	The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
GO:0001502	cartilage condensation	biological_process	The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
GO:0001503	ossification	biological_process	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
GO:0001504	neurotransmitter uptake	biological_process	The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
GO:0001505	regulation of neurotransmitter levels	biological_process	Any process that modulates levels of neurotransmitter.
GO:0001507	acetylcholine catabolic process in synaptic cleft	biological_process	The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.
GO:0001508	action potential	biological_process	A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
GO:0001510	RNA methylation	biological_process	Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
GO:0001512	dihydronicotinamide riboside quinone reductase activity	molecular_function	Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.
GO:0001514	selenocysteine incorporation	biological_process	The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
GO:0001515	opioid peptide activity	molecular_function	Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.
GO:0001516	prostaglandin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.
GO:0001518	voltage-gated sodium channel complex	cellular_component	A sodium channel in a cell membrane whose opening is governed by the membrane potential.
GO:0001519	peptide amidation	biological_process	The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.
GO:0001520	outer dense fiber	cellular_component	A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.
GO:0001522	pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine within an RNA molecule.
GO:0001523	retinoid metabolic process	biological_process	The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
GO:0001525	angiogenesis	biological_process	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
GO:0001527	microfibril	cellular_component	Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins.
GO:0001530	lipopolysaccharide binding	molecular_function	Binding to a lipopolysaccharide.
GO:0001531	interleukin-21 receptor binding	molecular_function	Binding to an interleukin-21 receptor.
GO:0001532	interleukin-21 receptor activity	molecular_function	Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001533	cornified envelope	cellular_component	A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).
GO:0001534	radial spoke	cellular_component	Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.
GO:0001535	radial spoke head	cellular_component	Protein complex forming portion of the radial spoke that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary or flagellum axoneme.
GO:0001536	radial spoke stalk	cellular_component	Protein complex forming the elongated portion of the radial spoke between the base which binds to the A-tubule of each microtubule outer doublet and the neck which connects to the spoke head within the ciliary or flagellum axoneme.
GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.
GO:0001539	cilium or flagellum-dependent cell motility	biological_process	Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
GO:0001540	amyloid-beta binding	molecular_function	Binding to an amyloid-beta peptide/protein.
GO:0001541	ovarian follicle development	biological_process	The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
GO:0001542	ovulation from ovarian follicle	biological_process	The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.
GO:0001543	ovarian follicle rupture	biological_process	Disruption of theca cell layer releasing follicular fluid and/or the oocyte.
GO:0001544	initiation of primordial ovarian follicle growth	biological_process	Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).
GO:0001545	primary ovarian follicle growth	biological_process	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).
GO:0001546	preantral ovarian follicle growth	biological_process	Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
GO:0001547	antral ovarian follicle growth	biological_process	Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.
GO:0001548	follicular fluid formation in ovarian follicle antrum	biological_process	The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.
GO:0001549	cumulus cell differentiation	biological_process	The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.
GO:0001550	ovarian cumulus expansion	biological_process	Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.
GO:0001551	ovarian follicle endowment	biological_process	Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.
GO:0001552	ovarian follicle atresia	biological_process	A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.
GO:0001553	luteinization	biological_process	The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
GO:0001554	luteolysis	biological_process	The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
GO:0001555	oocyte growth	biological_process	The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
GO:0001556	oocyte maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
GO:0001558	regulation of cell growth	biological_process	Any process that modulates the frequency, rate, extent or direction of cell growth.
GO:0001560	regulation of cell growth by extracellular stimulus	biological_process	Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
GO:0001561	fatty acid alpha-oxidation	biological_process	A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
GO:0001562	response to protozoan	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
GO:0001563	detection of protozoan	biological_process	The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.
GO:0001565	phorbol ester receptor activity	molecular_function	Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.
GO:0001566	non-kinase phorbol ester receptor activity	molecular_function	Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.
GO:0001567	cholesterol 25-hydroxylase activity	molecular_function	Catalysis of the reaction: AH(2) + cholesterol + O2 = 25-hydroxycholesterol + A + H2O.
GO:0001568	blood vessel development	biological_process	The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
GO:0001569	branching involved in blood vessel morphogenesis	biological_process	The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
GO:0001570	vasculogenesis	biological_process	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
GO:0001571	non-tyrosine kinase fibroblast growth factor receptor activity	molecular_function	Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.
GO:0001572	lactosylceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
GO:0001573	ganglioside metabolic process	biological_process	The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
GO:0001574	ganglioside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
GO:0001575	globoside metabolic process	biological_process	The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
GO:0001576	globoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
GO:0001578	microtubule bundle formation	biological_process	A process that results in a parallel arrangement of microtubules.
GO:0001579	medium-chain fatty acid transport	biological_process	The directed movement of a medium-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	biological_process	The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
GO:0001581	detection of chemical stimulus involved in sensory perception of sour taste	biological_process	The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste	biological_process	The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.
GO:0001583	detection of chemical stimulus involved in sensory perception of salty taste	biological_process	The series of events required for a salty taste stimulus to be received and converted to a molecular signal.
GO:0001586	Gi/o-coupled serotonin receptor activity	molecular_function	Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
GO:0001587	Gq/11-coupled serotonin receptor activity	molecular_function	Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	molecular_function	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.
GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	molecular_function	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.
GO:0001594	trace-amine receptor activity	molecular_function	Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.
GO:0001595	angiotensin receptor activity	molecular_function	Combining with angiotensin to initiate a change in cell activity.
GO:0001596	angiotensin type I receptor activity	molecular_function	An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.
GO:0001601	peptide YY receptor activity	molecular_function	Combining with gut peptide YY to initiate a change in cell activity.
GO:0001602	pancreatic polypeptide receptor activity	molecular_function	Combining with pancreatic polypeptide PP to initiate a change in cell activity.
GO:0001604	urotensin II receptor activity	molecular_function	Combining with urotensin II to initiate a change in cell activity.
GO:0001605	adrenomedullin receptor activity	molecular_function	Combining with adrenomedullin to initiate a change in cell activity.
GO:0001607	neuromedin U receptor activity	molecular_function	Combining with neuromedin U to initiate a change in cell activity.
GO:0001608	G protein-coupled nucleotide receptor activity	molecular_function	Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001609	G protein-coupled adenosine receptor activity	molecular_function	Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001614	purinergic nucleotide receptor activity	molecular_function	Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001616	growth hormone secretagogue receptor activity	molecular_function	Combining with ghrelin to initiate a change in cell activity.
GO:0001618	virus receptor activity	molecular_function	Combining with a virus component and mediating entry of the virus into the cell.
GO:0001621	G protein-coupled ADP receptor activity	molecular_function	Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001626	nociceptin receptor activity	molecular_function	Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.
GO:0001631	cysteinyl leukotriene receptor activity	molecular_function	Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.
GO:0001632	leukotriene B4 receptor activity	molecular_function	Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.
GO:0001634	pituitary adenylate cyclase-activating polypeptide receptor activity	molecular_function	A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.
GO:0001635	calcitonin gene-related peptide receptor activity	molecular_function	Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.
GO:0001637	G protein-coupled chemoattractant receptor activity	molecular_function	Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001639	PLC activating G protein-coupled glutamate receptor activity	molecular_function	A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.
GO:0001640	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	molecular_function	Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
GO:0001641	group II metabotropic glutamate receptor activity	molecular_function	A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
GO:0001642	group III metabotropic glutamate receptor activity	molecular_function	A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.
GO:0001646	cAMP receptor activity	molecular_function	Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001647	G protein-coupled cytokinin receptor activity	molecular_function	Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0001648	proteinase-activated receptor activity	molecular_function	A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.
GO:0001649	osteoblast differentiation	biological_process	The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
GO:0001650	fibrillar center	cellular_component	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
GO:0001651	dense fibrillar component	cellular_component	A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.
GO:0001652	granular component	cellular_component	A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
GO:0001653	peptide receptor activity	molecular_function	Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
GO:0001654	eye development	biological_process	The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
GO:0001655	urogenital system development	biological_process	The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.
GO:0001656	metanephros development	biological_process	The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0001657	ureteric bud development	biological_process	The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
GO:0001658	branching involved in ureteric bud morphogenesis	biological_process	The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
GO:0001659	temperature homeostasis	biological_process	A homeostatic process in which an organism modulates its internal body temperature.
GO:0001660	fever generation	biological_process	The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.
GO:0001661	conditioned taste aversion	biological_process	A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
GO:0001662	behavioral fear response	biological_process	An acute behavioral change resulting from a perceived external threat.
GO:0001664	G protein-coupled receptor binding	molecular_function	Binding to a G protein-coupled receptor.
GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.
GO:0001666	response to hypoxia	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
GO:0001667	ameboidal-type cell migration	biological_process	Cell migration that is accomplished by extension and retraction of a pseudopodium.
GO:0001669	acrosomal vesicle	cellular_component	A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
GO:0001671	ATPase activator activity	molecular_function	Binds to and increases the activity of an ATP hydrolysis activity.
GO:0001673	male germ cell nucleus	cellular_component	The nucleus of a male germ cell, a reproductive cell in males.
GO:0001674	female germ cell nucleus	cellular_component	The nucleus of the female germ cell, a reproductive cell in females.
GO:0001675	acrosome assembly	biological_process	The formation of the acrosome from the spermatid Golgi.
GO:0001676	long-chain fatty acid metabolic process	biological_process	The chemical reactions and pathways involving a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0001677	formation of translation initiation ternary complex	biological_process	Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
GO:0001678	intracellular glucose homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of glucose within a cell.
GO:0001680	tRNA 3'-terminal CCA addition	biological_process	Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.
GO:0001681	sialate O-acetylesterase activity	molecular_function	Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.
GO:0001682	tRNA 5'-leader removal	biological_process	Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
GO:0001691	pseudophosphatase activity	molecular_function	Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
GO:0001692	histamine metabolic process	biological_process	The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0001694	histamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0001695	histamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0001696	gastric acid secretion	biological_process	The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
GO:0001697	histamine-induced gastric acid secretion	biological_process	The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.
GO:0001698	gastrin-induced gastric acid secretion	biological_process	The regulated release of gastric acid induced by the interaction of gastrin with its receptor.
GO:0001699	acetylcholine-induced gastric acid secretion	biological_process	The regulated release of gastric acid by parietal cells in response to acetylcholine.
GO:0001700	embryonic development via the syncytial blastoderm	biological_process	The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
GO:0001701	in utero embryonic development	biological_process	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
GO:0001702	gastrulation with mouth forming second	biological_process	A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.
GO:0001703	gastrulation with mouth forming first	biological_process	A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.
GO:0001704	formation of primary germ layer	biological_process	The formation of the ectoderm, mesoderm and endoderm during gastrulation.
GO:0001705	ectoderm formation	biological_process	The formation of ectoderm during gastrulation.
GO:0001706	endoderm formation	biological_process	The formation of the endoderm during gastrulation.
GO:0001707	mesoderm formation	biological_process	The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
GO:0001708	cell fate specification	biological_process	The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.
GO:0001709	cell fate determination	biological_process	The cellular developmental process involved in cell fate commitment that occurs after cell fate specification,  in which a cell is irreversibly committed to a cellular developmental fate which is heritable on cell division.
GO:0001710	mesodermal cell fate commitment	biological_process	The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
GO:0001711	endodermal cell fate commitment	biological_process	The cell differentiation process that results in commitment of a cell to become part of the endoderm.
GO:0001712	ectodermal cell fate commitment	biological_process	The cell differentiation process that results in commitment of a cell to become part of the ectoderm.
GO:0001713	ectodermal cell fate determination	biological_process	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0001714	endodermal cell fate specification	biological_process	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0001715	ectodermal cell fate specification	biological_process	The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0001716	L-amino-acid oxidase activity	molecular_function	Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.
GO:0001717	conversion of seryl-tRNAsec to selenocys-tRNAsec	biological_process	The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.
GO:0001720	conversion of lysyl-tRNA to pyrrolysyl-tRNA	biological_process	The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).
GO:0001725	stress fiber	cellular_component	A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
GO:0001726	ruffle	cellular_component	Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
GO:0001727	lipid kinase activity	molecular_function	Catalysis of the phosphorylation of a simple or complex lipid.
GO:0001729	ceramide kinase activity	molecular_function	Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
GO:0001730	2'-5'-oligoadenylate synthetase activity	molecular_function	Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.
GO:0001731	formation of translation preinitiation complex	biological_process	The joining of the small ribosomal subunit, ternary complex, and mRNA.
GO:0001732	formation of cytoplasmic translation initiation complex	biological_process	Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
GO:0001733	galactosylceramide sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.
GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.
GO:0001735	prenylcysteine oxidase activity	molecular_function	Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.
GO:0001736	establishment of planar polarity	biological_process	Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
GO:0001737	establishment of imaginal disc-derived wing hair orientation	biological_process	Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
GO:0001738	morphogenesis of a polarized epithelium	biological_process	The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
GO:0001739	sex chromatin	cellular_component	Chromatin that is part of a sex chromosome.
GO:0001740	Barr body	cellular_component	A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
GO:0001741	XY body	cellular_component	A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
GO:0001742	oenocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
GO:0001743	lens placode formation	biological_process	The initial developmental process that will lead to the formation of an eye.
GO:0001744	insect visual primordium formation	biological_process	Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.
GO:0001745	compound eye morphogenesis	biological_process	The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
GO:0001746	Bolwig's organ morphogenesis	biological_process	The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
GO:0001748	insect visual primordium development	biological_process	The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.
GO:0001750	photoreceptor outer segment	cellular_component	The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
GO:0001751	compound eye photoreceptor cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
GO:0001752	compound eye photoreceptor fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
GO:0001754	eye photoreceptor cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
GO:0001755	neural crest cell migration	biological_process	The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
GO:0001756	somitogenesis	biological_process	The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
GO:0001757	somite specification	biological_process	The process in which individual somites establish identity during embryogenesis.
GO:0001758	retinal dehydrogenase activity	molecular_function	Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
GO:0001759	organ induction	biological_process	The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.
GO:0001760	aminocarboxymuconate-semialdehyde decarboxylase activity	molecular_function	Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.
GO:0001761	beta-alanine transmembrane transporter activity	molecular_function	Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
GO:0001762	beta-alanine transport	biological_process	The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0001763	morphogenesis of a branching structure	biological_process	The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.
GO:0001764	neuron migration	biological_process	The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
GO:0001765	membrane raft assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
GO:0001766	membrane raft polarization	biological_process	The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.
GO:0001767	establishment of lymphocyte polarity	biological_process	The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
GO:0001768	establishment of T cell polarity	biological_process	The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
GO:0001769	establishment of B cell polarity	biological_process	The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.
GO:0001770	establishment of natural killer cell polarity	biological_process	The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.
GO:0001771	immunological synapse formation	biological_process	The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
GO:0001772	immunological synapse	cellular_component	An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
GO:0001773	myeloid dendritic cell activation	biological_process	The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0001774	microglial cell activation	biological_process	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0001775	cell activation	biological_process	A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.
GO:0001776	leukocyte homeostasis	biological_process	The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0001777	T cell homeostatic proliferation	biological_process	The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.
GO:0001778	plasma membrane repair	biological_process	The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
GO:0001779	natural killer cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.
GO:0001780	neutrophil homeostasis	biological_process	The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0001781	neutrophil apoptotic process	biological_process	Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
GO:0001782	B cell homeostasis	biological_process	The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0001783	B cell apoptotic process	biological_process	Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
GO:0001784	phosphotyrosine residue binding	molecular_function	Binding to a phosphorylated tyrosine residue within a protein.
GO:0001785	prostaglandin J receptor activity	molecular_function	Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.
GO:0001786	phosphatidylserine binding	molecular_function	Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
GO:0001787	natural killer cell proliferation	biological_process	The expansion of a natural killer cell population by cell division.
GO:0001788	antibody-dependent cellular cytotoxicity	biological_process	Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
GO:0001790	polymeric immunoglobulin binding	molecular_function	Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.
GO:0001791	IgM binding	molecular_function	Binding to an immunoglobulin of the IgM isotype.
GO:0001792	polymeric immunoglobulin receptor activity	molecular_function	Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001793	IgM receptor activity	molecular_function	Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001794	type IIa hypersensitivity	biological_process	An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.
GO:0001795	type IIb hypersensitivity	biological_process	An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.
GO:0001796	regulation of type IIa hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.
GO:0001797	negative regulation of type IIa hypersensitivity	biological_process	Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.
GO:0001798	positive regulation of type IIa hypersensitivity	biological_process	Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.
GO:0001799	regulation of type IIb hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.
GO:0001800	negative regulation of type IIb hypersensitivity	biological_process	Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.
GO:0001801	positive regulation of type IIb hypersensitivity	biological_process	Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.
GO:0001802	type III hypersensitivity	biological_process	An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.
GO:0001803	regulation of type III hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.
GO:0001804	negative regulation of type III hypersensitivity	biological_process	Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.
GO:0001805	positive regulation of type III hypersensitivity	biological_process	Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.
GO:0001806	type IV hypersensitivity	biological_process	An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.
GO:0001807	regulation of type IV hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.
GO:0001808	negative regulation of type IV hypersensitivity	biological_process	Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.
GO:0001809	positive regulation of type IV hypersensitivity	biological_process	Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.
GO:0001810	regulation of type I hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.
GO:0001811	negative regulation of type I hypersensitivity	biological_process	Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.
GO:0001812	positive regulation of type I hypersensitivity	biological_process	Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.
GO:0001813	regulation of antibody-dependent cellular cytotoxicity	biological_process	Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.
GO:0001814	negative regulation of antibody-dependent cellular cytotoxicity	biological_process	Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.
GO:0001815	positive regulation of antibody-dependent cellular cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.
GO:0001816	cytokine production	biological_process	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0001817	regulation of cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of production of a cytokine.
GO:0001818	negative regulation of cytokine production	biological_process	Any process that stops, prevents, or reduces the rate of production of a cytokine.
GO:0001819	positive regulation of cytokine production	biological_process	Any process that activates or increases the frequency, rate or extent of production of a cytokine.
GO:0001820	serotonin secretion	biological_process	The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.
GO:0001821	histamine secretion	biological_process	The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.
GO:0001822	kidney development	biological_process	The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
GO:0001823	mesonephros development	biological_process	The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.
GO:0001824	blastocyst development	biological_process	The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
GO:0001825	blastocyst formation	biological_process	The initial formation of a blastocyst from a solid ball of cells known as a morula.
GO:0001826	inner cell mass cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.
GO:0001827	inner cell mass cell fate commitment	biological_process	The cell fate commitment of precursor cells that will become inner cell mass cells.
GO:0001828	inner cell mass cellular morphogenesis	biological_process	The morphogenesis of cells in the inner cell mass.
GO:0001829	trophectodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.
GO:0001830	trophectodermal cell fate commitment	biological_process	The cell fate commitment of precursor cells that will become trophectoderm cells.
GO:0001831	trophectodermal cellular morphogenesis	biological_process	The morphogenesis of trophectoderm cells.
GO:0001832	blastocyst growth	biological_process	An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.
GO:0001833	inner cell mass cell proliferation	biological_process	The proliferation of cells in the inner cell mass.
GO:0001834	trophectodermal cell proliferation	biological_process	The proliferation of cells in the trophectoderm.
GO:0001835	blastocyst hatching	biological_process	The hatching of the cellular blastocyst from the zona pellucida.
GO:0001836	release of cytochrome c from mitochondria	biological_process	The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
GO:0001837	epithelial to mesenchymal transition	biological_process	A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0001838	embryonic epithelial tube formation	biological_process	The morphogenesis of an embryonic epithelium into a tube-shaped structure.
GO:0001839	neural plate morphogenesis	biological_process	The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.
GO:0001840	neural plate development	biological_process	The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
GO:0001841	neural tube formation	biological_process	The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
GO:0001842	neural fold formation	biological_process	The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.
GO:0001843	neural tube closure	biological_process	The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	biological_process	The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.
GO:0001845	phagolysosome assembly	biological_process	The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.
GO:0001846	opsonin binding	molecular_function	Binding to an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.
GO:0001847	opsonin receptor activity	molecular_function	Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001848	complement binding	molecular_function	Binding to a component or product of the complement cascade.
GO:0001849	complement component C1q complex binding	molecular_function	Binding to a C1q complex, a component of the classical complement cascade.
GO:0001850	complement component C3a binding	molecular_function	Binding to a C3a product of the complement cascade.
GO:0001851	complement component C3b binding	molecular_function	Binding to a C3b product of the complement cascade.
GO:0001852	complement component iC3b binding	molecular_function	Binding to a iC3b product of the complement cascade.
GO:0001853	complement component C3dg binding	molecular_function	Binding to a C3dg product of the complement cascade.
GO:0001854	complement component C3d binding	molecular_function	Binding to a C3d product of the complement cascade.
GO:0001855	complement component C4b binding	molecular_function	Binding to a C4b product of the classical complement cascade.
GO:0001856	complement component C5a binding	molecular_function	Binding to a C5a product of the complement cascade.
GO:0001857	complement component C1q receptor activity	molecular_function	Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001858	complement component iC3b receptor activity	molecular_function	Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001859	complement component C3dg receptor activity	molecular_function	Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001860	complement component C3d receptor activity	molecular_function	Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001861	complement component C4b receptor activity	molecular_function	Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001862	collectin binding	molecular_function	Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
GO:0001863	collectin receptor activity	molecular_function	Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0001864	pentraxin binding	molecular_function	Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.
GO:0001865	NK T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a NK T cell.
GO:0001866	NK T cell proliferation	biological_process	The expansion of a NK T cell population by cell division.
GO:0001867	complement activation, lectin pathway	biological_process	Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
GO:0001868	regulation of complement activation, lectin pathway	biological_process	Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.
GO:0001869	negative regulation of complement activation, lectin pathway	biological_process	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.
GO:0001870	positive regulation of complement activation, lectin pathway	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.
GO:0001872	(1->3)-beta-D-glucan binding	molecular_function	Binding to a (1->3)-beta-D-glucan.
GO:0001873	polysaccharide immune receptor activity	molecular_function	Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0001874	(1->3)-beta-D-glucan immune receptor activity	molecular_function	Combining with (1->3)-beta-D-glucans to initiate an innate immune response.
GO:0001875	lipopolysaccharide immune receptor activity	molecular_function	Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
GO:0001876	lipoarabinomannan binding	molecular_function	Binding to lipoarabinomannan.
GO:0001877	lipoarabinomannan immune receptor activity	molecular_function	Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.
GO:0001878	response to yeast	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.
GO:0001879	detection of yeast	biological_process	The series of events in which a stimulus from a yeast is received and converted into a molecular signal.
GO:0001880	Mullerian duct regression	biological_process	The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
GO:0001881	receptor recycling	biological_process	The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.
GO:0001882	nucleoside binding	molecular_function	Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.
GO:0001883	purine nucleoside binding	molecular_function	Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.
GO:0001884	pyrimidine nucleoside binding	molecular_function	Binding to a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.
GO:0001885	endothelial cell development	biological_process	The progression of an endothelial cell over time, from its formation to the mature structure.
GO:0001886	endothelial cell morphogenesis	biological_process	The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
GO:0001887	selenium compound metabolic process	biological_process	The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.
GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.
GO:0001889	liver development	biological_process	The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
GO:0001890	placenta development	biological_process	The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
GO:0001891	phagocytic cup	cellular_component	An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.
GO:0001892	embryonic placenta development	biological_process	The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
GO:0001893	maternal placenta development	biological_process	Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
GO:0001894	tissue homeostasis	biological_process	A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.
GO:0001895	retina homeostasis	biological_process	A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.
GO:0001896	autolysis	biological_process	A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.
GO:0001897	cytolysis by symbiont of host cells	biological_process	The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0001905	activation of membrane attack complex	biological_process	The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.
GO:0001906	cell killing	biological_process	Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0001907	killing by symbiont of host cells	biological_process	Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0001909	leukocyte mediated cytotoxicity	biological_process	The directed killing of a target cell by a leukocyte.
GO:0001910	regulation of leukocyte mediated cytotoxicity	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	biological_process	Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.
GO:0001913	T cell mediated cytotoxicity	biological_process	The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
GO:0001914	regulation of T cell mediated cytotoxicity	biological_process	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.
GO:0001915	negative regulation of T cell mediated cytotoxicity	biological_process	Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.
GO:0001916	positive regulation of T cell mediated cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.
GO:0001917	photoreceptor inner segment	cellular_component	The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
GO:0001918	farnesylated protein binding	molecular_function	Binding to a farnesylated protein.
GO:0001919	regulation of receptor recycling	biological_process	Any process that modulates the frequency, rate, or extent of receptor recycling.
GO:0001920	negative regulation of receptor recycling	biological_process	Any process that stops, prevents, or reduces the rate of receptor recycling.
GO:0001921	positive regulation of receptor recycling	biological_process	Any process that activates or increases the frequency, rate or extent of receptor recycling.
GO:0001922	B-1 B cell homeostasis	biological_process	The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
GO:0001923	B-1 B cell differentiation	biological_process	The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
GO:0001924	regulation of B-1 B cell differentiation	biological_process	Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
GO:0001925	negative regulation of B-1 B cell differentiation	biological_process	Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.
GO:0001926	positive regulation of B-1 B cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.
GO:0001927	exocyst assembly	biological_process	The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.
GO:0001928	regulation of exocyst assembly	biological_process	Any process that modulates the frequency, rate or extent of exocyst assembly.
GO:0001929	negative regulation of exocyst assembly	biological_process	Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.
GO:0001930	positive regulation of exocyst assembly	biological_process	Any process that increases the rate or extent of exocyst assembly.
GO:0001931	uropod	cellular_component	A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
GO:0001932	regulation of protein phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
GO:0001933	negative regulation of protein phosphorylation	biological_process	Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
GO:0001934	positive regulation of protein phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
GO:0001935	endothelial cell proliferation	biological_process	The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
GO:0001936	regulation of endothelial cell proliferation	biological_process	Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.
GO:0001937	negative regulation of endothelial cell proliferation	biological_process	Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
GO:0001938	positive regulation of endothelial cell proliferation	biological_process	Any process that activates or increases the rate or extent of endothelial cell proliferation.
GO:0001939	female pronucleus	cellular_component	The pronucleus originating from the ovum that is being fertilized.
GO:0001940	male pronucleus	cellular_component	The pronucleus originating from the spermatozoa that was involved in fertilization.
GO:0001941	postsynaptic membrane organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
GO:0001942	hair follicle development	biological_process	The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
GO:0001944	vasculature development	biological_process	The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
GO:0001945	lymph vessel development	biological_process	The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
GO:0001946	lymphangiogenesis	biological_process	Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
GO:0001947	heart looping	biological_process	The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
GO:0001949	sebaceous gland cell differentiation	biological_process	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
GO:0001951	intestinal D-glucose absorption	biological_process	Uptake of D-glucose into the blood by absorption from the small intestine.
GO:0001952	regulation of cell-matrix adhesion	biological_process	Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
GO:0001953	negative regulation of cell-matrix adhesion	biological_process	Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
GO:0001954	positive regulation of cell-matrix adhesion	biological_process	Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
GO:0001955	blood vessel maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.
GO:0001956	positive regulation of neurotransmitter secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.
GO:0001957	intramembranous ossification	biological_process	Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
GO:0001958	endochondral ossification	biological_process	Replacement ossification wherein bone tissue replaces cartilage.
GO:0001959	regulation of cytokine-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
GO:0001960	negative regulation of cytokine-mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
GO:0001961	positive regulation of cytokine-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
GO:0001962	alpha-1,3-galactosyltransferase activity	molecular_function	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
GO:0001963	synaptic transmission, dopaminergic	biological_process	The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0001964	startle response	biological_process	An action or movement due to the application of a sudden unexpected stimulus.
GO:0001965	G-protein alpha-subunit binding	molecular_function	Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
GO:0001966	thigmotaxis	biological_process	The directed movement of an animal in response to touch.
GO:0001967	suckling behavior	biological_process	Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
GO:0001968	fibronectin binding	molecular_function	Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
GO:0001969	regulation of activation of membrane attack complex	biological_process	Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
GO:0001970	positive regulation of activation of membrane attack complex	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
GO:0001971	negative regulation of activation of membrane attack complex	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
GO:0001972	retinoic acid binding	molecular_function	Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
GO:0001973	G protein-coupled adenosine receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
GO:0001974	blood vessel remodeling	biological_process	The reorganization or renovation of existing blood vessels.
GO:0001975	response to amphetamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	biological_process	The regulation of blood pressure mediated by detection of stimuli and a neurological response.
GO:0001977	renal system process involved in regulation of blood volume	biological_process	A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	biological_process	The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.
GO:0001979	regulation of systemic arterial blood pressure by chemoreceptor signaling	biological_process	The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	biological_process	The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.
GO:0001981	baroreceptor detection of arterial stretch	biological_process	The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	biological_process	The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.
GO:0001983	baroreceptor response to increased systemic arterial blood pressure	biological_process	The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.
GO:0001984	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure	biological_process	An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	biological_process	Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.
GO:0001987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	biological_process	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.
GO:0001989	positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure	biological_process	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure.
GO:0001990	regulation of systemic arterial blood pressure by hormone	biological_process	The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	biological_process	The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.
GO:0001992	regulation of systemic arterial blood pressure by vasopressin	biological_process	The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	biological_process	The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	biological_process	A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.
GO:0001995	norepinephrine-epinephrine catabolic process in blood stream	biological_process	The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	biological_process	The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.
GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine	biological_process	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.
GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	biological_process	The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.
GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	biological_process	The physiological response of the kidneys to a decrease in blood flow.
GO:0002000	detection of renal blood flow	biological_process	The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.
GO:0002001	renin secretion into blood stream	biological_process	The regulated release of renin into the blood stream by juxtoglomerular cells.
GO:0002002	regulation of angiotensin levels in blood	biological_process	The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.
GO:0002003	angiotensin maturation	biological_process	The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.
GO:0002004	secretion of vasopressin involved in fast regulation of systemic arterial blood pressure	biological_process	The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.
GO:0002006	vasoconstriction by vasopressin involved in systemic arterial blood pressure control	biological_process	The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.
GO:0002007	detection of hypoxic conditions in blood by chemoreceptor signaling	biological_process	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
GO:0002008	excitation of vasomotor center by chemoreceptor signaling	biological_process	The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
GO:0002009	morphogenesis of an epithelium	biological_process	The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
GO:0002010	excitation of vasomotor center by baroreceptor signaling	biological_process	The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.
GO:0002011	morphogenesis of an epithelial sheet	biological_process	The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
GO:0002012	vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure	biological_process	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
GO:0002013	detection of carbon dioxide by vasomotor center	biological_process	The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.
GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure	biological_process	The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.
GO:0002015	regulation of systemic arterial blood pressure by atrial baroreceptor feedback	biological_process	A process that controls blood pressure by sensing the amount of stretch occurring in the atria.
GO:0002016	regulation of blood volume by renin-angiotensin	biological_process	The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.
GO:0002017	regulation of blood volume by renal aldosterone	biological_process	The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.
GO:0002018	renin-angiotensin regulation of aldosterone production	biological_process	The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.
GO:0002019	regulation of renal output by angiotensin	biological_process	The process in which angiotensin directly modulates the rate of urine output by the kidney.
GO:0002020	protease binding	molecular_function	Binding to a protease or a peptidase.
GO:0002021	response to dietary excess	biological_process	The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
GO:0002022	detection of dietary excess	biological_process	The neurological process in which the brain senses excessive caloric intake.
GO:0002023	reduction of food intake in response to dietary excess	biological_process	An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.
GO:0002024	diet induced thermogenesis	biological_process	The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signaling in the sympathetic nervous system.
GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	biological_process	A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.
GO:0002026	regulation of the force of heart contraction	biological_process	Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
GO:0002027	regulation of heart rate	biological_process	Any process that modulates the frequency or rate of heart contraction.
GO:0002028	regulation of sodium ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	biological_process	The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.
GO:0002030	inhibitory G protein-coupled receptor phosphorylation	biological_process	The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.
GO:0002031	G protein-coupled receptor internalization	biological_process	The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.
GO:0002032	desensitization of G protein-coupled receptor signaling pathway by arrestin	biological_process	The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.
GO:0002033	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	biological_process	The process that increases the diameter of a blood vessel via the renin-angiotensin system.
GO:0002034	maintenance of blood vessel diameter homeostasis by renin-angiotensin	biological_process	The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.
GO:0002035	brain renin-angiotensin system	biological_process	The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.
GO:0002036	regulation of L-glutamate import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.
GO:0002037	negative regulation of L-glutamate import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.
GO:0002038	positive regulation of L-glutamate import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.
GO:0002039	p53 binding	molecular_function	Binding to one of the p53 family of proteins.
GO:0002040	sprouting angiogenesis	biological_process	The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
GO:0002041	intussusceptive angiogenesis	biological_process	The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.
GO:0002042	cell migration involved in sprouting angiogenesis	biological_process	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	biological_process	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.
GO:0002044	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	biological_process	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.
GO:0002045	regulation of cell adhesion involved in intussusceptive angiogenesis	biological_process	The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.
GO:0002046	opsin binding	molecular_function	Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
GO:0002047	phenazine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.
GO:0002048	pyoverdine metabolic process	biological_process	The chemical reactions and pathways involving the siderochrome pyoverdine.
GO:0002049	pyoverdine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
GO:0002050	pyoverdine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.
GO:0002051	osteoblast fate commitment	biological_process	The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
GO:0002052	positive regulation of neuroblast proliferation	biological_process	Any process that activates or increases the rate of neuroblast proliferation.
GO:0002053	positive regulation of mesenchymal cell proliferation	biological_process	The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.
GO:0002054	nucleobase binding	molecular_function	Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.
GO:0002055	adenine binding	molecular_function	Binding to adenine, a purine base.
GO:0002056	cytosine binding	molecular_function	Binding to cytosine.
GO:0002057	guanine binding	molecular_function	Binding to guanine.
GO:0002058	uracil binding	molecular_function	Binding to uracil.
GO:0002059	thymine binding	molecular_function	Binding to thymine.
GO:0002060	purine nucleobase binding	molecular_function	Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.
GO:0002061	pyrimidine nucleobase binding	molecular_function	Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.
GO:0002062	chondrocyte differentiation	biological_process	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
GO:0002063	chondrocyte development	biological_process	The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
GO:0002064	epithelial cell development	biological_process	The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
GO:0002065	columnar/cuboidal epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
GO:0002066	columnar/cuboidal epithelial cell development	biological_process	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
GO:0002067	glandular epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
GO:0002068	glandular epithelial cell development	biological_process	The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
GO:0002069	columnar/cuboidal epithelial cell maturation	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
GO:0002070	epithelial cell maturation	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
GO:0002071	glandular epithelial cell maturation	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
GO:0002072	optic cup morphogenesis involved in camera-type eye development	biological_process	The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.
GO:0002074	extraocular skeletal muscle development	biological_process	The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
GO:0002075	somitomeric trunk muscle development	biological_process	The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
GO:0002076	osteoblast development	biological_process	The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.
GO:0002077	acrosome matrix dispersal	biological_process	The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.
GO:0002078	membrane fusion involved in acrosome reaction	biological_process	The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.
GO:0002079	inner acrosomal membrane	cellular_component	The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
GO:0002080	acrosomal membrane	cellular_component	The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
GO:0002081	outer acrosomal membrane	cellular_component	The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.
GO:0002082	regulation of oxidative phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
GO:0002083	4-hydroxybenzoate decaprenyltransferase activity	molecular_function	Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.
GO:0002084	protein depalmitoylation	biological_process	The removal of palymitoyl groups from a lipoprotein.
GO:0002085	inhibition of neuroepithelial cell differentiation	biological_process	Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.
GO:0002086	diaphragm contraction	biological_process	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.
GO:0002087	regulation of respiratory gaseous exchange by nervous system process	biological_process	A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
GO:0002088	lens development in camera-type eye	biological_process	The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
GO:0002089	lens morphogenesis in camera-type eye	biological_process	The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
GO:0002090	regulation of receptor internalization	biological_process	Any process that modulates the frequency, rate or extent of receptor internalization.
GO:0002091	negative regulation of receptor internalization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
GO:0002092	positive regulation of receptor internalization	biological_process	Any process that activates or increases the frequency, rate or extent of receptor internalization.
GO:0002093	auditory receptor cell morphogenesis	biological_process	Any process that alters the size or shape of an auditory receptor cell.
GO:0002094	polyprenyltransferase activity	molecular_function	Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).
GO:0002095	caveolar macromolecular signaling complex	cellular_component	A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).
GO:0002096	polkadots	cellular_component	A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
GO:0002097	tRNA wobble base modification	biological_process	The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.
GO:0002098	tRNA wobble uridine modification	biological_process	The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
GO:0002099	tRNA wobble guanine modification	biological_process	The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
GO:0002100	tRNA wobble adenosine to inosine editing	biological_process	The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine.
GO:0002101	tRNA wobble cytosine modification	biological_process	The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified.
GO:0002102	podosome	cellular_component	An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
GO:0002103	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0002104	endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0002105	endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0002106	endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	biological_process	Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
GO:0002107	generation of mature 3'-end of 5S rRNA generated by RNA polymerase III	biological_process	The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.
GO:0002108	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	biological_process	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
GO:0002109	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	biological_process	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
GO:0002110	cotranscriptional mitochondrial rRNA nucleotide insertion	biological_process	The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.
GO:0002111	BRCA2-BRAF35 complex	cellular_component	A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.
GO:0002112	interleukin-33 receptor binding	molecular_function	Binding to an interleukin-33 receptor.
GO:0002113	interleukin-33 binding	molecular_function	Binding to interleukin-33.
GO:0002114	interleukin-33 receptor activity	molecular_function	Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0002115	store-operated calcium entry	biological_process	A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.
GO:0002116	semaphorin receptor complex	cellular_component	A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
GO:0002117	amphibian larval development	biological_process	The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.
GO:0002118	aggressive behavior	biological_process	A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.
GO:0002119	nematode larval development	biological_process	The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
GO:0002121	inter-male aggressive behavior	biological_process	Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.
GO:0002122	fear-induced aggressive behavior	biological_process	Aggressive behavior associated with attempts to flee from a threat.
GO:0002123	irritable aggressive behavior	biological_process	Aggressive behavior induced by frustration and directed against an available target.
GO:0002124	territorial aggressive behavior	biological_process	Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.
GO:0002125	maternal aggressive behavior	biological_process	Aggressive behavior of a female to protect her offspring from a threat.
GO:0002126	instrumental aggressive behavior	biological_process	Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.
GO:0002127	tRNA wobble base cytosine methylation	biological_process	The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.
GO:0002128	tRNA nucleoside ribose methylation	biological_process	The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.
GO:0002129	wobble position guanine ribose methylation	biological_process	The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
GO:0002130	wobble position ribose methylation	biological_process	The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.
GO:0002131	wobble position cytosine ribose methylation	biological_process	The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
GO:0002132	wobble position uridine ribose methylation	biological_process	The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
GO:0002133	polycystin complex	cellular_component	A stable heterodimeric complex composed of polycystin-1 and polycystin-2.
GO:0002134	UTP binding	molecular_function	Binding to UTP, uridine 5'-triphosphate.
GO:0002135	CTP binding	molecular_function	Binding to CTP, cytidine 5'-triphosphate.
GO:0002136	tRNA wobble base lysidine biosynthesis	biological_process	The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.
GO:0002138	retinoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.
GO:0002139	stereocilia coupling link	cellular_component	A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.
GO:0002140	stereocilia tip link	cellular_component	A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.
GO:0002141	stereocilia ankle link	cellular_component	A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.
GO:0002142	stereocilia ankle link complex	cellular_component	A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.
GO:0002143	tRNA wobble position uridine thiolation	biological_process	The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
GO:0002144	cytosolic tRNA wobble base thiouridylase complex	cellular_component	A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.
GO:0002145	4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity	molecular_function	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H+.
GO:0002148	hypochlorous acid metabolic process	biological_process	The chemical reactions and pathways involving hypochlorous acid.
GO:0002149	hypochlorous acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hypochlorous acid.
GO:0002150	hypochlorous acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.
GO:0002151	G-quadruplex RNA binding	molecular_function	Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
GO:0002152	bile acid conjugation	biological_process	The process in which bile acids are covalently linked to taurine or glycine.
GO:0002153	steroid receptor RNA activator RNA binding	molecular_function	Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.
GO:0002154	thyroid hormone mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of a thyroid hormone.
GO:0002155	regulation of thyroid hormone mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.
GO:0002156	negative regulation of thyroid hormone mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.
GO:0002157	positive regulation of thyroid hormone mediated signaling pathway	biological_process	Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.
GO:0002158	osteoclast proliferation	biological_process	The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.
GO:0002159	desmosome assembly	biological_process	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
GO:0002160	desmosome maintenance	biological_process	The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
GO:0002161	aminoacyl-tRNA editing activity	molecular_function	The hydrolysis of an incorrectly aminoacylated tRNA.
GO:0002162	dystroglycan binding	molecular_function	Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).
GO:0002164	larval development	biological_process	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.
GO:0002165	instar larval or pupal development	biological_process	The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.
GO:0002167	VRK3/VHR/ERK complex	cellular_component	A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.
GO:0002168	instar larval development	biological_process	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.
GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial	cellular_component	A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.
GO:0002170	high-affinity IgA receptor activity	molecular_function	Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0002171	low-affinity IgA receptor activity	molecular_function	Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0002172	high-affinity IgM receptor activity	molecular_function	Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0002173	low-affinity IgM receptor activity	molecular_function	Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0002174	mammary stem cell proliferation	biological_process	The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.
GO:0002175	protein localization to paranode region of axon	biological_process	A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.
GO:0002176	male germ cell proliferation	biological_process	The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.
GO:0002177	manchette	cellular_component	A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.
GO:0002178	palmitoyltransferase complex	cellular_component	A protein complex with palmitoyltransferase activity.
GO:0002179	homodimeric serine palmitoyltransferase complex	cellular_component	A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.
GO:0002180	5-lipoxygenase complex	cellular_component	An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.
GO:0002181	cytoplasmic translation	biological_process	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
GO:0002182	cytoplasmic translational elongation	biological_process	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
GO:0002183	cytoplasmic translational initiation	biological_process	The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GO:0002184	cytoplasmic translational termination	biological_process	The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
GO:0002185	creatine kinase complex	cellular_component	A protein complex having creatine kinase activity.
GO:0002186	cytosolic creatine kinase complex	cellular_component	A dimeric protein complex having creatine kinase activity.
GO:0002187	mitochondrial creatine kinase complex	cellular_component	An octomeric protein complex having creatine kinase activity.
GO:0002188	translation reinitiation	biological_process	A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.
GO:0002189	ribose phosphate diphosphokinase complex	cellular_component	A protein complex having ribose phosphate diphosphokinase activity.
GO:0002190	cap-independent translational initiation	biological_process	The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.
GO:0002191	cap-dependent translational initiation	biological_process	The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.
GO:0002192	IRES-dependent translational initiation of linear mRNA	biological_process	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.
GO:0002193	MAML1-RBP-Jkappa- ICN1 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0002194	hepatocyte cell migration	biological_process	The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.
GO:0002195	2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis	biological_process	The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.
GO:0002196	Ser-tRNA(Ala) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
GO:0002197	xanthine dehydrogenase complex	cellular_component	A homodimeric protein complex having xanthine dehydrogenase activity.
GO:0002199	zona pellucida receptor complex	cellular_component	A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.
GO:0002200	somatic diversification of immune receptors	biological_process	The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
GO:0002201	somatic diversification of DSCAM-based immune receptors	biological_process	The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.
GO:0002202	somatic diversification of variable lymphocyte receptors of jawless fish	biological_process	The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.
GO:0002203	proteolysis by cytosolic proteases associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	biological_process	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.
GO:0002205	somatic hypermutation of immunoglobulin genes involved in immune response	biological_process	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.
GO:0002206	gene conversion of immunoglobulin genes	biological_process	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.
GO:0002207	gene conversion of immunoglobulin genes involved in immune response	biological_process	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.
GO:0002208	somatic diversification of immunoglobulins involved in immune response	biological_process	The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.
GO:0002209	behavioral defense response	biological_process	A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
GO:0002210	behavioral response to wounding	biological_process	A behavioral response resulting from wounding.
GO:0002211	behavioral defense response to insect	biological_process	A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
GO:0002212	behavioral defense response to nematode	biological_process	A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
GO:0002213	defense response to insect	biological_process	A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.
GO:0002215	defense response to nematode	biological_process	A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0002218	activation of innate immune response	biological_process	Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
GO:0002220	innate immune response activating cell surface receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a cell surface receptor that leads to the activation of an innate immune response.
GO:0002221	pattern recognition receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
GO:0002222	stimulatory killer cell immunoglobulin-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a killer cell immunoglobulin-like receptor capable of cellular activation.
GO:0002223	stimulatory C-type lectin receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of C-type lectin to its receptor on the surface of a target cell, and resulting in cellular activation.
GO:0002224	toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0002225	positive regulation of antimicrobial peptide production	biological_process	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.
GO:0002227	innate immune response in mucosa	biological_process	Any process of the innate immune response that takes place in the mucosal tissues.
GO:0002228	natural killer cell mediated immunity	biological_process	The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
GO:0002229	defense response to oomycetes	biological_process	Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
GO:0002230	positive regulation of defense response to virus by host	biological_process	Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
GO:0002231	detection of oomycetes	biological_process	The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.
GO:0002232	leukocyte chemotaxis involved in inflammatory response	biological_process	The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
GO:0002233	leukocyte chemotaxis involved in immune response	biological_process	The movement of an immune cell in response to an external stimulus a part of an immune response.
GO:0002234	detection of endoplasmic reticulum overloading	biological_process	The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.
GO:0002235	detection of unfolded protein	biological_process	The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.
GO:0002236	detection of misfolded protein	biological_process	The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.
GO:0002237	response to molecule of bacterial origin	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
GO:0002238	response to molecule of fungal origin	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
GO:0002239	response to oomycetes	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.
GO:0002240	response to molecule of oomycetes origin	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.
GO:0002241	response to parasitic plant	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.
GO:0002242	defense response to parasitic plant	biological_process	Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.
GO:0002243	detection of parasitic plant	biological_process	The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.
GO:0002244	hematopoietic progenitor cell differentiation	biological_process	The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
GO:0002246	wound healing involved in inflammatory response	biological_process	The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.
GO:0002247	clearance of damaged tissue involved in inflammatory response wound healing	biological_process	The series of events leading to removal of necrotic debris that contribute to an inflammatory response.
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	biological_process	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared, as part of an inflammatory response.
GO:0002249	lymphocyte anergy	biological_process	Any process contributing to lymphocyte anergy, a state of functional inactivation.
GO:0002250	adaptive immune response	biological_process	An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GO:0002251	organ or tissue specific immune response	biological_process	An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.
GO:0002252	immune effector process	biological_process	Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.
GO:0002253	activation of immune response	biological_process	Any process that initiates an immune response.
GO:0002254	kinin cascade	biological_process	A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
GO:0002255	tissue kallikrein-kinin cascade	biological_process	A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
GO:0002256	regulation of kinin cascade	biological_process	Any process that modulates the frequency, rate, or extent of the kinin cascade.
GO:0002257	negative regulation of kinin cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.
GO:0002258	positive regulation of kinin cascade	biological_process	Any process that activates or increases the frequency, rate, or extent of the kinin cascade.
GO:0002259	endothelial cell activation within high endothelial venule involved in immune response	biological_process	A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002260	lymphocyte homeostasis	biological_process	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0002261	mucosal lymphocyte homeostasis	biological_process	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.
GO:0002262	myeloid cell homeostasis	biological_process	The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0002263	cell activation involved in immune response	biological_process	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002264	endothelial cell activation involved in immune response	biological_process	A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002265	astrocyte activation involved in immune response	biological_process	A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002266	follicular dendritic cell activation	biological_process	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0002267	follicular dendritic cell activation involved in immune response	biological_process	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002268	follicular dendritic cell differentiation	biological_process	The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.
GO:0002269	leukocyte activation involved in inflammatory response	biological_process	A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.
GO:0002270	plasmacytoid dendritic cell activation	biological_process	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0002271	plasmacytoid dendritic cell activation involved in immune response	biological_process	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002272	plasmacytoid dendritic cell differentiation involved in immune response	biological_process	The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.
GO:0002273	plasmacytoid dendritic cell differentiation	biological_process	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.
GO:0002274	myeloid leukocyte activation	biological_process	A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0002275	myeloid cell activation involved in immune response	biological_process	A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
GO:0002276	basophil activation involved in immune response	biological_process	A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
GO:0002277	myeloid dendritic cell activation involved in immune response	biological_process	The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002278	eosinophil activation involved in immune response	biological_process	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002279	mast cell activation involved in immune response	biological_process	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
GO:0002280	monocyte activation involved in immune response	biological_process	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002281	macrophage activation involved in immune response	biological_process	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002282	microglial cell activation involved in immune response	biological_process	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002283	neutrophil activation involved in immune response	biological_process	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002284	myeloid dendritic cell differentiation involved in immune response	biological_process	The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.
GO:0002285	lymphocyte activation involved in immune response	biological_process	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002286	T cell activation involved in immune response	biological_process	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
GO:0002287	alpha-beta T cell activation involved in immune response	biological_process	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
GO:0002288	NK T cell activation involved in immune response	biological_process	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
GO:0002289	NK T cell proliferation involved in immune response	biological_process	The expansion of a NK T cell population by cell division as part of an immune response.
GO:0002290	gamma-delta T cell activation involved in immune response	biological_process	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological_process	The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.
GO:0002292	T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
GO:0002293	alpha-beta T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
GO:0002295	T-helper cell lineage commitment	biological_process	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.
GO:0002296	T-helper 1 cell lineage commitment	biological_process	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
GO:0002297	T-helper 2 cell lineage commitment	biological_process	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.
GO:0002298	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
GO:0002299	alpha-beta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002300	CD8-positive, alpha-beta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002301	CD4-positive, alpha-beta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
GO:0002303	gamma-delta T cell differentiation involved in immune response	biological_process	The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
GO:0002304	gamma-delta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002305	CD8-positive, gamma-delta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002306	CD4-positive gamma-delta intraepithelial T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
GO:0002307	CD8-positive, alpha-beta regulatory T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
GO:0002308	CD8-positive, alpha-beta cytotoxic T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
GO:0002309	T cell proliferation involved in immune response	biological_process	The expansion of a T cell population by cell division as part of an immune response.
GO:0002310	alpha-beta T cell proliferation involved in immune response	biological_process	The expansion of an alpha-beta T cell population by cell division as part of an immune response.
GO:0002311	gamma-delta T cell proliferation involved in immune response	biological_process	The expansion of a gamma-delta T cell population by cell division as part of an immune response.
GO:0002312	B cell activation involved in immune response	biological_process	The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0002313	mature B cell differentiation involved in immune response	biological_process	The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.
GO:0002314	germinal center B cell differentiation	biological_process	The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).
GO:0002315	marginal zone B cell differentiation	biological_process	The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).
GO:0002316	follicular B cell differentiation	biological_process	The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
GO:0002317	plasma cell differentiation	biological_process	The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
GO:0002318	myeloid progenitor cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
GO:0002319	memory B cell differentiation	biological_process	The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
GO:0002320	lymphoid progenitor cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.
GO:0002321	natural killer cell progenitor differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.
GO:0002322	B cell proliferation involved in immune response	biological_process	The expansion of a B cell population by cell division following B cell activation during an immune response.
GO:0002323	natural killer cell activation involved in immune response	biological_process	The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002324	natural killer cell proliferation involved in immune response	biological_process	The expansion of a natural killer cell population by cell division as part of an immune response.
GO:0002325	natural killer cell differentiation involved in immune response	biological_process	The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.
GO:0002326	B cell lineage commitment	biological_process	The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.
GO:0002327	immature B cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of an immature B cell.
GO:0002328	pro-B cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
GO:0002329	pre-B cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
GO:0002330	pre-B cell receptor expression	biological_process	The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.
GO:0002331	pre-B cell allelic exclusion	biological_process	Expression of a single heavy chain allele during pre-B cell differentiation.
GO:0002332	transitional stage B cell differentiation	biological_process	The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.
GO:0002333	transitional one stage B cell differentiation	biological_process	The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.
GO:0002334	transitional two stage B cell differentiation	biological_process	The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.
GO:0002335	mature B cell differentiation	biological_process	The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.
GO:0002336	B-1 B cell lineage commitment	biological_process	The process in which an immature B cell becomes committed to become a B-1 B cell.
GO:0002337	B-1a B cell differentiation	biological_process	The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
GO:0002338	B-1b B cell differentiation	biological_process	The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
GO:0002339	B cell selection	biological_process	The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
GO:0002340	central B cell selection	biological_process	Any B cell selection process that occurs in the bone marrow.
GO:0002341	central B cell anergy	biological_process	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.
GO:0002342	central B cell deletion	biological_process	The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.
GO:0002343	peripheral B cell selection	biological_process	Any B cell selection process that occurs in the periphery.
GO:0002344	B cell affinity maturation	biological_process	The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.
GO:0002345	peripheral B cell receptor editing	biological_process	The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.
GO:0002346	B cell positive selection	biological_process	Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.
GO:0002347	response to tumor cell	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
GO:0002348	central B cell positive selection	biological_process	Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
GO:0002349	histamine production involved in inflammatory response	biological_process	The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002350	peripheral B cell positive selection	biological_process	Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
GO:0002351	serotonin production involved in inflammatory response	biological_process	The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002352	B cell negative selection	biological_process	Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
GO:0002353	plasma kallikrein-kinin cascade	biological_process	A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
GO:0002354	central B cell negative selection	biological_process	Any process leading to negative selection of B cells in the bone marrow.
GO:0002355	detection of tumor cell	biological_process	The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.
GO:0002356	peripheral B cell negative selection	biological_process	Any process leading to negative selection of B cells in the periphery.
GO:0002357	defense response to tumor cell	biological_process	Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.
GO:0002358	B cell homeostatic proliferation	biological_process	The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
GO:0002359	B-1 B cell proliferation	biological_process	The expansion of a B-1 B cell by cell division. Follows B cell activation.
GO:0002360	T cell lineage commitment	biological_process	The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
GO:0002362	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	biological_process	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
GO:0002363	alpha-beta T cell lineage commitment	biological_process	The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.
GO:0002364	NK T cell lineage commitment	biological_process	The process in which a pro-T cell becomes committed to becoming an NK T cell.
GO:0002365	gamma-delta T cell lineage commitment	biological_process	The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.
GO:0002366	leukocyte activation involved in immune response	biological_process	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
GO:0002367	cytokine production involved in immune response	biological_process	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
GO:0002368	B cell cytokine production	biological_process	Any process that contributes to cytokine production by a B cell.
GO:0002369	T cell cytokine production	biological_process	Any process that contributes to cytokine production by a T cell.
GO:0002370	natural killer cell cytokine production	biological_process	Any process that contributes to cytokine production by a natural killer cell.
GO:0002371	dendritic cell cytokine production	biological_process	Any process that contributes to cytokine production by a dendritic cell.
GO:0002372	myeloid dendritic cell cytokine production	biological_process	Any process that contributes to cytokine production by a myeloid dendritic cell.
GO:0002373	plasmacytoid dendritic cell cytokine production	biological_process	Any process that contributes to cytokine production by a plasmacytoid dendritic cell.
GO:0002376	immune system process	biological_process	Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0002377	immunoglobulin production	biological_process	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	biological_process	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
GO:0002382	regulation of tissue kallikrein-kinin cascade	biological_process	Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
GO:0002383	immune response in brain or nervous system	biological_process	An immune response taking place in the brain or nervous system.
GO:0002384	hepatic immune response	biological_process	An immune response taking place in the liver.
GO:0002385	mucosal immune response	biological_process	An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
GO:0002387	immune response in gut-associated lymphoid tissue	biological_process	Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.
GO:0002388	immune response in Peyer's patch	biological_process	Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.
GO:0002389	tolerance induction in Peyer's patch	biological_process	Tolerance induction taking place in the Peyer's patches.
GO:0002391	platelet activating factor production involved in inflammatory response	biological_process	The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002393	lysosomal enzyme production involved in inflammatory response	biological_process	The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.
GO:0002394	tolerance induction in gut-associated lymphoid tissue	biological_process	Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).
GO:0002395	immune response in nasopharyngeal-associated lymphoid tissue	biological_process	An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.
GO:0002396	MHC protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.
GO:0002397	MHC class I protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0002398	MHC class Ib protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.
GO:0002399	MHC class II protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.
GO:0002400	tolerance induction in nasopharyngeal-associated lymphoid tissue	biological_process	Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT).
GO:0002401	tolerance induction in mucosal-associated lymphoid tissue	biological_process	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).
GO:0002402	B cell tolerance induction in mucosal-associated lymphoid tissue	biological_process	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.
GO:0002403	T cell tolerance induction in mucosal-associated lymphoid tissue	biological_process	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.
GO:0002404	antigen sampling in mucosal-associated lymphoid tissue	biological_process	The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.
GO:0002405	antigen sampling by dendritic cells in mucosal-associated lymphoid tissue	biological_process	The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.
GO:0002406	antigen sampling by M cells in mucosal-associated lymphoid tissue	biological_process	The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
GO:0002407	dendritic cell chemotaxis	biological_process	The movement of a dendritic cell in response to an external stimulus.
GO:0002408	myeloid dendritic cell chemotaxis	biological_process	The movement of a myeloid dendritic cell in response to an external stimulus.
GO:0002409	Langerhans cell chemotaxis	biological_process	The movement of a Langerhans cell in response to an external stimulus.
GO:0002410	plasmacytoid dendritic cell chemotaxis	biological_process	The movement of a plasmacytoid dendritic cell in response to an external stimulus.
GO:0002411	T cell tolerance induction to tumor cell	biological_process	A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.
GO:0002412	antigen transcytosis by M cells in mucosal-associated lymphoid tissue	biological_process	The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.
GO:0002413	tolerance induction to tumor cell	biological_process	A process of tolerance induction which leads to immunological tolerance of a tumor.
GO:0002414	immunoglobulin transcytosis in epithelial cells	biological_process	The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.
GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	biological_process	The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.
GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	biological_process	The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals.
GO:0002417	B cell antigen processing and presentation mediated by B cell receptor uptake of antigen	biological_process	B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.
GO:0002418	immune response to tumor cell	biological_process	An immune system process that functions in the response of an organism to a tumor cell.
GO:0002419	T cell mediated cytotoxicity directed against tumor cell target	biological_process	The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target	biological_process	The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
GO:0002421	B cell antigen processing and presentation following pinocytosis	biological_process	B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
GO:0002423	natural killer cell mediated immune response to tumor cell	biological_process	An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
GO:0002424	T cell mediated immune response to tumor cell	biological_process	An immune response mediated by a T cell triggered in response to the presence of a tumor cell.
GO:0002425	tolerance induction in urogenital tract	biological_process	Tolerance induction taking place in the urogenital tract.
GO:0002426	immunoglobulin production in mucosal tissue	biological_process	The synthesis and release of immunoglobulin in the mucosal tissue.
GO:0002427	mucosal tolerance induction	biological_process	Tolerance induction taking place in the mucosal tissues.
GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
GO:0002429	immune response-activating cell surface receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.
GO:0002430	complement receptor mediated signaling pathway	biological_process	The series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
GO:0002431	Fc receptor mediated stimulatory signaling pathway	biological_process	The series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
GO:0002432	granuloma formation	biological_process	The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	biological_process	An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
GO:0002434	immune complex clearance	biological_process	A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.
GO:0002435	immune complex clearance by erythrocytes	biological_process	The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.
GO:0002436	immune complex clearance by monocytes and macrophages	biological_process	The process of immune complex clearance by monocytes or macrophages.
GO:0002437	inflammatory response to antigenic stimulus	biological_process	An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
GO:0002438	acute inflammatory response to antigenic stimulus	biological_process	An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
GO:0002439	chronic inflammatory response to antigenic stimulus	biological_process	A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.
GO:0002440	production of molecular mediator of immune response	biological_process	The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
GO:0002441	histamine secretion involved in inflammatory response	biological_process	The regulated release of histamine by a cell as part of an inflammatory response.
GO:0002442	serotonin secretion involved in inflammatory response	biological_process	The regulated release of serotonin by a cell as part of an inflammatory response.
GO:0002443	leukocyte mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a leukocyte.
GO:0002444	myeloid leukocyte mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a myeloid leukocyte.
GO:0002445	type II hypersensitivity	biological_process	An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
GO:0002446	neutrophil mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a neutrophil.
GO:0002447	eosinophil mediated immunity	biological_process	Any process involved in the carrying out of an immune response by an eosinophil.
GO:0002448	mast cell mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a mast cell.
GO:0002449	lymphocyte mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002450	B cell antigen processing and presentation	biological_process	The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002451	peripheral B cell tolerance induction	biological_process	Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.
GO:0002452	B cell receptor editing	biological_process	The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
GO:0002453	peripheral B cell anergy	biological_process	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.
GO:0002454	peripheral B cell deletion	biological_process	The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.
GO:0002455	humoral immune response mediated by circulating immunoglobulin	biological_process	An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
GO:0002456	T cell mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a T cell.
GO:0002457	T cell antigen processing and presentation	biological_process	The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002458	peripheral T cell tolerance induction	biological_process	Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.
GO:0002459	adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains	biological_process	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological_process	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
GO:0002461	tolerance induction dependent upon immune response	biological_process	Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.
GO:0002462	tolerance induction to nonself antigen	biological_process	Tolerance induction in response to nonself antigens.
GO:0002463	central tolerance induction to nonself antigen	biological_process	Tolerance induction to nonself antigens in the central lymphoid organs.
GO:0002464	peripheral tolerance induction to nonself antigen	biological_process	Tolerance induction to nonself antigens in the periphery.
GO:0002465	peripheral tolerance induction	biological_process	Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
GO:0002466	peripheral tolerance induction to self antigen	biological_process	Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
GO:0002467	germinal center formation	biological_process	The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
GO:0002468	dendritic cell antigen processing and presentation	biological_process	The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002469	myeloid dendritic cell antigen processing and presentation	biological_process	The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002470	plasmacytoid dendritic cell antigen processing and presentation	biological_process	The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002471	monocyte antigen processing and presentation	biological_process	The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002472	macrophage antigen processing and presentation	biological_process	The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002473	non-professional antigen presenting cell antigen processing and presentation	biological_process	The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0002475	antigen processing and presentation via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002478	antigen processing and presentation of exogenous peptide antigen	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002482	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002483	antigen processing and presentation of endogenous peptide antigen	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
GO:0002487	antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.
GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002490	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002491	antigen processing and presentation of endogenous peptide antigen via MHC class II	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
GO:0002492	peptide antigen assembly with MHC class Ib protein complex	biological_process	The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
GO:0002493	lipid antigen assembly with MHC class Ib protein complex	biological_process	The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.
GO:0002494	lipid antigen transport	biological_process	The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
GO:0002496	proteolysis associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
GO:0002497	proteasomal proteolysis associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.
GO:0002498	proteolysis within endoplasmic reticulum associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
GO:0002499	proteolysis within endosome associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
GO:0002500	proteolysis within lysosome associated with antigen processing and presentation	biological_process	The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
GO:0002501	peptide antigen assembly with MHC protein complex	biological_process	The binding of a peptide to the antigen binding groove of an MHC protein complex.
GO:0002502	peptide antigen assembly with MHC class I protein complex	biological_process	The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0002503	peptide antigen assembly with MHC class II protein complex	biological_process	The binding of a peptide to the antigen binding groove of an MHC class II protein complex.
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological_process	The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
GO:0002505	antigen processing and presentation of polysaccharide antigen via MHC class II	biological_process	The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
GO:0002507	tolerance induction	biological_process	A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
GO:0002508	central tolerance induction	biological_process	Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
GO:0002509	central tolerance induction to self antigen	biological_process	Tolerance induction in the central lymphoid organs directed at self antigens.
GO:0002510	central B cell tolerance induction	biological_process	Tolerance induction of B cells in the bone marrow.
GO:0002511	central B cell receptor editing	biological_process	Receptor editing occurring in B cells in the bone marrow.
GO:0002512	central T cell tolerance induction	biological_process	Tolerance induction of T cells in the thymus.
GO:0002513	tolerance induction to self antigen	biological_process	Tolerance induction directed at self antigens.
GO:0002514	B cell tolerance induction	biological_process	A process involving any mechanism for tolerance induction in B cells.
GO:0002515	B cell anergy	biological_process	Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
GO:0002516	B cell deletion	biological_process	The apoptotic death of B cells which is part of B cell tolerance induction.
GO:0002517	T cell tolerance induction	biological_process	A process involving any mechanism for tolerance induction in T cells.
GO:0002518	lymphocyte chemotaxis across high endothelial venule	biological_process	The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.
GO:0002519	natural killer cell tolerance induction	biological_process	Tolerance induction of natural killer cells.
GO:0002520	immune system development	biological_process	The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0002521	leukocyte differentiation	biological_process	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0002522	leukocyte migration involved in immune response	biological_process	The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.
GO:0002523	leukocyte migration involved in inflammatory response	biological_process	The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
GO:0002524	hypersensitivity	biological_process	An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
GO:0002525	acute inflammatory response to non-antigenic stimulus	biological_process	An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
GO:0002526	acute inflammatory response	biological_process	Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
GO:0002527	vasodilation involved in acute inflammatory response	biological_process	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	biological_process	Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.
GO:0002529	regulation of plasma kallikrein-kinin cascade	biological_process	Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
GO:0002530	regulation of systemic arterial blood pressure involved in acute-phase response	biological_process	Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
GO:0002531	regulation of heart contraction involved in acute-phase response	biological_process	Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
GO:0002532	production of molecular mediator involved in inflammatory response	biological_process	The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0002533	lysosomal enzyme secretion involved in inflammatory response	biological_process	The regulated release of lysosomal enzymes by a cell as part of an inflammatory response.
GO:0002534	cytokine production involved in inflammatory response	biological_process	The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002536	respiratory burst involved in inflammatory response	biological_process	A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
GO:0002537	nitric oxide production involved in inflammatory response	biological_process	The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002538	arachidonic acid metabolite production involved in inflammatory response	biological_process	The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.
GO:0002539	prostaglandin production involved in inflammatory response	biological_process	The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002540	leukotriene production involved in inflammatory response	biological_process	The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
GO:0002541	activation of plasma proteins involved in acute inflammatory response	biological_process	Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
GO:0002542	Factor XII activation	biological_process	Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.
GO:0002543	activation of blood coagulation via clotting cascade	biological_process	Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
GO:0002544	chronic inflammatory response	biological_process	Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.
GO:0002545	chronic inflammatory response to non-antigenic stimulus	biological_process	A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.
GO:0002546	negative regulation of tissue kallikrein-kinin cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
GO:0002547	positive regulation of tissue kallikrein-kinin cascade	biological_process	Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
GO:0002548	monocyte chemotaxis	biological_process	The movement of a monocyte in response to an external stimulus.
GO:0002549	negative regulation of plasma kallikrein-kinin cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
GO:0002550	positive regulation of plasma kallikrein-kinin cascade	biological_process	Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
GO:0002551	mast cell chemotaxis	biological_process	The movement of a mast cell in response to an external stimulus.
GO:0002552	serotonin secretion by mast cell	biological_process	The regulated release of serotonin by a mast cell or group of mast cells.
GO:0002553	histamine secretion by mast cell	biological_process	The regulated release of histamine by a mast cell or group of mast cells.
GO:0002554	serotonin secretion by platelet	biological_process	The regulated release of serotonin by a platelet or group of platelets.
GO:0002555	histamine secretion by platelet	biological_process	The regulated release of histamine by a platelet or group of platelets.
GO:0002556	serotonin secretion by basophil	biological_process	The regulated release of serotonin by a basophil or group of basophils.
GO:0002557	histamine secretion by basophil	biological_process	The regulated release of histamine by a basophil or group of basophils.
GO:0002558	type I hypersensitivity mediated by mast cells	biological_process	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
GO:0002559	type I hypersensitivity mediated by basophils	biological_process	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
GO:0002560	basophil mediated immunity	biological_process	Any process involved in the carrying out of an immune response by a basophil.
GO:0002561	basophil degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	biological_process	The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.
GO:0002563	somatic diversification of immune receptors via alternate splicing	biological_process	The process in which immune receptor genes are diversified through alternate splicing.
GO:0002564	alternate splicing of immunoglobulin genes	biological_process	The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.
GO:0002565	somatic diversification of immune receptors via gene conversion	biological_process	The process in which immune receptor genes are diversified through gene conversion.
GO:0002566	somatic diversification of immune receptors via somatic mutation	biological_process	The process in which immune receptor genes are diversified through somatic mutation.
GO:0002567	somatic diversification of FREP-based immune receptors	biological_process	The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.
GO:0002568	somatic diversification of T cell receptor genes	biological_process	The somatic process that results in the generation of sequence diversity of T cell receptor genes.
GO:0002569	somatic diversification of immune receptors by N region addition	biological_process	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.
GO:0002570	somatic diversification of immunoglobulin genes by N region addition	biological_process	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.
GO:0002571	somatic diversification of T cell receptor genes by N region addition	biological_process	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.
GO:0002572	pro-T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
GO:0002573	myeloid leukocyte differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
GO:0002574	thrombocyte differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
GO:0002575	basophil chemotaxis	biological_process	The movement of a basophil in response to an external stimulus.
GO:0002576	platelet degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
GO:0002577	regulation of antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation.
GO:0002578	negative regulation of antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
GO:0002579	positive regulation of antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.
GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
GO:0002582	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
GO:0002583	regulation of antigen processing and presentation of peptide antigen	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
GO:0002584	negative regulation of antigen processing and presentation of peptide antigen	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
GO:0002585	positive regulation of antigen processing and presentation of peptide antigen	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
GO:0002586	regulation of antigen processing and presentation of peptide antigen via MHC class II	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
GO:0002587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
GO:0002588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
GO:0002590	negative regulation of antigen processing and presentation of peptide antigen via MHC class I	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
GO:0002592	regulation of antigen processing and presentation via MHC class Ib	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
GO:0002593	negative regulation of antigen processing and presentation via MHC class Ib	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
GO:0002594	positive regulation of antigen processing and presentation via MHC class Ib	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
GO:0002595	regulation of antigen processing and presentation of peptide antigen via MHC class Ib	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
GO:0002596	negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
GO:0002597	positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
GO:0002598	regulation of antigen processing and presentation of lipid antigen via MHC class Ib	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
GO:0002599	negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
GO:0002600	positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
GO:0002601	regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	biological_process	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
GO:0002602	negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
GO:0002603	positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	biological_process	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
GO:0002604	regulation of dendritic cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
GO:0002607	regulation of myeloid dendritic cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
GO:0002608	negative regulation of myeloid dendritic cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
GO:0002609	positive regulation of myeloid dendritic cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
GO:0002610	regulation of plasmacytoid dendritic cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
GO:0002611	negative regulation of plasmacytoid dendritic cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
GO:0002612	positive regulation of plasmacytoid dendritic cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
GO:0002613	regulation of monocyte antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.
GO:0002614	negative regulation of monocyte antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.
GO:0002615	positive regulation of monocyte antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.
GO:0002616	regulation of macrophage antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.
GO:0002617	negative regulation of macrophage antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.
GO:0002618	positive regulation of macrophage antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.
GO:0002619	regulation of non-professional antigen presenting cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
GO:0002620	negative regulation of non-professional antigen presenting cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
GO:0002621	positive regulation of non-professional antigen presenting cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
GO:0002622	regulation of B cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.
GO:0002623	negative regulation of B cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.
GO:0002624	positive regulation of B cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.
GO:0002625	regulation of T cell antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.
GO:0002626	negative regulation of T cell antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.
GO:0002627	positive regulation of T cell antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.
GO:0002628	regulation of proteolysis associated with antigen processing and presentation	biological_process	Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
GO:0002629	negative regulation of proteolysis associated with antigen processing and presentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
GO:0002630	positive regulation of proteolysis associated with antigen processing and presentation	biological_process	Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
GO:0002631	regulation of granuloma formation	biological_process	Any process that modulates the frequency, rate, or extent of granuloma formation.
GO:0002632	negative regulation of granuloma formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.
GO:0002633	positive regulation of granuloma formation	biological_process	Any process that activates or increases the frequency, rate, or extent of granuloma formation.
GO:0002634	regulation of germinal center formation	biological_process	Any process that modulates the frequency, rate, or extent of germinal center formation.
GO:0002635	negative regulation of germinal center formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
GO:0002636	positive regulation of germinal center formation	biological_process	Any process that activates or increases the frequency, rate, or extent of germinal center formation.
GO:0002637	regulation of immunoglobulin production	biological_process	Any process that modulates the frequency, rate, or extent of immunoglobulin production.
GO:0002638	negative regulation of immunoglobulin production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
GO:0002639	positive regulation of immunoglobulin production	biological_process	Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
GO:0002643	regulation of tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of tolerance induction.
GO:0002644	negative regulation of tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.
GO:0002645	positive regulation of tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of tolerance induction.
GO:0002646	regulation of central tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of central tolerance induction.
GO:0002647	negative regulation of central tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.
GO:0002648	positive regulation of central tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of central tolerance induction.
GO:0002649	regulation of tolerance induction to self antigen	biological_process	Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.
GO:0002650	negative regulation of tolerance induction to self antigen	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.
GO:0002651	positive regulation of tolerance induction to self antigen	biological_process	Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.
GO:0002652	regulation of tolerance induction dependent upon immune response	biological_process	Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.
GO:0002653	negative regulation of tolerance induction dependent upon immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.
GO:0002654	positive regulation of tolerance induction dependent upon immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.
GO:0002655	regulation of tolerance induction to nonself antigen	biological_process	Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.
GO:0002656	negative regulation of tolerance induction to nonself antigen	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.
GO:0002657	positive regulation of tolerance induction to nonself antigen	biological_process	Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.
GO:0002658	regulation of peripheral tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.
GO:0002659	negative regulation of peripheral tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.
GO:0002660	positive regulation of peripheral tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.
GO:0002661	regulation of B cell tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of B cell tolerance induction.
GO:0002662	negative regulation of B cell tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.
GO:0002663	positive regulation of B cell tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.
GO:0002664	regulation of T cell tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of T cell tolerance induction.
GO:0002665	negative regulation of T cell tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.
GO:0002666	positive regulation of T cell tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.
GO:0002667	regulation of T cell anergy	biological_process	Any process that modulates the frequency, rate, or extent of T cell anergy.
GO:0002668	negative regulation of T cell anergy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.
GO:0002669	positive regulation of T cell anergy	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell anergy.
GO:0002670	regulation of B cell anergy	biological_process	Any process that modulates the frequency, rate, or extent of B cell anergy.
GO:0002671	negative regulation of B cell anergy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.
GO:0002672	positive regulation of B cell anergy	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell anergy.
GO:0002673	regulation of acute inflammatory response	biological_process	Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
GO:0002674	negative regulation of acute inflammatory response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
GO:0002675	positive regulation of acute inflammatory response	biological_process	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
GO:0002676	regulation of chronic inflammatory response	biological_process	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.
GO:0002677	negative regulation of chronic inflammatory response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.
GO:0002678	positive regulation of chronic inflammatory response	biological_process	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.
GO:0002679	respiratory burst involved in defense response	biological_process	A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0002680	pro-T cell lineage commitment	biological_process	The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.
GO:0002681	somatic recombination of T cell receptor gene segments	biological_process	The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.
GO:0002682	regulation of immune system process	biological_process	Any process that modulates the frequency, rate, or extent of an immune system process.
GO:0002683	negative regulation of immune system process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
GO:0002684	positive regulation of immune system process	biological_process	Any process that activates or increases the frequency, rate, or extent of an immune system process.
GO:0002685	regulation of leukocyte migration	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte migration.
GO:0002686	negative regulation of leukocyte migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.
GO:0002687	positive regulation of leukocyte migration	biological_process	Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
GO:0002688	regulation of leukocyte chemotaxis	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.
GO:0002689	negative regulation of leukocyte chemotaxis	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
GO:0002690	positive regulation of leukocyte chemotaxis	biological_process	Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
GO:0002691	regulation of cellular extravasation	biological_process	Any process that modulates the frequency, rate, or extent of cellular extravasation.
GO:0002692	negative regulation of cellular extravasation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.
GO:0002693	positive regulation of cellular extravasation	biological_process	Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
GO:0002694	regulation of leukocyte activation	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte activation.
GO:0002695	negative regulation of leukocyte activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
GO:0002696	positive regulation of leukocyte activation	biological_process	Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
GO:0002697	regulation of immune effector process	biological_process	Any process that modulates the frequency, rate, or extent of an immune effector process.
GO:0002698	negative regulation of immune effector process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
GO:0002699	positive regulation of immune effector process	biological_process	Any process that activates or increases the frequency, rate, or extent of an immune effector process.
GO:0002700	regulation of production of molecular mediator of immune response	biological_process	Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
GO:0002701	negative regulation of production of molecular mediator of immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
GO:0002702	positive regulation of production of molecular mediator of immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.
GO:0002703	regulation of leukocyte mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
GO:0002704	negative regulation of leukocyte mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
GO:0002705	positive regulation of leukocyte mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
GO:0002706	regulation of lymphocyte mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
GO:0002707	negative regulation of lymphocyte mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
GO:0002708	positive regulation of lymphocyte mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
GO:0002709	regulation of T cell mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of T cell mediated immunity.
GO:0002710	negative regulation of T cell mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.
GO:0002711	positive regulation of T cell mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.
GO:0002712	regulation of B cell mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
GO:0002713	negative regulation of B cell mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
GO:0002714	positive regulation of B cell mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
GO:0002715	regulation of natural killer cell mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.
GO:0002716	negative regulation of natural killer cell mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.
GO:0002717	positive regulation of natural killer cell mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
GO:0002718	regulation of cytokine production involved in immune response	biological_process	Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
GO:0002719	negative regulation of cytokine production involved in immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
GO:0002720	positive regulation of cytokine production involved in immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.
GO:0002721	regulation of B cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of B cell cytokine production.
GO:0002722	negative regulation of B cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.
GO:0002723	positive regulation of B cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.
GO:0002724	regulation of T cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of T cell cytokine production.
GO:0002725	negative regulation of T cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.
GO:0002726	positive regulation of T cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.
GO:0002727	regulation of natural killer cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.
GO:0002728	negative regulation of natural killer cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.
GO:0002729	positive regulation of natural killer cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
GO:0002730	regulation of dendritic cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.
GO:0002731	negative regulation of dendritic cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.
GO:0002732	positive regulation of dendritic cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.
GO:0002733	regulation of myeloid dendritic cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.
GO:0002734	negative regulation of myeloid dendritic cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.
GO:0002735	positive regulation of myeloid dendritic cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.
GO:0002736	regulation of plasmacytoid dendritic cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
GO:0002737	negative regulation of plasmacytoid dendritic cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
GO:0002738	positive regulation of plasmacytoid dendritic cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
GO:0002745	antigen processing and presentation initiated by receptor mediated uptake of antigen	biological_process	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.
GO:0002746	antigen processing and presentation following pinocytosis	biological_process	Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
GO:0002747	antigen processing and presentation following phagocytosis	biological_process	Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.
GO:0002748	antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen	biological_process	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).
GO:0002750	antigen processing and presentation following macropinocytosis	biological_process	Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.
GO:0002751	antigen processing and presentation following receptor mediated endocytosis	biological_process	Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.
GO:0002752	cell surface pattern recognition receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
GO:0002753	cytosolic pattern recognition receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand from another organism to a cytosolic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
GO:0002754	endosomal pattern recognition receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand to an intracellular vesicle pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	biological_process	A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0002756	MyD88-independent toll-like receptor signaling pathway	biological_process	A toll-like receptor signaling pathway not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate an immune response.
GO:0002757	immune response-activating signaling pathway	biological_process	The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.
GO:0002758	innate immune response-activating signaling pathway	biological_process	The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an innate immune response.
GO:0002759	regulation of antimicrobial humoral response	biological_process	Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.
GO:0002760	positive regulation of antimicrobial humoral response	biological_process	Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.
GO:0002761	regulation of myeloid leukocyte differentiation	biological_process	Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.
GO:0002762	negative regulation of myeloid leukocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
GO:0002763	positive regulation of myeloid leukocyte differentiation	biological_process	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
GO:0002764	immune response-regulating signaling pathway	biological_process	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.
GO:0002765	immune response-inhibiting signal transduction	biological_process	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.
GO:0002766	innate immune response-inhibiting signal transduction	biological_process	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.
GO:0002767	immune response-inhibiting cell surface receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of inhibiting an immune response.
GO:0002768	immune response-regulating cell surface receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
GO:0002769	natural killer cell inhibitory signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.
GO:0002770	T cell inhibitory signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.
GO:0002771	inhibitory killer cell immunoglobulin-like receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.
GO:0002772	inhibitory C-type lectin receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.
GO:0002773	B cell inhibitory signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.
GO:0002774	Fc receptor mediated inhibitory signaling pathway	biological_process	The series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
GO:0002775	antimicrobial peptide production	biological_process	The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
GO:0002776	antimicrobial peptide secretion	biological_process	The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
GO:0002777	antimicrobial peptide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
GO:0002778	antibacterial peptide production	biological_process	The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
GO:0002779	antibacterial peptide secretion	biological_process	The regulated release of an antibacterial peptide from a cell or a tissue.
GO:0002780	antibacterial peptide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an antibacterial peptide.
GO:0002781	antifungal peptide production	biological_process	The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
GO:0002782	antifungal peptide secretion	biological_process	The regulated release of an antifungal peptide from a cell or a tissue.
GO:0002783	antifungal peptide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an antifungal peptide.
GO:0002784	regulation of antimicrobial peptide production	biological_process	Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.
GO:0002785	negative regulation of antimicrobial peptide production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
GO:0002786	regulation of antibacterial peptide production	biological_process	Any process that modulates the frequency, rate, or extent of antibacterial peptide production.
GO:0002787	negative regulation of antibacterial peptide production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.
GO:0002788	regulation of antifungal peptide production	biological_process	Any process that modulates the frequency, rate, or extent of antifungal peptide production.
GO:0002789	negative regulation of antifungal peptide production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.
GO:0002790	peptide secretion	biological_process	The controlled release of a peptide from a cell or a tissue.
GO:0002791	regulation of peptide secretion	biological_process	Any process that modulates the frequency, rate, or extent of peptide secretion.
GO:0002792	negative regulation of peptide secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
GO:0002793	positive regulation of peptide secretion	biological_process	Any process that activates or increases the frequency, rate, or extent of peptide secretion.
GO:0002794	regulation of antimicrobial peptide secretion	biological_process	Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.
GO:0002795	negative regulation of antimicrobial peptide secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.
GO:0002796	positive regulation of antimicrobial peptide secretion	biological_process	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.
GO:0002797	regulation of antibacterial peptide secretion	biological_process	Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.
GO:0002798	negative regulation of antibacterial peptide secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.
GO:0002799	positive regulation of antibacterial peptide secretion	biological_process	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.
GO:0002800	regulation of antifungal peptide secretion	biological_process	Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.
GO:0002801	negative regulation of antifungal peptide secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.
GO:0002802	positive regulation of antifungal peptide secretion	biological_process	Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.
GO:0002803	positive regulation of antibacterial peptide production	biological_process	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.
GO:0002804	positive regulation of antifungal peptide production	biological_process	Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.
GO:0002805	regulation of antimicrobial peptide biosynthetic process	biological_process	Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.
GO:0002806	negative regulation of antimicrobial peptide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.
GO:0002807	positive regulation of antimicrobial peptide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.
GO:0002808	regulation of antibacterial peptide biosynthetic process	biological_process	Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.
GO:0002809	negative regulation of antibacterial peptide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.
GO:0002810	regulation of antifungal peptide biosynthetic process	biological_process	Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.
GO:0002811	negative regulation of antifungal peptide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.
GO:0002812	biosynthetic process of antibacterial peptides active against Gram-negative bacteria	biological_process	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
GO:0002813	regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	biological_process	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
GO:0002814	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
GO:0002815	biosynthetic process of antibacterial peptides active against Gram-positive bacteria	biological_process	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.
GO:0002816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	biological_process	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
GO:0002817	negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
GO:0002819	regulation of adaptive immune response	biological_process	Any process that modulates the frequency, rate, or extent of an adaptive immune response.
GO:0002820	negative regulation of adaptive immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
GO:0002821	positive regulation of adaptive immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological_process	Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	biological_process	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
GO:0002825	regulation of T-helper 1 type immune response	biological_process	Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.
GO:0002826	negative regulation of T-helper 1 type immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.
GO:0002827	positive regulation of T-helper 1 type immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
GO:0002828	regulation of type 2 immune response	biological_process	Any process that modulates the frequency, rate, or extent of a type 2 immune response.
GO:0002829	negative regulation of type 2 immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.
GO:0002830	positive regulation of type 2 immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.
GO:0002831	regulation of response to biotic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
GO:0002832	negative regulation of response to biotic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
GO:0002833	positive regulation of response to biotic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
GO:0002834	regulation of response to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of a response to tumor cell.
GO:0002835	negative regulation of response to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.
GO:0002836	positive regulation of response to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.
GO:0002837	regulation of immune response to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.
GO:0002838	negative regulation of immune response to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.
GO:0002839	positive regulation of immune response to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
GO:0002840	regulation of T cell mediated immune response to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
GO:0002841	negative regulation of T cell mediated immune response to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
GO:0002843	regulation of tolerance induction to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.
GO:0002844	negative regulation of tolerance induction to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.
GO:0002845	positive regulation of tolerance induction to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.
GO:0002846	regulation of T cell tolerance induction to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.
GO:0002847	negative regulation of T cell tolerance induction to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.
GO:0002848	positive regulation of T cell tolerance induction to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.
GO:0002849	regulation of peripheral T cell tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.
GO:0002850	negative regulation of peripheral T cell tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.
GO:0002851	positive regulation of peripheral T cell tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.
GO:0002852	regulation of T cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
GO:0002853	negative regulation of T cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
GO:0002854	positive regulation of T cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
GO:0002855	regulation of natural killer cell mediated immune response to tumor cell	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
GO:0002856	negative regulation of natural killer cell mediated immune response to tumor cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell	biological_process	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	biological_process	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
GO:0002861	regulation of inflammatory response to antigenic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
GO:0002867	regulation of B cell deletion	biological_process	Any process that modulates the frequency, rate, or extent of B cell deletion.
GO:0002868	negative regulation of B cell deletion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.
GO:0002869	positive regulation of B cell deletion	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell deletion.
GO:0002870	T cell anergy	biological_process	Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
GO:0002871	regulation of natural killer cell tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.
GO:0002872	negative regulation of natural killer cell tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.
GO:0002873	positive regulation of natural killer cell tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
GO:0002875	negative regulation of chronic inflammatory response to antigenic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
GO:0002878	negative regulation of acute inflammatory response to non-antigenic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
GO:0002880	regulation of chronic inflammatory response to non-antigenic stimulus	biological_process	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	biological_process	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
GO:0002883	regulation of hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of hypersensitivity.
GO:0002884	negative regulation of hypersensitivity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
GO:0002885	positive regulation of hypersensitivity	biological_process	Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
GO:0002886	regulation of myeloid leukocyte mediated immunity	biological_process	Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	biological_process	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
GO:0002889	regulation of immunoglobulin mediated immune response	biological_process	Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
GO:0002890	negative regulation of immunoglobulin mediated immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
GO:0002891	positive regulation of immunoglobulin mediated immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
GO:0002892	regulation of type II hypersensitivity	biological_process	Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
GO:0002893	negative regulation of type II hypersensitivity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.
GO:0002894	positive regulation of type II hypersensitivity	biological_process	Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
GO:0002895	regulation of central B cell tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.
GO:0002896	negative regulation of central B cell tolerance induction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.
GO:0002897	positive regulation of central B cell tolerance induction	biological_process	Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
GO:0002898	regulation of central B cell deletion	biological_process	Any process that modulates the frequency, rate, or extent of central B cell deletion.
GO:0002899	negative regulation of central B cell deletion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.
GO:0002900	positive regulation of central B cell deletion	biological_process	Any process that activates or increases the frequency, rate, or extent of central B cell deletion.
GO:0002901	mature B cell apoptotic process	biological_process	Any apoptotic process in a B cell that is mature, having left the bone marrow.
GO:0002902	regulation of B cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of B cell apoptotic process.
GO:0002903	negative regulation of B cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.
GO:0002904	positive regulation of B cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.
GO:0002905	regulation of mature B cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.
GO:0002906	negative regulation of mature B cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.
GO:0002907	positive regulation of mature B cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.
GO:0002908	regulation of peripheral B cell deletion	biological_process	Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.
GO:0002909	negative regulation of peripheral B cell deletion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.
GO:0002910	positive regulation of peripheral B cell deletion	biological_process	Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.
GO:0002911	regulation of lymphocyte anergy	biological_process	Any process that modulates the frequency, rate, or extent of lymphocyte anergy.
GO:0002912	negative regulation of lymphocyte anergy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.
GO:0002913	positive regulation of lymphocyte anergy	biological_process	Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.
GO:0002914	regulation of central B cell anergy	biological_process	Any process that modulates the frequency, rate, or extent of central B cell anergy.
GO:0002915	negative regulation of central B cell anergy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.
GO:0002916	positive regulation of central B cell anergy	biological_process	Any process that activates or increases the frequency, rate, or extent of central B cell anergy.
GO:0002917	regulation of peripheral B cell anergy	biological_process	Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.
GO:0002918	negative regulation of peripheral B cell anergy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.
GO:0002919	positive regulation of peripheral B cell anergy	biological_process	Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.
GO:0002920	regulation of humoral immune response	biological_process	Any process that modulates the frequency, rate, or extent of a humoral immune response.
GO:0002921	negative regulation of humoral immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
GO:0002922	positive regulation of humoral immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	biological_process	Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	biological_process	Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
GO:0002926	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation	biological_process	The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.
GO:0002927	archaeosine-tRNA biosynthetic process	biological_process	The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.
GO:0002929	MECO complex	cellular_component	A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.
GO:0002930	trabecular meshwork development	biological_process	The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.
GO:0002931	response to ischemia	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
GO:0002932	tendon sheath development	biological_process	The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.
GO:0002933	lipid hydroxylation	biological_process	The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
GO:0002934	desmosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
GO:0002935	tRNA (adenine-C2-)-methyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA.
GO:0002936	bradykinin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.
GO:0002937	tRNA 4-thiouridine biosynthesis	biological_process	The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.
GO:0002938	tRNA guanine ribose methylation	biological_process	The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.
GO:0002939	tRNA N1-guanine methylation	biological_process	The process whereby a guanine in tRNA is methylated at position N1 of the guanine.
GO:0002940	tRNA N2-guanine methylation	biological_process	The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.
GO:0002941	synoviocyte proliferation	biological_process	The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.
GO:0002942	tRNA m2,2-guanine biosynthesis	biological_process	The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.
GO:0002943	tRNA dihydrouridine synthesis	biological_process	The process whereby a uridine in a transfer RNA is converted to dihydrouridine.
GO:0002944	cyclin K-CDK12 complex	cellular_component	A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0002945	cyclin K-CDK13 complex	cellular_component	A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0002946	tRNA C5-cytosine methylation	biological_process	The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.
GO:0002947	tumor necrosis factor receptor superfamily complex	cellular_component	A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.
GO:0002948	archaeosine synthase activity	molecular_function	Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.
GO:0002949	tRNA threonylcarbamoyladenosine modification	biological_process	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
GO:0002950	ceramide phosphoethanolamine synthase activity	molecular_function	Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine.
GO:0002951	leukotriene-C(4) hydrolase	molecular_function	Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate.
GO:0002952	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	molecular_function	Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione.
GO:0002953	5'-deoxynucleotidase activity	molecular_function	Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate.
GO:0003002	regionalization	biological_process	The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
GO:0003003	follicular fluid formation in ovarian follicle antrum involved in fused antrum stage	biological_process	The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.
GO:0003004	follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage	biological_process	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.
GO:0003005	follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage	biological_process	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.
GO:0003006	developmental process involved in reproduction	biological_process	A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.
GO:0003007	heart morphogenesis	biological_process	The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
GO:0003008	system process	biological_process	A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
GO:0003009	skeletal muscle contraction	biological_process	A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.
GO:0003010	voluntary skeletal muscle contraction	biological_process	A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.
GO:0003011	involuntary skeletal muscle contraction	biological_process	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.
GO:0003012	muscle system process	biological_process	A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
GO:0003013	circulatory system process	biological_process	A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.
GO:0003014	renal system process	biological_process	A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
GO:0003015	heart process	biological_process	A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
GO:0003016	respiratory system process	biological_process	A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
GO:0003017	lymph circulation	biological_process	The flow of lymph through the body of an animal.
GO:0003018	vascular process in circulatory system	biological_process	A circulatory process that occurs at the level of the vasculature.
GO:0003019	central nervous system control of baroreceptor feedback	biological_process	The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.
GO:0003020	detection of reduced oxygen by chemoreceptor signaling	biological_process	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
GO:0003021	detection of increased carbon dioxide by chemoreceptor signaling	biological_process	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
GO:0003022	detection of pH by chemoreceptor signaling	biological_process	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.
GO:0003023	baroreceptor detection of increased arterial stretch	biological_process	The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.
GO:0003024	baroreceptor detection of decreased arterial stretch	biological_process	The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	biological_process	The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	biological_process	The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.
GO:0003027	regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling	biological_process	The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
GO:0003028	regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling	biological_process	The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	biological_process	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.
GO:0003030	detection of hydrogen ion	biological_process	The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.
GO:0003031	detection of carbon dioxide	biological_process	The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.
GO:0003032	detection of oxygen	biological_process	The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.
GO:0003033	detection of hypoxic conditions in blood by aortic body chemoreceptor signaling	biological_process	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.
GO:0003034	detection of increased carbon dioxide by aortic body chemoreceptor signaling	biological_process	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.
GO:0003035	detection of increased carbon dioxide by carotid body chemoreceptor signaling	biological_process	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.
GO:0003036	detection of pH by aortic body chemoreceptor signaling	biological_process	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.
GO:0003037	detection of pH by carotid body chemoreceptor signaling	biological_process	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.
GO:0003038	detection of reduced oxygen by aortic body chemoreceptor signaling	biological_process	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.
GO:0003039	detection of reduced oxygen by carotid body chemoreceptor signaling	biological_process	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.
GO:0003040	excitation of vasomotor center by aortic body chemoreceptor signaling	biological_process	The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
GO:0003041	excitation of vasomotor center by carotid body chemoreceptor signaling	biological_process	The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
GO:0003042	vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure	biological_process	A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
GO:0003043	vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure	biological_process	A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	biological_process	The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
GO:0003045	regulation of systemic arterial blood pressure by physical factors	biological_process	The regulation of blood pressure mediated by detection of forces within the circulatory system.
GO:0003046	regulation of systemic arterial blood pressure by stress relaxation	biological_process	The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.
GO:0003047	regulation of systemic arterial blood pressure by epinephrine	biological_process	The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.
GO:0003048	regulation of systemic arterial blood pressure by norepinephrine	biological_process	The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.
GO:0003049	regulation of systemic arterial blood pressure by capillary fluid shift	biological_process	The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	biological_process	The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.
GO:0003051	angiotensin-mediated drinking behavior	biological_process	The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.
GO:0003052	circadian regulation of systemic arterial blood pressure	biological_process	Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.
GO:0003053	circadian regulation of heart rate	biological_process	Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.
GO:0003054	circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus	biological_process	The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.
GO:0003055	circadian regulation of heart rate by the suprachiasmatic nucleus	biological_process	The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.
GO:0003056	regulation of vascular associated smooth muscle contraction	biological_process	Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.
GO:0003057	regulation of the force of heart contraction by chemical signal	biological_process	The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
GO:0003058	hormonal regulation of the force of heart contraction	biological_process	The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
GO:0003059	positive regulation of the force of heart contraction by epinephrine	biological_process	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.
GO:0003060	negative regulation of the force of heart contraction by acetylcholine	biological_process	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	biological_process	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.
GO:0003062	regulation of heart rate by chemical signal	biological_process	The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
GO:0003063	negative regulation of heart rate by acetylcholine	biological_process	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.
GO:0003064	regulation of heart rate by hormone	biological_process	The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
GO:0003065	positive regulation of heart rate by epinephrine	biological_process	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.
GO:0003066	positive regulation of heart rate by norepinephrine	biological_process	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.
GO:0003067	circadian regulation of systemic arterial blood pressure by hormone	biological_process	The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
GO:0003068	regulation of systemic arterial blood pressure by acetylcholine	biological_process	The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.
GO:0003069	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure	biological_process	The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.
GO:0003070	regulation of systemic arterial blood pressure by neurotransmitter	biological_process	The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	biological_process	Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
GO:0003072	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure	biological_process	The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature.
GO:0003073	regulation of systemic arterial blood pressure	biological_process	The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
GO:0003075	renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure	biological_process	The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	biological_process	The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.
GO:0003083	negative regulation of renal output by angiotensin	biological_process	The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.
GO:0003084	positive regulation of systemic arterial blood pressure	biological_process	The process that increases the force with which blood travels through the systemic arterial circulatory system.
GO:0003085	negative regulation of systemic arterial blood pressure	biological_process	The process that reduces the force with which blood travels through the systemic arterial circulatory system.
GO:0003086	regulation of systemic arterial blood pressure by local renal renin-angiotensin	biological_process	The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.
GO:0003087	positive regulation of the force of heart contraction by neuronal epinephrine	biological_process	The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.
GO:0003088	positive regulation of the force of heart contraction by circulating epinephrine	biological_process	The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.
GO:0003089	positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine	biological_process	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.
GO:0003090	positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine	biological_process	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.
GO:0003091	renal water homeostasis	biological_process	Renal process involved in the maintenance of an internal steady state of water in the body.
GO:0003092	renal water retention	biological_process	The process in which renal water excretion is decreased.
GO:0003093	regulation of glomerular filtration	biological_process	Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
GO:0003094	glomerular filtration	biological_process	The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.
GO:0003095	pressure natriuresis	biological_process	The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).
GO:0003096	renal sodium ion transport	biological_process	The directed movement of sodium ions (Na+) by the renal system.
GO:0003097	renal water transport	biological_process	The directed movement of water (H2O) by the renal system.
GO:0003098	tubuloglomerular feedback	biological_process	The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.
GO:0003099	positive regulation of the force of heart contraction by chemical signal	biological_process	Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
GO:0003100	regulation of systemic arterial blood pressure by endothelin	biological_process	The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.
GO:0003101	regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine	biological_process	The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.
GO:0003104	positive regulation of glomerular filtration	biological_process	Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
GO:0003105	negative regulation of glomerular filtration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
GO:0003106	negative regulation of glomerular filtration by angiotensin	biological_process	The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
GO:0003108	negative regulation of the force of heart contraction by chemical signal	biological_process	Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
GO:0003109	positive regulation of the force of heart contraction by circulating norepinephrine	biological_process	The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.
GO:0003110	positive regulation of the force of heart contraction by neuronal norepinephrine	biological_process	The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.
GO:0003111	positive regulation of heart rate by circulating epinephrine	biological_process	The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.
GO:0003112	positive regulation of heart rate by neuronal epinephrine	biological_process	The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction.
GO:0003113	positive regulation of heart rate by neuronal norepinephrine	biological_process	The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.
GO:0003114	positive regulation of heart rate by circulating norepinephrine	biological_process	The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.
GO:0003115	regulation of vasoconstriction by epinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.
GO:0003116	regulation of vasoconstriction by norepinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.
GO:0003117	regulation of vasoconstriction by circulating norepinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
GO:0003118	regulation of vasoconstriction by neuronal norepinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings.
GO:0003119	regulation of vasoconstriction by neuronal epinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.
GO:0003120	regulation of vasoconstriction by circulating epinephrine	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.
GO:0003121	epinephrine-mediated vasodilation	biological_process	A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.
GO:0003122	norepinephrine-mediated vasodilation	biological_process	A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings.
GO:0003127	detection of nodal flow	biological_process	The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.
GO:0003128	heart field specification	biological_process	The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.
GO:0003129	heart induction	biological_process	The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
GO:0003131	mesodermal-endodermal cell signaling	biological_process	Any process that mediates the transfer of information from mesodermal cells to endodermal cells.
GO:0003132	mesodermal-endodermal cell signaling involved in heart induction	biological_process	Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction.
GO:0003133	endodermal-mesodermal cell signaling	biological_process	Any process that mediates the transfer of information from endodermal cells to mesodermal cells.
GO:0003134	endodermal-mesodermal cell signaling involved in heart induction	biological_process	Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.
GO:0003135	fibroblast growth factor receptor signaling pathway involved in heart induction	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction.
GO:0003136	negative regulation of heart induction by canonical Wnt signaling pathway	biological_process	Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction.
GO:0003137	Notch signaling pathway involved in heart induction	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
GO:0003138	primary heart field specification	biological_process	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.
GO:0003139	secondary heart field specification	biological_process	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
GO:0003140	determination of left/right asymmetry in lateral mesoderm	biological_process	The establishment of the lateral mesoderm with respect to the left and right halves.
GO:0003142	cardiogenic plate morphogenesis	biological_process	The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.
GO:0003143	embryonic heart tube morphogenesis	biological_process	The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
GO:0003144	embryonic heart tube formation	biological_process	The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
GO:0003145	embryonic heart tube formation via epithelial folding	biological_process	The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.
GO:0003146	heart jogging	biological_process	The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
GO:0003147	neural crest cell migration involved in heart formation	biological_process	The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.
GO:0003148	outflow tract septum morphogenesis	biological_process	The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
GO:0003149	membranous septum morphogenesis	biological_process	The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.
GO:0003150	muscular septum morphogenesis	biological_process	The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.
GO:0003151	outflow tract morphogenesis	biological_process	The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
GO:0003152	morphogenesis of an epithelial fold involved in embryonic heart tube formation	biological_process	The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.
GO:0003153	closure of embryonic heart tube	biological_process	Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.
GO:0003156	regulation of animal organ formation	biological_process	Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.
GO:0003157	endocardium development	biological_process	The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0003158	endothelium development	biological_process	The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
GO:0003159	morphogenesis of an endothelium	biological_process	The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
GO:0003160	endocardium morphogenesis	biological_process	The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0003161	cardiac conduction system development	biological_process	The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.
GO:0003162	atrioventricular node development	biological_process	The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.
GO:0003163	sinoatrial node development	biological_process	The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.
GO:0003164	His-Purkinje system development	biological_process	The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.
GO:0003165	Purkinje myocyte development	biological_process	The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.
GO:0003166	bundle of His development	biological_process	The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.
GO:0003167	atrioventricular bundle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.
GO:0003168	Purkinje myocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.
GO:0003169	coronary vein morphogenesis	biological_process	The process in which the anatomical structures of veins of the heart are generated and organized.
GO:0003170	heart valve development	biological_process	The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.
GO:0003171	atrioventricular valve development	biological_process	The progression of the atrioventricular valve over time, from its formation to the mature structure.
GO:0003172	sinoatrial valve development	biological_process	The progression of the sinoatrial valve over time, from its formation to the mature structure.
GO:0003173	ventriculo bulbo valve development	biological_process	The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.
GO:0003174	mitral valve development	biological_process	The progression of the mitral valve over time, from its formation to the mature structure.
GO:0003175	tricuspid valve development	biological_process	The progression of the tricuspid valve over time, from its formation to the mature structure.
GO:0003176	aortic valve development	biological_process	The progression of the aortic valve over time, from its formation to the mature structure.
GO:0003177	pulmonary valve development	biological_process	The progression of the pulmonary valve over time, from its formation to the mature structure.
GO:0003178	coronary sinus valve development	biological_process	The progression of the valve of the coronary sinus over time, from its formation to the mature structure.
GO:0003179	heart valve morphogenesis	biological_process	The process in which the structure of a heart valve is generated and organized.
GO:0003180	aortic valve morphogenesis	biological_process	The process in which the structure of the aortic valve is generated and organized.
GO:0003181	atrioventricular valve morphogenesis	biological_process	The process in which the structure of the atrioventricular valve is generated and organized.
GO:0003182	coronary sinus valve morphogenesis	biological_process	The process in which the structure of the coronary sinus valve is generated and organized.
GO:0003183	mitral valve morphogenesis	biological_process	The process in which the structure of the mitral valve is generated and organized.
GO:0003184	pulmonary valve morphogenesis	biological_process	The process in which the structure of the pulmonary valve is generated and organized.
GO:0003185	sinoatrial valve morphogenesis	biological_process	The process in which the structure of the sinoatrial valve is generated and organized.
GO:0003186	tricuspid valve morphogenesis	biological_process	The process in which the structure of the tricuspid valve is generated and organized.
GO:0003187	ventriculo bulbo valve morphogenesis	biological_process	The process in which the structure of the ventriculo bulbo valve is generated and organized.
GO:0003188	heart valve formation	biological_process	The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003189	aortic valve formation	biological_process	The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003190	atrioventricular valve formation	biological_process	The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003191	coronary sinus valve formation	biological_process	The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003192	mitral valve formation	biological_process	The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003193	pulmonary valve formation	biological_process	The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003194	sinoatrial valve formation	biological_process	The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003195	tricuspid valve formation	biological_process	The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003196	ventriculo bulbo valve formation	biological_process	The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
GO:0003197	endocardial cushion development	biological_process	The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	biological_process	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	biological_process	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.
GO:0003200	endocardial cushion to mesenchymal transition involved in heart chamber septation	biological_process	A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.
GO:0003201	epithelial to mesenchymal transition involved in coronary vasculature morphogenesis	biological_process	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature.
GO:0003202	endocardial cushion to mesenchymal transition involved in cardiac skeleton development	biological_process	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton.
GO:0003203	endocardial cushion morphogenesis	biological_process	The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
GO:0003204	cardiac skeleton development	biological_process	The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.
GO:0003205	cardiac chamber development	biological_process	The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.
GO:0003206	cardiac chamber morphogenesis	biological_process	The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.
GO:0003207	cardiac chamber formation	biological_process	The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.
GO:0003208	cardiac ventricle morphogenesis	biological_process	The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
GO:0003209	cardiac atrium morphogenesis	biological_process	The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
GO:0003210	cardiac atrium formation	biological_process	The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
GO:0003211	cardiac ventricle formation	biological_process	The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
GO:0003212	cardiac left atrium morphogenesis	biological_process	The process in which the left cardiac atrium is generated and organized.
GO:0003213	cardiac right atrium morphogenesis	biological_process	The process in which the right cardiac atrium is generated and organized.
GO:0003214	cardiac left ventricle morphogenesis	biological_process	The process in which the left cardiac ventricle is generated and organized.
GO:0003215	cardiac right ventricle morphogenesis	biological_process	The process in which the right cardiac ventricle is generated and organized.
GO:0003216	cardiac left atrium formation	biological_process	The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.
GO:0003217	cardiac right atrium formation	biological_process	The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.
GO:0003218	cardiac left ventricle formation	biological_process	The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.
GO:0003219	cardiac right ventricle formation	biological_process	The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.
GO:0003220	left ventricular cardiac muscle tissue morphogenesis	biological_process	The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	biological_process	The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.
GO:0003222	ventricular trabecula myocardium morphogenesis	biological_process	The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.
GO:0003223	ventricular compact myocardium morphogenesis	biological_process	The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.
GO:0003224	left ventricular compact myocardium morphogenesis	biological_process	The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.
GO:0003225	left ventricular trabecular myocardium morphogenesis	biological_process	The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.
GO:0003226	right ventricular compact myocardium morphogenesis	biological_process	The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.
GO:0003227	right ventricular trabecular myocardium morphogenesis	biological_process	The process in which the anatomical structures of the right ventricular myocardium are generated and organized.
GO:0003228	atrial cardiac muscle tissue development	biological_process	The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.
GO:0003229	ventricular cardiac muscle tissue development	biological_process	The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.
GO:0003230	cardiac atrium development	biological_process	The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
GO:0003231	cardiac ventricle development	biological_process	The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
GO:0003232	bulbus arteriosus development	biological_process	The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.
GO:0003233	bulbus arteriosus morphogenesis	biological_process	The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.
GO:0003234	bulbus arteriosus formation	biological_process	The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.
GO:0003235	sinus venosus development	biological_process	The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
GO:0003236	sinus venosus morphogenesis	biological_process	The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
GO:0003237	sinus venosus formation	biological_process	The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
GO:0003238	conus arteriosus development	biological_process	The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
GO:0003239	conus arteriosus morphogenesis	biological_process	The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
GO:0003240	conus arteriosus formation	biological_process	The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
GO:0003241	growth involved in heart morphogenesis	biological_process	Developmental growth that contributes to the shaping of the heart.
GO:0003242	cardiac chamber ballooning	biological_process	The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.
GO:0003243	circumferential growth involved in left ventricle morphogenesis	biological_process	The morphogenetic growth in which the left ventricle grows expanding its external boundary.
GO:0003244	radial growth involved in right ventricle morphogenesis	biological_process	The morphogenic growth in which the right ventricle grows along a radial axis.
GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis	biological_process	The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.
GO:0003246	embryonic cardiac muscle cell growth involved in heart morphogenesis	biological_process	The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart.
GO:0003247	post-embryonic cardiac muscle cell growth involved in heart morphogenesis	biological_process	The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart.
GO:0003248	heart capillary growth	biological_process	The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.
GO:0003249	cell proliferation involved in heart valve morphogenesis	biological_process	The multiplication or reproduction of cells that contributes to the shaping of a heart valve.
GO:0003250	regulation of cell proliferation involved in heart valve morphogenesis	biological_process	Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis	biological_process	Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
GO:0003252	negative regulation of cell proliferation involved in heart valve morphogenesis	biological_process	Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	biological_process	The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.
GO:0003254	regulation of membrane depolarization	biological_process	Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.
GO:0003255	endocardial precursor cell differentiation	biological_process	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate.
GO:0003259	cardioblast anterior-lateral migration	biological_process	The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003260	cardioblast migration	biological_process	The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003261	cardiac muscle progenitor cell migration to the midline involved in heart field formation	biological_process	The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart.
GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation	biological_process	The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.
GO:0003263	cardioblast proliferation	biological_process	The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003264	regulation of cardioblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003265	regulation of primary heart field cardioblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.
GO:0003266	regulation of secondary heart field cardioblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
GO:0003267	canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation	biological_process	A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003268	fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003271	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0003272	endocardial cushion formation	biological_process	The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
GO:0003273	cell migration involved in endocardial cushion formation	biological_process	The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
GO:0003274	endocardial cushion fusion	biological_process	The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.
GO:0003275	apoptotic process involved in outflow tract morphogenesis	biological_process	Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.
GO:0003276	apoptotic process involved in heart valve morphogenesis	biological_process	Any apoptotic process that contributes to the shaping of a heart valve.
GO:0003277	apoptotic process involved in endocardial cushion morphogenesis	biological_process	Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
GO:0003278	apoptotic process involved in heart morphogenesis	biological_process	Any apoptotic process that contributes to the shaping of the heart.
GO:0003279	cardiac septum development	biological_process	The progression of a cardiac septum over time, from its initial formation to the mature structure.
GO:0003281	ventricular septum development	biological_process	The progression of the ventricular septum over time from its formation to the mature structure.
GO:0003282	ventricular septum intermedium development	biological_process	The progression of the ventricular septum intermedium over time, from its formation to the mature structure.
GO:0003283	atrial septum development	biological_process	The progression of the atrial septum over time, from its initial formation to the mature structure.
GO:0003284	septum primum development	biological_process	The progression of the septum primum over time, from its formation to the mature structure.
GO:0003285	septum secundum development	biological_process	The progression of the septum secundum over time, from its initial formation to the mature structure.
GO:0003286	atrial septum intermedium development	biological_process	The progression of the atrial septum intermedium over time, from its formation to the mature structure.
GO:0003288	ventricular septum intermedium morphogenesis	biological_process	The developmental process in which a ventricular septum intermedium is generated and organized.
GO:0003289	atrial septum primum morphogenesis	biological_process	The process in which anatomical structure of an atrial septum primum is generated and organized.
GO:0003290	atrial septum secundum morphogenesis	biological_process	The process in which anatomical structure of an atrial septum secundum is generated and organized.
GO:0003291	atrial septum intermedium morphogenesis	biological_process	The process in which anatomical structure of an atrial septum intermedium is generated and organized.
GO:0003292	cardiac septum cell differentiation	biological_process	The process in which an endocardial cushion cell becomes a cell of a cardiac septum.
GO:0003293	heart valve cell differentiation	biological_process	The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.
GO:0003294	atrial ventricular junction remodeling	biological_process	The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.
GO:0003295	cell proliferation involved in atrial ventricular junction remodeling	biological_process	The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.
GO:0003296	apoptotic process involved in atrial ventricular junction remodeling	biological_process	Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.
GO:0003297	heart wedging	biological_process	The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart.
GO:0003298	physiological muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.
GO:0003299	muscle hypertrophy in response to stress	biological_process	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.
GO:0003300	cardiac muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.
GO:0003301	physiological cardiac muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.
GO:0003304	myocardial epithelial involution involved in heart jogging	biological_process	The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging.
GO:0003305	cell migration involved in heart jogging	biological_process	The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.
GO:0003306	Wnt signaling pathway involved in heart development	biological_process	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
GO:0003307	regulation of Wnt signaling pathway involved in heart development	biological_process	Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
GO:0003308	negative regulation of Wnt signaling pathway involved in heart development	biological_process	Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
GO:0003309	type B pancreatic cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
GO:0003310	pancreatic A cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
GO:0003311	pancreatic D cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.
GO:0003312	pancreatic PP cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
GO:0003313	heart rudiment development	biological_process	The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.
GO:0003314	heart rudiment morphogenesis	biological_process	The process in which the anatomical structures of the heart rudiment are generated and organized.
GO:0003315	heart rudiment formation	biological_process	The developmental process pertaining to the initial formation of the heart rudiment.
GO:0003316	establishment of myocardial progenitor cell apical/basal polarity	biological_process	The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment.
GO:0003317	cardioblast cell midline fusion	biological_process	The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment.
GO:0003318	cell migration to the midline involved in heart development	biological_process	The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.
GO:0003319	cardioblast migration to the midline involved in heart rudiment formation	biological_process	The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.
GO:0003320	heart rudiment involution	biological_process	The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube.
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	biological_process	Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.
GO:0003322	pancreatic A cell development	biological_process	The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
GO:0003323	type B pancreatic cell development	biological_process	The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
GO:0003324	pancreatic D cell development	biological_process	The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.
GO:0003325	pancreatic PP cell development	biological_process	The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
GO:0003326	pancreatic A cell fate commitment	biological_process	The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
GO:0003327	type B pancreatic cell fate commitment	biological_process	The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
GO:0003328	pancreatic D cell fate commitment	biological_process	The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin.
GO:0003329	pancreatic PP cell fate commitment	biological_process	The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
GO:0003330	regulation of extracellular matrix constituent secretion	biological_process	Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
GO:0003331	positive regulation of extracellular matrix constituent secretion	biological_process	Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
GO:0003332	negative regulation of extracellular matrix constituent secretion	biological_process	Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
GO:0003333	amino acid transmembrane transport	biological_process	The process in which an amino acid is transported across a membrane.
GO:0003334	keratinocyte development	biological_process	The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.
GO:0003335	corneocyte development	biological_process	The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.
GO:0003336	corneocyte desquamation	biological_process	The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
GO:0003338	metanephros morphogenesis	biological_process	The process in which the anatomical structures of the metanephros are generated and organized.
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	biological_process	Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	biological_process	Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
GO:0003341	cilium movement	biological_process	The directed, self-propelled movement of a cilium.
GO:0003342	proepicardium development	biological_process	The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.
GO:0003343	septum transversum development	biological_process	The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.
GO:0003344	pericardium morphogenesis	biological_process	The process in which the anatomical structure of the pericardium is generated and organized.
GO:0003345	proepicardium cell migration involved in pericardium morphogenesis	biological_process	The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.
GO:0003346	epicardium-derived cell migration to the myocardium	biological_process	The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.
GO:0003347	epicardial cell to mesenchymal cell transition	biological_process	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.
GO:0003348	cardiac endothelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	biological_process	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
GO:0003350	pulmonary myocardium development	biological_process	The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.
GO:0003351	epithelial cilium movement involved in extracellular fluid movement	biological_process	The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.
GO:0003352	regulation of cilium movement	biological_process	Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GO:0003353	positive regulation of cilium movement	biological_process	Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GO:0003354	negative regulation of cilium movement	biological_process	Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
GO:0003355	cilium movement involved in otolith formation	biological_process	The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.
GO:0003356	regulation of cilium beat frequency	biological_process	Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.
GO:0003357	noradrenergic neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.
GO:0003358	noradrenergic neuron development	biological_process	The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0003359	noradrenergic neuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.
GO:0003360	brainstem development	biological_process	The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.
GO:0003361	noradrenergic neuron differentiation involved in brainstem development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.
GO:0003362	noradrenergic neuron fate commitment involved in brainstem development	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.
GO:0003363	lamellipodium assembly involved in ameboidal cell migration	biological_process	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.
GO:0003364	lamellipodium assembly involved in mesendodermal cell migration	biological_process	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell.
GO:0003365	establishment of cell polarity involved in ameboidal cell migration	biological_process	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.
GO:0003366	cell-matrix adhesion involved in ameboidal cell migration	biological_process	The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.
GO:0003367	cell-cell adhesion involved in ameboidal cell migration	biological_process	The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.
GO:0003368	cell-matrix adhesion involved in mesendodermal cell migration	biological_process	The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell.
GO:0003369	establishment of cell polarity involved in mesendodermal cell migration	biological_process	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.
GO:0003370	cell-cell adhesion involved in mesendodermal cell migration	biological_process	The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.
GO:0003371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.
GO:0003372	establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell.
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by sphingosine-1-phosphate binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0003379	establishment of cell polarity involved in gastrulation cell migration	biological_process	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.
GO:0003380	establishment or maintenance of cytoskeleton polarity involved in gastrulation	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.
GO:0003381	epithelial cell morphogenesis involved in gastrulation	biological_process	The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.
GO:0003382	epithelial cell morphogenesis	biological_process	The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.
GO:0003383	apical constriction	biological_process	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.
GO:0003384	apical constriction involved in gastrulation	biological_process	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
GO:0003385	cell-cell signaling involved in amphid sensory organ development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.
GO:0003386	amphid sensory organ development	biological_process	The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.
GO:0003387	neuron differentiation involved in amphid sensory organ development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.
GO:0003388	neuron development involved in amphid sensory organ development	biological_process	The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.
GO:0003389	retrograde extension	biological_process	The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
GO:0003390	dendrite development by retrograde extension	biological_process	The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.
GO:0003391	amphid sensory organ dendrite retrograde extension	biological_process	The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
GO:0003392	cell adhesion involved in retrograde extension	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.
GO:0003393	neuron migration involved in retrograde extension	biological_process	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.
GO:0003394	cell adhesion involved in dendrite retrograde extension	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite.
GO:0003395	neuron migration involved in dendrite retrograde extension	biological_process	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite.
GO:0003396	cell adhesion involved in amphid sensory organ dendrite retrograde extension	biological_process	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ.
GO:0003397	neuron migration involved in amphid sensory organ dendrite retrograde extension	biological_process	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ.
GO:0003398	glial cell differentiation involved in amphid sensory organ development	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.
GO:0003399	cytoneme morphogenesis	biological_process	The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.
GO:0003400	regulation of COPII vesicle coating	biological_process	Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
GO:0003401	axis elongation	biological_process	The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.
GO:0003402	planar cell polarity pathway involved in axis elongation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation.
GO:0003403	optic vesicle formation	biological_process	The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
GO:0003404	optic vesicle morphogenesis	biological_process	The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
GO:0003405	optic vesicle elongation	biological_process	The developmental growth that results in the lengthening of the optic vesicle in the posterior direction.
GO:0003406	retinal pigment epithelium development	biological_process	The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.
GO:0003407	neural retina development	biological_process	The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
GO:0003408	optic cup formation involved in camera-type eye development	biological_process	The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.
GO:0003409	optic cup structural organization	biological_process	The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.
GO:0003410	anterior rotation of the optic cup	biological_process	A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis.
GO:0003411	cell motility involved in camera-type eye morphogenesis	biological_process	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.
GO:0003412	establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis	biological_process	The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	biological_process	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
GO:0003414	chondrocyte morphogenesis involved in endochondral bone morphogenesis	biological_process	The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.
GO:0003415	chondrocyte hypertrophy	biological_process	The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.
GO:0003416	endochondral bone growth	biological_process	The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.
GO:0003417	growth plate cartilage development	biological_process	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.
GO:0003418	growth plate cartilage chondrocyte differentiation	biological_process	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
GO:0003419	growth plate cartilage chondrocyte proliferation	biological_process	The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	biological_process	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
GO:0003421	growth plate cartilage axis specification	biological_process	The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.
GO:0003422	growth plate cartilage morphogenesis	biological_process	The process in which the anatomical structures of growth plate cartilage are generated and organized.
GO:0003423	growth plate cartilage chondrocyte division	biological_process	The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.
GO:0003424	establishment of cell polarity involved in growth plate cartilage chondrocyte division	biological_process	The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.
GO:0003425	establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division	biological_process	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate.
GO:0003426	cytoskeleton polarization involved in growth plate cartilage chondrocyte division	biological_process	A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.
GO:0003427	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.
GO:0003428	chondrocyte intercalation involved in growth plate cartilage morphogenesis	biological_process	The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.
GO:0003429	growth plate cartilage chondrocyte morphogenesis	biological_process	The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.
GO:0003430	growth plate cartilage chondrocyte growth	biological_process	The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.
GO:0003431	growth plate cartilage chondrocyte development	biological_process	The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.
GO:0003432	cell growth involved in growth plate cartilage chondrocyte morphogenesis	biological_process	The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.
GO:0003433	chondrocyte development involved in endochondral bone morphogenesis	biological_process	The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.
GO:0003435	smoothened signaling pathway involved in growth plate cartilage chondrocyte development	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time.
GO:0003436	regulation of cell adhesion involved in growth plate cartilage morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.
GO:0003437	regulation of cell communication involved in growth plate cartilage morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.
GO:0003674	molecular_function	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003676	nucleic acid binding	molecular_function	Binding to a nucleic acid.
GO:0003677	DNA binding	molecular_function	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003678	DNA helicase activity	molecular_function	Unwinding of a DNA helix, driven by ATP hydrolysis.
GO:0003680	minor groove of adenine-thymine-rich DNA binding	molecular_function	Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins.
GO:0003681	bent DNA binding	molecular_function	Binding to DNA in a bent conformation.
GO:0003682	chromatin binding	molecular_function	Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
GO:0003684	damaged DNA binding	molecular_function	Binding to damaged DNA.
GO:0003688	DNA replication origin binding	molecular_function	Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
GO:0003689	DNA clamp loader activity	molecular_function	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.
GO:0003690	double-stranded DNA binding	molecular_function	Binding to double-stranded DNA.
GO:0003691	double-stranded telomeric DNA binding	molecular_function	Binding to double-stranded telomere-associated DNA.
GO:0003692	left-handed Z-DNA binding	molecular_function	Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.
GO:0003693	P-element binding	molecular_function	Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.
GO:0003696	satellite DNA binding	molecular_function	Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.
GO:0003697	single-stranded DNA binding	molecular_function	Binding to single-stranded DNA.
GO:0003700	DNA-binding transcription factor activity	molecular_function	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
GO:0003707	nuclear steroid receptor activity	molecular_function	Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
GO:0003711	transcription elongation factor activity	molecular_function	A molecular function that stimulates the elongation properties of the RNA polymerase during the elongation phase of transcription. A subclass of transcription elongation factors enable the transition from transcription initiation to elongation, while another class rescue stalled RNA polymerases.
GO:0003712	transcription coregulator activity	molecular_function	A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
GO:0003713	transcription coactivator activity	molecular_function	A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.
GO:0003714	transcription corepressor activity	molecular_function	A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
GO:0003720	telomerase activity	molecular_function	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
GO:0003721	telomerase RNA reverse transcriptase activity	molecular_function	Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.
GO:0003723	RNA binding	molecular_function	Binding to an RNA molecule or a portion thereof.
GO:0003724	RNA helicase activity	molecular_function	Unwinding of an RNA helix, driven by ATP hydrolysis.
GO:0003725	double-stranded RNA binding	molecular_function	Binding to double-stranded RNA.
GO:0003726	double-stranded RNA adenosine deaminase activity	molecular_function	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
GO:0003727	single-stranded RNA binding	molecular_function	Binding to single-stranded RNA.
GO:0003729	mRNA binding	molecular_function	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
GO:0003730	mRNA 3'-UTR binding	molecular_function	Binding to a 3' untranslated region of an mRNA molecule.
GO:0003735	structural constituent of ribosome	molecular_function	The action of a molecule that contributes to the structural integrity of the ribosome.
GO:0003743	translation initiation factor activity	molecular_function	Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
GO:0003746	translation elongation factor activity	molecular_function	Functions in chain elongation during polypeptide synthesis at the ribosome.
GO:0003747	translation release factor activity	molecular_function	Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	molecular_function	Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
GO:0003756	protein disulfide isomerase activity	molecular_function	Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
GO:0003774	cytoskeletal motor activity	molecular_function	Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).
GO:0003777	microtubule motor activity	molecular_function	A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.
GO:0003779	actin binding	molecular_function	Binding to monomeric or multimeric forms of actin, including actin filaments.
GO:0003785	actin monomer binding	molecular_function	Binding to monomeric actin, also known as G-actin.
GO:0003786	actin lateral binding	molecular_function	Binding to an actin filament along its length.
GO:0003789	actin filament severing activity	molecular_function	Binding to an actin subunit and promoting its dissociation from an actin filament by a local change in actin subunit conformation and orientation, and severing of filaments.
GO:0003796	lysozyme activity	molecular_function	Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.
GO:0003810	protein-glutamine gamma-glutamyltransferase activity	molecular_function	Catalysis of the reaction: L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4+. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.
GO:0003823	antigen binding	molecular_function	Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
GO:0003824	catalytic activity	molecular_function	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003825	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	molecular_function	Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.
GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H+ + UDP.
GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.
GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.
GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
GO:0003832	beta-alanyl-dopamine hydrolase activity	molecular_function	Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine.
GO:0003833	beta-alanyl amine synthase activity	molecular_function	Catalysis of the synthesis of beta-alanyl amine conjugate from a precursor biogenic amine, such as dopamine or histamine.
GO:0003834	beta-carotene 15,15'-dioxygenase activity	molecular_function	Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.
GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactoside = N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H+.
GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.
GO:0003837	beta-ureidopropionase activity	molecular_function	Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3.
GO:0003838	sterol 24-C-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.
GO:0003839	gamma-glutamylcyclotransferase activity	molecular_function	Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	molecular_function	H2O + L-glutamate 5-semialdehyde + NAD+ = 2 H+ + L-glutamate + NADH.
GO:0003843	1,3-beta-D-glucan synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).
GO:0003844	1,4-alpha-glucan branching enzyme activity	molecular_function	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	molecular_function	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.
GO:0003846	2-acylglycerol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.
GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity	molecular_function	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.
GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	molecular_function	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H+.
GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity	molecular_function	Catalysis of the reaction: D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.
GO:0003850	2-deoxyglucose-6-phosphatase activity	molecular_function	Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.
GO:0003851	2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.
GO:0003852	2-isopropylmalate synthase activity	molecular_function	Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H+.
GO:0003853	2-methylacyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein].
GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	molecular_function	Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+.
GO:0003855	3-dehydroquinate dehydratase activity	molecular_function	Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H2O.
GO:0003856	3-dehydroquinate synthase activity	molecular_function	Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.
GO:0003858	3-hydroxybutyrate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.
GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
GO:0003861	3-isopropylmalate dehydratase activity	molecular_function	Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
GO:0003862	3-isopropylmalate dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.
GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	molecular_function	Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.
GO:0003864	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.
GO:0003866	3-phosphoshikimate 1-carboxyvinyltransferase activity	molecular_function	Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
GO:0003867	4-aminobutyrate transaminase activity	molecular_function	Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.
GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity	molecular_function	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.
GO:0003870	5-aminolevulinate synthase activity	molecular_function	Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA.
GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.
GO:0003872	6-phosphofructokinase activity	molecular_function	Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
GO:0003873	6-phosphofructo-2-kinase activity	molecular_function	Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H+.
GO:0003874	6-pyruvoyltetrahydropterin synthase activity	molecular_function	Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H+ + triphosphate.
GO:0003875	ADP-ribosylarginine hydrolase activity	molecular_function	Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose.
GO:0003876	AMP deaminase activity	molecular_function	Catalysis of the reaction: AMP + H2O = IMP + NH3.
GO:0003877	ATP adenylyltransferase activity	molecular_function	Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.
GO:0003878	ATP citrate synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + ADP + H+ + oxaloacetate + phosphate = ATP + citrate + CoA.
GO:0003879	ATP phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0003880	protein C-terminal carboxyl O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H+.
GO:0003882	CDP-diacylglycerol-serine O-phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
GO:0003883	CTP synthase activity	molecular_function	Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
GO:0003884	D-amino-acid oxidase activity	molecular_function	Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.
GO:0003885	D-arabinono-1,4-lactone oxidase activity	molecular_function	Catalysis of the reaction: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H+.
GO:0003886	DNA (cytosine-5-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
GO:0003887	DNA-directed DNA polymerase activity	molecular_function	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
GO:0003896	DNA primase activity	molecular_function	Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO:0003904	deoxyribodipyrimidine photo-lyase activity	molecular_function	Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.
GO:0003905	alkylbase DNA N-glycosylase activity	molecular_function	Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	molecular_function	Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).
GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
GO:0003909	DNA ligase activity	molecular_function	Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
GO:0003910	DNA ligase (ATP) activity	molecular_function	Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).
GO:0003911	DNA ligase (NAD+) activity	molecular_function	Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).
GO:0003912	DNA nucleotidylexotransferase activity	molecular_function	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
GO:0003913	DNA photolyase activity	molecular_function	Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.
GO:0003914	DNA (6-4) photolyase activity	molecular_function	Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.
GO:0003916	DNA topoisomerase activity	molecular_function	Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	molecular_function	Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	molecular_function	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
GO:0003919	FMN adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + FMN = diphosphate + FAD.
GO:0003920	GMP reductase activity	molecular_function	Catalysis of the reaction: IMP + NADP+ + NH4 = GMP + 2 H+ + NADPH.
GO:0003921	GMP synthase activity	molecular_function	Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H+.
GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+.
GO:0003923	GPI-anchor transamidase activity	molecular_function	Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.
GO:0003924	GTPase activity	molecular_function	Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
GO:0003925	G protein activity	molecular_function	A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).
GO:0003933	GTP cyclohydrolase activity	molecular_function	Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
GO:0003934	GTP cyclohydrolase I activity	molecular_function	Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
GO:0003935	GTP cyclohydrolase II activity	molecular_function	Catalysis of the reaction: GTP + 3 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H+.
GO:0003937	IMP cyclohydrolase activity	molecular_function	Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.
GO:0003938	IMP dehydrogenase activity	molecular_function	Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
GO:0003939	L-iditol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.
GO:0003940	L-iduronidase activity	molecular_function	Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
GO:0003941	L-serine ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-serine = pyruvate + NH3.
GO:0003942	N-acetyl-gamma-glutamyl-phosphate reductase activity	molecular_function	Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.
GO:0003943	N-acetylgalactosamine-4-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.
GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	molecular_function	Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.
GO:0003945	N-acetyllactosamine synthase activity	molecular_function	Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.
GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.
GO:0003948	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	molecular_function	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H+.
GO:0003949	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	molecular_function	Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
GO:0003950	NAD+ ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
GO:0003951	NAD+ kinase activity	molecular_function	Catalysis of the reaction: ATP + NAD+ = ADP + 2 H+ + NADP+.
GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
GO:0003953	NAD+ nucleosidase activity	molecular_function	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose.
GO:0003954	NADH dehydrogenase activity	molecular_function	Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
GO:0003955	NAD(P)H dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
GO:0003957	NAD(P)+ transhydrogenase (B-specific) activity	molecular_function	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.
GO:0003958	NADPH-hemoprotein reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.
GO:0003959	NADPH dehydrogenase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
GO:0003960	NADPH:quinone reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
GO:0003961	O-acetylhomoserine aminocarboxypropyltransferase activity	molecular_function	Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
GO:0003962	cystathionine gamma-synthase activity	molecular_function	Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.
GO:0003963	RNA-3'-phosphate cyclase activity	molecular_function	Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.
GO:0003964	RNA-directed DNA polymerase activity	molecular_function	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
GO:0003968	RNA-dependent RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
GO:0003972	RNA ligase (ATP) activity	molecular_function	Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).
GO:0003973	(S)-2-hydroxy-acid oxidase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.
GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.
GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity	molecular_function	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.
GO:0003978	UDP-glucose 4-epimerase activity	molecular_function	Catalysis of the reaction: UDP-glucose = UDP-galactose.
GO:0003979	UDP-glucose 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + 2 NAD+ + UDP-alpha-D-glucose = 3 H+ + 2 NADH + UDP-alpha-D-glucuronate.
GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity	molecular_function	Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.
GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
GO:0003984	acetolactate synthase activity	molecular_function	Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.
GO:0003985	acetyl-CoA C-acetyltransferase activity	molecular_function	Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.
GO:0003986	acetyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + H2O = acetate + CoA + H+.
GO:0003987	acetate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
GO:0003988	acetyl-CoA C-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
GO:0003989	acetyl-CoA carboxylase activity	molecular_function	Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
GO:0003990	acetylcholinesterase activity	molecular_function	Catalysis of the reaction: acetylcholine + H2O = choline + acetate.
GO:0003991	acetylglutamate kinase activity	molecular_function	Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.
GO:0003992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
GO:0003993	acid phosphatase activity	molecular_function	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
GO:0003994	aconitate hydratase activity	molecular_function	Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
GO:0003995	acyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: acyl-CoA + oxidized [electron-transfer flavoprotein]= 2,3-dehydroacyl-CoA + reduced [electron-transfer flavoprotein] + H+.
GO:0003997	acyl-CoA oxidase activity	molecular_function	Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.
GO:0003998	acylphosphatase activity	molecular_function	Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.
GO:0003999	adenine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0004000	adenosine deaminase activity	molecular_function	Catalysis of the reaction: adenosine + H2O = inosine + NH3.
GO:0004001	adenosine kinase activity	molecular_function	Catalysis of the reaction: ATP + adenosine = ADP + AMP.
GO:0004013	adenosylhomocysteinase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
GO:0004014	adenosylmethionine decarboxylase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2.
GO:0004015	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	molecular_function	Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate.
GO:0004016	adenylate cyclase activity	molecular_function	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
GO:0004017	adenylate kinase activity	molecular_function	Catalysis of the reaction: ATP + AMP = 2 ADP.
GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	molecular_function	Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
GO:0004019	adenylosuccinate synthase activity	molecular_function	Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H+ + phosphate.
GO:0004020	adenylylsulfate kinase activity	molecular_function	Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
GO:0004021	L-alanine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
GO:0004022	alcohol dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
GO:0004023	alcohol dehydrogenase activity, metal ion-independent	molecular_function	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion.
GO:0004024	alcohol dehydrogenase activity, zinc-dependent	molecular_function	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
GO:0004025	alcohol dehydrogenase activity, iron-dependent	molecular_function	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.
GO:0004026	alcohol O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.
GO:0004027	alcohol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
GO:0004029	aldehyde dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
GO:0004031	aldehyde oxidase activity	molecular_function	Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
GO:0004032	alditol:NADP+ 1-oxidoreductase activity	molecular_function	Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
GO:0004033	aldo-keto reductase (NADP) activity	molecular_function	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.
GO:0004034	aldose 1-epimerase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
GO:0004035	alkaline phosphatase activity	molecular_function	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
GO:0004037	allantoicase activity	molecular_function	Catalysis of the reaction: allantoate + H2O = (S)-ureidoglycolate + urea.
GO:0004038	allantoinase activity	molecular_function	Catalysis of the reaction: allantoin + H2O = allantoate.
GO:0004039	allophanate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 3 H+ + urea-1-carboxylate = 2 CO2 + 2 NH4.
GO:0004040	amidase activity	molecular_function	Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
GO:0004042	acetyl-CoA:L-glutamate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H+.
GO:0004043	L-aminoadipate-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
GO:0004044	amidophosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.
GO:0004045	aminoacyl-tRNA hydrolase activity	molecular_function	Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
GO:0004046	aminoacylase activity	molecular_function	Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
GO:0004047	aminomethyltransferase activity	molecular_function	Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
GO:0004048	anthranilate phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.
GO:0004049	anthranilate synthase activity	molecular_function	Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
GO:0004051	arachidonate 5-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
GO:0004052	arachidonate 12(S)-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
GO:0004053	arginase activity	molecular_function	Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
GO:0004054	arginine kinase activity	molecular_function	Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H+.
GO:0004055	argininosuccinate synthase activity	molecular_function	Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.
GO:0004056	argininosuccinate lyase activity	molecular_function	Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.
GO:0004057	arginyl-tRNA--protein transferase activity	molecular_function	Catalysis of the reaction: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = H+ + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg).
GO:0004058	aromatic-L-amino-acid decarboxylase activity	molecular_function	Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.
GO:0004059	aralkylamine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
GO:0004060	arylamine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
GO:0004061	arylformamidase activity	molecular_function	Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
GO:0004062	aryl sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
GO:0004063	aryldialkylphosphatase activity	molecular_function	Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.
GO:0004064	arylesterase activity	molecular_function	Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.
GO:0004065	arylsulfatase activity	molecular_function	Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.
GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.
GO:0004067	asparaginase activity	molecular_function	Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
GO:0004068	aspartate 1-decarboxylase activity	molecular_function	Catalysis of the reaction: L-aspartate = beta-alanine + CO2.
GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
GO:0004070	aspartate carbamoyltransferase activity	molecular_function	Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H+ + phosphate.
GO:0004071	aspartate-ammonia ligase activity	molecular_function	Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine.
GO:0004072	aspartate kinase activity	molecular_function	Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H+.
GO:0004073	aspartate-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP+ + phosphate = 4-phospho-L-aspartate + H+ + NADPH.
GO:0004074	biliverdin reductase (NAD(P)+) activity	molecular_function	Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
GO:0004075	biotin carboxylase activity	molecular_function	Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
GO:0004076	biotin synthase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H+.
GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).
GO:0004078	biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)).
GO:0004079	biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase).
GO:0004080	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)).
GO:0004081	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	molecular_function	Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
GO:0004082	bisphosphoglycerate mutase activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.
GO:0004084	branched-chain-amino-acid transaminase activity	molecular_function	Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
GO:0004085	butyryl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.
GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	molecular_function	Catalysis of the reaction: 2 ATP + hydrogencarbonate + NH4+ = 2 ADP + carbamoyl phosphate + 2 H+ + phosphate.
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
GO:0004089	carbonate dehydratase activity	molecular_function	Catalysis of the reaction: H2CO3 = CO2 + H2O.
GO:0004090	carbonyl reductase (NADPH) activity	molecular_function	Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
GO:0004092	carnitine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.
GO:0004095	carnitine O-palmitoyltransferase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
GO:0004096	catalase activity	molecular_function	Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
GO:0004097	catechol oxidase activity	molecular_function	Catalysis of the reaction: 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones.
GO:0004098	cerebroside-sulfatase activity	molecular_function	Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.
GO:0004099	chitin deacetylase activity	molecular_function	Catalysis of the reaction: chitin + H2O = chitosan + acetate.
GO:0004100	chitin synthase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
GO:0004102	choline O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.
GO:0004103	choline kinase activity	molecular_function	Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H+.
GO:0004104	cholinesterase activity	molecular_function	Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.
GO:0004105	choline-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.
GO:0004106	chorismate mutase activity	molecular_function	Catalysis of the reaction: chorismate = prephenate.
GO:0004107	chorismate synthase activity	molecular_function	Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
GO:0004108	citrate (Si)-synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.
GO:0004109	coproporphyrinogen oxidase activity	molecular_function	Catalysis of the reaction: coproporphyrinogen III + 2 H+ + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX.
GO:0004110	corticosteroid side-chain-isomerase activity	molecular_function	Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.
GO:0004111	creatine kinase activity	molecular_function	Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H+.
GO:0004112	cyclic-nucleotide phosphodiesterase activity	molecular_function	Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	molecular_function	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	molecular_function	Catalysis of the reaction: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate.
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	molecular_function	Catalysis of the reaction: 3',5'-cyclic AMP + H2O = AMP + H+.
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	molecular_function	Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	molecular_function	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.
GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	molecular_function	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.
GO:0004120	photoreceptor cyclic-nucleotide phosphodiesterase activity	molecular_function	Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.
GO:0004121	cystathionine beta-lyase activity	molecular_function	Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
GO:0004122	cystathionine beta-synthase activity	molecular_function	Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
GO:0004123	cystathionine gamma-lyase activity	molecular_function	Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
GO:0004124	cysteine synthase activity	molecular_function	Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
GO:0004125	L-seryl-tRNA(Sec) selenium transferase activity	molecular_function	Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.
GO:0004126	cytidine deaminase activity	molecular_function	Catalysis of the reaction: cytidine + H2O = uridine + NH3.
GO:0004127	cytidylate kinase activity	molecular_function	Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	molecular_function	Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).
GO:0004129	cytochrome-c oxidase activity	molecular_function	Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
GO:0004130	cytochrome-c peroxidase activity	molecular_function	Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.
GO:0004131	cytosine deaminase activity	molecular_function	Catalysis of the reaction: cytosine + H2O = uracil + NH3.
GO:0004132	dCMP deaminase activity	molecular_function	Catalysis of the reaction: dCMP + H2O = dUMP + NH3.
GO:0004133	glycogen debranching enzyme activity	molecular_function	Catalysis of the cleavage of branch points in branched glycogen polymers.
GO:0004134	4-alpha-glucanotransferase activity	molecular_function	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
GO:0004135	amylo-alpha-1,6-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.
GO:0004136	deoxyadenosine kinase activity	molecular_function	Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.
GO:0004137	deoxycytidine kinase activity	molecular_function	Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
GO:0004138	deoxyguanosine kinase activity	molecular_function	Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H+.
GO:0004139	deoxyribose-phosphate aldolase activity	molecular_function	Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
GO:0004140	dephospho-CoA kinase activity	molecular_function	Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+.
GO:0004141	dethiobiotin synthase activity	molecular_function	Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO2 = ADP + dethiobiotin + 4 H+ + phosphate.
GO:0004142	diacylglycerol cholinephosphotransferase activity	molecular_function	Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.
GO:0004143	ATP-dependent diacylglycerol kinase activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+.
GO:0004144	diacylglycerol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
GO:0004145	diamine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
GO:0004146	dihydrofolate reductase activity	molecular_function	Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
GO:0004148	dihydrolipoyl dehydrogenase activity	molecular_function	Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.
GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide.
GO:0004150	dihydroneopterin aldolase activity	molecular_function	Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.
GO:0004151	dihydroorotase activity	molecular_function	Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.
GO:0004152	dihydroorotate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
GO:0004153	dihydropterin deaminase activity	molecular_function	Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.
GO:0004154	dihydropterin oxidase activity	molecular_function	Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.
GO:0004155	6,7-dihydropteridine reductase activity	molecular_function	Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.
GO:0004156	dihydropteroate synthase activity	molecular_function	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.
GO:0004157	dihydropyrimidinase activity	molecular_function	Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.
GO:0004159	dihydropyrimidine dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.
GO:0004160	dihydroxy-acid dehydratase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
GO:0004161	dimethylallyltranstransferase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
GO:0004162	dimethylnitrosamine demethylase activity	molecular_function	Catalysis of the removal of a methyl group from N-nitrosodimethylamine.
GO:0004163	diphosphomevalonate decarboxylase activity	molecular_function	Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.
GO:0004164	diphthine synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
GO:0004165	delta(3)-delta(2)-enoyl-CoA isomerase activity	molecular_function	Catalysis of the reactions: a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA or a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.
GO:0004166	dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.
GO:0004167	dopachrome isomerase activity	molecular_function	Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
GO:0004168	dolichol kinase activity	molecular_function	Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.
GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity	molecular_function	Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
GO:0004170	dUTP diphosphatase activity	molecular_function	Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate.
GO:0004173	ecdysone O-acyltransferase activity	molecular_function	Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.
GO:0004174	electron-transferring-flavoprotein dehydrogenase activity	molecular_function	Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].
GO:0004175	endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0004176	ATP-dependent peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.
GO:0004177	aminopeptidase activity	molecular_function	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.
GO:0004180	carboxypeptidase activity	molecular_function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.
GO:0004181	metallocarboxypeptidase activity	molecular_function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0004185	serine-type carboxypeptidase activity	molecular_function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0004190	aspartic-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
GO:0004197	cysteine-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
GO:0004222	metalloendopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0004239	initiator methionyl aminopeptidase activity	molecular_function	Catalysis of the release of N-terminal initiator methionine from peptides.
GO:0004252	serine-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0004298	threonine-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
GO:0004300	enoyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a enoyl-CoA + H2O. This reaction usually occurs in the reverse direction, leading to the reduction of the double bound of enoyl-CoA in position 2 or 3. Specific reactions catalyzed include: a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O and a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O.
GO:0004301	epoxide hydrolase activity	molecular_function	Catalysis of the reaction: an epoxide + H2O = a glycol.
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	molecular_function	Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor.
GO:0004304	estrone sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.
GO:0004305	ethanolamine kinase activity	molecular_function	Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H+ + phosphoethanolamine.
GO:0004306	ethanolamine-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.
GO:0004307	ethanolaminephosphotransferase activity	molecular_function	Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
GO:0004308	exo-alpha-sialidase activity	molecular_function	Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
GO:0004309	exopolyphosphatase activity	molecular_function	Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.
GO:0004310	farnesyl-diphosphate farnesyltransferase activity	molecular_function	Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
GO:0004311	farnesyltranstransferase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
GO:0004312	fatty acid synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein].
GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].
GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].
GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.
GO:0004317	(3R)-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	molecular_function	Catalysis of the reaction: (3R)-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.
GO:0004318	enoyl-[acyl-carrier-protein] reductase (NADH) activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.
GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+.
GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity	molecular_function	Catalysis of the reaction: (9Z)-octadecenoyl-[ACP] + H2O = (9Z)-octadecenoate + H+ + holo-[ACP].
GO:0004321	fatty-acyl-CoA synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
GO:0004322	ferroxidase activity	molecular_function	Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
GO:0004324	ferredoxin-NADP+ reductase activity	molecular_function	Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.
GO:0004325	ferrochelatase activity	molecular_function	Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.
GO:0004326	tetrahydrofolylpolyglutamate synthase activity	molecular_function	Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).
GO:0004328	formamidase activity	molecular_function	Catalysis of the reaction: formamide + H2O = formate + NH4.
GO:0004329	formate-tetrahydrofolate ligase activity	molecular_function	Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity	molecular_function	Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.
GO:0004332	fructose-bisphosphate aldolase activity	molecular_function	Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
GO:0004333	fumarate hydratase activity	molecular_function	Catalysis of the reaction: (S)-malate = fumarate + H2O.
GO:0004334	fumarylacetoacetase activity	molecular_function	Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H+.
GO:0004335	galactokinase activity	molecular_function	Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H+.
GO:0004336	galactosylceramidase activity	molecular_function	Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
GO:0004337	geranyltranstransferase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
GO:0004338	glucan exo-1,3-beta-glucosidase activity	molecular_function	Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.
GO:0004339	glucan 1,4-alpha-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.
GO:0004340	glucokinase activity	molecular_function	Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
GO:0004341	gluconolactonase activity	molecular_function	Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.
GO:0004342	glucosamine-6-phosphate deaminase activity	molecular_function	Catalysis of the reaction: D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4.
GO:0004343	glucosamine 6-phosphate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H+.
GO:0004344	glucose dehydrogenase activity	molecular_function	Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.
GO:0004345	glucose-6-phosphate dehydrogenase activity	molecular_function	Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
GO:0004346	glucose-6-phosphatase activity	molecular_function	Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
GO:0004347	glucose-6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.
GO:0004348	glucosylceramidase activity	molecular_function	Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.
GO:0004349	glutamate 5-kinase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H+.
GO:0004350	glutamate-5-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP+ + phosphate = L-glutamyl 5-phosphate + H+ + NADPH.
GO:0004351	glutamate decarboxylase activity	molecular_function	Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.
GO:0004352	glutamate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.
GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.
GO:0004354	glutamate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
GO:0004355	glutamate synthase (NADPH) activity	molecular_function	Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.
GO:0004356	glutamine synthetase activity	molecular_function	Catalysis of the reaction: ATP + L-glutamate + NH4+ = ADP + H+ + L-glutamine + phosphate.
GO:0004357	glutamate-cysteine ligase activity	molecular_function	Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H+ + phosphate.
GO:0004358	glutamate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.
GO:0004359	glutaminase activity	molecular_function	Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	molecular_function	Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.
GO:0004361	glutaryl-CoA dehydrogenase activity	molecular_function	3-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein].
GO:0004362	glutathione-disulfide reductase (NADP) activity	molecular_function	Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
GO:0004363	glutathione synthase activity	molecular_function	Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate.
GO:0004364	glutathione transferase activity	molecular_function	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.
GO:0004366	glycerol-3-phosphate O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.
GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
GO:0004369	glycerol-3-phosphate oxidase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + O2 = glycerone phosphate + H2O2.
GO:0004370	glycerol kinase activity	molecular_function	Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H+.
GO:0004371	glycerone kinase activity	molecular_function	Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H+.
GO:0004372	glycine hydroxymethyltransferase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
GO:0004373	glycogen (starch) synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1).
GO:0004375	glycine dehydrogenase (decarboxylating) activity	molecular_function	Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.
GO:0004376	glycolipid mannosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
GO:0004377	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity	molecular_function	Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
GO:0004378	GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	molecular_function	Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.
GO:0004379	glycylpeptide N-tetradecanoyltransferase activity	molecular_function	Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.
GO:0004380	glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.
GO:0004381	fucosylgalactoside 3-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.
GO:0004382	GDP phosphatase activity	molecular_function	Catalysis of the reaction: GDP + H2O = GMP + phosphate.
GO:0004383	guanylate cyclase activity	molecular_function	Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
GO:0004385	guanylate kinase activity	molecular_function	Catalysis of the reaction: ATP + GMP = ADP + GDP.
GO:0004386	helicase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO:0004392	heme oxygenase (decyclizing) activity	molecular_function	Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].
GO:0004394	heparan sulfate 2-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.
GO:0004395	hexaprenyldihydroxybenzoate methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.
GO:0004396	hexokinase activity	molecular_function	Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.
GO:0004397	histidine ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-histidine = urocanate + NH3.
GO:0004398	histidine decarboxylase activity	molecular_function	Catalysis of the reaction: L-histidine = histamine + CO2.
GO:0004399	histidinol dehydrogenase activity	molecular_function	Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.
GO:0004400	histidinol-phosphate transaminase activity	molecular_function	Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
GO:0004401	histidinol-phosphatase activity	molecular_function	Catalysis of the reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate.
GO:0004402	histone acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
GO:0004407	histone deacetylase activity	molecular_function	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
GO:0004408	holocytochrome-c synthase activity	molecular_function	Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.
GO:0004409	homoaconitate hydratase activity	molecular_function	Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H2O.
GO:0004410	homocitrate synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H2O = CoA + H+ + homocitrate.
GO:0004411	homogentisate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate + H+.
GO:0004412	homoserine dehydrogenase activity	molecular_function	Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
GO:0004413	homoserine kinase activity	molecular_function	Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H+.
GO:0004414	homoserine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.
GO:0004415	hyalurononglucosaminidase activity	molecular_function	Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
GO:0004416	hydroxyacylglutathione hydrolase activity	molecular_function	Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
GO:0004417	hydroxyethylthiazole kinase activity	molecular_function	Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H+.
GO:0004418	hydroxymethylbilane synthase activity	molecular_function	Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4.
GO:0004419	hydroxymethylglutaryl-CoA lyase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.
GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.
GO:0004421	hydroxymethylglutaryl-CoA synthase activity	molecular_function	Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+.
GO:0004422	hypoxanthine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0004423	iduronate-2-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.
GO:0004424	imidazoleglycerol-phosphate dehydratase activity	molecular_function	Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O.
GO:0004425	indole-3-glycerol-phosphate synthase activity	molecular_function	Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.
GO:0004427	inorganic diphosphate phosphatase activity	molecular_function	Catalysis of the reaction: diphosphate + H2O = H+ + 2 phosphate.
GO:0004430	1-phosphatidylinositol 4-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H+.
GO:0004435	phosphatidylinositol phospholipase C activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+.
GO:0004436	phosphatidylinositol diacylglycerol-lyase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol.
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
GO:0004441	inositol-1,4-bisphosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
GO:0004445	inositol-polyphosphate 5-phosphatase activity	molecular_function	Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
GO:0004446	inositol-hexakisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.
GO:0004447	iodide peroxidase activity	molecular_function	Catalysis of the reaction: iodide + H2O2 = iodine + 2 H2O.
GO:0004448	isocitrate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.
GO:0004449	isocitrate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.
GO:0004450	isocitrate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.
GO:0004451	isocitrate lyase activity	molecular_function	Catalysis of the reaction: isocitrate = glyoxylate + succinate.
GO:0004452	isopentenyl-diphosphate delta-isomerase activity	molecular_function	Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
GO:0004453	juvenile-hormone esterase activity	molecular_function	Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.
GO:0004454	ketohexokinase activity	molecular_function	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
GO:0004455	ketol-acid reductoisomerase activity	molecular_function	Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
GO:0004456	phosphogluconate dehydratase activity	molecular_function	Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.
GO:0004457	lactate dehydrogenase activity	molecular_function	Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.
GO:0004458	D-lactate dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.
GO:0004459	L-lactate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
GO:0004460	L-lactate dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.
GO:0004461	lactose synthase activity	molecular_function	Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.
GO:0004462	lactoylglutathione lyase activity	molecular_function	Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
GO:0004463	leukotriene-A4 hydrolase activity	molecular_function	Catalysis of the reaction: H2O + leukotriene A(4) = leukotriene B(4).
GO:0004464	leukotriene-C4 synthase activity	molecular_function	Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).
GO:0004465	lipoprotein lipase activity	molecular_function	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein.
GO:0004466	long-chain-acyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].
GO:0004467	long-chain fatty acid-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	molecular_function	Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.
GO:0004470	malic enzyme activity	molecular_function	Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	molecular_function	Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.
GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity	molecular_function	Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
GO:0004474	malate synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H+.
GO:0004475	mannose-1-phosphate guanylyltransferase (GTP) activity	molecular_function	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.
GO:0004476	mannose-6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	molecular_function	Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.
GO:0004478	methionine adenosyltransferase activity	molecular_function	Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
GO:0004479	methionyl-tRNA formyltransferase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.
GO:0004481	methylene-fatty-acyl-phospholipid synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid.
GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.
GO:0004484	mRNA guanylyltransferase activity	molecular_function	Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
GO:0004485	methylcrotonoyl-CoA carboxylase activity	molecular_function	Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H+ + phosphate.
GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.
GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH.
GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH.
GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
GO:0004490	methylglutaconyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H2O.
GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity	molecular_function	Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product.
GO:0004492	methyl/ethyl malonyl-CoA decarboxylase activity	molecular_function	Catalysis of the reaction: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA or (2S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2.
GO:0004493	methylmalonyl-CoA epimerase activity	molecular_function	Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.
GO:0004494	methylmalonyl-CoA mutase activity	molecular_function	Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.
GO:0004495	mevaldate reductase activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor.
GO:0004496	mevalonate kinase activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H+.
GO:0004497	monooxygenase activity	molecular_function	Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO:0004498	calcidiol 1-monooxygenase activity	molecular_function	Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+.
GO:0004499	N,N-dimethylaniline monooxygenase activity	molecular_function	Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
GO:0004500	dopamine beta-monooxygenase activity	molecular_function	Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O.
GO:0004501	ecdysone 20-monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + Ecdysone + O2 = 20-hydroxyecdysone + A + H2O.
GO:0004502	kynurenine 3-monooxygenase activity	molecular_function	Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+.
GO:0004503	tyrosinase activity	molecular_function	Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.
GO:0004504	peptidylglycine monooxygenase activity	molecular_function	Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
GO:0004505	phenylalanine 4-monooxygenase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
GO:0004506	squalene monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+.
GO:0004507	steroid 11-beta-monooxygenase activity	molecular_function	Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.
GO:0004508	steroid 17-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.
GO:0004509	steroid 21-monooxygenase activity	molecular_function	Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O.
GO:0004510	tryptophan 5-monooxygenase activity	molecular_function	Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
GO:0004511	tyrosine 3-monooxygenase activity	molecular_function	Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
GO:0004512	inositol-3-phosphate synthase activity	molecular_function	Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	molecular_function	Catalysis of the reaction: CO2 + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H+ + quinolinate.
GO:0004515	nicotinate-nucleotide adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
GO:0004516	nicotinate phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H+ + nicotinate.
GO:0004517	nitric-oxide synthase activity	molecular_function	Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
GO:0004518	nuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids.
GO:0004519	endonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
GO:0004520	DNA endonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0004521	RNA endonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0004522	ribonuclease A activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
GO:0004523	RNA-DNA hybrid ribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
GO:0004525	ribonuclease III activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
GO:0004526	ribonuclease P activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
GO:0004527	exonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.
GO:0004528	phosphodiesterase I activity	molecular_function	Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
GO:0004529	DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.
GO:0004530	deoxyribonuclease I activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
GO:0004531	deoxyribonuclease II activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products.
GO:0004532	RNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.
GO:0004533	exoribonuclease H activity	molecular_function	Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
GO:0004534	5'-3' RNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
GO:0004535	poly(A)-specific ribonuclease activity	molecular_function	Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
GO:0004536	DNA nuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0004540	RNA nuclease activity	molecular_function	Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0004549	tRNA-specific ribonuclease activity	molecular_function	Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
GO:0004550	nucleoside diphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
GO:0004551	dinucleotide phosphatase activity	molecular_function	Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.
GO:0004552	octanol dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-octanol + NAD+ = 1-octanal + H+ + NADH.
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	molecular_function	Catalysis of the hydrolysis of any O-glycosyl bond.
GO:0004555	alpha,alpha-trehalase activity	molecular_function	Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
GO:0004556	alpha-amylase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
GO:0004557	alpha-galactosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.
GO:0004558	alpha-1,4-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
GO:0004559	alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
GO:0004560	alpha-L-fucosidase activity	molecular_function	Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.
GO:0004561	alpha-N-acetylglucosaminidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.
GO:0004563	beta-N-acetylhexosaminidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
GO:0004564	beta-fructofuranosidase activity	molecular_function	Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.
GO:0004565	beta-galactosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
GO:0004566	beta-glucuronidase activity	molecular_function	Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.
GO:0004567	beta-mannosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.
GO:0004568	chitinase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
GO:0004569	glycoprotein endo-alpha-1,2-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.
GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
GO:0004572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
GO:0004573	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity	molecular_function	Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
GO:0004574	oligo-1,6-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.
GO:0004575	sucrose alpha-glucosidase activity	molecular_function	Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.
GO:0004576	oligosaccharyl transferase activity	molecular_function	Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0004577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.
GO:0004578	chitobiosyldiphosphodolichol beta-mannosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol.
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	molecular_function	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
GO:0004581	dolichyl-phosphate beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.
GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.
GO:0004585	ornithine carbamoyltransferase activity	molecular_function	Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
GO:0004586	ornithine decarboxylase activity	molecular_function	Catalysis of the reaction: L-ornithine + H+ = CO2 + putrescine.
GO:0004587	ornithine-oxo-acid transaminase activity	molecular_function	Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
GO:0004588	orotate phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0004589	dihydroorotate dehydrogenase (NADH) activity	molecular_function	Catalysis of the reaction: (S)-dihydroorotate + NAD+ = H+ + NADH + orotate.
GO:0004590	orotidine-5'-phosphate decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + orotidine 5'-phosphate = CO2 + UMP.
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + lipoamide + H+ = S-succinyldihydrolipoamide + CO2.
GO:0004592	pantoate-beta-alanine ligase activity	molecular_function	Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
GO:0004593	pantothenase activity	molecular_function	Catalysis of the reaction: (R)-pantothenate + H2O = (R)-pantoate + beta-alanine.
GO:0004594	pantothenate kinase activity	molecular_function	Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.
GO:0004595	pantetheine-phosphate adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.
GO:0004596	peptide alpha-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
GO:0004598	peptidylamidoglycolate lyase activity	molecular_function	Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.
GO:0004601	peroxidase activity	molecular_function	Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.
GO:0004602	glutathione peroxidase activity	molecular_function	Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
GO:0004603	phenylethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.
GO:0004604	phosphoadenylyl-sulfate reductase (thioredoxin) activity	molecular_function	Catalysis of the reaction: adenosine 3',5'-diphosphate + H+ + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
GO:0004605	phosphatidate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.
GO:0004608	phosphatidylethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.
GO:0004609	phosphatidylserine decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + phosphatidyl-L-serine = CO2 + phosphatidylethanolamine.
GO:0004610	phosphoacetylglucosamine mutase activity	molecular_function	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.
GO:0004611	phosphoenolpyruvate carboxykinase activity	molecular_function	Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.
GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	molecular_function	Catalysis of the reaction: ATP + oxaloacetate = ADP + CO2 + H+ + phosphoenolpyruvate.
GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	molecular_function	Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.
GO:0004614	phosphoglucomutase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
GO:0004615	phosphomannomutase activity	molecular_function	Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	molecular_function	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
GO:0004617	phosphoglycerate dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.
GO:0004618	phosphoglycerate kinase activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H+.
GO:0004619	phosphoglycerate mutase activity	molecular_function	Catalysis of the reaction: 2-phosphoglycerate = 3-phosphoglycerate.
GO:0004620	phospholipase activity	molecular_function	Catalysis of the hydrolysis of a glycerophospholipid.
GO:0004621	glycosylphosphatidylinositol phospholipase D activity	molecular_function	Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.
GO:0004622	lysophospholipase activity	molecular_function	Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
GO:0004623	phospholipase A2 activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.
GO:0004629	phospholipase C activity	molecular_function	Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
GO:0004630	phospholipase D activity	molecular_function	Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
GO:0004631	phosphomevalonate kinase activity	molecular_function	Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H+.
GO:0004632	phosphopantothenate--cysteine ligase activity	molecular_function	Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.
GO:0004633	phosphopantothenoylcysteine decarboxylase activity	molecular_function	Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H+ = CO2 + pantetheine 4'-phosphate.
GO:0004634	phosphopyruvate hydratase activity	molecular_function	Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	molecular_function	Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H2O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.
GO:0004636	phosphoribosyl-ATP diphosphatase activity	molecular_function	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H2O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H+.
GO:0004637	phosphoribosylamine-glycine ligase activity	molecular_function	Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.
GO:0004638	phosphoribosylaminoimidazole carboxylase activity	molecular_function	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2.
GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	molecular_function	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H+ + phosphate.
GO:0004640	phosphoribosylanthranilate isomerase activity	molecular_function	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	molecular_function	Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H+ + phosphate.
GO:0004642	phosphoribosylformylglycinamidine synthase activity	molecular_function	Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H+ + phosphate.
GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.
GO:0004644	phosphoribosylglycinamide formyltransferase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.
GO:0004645	1,4-alpha-oligoglucan phosphorylase activity	molecular_function	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
GO:0004648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
GO:0004649	poly(ADP-ribose) glycohydrolase activity	molecular_function	Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.
GO:0004650	polygalacturonase activity	molecular_function	Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
GO:0004651	polynucleotide 5'-phosphatase activity	molecular_function	Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
GO:0004654	polyribonucleotide nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
GO:0004655	porphobilinogen synthase activity	molecular_function	Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.
GO:0004656	procollagen-proline 4-dioxygenase activity	molecular_function	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
GO:0004657	proline dehydrogenase activity	molecular_function	Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor.
GO:0004658	propionyl-CoA carboxylase activity	molecular_function	Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.
GO:0004659	prenyltransferase activity	molecular_function	Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).
GO:0004660	protein farnesyltransferase activity	molecular_function	Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
GO:0004661	protein geranylgeranyltransferase activity	molecular_function	Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.
GO:0004662	CAAX-protein geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families.
GO:0004663	Rab geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.
GO:0004664	prephenate dehydratase activity	molecular_function	Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.
GO:0004665	prephenate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADPH.
GO:0004666	prostaglandin-endoperoxide synthase activity	molecular_function	Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
GO:0004667	prostaglandin-D synthase activity	molecular_function	Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
GO:0004668	protein-arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent.
GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.
GO:0004672	protein kinase activity	molecular_function	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0004673	protein histidine kinase activity	molecular_function	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
GO:0004674	protein serine/threonine kinase activity	molecular_function	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	molecular_function	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0004676	3-phosphoinositide-dependent protein kinase activity	molecular_function	Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004677	DNA-dependent protein kinase activity	molecular_function	DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004679	AMP-activated protein kinase activity	molecular_function	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.
GO:0004683	calmodulin-dependent protein kinase activity	molecular_function	Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
GO:0004686	elongation factor-2 kinase activity	molecular_function	Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.
GO:0004687	myosin light chain kinase activity	molecular_function	Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
GO:0004689	phosphorylase kinase activity	molecular_function	Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.
GO:0004690	cyclic nucleotide-dependent protein kinase activity	molecular_function	cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004691	cAMP-dependent protein kinase activity	molecular_function	cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004692	cGMP-dependent protein kinase activity	molecular_function	cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	molecular_function	Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	molecular_function	Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.
GO:0004697	protein kinase C activity	molecular_function	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
GO:0004698	calcium-dependent protein kinase C activity	molecular_function	Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0004699	calcium-independent protein kinase C activity	molecular_function	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium.
GO:0004703	G protein-coupled receptor kinase activity	molecular_function	Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.
GO:0004704	NF-kappaB-inducing kinase activity	molecular_function	Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).
GO:0004705	JUN kinase activity	molecular_function	Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.
GO:0004706	JUN kinase kinase kinase activity	molecular_function	Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).
GO:0004707	MAP kinase activity	molecular_function	Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
GO:0004708	MAP kinase kinase activity	molecular_function	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.
GO:0004709	MAP kinase kinase kinase activity	molecular_function	Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
GO:0004711	ribosomal protein S6 kinase activity	molecular_function	Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.
GO:0004712	protein serine/threonine/tyrosine kinase activity	molecular_function	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
GO:0004713	protein tyrosine kinase activity	molecular_function	Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
GO:0004714	transmembrane receptor protein tyrosine kinase activity	molecular_function	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
GO:0004715	non-membrane spanning protein tyrosine kinase activity	molecular_function	Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.
GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.
GO:0004720	protein-lysine 6-oxidase activity	molecular_function	Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.
GO:0004721	phosphoprotein phosphatase activity	molecular_function	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0004722	protein serine/threonine phosphatase activity	molecular_function	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	molecular_function	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
GO:0004725	protein tyrosine phosphatase activity	molecular_function	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	molecular_function	Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.
GO:0004727	prenylated protein tyrosine phosphatase activity	molecular_function	Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.
GO:0004729	oxygen-dependent protoporphyrinogen oxidase activity	molecular_function	Catalysis of the reaction: 3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX.
GO:0004730	pseudouridylate synthase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + uracil = H2O + pseudouridine 5'-phosphate.
GO:0004731	purine-nucleoside phosphorylase activity	molecular_function	Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
GO:0004732	pyridoxal oxidase activity	molecular_function	Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.
GO:0004733	pyridoxamine phosphate oxidase activity	molecular_function	Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH4+ + hydrogen peroxide. This activity can also oxidize pyridoxine 5'-phosphate to  pyridoxal 5'-phosphate + hydrogen peroxide.
GO:0004734	pyrimidodiazepine synthase activity	molecular_function	Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.
GO:0004735	pyrroline-5-carboxylate reductase activity	molecular_function	Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.
GO:0004736	pyruvate carboxylase activity	molecular_function	Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H+ + oxaloacetate + phosphate.
GO:0004737	pyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
GO:0004738	pyruvate dehydrogenase activity	molecular_function	Catalysis of the oxidative decarboxylation of pyruvate.
GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity	molecular_function	Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.
GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	molecular_function	Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.
GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity	molecular_function	Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.
GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	molecular_function	Catalysis of the reaction: (R)-N6-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N6-(S8-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA.
GO:0004743	pyruvate kinase activity	molecular_function	Catalysis of the reaction: = ADP + H+ + phosphoenolpyruvate => ATP + pyruvate.
GO:0004745	NAD-retinol dehydrogenase activity	molecular_function	Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
GO:0004746	riboflavin synthase activity	molecular_function	Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ = 5-amino-6-(D-ribitylamino)uracil + riboflavin.
GO:0004747	ribokinase activity	molecular_function	Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	molecular_function	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0004749	ribose phosphate diphosphokinase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H+.
GO:0004750	D-ribulose-phosphate 3-epimerase activity	molecular_function	Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate.
GO:0004751	ribose-5-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate.
GO:0004753	saccharopine dehydrogenase activity	molecular_function	Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.
GO:0004754	saccharopine dehydrogenase (NAD+, L-lysine-forming) activity	molecular_function	Catalysis of the reaction: L-saccharopine + H2O + NAD+ = 2-oxoglutarate + L-lysine + H+ + NADH.
GO:0004755	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity	molecular_function	Catalysis of the reaction: L-saccharopine + H2O + NADP+ = L-allysine + L-glutamate + H+ + NADPH.
GO:0004756	selenide, water dikinase activity	molecular_function	Catalysis of the reaction: ATP + H2O + hydrogen selenide = AMP + 3 H+ + phosphate + selenophosphorate.
GO:0004757	sepiapterin reductase activity	molecular_function	Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+.
GO:0004758	serine C-palmitoyltransferase activity	molecular_function	Catalysis of the reaction: L-serine + H+ + palmitoyl-CoA = 3-dehydrosphinganine + CO2 + CoA.
GO:0004760	serine-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
GO:0004764	shikimate 3-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
GO:0004765	shikimate kinase activity	molecular_function	Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H+.
GO:0004766	spermidine synthase activity	molecular_function	Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
GO:0004767	sphingomyelin phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+.
GO:0004768	stearoyl-CoA 9-desaturase activity	molecular_function	Catalysis of the reaction: 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.
GO:0004769	steroid delta-isomerase activity	molecular_function	Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.
GO:0004771	sterol esterase activity	molecular_function	Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.
GO:0004772	sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester.
GO:0004773	steryl-sulfatase activity	molecular_function	Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.
GO:0004774	succinate-CoA ligase activity	molecular_function	Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.
GO:0004775	succinate-CoA ligase (ADP-forming) activity	molecular_function	Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.
GO:0004776	succinate-CoA ligase (GDP-forming) activity	molecular_function	Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.
GO:0004777	succinate-semialdehyde dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
GO:0004778	succinyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + succinyl-CoA = CoA + H+ + succinate.
GO:0004779	sulfate adenylyltransferase activity	molecular_function	Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate.
GO:0004780	sulfate adenylyltransferase (ADP) activity	molecular_function	Catalysis of the reaction: ADP + H+ + sulfate = 5'-adenylyl sulfate + phosphate.
GO:0004781	sulfate adenylyltransferase (ATP) activity	molecular_function	Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
GO:0004782	sulfinoalanine decarboxylase activity	molecular_function	Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.
GO:0004783	sulfite reductase (NADPH) activity	molecular_function	Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.
GO:0004784	superoxide dismutase activity	molecular_function	Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
GO:0004787	thiamine diphosphate phosphatase activity	molecular_function	Catalysis of the reaction: thiamine diphosphate + H2O = thiamine monophosphate + phosphate.
GO:0004788	thiamine diphosphokinase activity	molecular_function	Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.
GO:0004789	thiamine-phosphate diphosphorylase activity	molecular_function	Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H+ = diphosphate + thiamine phosphate.
GO:0004790	thioether S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.
GO:0004791	thioredoxin-disulfide reductase (NADP) activity	molecular_function	Catalysis of the reaction: thioredoxin-dithiol + NADP+ = thioredoxin-disulfide + H+ + NADPH.
GO:0004792	thiosulfate sulfurtransferase activity	molecular_function	Catalysis of the reaction: hydrogen cyanide + thiosulfate = H+ + sulfite + thiocyanate.
GO:0004793	threonine aldolase activity	molecular_function	Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
GO:0004794	L-threonine ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3.
GO:0004795	threonine synthase activity	molecular_function	Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.
GO:0004796	thromboxane-A synthase activity	molecular_function	Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).
GO:0004797	thymidine kinase activity	molecular_function	Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
GO:0004798	thymidylate kinase activity	molecular_function	Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
GO:0004799	thymidylate synthase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
GO:0004800	thyroxine 5'-deiodinase activity	molecular_function	Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
GO:0004801	transaldolase activity	molecular_function	Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
GO:0004802	transketolase activity	molecular_function	Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.
GO:0004803	transposase activity	molecular_function	Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.
GO:0004805	trehalose-phosphatase activity	molecular_function	Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.
GO:0004806	triglyceride lipase activity	molecular_function	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
GO:0004807	triose-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
GO:0004808	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.
GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine.
GO:0004810	CCA tRNA nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate.
GO:0004812	aminoacyl-tRNA ligase activity	molecular_function	Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
GO:0004813	alanine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
GO:0004814	arginine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
GO:0004815	aspartate-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).
GO:0004816	asparagine-tRNA ligase activity	molecular_function	Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.
GO:0004817	cysteine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
GO:0004818	glutamate-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
GO:0004819	glutamine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).
GO:0004820	glycine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
GO:0004821	histidine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).
GO:0004822	isoleucine-tRNA ligase activity	molecular_function	Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H+.
GO:0004823	leucine-tRNA ligase activity	molecular_function	Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H+ + Leu-tRNA(Leu).
GO:0004824	lysine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
GO:0004825	methionine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).
GO:0004826	phenylalanine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
GO:0004827	proline-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
GO:0004828	serine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
GO:0004829	threonine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
GO:0004830	tryptophan-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).
GO:0004831	tyrosine-tRNA ligase activity	molecular_function	Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+.
GO:0004832	valine-tRNA ligase activity	molecular_function	Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H+.
GO:0004833	tryptophan 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
GO:0004834	tryptophan synthase activity	molecular_function	Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
GO:0004835	tubulin-tyrosine ligase activity	molecular_function	Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.
GO:0004836	tyramine-beta hydroxylase activity	molecular_function	Catalysis of the hydroxylation of tyramine to form octopamine.
GO:0004837	tyrosine decarboxylase activity	molecular_function	Catalysis of the reaction: L-tyrosine = tyramine + CO2.
GO:0004838	L-tyrosine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
GO:0004839	ubiquitin activating enzyme activity	molecular_function	Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
GO:0004842	ubiquitin-protein transferase activity	molecular_function	Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
GO:0004843	cysteine-type deubiquitinase activity	molecular_function	An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
GO:0004844	uracil DNA N-glycosylase activity	molecular_function	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
GO:0004845	uracil phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.
GO:0004846	urate oxidase activity	molecular_function	Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide.
GO:0004847	urea carboxylase activity	molecular_function	Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H+ + phosphate + urea-1-carboxylate.
GO:0004848	ureidoglycolate hydrolase activity	molecular_function	Catalysis of the reaction: (S)-ureidoglycolate + H2O + 2 H+ = CO2 + glyoxylate + 2 NH4.
GO:0004849	uridine kinase activity	molecular_function	Catalysis of the reaction: ATP + uridine = ADP + UMP.
GO:0004850	uridine phosphorylase activity	molecular_function	Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
GO:0004851	uroporphyrin-III C-methyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.
GO:0004852	uroporphyrinogen-III synthase activity	molecular_function	Catalysis of the reaction: hydroxymethylbilane = H2O + uroporphyrinogen III.
GO:0004853	uroporphyrinogen decarboxylase activity	molecular_function	Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.
GO:0004854	xanthine dehydrogenase activity	molecular_function	Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.
GO:0004855	xanthine oxidase activity	molecular_function	Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide.
GO:0004856	xylulokinase activity	molecular_function	Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H+.
GO:0004857	enzyme inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0004858	dUTP pyrophosphatase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of dUTP pyrophosphatase.
GO:0004859	phospholipase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.
GO:0004860	protein kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a protein kinase.
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
GO:0004862	cAMP-dependent protein kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
GO:0004864	protein phosphatase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a protein phosphatase.
GO:0004865	protein serine/threonine phosphatase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
GO:0004866	endopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of an endopeptidase.
GO:0004867	serine-type endopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a serine-type endopeptidase.
GO:0004869	cysteine-type endopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase.
GO:0004873	asialoglycoprotein receptor activity	molecular_function	Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane.
GO:0004875	complement receptor activity	molecular_function	Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004876	complement component C3a receptor activity	molecular_function	Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004877	complement component C3b receptor activity	molecular_function	Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004878	complement component C5a receptor activity	molecular_function	Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004879	nuclear receptor activity	molecular_function	A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.
GO:0004883	nuclear glucocorticoid receptor activity	molecular_function	Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
GO:0004888	transmembrane signaling receptor activity	molecular_function	Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
GO:0004890	GABA-A receptor activity	molecular_function	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
GO:0004895	cell adhesion receptor activity	molecular_function	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins.
GO:0004896	cytokine receptor activity	molecular_function	Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004897	ciliary neurotrophic factor receptor activity	molecular_function	Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004900	erythropoietin receptor activity	molecular_function	Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004901	granulocyte macrophage colony-stimulating factor receptor activity	molecular_function	Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004902	granulocyte colony-stimulating factor receptor activity	molecular_function	Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004903	growth hormone receptor activity	molecular_function	Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004904	interferon receptor activity	molecular_function	Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004905	type I interferon receptor activity	molecular_function	Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.
GO:0004906	type II interferon receptor activity	molecular_function	Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004908	interleukin-1 receptor activity	molecular_function	Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
GO:0004909	interleukin-1, type I, activating receptor activity	molecular_function	Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins.
GO:0004910	interleukin-1, type II, blocking receptor activity	molecular_function	Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors.
GO:0004911	interleukin-2 receptor activity	molecular_function	Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004912	interleukin-3 receptor activity	molecular_function	Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004913	interleukin-4 receptor activity	molecular_function	Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004914	interleukin-5 receptor activity	molecular_function	Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004915	interleukin-6 receptor activity	molecular_function	Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004917	interleukin-7 receptor activity	molecular_function	Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004918	interleukin-8 receptor activity	molecular_function	Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004919	interleukin-9 receptor activity	molecular_function	Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004920	interleukin-10 receptor activity	molecular_function	Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004921	interleukin-11 receptor activity	molecular_function	Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004923	leukemia inhibitory factor receptor activity	molecular_function	Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004924	oncostatin-M receptor activity	molecular_function	Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004925	prolactin receptor activity	molecular_function	Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0004930	G protein-coupled receptor activity	molecular_function	Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
GO:0004932	mating-type factor pheromone receptor activity	molecular_function	Combining with a mating-type factor pheromone to initiate a change in cell activity.
GO:0004933	mating-type a-factor pheromone receptor activity	molecular_function	Combining with the mating-type a-factor pheromone to initiate a change in cell activity.
GO:0004934	mating-type alpha-factor pheromone receptor activity	molecular_function	Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.
GO:0004935	adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.
GO:0004936	alpha-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.
GO:0004937	alpha1-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.
GO:0004938	alpha2-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.
GO:0004939	beta-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.
GO:0004940	beta1-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.
GO:0004941	beta2-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.
GO:0004945	angiotensin type II receptor activity	molecular_function	An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.
GO:0004946	bombesin receptor activity	molecular_function	Combining with bombesin to initiate a change in cell activity.
GO:0004947	bradykinin receptor activity	molecular_function	Combining with bradykinin to initiate a change in cell activity.
GO:0004948	calcitonin receptor activity	molecular_function	Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0004949	cannabinoid receptor activity	molecular_function	Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
GO:0004950	chemokine receptor activity	molecular_function	Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0004951	cholecystokinin receptor activity	molecular_function	Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.
GO:0004952	dopamine neurotransmitter receptor activity	molecular_function	Combining with the neurotransmitter dopamine to initiate a change in cell activity.
GO:0004953	icosanoid receptor activity	molecular_function	Combining with an icosanoid to initiate a change in cell activity.
GO:0004954	prostanoid receptor activity	molecular_function	Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity.
GO:0004955	prostaglandin receptor activity	molecular_function	Combining with a prostaglandin (PG) to initiate a change in cell activity.
GO:0004956	prostaglandin D receptor activity	molecular_function	Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.
GO:0004957	prostaglandin E receptor activity	molecular_function	Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.
GO:0004958	prostaglandin F receptor activity	molecular_function	Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.
GO:0004960	thromboxane receptor activity	molecular_function	Combining with a thromboxane (TXA) to initiate a change in cell activity.
GO:0004961	thromboxane A2 receptor activity	molecular_function	Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.
GO:0004962	endothelin receptor activity	molecular_function	Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0004963	follicle-stimulating hormone receptor activity	molecular_function	Combining with follicle-stimulating hormone to initiate a change in cell activity.
GO:0004964	luteinizing hormone receptor activity	molecular_function	Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.
GO:0004965	G protein-coupled GABA receptor activity	molecular_function	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0004966	galanin receptor activity	molecular_function	Combining with galanin to initiate a change in cell activity.
GO:0004967	glucagon receptor activity	molecular_function	Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0004968	gonadotropin-releasing hormone receptor activity	molecular_function	Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
GO:0004969	histamine receptor activity	molecular_function	Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0004970	ionotropic glutamate receptor activity	molecular_function	Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
GO:0004971	AMPA glutamate receptor activity	molecular_function	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
GO:0004972	NMDA glutamate receptor activity	molecular_function	An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.
GO:0004974	leukotriene receptor activity	molecular_function	Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine.
GO:0004977	melanocortin receptor activity	molecular_function	Combining with melanocortin to initiate a change in cell activity.
GO:0004978	corticotropin receptor activity	molecular_function	Combining with corticotropin to initiate a change in cell activity.
GO:0004979	beta-endorphin receptor activity	molecular_function	Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).
GO:0004980	melanocyte-stimulating hormone receptor activity	molecular_function	Combining with melanocyte-stimulating hormone to initiate a change in cell activity.
GO:0004982	N-formyl peptide receptor activity	molecular_function	Combining with an N-formyl peptide to initiate a change in cell activity.
GO:0004983	neuropeptide Y receptor activity	molecular_function	Combining with neuropeptide Y to initiate a change in cell activity.
GO:0004984	olfactory receptor activity	molecular_function	Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.
GO:0004985	G protein-coupled opioid receptor activity	molecular_function	Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.
GO:0004989	octopamine receptor activity	molecular_function	Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.
GO:0004990	oxytocin receptor activity	molecular_function	Combining with oxytocin to initiate a change in cell activity.
GO:0004991	parathyroid hormone receptor activity	molecular_function	Combining with parathyroid hormone to initiate a change in cell activity.
GO:0004992	platelet activating factor receptor activity	molecular_function	Combining with platelet activating factor to initiate a change in cell activity.
GO:0004993	G protein-coupled serotonin receptor activity	molecular_function	Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
GO:0004994	somatostatin receptor activity	molecular_function	Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).
GO:0004995	tachykinin receptor activity	molecular_function	Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.
GO:0004996	thyroid-stimulating hormone receptor activity	molecular_function	Combining with thyroid-stimulating hormone to initiate a change in cell activity.
GO:0004997	thyrotropin-releasing hormone receptor activity	molecular_function	Combining with thyrotropin-releasing hormone to initiate a change in cell activity.
GO:0004998	transferrin receptor activity	molecular_function	Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.
GO:0004999	vasoactive intestinal polypeptide receptor activity	molecular_function	Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.
GO:0005000	vasopressin receptor activity	molecular_function	Combining with vasopressin to initiate a change in cell activity.
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	molecular_function	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
GO:0005003	ephrin receptor activity	molecular_function	Combining with an ephrin receptor ligand to initiate a change in cell activity.
GO:0005004	GPI-linked ephrin receptor activity	molecular_function	Combining with a GPI-anchored ephrin to initiate a change in cell activity.
GO:0005005	transmembrane-ephrin receptor activity	molecular_function	Combining with a transmembrane ephrin to initiate a change in cell activity.
GO:0005006	epidermal growth factor receptor activity	molecular_function	Combining with an epidermal growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005007	fibroblast growth factor receptor activity	molecular_function	Combining with a fibroblast growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005008	hepatocyte growth factor receptor activity	molecular_function	Combining with hepatocyte growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005009	insulin receptor activity	molecular_function	Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005010	insulin-like growth factor receptor activity	molecular_function	Combining with insulin-like growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005011	macrophage colony-stimulating factor receptor activity	molecular_function	Combining with macrophage colony-stimulating factor (M-CSF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
GO:0005017	platelet-derived growth factor receptor activity	molecular_function	Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005018	platelet-derived growth factor alpha-receptor activity	molecular_function	Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.
GO:0005019	platelet-derived growth factor beta-receptor activity	molecular_function	Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.
GO:0005020	stem cell factor receptor activity	molecular_function	Combining with stem cell factor (SCF) receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.
GO:0005021	vascular endothelial growth factor receptor activity	molecular_function	Combining with a vascular endothelial growth factor (VEGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0005024	transforming growth factor beta receptor activity	molecular_function	Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0005025	transforming growth factor beta receptor activity, type I	molecular_function	Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.
GO:0005026	transforming growth factor beta receptor activity, type II	molecular_function	Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor.
GO:0005030	neurotrophin receptor activity	molecular_function	Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.
GO:0005031	tumor necrosis factor receptor activity	molecular_function	Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
GO:0005034	osmosensor activity	molecular_function	Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.
GO:0005035	death receptor activity	molecular_function	Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.
GO:0005041	low-density lipoprotein particle receptor activity	molecular_function	Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
GO:0005042	netrin receptor activity	molecular_function	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0005043	netrin receptor activity involved in chemorepulsion	molecular_function	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.
GO:0005044	scavenger receptor activity	molecular_function	Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
GO:0005046	KDEL sequence binding	molecular_function	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
GO:0005047	signal recognition particle binding	molecular_function	Binding to a signal recognition particle.
GO:0005048	signal sequence binding	molecular_function	Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.
GO:0005049	nuclear export signal receptor activity	molecular_function	Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
GO:0005052	peroxisome matrix targeting signal-1 binding	molecular_function	Binding to a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L.
GO:0005053	peroxisome matrix targeting signal-2 binding	molecular_function	Binding to a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F).
GO:0005055	laminin receptor activity	molecular_function	Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity.
GO:0005056	tiggrin receptor activity	molecular_function	Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	molecular_function	The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.
GO:0005078	MAP-kinase scaffold activity	molecular_function	The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
GO:0005080	protein kinase C binding	molecular_function	Binding to protein kinase C.
GO:0005085	guanyl-nucleotide exchange factor activity	molecular_function	Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
GO:0005091	guanyl-nucleotide exchange factor adaptor activity	molecular_function	The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.
GO:0005092	GDP-dissociation inhibitor activity	molecular_function	Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
GO:0005093	Rab GDP-dissociation inhibitor activity	molecular_function	Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.
GO:0005094	Rho GDP-dissociation inhibitor activity	molecular_function	Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
GO:0005095	GTPase inhibitor activity	molecular_function	Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.
GO:0005096	GTPase activator activity	molecular_function	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
GO:0005102	signaling receptor binding	molecular_function	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0005104	fibroblast growth factor receptor binding	molecular_function	Binding to a fibroblast growth factor receptor (FGFR).
GO:0005105	type 1 fibroblast growth factor receptor binding	molecular_function	Binding to a type 1 fibroblast growth factor receptor (FGFR1).
GO:0005109	frizzled binding	molecular_function	Binding to a frizzled (fz) receptor.
GO:0005111	type 2 fibroblast growth factor receptor binding	molecular_function	Binding to a type 2 fibroblast growth factor receptor (FGFR2).
GO:0005112	Notch binding	molecular_function	Binding to a Notch (N) protein, a surface receptor.
GO:0005113	patched binding	molecular_function	Binding to a patched (ptc) protein, a receptor for hedgehog proteins.
GO:0005114	type II transforming growth factor beta receptor binding	molecular_function	Binding to a type II transforming growth factor beta receptor.
GO:0005115	receptor tyrosine kinase-like orphan receptor binding	molecular_function	Binding to a receptor tyrosine kinase-like orphan receptor (Ror).
GO:0005117	wishful thinking binding	molecular_function	Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor.
GO:0005118	sevenless binding	molecular_function	Binding to a sevenless (sev) protein, a receptor tyrosine kinase.
GO:0005119	smoothened binding	molecular_function	Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.
GO:0005121	Toll binding	molecular_function	Binding to a Toll protein, a transmembrane receptor.
GO:0005122	torso binding	molecular_function	Binding to a torso (tor) protein, a receptor tyrosine kinase.
GO:0005123	death receptor binding	molecular_function	Binding to a member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
GO:0005124	scavenger receptor binding	molecular_function	Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.
GO:0005125	cytokine activity	molecular_function	The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.
GO:0005126	cytokine receptor binding	molecular_function	Binding to a cytokine receptor.
GO:0005127	ciliary neurotrophic factor receptor binding	molecular_function	Binding to a ciliary neurotrophic factor receptor.
GO:0005128	erythropoietin receptor binding	molecular_function	Binding to an erythropoietin receptor.
GO:0005129	granulocyte macrophage colony-stimulating factor receptor binding	molecular_function	Binding to a granulocyte macrophage colony-stimulating factor receptor.
GO:0005130	granulocyte colony-stimulating factor receptor binding	molecular_function	Binding to a granulocyte colony-stimulating factor receptor.
GO:0005131	growth hormone receptor binding	molecular_function	Binding to a growth hormone receptor.
GO:0005132	type I interferon receptor binding	molecular_function	Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
GO:0005133	type II interferon receptor binding	molecular_function	Binding to a type II interferon receptor. Type II interferon is also known as interferon-gamma.
GO:0005134	interleukin-2 receptor binding	molecular_function	Binding to an interleukin-2 receptor.
GO:0005135	interleukin-3 receptor binding	molecular_function	Binding to an interleukin-3 receptor.
GO:0005136	interleukin-4 receptor binding	molecular_function	Binding to an interleukin-4 receptor.
GO:0005137	interleukin-5 receptor binding	molecular_function	Binding to an interleukin-5 receptor.
GO:0005138	interleukin-6 receptor binding	molecular_function	Binding to an interleukin-6 receptor.
GO:0005139	interleukin-7 receptor binding	molecular_function	Binding to an interleukin-7 receptor.
GO:0005140	interleukin-9 receptor binding	molecular_function	Binding to an interleukin-9 receptor.
GO:0005141	interleukin-10 receptor binding	molecular_function	Binding to an interleukin-10 receptor.
GO:0005142	interleukin-11 receptor binding	molecular_function	Binding to an interleukin-11 receptor.
GO:0005143	interleukin-12 receptor binding	molecular_function	Binding to an interleukin-12 receptor.
GO:0005144	interleukin-13 receptor binding	molecular_function	Binding to an interleukin-13 receptor.
GO:0005146	leukemia inhibitory factor receptor binding	molecular_function	Binding to an leukemia inhibitory factor receptor.
GO:0005147	oncostatin-M receptor binding	molecular_function	Binding to an oncostatin-M receptor.
GO:0005148	prolactin receptor binding	molecular_function	Binding to a prolactin receptor.
GO:0005149	interleukin-1 receptor binding	molecular_function	Binding to an interleukin-1 receptor.
GO:0005150	interleukin-1, type I receptor binding	molecular_function	Binding to a Type I interleukin-1 receptor.
GO:0005151	interleukin-1, type II receptor binding	molecular_function	Binding to a Type II interleukin-1 receptor.
GO:0005152	interleukin-1 receptor antagonist activity	molecular_function	Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.
GO:0005153	interleukin-8 receptor binding	molecular_function	Binding to an interleukin-8 receptor.
GO:0005154	epidermal growth factor receptor binding	molecular_function	Binding to an epidermal growth factor receptor.
GO:0005157	macrophage colony-stimulating factor receptor binding	molecular_function	Binding to a macrophage colony-stimulating factor receptor.
GO:0005158	insulin receptor binding	molecular_function	Binding to an insulin receptor.
GO:0005159	insulin-like growth factor receptor binding	molecular_function	Binding to an insulin-like growth factor receptor.
GO:0005160	transforming growth factor beta receptor binding	molecular_function	Binding to a transforming growth factor beta receptor.
GO:0005161	platelet-derived growth factor receptor binding	molecular_function	Binding to a platelet-derived growth factor receptor.
GO:0005163	nerve growth factor receptor binding	molecular_function	Binding to a nerve growth factor receptor.
GO:0005164	tumor necrosis factor receptor binding	molecular_function	Binding to a tumor necrosis factor receptor.
GO:0005165	neurotrophin receptor binding	molecular_function	Binding to a neurotrophin receptor.
GO:0005166	neurotrophin p75 receptor binding	molecular_function	Binding to a neurotrophin p75 receptor.
GO:0005167	neurotrophin TRK receptor binding	molecular_function	Binding to a neurotrophin TRK receptor.
GO:0005168	neurotrophin TRKA receptor binding	molecular_function	Binding to a neurotrophin TRKA receptor.
GO:0005169	neurotrophin TRKB receptor binding	molecular_function	Binding to a neurotrophin TRKB receptor.
GO:0005170	neurotrophin TRKC receptor binding	molecular_function	Binding to a neurotrophin TRKC receptor.
GO:0005171	hepatocyte growth factor receptor binding	molecular_function	Binding to an hepatocyte growth factor receptor.
GO:0005172	vascular endothelial growth factor receptor binding	molecular_function	Binding to a vascular endothelial growth factor receptor.
GO:0005173	stem cell factor receptor binding	molecular_function	Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.
GO:0005174	CD40 receptor binding	molecular_function	Binding to CD40, a receptor found on the surface of all B-lymphocytes.
GO:0005175	CD27 receptor binding	molecular_function	Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells.
GO:0005176	ErbB-2 class receptor binding	molecular_function	Binding to a protein-tyrosine kinase receptor Neu/ErbB-2/HER2.
GO:0005178	integrin binding	molecular_function	Binding to an integrin.
GO:0005179	hormone activity	molecular_function	The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
GO:0005183	gonadotropin hormone-releasing hormone activity	molecular_function	The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.
GO:0005184	neuropeptide hormone activity	molecular_function	The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
GO:0005185	neurohypophyseal hormone activity	molecular_function	The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin.
GO:0005186	pheromone activity	molecular_function	The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.
GO:0005198	structural molecule activity	molecular_function	The action of a molecule that contributes to the structural integrity of a complex.
GO:0005199	structural constituent of cell wall	molecular_function	The action of a molecule that contributes to the structural integrity of a cell wall.
GO:0005200	structural constituent of cytoskeleton	molecular_function	The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
GO:0005201	extracellular matrix structural constituent	molecular_function	The action of a molecule that contributes to the structural integrity of the extracellular matrix.
GO:0005212	structural constituent of eye lens	molecular_function	The action of a molecule that contributes to the structural integrity of the lens of an eye.
GO:0005213	structural constituent of egg chorion	molecular_function	The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.
GO:0005214	structural constituent of chitin-based cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.
GO:0005215	transporter activity	molecular_function	Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0005216	monoatomic ion channel activity	molecular_function	Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0005217	intracellular ligand-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
GO:0005219	ryanodine-sensitive calcium-release channel activity	molecular_function	Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration and is sensitive to the plant alkaloid ryanodine.
GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.
GO:0005221	intracellular cyclic nucleotide activated monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
GO:0005222	intracellular cAMP-activated cation channel activity	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.
GO:0005223	intracellular cGMP-activated cation channel activity	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
GO:0005225	volume-sensitive anion channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic anion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
GO:0005227	calcium activated cation channel activity	molecular_function	Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
GO:0005228	intracellular sodium activated potassium channel activity	molecular_function	Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
GO:0005229	intracellular calcium activated chloride channel activity	molecular_function	Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.
GO:0005234	extracellularly glutamate-gated ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
GO:0005237	inhibitory extracellular ligand-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.
GO:0005242	inward rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
GO:0005243	gap junction channel activity	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.
GO:0005244	voltage-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0005245	voltage-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0005246	calcium channel regulator activity	molecular_function	Modulates the activity of a calcium channel.
GO:0005247	voltage-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0005248	voltage-gated sodium channel activity	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0005249	voltage-gated potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0005250	A-type (transient outward) potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.
GO:0005251	delayed rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
GO:0005252	open rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.
GO:0005253	monoatomic anion channel activity	molecular_function	Enables the energy-independent passage of a monoatomic anion across a lipid bilayer down a concentration gradient.
GO:0005254	chloride channel activity	molecular_function	Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0005260	intracellularly ATP-gated chloride channel activity	molecular_function	Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
GO:0005261	monoatomic cation channel activity	molecular_function	Enables the energy-independent passage of monoatomic cations across a lipid bilayer down a concentration gradient.
GO:0005262	calcium channel activity	molecular_function	Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0005267	potassium channel activity	molecular_function	Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0005272	sodium channel activity	molecular_function	Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0005274	allantoin:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.
GO:0005275	amine transmembrane transporter activity	molecular_function	Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
GO:0005277	acetylcholine transmembrane transporter activity	molecular_function	Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
GO:0005278	acetylcholine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out).
GO:0005280	amino acid:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).
GO:0005283	amino acid:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).
GO:0005287	high-affinity basic amino acid transmembrane transporter activity	molecular_function	Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005289	high-affinity L-arginine transmembrane transporter activity	molecular_function	Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005290	L-histidine transmembrane transporter activity	molecular_function	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0005291	high-affinity L-histidine transmembrane transporter activity	molecular_function	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005292	high-affinity lysine transmembrane transporter activity	molecular_function	Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity	molecular_function	Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0005295	neutral L-amino acid:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) = neutral L-amino acid(in) + Na+(in).
GO:0005297	proline:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).
GO:0005298	proline:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).
GO:0005300	high-affinity tryptophan transmembrane transporter activity	molecular_function	Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005302	L-tyrosine transmembrane transporter activity	molecular_function	Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid.
GO:0005304	L-valine transmembrane transporter activity	molecular_function	Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.
GO:0005307	choline:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in).
GO:0005308	creatine transmembrane transporter activity	molecular_function	Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
GO:0005309	creatine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).
GO:0005310	dicarboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
GO:0005313	L-glutamate transmembrane transporter activity	molecular_function	Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.
GO:0005314	high-affinity L-glutamate transmembrane transporter activity	molecular_function	Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005315	inorganic phosphate transmembrane transporter activity	molecular_function	Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0005316	high-affinity inorganic phosphate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005319	lipid transporter activity	molecular_function	Enables the directed movement of lipids into, out of or within a cell, or between cells.
GO:0005324	long-chain fatty acid transporter activity	molecular_function	Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0005326	neurotransmitter transmembrane transporter activity	molecular_function	Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
GO:0005328	neurotransmitter:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).
GO:0005330	dopamine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).
GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) + Cl-(out) = gamma-aminobutyric acid(in) + Na+(in) + Cl(in).
GO:0005334	norepinephrine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).
GO:0005335	serotonin:sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).
GO:0005337	nucleoside transmembrane transporter activity	molecular_function	Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.
GO:0005338	nucleotide-sugar transmembrane transporter activity	molecular_function	Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0005340	nucleotide-sulfate transmembrane transporter activity	molecular_function	Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.
GO:0005342	organic acid transmembrane transporter activity	molecular_function	Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.
GO:0005343	organic acid:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).
GO:0005344	oxygen carrier activity	molecular_function	Binding to oxygen and delivering it to an acceptor molecule or a specific location.
GO:0005345	purine nucleobase transmembrane transporter activity	molecular_function	Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
GO:0005346	purine ribonucleotide transmembrane transporter activity	molecular_function	Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.
GO:0005347	ATP transmembrane transporter activity	molecular_function	Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
GO:0005350	pyrimidine nucleobase transmembrane transporter activity	molecular_function	Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
GO:0005351	carbohydrate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in).
GO:0005352	alpha-glucoside:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.
GO:0005353	fructose transmembrane transporter activity	molecular_function	Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
GO:0005354	galactose transmembrane transporter activity	molecular_function	Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
GO:0005355	glucose transmembrane transporter activity	molecular_function	Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
GO:0005356	glucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
GO:0005358	high-affinity glucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0005359	low-affinity glucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
GO:0005360	insulin-responsive glucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
GO:0005362	low-affinity glucose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0005363	maltose transmembrane transporter activity	molecular_function	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.
GO:0005364	maltose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in).
GO:0005365	myo-inositol transmembrane transporter activity	molecular_function	Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.
GO:0005366	myo-inositol:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).
GO:0005367	myo-inositol:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in).
GO:0005368	taurine transmembrane transporter activity	molecular_function	Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.
GO:0005369	taurine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).
GO:0005371	tricarboxylate secondary active transmembrane transporter activity	molecular_function	Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0005372	water transmembrane transporter activity	molecular_function	Enables the transfer of water (H2O) from one side of a membrane to the other.
GO:0005375	copper ion transmembrane transporter activity	molecular_function	Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
GO:0005381	iron ion transmembrane transporter activity	molecular_function	Enables the transfer of iron (Fe) ions from one side of a membrane to the other.
GO:0005384	manganese ion transmembrane transporter activity	molecular_function	Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.
GO:0005385	zinc ion transmembrane transporter activity	molecular_function	Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
GO:0005388	P-type calcium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(in) = ADP + phosphate + Ca2+(out).
GO:0005391	P-type sodium:potassium-exchanging transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).
GO:0005402	carbohydrate:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).
GO:0005412	glucose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
GO:0005415	nucleoside:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).
GO:0005416	amino acid:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in).
GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity	molecular_function	Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.
GO:0005432	calcium:sodium antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).
GO:0005436	sodium:phosphate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).
GO:0005452	solute:inorganic anion antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion(out) + solute(in) = inorganic anion (in) + solute(out).
GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity	molecular_function	Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other.
GO:0005457	GDP-fucose transmembrane transporter activity	molecular_function	Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
GO:0005458	GDP-mannose transmembrane transporter activity	molecular_function	Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
GO:0005459	UDP-galactose transmembrane transporter activity	molecular_function	Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.
GO:0005460	UDP-glucose transmembrane transporter activity	molecular_function	Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.
GO:0005461	UDP-glucuronic acid transmembrane transporter activity	molecular_function	Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity	molecular_function	Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0005463	UDP-N-acetylgalactosamine transmembrane transporter activity	molecular_function	Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0005464	UDP-xylose transmembrane transporter activity	molecular_function	Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.
GO:0005469	succinate:fumarate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).
GO:0005471	ATP:ADP antiporter activity	molecular_function	Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).
GO:0005476	carnitine:acyl carnitine antiporter activity	molecular_function	Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial).
GO:0005477	pyruvate secondary active transmembrane transporter activity	molecular_function	Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0005483	soluble NSF attachment protein activity	molecular_function	Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.
GO:0005484	SNAP receptor activity	molecular_function	Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
GO:0005488	binding	molecular_function	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0005496	steroid binding	molecular_function	Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
GO:0005497	androgen binding	molecular_function	Binding to an androgen, a male sex hormone.
GO:0005499	vitamin D binding	molecular_function	Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0005500	juvenile hormone binding	molecular_function	Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
GO:0005501	retinoid binding	molecular_function	Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
GO:0005502	11-cis retinal binding	molecular_function	Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
GO:0005503	all-trans retinal binding	molecular_function	Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
GO:0005504	fatty acid binding	molecular_function	Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0005506	iron ion binding	molecular_function	Binding to an iron (Fe) ion.
GO:0005507	copper ion binding	molecular_function	Binding to a copper (Cu) ion.
GO:0005509	calcium ion binding	molecular_function	Binding to a calcium ion (Ca2+).
GO:0005513	detection of calcium ion	biological_process	The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.
GO:0005515	protein binding	molecular_function	Binding to a protein.
GO:0005516	calmodulin binding	molecular_function	Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
GO:0005518	collagen binding	molecular_function	Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
GO:0005519	cytoskeletal regulatory protein binding	molecular_function	Binding to a protein involved in modulating the reorganization of the cytoskeleton.
GO:0005520	insulin-like growth factor binding	molecular_function	Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
GO:0005521	lamin binding	molecular_function	Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
GO:0005522	profilin binding	molecular_function	Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
GO:0005523	tropomyosin binding	molecular_function	Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
GO:0005524	ATP binding	molecular_function	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0005525	GTP binding	molecular_function	Binding to GTP, guanosine triphosphate.
GO:0005527	macrolide binding	molecular_function	Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.
GO:0005528	FK506 binding	molecular_function	Binding to a 23-membered macrolide lactone FK506.
GO:0005534	galactose binding	molecular_function	Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
GO:0005536	glucose binding	molecular_function	Binding to D- or L-enantiomers of glucose.
GO:0005537	mannose binding	molecular_function	Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
GO:0005539	glycosaminoglycan binding	molecular_function	Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
GO:0005540	hyaluronic acid binding	molecular_function	Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
GO:0005542	folic acid binding	molecular_function	Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GO:0005543	phospholipid binding	molecular_function	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.
GO:0005544	calcium-dependent phospholipid binding	molecular_function	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
GO:0005545	1-phosphatidylinositol binding	molecular_function	Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	molecular_function	Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	molecular_function	Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
GO:0005548	phospholipid transporter activity	molecular_function	Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
GO:0005549	odorant binding	molecular_function	Binding to an odorant, any substance capable of stimulating the sense of smell.
GO:0005550	pheromone binding	molecular_function	Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
GO:0005575	cellular_component	cellular_component	A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
GO:0005576	extracellular region	cellular_component	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
GO:0005577	fibrinogen complex	cellular_component	A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
GO:0005579	membrane attack complex	cellular_component	A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
GO:0005581	collagen trimer	cellular_component	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.
GO:0005582	collagen type XV trimer	cellular_component	A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.
GO:0005583	fibrillar collagen trimer	cellular_component	Any triple helical collagen trimer that forms fibrils.
GO:0005584	collagen type I trimer	cellular_component	A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils.
GO:0005585	collagen type II trimer	cellular_component	A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.
GO:0005586	collagen type III trimer	cellular_component	A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
GO:0005587	collagen type IV trimer	cellular_component	A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.
GO:0005588	collagen type V trimer	cellular_component	A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.
GO:0005589	collagen type VI trimer	cellular_component	A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.
GO:0005590	collagen type VII trimer	cellular_component	A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.
GO:0005591	collagen type VIII trimer	cellular_component	A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.
GO:0005592	collagen type XI trimer	cellular_component	A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils.
GO:0005593	FACIT collagen trimer	cellular_component	A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.
GO:0005594	collagen type IX trimer	cellular_component	A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.
GO:0005595	collagen type XII trimer	cellular_component	A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
GO:0005596	collagen type XIV trimer	cellular_component	A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
GO:0005597	collagen type XVI trimer	cellular_component	A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.
GO:0005598	short-chain collagen trimer	cellular_component	Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.
GO:0005599	collagen type X trimer	cellular_component	A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).
GO:0005600	collagen type XIII trimer	cellular_component	A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.
GO:0005601	classical-complement-pathway C3/C5 convertase complex	cellular_component	A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.
GO:0005602	complement component C1 complex	cellular_component	A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.
GO:0005604	basement membrane	cellular_component	A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
GO:0005606	laminin-1 complex	cellular_component	A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
GO:0005607	laminin-2 complex	cellular_component	A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
GO:0005608	laminin-3 complex	cellular_component	A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
GO:0005609	laminin-4 complex	cellular_component	A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
GO:0005610	laminin-5 complex	cellular_component	A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.
GO:0005611	laminin-6 complex	cellular_component	A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
GO:0005612	laminin-7 complex	cellular_component	A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
GO:0005614	interstitial matrix	cellular_component	A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
GO:0005615	extracellular space	cellular_component	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
GO:0005616	larval serum protein complex	cellular_component	A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.
GO:0005618	cell wall	cellular_component	The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
GO:0005619	ascospore wall	cellular_component	The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
GO:0005621	cellular bud scar	cellular_component	Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
GO:0005622	intracellular anatomical structure	cellular_component	A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005628	prospore membrane	cellular_component	The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
GO:0005630	dityrosine layer of spore wall	cellular_component	The outermost layer of the spore wall, as described in Saccharomyces.
GO:0005631	chitosan layer of spore wall	cellular_component	The second outermost layer of the spore wall, as described in Saccharomyces.
GO:0005632	inner layer of spore wall	cellular_component	Either of the two innermost layers of the spore wall, as described in Saccharomyces.
GO:0005633	ascus lipid droplet	cellular_component	Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.
GO:0005634	nucleus	cellular_component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005635	nuclear envelope	cellular_component	The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
GO:0005637	nuclear inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
GO:0005638	lamin filament	cellular_component	Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.
GO:0005640	nuclear outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.
GO:0005641	nuclear envelope lumen	cellular_component	The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
GO:0005642	annulate lamellae	cellular_component	Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.
GO:0005643	nuclear pore	cellular_component	A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
GO:0005652	nuclear lamina	cellular_component	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
GO:0005654	nucleoplasm	cellular_component	That part of the nuclear content other than the chromosomes or the nucleolus.
GO:0005655	nucleolar ribonuclease P complex	cellular_component	A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
GO:0005656	nuclear pre-replicative complex	cellular_component	A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
GO:0005657	replication fork	cellular_component	The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
GO:0005658	alpha DNA polymerase:primase complex	cellular_component	A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.
GO:0005662	DNA replication factor A complex	cellular_component	A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.
GO:0005663	DNA replication factor C complex	cellular_component	A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.
GO:0005664	nuclear origin of replication recognition complex	cellular_component	A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.
GO:0005665	RNA polymerase II, core complex	cellular_component	RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
GO:0005666	RNA polymerase III complex	cellular_component	RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
GO:0005667	transcription regulator complex	cellular_component	A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
GO:0005668	RNA polymerase transcription factor SL1 complex	cellular_component	A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48.
GO:0005669	transcription factor TFIID complex	cellular_component	A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
GO:0005672	transcription factor TFIIA complex	cellular_component	A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).
GO:0005673	transcription factor TFIIE complex	cellular_component	A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.
GO:0005674	transcription factor TFIIF complex	cellular_component	A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.
GO:0005675	transcription factor TFIIH holo complex	cellular_component	A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.
GO:0005677	chromatin silencing complex	cellular_component	Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
GO:0005680	anaphase-promoting complex	cellular_component	A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
GO:0005681	spliceosomal complex	cellular_component	Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
GO:0005682	U5 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0005683	U7 snRNP	cellular_component	A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.
GO:0005684	U2-type spliceosomal complex	cellular_component	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
GO:0005685	U1 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0005686	U2 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0005687	U4 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.
GO:0005688	U6 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.
GO:0005689	U12-type spliceosomal complex	cellular_component	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.
GO:0005690	U4atac snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes.
GO:0005691	U6atac snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes.
GO:0005692	U11 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0005693	U12 snRNP	cellular_component	A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0005694	chromosome	cellular_component	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
GO:0005697	telomerase holoenzyme complex	cellular_component	Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.
GO:0005700	polytene chromosome	cellular_component	A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
GO:0005701	polytene chromosome chromocenter	cellular_component	A region at which the centric regions of polytene chromosomes are joined together.
GO:0005702	polytene chromosome weak point	cellular_component	A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.
GO:0005703	polytene chromosome puff	cellular_component	A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
GO:0005704	polytene chromosome band	cellular_component	A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.
GO:0005705	polytene chromosome interband	cellular_component	A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.
GO:0005706	polytene chromosome ectopic fiber	cellular_component	A thread-like connection joining two regions of ectopically paired polytene chromosomes.
GO:0005712	chiasma	cellular_component	A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.
GO:0005713	recombination nodule	cellular_component	An electron dense structure that is associated with meiotic chromosomes.
GO:0005714	early recombination nodule	cellular_component	An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.
GO:0005715	late recombination nodule	cellular_component	An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.
GO:0005721	pericentric heterochromatin	cellular_component	Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).
GO:0005722	beta-heterochromatin	cellular_component	A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.
GO:0005723	alpha-heterochromatin	cellular_component	A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.
GO:0005725	intercalary heterochromatin	cellular_component	Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.
GO:0005726	perichromatin fibrils	cellular_component	Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.
GO:0005727	extrachromosomal circular DNA	cellular_component	Circular DNA structures that are not part of a chromosome.
GO:0005728	extrachromosomal rDNA circle	cellular_component	Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.
GO:0005729	2-micrometer circle DNA	cellular_component	A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies.
GO:0005730	nucleolus	cellular_component	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
GO:0005731	nucleolus organizer region	cellular_component	A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.
GO:0005732	sno(s)RNA-containing ribonucleoprotein complex	cellular_component	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.
GO:0005736	RNA polymerase I complex	cellular_component	RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
GO:0005737	cytoplasm	cellular_component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005739	mitochondrion	cellular_component	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GO:0005740	mitochondrial envelope	cellular_component	The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
GO:0005741	mitochondrial outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
GO:0005742	mitochondrial outer membrane translocase complex	cellular_component	A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.
GO:0005743	mitochondrial inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	cellular_component	The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
GO:0005745	m-AAA complex	cellular_component	Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.
GO:0005746	mitochondrial respirasome	cellular_component	The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
GO:0005747	mitochondrial respiratory chain complex I	cellular_component	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	cellular_component	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
GO:0005750	mitochondrial respiratory chain complex III	cellular_component	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
GO:0005751	mitochondrial respiratory chain complex IV	cellular_component	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
GO:0005753	mitochondrial proton-transporting ATP synthase complex	cellular_component	A proton-transporting ATP synthase complex found in the mitochondrial membrane.
GO:0005754	mitochondrial proton-transporting ATP synthase, catalytic core	cellular_component	The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
GO:0005756	mitochondrial proton-transporting ATP synthase, central stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.
GO:0005757	mitochondrial permeability transition pore complex	cellular_component	A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).
GO:0005758	mitochondrial intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of the mitochondrial envelope.
GO:0005759	mitochondrial matrix	cellular_component	The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
GO:0005760	gamma DNA polymerase complex	cellular_component	A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.
GO:0005761	mitochondrial ribosome	cellular_component	A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
GO:0005762	mitochondrial large ribosomal subunit	cellular_component	The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
GO:0005763	mitochondrial small ribosomal subunit	cellular_component	The smaller of the two subunits of a mitochondrial ribosome.
GO:0005764	lysosome	cellular_component	A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
GO:0005765	lysosomal membrane	cellular_component	The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
GO:0005766	primary lysosome	cellular_component	A lysosome before it has fused with a vesicle or vacuole.
GO:0005767	secondary lysosome	cellular_component	Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.
GO:0005768	endosome	cellular_component	A vacuole to which materials ingested by endocytosis are delivered.
GO:0005769	early endosome	cellular_component	A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
GO:0005770	late endosome	cellular_component	A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
GO:0005771	multivesicular body	cellular_component	A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
GO:0005773	vacuole	cellular_component	A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
GO:0005774	vacuolar membrane	cellular_component	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
GO:0005775	vacuolar lumen	cellular_component	The volume enclosed within the vacuolar membrane.
GO:0005776	autophagosome	cellular_component	A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
GO:0005777	peroxisome	cellular_component	A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
GO:0005778	peroxisomal membrane	cellular_component	The lipid bilayer surrounding a peroxisome.
GO:0005780	extrinsic component of intraperoxisomal membrane	cellular_component	The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0005782	peroxisomal matrix	cellular_component	The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.
GO:0005783	endoplasmic reticulum	cellular_component	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
GO:0005784	Sec61 translocon complex	cellular_component	A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.
GO:0005785	signal recognition particle receptor complex	cellular_component	A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.
GO:0005786	signal recognition particle, endoplasmic reticulum targeting	cellular_component	A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.
GO:0005787	signal peptidase complex	cellular_component	A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
GO:0005788	endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the endoplasmic reticulum.
GO:0005789	endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the endoplasmic reticulum.
GO:0005790	smooth endoplasmic reticulum	cellular_component	The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
GO:0005791	rough endoplasmic reticulum	cellular_component	The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	cellular_component	A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.
GO:0005794	Golgi apparatus	cellular_component	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
GO:0005795	Golgi stack	cellular_component	The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
GO:0005796	Golgi lumen	cellular_component	The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
GO:0005797	Golgi medial cisterna	cellular_component	The middle Golgi cisterna (or cisternae).
GO:0005798	Golgi-associated vesicle	cellular_component	Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
GO:0005801	cis-Golgi network	cellular_component	The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
GO:0005802	trans-Golgi network	cellular_component	The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
GO:0005811	lipid droplet	cellular_component	An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
GO:0005813	centrosome	cellular_component	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
GO:0005814	centriole	cellular_component	A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
GO:0005815	microtubule organizing center	cellular_component	An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
GO:0005816	spindle pole body	cellular_component	The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
GO:0005818	aster	cellular_component	An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.
GO:0005819	spindle	cellular_component	The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
GO:0005821	intermediate layer of spindle pole body	cellular_component	Structure between the central and outer plaques of the spindle pole body.
GO:0005822	inner plaque of spindle pole body	cellular_component	One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.
GO:0005823	central plaque of spindle pole body	cellular_component	One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.
GO:0005824	outer plaque of spindle pole body	cellular_component	One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.
GO:0005825	half bridge of spindle pole body	cellular_component	Structure adjacent to the plaques of the spindle pole body.
GO:0005826	actomyosin contractile ring	cellular_component	A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
GO:0005827	polar microtubule	cellular_component	Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.
GO:0005828	kinetochore microtubule	cellular_component	Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.
GO:0005829	cytosol	cellular_component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0005831	steroid hormone aporeceptor complex	cellular_component	A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.
GO:0005832	chaperonin-containing T-complex	cellular_component	A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
GO:0005833	hemoglobin complex	cellular_component	An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.
GO:0005834	heterotrimeric G-protein complex	cellular_component	Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.
GO:0005835	fatty acid synthase complex	cellular_component	A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.
GO:0005836	fatty-acyl-CoA synthase complex	cellular_component	A protein complex that possesses fatty-acyl-CoA synthase activity.
GO:0005838	proteasome regulatory particle	cellular_component	A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.
GO:0005839	proteasome core complex	cellular_component	A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
GO:0005840	ribosome	cellular_component	An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
GO:0005844	polysome	cellular_component	A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
GO:0005845	mRNA cap binding complex	cellular_component	Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
GO:0005846	nuclear cap binding complex	cellular_component	A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	cellular_component	A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
GO:0005848	mRNA cleavage stimulating factor complex	cellular_component	A protein complex required for mRNA cleavage but not for poly(A) addition.
GO:0005849	mRNA cleavage factor complex	cellular_component	Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
GO:0005850	eukaryotic translation initiation factor 2 complex	cellular_component	Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
GO:0005851	eukaryotic translation initiation factor 2B complex	cellular_component	A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
GO:0005852	eukaryotic translation initiation factor 3 complex	cellular_component	A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
GO:0005853	eukaryotic translation elongation factor 1 complex	cellular_component	A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
GO:0005854	nascent polypeptide-associated complex	cellular_component	A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
GO:0005856	cytoskeleton	cellular_component	A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GO:0005858	axonemal dynein complex	cellular_component	A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
GO:0005859	muscle myosin complex	cellular_component	A filament of myosin found in a muscle cell of any type.
GO:0005861	troponin complex	cellular_component	A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.
GO:0005862	muscle thin filament tropomyosin	cellular_component	A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.
GO:0005863	striated muscle myosin thick filament	cellular_component	Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.
GO:0005865	striated muscle thin filament	cellular_component	Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
GO:0005868	cytoplasmic dynein complex	cellular_component	Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
GO:0005869	dynactin complex	cellular_component	A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.
GO:0005870	actin capping protein of dynactin complex	cellular_component	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.
GO:0005871	kinesin complex	cellular_component	Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
GO:0005872	minus-end kinesin complex	cellular_component	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.
GO:0005873	plus-end kinesin complex	cellular_component	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule.
GO:0005874	microtubule	cellular_component	Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
GO:0005875	microtubule associated complex	cellular_component	Any multimeric complex connected to a microtubule.
GO:0005876	spindle microtubule	cellular_component	Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
GO:0005879	axonemal microtubule	cellular_component	A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
GO:0005880	nuclear microtubule	cellular_component	Any microtubule in the nucleus of a cell.
GO:0005881	cytoplasmic microtubule	cellular_component	Any microtubule in the cytoplasm of a cell.
GO:0005882	intermediate filament	cellular_component	A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
GO:0005883	neurofilament	cellular_component	A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
GO:0005884	actin filament	cellular_component	A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
GO:0005885	Arp2/3 protein complex	cellular_component	A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
GO:0005886	plasma membrane	cellular_component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0005889	potassium:proton exchanging ATPase complex	cellular_component	A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
GO:0005890	sodium:potassium-exchanging ATPase complex	cellular_component	Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.
GO:0005891	voltage-gated calcium channel complex	cellular_component	A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
GO:0005892	acetylcholine-gated channel complex	cellular_component	A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
GO:0005893	interleukin-2 receptor complex	cellular_component	A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.
GO:0005894	interleukin-3 receptor complex	cellular_component	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5.
GO:0005895	interleukin-5 receptor complex	cellular_component	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3.
GO:0005896	interleukin-6 receptor complex	cellular_component	A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.
GO:0005897	interleukin-9 receptor complex	cellular_component	A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.
GO:0005898	interleukin-13 receptor complex	cellular_component	A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.
GO:0005899	insulin receptor complex	cellular_component	A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.
GO:0005900	oncostatin-M receptor complex	cellular_component	A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.
GO:0005901	caveola	cellular_component	A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
GO:0005902	microvillus	cellular_component	Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
GO:0005903	brush border	cellular_component	The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
GO:0005905	clathrin-coated pit	cellular_component	A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
GO:0005911	cell-cell junction	cellular_component	A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.
GO:0005912	adherens junction	cellular_component	A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
GO:0005914	spot adherens junction	cellular_component	A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.
GO:0005915	zonula adherens	cellular_component	A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
GO:0005916	fascia adherens	cellular_component	A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.
GO:0005917	nephrocyte diaphragm	cellular_component	A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.
GO:0005918	septate junction	cellular_component	A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.
GO:0005919	pleated septate junction	cellular_component	A septate junction in which regular arrays of electron-dense septae span the intermembrane space.
GO:0005920	smooth septate junction	cellular_component	A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.
GO:0005921	gap junction	cellular_component	A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.
GO:0005922	connexin complex	cellular_component	An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.
GO:0005923	bicellular tight junction	cellular_component	An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
GO:0005925	focal adhesion	cellular_component	A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).
GO:0005927	muscle tendon junction	cellular_component	A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
GO:0005929	cilium	cellular_component	A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
GO:0005930	axoneme	cellular_component	The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GO:0005931	axonemal nexin link	cellular_component	A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules.
GO:0005933	cellular bud	cellular_component	A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
GO:0005934	cellular bud tip	cellular_component	The end of a cellular bud distal to the site of attachment to the mother cell.
GO:0005935	cellular bud neck	cellular_component	The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
GO:0005937	mating projection	cellular_component	The projection formed by unicellular fungi in response to mating pheromone.
GO:0005938	cell cortex	cellular_component	The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
GO:0005940	septin ring	cellular_component	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.
GO:0005942	phosphatidylinositol 3-kinase complex	cellular_component	A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
GO:0005943	phosphatidylinositol 3-kinase complex, class IA	cellular_component	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
GO:0005944	phosphatidylinositol 3-kinase complex, class IB	cellular_component	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.
GO:0005945	6-phosphofructokinase complex	cellular_component	A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
GO:0005946	alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	cellular_component	A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.
GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex	cellular_component	Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
GO:0005948	acetolactate synthase complex	cellular_component	A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.
GO:0005950	anthranilate synthase complex	cellular_component	A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.
GO:0005951	carbamoyl-phosphate synthase complex	cellular_component	A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
GO:0005952	cAMP-dependent protein kinase complex	cellular_component	An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
GO:0005953	CAAX-protein geranylgeranyltransferase complex	cellular_component	A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.
GO:0005954	calcium- and calmodulin-dependent protein kinase complex	cellular_component	An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.
GO:0005955	calcineurin complex	cellular_component	A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
GO:0005956	protein kinase CK2 complex	cellular_component	A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.
GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex	cellular_component	A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.
GO:0005960	glycine cleavage complex	cellular_component	A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.
GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)	cellular_component	Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.
GO:0005963	magnesium-dependent protein serine/threonine phosphatase complex	cellular_component	An intracellular enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.
GO:0005964	phosphorylase kinase complex	cellular_component	An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a.
GO:0005965	protein farnesyltransferase complex	cellular_component	A protein complex that possesses protein farnesyltransferase activity.
GO:0005967	mitochondrial pyruvate dehydrogenase complex	cellular_component	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
GO:0005968	Rab-protein geranylgeranyltransferase complex	cellular_component	An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein).
GO:0005969	serine-pyruvate aminotransferase complex	cellular_component	An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.
GO:0005971	ribonucleoside-diphosphate reductase complex	cellular_component	An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
GO:0005975	carbohydrate metabolic process	biological_process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0005976	polysaccharide metabolic process	biological_process	The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0005977	glycogen metabolic process	biological_process	The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
GO:0005978	glycogen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
GO:0005979	regulation of glycogen biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
GO:0005980	glycogen catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
GO:0005981	regulation of glycogen catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
GO:0005982	starch metabolic process	biological_process	The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.
GO:0005983	starch catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.
GO:0005984	disaccharide metabolic process	biological_process	The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.
GO:0005985	sucrose metabolic process	biological_process	The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.
GO:0005986	sucrose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.
GO:0005987	sucrose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.
GO:0005988	lactose metabolic process	biological_process	The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.
GO:0005989	lactose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.
GO:0005990	lactose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.
GO:0005991	trehalose metabolic process	biological_process	The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
GO:0005992	trehalose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
GO:0005993	trehalose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
GO:0005994	melibiose metabolic process	biological_process	The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
GO:0005995	melibiose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
GO:0005996	monosaccharide metabolic process	biological_process	The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
GO:0005997	xylulose metabolic process	biological_process	The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
GO:0005998	xylulose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.
GO:0005999	xylulose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.
GO:0006000	fructose metabolic process	biological_process	The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
GO:0006001	fructose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.
GO:0006002	fructose 6-phosphate metabolic process	biological_process	The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
GO:0006003	fructose 2,6-bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
GO:0006004	fucose metabolic process	biological_process	The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.
GO:0006005	L-fucose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).
GO:0006006	glucose metabolic process	biological_process	The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
GO:0006007	glucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.
GO:0006009	glucose 1-phosphate phosphorylation	biological_process	The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate.
GO:0006011	UDP-glucose metabolic process	biological_process	The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
GO:0006012	galactose metabolic process	biological_process	The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
GO:0006013	mannose metabolic process	biological_process	The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
GO:0006014	D-ribose metabolic process	biological_process	The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
GO:0006016	2-deoxyribose 1-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
GO:0006017	deoxyribose 1,5-bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.
GO:0006018	2-deoxyribose 1-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
GO:0006019	deoxyribose 5-phosphate phosphorylation	biological_process	The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate.
GO:0006020	inositol metabolic process	biological_process	The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
GO:0006021	inositol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
GO:0006022	aminoglycan metabolic process	biological_process	The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
GO:0006023	aminoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
GO:0006024	glycosaminoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
GO:0006025	galactosaminoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.
GO:0006026	aminoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
GO:0006027	glycosaminoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
GO:0006028	galactosaminoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.
GO:0006029	proteoglycan metabolic process	biological_process	The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:0006030	chitin metabolic process	biological_process	The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006031	chitin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006032	chitin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006033	chitin localization	biological_process	A process in which chitin is transported to, or maintained in, a specific location.
GO:0006034	cuticle chitin metabolic process	biological_process	The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006035	cuticle chitin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006036	cuticle chitin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006037	cell wall chitin metabolic process	biological_process	The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006038	cell wall chitin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006039	cell wall chitin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006040	amino sugar metabolic process	biological_process	The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.
GO:0006041	glucosamine metabolic process	biological_process	The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
GO:0006042	glucosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
GO:0006043	glucosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
GO:0006044	N-acetylglucosamine metabolic process	biological_process	The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
GO:0006045	N-acetylglucosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
GO:0006046	N-acetylglucosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
GO:0006047	UDP-N-acetylglucosamine metabolic process	biological_process	The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0006049	UDP-N-acetylglucosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0006050	mannosamine metabolic process	biological_process	The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
GO:0006051	N-acetylmannosamine metabolic process	biological_process	The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
GO:0006052	N-acetylmannosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
GO:0006053	N-acetylmannosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
GO:0006054	N-acetylneuraminate metabolic process	biological_process	The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
GO:0006055	CMP-N-acetylneuraminate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.
GO:0006056	mannoprotein metabolic process	biological_process	The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues.
GO:0006057	mannoprotein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues.
GO:0006058	mannoprotein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.
GO:0006059	hexitol metabolic process	biological_process	The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule.
GO:0006060	sorbitol metabolic process	biological_process	The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
GO:0006061	sorbitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
GO:0006062	sorbitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
GO:0006063	uronic acid metabolic process	biological_process	The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.
GO:0006064	glucuronate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.
GO:0006065	UDP-glucuronate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
GO:0006066	alcohol metabolic process	biological_process	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
GO:0006067	ethanol metabolic process	biological_process	The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
GO:0006068	ethanol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
GO:0006069	ethanol oxidation	biological_process	An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
GO:0006070	octanol metabolic process	biological_process	The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.
GO:0006071	glycerol metabolic process	biological_process	The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
GO:0006072	glycerol-3-phosphate metabolic process	biological_process	The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
GO:0006074	(1->3)-beta-D-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
GO:0006075	(1->3)-beta-D-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
GO:0006076	(1->3)-beta-D-glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.
GO:0006077	(1->6)-beta-D-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.
GO:0006078	(1->6)-beta-D-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
GO:0006079	(1->6)-beta-D-glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.
GO:0006080	substituted mannan metabolic process	biological_process	The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.
GO:0006081	cellular aldehyde metabolic process	biological_process	The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
GO:0006082	organic acid metabolic process	biological_process	The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0006083	acetate metabolic process	biological_process	The chemical reactions and pathways involving acetate, the anion of acetic acid.
GO:0006084	acetyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
GO:0006085	acetyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
GO:0006089	lactate metabolic process	biological_process	The chemical reactions and pathways involving lactate, the anion of lactic acid.
GO:0006090	pyruvate metabolic process	biological_process	The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
GO:0006091	generation of precursor metabolites and energy	biological_process	The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
GO:0006094	gluconeogenesis	biological_process	The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
GO:0006096	glycolytic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
GO:0006097	glyoxylate cycle	biological_process	A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
GO:0006098	pentose-phosphate shunt	biological_process	The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).
GO:0006099	tricarboxylic acid cycle	biological_process	A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
GO:0006101	citrate metabolic process	biological_process	The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.
GO:0006102	isocitrate metabolic process	biological_process	The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.
GO:0006103	2-oxoglutarate metabolic process	biological_process	The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
GO:0006104	succinyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.
GO:0006105	succinate metabolic process	biological_process	The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
GO:0006106	fumarate metabolic process	biological_process	The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
GO:0006107	oxaloacetate metabolic process	biological_process	The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
GO:0006108	malate metabolic process	biological_process	The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
GO:0006109	regulation of carbohydrate metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
GO:0006110	regulation of glycolytic process	biological_process	Any process that modulates the frequency, rate or extent of glycolysis.
GO:0006111	regulation of gluconeogenesis	biological_process	Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
GO:0006112	energy reserve metabolic process	biological_process	The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.
GO:0006113	fermentation	biological_process	The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
GO:0006114	glycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
GO:0006115	ethanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
GO:0006116	NADH oxidation	biological_process	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD+.
GO:0006117	acetaldehyde metabolic process	biological_process	The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
GO:0006119	oxidative phosphorylation	biological_process	The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	biological_process	The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	biological_process	The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	biological_process	The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	biological_process	The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
GO:0006124	ferredoxin metabolic process	biological_process	The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.
GO:0006127	glycerophosphate shuttle	biological_process	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
GO:0006139	nucleobase-containing compound metabolic process	biological_process	Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0006140	regulation of nucleotide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GO:0006141	regulation of purine nucleobase metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.
GO:0006142	regulation of pyrimidine nucleobase metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
GO:0006144	purine nucleobase metabolic process	biological_process	The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
GO:0006145	purine nucleobase catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
GO:0006146	adenine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
GO:0006147	guanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
GO:0006148	inosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
GO:0006149	deoxyinosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.
GO:0006152	purine nucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0006154	adenosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
GO:0006157	deoxyadenosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
GO:0006161	deoxyguanosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
GO:0006163	purine nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006164	purine nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006166	purine ribonucleoside salvage	biological_process	Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
GO:0006167	AMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
GO:0006168	adenine salvage	biological_process	Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.
GO:0006169	adenosine salvage	biological_process	Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.
GO:0006170	dAMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
GO:0006171	cAMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
GO:0006172	ADP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
GO:0006173	dADP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
GO:0006175	dATP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
GO:0006176	dATP biosynthetic process from ADP	biological_process	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate.
GO:0006177	GMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
GO:0006178	guanine salvage	biological_process	Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.
GO:0006179	guanosine salvage	biological_process	Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.
GO:0006180	deoxyguanosine salvage	biological_process	Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis.
GO:0006181	dGMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
GO:0006182	cGMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.
GO:0006183	GTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.
GO:0006185	dGDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
GO:0006187	dGTP biosynthetic process from dGDP	biological_process	The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate.
GO:0006188	IMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.
GO:0006189	'de novo' IMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
GO:0006190	inosine salvage	biological_process	Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis.
GO:0006191	deoxyinosine salvage	biological_process	Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.
GO:0006193	ITP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.
GO:0006195	purine nucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006196	AMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.
GO:0006198	cAMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
GO:0006201	GMP catabolic process to IMP	biological_process	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate.
GO:0006202	GMP catabolic process to guanine	biological_process	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine.
GO:0006203	dGTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
GO:0006204	IMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.
GO:0006206	pyrimidine nucleobase metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
GO:0006208	pyrimidine nucleobase catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
GO:0006209	cytosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
GO:0006210	thymine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
GO:0006211	5-methylcytosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA.
GO:0006212	uracil catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
GO:0006213	pyrimidine nucleoside metabolic process	biological_process	The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0006214	thymidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
GO:0006216	cytidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.
GO:0006217	deoxycytidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
GO:0006218	uridine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
GO:0006219	deoxyuridine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
GO:0006220	pyrimidine nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006221	pyrimidine nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006222	UMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
GO:0006223	uracil salvage	biological_process	Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.
GO:0006225	UDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.
GO:0006226	dUMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).
GO:0006227	dUDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).
GO:0006228	UTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.
GO:0006229	dUTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.
GO:0006230	TMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.
GO:0006231	dTMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
GO:0006232	TDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.
GO:0006233	dTDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
GO:0006234	TTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate.
GO:0006235	dTTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
GO:0006236	cytidine salvage	biological_process	Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.
GO:0006237	deoxycytidine salvage	biological_process	Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis.
GO:0006238	CMP salvage	biological_process	Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.
GO:0006239	dCMP salvage	biological_process	Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis.
GO:0006240	dCDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.
GO:0006241	CTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.
GO:0006242	dCTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.
GO:0006244	pyrimidine nucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0006245	TDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.
GO:0006246	dTDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate.
GO:0006248	CMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate.
GO:0006249	dCMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.
GO:0006251	dCDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate.
GO:0006253	dCTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.
GO:0006254	CTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.
GO:0006256	UDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.
GO:0006257	dUDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.
GO:0006258	UDP-glucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
GO:0006259	DNA metabolic process	biological_process	Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0006260	DNA replication	biological_process	The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
GO:0006261	DNA-templated DNA replication	biological_process	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
GO:0006264	mitochondrial DNA replication	biological_process	The process in which new strands of DNA are synthesized in the mitochondrion.
GO:0006265	DNA topological change	biological_process	The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO:0006266	DNA ligation	biological_process	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication	biological_process	The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.
GO:0006268	DNA unwinding involved in DNA replication	biological_process	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
GO:0006269	DNA replication, synthesis of RNA primer	biological_process	The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.
GO:0006270	DNA replication initiation	biological_process	The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.
GO:0006271	DNA strand elongation involved in DNA replication	biological_process	The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication.
GO:0006272	leading strand elongation	biological_process	The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork.
GO:0006273	lagging strand elongation	biological_process	The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
GO:0006274	DNA replication termination	biological_process	The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.
GO:0006275	regulation of DNA replication	biological_process	Any process that modulates the frequency, rate or extent of DNA replication.
GO:0006276	plasmid maintenance	biological_process	The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.
GO:0006277	DNA amplification	biological_process	The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.
GO:0006278	RNA-templated DNA biosynthetic process	biological_process	A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.
GO:0006279	premeiotic DNA replication	biological_process	The replication of DNA that precedes meiotic cell division.
GO:0006281	DNA repair	biological_process	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:0006282	regulation of DNA repair	biological_process	Any process that modulates the frequency, rate or extent of DNA repair.
GO:0006283	transcription-coupled nucleotide-excision repair	biological_process	The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
GO:0006284	base-excision repair	biological_process	In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
GO:0006285	base-excision repair, AP site formation	biological_process	The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.
GO:0006287	base-excision repair, gap-filling	biological_process	Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.
GO:0006288	base-excision repair, DNA ligation	biological_process	The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair.
GO:0006289	nucleotide-excision repair	biological_process	A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
GO:0006290	pyrimidine dimer repair	biological_process	The repair of UV-induced T-T, C-T and C-C dimers.
GO:0006293	nucleotide-excision repair, preincision complex stabilization	biological_process	The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
GO:0006294	nucleotide-excision repair, preincision complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
GO:0006297	nucleotide-excision repair, DNA gap filling	biological_process	Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.
GO:0006298	mismatch repair	biological_process	A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
GO:0006301	postreplication repair	biological_process	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
GO:0006302	double-strand break repair	biological_process	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
GO:0006303	double-strand break repair via nonhomologous end joining	biological_process	The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
GO:0006304	DNA modification	biological_process	The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
GO:0006305	DNA alkylation	biological_process	The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.
GO:0006306	DNA methylation	biological_process	The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
GO:0006307	DNA dealkylation involved in DNA repair	biological_process	The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).
GO:0006308	DNA catabolic process	biological_process	The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
GO:0006309	apoptotic DNA fragmentation	biological_process	The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
GO:0006310	DNA recombination	biological_process	Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
GO:0006311	meiotic gene conversion	biological_process	The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.
GO:0006312	mitotic recombination	biological_process	The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.
GO:0006313	DNA transposition	biological_process	A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
GO:0006314	intron homing	biological_process	Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.
GO:0006315	homing of group II introns	biological_process	Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.
GO:0006316	movement of group I intron	biological_process	Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.
GO:0006325	chromatin organization	biological_process	The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
GO:0006334	nucleosome assembly	biological_process	The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
GO:0006335	DNA replication-dependent chromatin assembly	biological_process	The formation of nucleosomes on newly synthesized DNA, coupled to strand elongation.
GO:0006337	nucleosome disassembly	biological_process	The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
GO:0006338	chromatin remodeling	biological_process	A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
GO:0006346	DNA methylation-dependent heterochromatin formation	biological_process	Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
GO:0006349	regulation of gene expression by genomic imprinting	biological_process	An epigenetic mechanism of regulation of gene expression in which epigenetic modifications (imprints) are established during gametogenesis. For a given gene to show parentally biased expression, the imprint are established exclusively in one of the two parental genomes, thus generating an asymmetry between the maternal and paternal alleles.
GO:0006351	DNA-templated transcription	biological_process	The synthesis of an RNA transcript from a DNA template.
GO:0006352	DNA-templated transcription initiation	biological_process	The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.
GO:0006353	DNA-templated transcription termination	biological_process	The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
GO:0006354	DNA-templated transcription elongation	biological_process	The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
GO:0006355	regulation of DNA-templated transcription	biological_process	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006356	regulation of transcription by RNA polymerase I	biological_process	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I.
GO:0006357	regulation of transcription by RNA polymerase II	biological_process	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
GO:0006359	regulation of transcription by RNA polymerase III	biological_process	Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.
GO:0006360	transcription by RNA polymerase I	biological_process	The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
GO:0006361	transcription initiation at RNA polymerase I promoter	biological_process	A transcription initiation process that takes place at a RNA polymerase I gene promoter. Ribosomal RNAs (rRNA) genes are transcribed by RNA polymerase I.
GO:0006362	transcription elongation by RNA polymerase I	biological_process	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.
GO:0006363	termination of RNA polymerase I transcription	biological_process	A transcription termination process that completes the production of a ribosomal RNA transcript. RNAP I termination requires binding of a terminator protein to specific sequences downstream of the transcription unit.
GO:0006364	rRNA processing	biological_process	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
GO:0006366	transcription by RNA polymerase II	biological_process	The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
GO:0006367	transcription initiation at RNA polymerase II promoter	biological_process	A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II.
GO:0006368	transcription elongation by RNA polymerase II	biological_process	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
GO:0006369	termination of RNA polymerase II transcription	biological_process	A transcription termination process that completes the production of a primary RNA polymerase II transcript.
GO:0006370	7-methylguanosine mRNA capping	biological_process	Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
GO:0006376	mRNA splice site recognition	biological_process	Selection of a splice site by components of the assembling spliceosome.
GO:0006378	mRNA polyadenylation	biological_process	The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
GO:0006382	adenosine to inosine editing	biological_process	The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
GO:0006383	transcription by RNA polymerase III	biological_process	The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
GO:0006384	transcription initiation at RNA polymerase III promoter	biological_process	A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III.
GO:0006385	transcription elongation by RNA polymerase III	biological_process	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.
GO:0006386	termination of RNA polymerase III transcription	biological_process	A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues.
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	biological_process	Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
GO:0006390	mitochondrial transcription	biological_process	The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
GO:0006391	transcription initiation at mitochondrial promoter	biological_process	A transcription initiation process that takes place at a promoter on the mitochondrial chromosome.
GO:0006392	transcription elongation by mitochondrial RNA polymerase	biological_process	The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.
GO:0006393	termination of mitochondrial transcription	biological_process	A transcription termination process that completes the production of a primary mitochondrial transcript.
GO:0006396	RNA processing	biological_process	Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
GO:0006397	mRNA processing	biological_process	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage	biological_process	Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.
GO:0006399	tRNA metabolic process	biological_process	The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.
GO:0006400	tRNA modification	biological_process	The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
GO:0006401	RNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0006402	mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
GO:0006403	RNA localization	biological_process	A process in which RNA is transported to, or maintained in, a specific location.
GO:0006404	RNA import into nucleus	biological_process	The import of RNA from the cytoplasm to the nucleus.
GO:0006405	RNA export from nucleus	biological_process	The directed movement of RNA from the nucleus to the cytoplasm.
GO:0006406	mRNA export from nucleus	biological_process	The directed movement of mRNA from the nucleus to the cytoplasm.
GO:0006407	rRNA export from nucleus	biological_process	The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.
GO:0006408	snRNA export from nucleus	biological_process	The directed movement of snRNA from the nucleus to the cytoplasm.
GO:0006409	tRNA export from nucleus	biological_process	The directed movement of tRNA from the nucleus to the cytoplasm.
GO:0006412	translation	biological_process	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
GO:0006413	translational initiation	biological_process	The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GO:0006414	translational elongation	biological_process	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
GO:0006415	translational termination	biological_process	The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
GO:0006417	regulation of translation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0006418	tRNA aminoacylation for protein translation	biological_process	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
GO:0006419	alanyl-tRNA aminoacylation	biological_process	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.
GO:0006420	arginyl-tRNA aminoacylation	biological_process	The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006421	asparaginyl-tRNA aminoacylation	biological_process	The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.
GO:0006422	aspartyl-tRNA aminoacylation	biological_process	The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA.
GO:0006423	cysteinyl-tRNA aminoacylation	biological_process	The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006424	glutamyl-tRNA aminoacylation	biological_process	The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006425	glutaminyl-tRNA aminoacylation	biological_process	The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006426	glycyl-tRNA aminoacylation	biological_process	The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.
GO:0006427	histidyl-tRNA aminoacylation	biological_process	The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.
GO:0006428	isoleucyl-tRNA aminoacylation	biological_process	The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006429	leucyl-tRNA aminoacylation	biological_process	The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006430	lysyl-tRNA aminoacylation	biological_process	The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.
GO:0006431	methionyl-tRNA aminoacylation	biological_process	The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006432	phenylalanyl-tRNA aminoacylation	biological_process	The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006433	prolyl-tRNA aminoacylation	biological_process	The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA.
GO:0006434	seryl-tRNA aminoacylation	biological_process	The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.
GO:0006435	threonyl-tRNA aminoacylation	biological_process	The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.
GO:0006436	tryptophanyl-tRNA aminoacylation	biological_process	The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006437	tyrosyl-tRNA aminoacylation	biological_process	The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006438	valyl-tRNA aminoacylation	biological_process	The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
GO:0006446	regulation of translational initiation	biological_process	Any process that modulates the frequency, rate or extent of translational initiation.
GO:0006447	regulation of translational initiation by iron	biological_process	Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron.
GO:0006448	regulation of translational elongation	biological_process	Any process that modulates the frequency, rate, extent or accuracy of translational elongation.
GO:0006449	regulation of translational termination	biological_process	Any process that modulates the frequency, rate or extent of translational termination.
GO:0006450	regulation of translational fidelity	biological_process	Any process that modulates the ability of the translational apparatus to interpret the genetic code.
GO:0006451	translational readthrough	biological_process	The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.
GO:0006452	translational frameshifting	biological_process	A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.
GO:0006457	protein folding	biological_process	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
GO:0006458	'de novo' protein folding	biological_process	The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.
GO:0006463	steroid hormone receptor complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor.
GO:0006465	signal peptide processing	biological_process	The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
GO:0006468	protein phosphorylation	biological_process	The process of introducing a phosphate group on to a protein.
GO:0006469	negative regulation of protein kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
GO:0006470	protein dephosphorylation	biological_process	The process of removing one or more phosphoric residues from a protein.
GO:0006473	protein acetylation	biological_process	The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0006474	N-terminal protein amino acid acetylation	biological_process	The acetylation of the N-terminal amino acid of proteins.
GO:0006475	internal protein amino acid acetylation	biological_process	The addition of an acetyl group to a non-terminal amino acid in a protein.
GO:0006476	protein deacetylation	biological_process	The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0006477	protein sulfation	biological_process	The addition of a sulfate group as an ester to a protein amino acid.
GO:0006478	peptidyl-tyrosine sulfation	biological_process	The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.
GO:0006479	protein methylation	biological_process	The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
GO:0006480	N-terminal protein amino acid methylation	biological_process	The methylation of the N-terminal amino acid of a protein.
GO:0006481	C-terminal protein methylation	biological_process	The methylation of the C-terminal amino acid of a protein.
GO:0006482	protein demethylation	biological_process	The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
GO:0006486	protein glycosylation	biological_process	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GO:0006487	protein N-linked glycosylation	biological_process	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.
GO:0006489	dolichyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.
GO:0006491	N-glycan processing	biological_process	The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
GO:0006493	protein O-linked glycosylation	biological_process	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.
GO:0006497	protein lipidation	biological_process	The covalent attachment of lipid groups to an amino acid in a protein.
GO:0006498	N-terminal protein lipidation	biological_process	The covalent attachment of a lipid group to the amino terminus of a protein.
GO:0006499	N-terminal protein myristoylation	biological_process	The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
GO:0006500	N-terminal protein palmitoylation	biological_process	The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
GO:0006501	C-terminal protein lipidation	biological_process	The covalent attachment of a lipid group to the carboxy-terminus of a protein.
GO:0006505	GPI anchor metabolic process	biological_process	The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
GO:0006506	GPI anchor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
GO:0006507	GPI anchor release	biological_process	The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.
GO:0006508	proteolysis	biological_process	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0006509	membrane protein ectodomain proteolysis	biological_process	The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
GO:0006511	ubiquitin-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
GO:0006513	protein monoubiquitination	biological_process	Addition of a single ubiquitin group to a protein.
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	biological_process	The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
GO:0006516	glycoprotein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0006517	protein deglycosylation	biological_process	The removal of sugar residues from a glycosylated protein.
GO:0006518	peptide metabolic process	biological_process	The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
GO:0006520	amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups.
GO:0006521	regulation of cellular amino acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
GO:0006522	alanine metabolic process	biological_process	The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.
GO:0006523	alanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.
GO:0006524	alanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.
GO:0006525	arginine metabolic process	biological_process	The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
GO:0006526	arginine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
GO:0006527	arginine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
GO:0006528	asparagine metabolic process	biological_process	The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.
GO:0006529	asparagine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.
GO:0006530	asparagine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid.
GO:0006531	aspartate metabolic process	biological_process	The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
GO:0006532	aspartate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
GO:0006533	aspartate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
GO:0006534	cysteine metabolic process	biological_process	The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
GO:0006535	cysteine biosynthetic process from serine	biological_process	The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.
GO:0006536	glutamate metabolic process	biological_process	The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
GO:0006537	glutamate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.
GO:0006538	glutamate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.
GO:0006539	glutamate catabolic process via 2-oxoglutarate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.
GO:0006540	glutamate decarboxylation to succinate	biological_process	The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
GO:0006541	glutamine metabolic process	biological_process	The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
GO:0006542	glutamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.
GO:0006543	glutamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid.
GO:0006544	glycine metabolic process	biological_process	The chemical reactions and pathways involving glycine, aminoethanoic acid.
GO:0006545	glycine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
GO:0006546	glycine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
GO:0006547	histidine metabolic process	biological_process	The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0006548	histidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0006549	isoleucine metabolic process	biological_process	The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
GO:0006550	isoleucine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
GO:0006551	leucine metabolic process	biological_process	The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
GO:0006552	leucine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.
GO:0006553	lysine metabolic process	biological_process	The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.
GO:0006554	lysine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.
GO:0006555	methionine metabolic process	biological_process	The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
GO:0006556	S-adenosylmethionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
GO:0006558	L-phenylalanine metabolic process	biological_process	The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.
GO:0006559	L-phenylalanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
GO:0006560	proline metabolic process	biological_process	The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
GO:0006561	proline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
GO:0006562	proline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
GO:0006563	L-serine metabolic process	biological_process	The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
GO:0006564	L-serine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
GO:0006565	L-serine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
GO:0006566	threonine metabolic process	biological_process	The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
GO:0006567	threonine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
GO:0006568	tryptophan metabolic process	biological_process	The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0006569	tryptophan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0006570	tyrosine metabolic process	biological_process	The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
GO:0006571	tyrosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
GO:0006572	tyrosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
GO:0006573	valine metabolic process	biological_process	The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.
GO:0006574	valine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
GO:0006575	cellular modified amino acid metabolic process	biological_process	The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0006576	biogenic amine metabolic process	biological_process	The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
GO:0006577	amino-acid betaine metabolic process	biological_process	The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.
GO:0006578	amino-acid betaine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.
GO:0006579	amino-acid betaine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.
GO:0006580	ethanolamine metabolic process	biological_process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
GO:0006581	acetylcholine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.
GO:0006582	melanin metabolic process	biological_process	The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
GO:0006583	melanin biosynthetic process from tyrosine	biological_process	The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.
GO:0006584	catecholamine metabolic process	biological_process	The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
GO:0006585	dopamine biosynthetic process from tyrosine	biological_process	The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.
GO:0006586	indolalkylamine metabolic process	biological_process	The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
GO:0006587	serotonin biosynthetic process from tryptophan	biological_process	The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
GO:0006589	octopamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
GO:0006590	thyroid hormone generation	biological_process	The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
GO:0006591	ornithine metabolic process	biological_process	The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
GO:0006592	ornithine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
GO:0006593	ornithine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
GO:0006595	polyamine metabolic process	biological_process	The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
GO:0006596	polyamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
GO:0006597	spermine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
GO:0006598	polyamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.
GO:0006599	phosphagen metabolic process	biological_process	The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
GO:0006600	creatine metabolic process	biological_process	The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
GO:0006601	creatine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.
GO:0006602	creatinine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.
GO:0006603	phosphocreatine metabolic process	biological_process	The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.
GO:0006604	phosphoarginine metabolic process	biological_process	The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates.
GO:0006605	protein targeting	biological_process	The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0006606	protein import into nucleus	biological_process	The directed movement of a protein from the cytoplasm to the nucleus.
GO:0006607	NLS-bearing protein import into nucleus	biological_process	The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope.
GO:0006610	ribosomal protein import into nucleus	biological_process	The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus.
GO:0006611	protein export from nucleus	biological_process	The directed movement of a protein from the nucleus into the cytoplasm.
GO:0006612	protein targeting to membrane	biological_process	The process of directing proteins towards a membrane, usually using signals contained within the protein.
GO:0006613	cotranslational protein targeting to membrane	biological_process	The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	biological_process	The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
GO:0006615	SRP-dependent cotranslational protein targeting to membrane, docking	biological_process	The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	biological_process	The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	biological_process	The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.
GO:0006618	SRP-dependent cotranslational protein targeting to membrane, signal sequence processing	biological_process	The removal of the signal peptide from a nascent protein during cotranslational membrane targeting.
GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	biological_process	The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
GO:0006621	protein retention in ER lumen	biological_process	The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
GO:0006622	protein targeting to lysosome	biological_process	The process of directing proteins towards the lysosome using signals contained within the protein.
GO:0006623	protein targeting to vacuole	biological_process	The process of directing proteins towards the vacuole, usually using signals contained within the protein.
GO:0006624	vacuolar protein processing	biological_process	Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.
GO:0006625	protein targeting to peroxisome	biological_process	The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
GO:0006626	protein targeting to mitochondrion	biological_process	The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
GO:0006627	protein processing involved in protein targeting to mitochondrion	biological_process	The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
GO:0006629	lipid metabolic process	biological_process	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0006631	fatty acid metabolic process	biological_process	The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0006633	fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
GO:0006634	hexadecanal biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.
GO:0006635	fatty acid beta-oxidation	biological_process	A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0006636	unsaturated fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
GO:0006637	acyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
GO:0006638	neutral lipid metabolic process	biological_process	The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.
GO:0006639	acylglycerol metabolic process	biological_process	The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
GO:0006640	monoacylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
GO:0006641	triglyceride metabolic process	biological_process	The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
GO:0006642	triglyceride mobilization	biological_process	The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.
GO:0006643	membrane lipid metabolic process	biological_process	The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
GO:0006644	phospholipid metabolic process	biological_process	The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0006646	phosphatidylethanolamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
GO:0006647	phosphatidyl-N-monomethylethanolamine biosynthetic process	biological_process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.
GO:0006648	dihydrosphingosine-1-P pathway	biological_process	A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.
GO:0006649	phospholipid transfer to membrane	biological_process	The transfer of a phospholipid from its site of synthesis to the plasma membrane.
GO:0006650	glycerophospholipid metabolic process	biological_process	The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
GO:0006651	diacylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
GO:0006653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	biological_process	The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.
GO:0006654	phosphatidic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
GO:0006655	phosphatidylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.
GO:0006656	phosphatidylcholine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0006657	CDP-choline pathway	biological_process	The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.
GO:0006658	phosphatidylserine metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.
GO:0006659	phosphatidylserine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
GO:0006660	phosphatidylserine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
GO:0006661	phosphatidylinositol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0006662	glycerol ether metabolic process	biological_process	The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
GO:0006663	platelet activating factor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
GO:0006664	glycolipid metabolic process	biological_process	The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.
GO:0006665	sphingolipid metabolic process	biological_process	The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0006666	3-keto-sphinganine metabolic process	biological_process	The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
GO:0006667	sphinganine metabolic process	biological_process	The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.
GO:0006668	sphinganine-1-phosphate metabolic process	biological_process	The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
GO:0006669	sphinganine-1-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
GO:0006670	sphingosine metabolic process	biological_process	The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
GO:0006671	phytosphingosine metabolic process	biological_process	The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.
GO:0006672	ceramide metabolic process	biological_process	The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
GO:0006673	inositol phosphoceramide metabolic process	biological_process	The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.
GO:0006675	mannosyl-inositol phosphorylceramide metabolic process	biological_process	The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
GO:0006676	mannosyl diphosphorylinositol ceramide metabolic process	biological_process	The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.
GO:0006677	glycosylceramide metabolic process	biological_process	The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
GO:0006678	glucosylceramide metabolic process	biological_process	The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
GO:0006679	glucosylceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
GO:0006680	glucosylceramide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
GO:0006681	galactosylceramide metabolic process	biological_process	The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
GO:0006682	galactosylceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
GO:0006683	galactosylceramide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
GO:0006684	sphingomyelin metabolic process	biological_process	The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
GO:0006685	sphingomyelin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
GO:0006686	sphingomyelin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
GO:0006687	glycosphingolipid metabolic process	biological_process	The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
GO:0006688	glycosphingolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
GO:0006689	ganglioside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
GO:0006690	icosanoid metabolic process	biological_process	The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
GO:0006691	leukotriene metabolic process	biological_process	The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
GO:0006692	prostanoid metabolic process	biological_process	The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.
GO:0006693	prostaglandin metabolic process	biological_process	The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
GO:0006694	steroid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
GO:0006695	cholesterol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0006696	ergosterol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
GO:0006697	ecdysone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
GO:0006699	bile acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
GO:0006700	C21-steroid hormone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
GO:0006701	progesterone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
GO:0006702	androgen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
GO:0006703	estrogen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
GO:0006704	glucocorticoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
GO:0006705	mineralocorticoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
GO:0006706	steroid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:0006707	cholesterol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0006708	ecdysone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
GO:0006709	progesterone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
GO:0006710	androgen catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
GO:0006711	estrogen catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
GO:0006712	mineralocorticoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
GO:0006713	glucocorticoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
GO:0006714	sesquiterpenoid metabolic process	biological_process	The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.
GO:0006715	farnesol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
GO:0006716	juvenile hormone metabolic process	biological_process	The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
GO:0006718	juvenile hormone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
GO:0006719	juvenile hormone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
GO:0006720	isoprenoid metabolic process	biological_process	The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0006721	terpenoid metabolic process	biological_process	The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
GO:0006722	triterpenoid metabolic process	biological_process	The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units.
GO:0006723	cuticle hydrocarbon biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
GO:0006725	cellular aromatic compound metabolic process	biological_process	The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0006726	eye pigment biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
GO:0006727	ommochrome biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
GO:0006728	pteridine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
GO:0006729	tetrahydrobiopterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
GO:0006730	one-carbon metabolic process	biological_process	The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
GO:0006734	NADH metabolic process	biological_process	The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
GO:0006735	NADH regeneration	biological_process	A metabolic process that generates a pool of NADH by the reduction of NAD+.
GO:0006738	nicotinamide riboside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
GO:0006739	NADP metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
GO:0006740	NADPH regeneration	biological_process	A metabolic process that generates a pool of NADPH by the reduction of NADP+.
GO:0006741	NADP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.
GO:0006742	NADP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
GO:0006743	ubiquinone metabolic process	biological_process	The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.
GO:0006744	ubiquinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
GO:0006746	FADH2 metabolic process	biological_process	The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide.
GO:0006747	FAD biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.
GO:0006748	lipoamide metabolic process	biological_process	The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.
GO:0006749	glutathione metabolic process	biological_process	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
GO:0006750	glutathione biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
GO:0006751	glutathione catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
GO:0006753	nucleoside phosphate metabolic process	biological_process	The chemical reactions and pathways involving any phosphorylated nucleoside.
GO:0006754	ATP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0006756	AMP phosphorylation	biological_process	The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.
GO:0006760	folic acid-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
GO:0006761	dihydrofolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate.
GO:0006766	vitamin metabolic process	biological_process	The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
GO:0006767	water-soluble vitamin metabolic process	biological_process	The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.
GO:0006768	biotin metabolic process	biological_process	The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
GO:0006769	nicotinamide metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.
GO:0006771	riboflavin metabolic process	biological_process	The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
GO:0006772	thiamine metabolic process	biological_process	The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0006775	fat-soluble vitamin metabolic process	biological_process	The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
GO:0006776	vitamin A metabolic process	biological_process	The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
GO:0006778	porphyrin-containing compound metabolic process	biological_process	The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
GO:0006779	porphyrin-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
GO:0006780	uroporphyrinogen III biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.
GO:0006781	succinyl-CoA pathway	biological_process	The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.
GO:0006782	protoporphyrinogen IX biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
GO:0006783	heme biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
GO:0006784	heme A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3.
GO:0006785	heme B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
GO:0006786	heme C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.
GO:0006787	porphyrin-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
GO:0006788	heme oxidation	biological_process	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.
GO:0006789	bilirubin conjugation	biological_process	The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.
GO:0006790	sulfur compound metabolic process	biological_process	The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0006791	sulfur utilization	biological_process	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism.
GO:0006792	regulation of sulfur utilization	biological_process	Any process that modulates the frequency, rate or extent of sulfur utilization.
GO:0006793	phosphorus metabolic process	biological_process	The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0006794	phosphorus utilization	biological_process	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism.
GO:0006795	regulation of phosphorus utilization	biological_process	Any process that modulates the frequency, rate or extent of phosphorus utilization.
GO:0006796	phosphate-containing compound metabolic process	biological_process	The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0006797	polyphosphate metabolic process	biological_process	The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.
GO:0006798	polyphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid.
GO:0006799	polyphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.
GO:0006801	superoxide metabolic process	biological_process	The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
GO:0006805	xenobiotic metabolic process	biological_process	The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0006807	nitrogen compound metabolic process	biological_process	The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
GO:0006808	regulation of nitrogen utilization	biological_process	Any process that modulates the frequency, rate or extent of nitrogen utilization.
GO:0006809	nitric oxide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
GO:0006810	transport	biological_process	The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0006811	monoatomic ion transport	biological_process	The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0006812	monoatomic cation transport	biological_process	The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.
GO:0006813	potassium ion transport	biological_process	The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006814	sodium ion transport	biological_process	The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006816	calcium ion transport	biological_process	The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006817	phosphate ion transport	biological_process	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006820	monoatomic anion transport	biological_process	The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom.
GO:0006821	chloride transport	biological_process	The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006824	cobalt ion transport	biological_process	The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006825	copper ion transport	biological_process	The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006826	iron ion transport	biological_process	The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006828	manganese ion transport	biological_process	The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006829	zinc ion transport	biological_process	The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006833	water transport	biological_process	The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006835	dicarboxylic acid transport	biological_process	The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006836	neurotransmitter transport	biological_process	The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
GO:0006837	serotonin transport	biological_process	The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
GO:0006839	mitochondrial transport	biological_process	Transport of substances into, out of or within a mitochondrion.
GO:0006842	tricarboxylic acid transport	biological_process	The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006843	mitochondrial citrate transmembrane transport	biological_process	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.
GO:0006844	acyl carnitine transport	biological_process	The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.
GO:0006846	acetate transport	biological_process	The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006847	plasma membrane acetate transport	biological_process	The directed movement of acetate across a plasma membrane.
GO:0006848	pyruvate transport	biological_process	The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006849	plasma membrane pyruvate transport	biological_process	The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane.
GO:0006850	mitochondrial pyruvate transmembrane transport	biological_process	The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0006851	mitochondrial calcium ion transmembrane transport	biological_process	The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0006853	carnitine shuttle	biological_process	The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.
GO:0006855	xenobiotic transmembrane transport	biological_process	The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0006856	eye pigment precursor transport	biological_process	The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006857	oligopeptide transport	biological_process	The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0006858	extracellular transport	biological_process	The transport of substances that occurs outside cells.
GO:0006860	extracellular amino acid transport	biological_process	The directed extracellular movement of amino acids.
GO:0006862	nucleotide transport	biological_process	The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.
GO:0006863	purine nucleobase transport	biological_process	The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006864	pyrimidine nucleotide transport	biological_process	The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.
GO:0006865	amino acid transport	biological_process	The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006867	asparagine transport	biological_process	The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006868	glutamine transport	biological_process	The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006869	lipid transport	biological_process	The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0006873	intracellular monoatomic ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0006874	intracellular calcium ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell.
GO:0006877	intracellular cobalt ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of cobalt ions within a cell.
GO:0006878	intracellular copper ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.
GO:0006879	intracellular iron ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell.
GO:0006880	intracellular sequestering of iron ion	biological_process	The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.
GO:0006881	extracellular sequestering of iron ion	biological_process	The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system.
GO:0006882	intracellular zinc ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of zinc ions within a cell.
GO:0006883	intracellular sodium ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell.
GO:0006884	cell volume homeostasis	biological_process	Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
GO:0006885	regulation of pH	biological_process	Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
GO:0006886	intracellular protein transport	biological_process	The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0006887	exocytosis	biological_process	A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	biological_process	The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	biological_process	The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
GO:0006891	intra-Golgi vesicle-mediated transport	biological_process	The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
GO:0006892	post-Golgi vesicle-mediated transport	biological_process	The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
GO:0006893	Golgi to plasma membrane transport	biological_process	The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
GO:0006895	Golgi to endosome transport	biological_process	The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
GO:0006896	Golgi to vacuole transport	biological_process	The directed movement of substances from the Golgi to the vacuole.
GO:0006897	endocytosis	biological_process	A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.
GO:0006898	receptor-mediated endocytosis	biological_process	An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
GO:0006900	vesicle budding from membrane	biological_process	The evagination of a membrane, resulting in formation of a vesicle.
GO:0006901	vesicle coating	biological_process	A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.
GO:0006903	vesicle targeting	biological_process	The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
GO:0006904	vesicle docking involved in exocytosis	biological_process	The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
GO:0006906	vesicle fusion	biological_process	Fusion of the membrane of a transport vesicle with its target membrane.
GO:0006907	pinocytosis	biological_process	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
GO:0006909	phagocytosis	biological_process	A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
GO:0006910	phagocytosis, recognition	biological_process	The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
GO:0006911	phagocytosis, engulfment	biological_process	The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
GO:0006913	nucleocytoplasmic transport	biological_process	The directed movement of molecules between the nucleus and the cytoplasm.
GO:0006914	autophagy	biological_process	The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GO:0006915	apoptotic process	biological_process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	biological_process	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	biological_process	The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.
GO:0006924	activation-induced cell death of T cells	biological_process	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.
GO:0006925	inflammatory cell apoptotic process	biological_process	Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.
GO:0006929	substrate-dependent cell migration	biological_process	The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
GO:0006930	substrate-dependent cell migration, cell extension	biological_process	The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	biological_process	The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.
GO:0006932	substrate-dependent cell migration, cell contraction	biological_process	The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	biological_process	The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.
GO:0006934	substrate-bound cell migration, adhesion receptor recycling	biological_process	The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.
GO:0006935	chemotaxis	biological_process	The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0006936	muscle contraction	biological_process	A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
GO:0006937	regulation of muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of muscle contraction.
GO:0006939	smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
GO:0006940	regulation of smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle contraction.
GO:0006941	striated muscle contraction	biological_process	A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
GO:0006942	regulation of striated muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of striated muscle contraction.
GO:0006948	induction by virus of host cell-cell fusion	biological_process	The process of syncytia-forming cell-cell fusion, caused by a virus.
GO:0006949	syncytium formation	biological_process	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.
GO:0006950	response to stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0006952	defense response	biological_process	Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0006953	acute-phase response	biological_process	An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.
GO:0006954	inflammatory response	biological_process	The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
GO:0006955	immune response	biological_process	Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0006956	complement activation	biological_process	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
GO:0006957	complement activation, alternative pathway	biological_process	Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
GO:0006958	complement activation, classical pathway	biological_process	Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
GO:0006959	humoral immune response	biological_process	An immune response mediated through a body fluid.
GO:0006962	male-specific antibacterial humoral response	biological_process	An immune response against bacteria, specific to males and mediated through a body fluid.
GO:0006963	positive regulation of antibacterial peptide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	biological_process	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	biological_process	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
GO:0006967	positive regulation of antifungal peptide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.
GO:0006968	cellular defense response	biological_process	A defense response that is mediated by cells.
GO:0006970	response to osmotic stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0006971	hypotonic response	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
GO:0006972	hyperosmotic response	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
GO:0006973	intracellular accumulation of glycerol	biological_process	The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.
GO:0006974	DNA damage response	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	biological_process	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	biological_process	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
GO:0006979	response to oxidative stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0006982	response to lipid hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.
GO:0006983	ER overload response	biological_process	The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.
GO:0006984	ER-nucleus signaling pathway	biological_process	The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.
GO:0006986	response to unfolded protein	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	biological_process	The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.
GO:0006991	response to sterol depletion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0006995	cellular response to nitrogen starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
GO:0006996	organelle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0006997	nucleus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GO:0006998	nuclear envelope organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
GO:0006999	nuclear pore organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore.
GO:0007000	nucleolus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.
GO:0007004	telomere maintenance via telomerase	biological_process	The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
GO:0007005	mitochondrion organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
GO:0007006	mitochondrial membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
GO:0007007	inner mitochondrial membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.
GO:0007008	outer mitochondrial membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.
GO:0007009	plasma membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
GO:0007010	cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0007014	actin ubiquitination	biological_process	The modification of actin by addition of ubiquitin groups.
GO:0007015	actin filament organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
GO:0007017	microtubule-based process	biological_process	Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GO:0007018	microtubule-based movement	biological_process	A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GO:0007019	microtubule depolymerization	biological_process	The removal of tubulin heterodimers from one or both ends of a microtubule.
GO:0007020	microtubule nucleation	biological_process	The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
GO:0007021	tubulin complex assembly	biological_process	The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.
GO:0007023	post-chaperonin tubulin folding pathway	biological_process	Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.
GO:0007026	negative regulation of microtubule depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
GO:0007027	negative regulation of axonemal microtubule depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.
GO:0007028	cytoplasm organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0007029	endoplasmic reticulum organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
GO:0007030	Golgi organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
GO:0007031	peroxisome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GO:0007032	endosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
GO:0007033	vacuole organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0007034	vacuolar transport	biological_process	The directed movement of substances into, out of or within a vacuole.
GO:0007035	vacuolar acidification	biological_process	Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
GO:0007036	vacuolar calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.
GO:0007038	endocytosed protein transport to vacuole	biological_process	The directed movement of proteins imported into a cell by endocytosis to the vacuole.
GO:0007039	protein catabolic process in the vacuole	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
GO:0007040	lysosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
GO:0007041	lysosomal transport	biological_process	The directed movement of substances into, out of or within a lysosome.
GO:0007042	lysosomal lumen acidification	biological_process	Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
GO:0007043	cell-cell junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
GO:0007044	cell-substrate junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
GO:0007049	cell cycle	biological_process	The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0007051	spindle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
GO:0007052	mitotic spindle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
GO:0007053	spindle assembly involved in male meiosis	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
GO:0007054	spindle assembly involved in male meiosis I	biological_process	The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
GO:0007055	spindle assembly involved in male meiosis II	biological_process	The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
GO:0007056	spindle assembly involved in female meiosis	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
GO:0007057	spindle assembly involved in female meiosis I	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
GO:0007058	spindle assembly involved in female meiosis II	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
GO:0007059	chromosome segregation	biological_process	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
GO:0007060	male meiosis chromosome segregation	biological_process	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
GO:0007062	sister chromatid cohesion	biological_process	The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
GO:0007063	regulation of sister chromatid cohesion	biological_process	Any process that modulates the frequency, rate or extent of sister chromatid cohesion.
GO:0007064	mitotic sister chromatid cohesion	biological_process	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
GO:0007065	male meiosis sister chromatid cohesion	biological_process	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.
GO:0007066	female meiosis sister chromatid cohesion	biological_process	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.
GO:0007072	positive regulation of transcription involved in exit from mitosis	biological_process	Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
GO:0007073	positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
GO:0007074	positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
GO:0007075	positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
GO:0007076	mitotic chromosome condensation	biological_process	The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
GO:0007077	mitotic nuclear membrane disassembly	biological_process	The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.
GO:0007078	lamin depolymerization	biological_process	The cell cycle process in which lamin is depolymerized.
GO:0007079	mitotic chromosome movement towards spindle pole	biological_process	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
GO:0007080	mitotic metaphase chromosome alignment	biological_process	A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
GO:0007084	mitotic nuclear membrane reassembly	biological_process	The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.
GO:0007086	vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly	biological_process	The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.
GO:0007087	mitotic nuclear pore complex reassembly	biological_process	The cell cycle process in which nuclear pore complexes reform during mitotic cell division.
GO:0007088	regulation of mitotic nuclear division	biological_process	Any process that modulates the frequency, rate or extent of mitosis.
GO:0007089	traversing start control point of mitotic cell cycle	biological_process	A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	biological_process	The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
GO:0007093	mitotic cell cycle checkpoint signaling	biological_process	A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
GO:0007094	mitotic spindle assembly checkpoint signaling	biological_process	A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC).
GO:0007095	mitotic G2 DNA damage checkpoint signaling	biological_process	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
GO:0007096	regulation of exit from mitosis	biological_process	Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
GO:0007097	nuclear migration	biological_process	The directed movement of the nucleus to a specific location within a cell.
GO:0007098	centrosome cycle	biological_process	The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
GO:0007099	centriole replication	biological_process	The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
GO:0007100	mitotic centrosome separation	biological_process	Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
GO:0007105	cytokinesis, division site positioning	biological_process	The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions.
GO:0007107	membrane addition at site of cytokinesis	biological_process	Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
GO:0007110	meiosis I cytokinesis	biological_process	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
GO:0007111	meiosis II cytokinesis	biological_process	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
GO:0007112	male meiosis cytokinesis	biological_process	A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.
GO:0007113	endomitotic cell cycle	biological_process	A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
GO:0007114	cell budding	biological_process	A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
GO:0007116	regulation of cell budding	biological_process	Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.
GO:0007117	budding cell bud growth	biological_process	The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
GO:0007118	budding cell apical bud growth	biological_process	Growth at the tip of a bud, in a cell that reproduces by budding.
GO:0007119	budding cell isotropic bud growth	biological_process	Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.
GO:0007120	axial cellular bud site selection	biological_process	The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.
GO:0007121	bipolar cellular bud site selection	biological_process	The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
GO:0007124	pseudohyphal growth	biological_process	The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.
GO:0007127	meiosis I	biological_process	The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
GO:0007128	meiotic prophase I	biological_process	The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GO:0007129	homologous chromosome pairing at meiosis	biological_process	The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
GO:0007130	synaptonemal complex assembly	biological_process	The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
GO:0007131	reciprocal meiotic recombination	biological_process	The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
GO:0007132	meiotic metaphase I	biological_process	The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.
GO:0007133	meiotic anaphase I	biological_process	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.
GO:0007134	meiotic telophase I	biological_process	The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GO:0007135	meiosis II	biological_process	The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
GO:0007136	meiotic prophase II	biological_process	The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GO:0007137	meiotic metaphase II	biological_process	The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.
GO:0007138	meiotic anaphase II	biological_process	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.
GO:0007139	meiotic telophase II	biological_process	The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GO:0007140	male meiotic nuclear division	biological_process	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
GO:0007141	male meiosis I	biological_process	A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
GO:0007142	male meiosis II	biological_process	A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.
GO:0007143	female meiotic nuclear division	biological_process	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
GO:0007144	female meiosis I	biological_process	The cell cycle process in which the first meiotic division occurs in the female germline.
GO:0007146	meiotic recombination nodule assembly	biological_process	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.
GO:0007147	female meiosis II	biological_process	The cell cycle process in which the second meiotic division occurs in the female germline.
GO:0007154	cell communication	biological_process	Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0007155	cell adhesion	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	biological_process	The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	biological_process	The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
GO:0007158	neuron cell-cell adhesion	biological_process	The attachment of a neuron to another cell via adhesion molecules.
GO:0007159	leukocyte cell-cell adhesion	biological_process	The attachment of a leukocyte to another cell via adhesion molecules.
GO:0007160	cell-matrix adhesion	biological_process	The binding of a cell to the extracellular matrix via adhesion molecules.
GO:0007161	calcium-independent cell-matrix adhesion	biological_process	The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.
GO:0007162	negative regulation of cell adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
GO:0007163	establishment or maintenance of cell polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
GO:0007164	establishment of tissue polarity	biological_process	Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
GO:0007165	signal transduction	biological_process	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0007166	cell surface receptor signaling pathway	biological_process	The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0007167	enzyme-linked receptor protein signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007168	receptor guanylyl cyclase signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	biological_process	Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.
GO:0007172	signal complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.
GO:0007173	epidermal growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0007174	epidermal growth factor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
GO:0007176	regulation of epidermal growth factor-activated receptor activity	biological_process	Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007179	transforming growth factor beta receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007181	transforming growth factor beta receptor complex assembly	biological_process	The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007186	G protein-coupled receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP).
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity and a subsequent increase in the intracellular concentration of cyclic AMP (cAMP).
GO:0007190	activation of adenylate cyclase activity	biological_process	Any process that initiates the activity of the inactive enzyme adenylate cyclase.
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	biological_process	An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007192	adenylate cyclase-activating serotonin receptor signaling pathway	biological_process	An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP).
GO:0007194	negative regulation of adenylate cyclase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007196	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007197	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0007199	G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger	biological_process	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
GO:0007202	activation of phospholipase C activity	biological_process	The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.
GO:0007204	positive regulation of cytosolic calcium ion concentration	biological_process	Any process that increases the concentration of calcium ions in the cytosol.
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
GO:0007206	phospholipase C-activating G protein-coupled glutamate receptor signaling pathway	biological_process	A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007207	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	biological_process	A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007208	phospholipase C-activating serotonin receptor signaling pathway	biological_process	A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007209	phospholipase C-activating tachykinin receptor signaling pathway	biological_process	A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007210	serotonin receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
GO:0007211	octopamine or tyramine signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by octopamine or tyramine binding to their receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription, and ending with the regulation of a downstream cellular process. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters.
GO:0007212	dopamine receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.
GO:0007214	gamma-aminobutyric acid signaling pathway	biological_process	The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.
GO:0007215	glutamate receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007216	G protein-coupled glutamate receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0007217	tachykinin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. Tachykinin is a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2).
GO:0007218	neuropeptide signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0007219	Notch signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007220	Notch receptor processing	biological_process	The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
GO:0007221	positive regulation of transcription of Notch receptor target	biological_process	The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.
GO:0007223	Wnt signaling pathway, calcium modulating pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
GO:0007224	smoothened signaling pathway	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
GO:0007225	patched ligand maturation	biological_process	The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
GO:0007227	signal transduction downstream of smoothened	biological_process	The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.
GO:0007228	positive regulation of hh target transcription factor activity	biological_process	Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
GO:0007229	integrin-mediated signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0007231	osmosensory signaling pathway	biological_process	The series of molecular signals initiated in response to osmotic change.
GO:0007232	osmosensory signaling pathway via Sho1 osmosensor	biological_process	The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
GO:0007234	osmosensory signaling via phosphorelay pathway	biological_process	The series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
GO:0007249	canonical NF-kappaB signal transduction	biological_process	The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB, also known as the canonical NF-kappaB signaling cascade. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. The canonical NF-kappaB pathway is  mainly stimulated by proinflammatory cytokines such as IL-1beta, tumor necrosis factor (TNF)-alpha, antigen ligands, and toll-like receptors (TLRs).
GO:0007250	activation of NF-kappaB-inducing kinase activity	biological_process	The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
GO:0007252	I-kappaB phosphorylation	biological_process	The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
GO:0007253	cytoplasmic sequestering of NF-kappaB	biological_process	The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
GO:0007254	JNK cascade	biological_process	An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
GO:0007258	JUN phosphorylation	biological_process	The process of introducing a phosphate group into a JUN protein.
GO:0007259	receptor signaling pathway via JAK-STAT	biological_process	Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
GO:0007260	tyrosine phosphorylation of STAT protein	biological_process	The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0007263	nitric oxide mediated signal transduction	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.
GO:0007264	small GTPase mediated signal transduction	biological_process	The series of molecular signals in which a small monomeric GTPase relays a signal.
GO:0007265	Ras protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
GO:0007266	Rho protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
GO:0007267	cell-cell signaling	biological_process	Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
GO:0007268	chemical synaptic transmission	biological_process	The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0007269	neurotransmitter secretion	biological_process	The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
GO:0007270	neuron-neuron synaptic transmission	biological_process	The process of synaptic transmission from a neuron to another neuron across a synapse.
GO:0007271	synaptic transmission, cholinergic	biological_process	The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0007272	ensheathment of neurons	biological_process	The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
GO:0007274	neuromuscular synaptic transmission	biological_process	The process of synaptic transmission from a neuron to a muscle, across a synapse.
GO:0007275	multicellular organism development	biological_process	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0007276	gamete generation	biological_process	The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
GO:0007277	pole cell development	biological_process	The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure.
GO:0007278	pole cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007279	pole cell formation	biological_process	Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.
GO:0007280	pole cell migration	biological_process	The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form.
GO:0007281	germ cell development	biological_process	The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
GO:0007282	cystoblast division	biological_process	Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.
GO:0007283	spermatogenesis	biological_process	The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
GO:0007284	spermatogonial cell division	biological_process	The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).
GO:0007285	primary spermatocyte growth	biological_process	The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.
GO:0007286	spermatid development	biological_process	The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
GO:0007287	Nebenkern assembly	biological_process	Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.
GO:0007288	sperm axoneme assembly	biological_process	The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.
GO:0007289	spermatid nucleus differentiation	biological_process	The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.
GO:0007290	spermatid nucleus elongation	biological_process	The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.
GO:0007291	sperm individualization	biological_process	The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.
GO:0007292	female gamete generation	biological_process	Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
GO:0007293	germarium-derived egg chamber formation	biological_process	Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.
GO:0007294	germarium-derived oocyte fate determination	biological_process	The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.
GO:0007295	growth of a germarium-derived egg chamber	biological_process	Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.
GO:0007296	vitellogenesis	biological_process	The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.
GO:0007297	follicle cell of egg chamber migration	biological_process	The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.
GO:0007298	border follicle cell migration	biological_process	The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
GO:0007299	follicle cell of egg chamber-cell adhesion	biological_process	The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.
GO:0007300	ovarian nurse cell to oocyte transport	biological_process	Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.
GO:0007301	female germline ring canal formation	biological_process	Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.
GO:0007302	nurse cell nucleus anchoring	biological_process	Attachment of the nurse cell nucleus to the plasma membrane.
GO:0007303	cytoplasmic transport, nurse cell to oocyte	biological_process	The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.
GO:0007304	chorion-containing eggshell formation	biological_process	The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.
GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation	biological_process	Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.
GO:0007306	egg chorion assembly	biological_process	Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.
GO:0007307	eggshell chorion gene amplification	biological_process	Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.
GO:0007308	oocyte construction	biological_process	The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.
GO:0007309	oocyte axis specification	biological_process	The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.
GO:0007310	oocyte dorsal/ventral axis specification	biological_process	The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.
GO:0007311	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded	biological_process	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.
GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification	biological_process	The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.
GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded	biological_process	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.
GO:0007314	oocyte anterior/posterior axis specification	biological_process	Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.
GO:0007315	pole plasm assembly	biological_process	Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.
GO:0007316	pole plasm RNA localization	biological_process	Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0007317	regulation of pole plasm oskar mRNA localization	biological_process	Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
GO:0007318	pole plasm protein localization	biological_process	Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0007319	negative regulation of oskar mRNA translation	biological_process	Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.
GO:0007320	insemination	biological_process	The introduction of semen or sperm into the genital tract of a female.
GO:0007321	sperm displacement	biological_process	The physical displacement of sperm stored from previous mating encounters.
GO:0007323	peptide pheromone maturation	biological_process	The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.
GO:0007338	single fertilization	biological_process	The union of male and female gametes to form a zygote.
GO:0007339	binding of sperm to zona pellucida	biological_process	The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
GO:0007340	acrosome reaction	biological_process	The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
GO:0007341	penetration of zona pellucida	biological_process	The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	biological_process	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
GO:0007343	egg activation	biological_process	The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.
GO:0007344	pronuclear fusion	biological_process	The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.
GO:0007346	regulation of mitotic cell cycle	biological_process	Any process that modulates the rate or extent of progress through the mitotic cell cycle.
GO:0007347	regulation of preblastoderm mitotic cell cycle	biological_process	A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.
GO:0007348	regulation of syncytial blastoderm mitotic cell cycle	biological_process	A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle.
GO:0007349	cellularization	biological_process	The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.
GO:0007350	blastoderm segmentation	biological_process	The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
GO:0007351	tripartite regional subdivision	biological_process	Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.
GO:0007352	zygotic specification of dorsal/ventral axis	biological_process	The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.
GO:0007354	zygotic determination of anterior/posterior axis, embryo	biological_process	The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.
GO:0007355	anterior region determination	biological_process	Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.
GO:0007356	thorax and anterior abdomen determination	biological_process	Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.
GO:0007359	posterior abdomen determination	biological_process	The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.
GO:0007362	terminal region determination	biological_process	Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.
GO:0007365	periodic partitioning	biological_process	The regionalization process that divides the spatial regions of an embryo into serially repeated regions.
GO:0007366	periodic partitioning by pair rule gene	biological_process	Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.
GO:0007367	segment polarity determination	biological_process	Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.
GO:0007368	determination of left/right symmetry	biological_process	The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
GO:0007369	gastrulation	biological_process	A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
GO:0007370	ventral furrow formation	biological_process	Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
GO:0007371	ventral midline determination	biological_process	The regionalization process in which the area where the ventral midline will form is specified.
GO:0007374	posterior midgut invagination	biological_process	Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior.
GO:0007375	anterior midgut invagination	biological_process	Internalization of the anterior midgut into the interior of the embryo.
GO:0007376	cephalic furrow formation	biological_process	Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.
GO:0007377	germ-band extension	biological_process	Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.
GO:0007378	amnioserosa formation	biological_process	Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.
GO:0007379	segment specification	biological_process	The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.
GO:0007380	specification of segmental identity, head	biological_process	The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007381	specification of segmental identity, labial segment	biological_process	The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007382	specification of segmental identity, maxillary segment	biological_process	The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007383	specification of segmental identity, antennal segment	biological_process	The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007384	specification of segmental identity, thorax	biological_process	The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007385	specification of segmental identity, abdomen	biological_process	The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0007386	compartment pattern specification	biological_process	The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.
GO:0007387	anterior compartment pattern formation	biological_process	The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.
GO:0007388	posterior compartment specification	biological_process	The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.
GO:0007389	pattern specification process	biological_process	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
GO:0007390	germ-band shortening	biological_process	The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
GO:0007391	dorsal closure	biological_process	The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
GO:0007392	initiation of dorsal closure	biological_process	Events that occur at the start of dorsal closure.
GO:0007393	dorsal closure, leading edge cell fate determination	biological_process	The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007394	dorsal closure, elongation of leading edge cells	biological_process	The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis.
GO:0007395	dorsal closure, spreading of leading edge cells	biological_process	Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.
GO:0007396	suture of dorsal opening	biological_process	Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole.
GO:0007398	ectoderm development	biological_process	The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.
GO:0007399	nervous system development	biological_process	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
GO:0007400	neuroblast fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
GO:0007402	ganglion mother cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007403	glial cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007405	neuroblast proliferation	biological_process	The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
GO:0007406	negative regulation of neuroblast proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
GO:0007407	neuroblast activation	biological_process	A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0007409	axonogenesis	biological_process	De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
GO:0007411	axon guidance	biological_process	The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
GO:0007412	axon target recognition	biological_process	The process in which an axon recognizes and binds to a set of cells with which it may form stable connections.
GO:0007413	axonal fasciculation	biological_process	The collection of axons into a bundle of rods, known as a fascicle.
GO:0007414	axonal defasciculation	biological_process	Separation of axons away from a bundle of axons known as a fascicle.
GO:0007415	defasciculation of motor neuron axon	biological_process	Separation of a motor axon away from a bundle of axons known as a fascicle.
GO:0007416	synapse assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
GO:0007417	central nervous system development	biological_process	The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GO:0007418	ventral midline development	biological_process	The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.
GO:0007419	ventral cord development	biological_process	The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
GO:0007420	brain development	biological_process	The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
GO:0007421	stomatogastric nervous system development	biological_process	The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.
GO:0007422	peripheral nervous system development	biological_process	The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
GO:0007423	sensory organ development	biological_process	The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
GO:0007424	open tracheal system development	biological_process	The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
GO:0007425	epithelial cell fate determination, open tracheal system	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.
GO:0007426	tracheal outgrowth, open tracheal system	biological_process	The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.
GO:0007427	epithelial cell migration, open tracheal system	biological_process	The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
GO:0007428	primary branching, open tracheal system	biological_process	Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.
GO:0007429	secondary branching, open tracheal system	biological_process	Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster.
GO:0007430	terminal branching, open tracheal system	biological_process	Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
GO:0007431	salivary gland development	biological_process	The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.
GO:0007432	salivary gland boundary specification	biological_process	Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
GO:0007433	larval salivary gland boundary specification	biological_process	Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
GO:0007434	adult salivary gland boundary specification	biological_process	Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
GO:0007435	salivary gland morphogenesis	biological_process	The process in which the anatomical structures of the salivary gland are generated and organized.
GO:0007436	larval salivary gland morphogenesis	biological_process	The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.
GO:0007437	adult salivary gland morphogenesis	biological_process	The process in which the anatomical structures of the adult salivary gland are generated and organized.
GO:0007438	oenocyte development	biological_process	The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
GO:0007439	ectodermal digestive tract development	biological_process	The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.
GO:0007440	foregut morphogenesis	biological_process	The process in which the anatomical structures of the foregut are generated and organized.
GO:0007441	anterior midgut (ectodermal) morphogenesis	biological_process	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.
GO:0007442	hindgut morphogenesis	biological_process	The process in which the anatomical structures of the hindgut are generated and organized.
GO:0007443	Malpighian tubule morphogenesis	biological_process	The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
GO:0007444	imaginal disc development	biological_process	The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).
GO:0007445	determination of imaginal disc primordium	biological_process	Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment.
GO:0007446	imaginal disc growth	biological_process	The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
GO:0007447	imaginal disc pattern formation	biological_process	The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
GO:0007448	anterior/posterior pattern specification, imaginal disc	biological_process	The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.
GO:0007449	proximal/distal pattern formation, imaginal disc	biological_process	The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
GO:0007450	dorsal/ventral pattern formation, imaginal disc	biological_process	The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
GO:0007451	dorsal/ventral lineage restriction, imaginal disc	biological_process	Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.
GO:0007453	clypeo-labral disc morphogenesis	biological_process	The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus.
GO:0007454	labial disc morphogenesis	biological_process	The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.
GO:0007455	eye-antennal disc morphogenesis	biological_process	The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.
GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis	biological_process	The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.
GO:0007460	R8 cell fate commitment	biological_process	The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.
GO:0007462	R1/R6 cell fate commitment	biological_process	The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres.
GO:0007463	R2/R5 cell fate commitment	biological_process	The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres.
GO:0007464	R3/R4 cell fate commitment	biological_process	The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
GO:0007465	R7 cell fate commitment	biological_process	The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.
GO:0007469	antennal development	biological_process	The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.
GO:0007470	prothoracic disc morphogenesis	biological_process	The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.
GO:0007472	wing disc morphogenesis	biological_process	The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.
GO:0007473	wing disc proximal/distal pattern formation	biological_process	The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.
GO:0007474	imaginal disc-derived wing vein specification	biological_process	The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces	biological_process	The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
GO:0007476	imaginal disc-derived wing morphogenesis	biological_process	The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
GO:0007477	notum development	biological_process	The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.
GO:0007478	leg disc morphogenesis	biological_process	The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.
GO:0007479	leg disc proximal/distal pattern formation	biological_process	The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.
GO:0007480	imaginal disc-derived leg morphogenesis	biological_process	The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
GO:0007481	haltere disc morphogenesis	biological_process	The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.
GO:0007482	haltere development	biological_process	The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.
GO:0007483	genital disc morphogenesis	biological_process	The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.
GO:0007484	imaginal disc-derived genitalia development	biological_process	The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
GO:0007485	imaginal disc-derived male genitalia development	biological_process	The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
GO:0007486	imaginal disc-derived female genitalia development	biological_process	The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
GO:0007487	analia development	biological_process	The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.
GO:0007488	histoblast morphogenesis	biological_process	The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.
GO:0007489	maintenance of imaginal histoblast diploidy	biological_process	The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells.
GO:0007490	tergite morphogenesis	biological_process	The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.
GO:0007491	sternite morphogenesis	biological_process	The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.
GO:0007492	endoderm development	biological_process	The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.
GO:0007493	endodermal cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007494	midgut development	biological_process	The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	biological_process	The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.
GO:0007496	anterior midgut development	biological_process	The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.
GO:0007497	posterior midgut development	biological_process	The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.
GO:0007498	mesoderm development	biological_process	The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
GO:0007499	ectoderm and mesoderm interaction	biological_process	A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.
GO:0007500	mesodermal cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007501	mesodermal cell fate specification	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0007502	digestive tract mesoderm development	biological_process	The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.
GO:0007503	fat body development	biological_process	The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.
GO:0007504	larval fat body development	biological_process	The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.
GO:0007505	adult fat body development	biological_process	The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.
GO:0007506	gonadal mesoderm development	biological_process	The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.
GO:0007507	heart development	biological_process	The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
GO:0007508	larval heart development	biological_process	The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.
GO:0007509	mesoderm migration involved in gastrulation	biological_process	The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.
GO:0007510	cardioblast cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0007512	adult heart development	biological_process	The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.
GO:0007516	hemocyte development	biological_process	The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
GO:0007517	muscle organ development	biological_process	The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
GO:0007518	myoblast fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0007519	skeletal muscle tissue development	biological_process	The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
GO:0007520	myoblast fusion	biological_process	A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0007521	muscle cell fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0007522	visceral muscle development	biological_process	The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.
GO:0007523	larval visceral muscle development	biological_process	The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure.
GO:0007524	adult visceral muscle development	biological_process	The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.
GO:0007525	somatic muscle development	biological_process	The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
GO:0007526	larval somatic muscle development	biological_process	The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
GO:0007527	adult somatic muscle development	biological_process	The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.
GO:0007528	neuromuscular junction development	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
GO:0007529	establishment of synaptic specificity at neuromuscular junction	biological_process	The biological process in which a synapse between a motor neuron and a muscle is initially formed.
GO:0007530	sex determination	biological_process	Any process that establishes and transmits the specification of sexual status of an individual organism.
GO:0007531	mating type determination	biological_process	Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.
GO:0007532	regulation of mating-type specific transcription, DNA-templated	biological_process	Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0007533	mating type switching	biological_process	The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.
GO:0007534	gene conversion at mating-type locus	biological_process	The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.
GO:0007535	donor selection	biological_process	The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
GO:0007536	activation of recombination (HML)	biological_process	The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.
GO:0007537	inactivation of recombination (HML)	biological_process	The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.
GO:0007538	primary sex determination	biological_process	The sex determination process that results in the initial specification of sexual status of an individual organism.
GO:0007539	primary sex determination, soma	biological_process	The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.
GO:0007540	sex determination, establishment of X:A ratio	biological_process	The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it.
GO:0007541	sex determination, primary response to X:A ratio	biological_process	The developmental process in which an organism interprets its X to autosomal chromosomal complement.
GO:0007542	primary sex determination, germ-line	biological_process	The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.
GO:0007543	sex determination, somatic-gonadal interaction	biological_process	The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.
GO:0007545	processes downstream of sex determination signal	biological_process	The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways.
GO:0007546	somatic processes downstream of sex determination signal	biological_process	The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways.
GO:0007547	germ-line processes downstream of sex determination signal	biological_process	The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways.
GO:0007548	sex differentiation	biological_process	The establishment of the sex of an organism by physical differentiation.
GO:0007549	dosage compensation	biological_process	Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.
GO:0007552	metamorphosis	biological_process	A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
GO:0007553	regulation of ecdysteroid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.
GO:0007554	regulation of ecdysteroid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
GO:0007555	regulation of ecdysteroid secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell.
GO:0007556	regulation of juvenile hormone metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
GO:0007557	regulation of juvenile hormone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
GO:0007558	regulation of juvenile hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of juvenile hormone secretion.
GO:0007560	imaginal disc morphogenesis	biological_process	The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
GO:0007561	imaginal disc eversion	biological_process	The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.
GO:0007562	eclosion	biological_process	The emergence of an adult insect from a pupa case.
GO:0007563	regulation of eclosion	biological_process	Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.
GO:0007564	regulation of chitin-based cuticle tanning	biological_process	Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.
GO:0007565	female pregnancy	biological_process	The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
GO:0007566	embryo implantation	biological_process	Attachment of the blastocyst to the uterine lining.
GO:0007567	parturition	biological_process	The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.
GO:0007584	response to nutrient	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
GO:0007585	respiratory gaseous exchange by respiratory system	biological_process	The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.
GO:0007586	digestion	biological_process	The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0007588	excretion	biological_process	The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
GO:0007589	body fluid secretion	biological_process	The controlled release of a fluid by a cell or tissue in an animal.
GO:0007591	molting cycle, chitin-based cuticle	biological_process	The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.
GO:0007593	chitin-based cuticle sclerotization	biological_process	The process of hardening of a chitin-based cuticle.
GO:0007594	puparial adhesion	biological_process	The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation.
GO:0007595	lactation	biological_process	The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
GO:0007596	blood coagulation	biological_process	The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
GO:0007597	blood coagulation, intrinsic pathway	biological_process	A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
GO:0007598	blood coagulation, extrinsic pathway	biological_process	A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.
GO:0007599	hemostasis	biological_process	The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
GO:0007600	sensory perception	biological_process	The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0007601	visual perception	biological_process	The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
GO:0007602	phototransduction	biological_process	The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
GO:0007603	phototransduction, visible light	biological_process	The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
GO:0007604	phototransduction, UV	biological_process	The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.
GO:0007605	sensory perception of sound	biological_process	The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
GO:0007606	sensory perception of chemical stimulus	biological_process	The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0007608	sensory perception of smell	biological_process	The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
GO:0007610	behavior	biological_process	The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.
GO:0007611	learning or memory	biological_process	The acquisition and processing of information and/or the storage and retrieval of this information over time.
GO:0007612	learning	biological_process	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
GO:0007613	memory	biological_process	The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
GO:0007614	short-term memory	biological_process	The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
GO:0007615	anesthesia-resistant memory	biological_process	The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.
GO:0007616	long-term memory	biological_process	The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
GO:0007617	mating behavior	biological_process	The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
GO:0007618	mating	biological_process	The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.
GO:0007619	courtship behavior	biological_process	The behavior of an organism for the purpose of attracting sexual partners.
GO:0007620	copulation	biological_process	The act of sexual union between male and female, involving the transfer of sperm.
GO:0007621	negative regulation of female receptivity	biological_process	Any process that stops, prevents or reduces the receptiveness of a female to male advances.
GO:0007622	rhythmic behavior	biological_process	The specific behavior of an organism that recur with measured regularity.
GO:0007623	circadian rhythm	biological_process	Any biological process in an organism that recurs with a regularity of approximately 24 hours.
GO:0007624	ultradian rhythm	biological_process	The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.
GO:0007625	grooming behavior	biological_process	The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
GO:0007626	locomotory behavior	biological_process	The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
GO:0007628	adult walking behavior	biological_process	The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
GO:0007629	flight behavior	biological_process	The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
GO:0007630	jump response	biological_process	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.
GO:0007631	feeding behavior	biological_process	Behavior associated with the intake of food.
GO:0007632	visual behavior	biological_process	The behavior of an organism in response to a visual stimulus.
GO:0007633	pattern orientation	biological_process	The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes.
GO:0007634	optokinetic behavior	biological_process	The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.
GO:0007635	chemosensory behavior	biological_process	Behavior that is dependent upon the sensation of chemicals.
GO:0007636	chemosensory jump behavior	biological_process	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance.
GO:0007637	proboscis extension reflex	biological_process	The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.
GO:0007638	mechanosensory behavior	biological_process	Behavior that is dependent upon the sensation of a mechanical stimulus.
GO:0007639	homeostasis of number of meristem cells	biological_process	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.
GO:0008009	chemokine activity	molecular_function	The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0008010	structural constituent of chitin-based larval cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.
GO:0008011	structural constituent of pupal chitin-based cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster.
GO:0008012	structural constituent of adult chitin-based cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.
GO:0008013	beta-catenin binding	molecular_function	Binding to a catenin beta subunit.
GO:0008015	blood circulation	biological_process	The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.
GO:0008016	regulation of heart contraction	biological_process	Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
GO:0008017	microtubule binding	molecular_function	Binding to a microtubule, a filament composed of tubulin monomers.
GO:0008020	G protein-coupled photoreceptor activity	molecular_function	Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0008021	synaptic vesicle	cellular_component	A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
GO:0008023	transcription elongation factor complex	cellular_component	Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
GO:0008024	cyclin/CDK positive transcription elongation factor complex	cellular_component	A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.
GO:0008028	monocarboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
GO:0008029	pentraxin receptor activity	molecular_function	Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0008030	neuronal pentraxin receptor activity	molecular_function	Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0008031	eclosion hormone activity	molecular_function	The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis.
GO:0008033	tRNA processing	biological_process	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
GO:0008035	high-density lipoprotein particle binding	molecular_function	Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.
GO:0008036	diuretic hormone receptor activity	molecular_function	Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.
GO:0008037	cell recognition	biological_process	The process in which a cell in an organism interprets its surroundings.
GO:0008038	neuron recognition	biological_process	The process in which a neuronal cell in a multicellular organism interprets its surroundings.
GO:0008039	synaptic target recognition	biological_process	The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.
GO:0008043	intracellular ferritin complex	cellular_component	A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains.
GO:0008045	motor neuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
GO:0008046	axon guidance receptor activity	molecular_function	Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
GO:0008047	enzyme activator activity	molecular_function	Binds to and increases the activity of an enzyme.
GO:0008048	calcium sensitive guanylate cyclase activator activity	molecular_function	Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.
GO:0008049	male courtship behavior	biological_process	The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
GO:0008050	female courtship behavior	biological_process	The behavior of a female, for the purpose of attracting a sexual partner.
GO:0008052	sensory organ boundary specification	biological_process	The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.
GO:0008053	mitochondrial fusion	biological_process	Merging of two or more mitochondria within a cell to form a single compartment.
GO:0008055	ocellus pigment biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
GO:0008056	ocellus development	biological_process	The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.
GO:0008057	eye pigment granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.
GO:0008058	ocellus pigment granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.
GO:0008061	chitin binding	molecular_function	Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0008062	eclosion rhythm	biological_process	The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.
GO:0008063	Toll signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0008064	regulation of actin polymerization or depolymerization	biological_process	Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
GO:0008065	establishment of blood-nerve barrier	biological_process	The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier.
GO:0008066	glutamate receptor activity	molecular_function	Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0008068	extracellularly glutamate-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium	biological_process	Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster.
GO:0008070	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded	biological_process	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line.
GO:0008071	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded	biological_process	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.
GO:0008073	ornithine decarboxylase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of ornithine decarboxylase.
GO:0008074	guanylate cyclase complex, soluble	cellular_component	Complex that possesses guanylate cyclase activity and is not bound to a membrane.
GO:0008076	voltage-gated potassium channel complex	cellular_component	A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
GO:0008078	mesodermal cell migration	biological_process	The orderly movement of mesodermal cells from one site to another.
GO:0008079	translation termination factor activity	molecular_function	Functions in the termination of translation.
GO:0008080	N-acetyltransferase activity	molecular_function	Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.
GO:0008081	phosphoric diester hydrolase activity	molecular_function	Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
GO:0008083	growth factor activity	molecular_function	The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
GO:0008084	imaginal disc growth factor receptor binding	molecular_function	Binding to an imaginal disc growth factor receptor.
GO:0008086	light-activated voltage-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0008087	light-activated voltage-gated calcium channel complex	cellular_component	A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.
GO:0008088	axo-dendritic transport	biological_process	The directed movement of organelles or molecules along microtubules in neuron projections.
GO:0008089	anterograde axonal transport	biological_process	The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
GO:0008090	retrograde axonal transport	biological_process	The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.
GO:0008091	spectrin	cellular_component	Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.
GO:0008092	cytoskeletal protein binding	molecular_function	Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
GO:0008093	cytoskeletal anchor activity	molecular_function	The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way.
GO:0008094	ATP-dependent activity, acting on DNA	molecular_function	Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.
GO:0008096	juvenile hormone epoxide hydrolase activity	molecular_function	Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.
GO:0008097	5S rRNA binding	molecular_function	Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
GO:0008098	5S rRNA primary transcript binding	molecular_function	Binding to an unprocessed 5S ribosomal RNA transcript.
GO:0008103	oocyte microtubule cytoskeleton polarization	biological_process	Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.
GO:0008104	protein localization	biological_process	Any process in which a protein is transported to, or maintained in, a specific location.
GO:0008106	alcohol dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.
GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
GO:0008110	L-histidine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.
GO:0008111	alpha-methylacyl-CoA racemase activity	molecular_function	Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.
GO:0008112	nicotinamide N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.
GO:0008113	peptide-methionine (S)-S-oxide reductase activity	molecular_function	Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0008114	phosphogluconate 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.
GO:0008115	sarcosine oxidase activity	molecular_function	Catalysis of the reaction: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2.
GO:0008116	prostaglandin-I synthase activity	molecular_function	Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).
GO:0008117	sphinganine-1-phosphate aldolase activity	molecular_function	Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.
GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein + H+.
GO:0008119	thiopurine S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
GO:0008120	ceramide glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.
GO:0008121	ubiquinol-cytochrome-c reductase activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+.
GO:0008123	cholesterol 7-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.
GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	molecular_function	Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.
GO:0008126	acetylesterase activity	molecular_function	Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.
GO:0008127	quercetin 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: H+ + O2 + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.
GO:0008131	primary amine oxidase activity	molecular_function	Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
GO:0008134	transcription factor binding	molecular_function	Binding to a transcription factor, a protein required to initiate or regulate transcription.
GO:0008135	translation factor activity, RNA binding	molecular_function	Functions during translation by binding to RNA during polypeptide synthesis at the ribosome.
GO:0008137	NADH dehydrogenase (ubiquinone) activity	molecular_function	Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) <=> NAD+ + ubiquinol + 4 H+(out).
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	molecular_function	Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
GO:0008139	nuclear localization sequence binding	molecular_function	Binding to a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.
GO:0008140	cAMP response element binding protein binding	molecular_function	Binding to a cAMP response element binding protein (a CREB protein).
GO:0008142	oxysterol binding	molecular_function	Binding to oxysterol, an oxidized form of cholesterol.
GO:0008143	poly(A) binding	molecular_function	Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
GO:0008145	phenylalkylamine binding	molecular_function	Binding to phenylalkylamine or one of its derivatives.
GO:0008146	sulfotransferase activity	molecular_function	Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.
GO:0008147	structural constituent of bone	molecular_function	The action of a molecule that contributes to the structural integrity of bone.
GO:0008150	biological_process	biological_process	A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0008152	metabolic process	biological_process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008153	para-aminobenzoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.
GO:0008154	actin polymerization or depolymerization	biological_process	Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
GO:0008156	negative regulation of DNA replication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.
GO:0008157	protein phosphatase 1 binding	molecular_function	Binding to a protein phosphatase 1.
GO:0008158	hedgehog receptor activity	molecular_function	Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.
GO:0008160	protein tyrosine phosphatase activator activity	molecular_function	Binds to and increases the activity of a phosphotyrosine phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.
GO:0008168	methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0008169	C-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.
GO:0008170	N-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.
GO:0008171	O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
GO:0008172	S-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
GO:0008173	RNA methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
GO:0008174	mRNA methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.
GO:0008175	tRNA methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
GO:0008177	succinate dehydrogenase (ubiquinone) activity	molecular_function	Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
GO:0008179	adenylate cyclase binding	molecular_function	Binding to an adenylate cyclase.
GO:0008180	COP9 signalosome	cellular_component	A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
GO:0008184	glycogen phosphorylase activity	molecular_function	Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
GO:0008186	ATP-dependent activity, acting on RNA	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
GO:0008187	poly-pyrimidine tract binding	molecular_function	Binding to a stretch of pyrimidines (cytosine or uracil) in an RNA molecule.
GO:0008188	neuropeptide receptor activity	molecular_function	Combining with a neuropeptide to initiate a change in cell activity.
GO:0008190	eukaryotic initiation factor 4E binding	molecular_function	Binding to eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
GO:0008191	metalloendopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
GO:0008192	RNA guanylyltransferase activity	molecular_function	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
GO:0008193	tRNA guanylyltransferase activity	molecular_function	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.
GO:0008194	UDP-glycosyltransferase activity	molecular_function	Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.
GO:0008195	phosphatidate phosphatase activity	molecular_function	Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
GO:0008196	vitellogenin receptor activity	molecular_function	Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.
GO:0008198	ferrous iron binding	molecular_function	Binding to a ferrous iron ion, Fe(II).
GO:0008199	ferric iron binding	molecular_function	Binding to a ferric iron ion, Fe(III).
GO:0008200	ion channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of an ion channel.
GO:0008201	heparin binding	molecular_function	Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0008202	steroid metabolic process	biological_process	The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:0008203	cholesterol metabolic process	biological_process	The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
GO:0008204	ergosterol metabolic process	biological_process	The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.
GO:0008205	ecdysone metabolic process	biological_process	The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.
GO:0008206	bile acid metabolic process	biological_process	The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
GO:0008207	C21-steroid hormone metabolic process	biological_process	The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
GO:0008208	C21-steroid hormone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
GO:0008209	androgen metabolic process	biological_process	The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
GO:0008210	estrogen metabolic process	biological_process	The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
GO:0008211	glucocorticoid metabolic process	biological_process	The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
GO:0008212	mineralocorticoid metabolic process	biological_process	The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.
GO:0008213	protein alkylation	biological_process	The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.
GO:0008214	protein dealkylation	biological_process	The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.
GO:0008215	spermine metabolic process	biological_process	The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
GO:0008216	spermidine metabolic process	biological_process	The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0008217	regulation of blood pressure	biological_process	Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
GO:0008218	bioluminescence	biological_process	The production of light by certain enzyme-catalyzed reactions in cells.
GO:0008219	cell death	biological_process	Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GO:0008226	tyramine receptor activity	molecular_function	Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.
GO:0008227	G protein-coupled amine receptor activity	molecular_function	Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0008228	opsonization	biological_process	The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.
GO:0008230	ecdysone receptor holocomplex	cellular_component	A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.
GO:0008231	repressor ecdysone receptor complex	cellular_component	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.
GO:0008232	activator ecdysone receptor complex	cellular_component	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.
GO:0008233	peptidase activity	molecular_function	Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0008234	cysteine-type peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008235	metalloexopeptidase activity	molecular_function	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0008236	serine-type peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0008237	metallopeptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0008238	exopeptidase activity	molecular_function	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.
GO:0008239	dipeptidyl-peptidase activity	molecular_function	Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.
GO:0008240	tripeptidyl-peptidase activity	molecular_function	Catalysis of the release of an N-terminal tripeptide from a polypeptide.
GO:0008241	peptidyl-dipeptidase activity	molecular_function	Catalysis of the release of C-terminal dipeptides from a polypeptide chain.
GO:0008242	omega peptidase activity	molecular_function	Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.
GO:0008247	1-alkyl-2-acetylglycerophosphocholine esterase complex	cellular_component	An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF).
GO:0008250	oligosaccharyltransferase complex	cellular_component	A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected.
GO:0008251	tRNA-specific adenosine deaminase activity	molecular_function	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.
GO:0008252	nucleotidase activity	molecular_function	Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.
GO:0008253	5'-nucleotidase activity	molecular_function	Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
GO:0008254	3'-nucleotidase activity	molecular_function	Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
GO:0008255	ecdysis-triggering hormone activity	molecular_function	The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.
GO:0008256	protein histidine pros-kinase activity	molecular_function	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.
GO:0008257	protein histidine tele-kinase activity	molecular_function	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.
GO:0008258	head involution	biological_process	Movement of the anterior ectoderm to the interior of the embryo.
GO:0008260	succinyl-CoA:3-oxo-acid CoA-transferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA.
GO:0008261	allatostatin receptor activity	molecular_function	Combining with allatostatin to initiate a change in cell activity.
GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	molecular_function	Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
GO:0008265	Mo-molybdopterin cofactor sulfurase activity	molecular_function	Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase.
GO:0008266	poly(U) RNA binding	molecular_function	Binding to a sequence of uracil residues in an RNA molecule.
GO:0008267	poly-glutamine tract binding	molecular_function	Binding to a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.
GO:0008269	JAK pathway signal transduction adaptor activity	molecular_function	The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way.
GO:0008270	zinc ion binding	molecular_function	Binding to a zinc ion (Zn).
GO:0008271	secondary active sulfate transmembrane transporter activity	molecular_function	Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0008272	sulfate transport	biological_process	The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0008273	calcium, potassium:sodium antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).
GO:0008275	gamma-tubulin small complex	cellular_component	A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.
GO:0008276	protein methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group (CH3-) to a protein.
GO:0008277	regulation of G protein-coupled receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
GO:0008278	cohesin complex	cellular_component	A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
GO:0008281	sulfonylurea receptor activity	molecular_function	Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0008282	inward rectifying potassium channel	cellular_component	A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.
GO:0008283	cell population proliferation	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population.
GO:0008284	positive regulation of cell population proliferation	biological_process	Any process that activates or increases the rate or extent of cell proliferation.
GO:0008285	negative regulation of cell population proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of cell proliferation.
GO:0008286	insulin receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
GO:0008287	protein serine/threonine phosphatase complex	cellular_component	A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.
GO:0008288	boss receptor activity	molecular_function	Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
GO:0008289	lipid binding	molecular_function	Binding to a lipid.
GO:0008290	F-actin capping protein complex	cellular_component	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.
GO:0008291	acetylcholine metabolic process	biological_process	The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
GO:0008292	acetylcholine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.
GO:0008293	torso signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity	molecular_function	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
GO:0008295	spermidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0008296	3'-5'-DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule.
GO:0008298	intracellular mRNA localization	biological_process	Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
GO:0008299	isoprenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0008300	isoprenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0008301	DNA binding, bending	molecular_function	The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0008302	female germline ring canal formation, actin assembly	biological_process	Recruitment and organization of actin filaments in female germline ring canals.
GO:0008303	caspase complex	cellular_component	A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.
GO:0008305	integrin complex	cellular_component	A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
GO:0008306	associative learning	biological_process	Learning by associating a stimulus (the cause) with a particular outcome (the effect).
GO:0008307	structural constituent of muscle	molecular_function	The action of a molecule that contributes to the structural integrity of a muscle fiber.
GO:0008308	voltage-gated monoatomic anion channel activity	molecular_function	Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0008309	double-stranded DNA exodeoxyribonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.
GO:0008310	single-stranded DNA 3'-5' DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
GO:0008311	double-stranded DNA 3'-5' DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.
GO:0008312	7S RNA binding	molecular_function	Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).
GO:0008315	G2/MI transition of meiotic cell cycle	biological_process	The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I.
GO:0008316	structural constituent of vitelline membrane	molecular_function	The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster.
GO:0008318	protein prenyltransferase activity	molecular_function	Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.
GO:0008320	protein transmembrane transporter activity	molecular_function	Enables the transfer of a protein from one side of a membrane to the other.
GO:0008324	monoatomic cation transmembrane transporter activity	molecular_function	Enables the transfer of cation from one side of a membrane to the other.
GO:0008327	methyl-CpG binding	molecular_function	Binding to a methylated cytosine/guanine dinucleotide.
GO:0008328	ionotropic glutamate receptor complex	cellular_component	A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
GO:0008330	protein tyrosine/threonine phosphatase activity	molecular_function	Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
GO:0008331	high voltage-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
GO:0008332	low voltage-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.
GO:0008333	endosome to lysosome transport	biological_process	The directed movement of substances from endosomes to lysosomes.
GO:0008334	histone mRNA metabolic process	biological_process	The chemical reactions and pathways involving an mRNA encoding a histone.
GO:0008335	female germline ring canal stabilization	biological_process	Maintenance of the structural integrity of the ring canals connecting the female germline cyst.
GO:0008336	gamma-butyrobetaine dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O2 = carnitine + CO2 + succinate.
GO:0008340	determination of adult lifespan	biological_process	The pathways that regulate the duration of the adult phase of the life-cycle of an animal.
GO:0008343	adult feeding behavior	biological_process	Feeding behavior in a fully developed and mature organism.
GO:0008344	adult locomotory behavior	biological_process	Locomotory behavior in a fully developed and mature organism.
GO:0008345	larval locomotory behavior	biological_process	Locomotory behavior in a larval (immature) organism.
GO:0008346	larval walking behavior	biological_process	The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
GO:0008347	glial cell migration	biological_process	The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
GO:0008348	negative regulation of antimicrobial humoral response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.
GO:0008349	MAP kinase kinase kinase kinase activity	molecular_function	Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.
GO:0008352	katanin complex	cellular_component	A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.
GO:0008354	germ cell migration	biological_process	The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
GO:0008355	olfactory learning	biological_process	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
GO:0008356	asymmetric cell division	biological_process	The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
GO:0008358	maternal determination of anterior/posterior axis, embryo	biological_process	The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.
GO:0008359	regulation of bicoid mRNA localization	biological_process	Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
GO:0008360	regulation of cell shape	biological_process	Any process that modulates the surface configuration of a cell.
GO:0008361	regulation of cell size	biological_process	Any process that modulates the size of a cell.
GO:0008362	chitin-based embryonic cuticle biosynthetic process	biological_process	Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.
GO:0008363	larval chitin-based cuticle development	biological_process	Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
GO:0008364	pupal chitin-based cuticle development	biological_process	Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster.
GO:0008365	adult chitin-based cuticle development	biological_process	Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.
GO:0008366	axon ensheathment	biological_process	Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
GO:0008373	sialyltransferase activity	molecular_function	Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
GO:0008374	O-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.
GO:0008375	acetylglucosaminyltransferase activity	molecular_function	Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.
GO:0008376	acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.
GO:0008377	light-induced release of internally sequestered calcium ion	biological_process	The process in which the detection of light triggers the release of internally sequestered calcium ions.
GO:0008378	galactosyltransferase activity	molecular_function	Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0008379	thioredoxin peroxidase activity	molecular_function	Catalysis of the reaction: [thioredoxin]-dithiol + hydrogen peroxide = [thioredoxin]-disulfide + H2O.
GO:0008380	RNA splicing	biological_process	The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
GO:0008381	mechanosensitive monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress.
GO:0008384	IkappaB kinase activity	molecular_function	Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.
GO:0008385	IkappaB kinase complex	cellular_component	A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity	molecular_function	Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.
GO:0008387	steroid 7-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O.
GO:0008388	testosterone 15-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O.
GO:0008389	coumarin 7-hydroxylase activity	molecular_function	Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.
GO:0008390	testosterone 16-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.
GO:0008391	arachidonic acid monooxygenase activity	molecular_function	Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
GO:0008392	arachidonic acid epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
GO:0008395	steroid hydroxylase activity	molecular_function	Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
GO:0008396	oxysterol 7-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O.
GO:0008397	sterol 12-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.
GO:0008398	sterol 14-demethylase activity	molecular_function	Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].
GO:0008399	naphthalene hydroxylase activity	molecular_function	Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide.
GO:0008401	retinoic acid 4-hydroxylase activity	molecular_function	Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.
GO:0008404	arachidonic acid 14,15-epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid.
GO:0008405	arachidonic acid 11,12-epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.
GO:0008406	gonad development	biological_process	The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
GO:0008407	chaeta morphogenesis	biological_process	The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
GO:0008408	3'-5' exonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
GO:0008409	5'-3' exonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.
GO:0008410	CoA-transferase activity	molecular_function	Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor).
GO:0008411	4-hydroxybutyrate CoA-transferase activity	molecular_function	Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.
GO:0008412	4-hydroxybenzoate octaprenyltransferase activity	molecular_function	Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	molecular_function	Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
GO:0008414	CDP-alcohol phosphotransferase activity	molecular_function	Catalysis of the transfer of a CDP-alcohol group from one compound to another.
GO:0008417	fucosyltransferase activity	molecular_function	Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0008418	protein-N-terminal asparagine amidohydrolase activity	molecular_function	Catalysis of the reaction: N-terminal L-asparaginyl-[protein] + H+ + H2O = N-terminal L-aspartyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.
GO:0008419	RNA lariat debranching enzyme activity	molecular_function	Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine/threonine (consensus YSPTSPS) + H2O = RNA polymerase II large subunit + phosphate.
GO:0008421	long-chain fatty-acyl-glutamate deacylase activity	molecular_function	Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.
GO:0008422	beta-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity	molecular_function	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+.
GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0008426	protein kinase C inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein.
GO:0008427	calcium-dependent protein kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase.
GO:0008428	ribonuclease inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of ribonuclease.
GO:0008429	phosphatidylethanolamine binding	molecular_function	Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
GO:0008430	selenium binding	molecular_function	Binding to a selenium (Se) ion.
GO:0008431	vitamin E binding	molecular_function	Binding to a vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
GO:0008432	JUN kinase binding	molecular_function	Binding to JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.
GO:0008437	thyrotropin-releasing hormone activity	molecular_function	The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H+.
GO:0008441	3'(2'),5'-bisphosphate nucleotidase activity	molecular_function	Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.
GO:0008442	3-hydroxyisobutyrate dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
GO:0008443	phosphofructokinase activity	molecular_function	Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule.
GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H+.
GO:0008445	D-aspartate oxidase activity	molecular_function	Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide.
GO:0008446	GDP-mannose 4,6-dehydratase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O.
GO:0008447	L-ascorbate oxidase activity	molecular_function	Catalysis of the reaction: 4 L-ascorbate + O2 <=> 4 monodehydroascorbate + 2 H2O.
GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
GO:0008449	N-acetylglucosamine-6-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.
GO:0008452	RNA ligase activity	molecular_function	Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.
GO:0008453	alanine-glyoxylate transaminase activity	molecular_function	Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.
GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.
GO:0008455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
GO:0008456	alpha-N-acetylgalactosaminidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.
GO:0008457	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.
GO:0008458	carnitine O-octanoyltransferase activity	molecular_function	Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.
GO:0008459	chondroitin 6-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
GO:0008460	dTDP-glucose 4,6-dehydratase activity	molecular_function	Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.
GO:0008463	formylmethionine deformylase activity	molecular_function	Catalysis of the reaction: N-formyl-L-methionine + H2O = L-methionine + formate.
GO:0008465	glycerate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.
GO:0008466	glycogenin glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.
GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
GO:0008469	histone arginine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.
GO:0008470	isovaleryl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein].
GO:0008473	ornithine cyclodeaminase activity	molecular_function	Catalysis of the reaction: L-ornithine = L-proline + NH4.
GO:0008474	palmitoyl-(protein) hydrolase activity	molecular_function	Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.
GO:0008475	procollagen-lysine 5-dioxygenase activity	molecular_function	Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.
GO:0008476	protein-tyrosine sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
GO:0008477	purine nucleosidase activity	molecular_function	Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.
GO:0008478	pyridoxal kinase activity	molecular_function	Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
GO:0008479	tRNA-guanosine(34) queuine transglycosylase activity	molecular_function	Catalysis of the reaction: guanosine34 in tRNA + queuine = guanine + queuosine34 in tRNA.
GO:0008480	sarcosine dehydrogenase activity	molecular_function	Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.
GO:0008481	sphinganine kinase activity	molecular_function	Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate.
GO:0008482	sulfite oxidase activity	molecular_function	Catalysis of the reaction: H2O + O2 + sulfite = H2O2 + H+ + sulfate.
GO:0008483	transaminase activity	molecular_function	Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
GO:0008484	sulfuric ester hydrolase activity	molecular_function	Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2.
GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: diphospho-1D-myo-inositol polyphosphate + H2O = 1D-myo-inositol polyphosphate + phosphate.
GO:0008488	gamma-glutamyl carboxylase activity	molecular_function	Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide.
GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base.
GO:0008490	arsenite secondary active transmembrane transporter activity	molecular_function	Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0008493	tetracycline transmembrane transporter activity	molecular_function	Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
GO:0008494	translation activator activity	molecular_function	Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.
GO:0008495	protoheme IX farnesyltransferase activity	molecular_function	Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.
GO:0008496	mannan endo-1,6-alpha-mannosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.
GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.
GO:0008502	melatonin receptor activity	molecular_function	Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.
GO:0008503	benzodiazepine receptor activity	molecular_function	Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.
GO:0008504	monoamine transmembrane transporter activity	molecular_function	Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.
GO:0008506	sucrose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).
GO:0008507	sodium:iodide symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).
GO:0008508	bile acid:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).
GO:0008509	monoatomic anion transmembrane transporter activity	molecular_function	Enables the transfer of a negatively charged ion from one side of a membrane to the other.
GO:0008510	sodium:bicarbonate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
GO:0008511	sodium:potassium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).
GO:0008512	sulfate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in).
GO:0008513	secondary active organic cation transmembrane transporter activity	molecular_function	Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GO:0008514	organic anion transmembrane transporter activity	molecular_function	Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GO:0008515	sucrose transmembrane transporter activity	molecular_function	Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.
GO:0008516	hexose uniporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in).
GO:0008517	folic acid transmembrane transporter activity	molecular_function	Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GO:0008518	folate:monoatomic anion antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.
GO:0008519	ammonium transmembrane transporter activity	molecular_function	Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
GO:0008520	L-ascorbate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).
GO:0008521	acetyl-CoA transmembrane transporter activity	molecular_function	Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
GO:0008523	sodium-dependent multivitamin transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate.
GO:0008525	phosphatidylcholine transporter activity	molecular_function	Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0008526	phosphatidylinositol transfer activity	molecular_function	Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0008527	taste receptor activity	molecular_function	Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.
GO:0008528	G protein-coupled peptide receptor activity	molecular_function	Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0008531	riboflavin kinase activity	molecular_function	Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H+.
GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity	molecular_function	Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
GO:0008535	respiratory chain complex IV assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
GO:0008537	proteasome activator complex	cellular_component	A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.
GO:0008540	proteasome regulatory particle, base subcomplex	cellular_component	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex.
GO:0008541	proteasome regulatory particle, lid subcomplex	cellular_component	The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.
GO:0008542	visual learning	biological_process	Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
GO:0008543	fibroblast growth factor receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
GO:0008544	epidermis development	biological_process	The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
GO:0008545	JUN kinase kinase activity	molecular_function	Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.
GO:0008551	P-type cadmium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) = ADP + phosphate + Cd2+(out).
GO:0008553	P-type proton-exporting transporter activity	molecular_function	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
GO:0008554	P-type sodium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.
GO:0008556	P-type potassium transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in).
GO:0008558	ABC-type guanine transporter activity	molecular_function	Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).
GO:0008559	ABC-type xenobiotic transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
GO:0008564	protein-exporting ATPase activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.
GO:0008566	mitochondrial protein-transporting ATPase activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.
GO:0008568	microtubule severing ATPase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.
GO:0008569	minus-end-directed microtubule motor activity	molecular_function	A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.
GO:0008574	plus-end-directed microtubule motor activity	molecular_function	A motor activity that generates movement along a microtubule toward the plus end, driven by ATP hydrolysis.
GO:0008579	JUN kinase phosphatase activity	molecular_function	Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.
GO:0008582	regulation of synaptic assembly at neuromuscular junction	biological_process	Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions.
GO:0008583	mystery cell differentiation	biological_process	The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.
GO:0008584	male gonad development	biological_process	The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
GO:0008585	female gonad development	biological_process	The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
GO:0008586	imaginal disc-derived wing vein morphogenesis	biological_process	The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.
GO:0008587	imaginal disc-derived wing margin morphogenesis	biological_process	The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.
GO:0008589	regulation of smoothened signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of smoothened signaling.
GO:0008591	regulation of Wnt signaling pathway, calcium modulating pathway	biological_process	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
GO:0008592	regulation of Toll signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the Tl signaling pathway.
GO:0008593	regulation of Notch signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
GO:0008594	photoreceptor cell morphogenesis	biological_process	The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.
GO:0008595	anterior/posterior axis specification, embryo	biological_process	The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	molecular_function	Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.
GO:0008603	cAMP-dependent protein kinase regulator activity	molecular_function	Modulation of the activity of the enzyme cAMP-dependent protein kinase.
GO:0008607	phosphorylase kinase regulator activity	molecular_function	Modulation of the activity of the enzyme phosphorylase kinase.
GO:0008608	attachment of spindle microtubules to kinetochore	biological_process	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.
GO:0008609	alkylglycerone-phosphate synthase activity	molecular_function	Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
GO:0008610	lipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0008611	ether lipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	biological_process	The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
GO:0008613	diuretic hormone activity	molecular_function	The action characteristic of a diuretic hormone, a peptide hormone that, upon receptor binding, regulates water balance and fluid secretion.
GO:0008614	pyridoxine metabolic process	biological_process	The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0008615	pyridoxine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
GO:0008616	queuosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
GO:0008617	guanosine metabolic process	biological_process	The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.
GO:0008618	7-methylguanosine metabolic process	biological_process	The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
GO:0008622	epsilon DNA polymerase complex	cellular_component	A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.
GO:0008623	CHRAC	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	biological_process	The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.
GO:0008626	granzyme-mediated apoptotic signaling pathway	biological_process	The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.
GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
GO:0008628	hormone-mediated apoptotic signaling pathway	biological_process	The series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	biological_process	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
GO:0008637	apoptotic mitochondrial changes	biological_process	The morphological and physiological alterations undergone by mitochondria during apoptosis.
GO:0008641	ubiquitin-like modifier activating enzyme activity	molecular_function	Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0008643	carbohydrate transport	biological_process	The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.
GO:0008645	hexose transmembrane transport	biological_process	The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.
GO:0008649	rRNA methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
GO:0008650	rRNA (uridine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.
GO:0008652	amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
GO:0008653	lipopolysaccharide metabolic process	biological_process	The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
GO:0008654	phospholipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.
GO:0008655	pyrimidine-containing compound salvage	biological_process	Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	molecular_function	Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.
GO:0008657	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0008658	penicillin binding	molecular_function	Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0008659	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O.
GO:0008660	1-aminocyclopropane-1-carboxylate deaminase activity	molecular_function	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanate + NH4.
GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H+ + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2.
GO:0008662	1-phosphofructokinase activity	molecular_function	Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.
GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity	molecular_function	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
GO:0008664	2'-5'-RNA ligase activity	molecular_function	Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another.
GO:0008666	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity	molecular_function	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.
GO:0008667	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity	molecular_function	Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ = 2,3-dihydroxybenzoate + H+ + NADH.
GO:0008668	(2,3-dihydroxybenzoyl)adenylate synthase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate.
GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity	molecular_function	Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.
GO:0008671	2-dehydro-3-deoxygalactonokinase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H+.
GO:0008672	2-dehydro-3-deoxyglucarate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.
GO:0008673	2-dehydro-3-deoxygluconokinase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H+.
GO:0008674	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity	molecular_function	Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate.
GO:0008675	2-dehydro-3-deoxy-phosphogluconate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.
GO:0008676	3-deoxy-8-phosphooctulonate synthase activity	molecular_function	Catalysis of the reaction: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H+ + phosphate.
GO:0008677	2-dehydropantoate 2-reductase activity	molecular_function	Catalysis of the reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + H+ + NADPH.
GO:0008678	2-deoxy-D-gluconate 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.
GO:0008679	2-hydroxy-3-oxopropionate reductase activity	molecular_function	Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.
GO:0008681	2-octaprenyl-6-methoxyphenol hydroxylase activity	molecular_function	Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.
GO:0008682	3-demethoxyubiquinol 3-hydroxylase activity	molecular_function	Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O.
GO:0008683	2-oxoglutarate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + H+ = CO2 + succinate semialdehyde.
GO:0008684	2-oxopent-4-enoate hydratase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.
GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	molecular_function	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.
GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	molecular_function	Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H+.
GO:0008687	3,4-dihydroxyphenylacetate 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O2 = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H+.
GO:0008688	3-(3-hydroxyphenyl)propionate hydroxylase activity	molecular_function	Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.
GO:0008689	3-demethylubiquinone-9 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.
GO:0008690	3-deoxy-manno-octulosonate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.
GO:0008691	3-hydroxybutyryl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.
GO:0008692	3-hydroxybutyryl-CoA epimerase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
GO:0008693	(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.
GO:0008694	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	molecular_function	Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2.
GO:0008695	3-phenylpropionate dioxygenase activity	molecular_function	Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.
GO:0008696	4-amino-4-deoxychorismate lyase activity	molecular_function	Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H+ + pyruvate.
GO:0008697	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity	molecular_function	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.
GO:0008700	4-hydroxy-2-oxoglutarate aldolase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
GO:0008701	4-hydroxy-2-oxovalerate aldolase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.
GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	molecular_function	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + H+ + NADPH.
GO:0008704	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity	molecular_function	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.
GO:0008705	methionine synthase activity	molecular_function	Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.
GO:0008706	6-phospho-beta-glucosidase activity	molecular_function	Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.
GO:0008707	4-phytase activity	molecular_function	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.
GO:0008709	cholate 7-alpha-dehydrogenase activity	molecular_function	Catalysis of the reaction: cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H+ + NADH.
GO:0008710	8-amino-7-oxononanoate synthase activity	molecular_function	Catalysis of the reaction: L-alanine + H+ + pimelyl-CoA = 8-amino-7-oxononanoate + CO2 + CoA.
GO:0008712	ADP-glyceromanno-heptose 6-epimerase activity	molecular_function	Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.
GO:0008713	ADP-heptose-lipopolysaccharide heptosyltransferase activity	molecular_function	Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.
GO:0008714	AMP nucleosidase activity	molecular_function	Catalysis of the reaction: AMP + H2O = D-ribose 5-phosphate + adenine.
GO:0008715	CDP-diacylglycerol diphosphatase activity	molecular_function	Catalysis of the reaction: CDP-diacylglycerol + H2O = a phosphatidate + CMP + 2 H+.
GO:0008716	D-alanine-D-alanine ligase activity	molecular_function	Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H+ + phosphate.
GO:0008718	D-amino-acid dehydrogenase activity	molecular_function	Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor.
GO:0008719	dihydroneopterin triphosphate 2'-epimerase activity	molecular_function	Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.
GO:0008720	D-lactate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-lactate + NAD+ = H+ + NADH + pyruvate.
GO:0008721	D-serine ammonia-lyase activity	molecular_function	Catalysis of the reaction: D-serine = pyruvate + NH3.
GO:0008725	DNA-3-methyladenine glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.
GO:0008726	alkanesulfonate monooxygenase activity	molecular_function	Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.
GO:0008727	GDP-mannose mannosyl hydrolase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+.
GO:0008728	GTP diphosphokinase activity	molecular_function	Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
GO:0008730	L(+)-tartrate dehydratase activity	molecular_function	Catalysis of the reaction: L-tartrate = H2O + oxaloacetate.
GO:0008732	L-allo-threonine aldolase activity	molecular_function	Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.
GO:0008733	L-arabinose isomerase activity	molecular_function	Catalysis of the reaction: L-arabinose = L-ribulose.
GO:0008734	L-aspartate oxidase activity	molecular_function	Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide.
GO:0008735	L-carnitine CoA-transferase activity	molecular_function	Catalysis of the reactions: (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl-CoA and 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.
GO:0008736	L-fucose isomerase activity	molecular_function	Catalysis of the reaction: L-fucose = L-fuculose.
GO:0008737	L-fuculokinase activity	molecular_function	Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H+.
GO:0008738	L-fuculose-phosphate aldolase activity	molecular_function	Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.
GO:0008740	L-rhamnose isomerase activity	molecular_function	Catalysis of the reaction: L-rhamnose = L-rhamnulose.
GO:0008741	ribulokinase activity	molecular_function	Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.
GO:0008742	L-ribulose-phosphate 4-epimerase activity	molecular_function	Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate.
GO:0008743	L-threonine 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + CO2 + NADH.
GO:0008744	L-xylulokinase activity	molecular_function	Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	molecular_function	Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
GO:0008746	NAD(P)+ transhydrogenase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+.
GO:0008747	N-acetylneuraminate lyase activity	molecular_function	Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
GO:0008748	N-ethylmaleimide reductase activity	molecular_function	Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.
GO:0008750	NAD(P)+ transhydrogenase (AB-specific) activity	molecular_function	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.
GO:0008752	FMN reductase (NAD(P)H) activity	molecular_function	Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. This reaction can utilize NADH and NADPH with similar reaction rates.
GO:0008753	NADPH dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.
GO:0008754	O antigen ligase activity	molecular_function	Catalysis of the reaction: Lipid A-core + colanic acid = MLPS.
GO:0008755	O antigen polymerase activity	molecular_function	Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.
GO:0008756	o-succinylbenzoate-CoA ligase activity	molecular_function	Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate.
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
GO:0008758	UDP-2,3-diacylglucosamine hydrolase activity	molecular_function	Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.
GO:0008759	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	molecular_function	Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.
GO:0008760	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	molecular_function	Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.
GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+.
GO:0008763	UDP-N-acetylmuramate-L-alanine ligase activity	molecular_function	Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanine.
GO:0008764	UDP-N-acetylmuramoylalanine-D-glutamate ligase activity	molecular_function	Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.
GO:0008765	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	molecular_function	Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.
GO:0008766	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	molecular_function	Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.
GO:0008767	UDP-galactopyranose mutase activity	molecular_function	Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
GO:0008768	UDP-sugar diphosphatase activity	molecular_function	Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate.
GO:0008770	[acyl-carrier-protein] phosphodiesterase activity	molecular_function	Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.
GO:0008771	[citrate (pro-3S)-lyase] ligase activity	molecular_function	Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form).
GO:0008772	[isocitrate dehydrogenase (NADP+)] kinase activity	molecular_function	Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.
GO:0008773	[protein-PII] uridylyltransferase activity	molecular_function	Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
GO:0008774	acetaldehyde dehydrogenase (acetylating) activity	molecular_function	Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.
GO:0008775	acetate CoA-transferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
GO:0008776	acetate kinase activity	molecular_function	Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.
GO:0008777	acetylornithine deacetylase activity	molecular_function	Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.
GO:0008779	acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.
GO:0008780	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	molecular_function	Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.
GO:0008781	N-acylneuraminate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.
GO:0008782	adenosylhomocysteine nucleosidase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.
GO:0008783	agmatinase activity	molecular_function	Catalysis of the reaction: agmatine + H2O = putrescine + urea.
GO:0008784	alanine racemase activity	molecular_function	Catalysis of the reaction: L-alanine = D-alanine.
GO:0008785	alkyl hydroperoxide reductase activity	molecular_function	Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.
GO:0008786	allose 6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.
GO:0008787	allose kinase activity	molecular_function	Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.
GO:0008788	alpha,alpha-phosphotrehalase activity	molecular_function	Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.
GO:0008789	altronate dehydratase activity	molecular_function	Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O.
GO:0008790	arabinose isomerase activity	molecular_function	Catalysis of the reaction: D-arabinose = D-ribulose.
GO:0008791	arginine N-succinyltransferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.
GO:0008792	arginine decarboxylase activity	molecular_function	Catalysis of the reaction: L-arginine + H+ = agmatine + CO2.
GO:0008793	aromatic-amino-acid:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
GO:0008794	arsenate reductase (glutaredoxin) activity	molecular_function	Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.
GO:0008795	NAD+ synthase activity	molecular_function	Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.
GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity	molecular_function	Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
GO:0008797	aspartate ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-aspartate = fumarate + NH3.
GO:0008798	beta-aspartyl-peptidase activity	molecular_function	Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
GO:0008800	beta-lactamase activity	molecular_function	Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
GO:0008801	beta-phosphoglucomutase activity	molecular_function	Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
GO:0008802	betaine-aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
GO:0008803	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity	molecular_function	Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H+.
GO:0008804	carbamate kinase activity	molecular_function	Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate.
GO:0008805	carbon-monoxide oxygenase activity	molecular_function	Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.
GO:0008806	carboxymethylenebutenolidase activity	molecular_function	Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.
GO:0008807	carboxyvinyl-carboxyphosphonate phosphorylmutase activity	molecular_function	Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.
GO:0008808	cardiolipin synthase activity	molecular_function	Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.
GO:0008809	carnitine racemase activity	molecular_function	Catalysis of the reaction: D-carnitine = L-carnitine.
GO:0008810	cellulase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
GO:0008811	chloramphenicol O-acetyltransferase activity	molecular_function	Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.
GO:0008812	choline dehydrogenase activity	molecular_function	Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.
GO:0008813	chorismate lyase activity	molecular_function	Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate.
GO:0008814	citrate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.
GO:0008815	citrate (pro-3S)-lyase activity	molecular_function	Catalysis of the reaction: citrate = acetate + oxaloacetate.
GO:0008816	citryl-CoA lyase activity	molecular_function	Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.
GO:0008817	corrinoid adenosyltransferase activity	molecular_function	Catalysis of the reaction: 2 ATP + 2 corrinoid + reduced [electron-transfer flavoprotein] = 2 adenosylcorrinoid + 3 H+ + oxidized [electron-transfer flavoprotein] + 2 triphosphate. The corrinoid can be cob(II)yrinate a,c diamide, cob(II)inamide or cob(II)alamin.
GO:0008818	cobalamin 5'-phosphate synthase activity	molecular_function	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP.
GO:0008819	cobinamide kinase activity	molecular_function	Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.
GO:0008820	cobinamide phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H+ = adenosylcobinamide-GDP + diphosphate.
GO:0008821	crossover junction DNA endonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).
GO:0008823	cupric reductase activity	molecular_function	Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH.
GO:0008824	cyanate hydratase activity	molecular_function	Catalysis of the reaction: cyanate + H2O = carbamate.
GO:0008825	cyclopropane-fatty-acyl-phospholipid synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
GO:0008826	cysteine sulfinate desulfinase activity	molecular_function	Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite.
GO:0008828	dATP diphosphatase activity	molecular_function	Catalysis of the reaction: dATP + H2O = dAMP + H+ + diphosphate.
GO:0008829	dCTP deaminase activity	molecular_function	Catalysis of the reaction: dCTP + H2O = dUTP + NH3.
GO:0008830	dTDP-4-dehydrorhamnose 3,5-epimerase activity	molecular_function	Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.
GO:0008831	dTDP-4-dehydrorhamnose reductase activity	molecular_function	Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + H+ + NADPH.
GO:0008832	dGTPase activity	molecular_function	Catalysis of the reaction: dGTP + H2O = 2'-deoxyguanosine + 2 H+ + triphosphate.
GO:0008833	deoxyribonuclease IV (phage-T4-induced) activity	molecular_function	Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.
GO:0008834	di-trans,poly-cis-decaprenylcistransferase activity	molecular_function	Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate.
GO:0008835	diaminohydroxyphosphoribosylaminopyrimidine deaminase activity	molecular_function	Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O + H+ = 5-amino-6-(5-phosphoribosylamino)uracil + NH4.
GO:0008836	diaminopimelate decarboxylase activity	molecular_function	Catalysis of the reaction: meso-2,6-diaminopimelate + H+ = L-lysine + CO2.
GO:0008837	diaminopimelate epimerase activity	molecular_function	Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
GO:0008838	diaminopropionate ammonia-lyase activity	molecular_function	Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.
GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	molecular_function	Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.
GO:0008840	4-hydroxy-tetrahydrodipicolinate synthase activity	molecular_function	Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O.
GO:0008841	dihydrofolate synthase activity	molecular_function	Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate.
GO:0008842	diphosphate-purine nucleoside kinase activity	molecular_function	Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide.
GO:0008843	endochitinase activity	molecular_function	Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.
GO:0008847	Enterobacter ribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
GO:0008849	enterochelin esterase activity	molecular_function	Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.
GO:0008851	ethanolamine ammonia-lyase activity	molecular_function	Catalysis of the reaction: ethanolamine = acetaldehyde + NH3.
GO:0008854	exodeoxyribonuclease V activity	molecular_function	Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.
GO:0008855	exodeoxyribonuclease VII activity	molecular_function	Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.
GO:0008859	exoribonuclease II activity	molecular_function	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.
GO:0008860	ferredoxin-NAD+ reductase activity	molecular_function	Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+.
GO:0008861	formate C-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.
GO:0008863	formate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: formate + NAD+ = CO2 + NADH.
GO:0008864	formyltetrahydrofolate deformylase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H+.
GO:0008865	fructokinase activity	molecular_function	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
GO:0008866	fructuronate reductase activity	molecular_function	Catalysis of the reaction: D-mannonate + NAD+ = D-fructuronate + H+ + NADH.
GO:0008867	galactarate dehydratase activity	molecular_function	Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O.
GO:0008868	galactitol-1-phosphate 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.
GO:0008869	galactonate dehydratase activity	molecular_function	Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O.
GO:0008870	galactoside O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.
GO:0008871	aminoglycoside 2''-nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.
GO:0008872	glucarate dehydratase activity	molecular_function	Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.
GO:0008873	gluconate 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.
GO:0008874	gluconate 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+.
GO:0008875	gluconate dehydrogenase activity	molecular_function	Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+.
GO:0008876	quinoprotein glucose dehydrogenase activity	molecular_function	Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.
GO:0008877	glucose-1-phosphatase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.
GO:0008878	glucose-1-phosphate adenylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.
GO:0008879	glucose-1-phosphate thymidylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose.
GO:0008880	glucuronate isomerase activity	molecular_function	Catalysis of the reaction: D-glucuronate = D-fructuronate.
GO:0008881	glutamate racemase activity	molecular_function	Catalysis of the reaction: L-glutamate = D-glutamate.
GO:0008882	[glutamate-ammonia-ligase] adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].
GO:0008883	glutamyl-tRNA reductase activity	molecular_function	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H+ + NADPH.
GO:0008884	glutathionylspermidine amidase activity	molecular_function	Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.
GO:0008885	glutathionylspermidine synthase activity	molecular_function	Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.
GO:0008886	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H2O + NADP+ = 3-phospho-D-glycerate + 2 H+ + NADPH.
GO:0008887	glycerate kinase activity	molecular_function	Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H+.
GO:0008888	glycerol dehydrogenase [NAD+] activity	molecular_function	Catalysis of the reaction: glycerol + NAD+ = glycerone + H+ + NADH.
GO:0008889	glycerophosphodiester phosphodiesterase activity	molecular_function	Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
GO:0008890	glycine C-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA.
GO:0008892	guanine deaminase activity	molecular_function	Catalysis of the reaction: guanine + H2O = xanthine + NH3.
GO:0008893	guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	molecular_function	Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.
GO:0008894	guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.
GO:0008897	holo-[acyl-carrier-protein] synthase activity	molecular_function	Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.
GO:0008899	homoserine O-succinyltransferase activity	molecular_function	Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA.
GO:0008900	P-type potassium:proton transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
GO:0008901	ferredoxin hydrogenase activity	molecular_function	Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
GO:0008902	hydroxymethylpyrimidine kinase activity	molecular_function	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H+.
GO:0008903	hydroxypyruvate isomerase activity	molecular_function	Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate.
GO:0008904	hygromycin-B 7''-O-phosphotransferase activity	molecular_function	Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H+.
GO:0008906	inosine kinase activity	molecular_function	Catalysis of the reaction: ATP + inosine = ADP + IMP.
GO:0008907	integrase activity	molecular_function	Catalysis of the integration of one DNA segment into another.
GO:0008908	isochorismatase activity	molecular_function	Catalysis of the reaction: H2O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.
GO:0008909	isochorismate synthase activity	molecular_function	Catalysis of the reaction: chorismate = isochorismate.
GO:0008910	kanamycin kinase activity	molecular_function	Catalysis of the reaction: ATP + kanamycin = ADP + 2 H+ + kanamycin 3'-phosphate.
GO:0008911	lactaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.
GO:0008912	lactaldehyde reductase activity	molecular_function	Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.
GO:0008913	lauroyltransferase activity	molecular_function	Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another.
GO:0008914	leucyl-tRNA--protein transferase activity	molecular_function	Catalysis of the reaction: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H+ + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu). Can also transfer the leucyl residue on an N-terminal L-lysyl residue.
GO:0008915	lipid-A-disaccharide synthase activity	molecular_function	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H+ + UDP.
GO:0008917	lipopolysaccharide N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.
GO:0008918	lipopolysaccharide 3-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.
GO:0008919	lipopolysaccharide glucosyltransferase I activity	molecular_function	Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.
GO:0008920	lipopolysaccharide heptosyltransferase activity	molecular_function	Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.
GO:0008921	lipopolysaccharide-1,6-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.
GO:0008922	long-chain fatty acid [acyl-carrier-protein] ligase activity	molecular_function	Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0008923	lysine decarboxylase activity	molecular_function	Catalysis of the reaction: L-lysine + H+ = cadaverine + CO2.
GO:0008924	malate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.
GO:0008925	maltose O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.
GO:0008926	mannitol-1-phosphate 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
GO:0008927	mannonate dehydratase activity	molecular_function	Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.
GO:0008928	mannose-1-phosphate guanylyltransferase (GDP) activity	molecular_function	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H+ = GDP-alpha-D-mannose + phosphate.
GO:0008929	methylglyoxal synthase activity	molecular_function	Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.
GO:0008930	methylthioadenosine nucleosidase activity	molecular_function	Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose.
GO:0008932	lytic endotransglycosylase activity	molecular_function	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.
GO:0008933	lytic transglycosylase activity	molecular_function	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.
GO:0008934	inositol monophosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.
GO:0008935	1,4-dihydroxy-2-naphthoyl-CoA synthase activity	molecular_function	Catalysis of the reaction: 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O.
GO:0008936	nicotinamidase activity	molecular_function	Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.
GO:0008937	ferredoxin-NAD(P) reductase activity	molecular_function	Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.
GO:0008938	nicotinate N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine.
GO:0008939	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H+ + nicotinate.
GO:0008940	nitrate reductase activity	molecular_function	Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.
GO:0008941	nitric oxide dioxygenase activity	molecular_function	Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.
GO:0008942	nitrite reductase [NAD(P)H] activity	molecular_function	Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+.
GO:0008946	oligonucleotidase activity	molecular_function	Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates.
GO:0008948	oxaloacetate decarboxylase activity	molecular_function	Catalysis of the reaction: oxaloacetate = pyruvate + CO2.
GO:0008949	oxalyl-CoA decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + oxalyl-CoA = CO2 + formyl-CoA.
GO:0008951	palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity	molecular_function	Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].
GO:0008953	penicillin amidase activity	molecular_function	Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.
GO:0008955	peptidoglycan glycosyltransferase activity	molecular_function	Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.
GO:0008957	phenylacetaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+.
GO:0008959	phosphate acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.
GO:0008960	phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity	molecular_function	Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.
GO:0008961	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	molecular_function	Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.
GO:0008962	phosphatidylglycerophosphatase activity	molecular_function	Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol.
GO:0008964	phosphoenolpyruvate carboxylase activity	molecular_function	Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.
GO:0008965	phosphoenolpyruvate-protein phosphotransferase activity	molecular_function	Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.
GO:0008966	phosphoglucosamine mutase activity	molecular_function	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.
GO:0008967	phosphoglycolate phosphatase activity	molecular_function	Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate.
GO:0008968	D-sedoheptulose 7-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate.
GO:0008970	phospholipase A1 activity	molecular_function	Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
GO:0008972	phosphomethylpyrimidine kinase activity	molecular_function	Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.
GO:0008973	phosphopentomutase activity	molecular_function	Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate.
GO:0008974	phosphoribulokinase activity	molecular_function	Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H+.
GO:0008976	polyphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).
GO:0008977	prephenate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: NAD+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADH.
GO:0008979	prophage integrase activity	molecular_function	Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA.
GO:0008980	propionate kinase activity	molecular_function	Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.
GO:0008982	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0008983	protein-glutamate O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.
GO:0008984	protein-glutamate methylesterase activity	molecular_function	Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.
GO:0008986	pyruvate, water dikinase activity	molecular_function	Catalysis of the reaction: ATP + H2O + pyruvate = AMP + 3 H+ + phosphate + phosphoenolpyruvate.
GO:0008987	quinolinate synthetase A activity	molecular_function	Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.
GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.
GO:0008989	rRNA (guanine-N1-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.
GO:0008990	rRNA (guanine-N2-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.
GO:0008993	rhamnulokinase activity	molecular_function	Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.
GO:0008994	rhamnulose-1-phosphate aldolase activity	molecular_function	Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.
GO:0008995	ribonuclease E activity	molecular_function	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
GO:0008996	ribonuclease G activity	molecular_function	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
GO:0008997	ribonuclease R activity	molecular_function	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.
GO:0008998	ribonucleoside-triphosphate reductase activity	molecular_function	Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
GO:0008999	peptide-alanine-alpha-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + N-terminal L-alanyl-peptide = CoA + H+ + N-terminal N-alpha-acetyl-L-alanyl-peptide.
GO:0009000	selenocysteine lyase activity	molecular_function	Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.
GO:0009001	serine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.
GO:0009002	serine-type D-Ala-D-Ala carboxypeptidase activity	molecular_function	Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.
GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.
GO:0009008	DNA-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to a DNA molecule.
GO:0009009	site-specific recombinase activity	molecular_function	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences.
GO:0009010	sorbitol-6-phosphate 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
GO:0009011	starch synthase activity	molecular_function	Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1).
GO:0009012	aminoglycoside 3''-adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H+.
GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
GO:0009014	succinyl-diaminopimelate desuccinylase activity	molecular_function	Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + succinate.
GO:0009015	N-succinylarginine dihydrolase activity	molecular_function	Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H2O + 2 H+ = N(2)-succinyl-L-ornithine + CO2 + 2 NH4.
GO:0009016	succinyldiaminopimelate transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate.
GO:0009017	succinylglutamate desuccinylase activity	molecular_function	Catalysis of the reaction: N-succinyl-L-glutamate + H2O = L-glutamate + succinate.
GO:0009018	sucrose phosphorylase activity	molecular_function	Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.
GO:0009019	tRNA (guanine-N1-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
GO:0009020	tRNA (guanosine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine.
GO:0009022	tRNA nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
GO:0009024	tagatose-6-phosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.
GO:0009025	tagatose-bisphosphate aldolase activity	molecular_function	Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate.
GO:0009026	tagaturonate reductase activity	molecular_function	Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.
GO:0009027	tartrate dehydrogenase activity	molecular_function	Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.
GO:0009028	tartronate-semialdehyde synthase activity	molecular_function	Catalysis of the reaction: 2 glyoxylate + H+ = 2-hydroxy-3-oxopropanoate + CO2.
GO:0009029	tetraacyldisaccharide 4'-kinase activity	molecular_function	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H+ + lipid IV(a).
GO:0009030	thiamine-phosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + thiamine phosphate = ADP + H+ + thiamine diphosphate.
GO:0009032	thymidine phosphorylase activity	molecular_function	Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
GO:0009033	trimethylamine-N-oxide reductase activity	molecular_function	Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O.
GO:0009034	tryptophanase activity	molecular_function	Catalysis of the reaction: L-tryptophan + H2O = indole + NH4 + pyruvate.
GO:0009035	type I site-specific deoxyribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
GO:0009036	type II site-specific deoxyribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
GO:0009037	tyrosine-based site-specific recombinase activity	molecular_function	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.
GO:0009038	undecaprenol kinase activity	molecular_function	Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.
GO:0009039	urease activity	molecular_function	Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
GO:0009040	ureidoglycolate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.
GO:0009041	UMP/dUMP kinase activity	molecular_function	Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.
GO:0009042	valine-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
GO:0009044	xylan 1,4-beta-xylosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.
GO:0009045	xylose isomerase activity	molecular_function	Catalysis of the reaction: D-xylose = D-xylulose.
GO:0009046	zinc D-Ala-D-Ala carboxypeptidase activity	molecular_function	Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.
GO:0009047	dosage compensation by hyperactivation of X chromosome	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
GO:0009048	dosage compensation by inactivation of X chromosome	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.
GO:0009050	glycopeptide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.
GO:0009051	pentose-phosphate shunt, oxidative branch	biological_process	The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
GO:0009052	pentose-phosphate shunt, non-oxidative branch	biological_process	The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.
GO:0009055	electron transfer activity	molecular_function	Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
GO:0009056	catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
GO:0009057	macromolecule catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009058	biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0009059	macromolecule biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0009060	aerobic respiration	biological_process	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
GO:0009061	anaerobic respiration	biological_process	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
GO:0009062	fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
GO:0009063	amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
GO:0009064	glutamine family amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
GO:0009065	glutamine family amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
GO:0009066	aspartate family amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
GO:0009067	aspartate family amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
GO:0009068	aspartate family amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
GO:0009069	serine family amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
GO:0009070	serine family amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
GO:0009071	serine family amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
GO:0009072	aromatic amino acid metabolic process	biological_process	The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
GO:0009073	aromatic amino acid family biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
GO:0009074	aromatic amino acid family catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
GO:0009078	pyruvate family amino acid metabolic process	biological_process	The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.
GO:0009079	pyruvate family amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine.
GO:0009080	pyruvate family amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine.
GO:0009081	branched-chain amino acid metabolic process	biological_process	The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
GO:0009082	branched-chain amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
GO:0009083	branched-chain amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
GO:0009084	glutamine family amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
GO:0009085	lysine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
GO:0009086	methionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
GO:0009087	methionine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
GO:0009088	threonine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
GO:0009089	lysine biosynthetic process via diaminopimelate	biological_process	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
GO:0009090	homoserine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.
GO:0009091	homoserine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid.
GO:0009092	homoserine metabolic process	biological_process	The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
GO:0009093	cysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid.
GO:0009094	L-phenylalanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.
GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	biological_process	The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate.
GO:0009097	isoleucine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
GO:0009098	leucine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
GO:0009099	valine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
GO:0009100	glycoprotein metabolic process	biological_process	The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0009101	glycoprotein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0009102	biotin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
GO:0009103	lipopolysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
GO:0009104	lipopolysaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
GO:0009106	lipoate metabolic process	biological_process	The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
GO:0009107	lipoate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
GO:0009110	vitamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0009111	vitamin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0009112	nucleobase metabolic process	biological_process	The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.
GO:0009113	purine nucleobase biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
GO:0009114	hypoxanthine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
GO:0009115	xanthine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
GO:0009116	nucleoside metabolic process	biological_process	The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
GO:0009117	nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
GO:0009118	regulation of nucleoside metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GO:0009119	ribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0009120	deoxyribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0009123	nucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
GO:0009124	nucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
GO:0009125	nucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
GO:0009126	purine nucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009127	purine nucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009128	purine nucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009131	pyrimidine nucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
GO:0009132	nucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
GO:0009133	nucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
GO:0009134	nucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
GO:0009135	purine nucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009136	purine nucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009137	purine nucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009138	pyrimidine nucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009139	pyrimidine nucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009140	pyrimidine nucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009141	nucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
GO:0009142	nucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
GO:0009143	nucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
GO:0009144	purine nucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009145	purine nucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009146	purine nucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009149	pyrimidine nucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009150	purine ribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009151	purine deoxyribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009152	purine ribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009153	purine deoxyribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009154	purine ribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009155	purine deoxyribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009156	ribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009158	ribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009159	deoxyribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009161	ribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009162	deoxyribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009163	nucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0009164	nucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0009165	nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
GO:0009166	nucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
GO:0009167	purine ribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009169	purine ribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009170	purine deoxyribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009171	purine deoxyribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009172	purine deoxyribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009175	pyrimidine ribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009178	pyrimidine deoxyribonucleoside monophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
GO:0009179	purine ribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009180	purine ribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009181	purine ribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009182	purine deoxyribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009183	purine deoxyribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009184	purine deoxyribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009185	ribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009186	deoxyribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009187	cyclic nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
GO:0009188	ribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009189	deoxyribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009190	cyclic nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
GO:0009191	ribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009192	deoxyribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009193	pyrimidine ribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009194	pyrimidine ribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009195	pyrimidine ribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
GO:0009196	pyrimidine deoxyribonucleoside diphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009197	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009198	pyrimidine deoxyribonucleoside diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
GO:0009199	ribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009200	deoxyribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009201	ribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009203	ribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009204	deoxyribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009205	purine ribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009207	purine ribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009210	pyrimidine ribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009212	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009213	pyrimidine deoxyribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009214	cyclic nucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	biological_process	The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009216	purine deoxyribonucleoside triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
GO:0009218	pyrimidine ribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009220	pyrimidine ribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009222	pyrimidine ribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009224	CMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.
GO:0009225	nucleotide-sugar metabolic process	biological_process	The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0009226	nucleotide-sugar biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0009227	nucleotide-sugar catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0009228	thiamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0009229	thiamine diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
GO:0009230	thiamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0009231	riboflavin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
GO:0009232	riboflavin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
GO:0009233	menaquinone metabolic process	biological_process	The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
GO:0009234	menaquinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
GO:0009235	cobalamin metabolic process	biological_process	The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GO:0009236	cobalamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GO:0009237	siderophore metabolic process	biological_process	The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
GO:0009238	enterobactin metabolic process	biological_process	The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
GO:0009239	enterobactin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
GO:0009240	isopentenyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
GO:0009242	colanic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.
GO:0009243	O antigen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
GO:0009244	lipopolysaccharide core region biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.
GO:0009245	lipid A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.
GO:0009246	enterobacterial common antigen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
GO:0009247	glycolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
GO:0009248	K antigen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.
GO:0009249	protein lipoylation	biological_process	The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.
GO:0009250	glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
GO:0009251	glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.
GO:0009252	peptidoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
GO:0009253	peptidoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
GO:0009254	peptidoglycan turnover	biological_process	The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall.
GO:0009255	Entner-Doudoroff pathway through 6-phosphogluconate	biological_process	A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.
GO:0009256	10-formyltetrahydrofolate metabolic process	biological_process	The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
GO:0009257	10-formyltetrahydrofolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
GO:0009258	10-formyltetrahydrofolate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
GO:0009259	ribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009260	ribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009261	ribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009262	deoxyribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009263	deoxyribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009264	deoxyribonucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009265	2'-deoxyribonucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009266	response to temperature stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
GO:0009267	cellular response to starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
GO:0009268	response to pH	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0009269	response to desiccation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
GO:0009270	response to humidity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.
GO:0009271	phage shock	biological_process	A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.
GO:0009272	fungal-type cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.
GO:0009273	peptidoglycan-based cell wall biogenesis	biological_process	The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli.
GO:0009274	peptidoglycan-based cell wall	cellular_component	A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.
GO:0009275	Gram-positive-bacterium-type cell wall	cellular_component	A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria.
GO:0009276	Gram-negative-bacterium-type cell wall	cellular_component	The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain.
GO:0009277	fungal-type cell wall	cellular_component	A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
GO:0009279	cell outer membrane	cellular_component	A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
GO:0009288	bacterial-type flagellum	cellular_component	A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
GO:0009289	pilus	cellular_component	A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
GO:0009290	DNA import into cell involved in transformation	biological_process	The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.
GO:0009291	unidirectional conjugation	biological_process	The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells. Some or all of the chromosome(s) of the donor cell is transferred into the recipient cell.
GO:0009292	horizontal gene transfer	biological_process	The introduction of genetic information into a cell to create a genetically different individual, without production of new individuals.
GO:0009293	transduction	biological_process	A type of horizontal gene transfer in which genetic material is introduced into a cell mediated by a virus.
GO:0009294	DNA-mediated transformation	biological_process	The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.
GO:0009295	nucleoid	cellular_component	The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
GO:0009297	pilus assembly	biological_process	The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles.
GO:0009298	GDP-mannose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
GO:0009299	mRNA transcription	biological_process	The cellular synthesis of messenger RNA (mRNA) from a DNA template.
GO:0009300	antisense RNA transcription	biological_process	The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
GO:0009301	snRNA transcription	biological_process	The synthesis of small nuclear RNA (snRNA) from a DNA template.
GO:0009302	sno(s)RNA transcription	biological_process	The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template.
GO:0009303	rRNA transcription	biological_process	The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
GO:0009304	tRNA transcription	biological_process	The synthesis of transfer RNA (tRNA) from a DNA template.
GO:0009306	protein secretion	biological_process	The controlled release of proteins from a cell.
GO:0009307	DNA restriction-modification system	biological_process	A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.
GO:0009308	amine metabolic process	biological_process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GO:0009309	amine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GO:0009310	amine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GO:0009311	oligosaccharide metabolic process	biological_process	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
GO:0009312	oligosaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
GO:0009313	oligosaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
GO:0009314	response to radiation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
GO:0009316	3-isopropylmalate dehydratase complex	cellular_component	A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
GO:0009317	acetyl-CoA carboxylase complex	cellular_component	A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
GO:0009318	exodeoxyribonuclease VII complex	cellular_component	An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.
GO:0009319	cytochrome o ubiquinol oxidase complex	cellular_component	A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups.
GO:0009320	phosphoribosylaminoimidazole carboxylase complex	cellular_component	A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity.
GO:0009321	alkyl hydroperoxide reductase complex	cellular_component	An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.
GO:0009322	trimethylamine-N-oxide reductase complex	cellular_component	An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine.
GO:0009324	D-amino-acid dehydrogenase complex	cellular_component	A protein complex that possesses D-amino-acid dehydrogenase activity.
GO:0009325	nitrate reductase complex	cellular_component	An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.
GO:0009326	formate dehydrogenase complex	cellular_component	An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).
GO:0009328	phenylalanine-tRNA ligase complex	cellular_component	An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).
GO:0009329	acetate CoA-transferase complex	cellular_component	A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA.
GO:0009330	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	cellular_component	Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity.
GO:0009331	glycerol-3-phosphate dehydrogenase complex	cellular_component	An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.
GO:0009332	glutamate-tRNA ligase complex	cellular_component	An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu).
GO:0009333	cysteine synthase complex	cellular_component	Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.
GO:0009334	3-phenylpropionate dioxygenase complex	cellular_component	Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).
GO:0009336	sulfate adenylyltransferase complex (ATP)	cellular_component	An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.
GO:0009337	sulfite reductase complex (NADPH)	cellular_component	A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.
GO:0009338	exodeoxyribonuclease V complex	cellular_component	An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.
GO:0009339	glycolate oxidase complex	cellular_component	An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN).
GO:0009340	DNA topoisomerase IV complex	cellular_component	A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA.
GO:0009341	beta-galactosidase complex	cellular_component	A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
GO:0009342	glutamate synthase complex (NADPH)	cellular_component	A complex that possesses glutamate synthase (NADPH) activity.
GO:0009344	nitrite reductase complex [NAD(P)H]	cellular_component	Complex that possesses nitrite reductase [NAD(P)H] activity.
GO:0009345	glycine-tRNA ligase complex	cellular_component	A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly).
GO:0009346	ATP-independent citrate lyase complex	cellular_component	Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. This enzyme has only been found in bacteria.
GO:0009347	aspartate carbamoyltransferase complex	cellular_component	A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.
GO:0009349	riboflavin synthase complex	cellular_component	An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.
GO:0009350	ethanolamine ammonia-lyase complex	cellular_component	An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.
GO:0009353	mitochondrial oxoglutarate dehydrogenase complex	cellular_component	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.
GO:0009355	DNA polymerase V complex	cellular_component	A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.
GO:0009356	aminodeoxychorismate synthase complex	cellular_component	A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity.
GO:0009357	protein-N(PI)-phosphohistidine-sugar phosphotransferase complex	cellular_component	An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system.
GO:0009358	polyphosphate kinase complex	cellular_component	A protein complex that possesses polyphosphate kinase activity.
GO:0009359	type II site-specific deoxyribonuclease complex	cellular_component	A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
GO:0009360	DNA polymerase III complex	cellular_component	The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
GO:0009361	succinate-CoA ligase complex (ADP-forming)	cellular_component	A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP.
GO:0009365	protein histidine kinase complex	cellular_component	A complex that possesses protein histidine kinase activity.
GO:0009366	enterobactin synthetase complex	cellular_component	A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway.
GO:0009368	endopeptidase Clp complex	cellular_component	A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
GO:0009372	quorum sensing	biological_process	The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.
GO:0009374	biotin binding	molecular_function	Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
GO:0009375	ferredoxin hydrogenase complex	cellular_component	An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.
GO:0009376	HslUV protease complex	cellular_component	A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.
GO:0009378	four-way junction helicase activity	molecular_function	Unwinding a DNA helix of DNA containing four-way junctions, including Holliday junctions, driven by ATP hydrolysis.
GO:0009379	Holliday junction helicase complex	cellular_component	A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.
GO:0009380	excinuclease repair complex	cellular_component	Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.
GO:0009381	excinuclease ABC activity	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind.
GO:0009382	imidazoleglycerol-phosphate synthase complex	cellular_component	Complex that possesses imidazoleglycerol-phosphate synthase activity.
GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.
GO:0009384	N-acylmannosamine kinase activity	molecular_function	Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.
GO:0009385	N-acylmannosamine-6-phosphate 2-epimerase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate.
GO:0009386	translational attenuation	biological_process	Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation.
GO:0009389	dimethyl sulfoxide reductase activity	molecular_function	Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O.
GO:0009390	dimethyl sulfoxide reductase complex	cellular_component	An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide.
GO:0009392	N-acetyl-anhydromuramoyl-L-alanine amidase activity	molecular_function	Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.
GO:0009394	2'-deoxyribonucleotide metabolic process	biological_process	The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009395	phospholipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0009396	folic acid-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
GO:0009397	folic acid-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.
GO:0009398	FMN biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
GO:0009399	nitrogen fixation	biological_process	The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.
GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	biological_process	The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
GO:0009403	toxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0009404	toxin metabolic process	biological_process	The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0009407	toxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0009408	response to heat	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0009409	response to cold	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
GO:0009410	response to xenobiotic stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0009411	response to UV	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GO:0009413	response to flooding	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.
GO:0009414	response to water deprivation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
GO:0009415	response to water	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
GO:0009416	response to light stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
GO:0009418	pilus shaft	cellular_component	The long, slender, mid section of a pilus.
GO:0009419	pilus tip	cellular_component	The pointed extremity furthest from the cell of a pilus.
GO:0009420	bacterial-type flagellum filament	cellular_component	The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller.
GO:0009421	bacterial-type flagellum filament cap	cellular_component	The proteinaceous structure at the distal tip of the bacterial-type flagellar filament.
GO:0009422	bacterial-type flagellum hook-filament junction	cellular_component	The region of the bacterial-type flagellum where the hook and filament meet.
GO:0009423	chorismate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
GO:0009424	bacterial-type flagellum hook	cellular_component	The portion of the bacterial-type flagellum that connects the filament to the basal body.
GO:0009425	bacterial-type flagellum basal body	cellular_component	One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.
GO:0009426	bacterial-type flagellum basal body, distal rod	cellular_component	The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes.
GO:0009427	bacterial-type flagellum basal body, distal rod, L ring	cellular_component	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane.
GO:0009428	bacterial-type flagellum basal body, distal rod, P ring	cellular_component	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer.
GO:0009429	bacterial-type flagellum basal body, proximal rod	cellular_component	The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor.
GO:0009431	bacterial-type flagellum basal body, MS ring	cellular_component	One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane.
GO:0009432	SOS response	biological_process	An error-prone process for repairing damaged microbial DNA.
GO:0009433	bacterial-type flagellum basal body, C ring	cellular_component	Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise.
GO:0009435	NAD biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0009436	glyoxylate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
GO:0009437	carnitine metabolic process	biological_process	The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
GO:0009438	methylglyoxal metabolic process	biological_process	The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
GO:0009439	cyanate metabolic process	biological_process	The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid.
GO:0009440	cyanate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.
GO:0009441	glycolate metabolic process	biological_process	The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).
GO:0009442	allantoin assimilation pathway	biological_process	The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.
GO:0009443	pyridoxal 5'-phosphate salvage	biological_process	Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.
GO:0009444	pyruvate oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate.
GO:0009445	putrescine metabolic process	biological_process	The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.
GO:0009446	putrescine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
GO:0009447	putrescine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.
GO:0009448	gamma-aminobutyric acid metabolic process	biological_process	The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
GO:0009449	gamma-aminobutyric acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
GO:0009450	gamma-aminobutyric acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
GO:0009451	RNA modification	biological_process	The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
GO:0009452	7-methylguanosine RNA capping	biological_process	The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.
GO:0009453	energy taxis	biological_process	The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.
GO:0009454	aerotaxis	biological_process	The directed movement of a motile cell or organism in response to environmental oxygen.
GO:0009455	redox taxis	biological_process	The directed movement of a motile cell or organism in response to redox potential.
GO:0009486	cytochrome bo3 ubiquinol oxidase activity	molecular_function	Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].
GO:0009496	plastoquinol--plastocyanin reductase activity	molecular_function	Catalysis of the reaction: 2 H+[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H+[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane.
GO:0009501	amyloplast	cellular_component	A plastid whose main function is to synthesize and store starch.
GO:0009503	thylakoid light-harvesting complex	cellular_component	A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana.
GO:0009504	cell plate	cellular_component	The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.
GO:0009505	plant-type cell wall	cellular_component	A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
GO:0009506	plasmodesma	cellular_component	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
GO:0009507	chloroplast	cellular_component	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009508	plastid chromosome	cellular_component	A circular DNA molecule containing plastid encoded genes.
GO:0009509	chromoplast	cellular_component	A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.
GO:0009510	plasmodesmatal desmotubule	cellular_component	A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell.
GO:0009511	plasmodesmatal endoplasmic reticulum	cellular_component	Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells.
GO:0009512	cytochrome b6f complex	cellular_component	Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
GO:0009513	etioplast	cellular_component	A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.
GO:0009514	glyoxysome	cellular_component	A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.
GO:0009515	granal stacked thylakoid	cellular_component	Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II.
GO:0009516	leucoplast	cellular_component	A colorless plastid involved in the synthesis of monoterpenes.
GO:0009517	PSII associated light-harvesting complex II	cellular_component	Protein-pigment complex associated with photosystem II.
GO:0009518	PSI associated light-harvesting complex I	cellular_component	Protein-pigment complex associated with photosystem I.
GO:0009519	middle lamella	cellular_component	Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells.
GO:0009521	photosystem	cellular_component	A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species.
GO:0009522	photosystem I	cellular_component	A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation).
GO:0009523	photosystem II	cellular_component	A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.
GO:0009524	phragmoplast	cellular_component	The phragmoplast is a plant cell specific cytoplasmic structure composed of cytoskeletal polymers, membranes, and associated cytosolic proteins that functions as the focused secretory module for assembling the cell plate.
GO:0009525	phragmosome	cellular_component	A flattened membranous vesicle containing cell wall components.
GO:0009526	plastid envelope	cellular_component	The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0009527	plastid outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.
GO:0009528	plastid inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma.
GO:0009529	plastid intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of the plastid envelope.
GO:0009530	primary cell wall	cellular_component	A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present.
GO:0009531	secondary cell wall	cellular_component	A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.
GO:0009532	plastid stroma	cellular_component	The proteinaceous ground substance of plastids.
GO:0009533	chloroplast stromal thylakoid	cellular_component	Unstacked thylakoids that connect the grana stacks through the stroma.
GO:0009534	chloroplast thylakoid	cellular_component	Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.
GO:0009535	chloroplast thylakoid membrane	cellular_component	The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
GO:0009536	plastid	cellular_component	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GO:0009537	proplastid	cellular_component	The precursor of other plastids.
GO:0009538	photosystem I reaction center	cellular_component	A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.
GO:0009539	photosystem II reaction center	cellular_component	An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone.
GO:0009541	etioplast prolamellar body	cellular_component	A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast.
GO:0009542	granum	cellular_component	Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis.
GO:0009543	chloroplast thylakoid lumen	cellular_component	The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.
GO:0009544	chloroplast ATP synthase complex	cellular_component	The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts.
GO:0009545	elaioplast	cellular_component	A leucoplast in which oil is stored.
GO:0009546	plasmodesmatal cytoplasmic sleeve	cellular_component	The space between the plasma membrane and the desmotubule of a plasmodesma.
GO:0009547	plastid ribosome	cellular_component	A ribosome contained within a plastid.
GO:0009548	plasmodesmatal plasma membrane	cellular_component	The portion of the plasma membrane surrounding a plasmodesma.
GO:0009549	cellulose microfibril	cellular_component	A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell.
GO:0009550	primary plasmodesma	cellular_component	A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.
GO:0009551	secondary plasmodesma	cellular_component	A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata.
GO:0009553	embryo sac development	biological_process	The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
GO:0009554	megasporogenesis	biological_process	The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.
GO:0009555	pollen development	biological_process	The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
GO:0009556	microsporogenesis	biological_process	The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.
GO:0009557	antipodal cell differentiation	biological_process	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.
GO:0009558	embryo sac cellularization	biological_process	The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana.
GO:0009559	embryo sac central cell differentiation	biological_process	The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.
GO:0009560	embryo sac egg cell differentiation	biological_process	The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.
GO:0009561	megagametogenesis	biological_process	The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center.
GO:0009562	embryo sac nuclear migration	biological_process	The directed movement of an embryo sac nucleus to the pole or center of the cell.
GO:0009563	synergid differentiation	biological_process	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.
GO:0009566	fertilization	biological_process	The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GO:0009567	double fertilization forming a zygote and endosperm	biological_process	Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
GO:0009568	amyloplast starch grain	cellular_component	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
GO:0009569	chloroplast starch grain	cellular_component	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
GO:0009570	chloroplast stroma	cellular_component	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
GO:0009571	proplastid stroma	cellular_component	The space enclosed by the double membrane of a proplastid.
GO:0009573	chloroplast ribulose bisphosphate carboxylase complex	cellular_component	A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana.
GO:0009574	preprophase band	cellular_component	A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.
GO:0009575	chromoplast stroma	cellular_component	The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material.
GO:0009576	leucoplast stroma	cellular_component	The space enclosed by the double membrane of a leucoplast.
GO:0009577	elaioplast stroma	cellular_component	The space enclosed by the double membrane of an elaioplast.
GO:0009578	etioplast stroma	cellular_component	The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA.
GO:0009579	thylakoid	cellular_component	A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
GO:0009581	detection of external stimulus	biological_process	The series of events in which an external stimulus is received by a cell and converted into a molecular signal.
GO:0009582	detection of abiotic stimulus	biological_process	The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.
GO:0009583	detection of light stimulus	biological_process	The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
GO:0009584	detection of visible light	biological_process	The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
GO:0009585	red, far-red light phototransduction	biological_process	The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
GO:0009588	UV-A, blue light phototransduction	biological_process	The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm.
GO:0009589	detection of UV	biological_process	The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GO:0009590	detection of gravity	biological_process	The series of events in which a gravitational stimulus is received and converted into a molecular signal.
GO:0009593	detection of chemical stimulus	biological_process	The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
GO:0009594	detection of nutrient	biological_process	The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal.
GO:0009595	detection of biotic stimulus	biological_process	The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.
GO:0009597	detection of virus	biological_process	The series of events in which a stimulus from a virus is received and converted into a molecular signal.
GO:0009600	detection of nematode	biological_process	The series of events in which a stimulus from a nematode is received and converted into a molecular signal.
GO:0009601	detection of insect	biological_process	The series of events in which a stimulus from an insect is received and converted into a molecular signal.
GO:0009602	detection of symbiont	biological_process	The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0009603	detection of symbiotic fungus	biological_process	The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal.
GO:0009604	detection of symbiotic bacterium	biological_process	The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.
GO:0009605	response to external stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0009606	tropism	biological_process	The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.
GO:0009607	response to biotic stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0009608	response to symbiont	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0009609	response to symbiotic bacterium	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.
GO:0009610	response to symbiotic fungus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.
GO:0009611	response to wounding	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GO:0009612	response to mechanical stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
GO:0009615	response to virus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
GO:0009616	RNAi-mediated antiviral immune response	biological_process	A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination.
GO:0009617	response to bacterium	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
GO:0009620	response to fungus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
GO:0009624	response to nematode	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
GO:0009625	response to insect	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.
GO:0009626	plant-type hypersensitive response	biological_process	The rapid, localized death of plant cells in response to invasion by a pathogen.
GO:0009627	systemic acquired resistance	biological_process	The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
GO:0009628	response to abiotic stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
GO:0009629	response to gravity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.
GO:0009630	gravitropism	biological_process	The orientation of plant parts under the stimulation of gravity.
GO:0009631	cold acclimation	biological_process	Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
GO:0009635	response to herbicide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
GO:0009636	response to toxic substance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0009637	response to blue light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
GO:0009638	phototropism	biological_process	The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.
GO:0009639	response to red or far red light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0009640	photomorphogenesis	biological_process	The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.
GO:0009641	shade avoidance	biological_process	Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome.
GO:0009642	response to light intensity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
GO:0009643	photosynthetic acclimation	biological_process	A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.
GO:0009644	response to high light intensity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
GO:0009645	response to low light intensity stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
GO:0009646	response to absence of light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
GO:0009647	skotomorphogenesis	biological_process	The control of plant growth, development, and differentiation in response to growth in darkness.
GO:0009648	photoperiodism	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
GO:0009649	entrainment of circadian clock	biological_process	The synchronization of a circadian rhythm to environmental time cues such as light.
GO:0009650	UV protection	biological_process	Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.
GO:0009651	response to salt stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0009652	thigmotropism	biological_process	The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.
GO:0009653	anatomical structure morphogenesis	biological_process	The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
GO:0009654	photosystem II oxygen evolving complex	cellular_component	A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ).
GO:0009655	PSII associated light-harvesting complex II, core complex	cellular_component	The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.
GO:0009656	PSII associated light-harvesting complex II, peripheral complex	cellular_component	Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light.
GO:0009657	plastid organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.
GO:0009658	chloroplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
GO:0009659	leucoplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.
GO:0009660	amyloplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.
GO:0009661	chromoplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.
GO:0009662	etioplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.
GO:0009663	plasmodesma organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
GO:0009664	plant-type cell wall organization	biological_process	A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.
GO:0009665	plastid inheritance	biological_process	The partitioning of plastids between daughter cells at cell division.
GO:0009666	plastid outer membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.
GO:0009667	plastid inner membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.
GO:0009668	plastid membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.
GO:0009669	sucrose:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in).
GO:0009670	triose-phosphate:phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out).
GO:0009671	nitrate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).
GO:0009672	auxin:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in).
GO:0009673	low-affinity phosphate transmembrane transporter activity	molecular_function	Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0009674	potassium:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in).
GO:0009675	high-affinity sulfate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0009676	low-affinity sulfate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0009677	double fertilization forming two zygotes	biological_process	Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.
GO:0009678	diphosphate hydrolysis-driven proton transmembrane transporter activity	molecular_function	Catalysis of the reaction: diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate.
GO:0009679	hexose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).
GO:0009682	induced systemic resistance	biological_process	A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.
GO:0009683	indoleacetic acid metabolic process	biological_process	The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants.
GO:0009684	indoleacetic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
GO:0009685	gibberellin metabolic process	biological_process	The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
GO:0009686	gibberellin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
GO:0009687	abscisic acid metabolic process	biological_process	The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
GO:0009688	abscisic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
GO:0009689	induction of phytoalexin biosynthetic process	biological_process	The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.
GO:0009690	cytokinin metabolic process	biological_process	The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
GO:0009691	cytokinin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
GO:0009692	ethylene metabolic process	biological_process	The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
GO:0009693	ethylene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
GO:0009694	jasmonic acid metabolic process	biological_process	The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.
GO:0009695	jasmonic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.
GO:0009696	salicylic acid metabolic process	biological_process	The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
GO:0009697	salicylic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
GO:0009698	phenylpropanoid metabolic process	biological_process	The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.
GO:0009699	phenylpropanoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.
GO:0009700	indole phytoalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.
GO:0009701	isoflavonoid phytoalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0009702	L-arabinokinase activity	molecular_function	Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H+.
GO:0009703	nitrate reductase (NADH) activity	molecular_function	Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.
GO:0009704	de-etiolation	biological_process	The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.
GO:0009705	plant-type vacuole membrane	cellular_component	The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
GO:0009706	chloroplast inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.
GO:0009707	chloroplast outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope.
GO:0009708	benzyl isoquinoline alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.
GO:0009709	terpenoid indole alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).
GO:0009710	tropane alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.
GO:0009711	purine alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.
GO:0009712	catechol-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.
GO:0009713	catechol-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.
GO:0009714	chalcone metabolic process	biological_process	The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives.
GO:0009715	chalcone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.
GO:0009716	flavonoid phytoalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0009717	isoflavonoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
GO:0009718	anthocyanin-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.
GO:0009719	response to endogenous stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GO:0009720	detection of hormone stimulus	biological_process	The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.
GO:0009721	detection of auxin stimulus	biological_process	The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.
GO:0009722	detection of cytokinin stimulus	biological_process	The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.
GO:0009723	response to ethylene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
GO:0009724	detection of abscisic acid stimulus	biological_process	The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal.
GO:0009725	response to hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
GO:0009726	detection of endogenous stimulus	biological_process	The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.
GO:0009727	detection of ethylene stimulus	biological_process	The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.
GO:0009728	detection of gibberellic acid stimulus	biological_process	The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.
GO:0009729	detection of brassinosteroid stimulus	biological_process	The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.
GO:0009730	detection of carbohydrate stimulus	biological_process	The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal.
GO:0009731	detection of sucrose stimulus	biological_process	The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.
GO:0009732	detection of hexose stimulus	biological_process	The series of events in which a stimulus from a hexose is received and converted into a molecular signal.
GO:0009733	response to auxin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
GO:0009734	auxin-activated signaling pathway	biological_process	The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
GO:0009735	response to cytokinin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
GO:0009736	cytokinin-activated signaling pathway	biological_process	The series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0009737	response to abscisic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
GO:0009738	abscisic acid-activated signaling pathway	biological_process	The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
GO:0009739	response to gibberellin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
GO:0009740	gibberellic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of gibberellic acid.
GO:0009741	response to brassinosteroid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
GO:0009742	brassinosteroid mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of brassinosteroid.
GO:0009743	response to carbohydrate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
GO:0009744	response to sucrose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
GO:0009745	sucrose mediated signaling	biological_process	The series of molecular signals mediated by the detection of sucrose.
GO:0009746	response to hexose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.
GO:0009747	hexokinase-dependent signaling	biological_process	The series of molecular signals mediated by hexose and dependent on the detection of hexokinase.
GO:0009748	hexokinase-independent signaling	biological_process	The series of molecular signals mediated by hexose and independent of hexokinase.
GO:0009749	response to glucose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
GO:0009750	response to fructose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
GO:0009751	response to salicylic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
GO:0009752	detection of salicylic acid stimulus	biological_process	The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.
GO:0009753	response to jasmonic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
GO:0009754	detection of jasmonic acid stimulus	biological_process	The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.
GO:0009755	hormone-mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of a hormone.
GO:0009756	carbohydrate mediated signaling	biological_process	The series of molecular signals mediated by the detection of carbohydrate.
GO:0009757	hexose mediated signaling	biological_process	The series of molecular signals mediated by the detection of hexose.
GO:0009758	carbohydrate utilization	biological_process	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.
GO:0009759	indole glucosinolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
GO:0009760	C4 photosynthesis	biological_process	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.
GO:0009761	CAM photosynthesis	biological_process	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.
GO:0009762	NADP-malic enzyme C4 photosynthesis	biological_process	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.
GO:0009763	NAD-malic enzyme C4 photosynthesis	biological_process	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme.
GO:0009764	PEP carboxykinase C4 photosynthesis	biological_process	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).
GO:0009765	photosynthesis, light harvesting	biological_process	Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.
GO:0009767	photosynthetic electron transport chain	biological_process	A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.
GO:0009768	photosynthesis, light harvesting in photosystem I	biological_process	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.
GO:0009769	photosynthesis, light harvesting in photosystem II	biological_process	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.
GO:0009772	photosynthetic electron transport in photosystem II	biological_process	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I.
GO:0009773	photosynthetic electron transport in photosystem I	biological_process	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.
GO:0009777	photosynthetic phosphorylation	biological_process	Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation.
GO:0009778	cyclic photosynthetic phosphorylation	biological_process	A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.
GO:0009779	noncyclic photosynthetic phosphorylation	biological_process	A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II.
GO:0009780	photosynthetic NADP+ reduction	biological_process	An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.
GO:0009782	photosystem I antenna complex	cellular_component	The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).
GO:0009783	photosystem II antenna complex	cellular_component	The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).
GO:0009784	transmembrane receptor histidine kinase activity	molecular_function	Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
GO:0009785	blue light signaling pathway	biological_process	The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
GO:0009786	regulation of asymmetric cell division	biological_process	Any process that modulates the frequency, rate or extent of asymmetric cell division.
GO:0009787	regulation of abscisic acid-activated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.
GO:0009788	negative regulation of abscisic acid-activated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
GO:0009789	positive regulation of abscisic acid-activated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.
GO:0009790	embryo development	biological_process	The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GO:0009791	post-embryonic development	biological_process	The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
GO:0009792	embryo development ending in birth or egg hatching	biological_process	The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
GO:0009793	embryo development ending in seed dormancy	biological_process	The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
GO:0009794	regulation of mitotic cell cycle, embryonic	biological_process	Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.
GO:0009798	axis specification	biological_process	The establishment, maintenance and elaboration of a pattern along a line or around a point.
GO:0009799	specification of symmetry	biological_process	The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.
GO:0009800	cinnamic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
GO:0009801	cinnamic acid ester metabolic process	biological_process	The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.
GO:0009802	cinnamic acid ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.
GO:0009803	cinnamic acid metabolic process	biological_process	The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.
GO:0009804	coumarin metabolic process	biological_process	The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
GO:0009805	coumarin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.
GO:0009806	lignan metabolic process	biological_process	The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
GO:0009807	lignan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
GO:0009808	lignin metabolic process	biological_process	The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.
GO:0009809	lignin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
GO:0009810	stilbene metabolic process	biological_process	The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA.
GO:0009811	stilbene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.
GO:0009812	flavonoid metabolic process	biological_process	The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.
GO:0009813	flavonoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
GO:0009815	1-aminocyclopropane-1-carboxylate oxidase activity	molecular_function	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + dehydroascorbate + ethylene + 2 H2O + hydrogen cyanide. Ethene is also known as ethylene.
GO:0009819	drought recovery	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.
GO:0009820	alkaloid metabolic process	biological_process	The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).
GO:0009821	alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).
GO:0009822	alkaloid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).
GO:0009823	cytokinin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.
GO:0009824	AMP dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.
GO:0009825	multidimensional cell growth	biological_process	The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.
GO:0009826	unidimensional cell growth	biological_process	The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.
GO:0009827	plant-type cell wall modification	biological_process	The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.
GO:0009828	plant-type cell wall loosening	biological_process	The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.
GO:0009829	cell wall modification involved in fruit ripening	biological_process	The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.
GO:0009830	cell wall modification involved in abscission	biological_process	A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.
GO:0009831	plant-type cell wall modification involved in multidimensional cell growth	biological_process	The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.
GO:0009832	plant-type cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.
GO:0009833	plant-type primary cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.
GO:0009834	plant-type secondary cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
GO:0009835	fruit ripening	biological_process	An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.
GO:0009836	fruit ripening, climacteric	biological_process	A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.
GO:0009837	fruit ripening, non-climacteric	biological_process	A fruit ripening process that does not involve a respiratory burst.
GO:0009838	abscission	biological_process	The controlled shedding of a body part.
GO:0009840	chloroplastic endopeptidase Clp complex	cellular_component	A Clp endopeptidase complex located in the chloroplast.
GO:0009841	mitochondrial endopeptidase Clp complex	cellular_component	A Clp endopeptidase complex located in the mitochondrion.
GO:0009842	cyanelle	cellular_component	A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.
GO:0009843	cyanelle thylakoid	cellular_component	A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.
GO:0009845	seed germination	biological_process	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
GO:0009846	pollen germination	biological_process	The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
GO:0009847	spore germination	biological_process	The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).
GO:0009848	indoleacetic acid biosynthetic process via tryptophan	biological_process	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan.
GO:0009849	tryptophan-independent indoleacetic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan.
GO:0009850	auxin metabolic process	biological_process	The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.
GO:0009851	auxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
GO:0009852	auxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.
GO:0009853	photorespiration	biological_process	A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.
GO:0009854	oxidative photosynthetic carbon pathway	biological_process	The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).
GO:0009855	determination of bilateral symmetry	biological_process	The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
GO:0009856	pollination	biological_process	The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.
GO:0009859	pollen hydration	biological_process	The process in which water is taken up by pollen.
GO:0009860	pollen tube growth	biological_process	Growth of pollen via tip extension of the intine wall.
GO:0009861	jasmonic acid and ethylene-dependent systemic resistance	biological_process	The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
GO:0009862	systemic acquired resistance, salicylic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.
GO:0009863	salicylic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by salicylic acid.
GO:0009864	induced systemic resistance, jasmonic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.
GO:0009865	pollen tube adhesion	biological_process	The process in which the pollen tube adheres to cells of the stigma and style.
GO:0009866	induced systemic resistance, ethylene mediated signaling pathway	biological_process	The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.
GO:0009867	jasmonic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by jasmonic acid.
GO:0009868	jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway	biological_process	The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.
GO:0009871	jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway	biological_process	The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.
GO:0009873	ethylene-activated signaling pathway	biological_process	The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
GO:0009875	pollen-pistil interaction	biological_process	The interaction between a pollen grain and pistil.
GO:0009876	pollen adhesion	biological_process	The process in which pollen deposited on the stigma adheres to cells of the stigma.
GO:0009877	nodulation	biological_process	The formation of nitrogen-fixing root nodules on plant roots.
GO:0009879	determination of radial symmetry	biological_process	The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis.
GO:0009880	embryonic pattern specification	biological_process	The process that results in the patterns of cell differentiation that will arise in an embryo.
GO:0009881	photoreceptor activity	molecular_function	The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
GO:0009882	blue light photoreceptor activity	molecular_function	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.
GO:0009883	red or far-red light photoreceptor activity	molecular_function	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.
GO:0009884	cytokinin receptor activity	molecular_function	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0009885	transmembrane histidine kinase cytokinin receptor activity	molecular_function	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
GO:0009886	post-embryonic animal morphogenesis	biological_process	The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.
GO:0009887	animal organ morphogenesis	biological_process	Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0009888	tissue development	biological_process	The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
GO:0009889	regulation of biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0009890	negative regulation of biosynthetic process	biological_process	Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009891	positive regulation of biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GO:0009892	negative regulation of metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0009893	positive regulation of metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0009894	regulation of catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GO:0009895	negative regulation of catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GO:0009896	positive regulation of catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GO:0009897	external side of plasma membrane	cellular_component	The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
GO:0009898	cytoplasmic side of plasma membrane	cellular_component	The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
GO:0009899	ent-kaurene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.
GO:0009900	dehiscence	biological_process	The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.
GO:0009901	anther dehiscence	biological_process	The dehiscence of an anther to release the pollen grains contained within it.
GO:0009902	chloroplast relocation	biological_process	The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.
GO:0009903	chloroplast avoidance movement	biological_process	The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.
GO:0009904	chloroplast accumulation movement	biological_process	The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.
GO:0009905	ent-copalyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.
GO:0009906	response to photoperiod, blue light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
GO:0009907	response to photoperiod, red light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.
GO:0009908	flower development	biological_process	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
GO:0009909	regulation of flower development	biological_process	Any process that modulates the frequency, rate or extent of flower development.
GO:0009910	negative regulation of flower development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.
GO:0009911	positive regulation of flower development	biological_process	Any process that activates or increases the frequency, rate or extent of flower development.
GO:0009912	auditory receptor cell fate commitment	biological_process	The process in which the cellular identity of auditory hair cells is acquired and determined.
GO:0009913	epidermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
GO:0009914	hormone transport	biological_process	The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0009915	phloem sucrose loading	biological_process	The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
GO:0009916	alternative oxidase activity	molecular_function	Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.
GO:0009917	sterol 5-alpha reductase activity	molecular_function	Catalysis of the removal of a C-5 double bond in the B ring of a sterol.
GO:0009918	sterol delta7 reductase activity	molecular_function	Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.
GO:0009920	cell plate formation involved in plant-type cell wall biogenesis	biological_process	The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.
GO:0009921	auxin efflux carrier complex	cellular_component	The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.
GO:0009922	fatty acid elongase activity	molecular_function	Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer with an additional 2-C unit). This reaction is the condensation step of the endoplasmic reticulum fatty acid elongation cycle.
GO:0009923	fatty acid elongase complex	cellular_component	A tetrameric complex of four different subunits which catalyzes the elongation of a fatty acid chain 2 carbon units at a time in the synthesis of very long chain fatty acids.
GO:0009924	octadecanal decarbonylase activity	molecular_function	Catalysis of the reaction: octadecanal = heptadecane + CO.
GO:0009925	basal plasma membrane	cellular_component	The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
GO:0009926	auxin polar transport	biological_process	The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
GO:0009927	histidine phosphotransfer kinase activity	molecular_function	Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
GO:0009930	longitudinal side of cell surface	cellular_component	The side of the cell parallel to the zygotic axis.
GO:0009931	calcium-dependent protein serine/threonine kinase activity	molecular_function	Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
GO:0009932	cell tip growth	biological_process	Growth that occurs specifically at the tip of a cell.
GO:0009933	meristem structural organization	biological_process	Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
GO:0009934	regulation of meristem structural organization	biological_process	Any process that modulates the frequency, rate or extent of meristem organization.
GO:0009937	regulation of gibberellic acid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.
GO:0009938	negative regulation of gibberellic acid mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.
GO:0009939	positive regulation of gibberellic acid mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.
GO:0009940	amino-terminal vacuolar sorting propeptide binding	molecular_function	Binding to an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.
GO:0009941	chloroplast envelope	cellular_component	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0009942	longitudinal axis specification	biological_process	The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.
GO:0009943	adaxial/abaxial axis specification	biological_process	The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
GO:0009944	polarity specification of adaxial/abaxial axis	biological_process	The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
GO:0009945	radial axis specification	biological_process	The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.
GO:0009946	proximal/distal axis specification	biological_process	The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
GO:0009947	centrolateral axis specification	biological_process	The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.
GO:0009948	anterior/posterior axis specification	biological_process	The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO:0009949	polarity specification of anterior/posterior axis	biological_process	Any process resulting in the establishment of polarity along the anterior/posterior axis.
GO:0009950	dorsal/ventral axis specification	biological_process	The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
GO:0009951	polarity specification of dorsal/ventral axis	biological_process	Any process resulting in the establishment of polarity along the dorsal/ventral axis.
GO:0009952	anterior/posterior pattern specification	biological_process	The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO:0009953	dorsal/ventral pattern formation	biological_process	The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
GO:0009954	proximal/distal pattern formation	biological_process	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
GO:0009955	adaxial/abaxial pattern specification	biological_process	The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
GO:0009956	radial pattern formation	biological_process	The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
GO:0009957	epidermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0009958	positive gravitropism	biological_process	The orientation of plant parts towards gravity.
GO:0009959	negative gravitropism	biological_process	The orientation of plant parts away from gravity.
GO:0009960	endosperm development	biological_process	The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.
GO:0009961	response to 1-aminocyclopropane-1-carboxylic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.
GO:0009962	regulation of flavonoid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
GO:0009963	positive regulation of flavonoid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
GO:0009964	negative regulation of flavonoid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
GO:0009965	leaf morphogenesis	biological_process	The process in which the anatomical structures of the leaf are generated and organized.
GO:0009966	regulation of signal transduction	biological_process	Any process that modulates the frequency, rate or extent of signal transduction.
GO:0009967	positive regulation of signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction.
GO:0009968	negative regulation of signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GO:0009969	xyloglucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
GO:0009970	cellular response to sulfate starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
GO:0009971	anastral spindle assembly involved in male meiosis	biological_process	The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.
GO:0009972	cytidine deamination	biological_process	The removal of amino group in the presence of water.
GO:0009973	adenylyl-sulfate reductase activity	molecular_function	Catalysis of the reaction: A + AMP + 2 H+ + sulfite = adenosine 5'-phosphosulfate + AH2.
GO:0009974	zeinoxanthin epsilon hydroxylase activity	molecular_function	Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.
GO:0009975	cyclase activity	molecular_function	Catalysis of a ring closure reaction.
GO:0009976	tocopherol cyclase activity	molecular_function	Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).
GO:0009977	proton motive force dependent protein transmembrane transporter activity	molecular_function	Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane.
GO:0009978	allene oxide synthase activity	molecular_function	Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.
GO:0009979	16:0 monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.
GO:0009982	pseudouridine synthase activity	molecular_function	Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
GO:0009986	cell surface	cellular_component	The external part of the cell wall and/or plasma membrane.
GO:0009987	cellular process	biological_process	Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0009988	cell-cell recognition	biological_process	Cell recognition between cells. May involve the formation of specialized cell junctions.
GO:0009989	cell-matrix recognition	biological_process	Cell recognition that involves the interaction of the cell with the extracellular matrix.
GO:0009990	contact guidance	biological_process	Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.
GO:0009991	response to extracellular stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
GO:0009992	intracellular water homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of water within a cell.
GO:0009994	oocyte differentiation	biological_process	The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
GO:0009995	soluble molecule recognition	biological_process	The recognition of soluble molecules in the environment.
GO:0009996	negative regulation of cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
GO:0009997	negative regulation of cardioblast cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0009998	negative regulation of retinal cone cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.
GO:0009999	negative regulation of auditory receptor cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.
GO:0010001	glial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.
GO:0010002	cardioblast differentiation	biological_process	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0010004	gastrulation involving germ band extension	biological_process	A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.
GO:0010005	cortical microtubule, transverse to long axis	cellular_component	Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.
GO:0010006	Toc complex	cellular_component	Protein translocon complex at the chloroplast outer membrane.
GO:0010007	magnesium chelatase complex	cellular_component	A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.
GO:0010008	endosome membrane	cellular_component	The lipid bilayer surrounding an endosome.
GO:0010009	cytoplasmic side of endosome membrane	cellular_component	The side (leaflet) of the endosome membrane that faces the cytoplasm.
GO:0010011	auxin binding	molecular_function	Binding to auxin, a plant hormone that regulates aspects of plant growth.
GO:0010012	steroid 22-alpha hydroxylase activity	molecular_function	Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.
GO:0010013	N-1-naphthylphthalamic acid binding	molecular_function	Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.
GO:0010014	meristem initiation	biological_process	Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
GO:0010015	root morphogenesis	biological_process	The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.
GO:0010016	shoot system morphogenesis	biological_process	The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.
GO:0010017	red or far-red light signaling pathway	biological_process	The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0010018	far-red light signaling pathway	biological_process	The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0010019	chloroplast-nucleus signaling pathway	biological_process	The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.
GO:0010020	chloroplast fission	biological_process	The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.
GO:0010021	amylopectin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.
GO:0010022	meristem determinacy	biological_process	The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).
GO:0010023	proanthocyanidin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of proanthocyanidin.
GO:0010024	phytochromobilin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.
GO:0010025	wax biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.
GO:0010026	trichome differentiation	biological_process	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.
GO:0010027	thylakoid membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.
GO:0010028	xanthophyll cycle	biological_process	A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.
GO:0010029	regulation of seed germination	biological_process	Any process that modulates the frequency, rate or extent of seed germination.
GO:0010030	positive regulation of seed germination	biological_process	Any process that activates or increase the rate of seed germination.
GO:0010031	circumnutation	biological_process	The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.
GO:0010032	meiotic chromosome condensation	biological_process	Compaction of chromatin structure prior to meiosis in eukaryotic cells.
GO:0010033	response to organic substance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GO:0010034	response to acetate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.
GO:0010035	response to inorganic substance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
GO:0010036	response to boron-containing substance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.
GO:0010037	response to carbon dioxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
GO:0010038	response to metal ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
GO:0010039	response to iron ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
GO:0010040	response to iron(II) ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
GO:0010041	response to iron(III) ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.
GO:0010042	response to manganese ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
GO:0010043	response to zinc ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
GO:0010044	response to aluminum ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.
GO:0010045	response to nickel cation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.
GO:0010046	response to mycotoxin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
GO:0010047	fruit dehiscence	biological_process	The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
GO:0010048	vernalization response	biological_process	The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.
GO:0010049	acquisition of plant reproductive competence	biological_process	The process in which a plant acquires the ability to respond to a floral inductive signal.
GO:0010050	vegetative phase change	biological_process	Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
GO:0010051	xylem and phloem pattern formation	biological_process	The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
GO:0010052	guard cell differentiation	biological_process	The process in which a guard mother cell acquires the specialized features of a guard cell.
GO:0010053	root epidermal cell differentiation	biological_process	The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.
GO:0010054	trichoblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.
GO:0010055	atrichoblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.
GO:0010056	atrichoblast fate specification	biological_process	The process involved in the specification of an atrichoblast.
GO:0010057	trichoblast fate specification	biological_process	The process involved in the specification of a trichoblast.
GO:0010058	regulation of atrichoblast fate specification	biological_process	Any process that modulates atrichoblast fate specification.
GO:0010059	positive regulation of atrichoblast fate specification	biological_process	Any process that induces or promotes atrichoblast fate specification.
GO:0010060	negative regulation of atrichoblast fate specification	biological_process	Any process that suppresses atrichoblast fate specification.
GO:0010061	regulation of trichoblast fate specification	biological_process	Any process that modulates trichoblast fate specification.
GO:0010062	negative regulation of trichoblast fate specification	biological_process	Any process that suppresses trichoblast fate specification.
GO:0010063	positive regulation of trichoblast fate specification	biological_process	Any process that induces or promotes trichoblast fate specification.
GO:0010064	embryonic shoot morphogenesis	biological_process	The process in which the anatomical structures of embryonic shoot are generated and organized.
GO:0010065	primary meristem tissue development	biological_process	The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.
GO:0010066	ground meristem histogenesis	biological_process	The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.
GO:0010067	procambium histogenesis	biological_process	The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.
GO:0010068	protoderm histogenesis	biological_process	The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.
GO:0010069	zygote asymmetric cytokinesis in embryo sac	biological_process	The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.
GO:0010070	zygote asymmetric cell division	biological_process	The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.
GO:0010071	root meristem specification	biological_process	The specification of a meristem which will give rise to a primary or lateral root.
GO:0010072	primary shoot apical meristem specification	biological_process	The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.
GO:0010073	meristem maintenance	biological_process	Any process involved in maintaining the identity, size and shape of a meristem.
GO:0010074	maintenance of meristem identity	biological_process	The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010075	regulation of meristem growth	biological_process	Any process involved in maintaining the size and shape of a meristem.
GO:0010076	maintenance of floral meristem identity	biological_process	The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010077	maintenance of inflorescence meristem identity	biological_process	The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010078	maintenance of root meristem identity	biological_process	The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010079	maintenance of vegetative meristem identity	biological_process	The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010080	regulation of floral meristem growth	biological_process	Any process involved in maintaining the size and shape of a floral meristem.
GO:0010081	regulation of inflorescence meristem growth	biological_process	Any process involved in maintaining the size and shape of an inflorescence meristem.
GO:0010082	regulation of root meristem growth	biological_process	Any process involved in maintaining the size and shape of a root meristem.
GO:0010083	regulation of vegetative meristem growth	biological_process	Any process involved in maintaining the size and shape of a vegetative meristem.
GO:0010084	specification of animal organ axis polarity	biological_process	The process in which the polarity of an animal organ axis is specified.
GO:0010085	polarity specification of proximal/distal axis	biological_process	Any process resulting in the establishment of polarity along the proximal/distal axis.
GO:0010086	embryonic root morphogenesis	biological_process	The process in which the anatomical structures of the embryonic root are generated and organized.
GO:0010087	phloem or xylem histogenesis	biological_process	The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
GO:0010088	phloem development	biological_process	The formation of the principal food-conducting tissue of a vascular plant.
GO:0010089	xylem development	biological_process	The formation of the principal water-conducting tissue of a vascular plant.
GO:0010090	trichome morphogenesis	biological_process	The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
GO:0010091	trichome branching	biological_process	Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
GO:0010092	specification of animal organ identity	biological_process	The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010093	specification of floral organ identity	biological_process	The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010094	specification of carpel identity	biological_process	The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010095	specification of petal identity	biological_process	The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010096	specification of sepal identity	biological_process	The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010097	specification of stamen identity	biological_process	The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010098	suspensor development	biological_process	The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.
GO:0010099	regulation of photomorphogenesis	biological_process	Any process that modulates the rate or extent of photomorphogenesis.
GO:0010100	negative regulation of photomorphogenesis	biological_process	Any process that stops, reduces or prevents photomorphogenesis.
GO:0010101	post-embryonic root morphogenesis	biological_process	The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.
GO:0010102	lateral root morphogenesis	biological_process	The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
GO:0010103	stomatal complex morphogenesis	biological_process	The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
GO:0010104	regulation of ethylene-activated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction.
GO:0010105	negative regulation of ethylene-activated signaling pathway	biological_process	Any process that stops or prevents ethylene (ethene) signal transduction.
GO:0010106	cellular response to iron ion starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
GO:0010109	regulation of photosynthesis	biological_process	Any process that modulates the frequency, rate or extent of photosynthesis.
GO:0010110	regulation of photosynthesis, dark reaction	biological_process	Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.
GO:0010111	glyoxysome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.
GO:0010112	regulation of systemic acquired resistance	biological_process	Any process that modulates the frequency, rate or extent of systemic acquired resistance.
GO:0010113	negative regulation of systemic acquired resistance	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.
GO:0010114	response to red light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0010115	regulation of abscisic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
GO:0010116	positive regulation of abscisic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
GO:0010117	photoprotection	biological_process	Protection mechanism used by plants and cyanobacteria under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.
GO:0010118	stomatal movement	biological_process	The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).
GO:0010119	regulation of stomatal movement	biological_process	Any process that modulates the frequency, rate or extent of stomatal movement.
GO:0010120	camalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.
GO:0010121	arginine catabolic process to proline via ornithine	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.
GO:0010122	arginine catabolic process to alanine via ornithine	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.
GO:0010124	phenylacetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenylacetate.
GO:0010125	mycothiol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.
GO:0010126	mycothiol metabolic process	biological_process	The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.
GO:0010127	mycothiol-dependent detoxification	biological_process	The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.
GO:0010128	benzoate catabolic process via CoA ligation	biological_process	The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.
GO:0010129	anaerobic cyclohexane-1-carboxylate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.
GO:0010130	anaerobic ethylbenzene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.
GO:0010132	dhurrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.
GO:0010133	proline catabolic process to glutamate	biological_process	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate.
GO:0010134	sulfate assimilation via adenylyl sulfate reduction	biological_process	The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.
GO:0010135	ureide metabolic process	biological_process	The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.
GO:0010136	ureide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.
GO:0010137	ureide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.
GO:0010138	pyrimidine ribonucleotide salvage	biological_process	The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.
GO:0010139	pyrimidine deoxyribonucleotide salvage	biological_process	The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.
GO:0010142	farnesyl diphosphate biosynthetic process, mevalonate pathway	biological_process	The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.
GO:0010143	cutin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.
GO:0010144	pyridoxal phosphate biosynthetic process from pyridoxamine	biological_process	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.
GO:0010145	fructan metabolic process	biological_process	The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.
GO:0010146	fructan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.
GO:0010147	fructan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.
GO:0010148	transpiration	biological_process	Release of water by the plant into the air as water vapor mainly through leaves.
GO:0010150	leaf senescence	biological_process	The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place.
GO:0010151	chloroplast elongation	biological_process	Expansion of the chloroplast that usually precedes division.
GO:0010152	pollen maturation	biological_process	The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.
GO:0010154	fruit development	biological_process	The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
GO:0010155	regulation of proton transport	biological_process	Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010157	response to chlorate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.
GO:0010158	abaxial cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0010159	specification of animal organ position	biological_process	The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ.
GO:0010160	formation of animal organ boundary	biological_process	The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.
GO:0010161	red light signaling pathway	biological_process	The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0010162	seed dormancy process	biological_process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.
GO:0010164	response to cesium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.
GO:0010165	response to X-ray	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
GO:0010166	wax metabolic process	biological_process	The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.
GO:0010167	response to nitrate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
GO:0010168	ER body	cellular_component	A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.
GO:0010169	thioglucosidase complex	cellular_component	A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.
GO:0010170	glucose-1-phosphate adenylyltransferase complex	cellular_component	Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.
GO:0010171	body morphogenesis	biological_process	The process in which the anatomical structures of the soma are generated and organized.
GO:0010172	embryonic body morphogenesis	biological_process	The process in which the anatomical structures of the embryonic soma are generated and organized.
GO:0010174	nucleoside transmembrane transporter activity, against a concentration gradient	molecular_function	Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.
GO:0010176	homogentisate phytyltransferase activity	molecular_function	Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.
GO:0010177	2-(2'-methylthio)ethylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.
GO:0010178	IAA-amino acid conjugate hydrolase activity	molecular_function	Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.
GO:0010179	IAA-Ala conjugate hydrolase activity	molecular_function	Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.
GO:0010180	thioglucosidase binding	molecular_function	Binding to a thioglucosidase enzyme.
GO:0010181	FMN binding	molecular_function	Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0010182	sugar mediated signaling pathway	biological_process	The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
GO:0010183	pollen tube guidance	biological_process	The process in which the growth of pollen tube is directed towards the female gametophyte.
GO:0010184	cytokinin transport	biological_process	The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010185	regulation of cellular defense response	biological_process	Any process that modulates the frequency, rate or extent of cellular defense response.
GO:0010186	positive regulation of cellular defense response	biological_process	Any process that activates or increases the frequency, rate or extent of cellular defense response.
GO:0010187	negative regulation of seed germination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.
GO:0010188	response to microbial phytotoxin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.
GO:0010189	vitamin E biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
GO:0010190	cytochrome b6f complex assembly	biological_process	Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.
GO:0010191	mucilage metabolic process	biological_process	The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.
GO:0010192	mucilage biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.
GO:0010193	response to ozone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
GO:0010196	nonphotochemical quenching	biological_process	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.
GO:0010197	polar nucleus fusion	biological_process	The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
GO:0010198	synergid death	biological_process	Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
GO:0010199	organ boundary specification between lateral organs and the meristem	biological_process	The process in which boundaries between lateral organs and the meristem is established and maintained.
GO:0010200	response to chitin	biological_process	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
GO:0010201	response to continuous far red light stimulus by the high-irradiance response system	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.
GO:0010202	response to low fluence red light stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.
GO:0010203	response to very low fluence red light stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.
GO:0010205	photoinhibition	biological_process	The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.
GO:0010206	photosystem II repair	biological_process	Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.
GO:0010207	photosystem II assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.
GO:0010208	pollen wall assembly	biological_process	The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.
GO:0010209	vacuolar sorting signal binding	molecular_function	Binding to a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.
GO:0010210	IAA-Phe conjugate hydrolase activity	molecular_function	Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.
GO:0010211	IAA-Leu conjugate hydrolase activity	molecular_function	Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.
GO:0010212	response to ionizing radiation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
GO:0010213	non-photoreactive DNA repair	biological_process	A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.
GO:0010214	seed coat development	biological_process	The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
GO:0010215	cellulose microfibril organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.
GO:0010218	response to far red light	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0010219	regulation of vernalization response	biological_process	Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
GO:0010220	positive regulation of vernalization response	biological_process	Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
GO:0010221	negative regulation of vernalization response	biological_process	Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
GO:0010222	stem vascular tissue pattern formation	biological_process	Vascular tissue pattern formation as it occurs in the stem of vascular plants.
GO:0010223	secondary shoot formation	biological_process	The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.
GO:0010224	response to UV-B	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
GO:0010225	response to UV-C	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
GO:0010226	response to lithium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
GO:0010227	floral organ abscission	biological_process	The controlled shedding of floral organs.
GO:0010228	vegetative to reproductive phase transition of meristem	biological_process	The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
GO:0010229	inflorescence development	biological_process	The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.
GO:0010230	alternative respiration	biological_process	Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.
GO:0010231	maintenance of seed dormancy	biological_process	Any process that maintains a seed in a dormant state.
GO:0010232	vascular transport	biological_process	The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.
GO:0010233	phloem transport	biological_process	The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues.
GO:0010234	anther wall tapetum cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0010235	guard mother cell cytokinesis	biological_process	The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.
GO:0010236	plastoquinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.
GO:0010238	response to proline	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.
GO:0010239	chloroplast mRNA processing	biological_process	Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.
GO:0010240	plastid pyruvate dehydrogenase complex	cellular_component	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.
GO:0010241	ent-kaurene oxidation to kaurenoic acid	biological_process	The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.
GO:0010242	oxygen evolving activity	molecular_function	Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
GO:0010243	response to organonitrogen compound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
GO:0010244	response to low fluence blue light stimulus by blue low-fluence system	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.
GO:0010245	radial microtubular system formation	biological_process	Formation of radial microtubular systems during male meiotic cytokinesis in plants.
GO:0010246	rhamnogalacturonan I biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.
GO:0010247	detection of phosphate ion	biological_process	The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	biological_process	The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.
GO:0010249	auxin conjugate metabolic process	biological_process	The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.
GO:0010250	S-methylmethionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.
GO:0010253	UDP-rhamnose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.
GO:0010254	nectary development	biological_process	The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.
GO:0010255	glucose mediated signaling pathway	biological_process	The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.
GO:0010256	endomembrane system organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
GO:0010257	NADH dehydrogenase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.
GO:0010258	NADH dehydrogenase complex (plastoquinone) assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.
GO:0010262	somatic embryogenesis	biological_process	Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.
GO:0010263	tricyclic triterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.
GO:0010264	myo-inositol hexakisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
GO:0010265	SCF complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.
GO:0010266	response to vitamin B1	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.
GO:0010267	ta-siRNA processing	biological_process	A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs.
GO:0010268	brassinosteroid homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.
GO:0010269	response to selenium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.
GO:0010270	photosystem II oxygen evolving complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.
GO:0010271	regulation of chlorophyll catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.
GO:0010272	response to silver ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
GO:0010273	detoxification of copper ion	biological_process	Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
GO:0010274	hydrotropism	biological_process	Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.
GO:0010275	NAD(P)H dehydrogenase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.
GO:0010276	phytol kinase activity	molecular_function	Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.
GO:0010277	chlorophyllide a oxygenase [overall] activity	molecular_function	Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
GO:0010278	chloroplast outer membrane translocon	cellular_component	The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.
GO:0010279	indole-3-acetic acid amido synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.
GO:0010280	UDP-L-rhamnose synthase activity	molecular_function	Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.
GO:0010282	senescence-associated vacuole	cellular_component	A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.
GO:0010283	pinoresinol reductase activity	molecular_function	Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.
GO:0010284	lariciresinol reductase activity	molecular_function	Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.
GO:0010285	L,L-diaminopimelate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H+.
GO:0010286	heat acclimation	biological_process	Any process that increases heat tolerance of an organism in response to high temperatures.
GO:0010287	plastoglobule	cellular_component	A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.
GO:0010288	response to lead ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
GO:0010289	homogalacturonan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
GO:0010290	chlorophyll catabolite transmembrane transporter activity	molecular_function	Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other.
GO:0010291	carotene beta-ring hydroxylase activity	molecular_function	Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.
GO:0010292	GTP:GDP antiporter activity	molecular_function	Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).
GO:0010293	abscisic aldehyde oxidase activity	molecular_function	Catalysis of the reaction: (+)-abscisic aldehyde + H2O + O2 = abscisate + H2O2 + H+.
GO:0010294	abscisic acid glucosyltransferase activity	molecular_function	Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.
GO:0010295	(+)-abscisic acid 8'-hydroxylase activity	molecular_function	Catalysis of the reaction: (+)-abscisate + H+ + NADPH + O2 = (+)-8'-hydroxyabscisate + H2O + NADP+.
GO:0010296	prenylcysteine methylesterase activity	molecular_function	Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.
GO:0010297	heteropolysaccharide binding	molecular_function	Binding to a heteropolysaccharide, a glycan composed of more than one type of monosaccharide residue.
GO:0010298	dihydrocamalexic acid decarboxylase activity	molecular_function	Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.
GO:0010299	detoxification of cobalt ion	biological_process	Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.
GO:0010301	xanthoxin dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + xanthoxin = (+)-abscisic aldehyde + H+ + NADH.
GO:0010303	limit dextrinase activity	molecular_function	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.
GO:0010304	PSII associated light-harvesting complex II catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.
GO:0010305	leaf vascular tissue pattern formation	biological_process	Vascular tissue pattern formation as it occurs in the leaf of vascular plants.
GO:0010306	rhamnogalacturonan II biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.
GO:0010307	acetylglutamate kinase regulator activity	molecular_function	Binds to and modulates the activity of acetylglutamate kinase.
GO:0010308	acireductone dioxygenase (Ni2+-requiring) activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + CO + formate.
GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-methylthio-2-oxobutanoate + formate + H+.
GO:0010310	regulation of hydrogen peroxide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
GO:0010311	lateral root formation	biological_process	The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.
GO:0010312	detoxification of zinc ion	biological_process	Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.
GO:0010313	phytochrome binding	molecular_function	Binding to a phytochrome.
GO:0010314	phosphatidylinositol-5-phosphate binding	molecular_function	Binding to phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.
GO:0010315	auxin export across the plasma membrane	biological_process	The directed movement of auxins from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0010316	pyrophosphate-dependent phosphofructokinase complex	cellular_component	Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.
GO:0010317	pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex	cellular_component	Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.
GO:0010318	pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex	cellular_component	Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.
GO:0010319	stromule	cellular_component	Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.
GO:0010321	regulation of vegetative phase change	biological_process	Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
GO:0010322	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).
GO:0010323	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).
GO:0010324	membrane invagination	biological_process	The infolding of a membrane.
GO:0010325	raffinose family oligosaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).
GO:0010326	methionine-oxo-acid transaminase activity	molecular_function	Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid.
GO:0010327	acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.
GO:0010328	auxin influx transmembrane transporter activity	molecular_function	Enables the transfer of auxin, from one side of a membrane to the other, into a cell.
GO:0010329	auxin efflux transmembrane transporter activity	molecular_function	Enables the transfer of auxin, from one side of a membrane to the other, out of a cell.
GO:0010330	cellulose synthase complex	cellular_component	A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.
GO:0010331	gibberellin binding	molecular_function	Binding to a gibberellin, a plant hormone that regulates aspects of plant growth.
GO:0010332	response to gamma radiation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
GO:0010333	terpene synthase activity	molecular_function	Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.
GO:0010334	sesquiterpene synthase activity	molecular_function	Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.
GO:0010335	response to non-ionic osmotic stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
GO:0010336	gibberellic acid homeostasis	biological_process	Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.
GO:0010337	regulation of salicylic acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.
GO:0010338	leaf formation	biological_process	The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.
GO:0010339	external side of cell wall	cellular_component	The side of the cell wall that is opposite to the side that faces the cell and its contents.
GO:0010340	carboxyl-O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.
GO:0010341	gibberellin carboxyl-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.
GO:0010342	endosperm cellularization	biological_process	The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.
GO:0010343	singlet oxygen-mediated programmed cell death	biological_process	Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.
GO:0010344	seed oilbody biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.
GO:0010345	suberin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.
GO:0010346	shoot axis formation	biological_process	The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.
GO:0010347	L-galactose-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.
GO:0010348	lithium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).
GO:0010349	L-galactose dehydrogenase activity	molecular_function	Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.
GO:0010350	cellular response to magnesium starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.
GO:0010351	lithium ion transport	biological_process	The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010352	lithium ion export across the plasma membrane	biological_process	The directed movement of lithium ion out of a cell or organelle.
GO:0010353	response to trehalose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.
GO:0010354	homogentisate prenyltransferase activity	molecular_function	Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.
GO:0010355	homogentisate farnesyltransferase activity	molecular_function	Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.
GO:0010356	homogentisate geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.
GO:0010357	homogentisate solanesyltransferase activity	molecular_function	Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.
GO:0010358	leaf shaping	biological_process	The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.
GO:0010359	regulation of anion channel activity	biological_process	Any process that modulates the frequency, rate or extent of anion channel activity.
GO:0010360	negative regulation of anion channel activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
GO:0010361	regulation of anion channel activity by blue light	biological_process	Any process in which blue light modulates the frequency, rate or extent of anion channel activity.
GO:0010362	negative regulation of anion channel activity by blue light	biological_process	Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
GO:0010363	regulation of plant-type hypersensitive response	biological_process	Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.
GO:0010364	regulation of ethylene biosynthetic process	biological_process	Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.
GO:0010365	positive regulation of ethylene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.
GO:0010366	negative regulation of ethylene biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.
GO:0010367	extracellular isoamylase complex	cellular_component	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.
GO:0010368	chloroplast isoamylase complex	cellular_component	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.
GO:0010369	chromocenter	cellular_component	A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure.
GO:0010370	perinucleolar chromocenter	cellular_component	A chromocenter adjacent to the nucleolus.
GO:0010371	regulation of gibberellin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
GO:0010372	positive regulation of gibberellin biosynthetic process	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
GO:0010373	negative regulation of gibberellin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
GO:0010374	stomatal complex development	biological_process	The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
GO:0010375	stomatal complex patterning	biological_process	The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
GO:0010376	stomatal complex formation	biological_process	The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
GO:0010377	guard cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.
GO:0010378	temperature compensation of the circadian clock	biological_process	The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.
GO:0010379	phaseic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).
GO:0010380	regulation of chlorophyll biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
GO:0010381	peroxisome-chloroplast membrane tethering	biological_process	The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
GO:0010383	cell wall polysaccharide metabolic process	biological_process	The chemical reactions and pathways involving cell wall polysaccharides.
GO:0010384	cell wall proteoglycan metabolic process	biological_process	The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.
GO:0010385	double-stranded methylated DNA binding	molecular_function	Binding to double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
GO:0010387	COP9 signalosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.
GO:0010389	regulation of G2/M transition of mitotic cell cycle	biological_process	Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
GO:0010390	histone monoubiquitination	biological_process	The modification of histones by addition of a single ubiquitin group.
GO:0010391	glucomannan metabolic process	biological_process	The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.
GO:0010392	galactoglucomannan metabolic process	biological_process	The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.
GO:0010393	galacturonan metabolic process	biological_process	The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.
GO:0010394	homogalacturonan metabolic process	biological_process	The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
GO:0010395	rhamnogalacturonan I metabolic process	biological_process	The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.
GO:0010396	rhamnogalacturonan II metabolic process	biological_process	The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.
GO:0010397	apiogalacturonan metabolic process	biological_process	The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.
GO:0010398	xylogalacturonan metabolic process	biological_process	The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.
GO:0010399	rhamnogalacturonan I backbone metabolic process	biological_process	The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.
GO:0010400	rhamnogalacturonan I side chain metabolic process	biological_process	The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.
GO:0010401	pectic galactan metabolic process	biological_process	The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.
GO:0010402	pectic arabinan metabolic process	biological_process	The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.
GO:0010403	pectic arabinogalactan I metabolic process	biological_process	The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.
GO:0010404	cell wall hydroxyproline-rich glycoprotein metabolic process	biological_process	The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.
GO:0010405	arabinogalactan protein metabolic process	biological_process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.
GO:0010406	classical arabinogalactan protein metabolic process	biological_process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.
GO:0010407	non-classical arabinogalactan protein metabolic process	biological_process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.
GO:0010408	fasciclin-like arabinogalactan protein metabolic process	biological_process	The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.
GO:0010409	extensin metabolic process	biological_process	The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.
GO:0010410	hemicellulose metabolic process	biological_process	The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.
GO:0010411	xyloglucan metabolic process	biological_process	The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
GO:0010412	mannan metabolic process	biological_process	The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.
GO:0010413	glucuronoxylan metabolic process	biological_process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.
GO:0010414	glucuronoarabinoxylan metabolic process	biological_process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.
GO:0010415	unsubstituted mannan metabolic process	biological_process	The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units.
GO:0010416	arabinoxylan-containing compound metabolic process	biological_process	The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units.
GO:0010417	glucuronoxylan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.
GO:0010418	rhamnogalacturonan II backbone metabolic process	biological_process	The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues.
GO:0010419	rhamnogalacturonan II side chain metabolic process	biological_process	The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.
GO:0010420	3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.
GO:0010421	hydrogen peroxide-mediated programmed cell death	biological_process	Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.
GO:0010422	regulation of brassinosteroid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.
GO:0010423	negative regulation of brassinosteroid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.
GO:0010424	DNA methylation on cytosine within a CG sequence	biological_process	The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.
GO:0010425	DNA methylation on cytosine within a CNG sequence	biological_process	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide.
GO:0010426	DNA methylation on cytosine within a CHH sequence	biological_process	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.
GO:0010427	abscisic acid binding	molecular_function	Binding to abscisic acid, a plant hormone that regulates aspects of plant growth.
GO:0010428	methyl-CpNpG binding	molecular_function	Binding to a methylated cytosine/unspecified/guanine trinucleotide.
GO:0010429	methyl-CpNpN binding	molecular_function	Binding to a methylated cytosine/unspecified/unspecified trinucleotide.
GO:0010430	fatty acid omega-oxidation	biological_process	A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
GO:0010431	seed maturation	biological_process	A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.
GO:0010432	bract development	biological_process	The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
GO:0010433	bract morphogenesis	biological_process	The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
GO:0010434	bract formation	biological_process	The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
GO:0010435	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0.
GO:0010436	carotenoid dioxygenase activity	molecular_function	Catalysis of the oxidative cleavage of carotenoids.
GO:0010437	9,10 (9', 10')-carotenoid-cleaving dioxygenase activity	molecular_function	Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.
GO:0010438	cellular response to sulfur starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.
GO:0010439	regulation of glucosinolate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0010440	stomatal lineage progression	biological_process	The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.
GO:0010441	guard cell development	biological_process	The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.
GO:0010442	guard cell morphogenesis	biological_process	Generation and organization of the polarized cell that is capable of turgor driven movement.
GO:0010443	meristemoid mother cell division	biological_process	The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.
GO:0010444	guard mother cell differentiation	biological_process	The process in which a meristemoid acquires the specialized features of a guard mother cell.
GO:0010445	nuclear dicing body	cellular_component	A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.
GO:0010446	response to alkaline pH	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0010447	response to acidic pH	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0010448	vegetative meristem growth	biological_process	The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.
GO:0010449	root meristem growth	biological_process	The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.
GO:0010450	inflorescence meristem growth	biological_process	The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.
GO:0010451	floral meristem growth	biological_process	The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.
GO:0010452	histone H3-K36 methylation	biological_process	The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.
GO:0010453	regulation of cell fate commitment	biological_process	Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
GO:0010454	negative regulation of cell fate commitment	biological_process	Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
GO:0010455	positive regulation of cell fate commitment	biological_process	Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
GO:0010456	cell proliferation in dorsal spinal cord	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.
GO:0010457	centriole-centriole cohesion	biological_process	The cell cycle process in which the two centrioles within a centrosome remain tightly paired.
GO:0010458	exit from mitosis	biological_process	The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
GO:0010459	negative regulation of heart rate	biological_process	Any process that stops, prevents or reduces the frequency or rate of heart contraction.
GO:0010460	positive regulation of heart rate	biological_process	Any process that activates or increases the frequency or rate of heart contraction.
GO:0010461	light-activated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic ion by a channel that opens in response to a light stimulus.
GO:0010462	regulation of light-activated voltage-gated calcium channel activity	biological_process	Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.
GO:0010463	mesenchymal cell proliferation	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0010464	regulation of mesenchymal cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0010465	nerve growth factor receptor activity	molecular_function	Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.
GO:0010466	negative regulation of peptidase activity	biological_process	Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
GO:0010467	gene expression	biological_process	The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.
GO:0010468	regulation of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0010469	regulation of signaling receptor activity	biological_process	Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
GO:0010470	regulation of gastrulation	biological_process	Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.
GO:0010471	GDP-galactose:mannose-1-phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + beta-L-galactose-1-phosphate.
GO:0010472	GDP-galactose:glucose-1-phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: GDP-beta-L-galactose + alpha-D-glucose 1-phosphate = beta-L-galactose-1-phosphate + GDP-alpha-D-glucose.
GO:0010473	GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.
GO:0010476	gibberellin mediated signaling pathway	biological_process	The series of molecular signals generated as a consequence of gibberellin stimulus.
GO:0010477	response to sulfur dioxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.
GO:0010478	chlororespiration	biological_process	A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.
GO:0010479	stele development	biological_process	The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.
GO:0010480	microsporocyte differentiation	biological_process	The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.
GO:0010481	epidermal cell division	biological_process	Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.
GO:0010482	regulation of epidermal cell division	biological_process	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.
GO:0010483	pollen tube reception	biological_process	Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.
GO:0010484	histone H3 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.
GO:0010485	histone H4 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
GO:0010486	manganese:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).
GO:0010487	thermospermine synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.
GO:0010488	UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.
GO:0010489	UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity	molecular_function	Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.
GO:0010490	UDP-4-keto-rhamnose-4-keto-reductase activity	molecular_function	Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.
GO:0010491	UTP:arabinose-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.
GO:0010492	maintenance of shoot apical meristem identity	biological_process	The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
GO:0010493	Lewis a epitope biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.
GO:0010494	cytoplasmic stress granule	cellular_component	A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
GO:0010495	siRNA-mediated long-distance post-transcriptional gene silencing	biological_process	An siRNA-mediated posttranscriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs, and in which the silencing signal originates in one tissue and occurs in a different tissue.
GO:0010496	intercellular transport	biological_process	The movement of substances between cells.
GO:0010497	plasmodesmata-mediated intercellular transport	biological_process	The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
GO:0010498	proteasomal protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
GO:0010499	proteasomal ubiquitin-independent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.
GO:0010500	transmitting tissue development	biological_process	The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.
GO:0010501	RNA secondary structure unwinding	biological_process	The process in which a secondary structure of RNA are broken or 'melted'.
GO:0010506	regulation of autophagy	biological_process	Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GO:0010507	negative regulation of autophagy	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GO:0010508	positive regulation of autophagy	biological_process	Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GO:0010509	intracellular polyamine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of polyamine within a cell.
GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
GO:0010511	regulation of phosphatidylinositol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
GO:0010513	positive regulation of phosphatidylinositol biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
GO:0010514	induction of conjugation with cellular fusion	biological_process	The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.
GO:0010515	negative regulation of induction of conjugation with cellular fusion	biological_process	Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.
GO:0010516	negative regulation of cellular response to nitrogen starvation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.
GO:0010517	regulation of phospholipase activity	biological_process	Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
GO:0010518	positive regulation of phospholipase activity	biological_process	Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
GO:0010519	negative regulation of phospholipase activity	biological_process	Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
GO:0010520	regulation of reciprocal meiotic recombination	biological_process	Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010521	telomerase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of telomerase.
GO:0010522	regulation of calcium ion transport into cytosol	biological_process	Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
GO:0010523	negative regulation of calcium ion transport into cytosol	biological_process	Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
GO:0010524	positive regulation of calcium ion transport into cytosol	biological_process	Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
GO:0010526	retrotransposon silencing	biological_process	Any process that decreases the frequency, rate or extent of retrotransposition. Retrotransposons are a subset of transposable elements that use an RNA intermediate and reverse transcribe themselves into the genome.
GO:0010533	regulation of activation of Janus kinase activity	biological_process	Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
GO:0010536	positive regulation of activation of Janus kinase activity	biological_process	Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
GO:0010540	basipetal auxin transport	biological_process	The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.
GO:0010541	acropetal auxin transport	biological_process	The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.
GO:0010542	nitrate efflux transmembrane transporter activity	molecular_function	Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.
GO:0010543	regulation of platelet activation	biological_process	Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GO:0010544	negative regulation of platelet activation	biological_process	Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GO:0010547	thylakoid membrane disassembly	biological_process	The controlled breakdown of the thylakoid membrane in the context of a normal process.
GO:0010548	regulation of thylakoid membrane disassembly	biological_process	Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.
GO:0010549	regulation of membrane disassembly	biological_process	Any process that modulates the frequency, rate or extent of membrane disassembly.
GO:0010550	regulation of PSII associated light-harvesting complex II catabolic process	biological_process	Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.
GO:0010555	response to mannitol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.
GO:0010556	regulation of macromolecule biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010557	positive regulation of macromolecule biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010558	negative regulation of macromolecule biosynthetic process	biological_process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010559	regulation of glycoprotein biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0010560	positive regulation of glycoprotein biosynthetic process	biological_process	Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0010561	negative regulation of glycoprotein biosynthetic process	biological_process	Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
GO:0010562	positive regulation of phosphorus metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GO:0010563	negative regulation of phosphorus metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GO:0010564	regulation of cell cycle process	biological_process	Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GO:0010565	regulation of cellular ketone metabolic process	biological_process	Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GO:0010566	regulation of ketone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.
GO:0010567	regulation of ketone catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.
GO:0010568	regulation of budding cell apical bud growth	biological_process	Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.
GO:0010569	regulation of double-strand break repair via homologous recombination	biological_process	Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
GO:0010570	regulation of filamentous growth	biological_process	Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
GO:0010571	positive regulation of nuclear cell cycle DNA replication	biological_process	Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
GO:0010572	positive regulation of platelet activation	biological_process	Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
GO:0010573	vascular endothelial growth factor production	biological_process	The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0010574	regulation of vascular endothelial growth factor production	biological_process	Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.
GO:0010575	positive regulation of vascular endothelial growth factor production	biological_process	Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
GO:0010578	regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway.
GO:0010581	regulation of starch biosynthetic process	biological_process	An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.
GO:0010582	floral meristem determinacy	biological_process	The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).
GO:0010583	response to cyclopentenone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.
GO:0010584	pollen exine formation	biological_process	The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.
GO:0010585	glutamine secretion	biological_process	The controlled release of glutamine by a cell.
GO:0010586	miRNA metabolic process	biological_process	The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
GO:0010587	miRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
GO:0010588	cotyledon vascular tissue pattern formation	biological_process	Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.
GO:0010589	leaf proximal/distal pattern formation	biological_process	The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.
GO:0010590	regulation of septum digestion after cytokinesis	biological_process	Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
GO:0010591	regulation of lamellipodium assembly	biological_process	Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
GO:0010592	positive regulation of lamellipodium assembly	biological_process	Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
GO:0010593	negative regulation of lamellipodium assembly	biological_process	Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
GO:0010594	regulation of endothelial cell migration	biological_process	Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
GO:0010595	positive regulation of endothelial cell migration	biological_process	Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
GO:0010596	negative regulation of endothelial cell migration	biological_process	Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
GO:0010597	green leaf volatile biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.
GO:0010598	NAD(P)H dehydrogenase complex (plastoquinone)	cellular_component	Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.
GO:0010599	lsiRNA processing	biological_process	A process leading to the generation of a functional long small interfering RNA (lsiRNA). lsiRNAs are class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.
GO:0010600	regulation of auxin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
GO:0010601	positive regulation of auxin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
GO:0010602	regulation of 1-aminocyclopropane-1-carboxylate metabolic process	biological_process	Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
GO:0010603	regulation of cytoplasmic mRNA processing body assembly	biological_process	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
GO:0010604	positive regulation of macromolecule metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010605	negative regulation of macromolecule metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	biological_process	Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly	biological_process	Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
GO:0010608	post-transcriptional regulation of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
GO:0010609	mRNA localization resulting in post-transcriptional regulation of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.
GO:0010610	regulation of mRNA stability involved in response to stress	biological_process	Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.
GO:0010611	regulation of cardiac muscle hypertrophy	biological_process	Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
GO:0010612	regulation of cardiac muscle adaptation	biological_process	Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
GO:0010613	positive regulation of cardiac muscle hypertrophy	biological_process	Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
GO:0010614	negative regulation of cardiac muscle hypertrophy	biological_process	Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
GO:0010615	positive regulation of cardiac muscle adaptation	biological_process	Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
GO:0010616	negative regulation of cardiac muscle adaptation	biological_process	Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
GO:0010617	circadian regulation of calcium ion oscillation	biological_process	Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.
GO:0010618	aerenchyma formation	biological_process	The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.
GO:0010619	adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	biological_process	An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by glucose binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
GO:0010620	negative regulation of transcription by transcription factor catabolism	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0010621	negative regulation of transcription by transcription factor localization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.
GO:0010622	specification of ovule identity	biological_process	The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0010623	programmed cell death involved in cell development	biological_process	The activation of endogenous cellular processes that result in the death of a cell as part of its development.
GO:0010624	regulation of Schwann cell proliferation	biological_process	Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
GO:0010625	positive regulation of Schwann cell proliferation	biological_process	Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
GO:0010626	negative regulation of Schwann cell proliferation	biological_process	Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
GO:0010628	positive regulation of gene expression	biological_process	Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0010629	negative regulation of gene expression	biological_process	Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0010630	regulation of transcription, start site selection	biological_process	Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.
GO:0010631	epithelial cell migration	biological_process	The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
GO:0010632	regulation of epithelial cell migration	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell migration.
GO:0010633	negative regulation of epithelial cell migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.
GO:0010634	positive regulation of epithelial cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
GO:0010635	regulation of mitochondrial fusion	biological_process	Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GO:0010636	positive regulation of mitochondrial fusion	biological_process	Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GO:0010637	negative regulation of mitochondrial fusion	biological_process	Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GO:0010638	positive regulation of organelle organization	biological_process	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GO:0010639	negative regulation of organelle organization	biological_process	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	biological_process	Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
GO:0010643	cell communication by chemical coupling	biological_process	The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
GO:0010644	cell communication by electrical coupling	biological_process	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0010645	regulation of cell communication by chemical coupling	biological_process	Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
GO:0010646	regulation of cell communication	biological_process	Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0010647	positive regulation of cell communication	biological_process	Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0010648	negative regulation of cell communication	biological_process	Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0010649	regulation of cell communication by electrical coupling	biological_process	Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0010650	positive regulation of cell communication by electrical coupling	biological_process	Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0010651	negative regulation of cell communication by electrical coupling	biological_process	Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0010652	positive regulation of cell communication by chemical coupling	biological_process	Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
GO:0010653	negative regulation of cell communication by chemical coupling	biological_process	Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
GO:0010654	apical cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.
GO:0010656	negative regulation of muscle cell apoptotic process	biological_process	Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
GO:0010657	muscle cell apoptotic process	biological_process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.
GO:0010658	striated muscle cell apoptotic process	biological_process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.
GO:0010659	cardiac muscle cell apoptotic process	biological_process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
GO:0010660	regulation of muscle cell apoptotic process	biological_process	Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
GO:0010661	positive regulation of muscle cell apoptotic process	biological_process	Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
GO:0010662	regulation of striated muscle cell apoptotic process	biological_process	Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
GO:0010663	positive regulation of striated muscle cell apoptotic process	biological_process	Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
GO:0010664	negative regulation of striated muscle cell apoptotic process	biological_process	Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
GO:0010665	regulation of cardiac muscle cell apoptotic process	biological_process	Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	biological_process	Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	biological_process	Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
GO:0010668	ectodermal cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0010669	epithelial structure maintenance	biological_process	A tissue homeostatic process required for the maintenance of epithelial structure.
GO:0010672	regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	biological_process	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GO:0010673	positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GO:0010674	negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	biological_process	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
GO:0010683	tricyclic triterpenoid metabolic process	biological_process	The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
GO:0010684	tricyclic triterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
GO:0010685	tetracyclic triterpenoid metabolic process	biological_process	The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
GO:0010686	tetracyclic triterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
GO:0010688	negative regulation of ribosomal protein gene transcription by RNA polymerase II	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.
GO:0010689	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.
GO:0010690	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.
GO:0010691	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
GO:0010692	regulation of alkaline phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
GO:0010693	negative regulation of alkaline phosphatase activity	biological_process	Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
GO:0010694	positive regulation of alkaline phosphatase activity	biological_process	Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
GO:0010695	regulation of mitotic spindle pole body separation	biological_process	Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
GO:0010696	positive regulation of mitotic spindle pole body separation	biological_process	Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
GO:0010697	negative regulation of mitotic spindle pole body separation	biological_process	Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
GO:0010698	acetyltransferase activator activity	molecular_function	Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.
GO:0010700	negative regulation of norepinephrine secretion	biological_process	Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.
GO:0010701	positive regulation of norepinephrine secretion	biological_process	Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.
GO:0010704	meiotic DNA double-strand break processing involved in meiotic gene conversion	biological_process	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.
GO:0010705	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination	biological_process	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.
GO:0010706	ganglioside biosynthetic process via lactosylceramide	biological_process	The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
GO:0010707	globoside biosynthetic process via lactosylceramide	biological_process	The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
GO:0010709	heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing	biological_process	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.
GO:0010710	regulation of collagen catabolic process	biological_process	Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
GO:0010711	negative regulation of collagen catabolic process	biological_process	Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
GO:0010712	regulation of collagen metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0010713	negative regulation of collagen metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0010714	positive regulation of collagen metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0010715	regulation of extracellular matrix disassembly	biological_process	Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GO:0010716	negative regulation of extracellular matrix disassembly	biological_process	Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GO:0010717	regulation of epithelial to mesenchymal transition	biological_process	Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0010718	positive regulation of epithelial to mesenchymal transition	biological_process	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0010719	negative regulation of epithelial to mesenchymal transition	biological_process	Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0010720	positive regulation of cell development	biological_process	Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0010721	negative regulation of cell development	biological_process	Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0010722	regulation of ferrochelatase activity	biological_process	Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.
GO:0010723	positive regulation of transcription from RNA polymerase II promoter in response to iron	biological_process	Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.
GO:0010724	regulation of definitive erythrocyte differentiation	biological_process	Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
GO:0010725	regulation of primitive erythrocyte differentiation	biological_process	Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.
GO:0010726	positive regulation of hydrogen peroxide metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
GO:0010727	negative regulation of hydrogen peroxide metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
GO:0010728	regulation of hydrogen peroxide biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
GO:0010729	positive regulation of hydrogen peroxide biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
GO:0010730	negative regulation of hydrogen peroxide biosynthetic process	biological_process	Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
GO:0010731	protein glutathionylation	biological_process	The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
GO:0010732	regulation of protein glutathionylation	biological_process	Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
GO:0010733	positive regulation of protein glutathionylation	biological_process	Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
GO:0010734	negative regulation of protein glutathionylation	biological_process	Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
GO:0010736	serum response element binding	molecular_function	Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
GO:0010737	protein kinase A signaling	biological_process	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
GO:0010738	regulation of protein kinase A signaling	biological_process	Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
GO:0010739	positive regulation of protein kinase A signaling	biological_process	Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
GO:0010742	macrophage derived foam cell differentiation	biological_process	The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0010743	regulation of macrophage derived foam cell differentiation	biological_process	Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0010744	positive regulation of macrophage derived foam cell differentiation	biological_process	Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0010745	negative regulation of macrophage derived foam cell differentiation	biological_process	Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0010746	regulation of long-chain fatty acid import across plasma membrane	biological_process	Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO:0010747	positive regulation of long-chain fatty acid import across plasma membrane	biological_process	Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO:0010748	negative regulation of long-chain fatty acid import across plasma membrane	biological_process	Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.
GO:0010749	regulation of nitric oxide mediated signal transduction	biological_process	Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
GO:0010750	positive regulation of nitric oxide mediated signal transduction	biological_process	Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
GO:0010751	negative regulation of nitric oxide mediated signal transduction	biological_process	Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
GO:0010752	regulation of cGMP-mediated signaling	biological_process	Any process that modulates the rate, frequency or extent of cGMP-mediated signaling.
GO:0010753	positive regulation of cGMP-mediated signaling	biological_process	Any process that increases the rate, frequency or extent of cGMP-mediated signaling.
GO:0010754	negative regulation of cGMP-mediated signaling	biological_process	Any process that decreases the rate, frequency or extent of cGMP-mediated signaling.
GO:0010755	regulation of plasminogen activation	biological_process	Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
GO:0010756	positive regulation of plasminogen activation	biological_process	Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
GO:0010757	negative regulation of plasminogen activation	biological_process	Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
GO:0010758	regulation of macrophage chemotaxis	biological_process	Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
GO:0010759	positive regulation of macrophage chemotaxis	biological_process	Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
GO:0010760	negative regulation of macrophage chemotaxis	biological_process	Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
GO:0010761	fibroblast migration	biological_process	Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0010762	regulation of fibroblast migration	biological_process	Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
GO:0010763	positive regulation of fibroblast migration	biological_process	Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
GO:0010764	negative regulation of fibroblast migration	biological_process	Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
GO:0010765	positive regulation of sodium ion transport	biological_process	Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010766	negative regulation of sodium ion transport	biological_process	Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010770	positive regulation of cell morphogenesis	biological_process	Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GO:0010771	negative regulation of cell morphogenesis	biological_process	Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GO:0010772	meiotic DNA recombinase assembly involved in reciprocal meiotic recombination	biological_process	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010773	meiotic DNA recombinase assembly involved in meiotic gene conversion	biological_process	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
GO:0010774	meiotic strand invasion involved in reciprocal meiotic recombination	biological_process	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010775	meiotic strand invasion involved in meiotic gene conversion	biological_process	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.
GO:0010776	meiotic mismatch repair involved in meiotic gene conversion	biological_process	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
GO:0010777	meiotic mismatch repair involved in reciprocal meiotic recombination	biological_process	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010778	meiotic DNA repair synthesis involved in reciprocal meiotic recombination	biological_process	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010779	meiotic DNA repair synthesis involved in meiotic gene conversion	biological_process	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
GO:0010780	meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	biological_process	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010781	meiotic DNA double-strand break formation involved in meiotic gene conversion	biological_process	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
GO:0010782	proboscis morphogenesis, labial disc-derived	biological_process	The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.
GO:0010783	proboscis morphogenesis, eye-antennal disc-derived	biological_process	The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.
GO:0010784	proboscis morphogenesis, clypeo-labral disc-derived	biological_process	The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.
GO:0010785	clathrin coating of Golgi vesicle, plasma membrane to endosome targeting	biological_process	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.
GO:0010786	clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting	biological_process	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.
GO:0010787	COPI coating of Golgi vesicle, inter-Golgi cisterna	biological_process	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.
GO:0010788	COPI coating of Golgi vesicle, cis-Golgi to rough ER	biological_process	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.
GO:0010789	meiotic sister chromatid cohesion involved in meiosis I	biological_process	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
GO:0010790	meiotic sister chromatid cohesion involved in meiosis II	biological_process	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.
GO:0010791	DNA double-strand break processing involved in repair via synthesis-dependent strand annealing	biological_process	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	biological_process	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.
GO:0010793	regulation of mRNA export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.
GO:0010794	regulation of dolichol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
GO:0010795	regulation of ubiquinone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
GO:0010796	regulation of multivesicular body size	biological_process	Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.
GO:0010797	regulation of multivesicular body size involved in endosome transport	biological_process	Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.
GO:0010798	regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism	biological_process	Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.
GO:0010799	regulation of peptidyl-threonine phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	biological_process	Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	biological_process	Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	biological_process	Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	biological_process	Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
GO:0010807	regulation of synaptic vesicle priming	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
GO:0010808	positive regulation of synaptic vesicle priming	biological_process	Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
GO:0010809	negative regulation of synaptic vesicle priming	biological_process	Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
GO:0010810	regulation of cell-substrate adhesion	biological_process	Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
GO:0010811	positive regulation of cell-substrate adhesion	biological_process	Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
GO:0010812	negative regulation of cell-substrate adhesion	biological_process	Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
GO:0010813	neuropeptide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.
GO:0010814	substance P catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.
GO:0010815	bradykinin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.
GO:0010816	calcitonin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.
GO:0010817	regulation of hormone levels	biological_process	Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.
GO:0010818	T cell chemotaxis	biological_process	The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
GO:0010819	regulation of T cell chemotaxis	biological_process	Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
GO:0010820	positive regulation of T cell chemotaxis	biological_process	Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
GO:0010821	regulation of mitochondrion organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GO:0010822	positive regulation of mitochondrion organization	biological_process	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GO:0010823	negative regulation of mitochondrion organization	biological_process	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GO:0010824	regulation of centrosome duplication	biological_process	Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
GO:0010825	positive regulation of centrosome duplication	biological_process	Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
GO:0010826	negative regulation of centrosome duplication	biological_process	Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
GO:0010827	regulation of glucose transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010828	positive regulation of glucose transmembrane transport	biological_process	Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010829	negative regulation of glucose transmembrane transport	biological_process	Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010830	regulation of myotube differentiation	biological_process	Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0010831	positive regulation of myotube differentiation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0010832	negative regulation of myotube differentiation	biological_process	Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0010833	telomere maintenance via telomere lengthening	biological_process	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.
GO:0010835	regulation of protein ADP-ribosylation	biological_process	Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
GO:0010836	negative regulation of protein ADP-ribosylation	biological_process	Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
GO:0010837	regulation of keratinocyte proliferation	biological_process	Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
GO:0010838	positive regulation of keratinocyte proliferation	biological_process	Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
GO:0010839	negative regulation of keratinocyte proliferation	biological_process	Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
GO:0010840	regulation of circadian sleep/wake cycle, wakefulness	biological_process	Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	biological_process	Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
GO:0010842	retina layer formation	biological_process	The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
GO:0010844	recombination hotspot binding	molecular_function	Binding to a genomic region which promotes recombination.
GO:0010845	positive regulation of reciprocal meiotic recombination	biological_process	Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010846	activation of reciprocal meiotic recombination	biological_process	Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism	biological_process	Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
GO:0010850	regulation of blood pressure by chemoreceptor signaling pathway	biological_process	A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
GO:0010851	cyclase regulator activity	molecular_function	Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.
GO:0010852	cyclase inhibitor activity	molecular_function	Binds to and decreases the activity of an enzyme that catalyzes a ring closure reaction.
GO:0010853	cyclase activator activity	molecular_function	Binds to and increases the activity of an enzyme that catalyzes a ring closure reaction.
GO:0010854	adenylate cyclase regulator activity	molecular_function	Binds to and modulates the activity of adenylate cyclase.
GO:0010855	adenylate cyclase inhibitor activity	molecular_function	Binds to and decreases the activity of adenylate cyclase.
GO:0010856	adenylate cyclase activator activity	molecular_function	Binds to and increases the activity of adenylate cyclase.
GO:0010857	calcium-dependent protein kinase activity	molecular_function	Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0010858	calcium-dependent protein kinase regulator activity	molecular_function	Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.
GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.
GO:0010863	positive regulation of phospholipase C activity	biological_process	Any process that increases the rate of phospholipase C activity.
GO:0010864	positive regulation of protein histidine kinase activity	biological_process	Any process that increases the frequency, rate or extent of protein histidine kinase activity.
GO:0010865	stipule development	biological_process	The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.
GO:0010866	regulation of triglyceride biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
GO:0010867	positive regulation of triglyceride biosynthetic process	biological_process	Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
GO:0010868	negative regulation of triglyceride biosynthetic process	biological_process	Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
GO:0010874	regulation of cholesterol efflux	biological_process	Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
GO:0010875	positive regulation of cholesterol efflux	biological_process	Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
GO:0010876	lipid localization	biological_process	Any process in which a lipid is transported to, or maintained in, a specific location.
GO:0010877	lipid transport involved in lipid storage	biological_process	The directed movement of lipids into cells that is part of their accumulation and maintenance.
GO:0010878	cholesterol storage	biological_process	The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0010879	cholesterol transport involved in cholesterol storage	biological_process	The directed movement of cholesterol into cells that is part of their accumulation and maintenance.
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological_process	Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.
GO:0010883	regulation of lipid storage	biological_process	Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
GO:0010884	positive regulation of lipid storage	biological_process	Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
GO:0010885	regulation of cholesterol storage	biological_process	Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0010886	positive regulation of cholesterol storage	biological_process	Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0010887	negative regulation of cholesterol storage	biological_process	Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0010888	negative regulation of lipid storage	biological_process	Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
GO:0010889	regulation of sequestering of triglyceride	biological_process	Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
GO:0010890	positive regulation of sequestering of triglyceride	biological_process	Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
GO:0010891	negative regulation of sequestering of triglyceride	biological_process	Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
GO:0010892	positive regulation of mitochondrial translation in response to stress	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.
GO:0010893	positive regulation of steroid biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:0010894	negative regulation of steroid biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:0010895	negative regulation of ergosterol biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
GO:0010896	regulation of triglyceride catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
GO:0010897	negative regulation of triglyceride catabolic process	biological_process	Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
GO:0010898	positive regulation of triglyceride catabolic process	biological_process	Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
GO:0010899	regulation of phosphatidylcholine catabolic process	biological_process	Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0010900	negative regulation of phosphatidylcholine catabolic process	biological_process	Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	biological_process	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	biological_process	Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	biological_process	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0010904	regulation of UDP-glucose catabolic process	biological_process	Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
GO:0010905	negative regulation of UDP-glucose catabolic process	biological_process	Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
GO:0010906	regulation of glucose metabolic process	biological_process	Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
GO:0010907	positive regulation of glucose metabolic process	biological_process	Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
GO:0010910	positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity	biological_process	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.
GO:0010911	regulation of isomerase activity	biological_process	Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0010912	positive regulation of isomerase activity	biological_process	Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0010913	regulation of sterigmatocystin biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
GO:0010914	positive regulation of sterigmatocystin biosynthetic process	biological_process	Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
GO:0010915	regulation of very-low-density lipoprotein particle clearance	biological_process	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	biological_process	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010917	negative regulation of mitochondrial membrane potential	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0010918	positive regulation of mitochondrial membrane potential	biological_process	Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0010919	regulation of inositol phosphate biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0010920	negative regulation of inositol phosphate biosynthetic process	biological_process	Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0010921	regulation of phosphatase activity	biological_process	Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0010922	positive regulation of phosphatase activity	biological_process	Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0010923	negative regulation of phosphatase activity	biological_process	Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0010924	regulation of inositol-polyphosphate 5-phosphatase activity	biological_process	Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity	biological_process	Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
GO:0010927	cellular component assembly involved in morphogenesis	biological_process	The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
GO:0010928	regulation of auxin mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
GO:0010929	positive regulation of auxin mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
GO:0010930	negative regulation of auxin mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
GO:0010931	macrophage tolerance induction	biological_process	A process involving any mechanism for tolerance induction in macrophages.
GO:0010932	regulation of macrophage tolerance induction	biological_process	Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.
GO:0010933	positive regulation of macrophage tolerance induction	biological_process	Any process that increases the frequency, rate, or extent of B cell tolerance induction.
GO:0010934	macrophage cytokine production	biological_process	The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0010935	regulation of macrophage cytokine production	biological_process	Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0010936	negative regulation of macrophage cytokine production	biological_process	Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0010937	regulation of cytoplasmic microtubule depolymerization	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.
GO:0010938	cytoplasmic microtubule depolymerization	biological_process	The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.
GO:0010943	NADPH pyrophosphatase activity	molecular_function	Catalysis of the reaction: NADPH + H2O = NMNH + ADP.
GO:0010944	negative regulation of transcription by competitive promoter binding	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.
GO:0010945	CoA pyrophosphatase activity	molecular_function	Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine.
GO:0010946	regulation of meiotic joint molecule formation	biological_process	Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
GO:0010947	negative regulation of meiotic joint molecule formation	biological_process	Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
GO:0010948	negative regulation of cell cycle process	biological_process	Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GO:0010949	negative regulation of intestinal phytosterol absorption	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.
GO:0010950	positive regulation of endopeptidase activity	biological_process	Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GO:0010951	negative regulation of endopeptidase activity	biological_process	Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GO:0010952	positive regulation of peptidase activity	biological_process	Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GO:0010954	positive regulation of protein processing	biological_process	Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.
GO:0010955	negative regulation of protein processing	biological_process	Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	biological_process	Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
GO:0010957	negative regulation of vitamin D biosynthetic process	biological_process	Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0010958	regulation of amino acid import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of amino acid import into a cell.
GO:0010959	regulation of metal ion transport	biological_process	Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010960	magnesium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
GO:0010961	intracellular magnesium ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell.
GO:0010962	regulation of glucan biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
GO:0010964	regulation of regulatory ncRNA-mediated heterochromatin formation	biological_process	Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.
GO:0010965	regulation of mitotic sister chromatid separation	biological_process	Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.
GO:0010966	regulation of phosphate transport	biological_process	Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0010967	regulation of polyamine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
GO:0010968	regulation of microtubule nucleation	biological_process	Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
GO:0010969	regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	biological_process	Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
GO:0010970	transport along microtubule	biological_process	The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	biological_process	Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	biological_process	Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
GO:0010973	positive regulation of division septum assembly	biological_process	Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0010974	negative regulation of division septum assembly	biological_process	Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0010975	regulation of neuron projection development	biological_process	Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GO:0010976	positive regulation of neuron projection development	biological_process	Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GO:0010977	negative regulation of neuron projection development	biological_process	Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GO:0010979	regulation of vitamin D 24-hydroxylase activity	biological_process	Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	biological_process	Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
GO:0010981	regulation of cell wall macromolecule metabolic process	biological_process	Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0010982	regulation of high-density lipoprotein particle clearance	biological_process	Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010983	positive regulation of high-density lipoprotein particle clearance	biological_process	Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010984	regulation of lipoprotein particle clearance	biological_process	Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010985	negative regulation of lipoprotein particle clearance	biological_process	Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010986	positive regulation of lipoprotein particle clearance	biological_process	Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010987	negative regulation of high-density lipoprotein particle clearance	biological_process	Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010988	regulation of low-density lipoprotein particle clearance	biological_process	Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010989	negative regulation of low-density lipoprotein particle clearance	biological_process	Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0010992	ubiquitin recycling	biological_process	Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.
GO:0010994	free ubiquitin chain polymerization	biological_process	The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.
GO:0010995	free ubiquitin chain depolymerization	biological_process	The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.
GO:0010996	response to auditory stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
GO:0010997	anaphase-promoting complex binding	molecular_function	Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	biological_process	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.
GO:0011000	replication fork arrest at mating type locus	biological_process	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.
GO:0012501	programmed cell death	biological_process	A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0012502	induction of programmed cell death	biological_process	A process which directly activates any of the steps required for programmed cell death.
GO:0012505	endomembrane system	cellular_component	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GO:0012506	vesicle membrane	cellular_component	The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
GO:0012507	ER to Golgi transport vesicle membrane	cellular_component	The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
GO:0012508	Golgi to ER transport vesicle membrane	cellular_component	The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.
GO:0012509	inter-Golgi transport vesicle membrane	cellular_component	The lipid bilayer surrounding a vesicle transporting substances within the Golgi.
GO:0012510	trans-Golgi network transport vesicle membrane	cellular_component	The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
GO:0012511	monolayer-surrounded lipid storage body	cellular_component	A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
GO:0014001	sclerenchyma cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.
GO:0014002	astrocyte development	biological_process	The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
GO:0014003	oligodendrocyte development	biological_process	The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
GO:0014004	microglia differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
GO:0014005	microglia development	biological_process	The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0014006	regulation of microglia differentiation	biological_process	Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
GO:0014007	negative regulation of microglia differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
GO:0014008	positive regulation of microglia differentiation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
GO:0014009	glial cell proliferation	biological_process	The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
GO:0014010	Schwann cell proliferation	biological_process	The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
GO:0014011	Schwann cell proliferation involved in axon regeneration	biological_process	The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.
GO:0014012	peripheral nervous system axon regeneration	biological_process	The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.
GO:0014013	regulation of gliogenesis	biological_process	Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.
GO:0014014	negative regulation of gliogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.
GO:0014015	positive regulation of gliogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.
GO:0014016	neuroblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
GO:0014017	neuroblast fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.
GO:0014018	neuroblast fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0014019	neuroblast development	biological_process	The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.
GO:0014020	primary neural tube formation	biological_process	The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
GO:0014021	secondary neural tube formation	biological_process	The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.
GO:0014022	neural plate elongation	biological_process	The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.
GO:0014023	neural rod formation	biological_process	The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.
GO:0014025	neural keel formation	biological_process	The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.
GO:0014028	notochord formation	biological_process	The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.
GO:0014029	neural crest formation	biological_process	The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
GO:0014030	mesenchymal cell fate commitment	biological_process	The process in which a cell becomes committed to become a mesenchymal cell.
GO:0014031	mesenchymal cell development	biological_process	The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0014032	neural crest cell development	biological_process	The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0014033	neural crest cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
GO:0014034	neural crest cell fate commitment	biological_process	The process in which a cell becomes committed to become a neural crest cell.
GO:0014035	neural crest cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0014036	neural crest cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0014037	Schwann cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
GO:0014038	regulation of Schwann cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of Schwann cell differentiation.
GO:0014039	negative regulation of Schwann cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.
GO:0014040	positive regulation of Schwann cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.
GO:0014041	regulation of neuron maturation	biological_process	Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.
GO:0014042	positive regulation of neuron maturation	biological_process	Any process that activates or increases the frequency, rate or extent of neuron maturation.
GO:0014043	negative regulation of neuron maturation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
GO:0014044	Schwann cell development	biological_process	The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
GO:0014045	establishment of endothelial blood-brain barrier	biological_process	Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
GO:0014046	dopamine secretion	biological_process	The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.
GO:0014047	glutamate secretion	biological_process	The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.
GO:0014048	regulation of glutamate secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of glutamate.
GO:0014049	positive regulation of glutamate secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
GO:0014050	negative regulation of glutamate secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
GO:0014051	gamma-aminobutyric acid secretion	biological_process	The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
GO:0014052	regulation of gamma-aminobutyric acid secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
GO:0014055	acetylcholine secretion, neurotransmission	biological_process	The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).
GO:0014056	regulation of acetylcholine secretion, neurotransmission	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
GO:0014057	positive regulation of acetylcholine secretion, neurotransmission	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
GO:0014058	negative regulation of acetylcholine secretion, neurotransmission	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.
GO:0014059	regulation of dopamine secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
GO:0014060	regulation of epinephrine secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.
GO:0014061	regulation of norepinephrine secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.
GO:0014062	regulation of serotonin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of serotonin.
GO:0014063	negative regulation of serotonin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.
GO:0014064	positive regulation of serotonin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.
GO:0014069	postsynaptic density	cellular_component	An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GO:0014070	response to organic cyclic compound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
GO:0014071	response to cycloalkane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.
GO:0014072	response to isoquinoline alkaloid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
GO:0014073	response to tropane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.
GO:0014074	response to purine-containing compound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
GO:0014075	response to amine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
GO:0014076	response to fluoxetine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
GO:0014701	junctional sarcoplasmic reticulum membrane	cellular_component	The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.
GO:0014702	free sarcoplasmic reticulum membrane	cellular_component	The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.
GO:0014703	oscillatory muscle contraction	biological_process	A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.
GO:0014704	intercalated disc	cellular_component	A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
GO:0014705	C zone	cellular_component	A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.
GO:0014706	striated muscle tissue development	biological_process	The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.
GO:0014707	branchiomeric skeletal muscle development	biological_process	The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.
GO:0014708	regulation of somitomeric trunk muscle development	biological_process	Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.
GO:0014709	positive regulation of somitomeric trunk muscle development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
GO:0014710	negative regulation of somitomeric trunk muscle development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
GO:0014711	regulation of branchiomeric skeletal muscle development	biological_process	Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
GO:0014712	positive regulation of branchiomeric skeletal muscle development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
GO:0014713	negative regulation of branchiomeric skeletal muscle development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
GO:0014714	myoblast fate commitment in head	biological_process	The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014715	myoblast fate commitment in trunk	biological_process	The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014716	skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration	biological_process	Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt.
GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration	biological_process	Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
GO:0014719	skeletal muscle satellite cell activation	biological_process	The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
GO:0014720	tonic skeletal muscle contraction	biological_process	A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.
GO:0014721	twitch skeletal muscle contraction	biological_process	A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.
GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.
GO:0014723	regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.
GO:0014724	regulation of twitch skeletal muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.
GO:0014725	regulation of extraocular skeletal muscle development	biological_process	Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
GO:0014726	negative regulation of extraocular skeletal muscle development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
GO:0014727	positive regulation of extraocular skeletal muscle development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
GO:0014728	regulation of the force of skeletal muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.
GO:0014729	regulation of the velocity of shortening of skeletal muscle modulating contraction	biological_process	Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.
GO:0014730	skeletal muscle regeneration at neuromuscular junction	biological_process	The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.
GO:0014731	spectrin-associated cytoskeleton	cellular_component	The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
GO:0014732	skeletal muscle atrophy	biological_process	A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
GO:0014733	regulation of skeletal muscle adaptation	biological_process	Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
GO:0014734	skeletal muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.
GO:0014735	regulation of muscle atrophy	biological_process	Any process that modulates the frequency, rate or extent of muscle atrophy.
GO:0014736	negative regulation of muscle atrophy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.
GO:0014737	positive regulation of muscle atrophy	biological_process	Any process that activates or increases the frequency, rate or extent of muscle atrophy.
GO:0014738	regulation of muscle hyperplasia	biological_process	Any process that modulates the frequency, rate or extent of muscle hyperplasia.
GO:0014739	positive regulation of muscle hyperplasia	biological_process	Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.
GO:0014740	negative regulation of muscle hyperplasia	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.
GO:0014741	negative regulation of muscle hypertrophy	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.
GO:0014742	positive regulation of muscle hypertrophy	biological_process	Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.
GO:0014743	regulation of muscle hypertrophy	biological_process	Any process that modulates the frequency, rate or extent of muscle hypertrophy.
GO:0014744	positive regulation of muscle adaptation	biological_process	Any process that activates or increases the frequency, rate or extent of muscle adaptation.
GO:0014745	negative regulation of muscle adaptation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.
GO:0014746	regulation of tonic skeletal muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.
GO:0014747	positive regulation of tonic skeletal muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.
GO:0014748	negative regulation of tonic skeletal muscle contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.
GO:0014801	longitudinal sarcoplasmic reticulum	cellular_component	The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.
GO:0014802	terminal cisterna	cellular_component	The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.
GO:0014803	longitudinal sarcoplasmic reticulum lumen	cellular_component	The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.
GO:0014804	terminal cisterna lumen	cellular_component	The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.
GO:0014805	smooth muscle adaptation	biological_process	Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
GO:0014806	smooth muscle hyperplasia	biological_process	A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.
GO:0014807	regulation of somitogenesis	biological_process	Any process that modulates the frequency, rate or extent of somitogenesis.
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	biological_process	The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
GO:0014810	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
GO:0014811	negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
GO:0014812	muscle cell migration	biological_process	The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.
GO:0014813	skeletal muscle satellite cell commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.
GO:0014814	axon regeneration at neuromuscular junction	biological_process	The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.
GO:0014816	skeletal muscle satellite cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.
GO:0014817	skeletal muscle satellite cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0014818	skeletal muscle satellite cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0014819	regulation of skeletal muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction.
GO:0014820	tonic smooth muscle contraction	biological_process	A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.
GO:0014821	phasic smooth muscle contraction	biological_process	A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.
GO:0014822	detection of wounding	biological_process	The series of events by which an injury stimulus is received and converted into a molecular signal.
GO:0014823	response to activity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
GO:0014824	artery smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.
GO:0014825	stomach fundus smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.
GO:0014826	vein smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.
GO:0014827	intestine smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.
GO:0014828	distal stomach smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.
GO:0014829	vascular associated smooth muscle contraction	biological_process	A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.
GO:0014830	arteriole smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.
GO:0014831	gastro-intestinal system smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).
GO:0014832	urinary bladder smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.
GO:0014833	skeletal muscle satellite stem cell asymmetric division	biological_process	The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.
GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	biological_process	Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	biological_process	The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014836	myoblast fate commitment involved in skeletal muscle regeneration	biological_process	The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014837	myoblast fate determination involved in skeletal muscle regeneration	biological_process	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014838	myoblast fate specification involved in skeletal muscle regeneration	biological_process	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014839	myoblast migration involved in skeletal muscle regeneration	biological_process	The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014841	skeletal muscle satellite cell proliferation	biological_process	The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
GO:0014842	regulation of skeletal muscle satellite cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.
GO:0014843	growth factor dependent regulation of skeletal muscle satellite cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
GO:0014844	myoblast proliferation involved in skeletal muscle regeneration	biological_process	The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014845	stomach body smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.
GO:0014846	esophagus smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.
GO:0014847	proximal stomach smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
GO:0014848	urinary tract smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
GO:0014849	ureter smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.
GO:0014850	response to muscle activity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
GO:0014852	regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	biological_process	Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
GO:0014854	response to inactivity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.
GO:0014855	striated muscle cell proliferation	biological_process	The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
GO:0014856	skeletal muscle cell proliferation	biological_process	The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.
GO:0014857	regulation of skeletal muscle cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.
GO:0014858	positive regulation of skeletal muscle cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.
GO:0014859	negative regulation of skeletal muscle cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.
GO:0014860	neurotransmitter secretion involved in regulation of skeletal muscle contraction	biological_process	The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
GO:0014861	regulation of skeletal muscle contraction via regulation of action potential	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.
GO:0014862	regulation of skeletal muscle contraction by chemo-mechanical energy conversion	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.
GO:0014863	detection of inactivity	biological_process	The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.
GO:0014864	detection of muscle activity	biological_process	The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.
GO:0014865	detection of activity	biological_process	The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.
GO:0014866	skeletal myofibril assembly	biological_process	The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.
GO:0014868	cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction	biological_process	A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.
GO:0014869	detection of muscle inactivity	biological_process	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.
GO:0014870	response to muscle inactivity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.
GO:0014871	cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction	biological_process	The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.
GO:0014872	myoblast division	biological_process	The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.
GO:0014874	response to stimulus involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.
GO:0014875	detection of muscle activity involved in regulation of muscle adaptation	biological_process	The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
GO:0014876	response to injury involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.
GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.
GO:0014879	detection of electrical stimulus involved in regulation of muscle adaptation	biological_process	The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
GO:0014880	regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
GO:0014881	regulation of myofibril size	biological_process	Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
GO:0014882	regulation of myofibril number	biological_process	Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
GO:0014883	transition between fast and slow fiber	biological_process	The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.
GO:0014884	detection of muscle inactivity involved in regulation of muscle adaptation	biological_process	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
GO:0014885	detection of injury involved in regulation of muscle adaptation	biological_process	The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
GO:0014886	transition between slow and fast fiber	biological_process	The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.
GO:0014887	cardiac muscle adaptation	biological_process	The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
GO:0014888	striated muscle adaptation	biological_process	Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
GO:0014889	muscle atrophy	biological_process	A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
GO:0014890	smooth muscle atrophy	biological_process	A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
GO:0014891	striated muscle atrophy	biological_process	A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
GO:0014893	response to rest involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.
GO:0014894	response to denervation involved in regulation of muscle adaptation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.
GO:0014895	smooth muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.
GO:0014896	muscle hypertrophy	biological_process	The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
GO:0014897	striated muscle hypertrophy	biological_process	The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.
GO:0014898	cardiac muscle hypertrophy in response to stress	biological_process	The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.
GO:0014899	cardiac muscle atrophy	biological_process	A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.
GO:0014900	muscle hyperplasia	biological_process	A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.
GO:0014901	satellite cell activation involved in skeletal muscle regeneration	biological_process	The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
GO:0014902	myotube differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0014904	myotube cell development	biological_process	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0014905	myoblast fusion involved in skeletal muscle regeneration	biological_process	A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014906	myotube cell development involved in skeletal muscle regeneration	biological_process	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
GO:0014909	smooth muscle cell migration	biological_process	The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.
GO:0014910	regulation of smooth muscle cell migration	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle cell migration.
GO:0014911	positive regulation of smooth muscle cell migration	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
GO:0014912	negative regulation of smooth muscle cell migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
GO:0014914	myoblast maturation involved in muscle regeneration	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0014915	regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction	biological_process	Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
GO:0014916	regulation of lung blood pressure	biological_process	The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.
GO:0015009	corrin metabolic process	biological_process	The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
GO:0015010	tetrahydrocorphin metabolic process	biological_process	The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.
GO:0015011	nickel-tetrapyrrole coenzyme metabolic process	biological_process	The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.
GO:0015012	heparan sulfate proteoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
GO:0015013	heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide	biological_process	The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	biological_process	The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.
GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.
GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.
GO:0015019	heparan-alpha-glucosaminide N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.
GO:0015020	glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
GO:0015021	heparin-sulfate lyase activity	molecular_function	Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.
GO:0015024	glucuronate-2-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.
GO:0015026	coreceptor activity	molecular_function	Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
GO:0015030	Cajal body	cellular_component	A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
GO:0015031	protein transport	biological_process	The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015035	protein-disulfide reductase activity	molecular_function	Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
GO:0015036	disulfide oxidoreductase activity	molecular_function	Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
GO:0015038	glutathione disulfide oxidoreductase activity	molecular_function	Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
GO:0015039	NADPH-adrenodoxin reductase activity	molecular_function	Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.
GO:0015042	trypanothione-disulfide reductase (NADP) activity	molecular_function	Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
GO:0015043	leghemoglobin reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin.
GO:0015044	rubredoxin-NAD+ reductase activity	molecular_function	Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.
GO:0015045	rubredoxin-NAD(P)+ reductase activity	molecular_function	Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.
GO:0015046	rubredoxin-NADP+ reductase activity	molecular_function	Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.
GO:0015047	NADPH-cytochrome-c2 reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.
GO:0015048	phthalate dioxygenase reductase activity	molecular_function	Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.
GO:0015049	methane monooxygenase activity	molecular_function	Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.
GO:0015050	methane monooxygenase complex	cellular_component	A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.
GO:0015052	beta3-adrenergic receptor activity	molecular_function	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.
GO:0015054	gastrin receptor activity	molecular_function	Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.
GO:0015055	secretin receptor activity	molecular_function	Combining with secretin to initiate a change in cell activity.
GO:0015056	corticotrophin-releasing factor receptor activity	molecular_function	Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.
GO:0015057	thrombin-activated receptor activity	molecular_function	A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.
GO:0015066	alpha-amylase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of alpha-amylase.
GO:0015067	amidinotransferase activity	molecular_function	Catalysis of the reversible transfer of an amidino group to an acceptor.
GO:0015068	glycine amidinotransferase activity	molecular_function	Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.
GO:0015069	scyllo-inosamine-4-phosphate amidinotransferase activity	molecular_function	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.
GO:0015074	DNA integration	biological_process	The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
GO:0015075	monoatomic ion transmembrane transporter activity	molecular_function	Enables the transfer of an ion from one side of a membrane to the other.
GO:0015078	proton transmembrane transporter activity	molecular_function	Enables the transfer of a proton from one side of a membrane to the other.
GO:0015079	potassium ion transmembrane transporter activity	molecular_function	Enables the transfer of potassium ions (K+) from one side of a membrane to the other.
GO:0015080	silver ion transmembrane transporter activity	molecular_function	Enables the transfer of silver (Ag) ions from one side of a membrane to the other.
GO:0015081	sodium ion transmembrane transporter activity	molecular_function	Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.
GO:0015083	aluminum ion transmembrane transporter activity	molecular_function	Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.
GO:0015085	calcium ion transmembrane transporter activity	molecular_function	Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.
GO:0015086	cadmium ion transmembrane transporter activity	molecular_function	Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
GO:0015087	cobalt ion transmembrane transporter activity	molecular_function	Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.
GO:0015089	high-affinity copper ion transmembrane transporter activity	molecular_function	Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015090	low-affinity ferric iron ion transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0015091	ferric iron transmembrane transporter activity	molecular_function	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.
GO:0015092	high-affinity ferric iron transmembrane transporter activity	molecular_function	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015093	ferrous iron transmembrane transporter activity	molecular_function	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
GO:0015094	lead ion transmembrane transporter activity	molecular_function	Enables the transfer of lead (Pb) ions from one side of a membrane to the other.
GO:0015095	magnesium ion transmembrane transporter activity	molecular_function	Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.
GO:0015097	mercury ion transmembrane transporter activity	molecular_function	Enables the transfer of mercury (Hg) ions from one side of a membrane to the other.
GO:0015098	molybdate ion transmembrane transporter activity	molecular_function	Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.
GO:0015099	nickel cation transmembrane transporter activity	molecular_function	Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.
GO:0015100	vanadium ion transmembrane transporter activity	molecular_function	Enables the transfer of vanadium (V) ions from one side of a membrane to the other.
GO:0015101	organic cation transmembrane transporter activity	molecular_function	Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
GO:0015103	inorganic anion transmembrane transporter activity	molecular_function	Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
GO:0015104	antimonite transmembrane transporter activity	molecular_function	Enables the transfer of antimonite from one side of a membrane to the other.
GO:0015105	arsenite transmembrane transporter activity	molecular_function	Enables the transfer of arsenite from one side of a membrane to the other.
GO:0015106	bicarbonate transmembrane transporter activity	molecular_function	Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
GO:0015107	chlorate transmembrane transporter activity	molecular_function	Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.
GO:0015108	chloride transmembrane transporter activity	molecular_function	Enables the transfer of chloride ions from one side of a membrane to the other.
GO:0015109	chromate transmembrane transporter activity	molecular_function	Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.
GO:0015110	cyanate transmembrane transporter activity	molecular_function	Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.
GO:0015111	iodide transmembrane transporter activity	molecular_function	Enables the transfer of iodide ions from one side of a membrane to the other.
GO:0015112	nitrate transmembrane transporter activity	molecular_function	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.
GO:0015113	nitrite transmembrane transporter activity	molecular_function	Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.
GO:0015114	phosphate ion transmembrane transporter activity	molecular_function	Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.
GO:0015115	silicate transmembrane transporter activity	molecular_function	Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
GO:0015116	sulfate transmembrane transporter activity	molecular_function	Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
GO:0015117	thiosulfate transmembrane transporter activity	molecular_function	Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.
GO:0015119	hexose phosphate transmembrane transporter activity	molecular_function	Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.
GO:0015120	phosphoglycerate transmembrane transporter activity	molecular_function	Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.
GO:0015121	phosphoenolpyruvate:phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).
GO:0015123	acetate transmembrane transporter activity	molecular_function	Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.
GO:0015124	allantoate transmembrane transporter activity	molecular_function	Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.
GO:0015125	bile acid transmembrane transporter activity	molecular_function	Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
GO:0015126	canalicular bile acid transmembrane transporter activity	molecular_function	The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
GO:0015127	bilirubin transmembrane transporter activity	molecular_function	Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
GO:0015128	gluconate transmembrane transporter activity	molecular_function	Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.
GO:0015129	lactate transmembrane transporter activity	molecular_function	Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
GO:0015130	mevalonate transmembrane transporter activity	molecular_function	Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.
GO:0015131	oxaloacetate transmembrane transporter activity	molecular_function	Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other.
GO:0015132	prostaglandin transmembrane transporter activity	molecular_function	Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
GO:0015133	uronic acid transmembrane transporter activity	molecular_function	Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.
GO:0015134	hexuronate transmembrane transporter activity	molecular_function	Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.
GO:0015135	glucuronate transmembrane transporter activity	molecular_function	Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
GO:0015136	sialic acid transmembrane transporter activity	molecular_function	Enables the transfer of sialic acid from one side of a membrane to the other.
GO:0015137	citrate transmembrane transporter activity	molecular_function	Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.
GO:0015138	fumarate transmembrane transporter activity	molecular_function	Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
GO:0015139	alpha-ketoglutarate transmembrane transporter activity	molecular_function	Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
GO:0015140	malate transmembrane transporter activity	molecular_function	Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
GO:0015141	succinate transmembrane transporter activity	molecular_function	Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.
GO:0015142	tricarboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.
GO:0015143	urate transmembrane transporter activity	molecular_function	Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
GO:0015144	carbohydrate transmembrane transporter activity	molecular_function	Enables the transfer of carbohydrate from one side of a membrane to the other.
GO:0015145	monosaccharide transmembrane transporter activity	molecular_function	Enables the transfer of a monosaccharide from one side of a membrane to the other.
GO:0015146	pentose transmembrane transporter activity	molecular_function	Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.
GO:0015147	L-arabinose transmembrane transporter activity	molecular_function	Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.
GO:0015148	D-xylose transmembrane transporter activity	molecular_function	Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
GO:0015149	hexose transmembrane transporter activity	molecular_function	Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.
GO:0015150	fucose transmembrane transporter activity	molecular_function	Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
GO:0015151	alpha-glucoside transmembrane transporter activity	molecular_function	Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.
GO:0015152	glucose-6-phosphate transmembrane transporter activity	molecular_function	Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
GO:0015153	rhamnose transmembrane transporter activity	molecular_function	Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
GO:0015154	disaccharide transmembrane transporter activity	molecular_function	Enables the transfer of disaccharide from one side of a membrane to the other.
GO:0015155	lactose transmembrane transporter activity	molecular_function	Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
GO:0015156	melibiose transmembrane transporter activity	molecular_function	Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.
GO:0015157	oligosaccharide transmembrane transporter activity	molecular_function	Enables the transfer of oligosaccharide from one side of a membrane to the other.
GO:0015158	raffinose transmembrane transporter activity	molecular_function	Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
GO:0015159	polysaccharide transmembrane transporter activity	molecular_function	Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0015160	beta-glucan transmembrane transporter activity	molecular_function	Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
GO:0015161	lipid III floppase activity	molecular_function	Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0015164	glucuronoside transmembrane transporter activity	molecular_function	Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	molecular_function	Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0015166	polyol transmembrane transporter activity	molecular_function	Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.
GO:0015167	arabitol transmembrane transporter activity	molecular_function	Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
GO:0015168	glycerol transmembrane transporter activity	molecular_function	Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
GO:0015169	glycerol-3-phosphate transmembrane transporter activity	molecular_function	Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.
GO:0015170	propanediol transmembrane transporter activity	molecular_function	Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
GO:0015171	amino acid transmembrane transporter activity	molecular_function	Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
GO:0015172	acidic amino acid transmembrane transporter activity	molecular_function	Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.
GO:0015173	aromatic amino acid transmembrane transporter activity	molecular_function	Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.
GO:0015174	basic amino acid transmembrane transporter activity	molecular_function	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.
GO:0015175	neutral L-amino acid transmembrane transporter activity	molecular_function	Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.
GO:0015179	L-amino acid transmembrane transporter activity	molecular_function	Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
GO:0015180	L-alanine transmembrane transporter activity	molecular_function	Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.
GO:0015182	L-asparagine transmembrane transporter activity	molecular_function	Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.
GO:0015183	L-aspartate transmembrane transporter activity	molecular_function	Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.
GO:0015184	L-cystine transmembrane transporter activity	molecular_function	Enables the transfer of L-cystine from one side of a membrane to the other.
GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	molecular_function	Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).
GO:0015186	L-glutamine transmembrane transporter activity	molecular_function	Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.
GO:0015187	glycine transmembrane transporter activity	molecular_function	Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
GO:0015188	L-isoleucine transmembrane transporter activity	molecular_function	Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.
GO:0015189	L-lysine transmembrane transporter activity	molecular_function	Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
GO:0015190	L-leucine transmembrane transporter activity	molecular_function	Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.
GO:0015191	L-methionine transmembrane transporter activity	molecular_function	Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.
GO:0015192	L-phenylalanine transmembrane transporter activity	molecular_function	Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.
GO:0015193	L-proline transmembrane transporter activity	molecular_function	Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.
GO:0015194	L-serine transmembrane transporter activity	molecular_function	Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.
GO:0015195	L-threonine transmembrane transporter activity	molecular_function	Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.
GO:0015196	L-tryptophan transmembrane transporter activity	molecular_function	Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0015199	amino-acid betaine transmembrane transporter activity	molecular_function	Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid.
GO:0015200	methylammonium transmembrane transporter activity	molecular_function	Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.
GO:0015203	polyamine transmembrane transporter activity	molecular_function	Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.
GO:0015204	urea transmembrane transporter activity	molecular_function	Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
GO:0015205	nucleobase transmembrane transporter activity	molecular_function	Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.
GO:0015207	adenine transmembrane transporter activity	molecular_function	Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.
GO:0015208	guanine transmembrane transporter activity	molecular_function	Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.
GO:0015209	cytosine transmembrane transporter activity	molecular_function	Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.
GO:0015210	uracil transmembrane transporter activity	molecular_function	Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.
GO:0015211	purine nucleoside transmembrane transporter activity	molecular_function	Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.
GO:0015212	cytidine transmembrane transporter activity	molecular_function	Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.
GO:0015213	uridine transmembrane transporter activity	molecular_function	Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
GO:0015214	pyrimidine nucleoside transmembrane transporter activity	molecular_function	Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.
GO:0015215	nucleotide transmembrane transporter activity	molecular_function	Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.
GO:0015216	purine nucleotide transmembrane transporter activity	molecular_function	Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
GO:0015217	ADP transmembrane transporter activity	molecular_function	Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.
GO:0015218	pyrimidine nucleotide transmembrane transporter activity	molecular_function	Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
GO:0015220	choline transmembrane transporter activity	molecular_function	Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
GO:0015221	lipopolysaccharide transmembrane transporter activity	molecular_function	Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
GO:0015224	biopterin transmembrane transporter activity	molecular_function	Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
GO:0015225	biotin transmembrane transporter activity	molecular_function	Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
GO:0015226	carnitine transmembrane transporter activity	molecular_function	Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
GO:0015227	acyl carnitine transmembrane transporter activity	molecular_function	Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.
GO:0015228	coenzyme A transmembrane transporter activity	molecular_function	Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0015229	L-ascorbic acid transmembrane transporter activity	molecular_function	Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.
GO:0015230	FAD transmembrane transporter activity	molecular_function	Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
GO:0015231	5-formyltetrahydrofolate transmembrane transporter activity	molecular_function	Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.
GO:0015232	heme transmembrane transporter activity	molecular_function	Enables the transfer of heme from one side of a membrane to the other.
GO:0015233	pantothenate transmembrane transporter activity	molecular_function	Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0015234	thiamine transmembrane transporter activity	molecular_function	Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0015243	cycloheximide transmembrane transporter activity	molecular_function	Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
GO:0015244	fluconazole transmembrane transporter activity	molecular_function	Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
GO:0015245	fatty acid transmembrane transporter activity	molecular_function	Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0015247	aminophospholipid flippase activity	molecular_function	Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.
GO:0015248	sterol transporter activity	molecular_function	Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0015250	water channel activity	molecular_function	Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0015252	proton channel activity	molecular_function	Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0015254	glycerol channel activity	molecular_function	Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0015255	propanediol channel activity	molecular_function	Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0015264	methylammonium channel activity	molecular_function	Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2.
GO:0015265	urea channel activity	molecular_function	Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0015267	channel activity	molecular_function	Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0015269	calcium-activated potassium channel activity	molecular_function	Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
GO:0015271	outward rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.
GO:0015272	ATP-activated inward rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
GO:0015274	organellar voltage-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.
GO:0015275	stretch-activated, monoatomic cation-selective, calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.
GO:0015276	ligand-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0015277	kainate selective glutamate receptor activity	molecular_function	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
GO:0015278	calcium-release channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
GO:0015279	store-operated calcium channel activity	molecular_function	A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
GO:0015280	ligand-gated sodium channel activity	molecular_function	Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0015284	fructose uniporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).
GO:0015288	porin activity	molecular_function	Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0015291	secondary active transmembrane transporter activity	molecular_function	Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.
GO:0015292	uniporter activity	molecular_function	Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.
GO:0015293	symporter activity	molecular_function	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
GO:0015294	solute:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).
GO:0015295	solute:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).
GO:0015296	monoatomic anion:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).
GO:0015297	antiporter activity	molecular_function	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
GO:0015304	glucose uniporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in).
GO:0015306	sialate:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).
GO:0015309	cycloheximide:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).
GO:0015310	benomyl:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).
GO:0015311	monoamine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).
GO:0015312	polyamine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
GO:0015313	fluconazole:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).
GO:0015314	aminotriazole:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).
GO:0015315	organophosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out).
GO:0015317	phosphate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).
GO:0015318	inorganic molecular entity transmembrane transporter activity	molecular_function	Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.
GO:0015319	sodium:inorganic phosphate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in).
GO:0015322	secondary active oligopeptide transmembrane transporter activity	molecular_function	Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GO:0015324	peptide-acetyl-CoA secondary active transmembrane transporter activity	molecular_function	Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0015325	acetyl-CoA:CoA antiporter activity	molecular_function	Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).
GO:0015327	cystine:glutamate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).
GO:0015328	cystine secondary active transmembrane transporter activity	molecular_function	Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0015330	high-affinity glutamine transmembrane transporter activity	molecular_function	Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015333	peptide:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.
GO:0015334	high-affinity oligopeptide transmembrane transporter activity	molecular_function	Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0015341	zinc efflux active transmembrane transporter activity	molecular_function	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.
GO:0015343	siderophore-iron transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).
GO:0015344	siderophore uptake transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).
GO:0015345	ferric enterobactin:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).
GO:0015346	ferric triacetylfusarinine C:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).
GO:0015347	sodium-independent organic anion transmembrane transporter activity	molecular_function	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.
GO:0015349	thyroid hormone transmembrane transporter activity	molecular_function	Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
GO:0015350	methotrexate transmembrane transporter activity	molecular_function	Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
GO:0015351	bilirubin secondary active transmembrane transporter activity	molecular_function	Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	molecular_function	Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.
GO:0015360	acetate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).
GO:0015361	low-affinity sodium:dicarboxylate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0015362	high-affinity sodium:dicarboxylate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015364	dicarboxylate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out).
GO:0015366	malate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).
GO:0015367	oxoglutarate:malate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
GO:0015368	calcium:monoatomic cation antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).
GO:0015369	calcium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
GO:0015370	solute:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).
GO:0015371	galactose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).
GO:0015373	monoatomic anion:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic anion(out) + Na+(out) = monoatomic anion(in) + Na+(in).
GO:0015374	neutral, basic amino acid:sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).
GO:0015375	glycine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
GO:0015377	chloride:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).
GO:0015378	sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).
GO:0015379	potassium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).
GO:0015381	high-affinity sulfate transmembrane transporter activity	molecular_function	Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations.
GO:0015382	sodium:sulfate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).
GO:0015383	sulfate:bicarbonate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).
GO:0015385	sodium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
GO:0015386	potassium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).
GO:0015387	potassium:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).
GO:0015389	pyrimidine- and adenosine-specific:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenosine)(out) + Na+(out) = (pyrimidine nucleoside or adenosine)(in) + Na+(in).
GO:0015390	purine-specific nucleoside:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).
GO:0015391	nucleobase:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).
GO:0015394	uridine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).
GO:0015395	nucleoside transmembrane transporter activity, down a concentration gradient	molecular_function	Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.
GO:0015398	high-affinity secondary active ammonium transmembrane transporter activity	molecular_function	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015399	primary active transmembrane transporter activity	molecular_function	Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical such as ATP hydrolysis, redox energy and photon energy.
GO:0015400	low-affinity secondary active ammonium transmembrane transporter activity	molecular_function	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0015401	urea:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).
GO:0015407	ABC-type monosaccharide transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.
GO:0015408	ABC-type ferric iron transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).
GO:0015410	ABC-type manganese transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).
GO:0015411	ABC-type taurine transporter transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).
GO:0015412	ABC-type molybdate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).
GO:0015413	ABC-type nickel transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).
GO:0015414	ABC-type nitrate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).
GO:0015415	ATPase-coupled phosphate ion transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).
GO:0015416	ABC-type phosphonate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).
GO:0015417	ABC-type polyamine transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).
GO:0015418	ABC-type quaternary ammonium compound transporting activity	molecular_function	Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H+ + phosphate + quaternary ammonium(in).
GO:0015419	ABC-type sulfate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).
GO:0015420	ABC-type vitamin B12 transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.
GO:0015421	ABC-type oligopeptide transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).
GO:0015422	ABC-type oligosaccharide transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).
GO:0015423	ABC-type maltose transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).
GO:0015424	ABC-type amino acid transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).
GO:0015425	ATPase-coupled nonpolar-amino acid transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).
GO:0015426	ATPase-coupled polar amino acid-transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).
GO:0015430	ABC-type glycerol-3-phosphate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).
GO:0015431	ABC-type glutathione S-conjugate transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).
GO:0015432	ABC-type bile acid transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.
GO:0015433	ABC-type peptide antigen transporter activity	molecular_function	Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.
GO:0015434	ABC-type cadmium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).
GO:0015436	ABC-type capsular-polysaccharide transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).
GO:0015437	lipopolysaccharide floppase activity	molecular_function	Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0015438	ABC-type teichoic acid transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).
GO:0015439	ABC-type heme transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).
GO:0015440	ABC-type peptide transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.
GO:0015441	ABC-type beta-glucan transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).
GO:0015444	P-type magnesium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) = ADP + phosphate + Mg2+(in).
GO:0015445	P-type silver transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) = ADP + phosphate + Ag+(out).
GO:0015446	ATPase-coupled arsenite transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).
GO:0015450	protein-transporting ATPase activity	molecular_function	Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
GO:0015451	decarboxylation-driven active transmembrane transporter activity	molecular_function	Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
GO:0015452	methyl transfer-driven active transmembrane transporter activity	molecular_function	Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	molecular_function	Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
GO:0015454	light-driven active monoatomic ion transmembrane transporter activity	molecular_function	Active transport of an ion across a membrane, driven by light.
GO:0015459	potassium channel regulator activity	molecular_function	Binds to and modulates the activity of a potassium channel.
GO:0015462	ABC-type protein transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).
GO:0015464	acetylcholine receptor activity	molecular_function	Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0015467	G-protein activated inward rectifier potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
GO:0015471	nucleoside-specific channel forming porin activity	molecular_function	Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0015473	fimbrial usher porin activity	molecular_function	A porin that acts in the assembly of fimbria together with fimbrial chaperone.
GO:0015474	autotransporter activity	molecular_function	Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.
GO:0015475	adhesin autotransporter activity	molecular_function	Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.
GO:0015476	hemaglutinin autotransporter activity	molecular_function	Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.
GO:0015478	oligosaccharide transporting porin activity	molecular_function	Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0015481	maltose transporting porin activity	molecular_function	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0015483	long-chain fatty acid transporting porin activity	molecular_function	Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
GO:0015485	cholesterol binding	molecular_function	Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0015486	glycoside-pentoside-hexuronide:cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.
GO:0015487	melibiose:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).
GO:0015488	glucuronide:cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).
GO:0015489	putrescine transmembrane transporter activity	molecular_function	Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
GO:0015492	phenylalanine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).
GO:0015493	lysine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).
GO:0015494	aromatic amino acid:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).
GO:0015495	gamma-aminobutyric acid:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).
GO:0015496	putrescine:ornithine antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).
GO:0015498	pantothenate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).
GO:0015499	formate transmembrane transporter activity	molecular_function	Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
GO:0015501	glutamate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).
GO:0015503	glutathione-regulated potassium exporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
GO:0015504	cytosine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).
GO:0015505	uracil:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).
GO:0015506	nucleoside:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).
GO:0015513	high-affinity secondary active nitrite transmembrane transporter activity	molecular_function	Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0015514	nitrite efflux transmembrane transporter activity	molecular_function	Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.
GO:0015515	citrate:succinate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
GO:0015516	tartrate:succinate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).
GO:0015517	galactose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).
GO:0015518	arabinose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).
GO:0015519	D-xylose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).
GO:0015520	tetracycline:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).
GO:0015526	hexose-phosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out).
GO:0015527	glycerol-phosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out).
GO:0015528	lactose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).
GO:0015529	raffinose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).
GO:0015530	shikimate transmembrane transporter activity	molecular_function	Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.
GO:0015531	citrate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).
GO:0015532	alpha-ketoglutarate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).
GO:0015533	shikimate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).
GO:0015535	fucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).
GO:0015537	xanthosine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).
GO:0015538	sialic acid:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).
GO:0015539	hexuronate:monoatomic cation symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.
GO:0015540	3-hydroxyphenyl propionate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).
GO:0015541	secondary active cyanate transmembrane transporter activity	molecular_function	Enables the transfer of cyanate from one side of a membrane to the other.
GO:0015544	phenyl propionate uniporter activity	molecular_function	Enables the transfer of phenyl propionate from one side of a membrane to the other.
GO:0015545	bicyclomycin transmembrane transporter activity	molecular_function	Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
GO:0015546	sulfathiazole transmembrane transporter activity	molecular_function	Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group.
GO:0015548	organomercurial transmembrane transporter activity	molecular_function	Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom.
GO:0015550	galacturonate transmembrane transporter activity	molecular_function	Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
GO:0015551	3-hydroxyphenyl propanoate transmembrane transporter activity	molecular_function	Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.
GO:0015552	propionate transmembrane transporter activity	molecular_function	Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.
GO:0015553	xanthosine transmembrane transporter activity	molecular_function	Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.
GO:0015554	tartrate transmembrane transporter activity	molecular_function	Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.
GO:0015556	C4-dicarboxylate transmembrane transporter activity	molecular_function	Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.
GO:0015558	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	molecular_function	Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.
GO:0015561	rhamnose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).
GO:0015562	efflux transmembrane transporter activity	molecular_function	Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
GO:0015565	threonine efflux transmembrane transporter activity	molecular_function	Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.
GO:0015567	alkane transmembrane transporter activity	molecular_function	Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.
GO:0015568	L-idonate transmembrane transporter activity	molecular_function	Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
GO:0015571	N-acetylgalactosamine transmembrane transporter activity	molecular_function	Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
GO:0015572	N-acetylglucosamine transmembrane transporter activity	molecular_function	Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
GO:0015573	beta-glucoside transmembrane transporter activity	molecular_function	Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
GO:0015574	trehalose transmembrane transporter activity	molecular_function	Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.
GO:0015575	mannitol transmembrane transporter activity	molecular_function	Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
GO:0015576	sorbitol transmembrane transporter activity	molecular_function	Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.
GO:0015577	galactitol transmembrane transporter activity	molecular_function	Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
GO:0015578	mannose transmembrane transporter activity	molecular_function	Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
GO:0015591	D-ribose transmembrane transporter activity	molecular_function	Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
GO:0015592	methylgalactoside transmembrane transporter activity	molecular_function	Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
GO:0015593	allose transmembrane transporter activity	molecular_function	Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
GO:0015594	ABC-type putrescine transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).
GO:0015599	ATPase-coupled L-glutamine transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).
GO:0015603	iron chelate transmembrane transporter activity	molecular_function	Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
GO:0015605	organophosphate ester transmembrane transporter activity	molecular_function	Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.
GO:0015606	spermidine transmembrane transporter activity	molecular_function	Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
GO:0015607	ABC-type fatty-acyl-CoA transporter activity	molecular_function	Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.
GO:0015608	carbohydrate-importing ABC transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).
GO:0015611	ABC-type D-ribose transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).
GO:0015612	ABC-type L-arabinose transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in).
GO:0015614	ABC-type D-xylose transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).
GO:0015615	D-allose-importing ATPase activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).
GO:0015616	DNA translocase activity	molecular_function	Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis.
GO:0015620	ferric-enterobactin transmembrane transporter activity	molecular_function	Enables the transfer of ferric-enterobactin from one side of a membrane to the other.
GO:0015621	ferric triacetylfusarinine C transmembrane transporter activity	molecular_function	Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.
GO:0015624	ABC-type ferric-enterobactin transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).
GO:0015625	ABC-type ferric hydroxamate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).
GO:0015626	L-diaminopimelate transmembrane transporter activity	molecular_function	Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.
GO:0015627	type II protein secretion system complex	cellular_component	A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
GO:0015628	protein secretion by the type II secretion system	biological_process	The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.
GO:0015629	actin cytoskeleton	cellular_component	The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
GO:0015630	microtubule cytoskeleton	cellular_component	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
GO:0015631	tubulin binding	molecular_function	Binding to monomeric or multimeric forms of tubulin, including microtubules.
GO:0015633	ABC-type zinc transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).
GO:0015636	short-chain fatty acid transmembrane transporter activity	molecular_function	Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0015638	microcin transmembrane transporter activity	molecular_function	Enables the transfer of a microcin from one side of a membrane to the other.
GO:0015640	peptidoglycan peptide transmembrane transporter activity	molecular_function	Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.
GO:0015643	toxic substance binding	molecular_function	Binding to a toxic substance, a poisonous substance that causes damage to biological systems.
GO:0015645	fatty acid ligase activity	molecular_function	Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.
GO:0015647	peptidoglycan transmembrane transporter activity	molecular_function	Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.
GO:0015648	lipid-linked peptidoglycan transporter activity	molecular_function	Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.
GO:0015649	2-keto-3-deoxygluconate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).
GO:0015650	lactate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).
GO:0015651	quaternary ammonium group transmembrane transporter activity	molecular_function	Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
GO:0015652	quaternary ammonium group:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).
GO:0015653	glycine betaine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).
GO:0015654	tellurite transmembrane transporter activity	molecular_function	Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.
GO:0015655	alanine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).
GO:0015657	branched-chain amino acid:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).
GO:0015658	branched-chain amino acid transmembrane transporter activity	molecular_function	Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.
GO:0015660	formate efflux transmembrane transporter activity	molecular_function	Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.
GO:0015661	L-lysine efflux transmembrane transporter activity	molecular_function	Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.
GO:0015662	P-type ion transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
GO:0015663	nicotinamide mononucleotide transmembrane transporter activity	molecular_function	Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.
GO:0015665	alcohol transmembrane transporter activity	molecular_function	Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.
GO:0015666	restriction endodeoxyribonuclease activity	molecular_function	Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
GO:0015667	site-specific DNA-methyltransferase (cytosine-N4-specific) activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
GO:0015668	type III site-specific deoxyribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.
GO:0015669	gas transport	biological_process	The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015670	carbon dioxide transport	biological_process	The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015671	oxygen transport	biological_process	The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015673	silver ion transport	biological_process	The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015675	nickel cation transport	biological_process	The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015676	vanadium ion transport	biological_process	The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015677	copper ion import	biological_process	The directed movement of copper ions into a cell or organelle.
GO:0015679	plasma membrane copper ion transport	biological_process	The directed movement of copper ions across the plasma membrane.
GO:0015680	protein maturation by copper ion transfer	biological_process	A process that contributes to the delivery of copper ions to a target protein.
GO:0015685	ferric-enterobactin import into cell	biological_process	A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.
GO:0015686	ferric triacetylfusarinine C import into cell	biological_process	The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015687	ferric-hydroxamate import into cell	biological_process	A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors.
GO:0015689	molybdate ion transport	biological_process	The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.
GO:0015690	aluminum cation transport	biological_process	The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015691	cadmium ion transport	biological_process	The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015692	lead ion transport	biological_process	The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015693	magnesium ion transport	biological_process	The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015694	mercury ion transport	biological_process	The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015695	organic cation transport	biological_process	The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.
GO:0015697	quaternary ammonium group transport	biological_process	The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
GO:0015698	inorganic anion transport	biological_process	The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
GO:0015699	antimonite transport	biological_process	The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015700	arsenite transport	biological_process	The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015701	bicarbonate transport	biological_process	The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015702	chlorate transport	biological_process	The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015703	chromate transport	biological_process	The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015704	cyanate transport	biological_process	The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015705	iodide transport	biological_process	The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015706	nitrate transmembrane transport	biological_process	The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015707	nitrite transport	biological_process	The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015708	silicic acid import across plasma membrane	biological_process	The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
GO:0015709	thiosulfate transport	biological_process	The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015710	tellurite transport	biological_process	The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015711	organic anion transport	biological_process	The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GO:0015712	hexose phosphate transport	biological_process	The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015713	phosphoglycerate transmembrane transport	biological_process	The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015714	phosphoenolpyruvate transport	biological_process	The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015715	nucleotide-sulfate transport	biological_process	The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015716	organic phosphonate transport	biological_process	The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).
GO:0015717	triose phosphate transport	biological_process	The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015718	monocarboxylic acid transport	biological_process	The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015719	allantoate transport	biological_process	The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015720	allantoin transport	biological_process	The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015721	bile acid and bile salt transport	biological_process	The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015722	canalicular bile acid transport	biological_process	Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
GO:0015723	bilirubin transport	biological_process	The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015724	formate transport	biological_process	The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015726	L-idonate transmembrane transport	biological_process	The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
GO:0015727	lactate transport	biological_process	The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
GO:0015728	mevalonate transport	biological_process	The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015729	oxaloacetate transport	biological_process	The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015730	propanoate transmembrane transport	biological_process	The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015731	3-hydroxyphenyl propanoate transport	biological_process	The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015732	prostaglandin transport	biological_process	The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015733	shikimate transmembrane transport	biological_process	The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015734	taurine transport	biological_process	The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015735	uronic acid transmembrane transport	biological_process	The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015736	hexuronate transmembrane transport	biological_process	The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.
GO:0015737	galacturonate transmembrane transport	biological_process	The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015738	glucuronate transmembrane transport	biological_process	The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015739	sialic acid transport	biological_process	The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015740	C4-dicarboxylate transport	biological_process	The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.
GO:0015741	fumarate transport	biological_process	The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015742	alpha-ketoglutarate transport	biological_process	The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015743	malate transport	biological_process	The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015744	succinate transport	biological_process	The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015745	tartrate transmembrane transport	biological_process	The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015746	citrate transport	biological_process	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015747	urate transport	biological_process	The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015748	organophosphate ester transport	biological_process	The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.
GO:0015749	monosaccharide transmembrane transport	biological_process	The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
GO:0015750	pentose transmembrane transport	biological_process	The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.
GO:0015751	arabinose transmembrane transport	biological_process	The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015752	D-ribose transmembrane transport	biological_process	The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
GO:0015753	D-xylose transmembrane transport	biological_process	The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
GO:0015754	allose transmembrane transport	biological_process	The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
GO:0015755	fructose transmembrane transport	biological_process	The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
GO:0015756	fucose transmembrane transport	biological_process	The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
GO:0015757	galactose transmembrane transport	biological_process	The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
GO:0015759	beta-glucoside transport	biological_process	The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
GO:0015760	glucose-6-phosphate transport	biological_process	The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
GO:0015761	mannose transmembrane transport	biological_process	The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
GO:0015762	rhamnose transmembrane transport	biological_process	The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
GO:0015763	N-acetylgalactosamine transport	biological_process	The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
GO:0015764	N-acetylglucosamine transport	biological_process	The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015765	methylgalactoside transport	biological_process	The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
GO:0015766	disaccharide transport	biological_process	The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.
GO:0015767	lactose transport	biological_process	The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
GO:0015768	maltose transport	biological_process	The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.
GO:0015769	melibiose transport	biological_process	The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
GO:0015770	sucrose transport	biological_process	The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.
GO:0015771	trehalose transport	biological_process	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
GO:0015772	oligosaccharide transport	biological_process	The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
GO:0015773	raffinose transport	biological_process	The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
GO:0015774	polysaccharide transport	biological_process	The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0015775	beta-glucan transport	biological_process	The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
GO:0015776	capsular polysaccharide transport	biological_process	The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0015777	teichoic acid transport	biological_process	The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
GO:0015778	hexuronide transmembrane transport	biological_process	The directed movement of hexuronide across a membrane. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.
GO:0015779	glucuronoside transport	biological_process	The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
GO:0015780	nucleotide-sugar transmembrane transport	biological_process	The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0015782	CMP-N-acetylneuraminate transmembrane transport	biological_process	The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015783	GDP-fucose transmembrane transport	biological_process	The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
GO:0015786	UDP-glucose transmembrane transport	biological_process	The process in which UDP-glucose is transported across a membrane.
GO:0015787	UDP-glucuronic acid transmembrane transport	biological_process	The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
GO:0015789	UDP-N-acetylgalactosamine transmembrane transport	biological_process	The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0015790	UDP-xylose transmembrane transport	biological_process	The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.
GO:0015791	polyol transmembrane transport	biological_process	The directed movement of polyols, any polyhydric alcohol, across a membrane.
GO:0015792	arabinitol transmembrane transport	biological_process	The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
GO:0015793	glycerol transmembrane transport	biological_process	The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
GO:0015794	glycerol-3-phosphate transmembrane transport	biological_process	The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol.
GO:0015795	sorbitol transmembrane transport	biological_process	The directed movement of sorbitol across a membrane. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.
GO:0015796	galactitol transmembrane transport	biological_process	The directed movement of galactitol across a membrane. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
GO:0015797	mannitol transmembrane transport	biological_process	The directed movement of mannitol across a membrane. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
GO:0015798	myo-inositol transport	biological_process	The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.
GO:0015799	propanediol transport	biological_process	The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
GO:0015800	acidic amino acid transport	biological_process	The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015801	aromatic amino acid transport	biological_process	The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015802	basic amino acid transport	biological_process	The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015803	branched-chain amino acid transport	biological_process	The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.
GO:0015804	neutral amino acid transport	biological_process	The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015805	S-adenosyl-L-methionine transport	biological_process	The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015806	S-methylmethionine transport	biological_process	The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015807	L-amino acid transport	biological_process	The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015808	L-alanine transport	biological_process	The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015810	aspartate transmembrane transport	biological_process	The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015811	L-cystine transport	biological_process	The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015812	gamma-aminobutyric acid transport	biological_process	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015813	L-glutamate transmembrane transport	biological_process	The directed movement of L-glutamate across a membrane.
GO:0015814	p-aminobenzoyl-glutamate transport	biological_process	The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015816	glycine transport	biological_process	The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015817	histidine transport	biological_process	The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015818	isoleucine transport	biological_process	The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015819	lysine transport	biological_process	The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015820	leucine transport	biological_process	The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015821	methionine transport	biological_process	The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015822	ornithine transport	biological_process	The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015823	phenylalanine transport	biological_process	The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015824	proline transport	biological_process	The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015825	L-serine transport	biological_process	The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015826	threonine transport	biological_process	The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015827	tryptophan transport	biological_process	The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015828	tyrosine transport	biological_process	The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015829	valine transport	biological_process	The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015830	diaminopimelate transport	biological_process	The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015833	peptide transport	biological_process	The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015834	peptidoglycan-associated peptide transport	biological_process	The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.
GO:0015835	peptidoglycan transport	biological_process	The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015836	lipid-linked peptidoglycan transport	biological_process	The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015837	amine transport	biological_process	The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015838	amino-acid betaine transport	biological_process	The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015839	cadaverine transport	biological_process	The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015840	urea transport	biological_process	The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
GO:0015841	chromaffin granule amine transport	biological_process	The directed movement of amines into, out of or within chromaffin granules.
GO:0015842	aminergic neurotransmitter loading into synaptic vesicle	biological_process	The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
GO:0015843	methylammonium transport	biological_process	The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015844	monoamine transport	biological_process	The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015846	polyamine transport	biological_process	The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015847	putrescine transport	biological_process	The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
GO:0015848	spermidine transport	biological_process	The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015849	organic acid transport	biological_process	The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015850	organic hydroxy compound transport	biological_process	The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.
GO:0015851	nucleobase transport	biological_process	The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015853	adenine transport	biological_process	The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015854	guanine transport	biological_process	The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015855	pyrimidine nucleobase transport	biological_process	The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015856	cytosine transport	biological_process	The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015857	uracil transport	biological_process	The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015858	nucleoside transport	biological_process	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015859	intracellular nucleoside transport	biological_process	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.
GO:0015860	purine nucleoside transmembrane transport	biological_process	The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.
GO:0015861	cytidine transport	biological_process	The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015862	uridine transport	biological_process	The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015863	xanthosine transport	biological_process	The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015864	pyrimidine nucleoside transport	biological_process	The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015865	purine nucleotide transport	biological_process	The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.
GO:0015866	ADP transport	biological_process	The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015867	ATP transport	biological_process	The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015868	purine ribonucleotide transport	biological_process	The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.
GO:0015869	protein-DNA complex transport	biological_process	The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015870	acetylcholine transport	biological_process	The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
GO:0015871	choline transport	biological_process	The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
GO:0015872	dopamine transport	biological_process	The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0015874	norepinephrine transport	biological_process	The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
GO:0015876	acetyl-CoA transport	biological_process	The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
GO:0015877	biopterin transport	biological_process	The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
GO:0015878	biotin transport	biological_process	The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
GO:0015879	carnitine transport	biological_process	The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
GO:0015880	coenzyme A transport	biological_process	The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0015881	creatine transmembrane transport	biological_process	The directed movement of creatine across a membrane.
GO:0015882	L-ascorbic acid transmembrane transport	biological_process	The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.
GO:0015883	FAD transport	biological_process	The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
GO:0015884	folic acid transport	biological_process	The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GO:0015885	5-formyltetrahydrofolate transport	biological_process	The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.
GO:0015886	heme transport	biological_process	The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015887	pantothenate transmembrane transport	biological_process	The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0015888	thiamine transport	biological_process	The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0015889	cobalamin transport	biological_process	The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015890	nicotinamide mononucleotide transport	biological_process	The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.
GO:0015891	siderophore transport	biological_process	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015895	alkane transport	biological_process	The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.
GO:0015897	organomercurial transport	biological_process	The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom.
GO:0015899	aminotriazole transport	biological_process	The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.
GO:0015901	cycloheximide transport	biological_process	The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
GO:0015903	fluconazole transport	biological_process	The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
GO:0015904	tetracycline transmembrane transport	biological_process	The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
GO:0015905	bicyclomycin transmembrane transport	biological_process	The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
GO:0015908	fatty acid transport	biological_process	The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0015909	long-chain fatty acid transport	biological_process	The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.  A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0015910	long-chain fatty acid import into peroxisome	biological_process	The directed movement of a long-chain fatty acid into a peroxisome. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0015911	long-chain fatty acid import across plasma membrane	biological_process	The directed movement of a long-chain fatty acid from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0015912	short-chain fatty acid transport	biological_process	The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0015913	short-chain fatty acid transmembrane transport	biological_process	The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0015914	phospholipid transport	biological_process	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
GO:0015916	fatty-acyl-CoA transport	biological_process	The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A).
GO:0015917	aminophospholipid transport	biological_process	The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.
GO:0015918	sterol transport	biological_process	The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0015919	peroxisomal membrane transport	biological_process	The directed movement of substances to, from or across the peroxisomal membrane.
GO:0015920	lipopolysaccharide transport	biological_process	The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
GO:0015923	mannosidase activity	molecular_function	Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.
GO:0015924	mannosyl-oligosaccharide mannosidase activity	molecular_function	Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.
GO:0015925	galactosidase activity	molecular_function	Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.
GO:0015926	glucosidase activity	molecular_function	Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.
GO:0015927	trehalase activity	molecular_function	Catalysis of the hydrolysis of trehalose or a trehalose derivative.
GO:0015928	fucosidase activity	molecular_function	Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.
GO:0015929	hexosaminidase activity	molecular_function	Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
GO:0015930	glutamate synthase activity	molecular_function	Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.
GO:0015931	nucleobase-containing compound transport	biological_process	The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015932	nucleobase-containing compound transmembrane transporter activity	molecular_function	Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.
GO:0015934	large ribosomal subunit	cellular_component	The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).
GO:0015935	small ribosomal subunit	cellular_component	The smaller of the two subunits of a ribosome.
GO:0015936	coenzyme A metabolic process	biological_process	The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0015937	coenzyme A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0015938	coenzyme A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0015939	pantothenate metabolic process	biological_process	The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0015940	pantothenate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0015941	pantothenate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
GO:0015942	formate metabolic process	biological_process	The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
GO:0015943	formate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
GO:0015944	formate oxidation	biological_process	The chemical reactions and pathways by which formate is converted to CO2.
GO:0015945	methanol metabolic process	biological_process	The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
GO:0015946	methanol oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.
GO:0015947	methane metabolic process	biological_process	The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
GO:0015948	methanogenesis	biological_process	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
GO:0015949	nucleobase-containing small molecule interconversion	biological_process	The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
GO:0015950	purine nucleotide interconversion	biological_process	The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.
GO:0015951	purine ribonucleotide interconversion	biological_process	The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.
GO:0015952	purine deoxyribonucleotide interconversion	biological_process	The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.
GO:0015953	pyrimidine nucleotide interconversion	biological_process	The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.
GO:0015954	pyrimidine ribonucleotide interconversion	biological_process	The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.
GO:0015955	pyrimidine deoxyribonucleotide interconversion	biological_process	The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.
GO:0015956	bis(5'-nucleosidyl) oligophosphate metabolic process	biological_process	The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
GO:0015957	bis(5'-nucleosidyl) oligophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
GO:0015958	bis(5'-nucleosidyl) oligophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
GO:0015959	diadenosine polyphosphate metabolic process	biological_process	The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
GO:0015960	diadenosine polyphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
GO:0015961	diadenosine polyphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
GO:0015962	diadenosine triphosphate metabolic process	biological_process	The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
GO:0015963	diadenosine triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
GO:0015964	diadenosine triphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
GO:0015965	diadenosine tetraphosphate metabolic process	biological_process	The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
GO:0015966	diadenosine tetraphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
GO:0015967	diadenosine tetraphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
GO:0015968	stringent response	biological_process	A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.
GO:0015969	guanosine tetraphosphate metabolic process	biological_process	The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
GO:0015970	guanosine tetraphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
GO:0015971	guanosine tetraphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
GO:0015972	guanosine pentaphosphate metabolic process	biological_process	The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
GO:0015973	guanosine pentaphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
GO:0015974	guanosine pentaphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
GO:0015975	energy derivation by oxidation of reduced inorganic compounds	biological_process	The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.
GO:0015976	carbon utilization	biological_process	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
GO:0015977	carbon fixation	biological_process	A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
GO:0015979	photosynthesis	biological_process	The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
GO:0015980	energy derivation by oxidation of organic compounds	biological_process	The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.
GO:0015985	energy coupled proton transport, down electrochemical gradient	biological_process	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.
GO:0015986	proton motive force-driven ATP synthesis	biological_process	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
GO:0015987	GTP synthesis coupled proton transport	biological_process	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.
GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	biological_process	The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.
GO:0015990	electron transport coupled proton transport	biological_process	The transport of protons against an electrochemical gradient, using energy from electron transport.
GO:0015994	chlorophyll metabolic process	biological_process	The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.
GO:0015995	chlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
GO:0015996	chlorophyll catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.
GO:0016002	sulfite reductase activity	molecular_function	Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.
GO:0016004	phospholipase activator activity	molecular_function	Binds to and increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.
GO:0016005	phospholipase A2 activator activity	molecular_function	Binds to and increases the activity of the enzyme phospholipase A2.
GO:0016006	Nebenkern	cellular_component	A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.
GO:0016007	mitochondrial derivative	cellular_component	The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.
GO:0016008	major mitochondrial derivative	cellular_component	The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.
GO:0016009	minor mitochondrial derivative	cellular_component	The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.
GO:0016010	dystrophin-associated glycoprotein complex	cellular_component	A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.
GO:0016011	dystroglycan complex	cellular_component	A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
GO:0016012	sarcoglycan complex	cellular_component	A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.
GO:0016013	syntrophin complex	cellular_component	A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.
GO:0016014	dystrobrevin complex	cellular_component	A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.
GO:0016015	morphogen activity	molecular_function	Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.
GO:0016018	cyclosporin A binding	molecular_function	Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.
GO:0016019	peptidoglycan immune receptor activity	molecular_function	Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response.
GO:0016020	membrane	cellular_component	A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0016024	CDP-diacylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
GO:0016027	inaD signaling complex	cellular_component	A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.
GO:0016028	rhabdomere	cellular_component	The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.
GO:0016029	subrhabdomeral cisterna	cellular_component	A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.
GO:0016031	tRNA import into mitochondrion	biological_process	The process in which a tRNA is transported from the cytosol into the mitochondrial matrix.
GO:0016032	viral process	biological_process	A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0016034	maleylacetoacetate isomerase activity	molecular_function	Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.
GO:0016035	zeta DNA polymerase complex	cellular_component	A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.
GO:0016036	cellular response to phosphate starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
GO:0016037	light absorption	biological_process	The reception of a photon by a cell.
GO:0016038	absorption of visible light	biological_process	The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
GO:0016039	absorption of UV light	biological_process	The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
GO:0016040	glutamate synthase (NADH) activity	molecular_function	Catalysis of the reaction: 2 L-glutamate + NAD+ = 2-oxoglutarate + L-glutamine + H+ + NADH.
GO:0016041	glutamate synthase (ferredoxin) activity	molecular_function	Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.
GO:0016042	lipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0016043	cellular component organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016045	detection of bacterium	biological_process	The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
GO:0016046	detection of fungus	biological_process	The series of events in which a stimulus from a fungus is received and converted into a molecular signal.
GO:0016048	detection of temperature stimulus	biological_process	The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.
GO:0016049	cell growth	biological_process	The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
GO:0016050	vesicle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
GO:0016051	carbohydrate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0016052	carbohydrate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0016053	organic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
GO:0016054	organic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
GO:0016055	Wnt signaling pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
GO:0016056	rhodopsin mediated signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by the excitation of rhodopsin by a photon, and ending with the regulation of a downstream cellular process.
GO:0016057	regulation of membrane potential in photoreceptor cell	biological_process	Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.
GO:0016058	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	biological_process	Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.
GO:0016059	deactivation of rhodopsin mediated signaling	biological_process	The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
GO:0016060	metarhodopsin inactivation	biological_process	The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.
GO:0016061	regulation of light-activated channel activity	biological_process	Any process that modulates the frequency, rate or extent of light-activated channel activity.
GO:0016062	adaptation of rhodopsin mediated signaling	biological_process	The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.
GO:0016063	rhodopsin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
GO:0016064	immunoglobulin mediated immune response	biological_process	An immune response mediated by immunoglobulins, whether cell-bound or in solution.
GO:0016068	type I hypersensitivity	biological_process	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
GO:0016070	RNA metabolic process	biological_process	The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0016071	mRNA metabolic process	biological_process	The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
GO:0016072	rRNA metabolic process	biological_process	The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.
GO:0016073	snRNA metabolic process	biological_process	The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.
GO:0016074	sno(s)RNA metabolic process	biological_process	The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.
GO:0016075	rRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.
GO:0016076	snRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.
GO:0016077	sno(s)RNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.
GO:0016078	tRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.
GO:0016079	synaptic vesicle exocytosis	biological_process	Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
GO:0016080	synaptic vesicle targeting	biological_process	The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
GO:0016081	synaptic vesicle docking	biological_process	The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
GO:0016082	synaptic vesicle priming	biological_process	A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.
GO:0016084	myostimulatory hormone activity	molecular_function	The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.
GO:0016085	myoinhibitory hormone activity	molecular_function	The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.
GO:0016087	ecdysiostatic hormone activity	molecular_function	The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.
GO:0016090	prenol metabolic process	biological_process	The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
GO:0016091	prenol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
GO:0016092	prenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
GO:0016093	polyprenol metabolic process	biological_process	The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
GO:0016094	polyprenol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
GO:0016095	polyprenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
GO:0016098	monoterpenoid metabolic process	biological_process	The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.
GO:0016099	monoterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.
GO:0016100	monoterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.
GO:0016101	diterpenoid metabolic process	biological_process	The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.
GO:0016102	diterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
GO:0016103	diterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.
GO:0016104	triterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.
GO:0016105	triterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.
GO:0016106	sesquiterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.
GO:0016107	sesquiterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.
GO:0016108	tetraterpenoid metabolic process	biological_process	The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.
GO:0016109	tetraterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.
GO:0016110	tetraterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.
GO:0016111	polyterpenoid metabolic process	biological_process	The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units.
GO:0016112	polyterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.
GO:0016113	polyterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.
GO:0016114	terpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.
GO:0016115	terpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.
GO:0016116	carotenoid metabolic process	biological_process	The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
GO:0016117	carotenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
GO:0016118	carotenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
GO:0016119	carotene metabolic process	biological_process	The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.
GO:0016120	carotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.
GO:0016121	carotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.
GO:0016122	xanthophyll metabolic process	biological_process	The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.
GO:0016123	xanthophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.
GO:0016124	xanthophyll catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.
GO:0016125	sterol metabolic process	biological_process	The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0016126	sterol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0016127	sterol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0016128	phytosteroid metabolic process	biological_process	The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
GO:0016129	phytosteroid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
GO:0016130	phytosteroid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
GO:0016131	brassinosteroid metabolic process	biological_process	The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
GO:0016132	brassinosteroid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
GO:0016133	brassinosteroid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
GO:0016134	saponin metabolic process	biological_process	The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
GO:0016135	saponin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
GO:0016136	saponin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
GO:0016137	glycoside metabolic process	biological_process	The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
GO:0016138	glycoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
GO:0016139	glycoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
GO:0016143	S-glycoside metabolic process	biological_process	The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
GO:0016144	S-glycoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
GO:0016145	S-glycoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
GO:0016149	translation release factor activity, codon specific	molecular_function	A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.
GO:0016150	translation release factor activity, codon nonspecific	molecular_function	A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
GO:0016151	nickel cation binding	molecular_function	Binding to a nickel (Ni) cation.
GO:0016152	mercury (II) reductase activity	molecular_function	Catalysis of the reaction: H+ + Hg + NADP+ = Hg2+ + NADPH.
GO:0016153	urocanate hydratase activity	molecular_function	Catalysis of the reaction: 4-imidazolone-5-propanoate + H+ = trans-urocanate + H2O.
GO:0016154	pyrimidine-nucleoside phosphorylase activity	molecular_function	Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.
GO:0016155	formyltetrahydrofolate dehydrogenase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + H2O + NADP+ = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H+ + NADPH.
GO:0016156	fumarate reductase (NADH) activity	molecular_function	Catalysis of the reaction: NAD+ + succinate = fumarate + H+ + NADH.
GO:0016157	sucrose synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.
GO:0016158	3-phytase activity	molecular_function	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.
GO:0016159	muconolactone delta-isomerase activity	molecular_function	Catalysis of the reaction: (S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate.
GO:0016160	amylase activity	molecular_function	Catalysis of the hydrolysis of amylose or an amylose derivative.
GO:0016161	beta-amylase activity	molecular_function	Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.
GO:0016162	cellulose 1,4-beta-cellobiosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.
GO:0016163	nitrogenase activity	molecular_function	Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.
GO:0016165	linoleate 13S-lipoxygenase activity	molecular_function	Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
GO:0016166	phytoene dehydrogenase activity	molecular_function	Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.
GO:0016167	glial cell-derived neurotrophic factor receptor activity	molecular_function	Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0016168	chlorophyll binding	molecular_function	Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.
GO:0016169	bacteriochlorophyll c binding	molecular_function	Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
GO:0016170	interleukin-15 receptor binding	molecular_function	Binding to an interleukin-15 receptor.
GO:0016174	NAD(P)H oxidase H2O2-forming activity	molecular_function	Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.
GO:0016175	superoxide-generating NAD(P)H oxidase activity	molecular_function	Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.
GO:0016176	superoxide-generating NADPH oxidase activator activity	molecular_function	Binds to and increases the activity of the enzyme superoxide-generating NADPH oxidase.
GO:0016180	snRNA processing	biological_process	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.
GO:0016182	synaptic vesicle budding from endosome	biological_process	Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.
GO:0016183	synaptic vesicle coating	biological_process	The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.
GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane	biological_process	Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.
GO:0016188	synaptic vesicle maturation	biological_process	Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.
GO:0016189	synaptic vesicle to endosome fusion	biological_process	Fusion of a synaptic vesicle with an endosome.
GO:0016191	synaptic vesicle uncoating	biological_process	The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.
GO:0016192	vesicle-mediated transport	biological_process	A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0016197	endosomal transport	biological_process	The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
GO:0016198	axon choice point recognition	biological_process	The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.
GO:0016199	axon midline choice point recognition	biological_process	The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
GO:0016200	synaptic target attraction	biological_process	The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.
GO:0016201	synaptic target inhibition	biological_process	The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.
GO:0016202	regulation of striated muscle tissue development	biological_process	Any process that modulates the frequency, rate or extent of striated muscle development.
GO:0016203	muscle attachment	biological_process	The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
GO:0016204	determination of muscle attachment site	biological_process	The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.
GO:0016205	selenocysteine methyltransferase activity	molecular_function	Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.
GO:0016206	catechol O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.
GO:0016207	4-coumarate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
GO:0016208	AMP binding	molecular_function	Binding to AMP, adenosine monophosphate.
GO:0016209	antioxidant activity	molecular_function	Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0016210	naringenin-chalcone synthase activity	molecular_function	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.
GO:0016211	ammonia ligase activity	molecular_function	Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
GO:0016212	kynurenine-oxoglutarate transaminase activity	molecular_function	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
GO:0016213	linoleoyl-CoA desaturase activity	molecular_function	Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA).
GO:0016215	acyl-CoA desaturase activity	molecular_function	Catalysis of the reaction: AH2 + O2 + octadecanoyl-CoA = (9Z)-octadecenoyl-CoA + A + 2 H2O.
GO:0016216	isopenicillin-N synthase activity	molecular_function	Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = 2 H2O + isopenicillin N.
GO:0016217	N-ethylammeline chlorohydrolase activity	molecular_function	Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.
GO:0016218	polyketide synthase activity	molecular_function	Catalysis of a multistep reaction that produce polyketides through decarboxylative condensation of carboxylic acids. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.
GO:0016222	procollagen-proline 4-dioxygenase complex	cellular_component	A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
GO:0016223	beta-alanine-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.
GO:0016226	iron-sulfur cluster assembly	biological_process	The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
GO:0016229	steroid dehydrogenase activity	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
GO:0016230	sphingomyelin phosphodiesterase activator activity	molecular_function	Binds to and increases the activity of the enzyme sphingomyelin phosphodiesterase.
GO:0016231	beta-N-acetylglucosaminidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.
GO:0016232	HNK-1 sulfotransferase activity	molecular_function	Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).
GO:0016233	telomere capping	biological_process	A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.
GO:0016234	inclusion body	cellular_component	A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
GO:0016235	aggresome	cellular_component	An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.
GO:0016236	macroautophagy	biological_process	The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
GO:0016237	lysosomal microautophagy	biological_process	The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.
GO:0016239	positive regulation of macroautophagy	biological_process	Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
GO:0016240	autophagosome membrane docking	biological_process	The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
GO:0016241	regulation of macroautophagy	biological_process	Any process that modulates the frequency, rate or extent of macroautophagy.
GO:0016242	negative regulation of macroautophagy	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
GO:0016243	regulation of autophagosome size	biological_process	Any process that modulates the size of the autophagosome.
GO:0016247	channel regulator activity	molecular_function	Binds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
GO:0016248	channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a channel.
GO:0016250	N-sulfoglucosamine sulfohydrolase activity	molecular_function	Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.
GO:0016251	RNA polymerase II general transcription initiation factor activity	molecular_function	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and other small noncoding RNAs. For some small RNAs there is variability between species as to whether it is transcribed by RNA polymerase II or RNA polymerase III. However there are also rare exceptions, such as Trypanosoma brucei, where RNA polymerase I transcribes certain mRNAs in addition to its normal role in rRNA transcription.
GO:0016254	preassembly of GPI anchor in ER membrane	biological_process	The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.
GO:0016255	attachment of GPI anchor to protein	biological_process	A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.
GO:0016256	N-glycan processing to lysosome	biological_process	The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
GO:0016257	N-glycan processing to secreted and cell-surface N-glycans	biological_process	The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.
GO:0016258	N-glycan diversification	biological_process	The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.
GO:0016259	selenocysteine metabolic process	biological_process	The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.
GO:0016260	selenocysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.
GO:0016261	selenocysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.
GO:0016262	protein N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.
GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	molecular_function	Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.
GO:0016264	gap junction assembly	biological_process	Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.
GO:0016266	O-glycan processing	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.
GO:0016267	O-glycan processing, core 1	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.
GO:0016268	O-glycan processing, core 2	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.
GO:0016269	O-glycan processing, core 3	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.
GO:0016270	O-glycan processing, core 4	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.
GO:0016272	prefoldin complex	cellular_component	A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
GO:0016273	arginine N-methyltransferase activity	molecular_function	Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.
GO:0016274	protein-arginine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.
GO:0016278	lysine N-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.
GO:0016279	protein-lysine N-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
GO:0016281	eukaryotic translation initiation factor 4F complex	cellular_component	The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
GO:0016282	eukaryotic 43S preinitiation complex	cellular_component	A protein complex composed of the 40S ribosomal subunit plus eIF1, eIF1A, eIF3, eIF5, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
GO:0016286	small conductance calcium-activated potassium channel activity	molecular_function	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
GO:0016287	glycerone-phosphate O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.
GO:0016289	CoA hydrolase activity	molecular_function	Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.
GO:0016290	palmitoyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity	molecular_function	Catalysis of the reaction: tetradecanoyl-[ACP] + H2O = tetradecanoate + holo-[ACP] + H+.
GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity	molecular_function	Catalysis of the reaction: hexadecanoyl-[ACP] + H2O = H+ + hexadecanoate + holo-[ACP].
GO:0016297	acyl-[acyl-carrier-protein] hydrolase activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid.
GO:0016298	lipase activity	molecular_function	Catalysis of the hydrolysis of a lipid or phospholipid.
GO:0016300	tRNA (uracil) methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.
GO:0016301	kinase activity	molecular_function	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0016303	1-phosphatidylinositol-3-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H+.
GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H+.
GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:0016310	phosphorylation	biological_process	The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0016311	dephosphorylation	biological_process	The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
GO:0016312	inositol bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.
GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.
GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
GO:0016318	ommatidial rotation	biological_process	The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
GO:0016319	mushroom body development	biological_process	The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
GO:0016320	endoplasmic reticulum membrane fusion	biological_process	The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.
GO:0016321	female meiosis chromosome segregation	biological_process	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
GO:0016322	neuron remodeling	biological_process	The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
GO:0016323	basolateral plasma membrane	cellular_component	The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
GO:0016324	apical plasma membrane	cellular_component	The region of the plasma membrane located at the apical end of the cell.
GO:0016325	oocyte microtubule cytoskeleton organization	biological_process	Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.
GO:0016327	apicolateral plasma membrane	cellular_component	The apical end of the lateral plasma membrane of epithelial cells.
GO:0016328	lateral plasma membrane	cellular_component	The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
GO:0016330	second mitotic wave involved in compound eye morphogenesis	biological_process	A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.
GO:0016331	morphogenesis of embryonic epithelium	biological_process	The process in which the anatomical structures of embryonic epithelia are generated and organized.
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	biological_process	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.
GO:0016333	morphogenesis of follicular epithelium	biological_process	The process in which the anatomical structures of a follicular epithelium are generated and organized.
GO:0016334	establishment or maintenance of polarity of follicular epithelium	biological_process	Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.
GO:0016335	morphogenesis of larval imaginal disc epithelium	biological_process	The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.
GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium	biological_process	Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.
GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	biological_process	The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	biological_process	The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
GO:0016340	calcium-dependent cell-matrix adhesion	biological_process	The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.
GO:0016342	catenin complex	cellular_component	Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.
GO:0016344	meiotic chromosome movement towards spindle pole	biological_process	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.
GO:0016345	female meiotic chromosome movement towards spindle pole	biological_process	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.
GO:0016346	male meiotic chromosome movement towards spindle pole	biological_process	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.
GO:0016348	imaginal disc-derived leg joint morphogenesis	biological_process	The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.
GO:0016358	dendrite development	biological_process	The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.
GO:0016360	sensory organ precursor cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0016361	activin receptor activity, type I	molecular_function	Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.
GO:0016362	activin receptor activity, type II	molecular_function	Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
GO:0016363	nuclear matrix	cellular_component	The dense fibrillar network lying on the inner side of the nuclear membrane.
GO:0016401	palmitoyl-CoA oxidase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.
GO:0016402	pristanoyl-CoA oxidase activity	molecular_function	Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.
GO:0016403	dimethylargininase activity	molecular_function	Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.
GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.
GO:0016405	CoA-ligase activity	molecular_function	Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.
GO:0016406	carnitine O-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.
GO:0016407	acetyltransferase activity	molecular_function	Catalysis of the transfer of an acetyl group to an acceptor molecule.
GO:0016408	C-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.
GO:0016409	palmitoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.
GO:0016410	N-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.
GO:0016411	acylglycerol O-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.
GO:0016412	serine O-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule.
GO:0016413	O-acetyltransferase activity	molecular_function	Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.
GO:0016414	O-octanoyltransferase activity	molecular_function	Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.
GO:0016415	octanoyltransferase activity	molecular_function	Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.
GO:0016416	O-palmitoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.
GO:0016417	S-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.
GO:0016418	S-acetyltransferase activity	molecular_function	Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.
GO:0016419	S-malonyltransferase activity	molecular_function	Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.
GO:0016420	malonyltransferase activity	molecular_function	Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.
GO:0016421	CoA carboxylase activity	molecular_function	Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.
GO:0016423	tRNA (guanine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.
GO:0016426	tRNA (adenine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.
GO:0016427	tRNA (cytosine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.
GO:0016428	tRNA (cytosine-5-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.
GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine.
GO:0016430	tRNA (adenine-N6-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.
GO:0016432	tRNA-uridine aminocarboxypropyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.
GO:0016433	rRNA (adenine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.
GO:0016434	rRNA (cytosine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.
GO:0016435	rRNA (guanine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
GO:0016436	rRNA (uridine) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.
GO:0016438	tRNA-queuosine beta-mannosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose + queuosine34 in tRNA(Asp) = GDP + H+ + O-4''-alpha-D-mannosylqueuosine34 in tRNA(Asp).
GO:0016441	post-transcriptional gene silencing	biological_process	The inactivation of gene expression that occurs after transcription.
GO:0016442	RISC complex	cellular_component	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.
GO:0016443	bidentate ribonuclease III activity	molecular_function	Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.
GO:0016444	somatic cell DNA recombination	biological_process	Recombination occurring within or between DNA molecules in somatic cells.
GO:0016445	somatic diversification of immunoglobulins	biological_process	The somatic process that results in the generation of sequence diversity of immunoglobulins.
GO:0016446	somatic hypermutation of immunoglobulin genes	biological_process	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.
GO:0016447	somatic recombination of immunoglobulin gene segments	biological_process	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.
GO:0016453	C-acetyltransferase activity	molecular_function	Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.
GO:0016454	C-palmitoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.
GO:0016456	X chromosome located dosage compensation complex, transcription activating	cellular_component	An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.
GO:0016459	myosin complex	cellular_component	A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.
GO:0016460	myosin II complex	cellular_component	A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.
GO:0016461	unconventional myosin complex	cellular_component	A portmanteau term for myosins other than myosin II.
GO:0016462	pyrophosphatase activity	molecular_function	Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0016463	P-type zinc transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) = ADP + phosphate + Zn2+(out).
GO:0016464	chloroplast protein-transporting ATPase activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.
GO:0016465	chaperonin ATPase complex	cellular_component	Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.
GO:0016469	proton-transporting two-sector ATPase complex	cellular_component	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
GO:0016471	vacuolar proton-transporting V-type ATPase complex	cellular_component	A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
GO:0016472	sodium ion-transporting two-sector ATPase complex	cellular_component	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.
GO:0016473	sodium ion-transporting F-type ATPase complex	cellular_component	A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.
GO:0016474	sodium ion-transporting V-type ATPase complex	cellular_component	A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.
GO:0016475	detection of nuclear:cytoplasmic ratio	biological_process	The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.
GO:0016476	regulation of embryonic cell shape	biological_process	Any process that modulates the surface configuration of an embryonic cell.
GO:0016477	cell migration	biological_process	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.
GO:0016479	negative regulation of transcription by RNA polymerase I	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.
GO:0016480	negative regulation of transcription by RNA polymerase III	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
GO:0016482	cytosolic transport	biological_process	The directed movement of substances or organelles within the cytosol.
GO:0016483	tryptophan hydroxylase activator activity	molecular_function	Increases the activity of the enzyme tryptophase hydroxylase.
GO:0016485	protein processing	biological_process	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
GO:0016486	peptide hormone processing	biological_process	The generation of a mature peptide hormone by posttranslational processing of a prohormone.
GO:0016487	farnesol metabolic process	biological_process	The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
GO:0016488	farnesol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
GO:0016490	structural constituent of peritrophic membrane	molecular_function	The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.
GO:0016491	oxidoreductase activity	molecular_function	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016492	G protein-coupled neurotensin receptor activity	molecular_function	Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
GO:0016493	C-C chemokine receptor activity	molecular_function	Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
GO:0016494	C-X-C chemokine receptor activity	molecular_function	Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.
GO:0016495	C-X3-C chemokine receptor activity	molecular_function	Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.
GO:0016496	substance P receptor activity	molecular_function	Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.
GO:0016497	substance K receptor activity	molecular_function	Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.
GO:0016498	neuromedin K receptor activity	molecular_function	Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.
GO:0016499	orexin receptor activity	molecular_function	Combining with orexin to initiate a change in cell activity.
GO:0016500	protein-hormone receptor activity	molecular_function	Combining with a protein hormone to initiate a change in cell activity.
GO:0016501	prostacyclin receptor activity	molecular_function	Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.
GO:0016502	nucleotide receptor activity	molecular_function	Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.
GO:0016503	pheromone receptor activity	molecular_function	Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.
GO:0016504	peptidase activator activity	molecular_function	Binds to and increases the activity of a peptidase.
GO:0016505	peptidase activator activity involved in apoptotic process	molecular_function	Binds to and increases the activity of a peptidase that is involved in the apoptotic process.
GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	cellular_component	A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix.
GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO:0016513	core-binding factor complex	cellular_component	A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.
GO:0016514	SWI/SNF complex	cellular_component	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
GO:0016515	interleukin-13 receptor activity	molecular_function	Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0016516	interleukin-4 receptor complex	cellular_component	A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.
GO:0016517	interleukin-12 receptor activity	molecular_function	Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0016519	gastric inhibitory peptide receptor activity	molecular_function	Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.
GO:0016520	growth hormone-releasing hormone receptor activity	molecular_function	Combining with growth hormone-releasing hormone to initiate a change in cell activity.
GO:0016521	pituitary adenylate cyclase activating polypeptide activity	molecular_function	The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.
GO:0016524	latrotoxin receptor activity	molecular_function	Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0016525	negative regulation of angiogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
GO:0016528	sarcoplasm	cellular_component	The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.
GO:0016529	sarcoplasmic reticulum	cellular_component	A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
GO:0016530	metallochaperone activity	molecular_function	Binding to and delivering metal ions to a target protein.
GO:0016531	copper chaperone activity	molecular_function	Directly binding to and delivering copper ions to a target protein.
GO:0016532	superoxide dismutase copper chaperone activity	molecular_function	A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
GO:0016533	protein kinase 5 complex	cellular_component	A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent.
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	molecular_function	Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
GO:0016539	intein-mediated protein splicing	biological_process	The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.
GO:0016540	protein autoprocessing	biological_process	Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
GO:0016543	male courtship behavior, orientation prior to leg tapping and wing vibration	biological_process	The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.
GO:0016544	male courtship behavior, tapping to detect pheromone	biological_process	The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.
GO:0016545	male courtship behavior, veined wing vibration	biological_process	The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.
GO:0016546	male courtship behavior, proboscis-mediated licking	biological_process	The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.
GO:0016553	base conversion or substitution editing	biological_process	Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
GO:0016554	cytidine to uridine editing	biological_process	The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
GO:0016555	uridine to cytidine editing	biological_process	The conversion of a uridine residue to cytosine in an RNA molecule by amination.
GO:0016556	mRNA modification	biological_process	The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:0016557	peroxisome membrane biogenesis	biological_process	The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.
GO:0016558	protein import into peroxisome matrix	biological_process	The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.
GO:0016559	peroxisome fission	biological_process	The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
GO:0016560	protein import into peroxisome matrix, docking	biological_process	The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.
GO:0016561	protein import into peroxisome matrix, translocation	biological_process	The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.
GO:0016562	protein import into peroxisome matrix, receptor recycling	biological_process	The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.
GO:0016567	protein ubiquitination	biological_process	The process in which one or more ubiquitin groups are added to a protein.
GO:0016570	histone modification	biological_process	The covalent alteration of one or more amino acid residues within a histone protein.
GO:0016571	histone methylation	biological_process	The modification of histones by addition of methyl groups.
GO:0016573	histone acetylation	biological_process	The modification of a histone by the addition of an acetyl group.
GO:0016574	histone ubiquitination	biological_process	The modification of histones by addition of ubiquitin groups.
GO:0016575	histone deacetylation	biological_process	The modification of histones by removal of acetyl groups.
GO:0016577	histone demethylation	biological_process	The modification of histones by removal of methyl groups.
GO:0016578	histone deubiquitination	biological_process	The modification of histones by removal of ubiquitin groups.
GO:0016579	protein deubiquitination	biological_process	The removal of one or more ubiquitin groups from a protein.
GO:0016580	Sin3 complex	cellular_component	A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.
GO:0016581	NuRD complex	cellular_component	An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.
GO:0016586	RSC-type complex	cellular_component	A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.
GO:0016587	Isw1 complex	cellular_component	A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.
GO:0016589	NURF complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.
GO:0016590	ACF complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.
GO:0016591	RNA polymerase II, holoenzyme	cellular_component	A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.
GO:0016592	mediator complex	cellular_component	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
GO:0016593	Cdc73/Paf1 complex	cellular_component	A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
GO:0016594	glycine binding	molecular_function	Binding to glycine, aminoethanoic acid.
GO:0016595	glutamate binding	molecular_function	Binding to glutamate, the anion of 2-aminopentanedioic acid.
GO:0016596	thienylcyclohexylpiperidine binding	molecular_function	Binding to thienylcyclohexylpiperidine.
GO:0016597	amino acid binding	molecular_function	Binding to an amino acid, organic acids containing one or more amino substituents.
GO:0016598	protein arginylation	biological_process	The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.
GO:0016600	flotillin complex	cellular_component	A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.
GO:0016601	Rac protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
GO:0016602	CCAAT-binding factor complex	cellular_component	A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
GO:0016603	glutaminyl-peptide cyclotransferase activity	molecular_function	Catalysis of the reaction: N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4+.
GO:0016604	nuclear body	cellular_component	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
GO:0016605	PML body	cellular_component	A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
GO:0016606	LYSP100-associated nuclear domain	cellular_component	A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.
GO:0016607	nuclear speck	cellular_component	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
GO:0016608	growth hormone-releasing hormone activity	molecular_function	The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.
GO:0016610	nitrogenase complex	cellular_component	An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.
GO:0016611	iron-iron nitrogenase complex	cellular_component	An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.
GO:0016612	molybdenum-iron nitrogenase complex	cellular_component	An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.
GO:0016613	vanadium-iron nitrogenase complex	cellular_component	An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016615	malate dehydrogenase activity	molecular_function	Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016617	4-oxoproline reductase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.
GO:0016618	hydroxypyruvate reductase activity	molecular_function	Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016621	cinnamoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+.
GO:0016622	oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.
GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0016625	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016629	12-oxophytodienoate reductase activity	molecular_function	Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + H+ + NADPH.
GO:0016630	protochlorophyllide reductase activity	molecular_function	Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.
GO:0016631	enoyl-[acyl-carrier-protein] reductase activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.
GO:0016632	oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.
GO:0016633	galactonolactone dehydrogenase activity	molecular_function	Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.
GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.
GO:0016636	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016640	oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.
GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.
GO:0016643	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.
GO:0016648	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.
GO:0016649	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.
GO:0016651	oxidoreductase activity, acting on NAD(P)H	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016652	oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
GO:0016656	monodehydroascorbate reductase (NADH) activity	molecular_function	Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.
GO:0016657	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.
GO:0016663	oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.
GO:0016664	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016669	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.
GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.
GO:0016673	oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0016675	oxidoreductase activity, acting on a heme group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016677	oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.
GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016680	oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
GO:0016688	L-ascorbate peroxidase activity	molecular_function	Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.
GO:0016689	manganese peroxidase activity	molecular_function	Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.
GO:0016690	diarylpropane peroxidase activity	molecular_function	Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.
GO:0016691	chloride peroxidase activity	molecular_function	Catalysis of the reaction: 2 R-H + 2 chloride + H2O2 = 2 R-Cl + 2 H2O.
GO:0016692	NADH peroxidase activity	molecular_function	Catalysis of the reaction: H2O2 + NADH + H+ = 2 H2O + NAD+.
GO:0016695	oxidoreductase activity, acting on hydrogen as donor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.
GO:0016696	oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.
GO:0016697	oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.
GO:0016699	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
GO:0016703	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	molecular_function	Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
GO:0016707	gibberellin 3-beta-dioxygenase activity	molecular_function	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.
GO:0016708	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0016710	trans-cinnamate 4-monooxygenase activity	molecular_function	Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.
GO:0016711	flavonoid 3'-monooxygenase activity	molecular_function	Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.
GO:0016719	carotene 7,8-desaturase activity	molecular_function	Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.
GO:0016720	delta12-fatty acid dehydrogenase activity	molecular_function	Catalysis of the reaction: AH(2) + linoleate + O2 = A + crepenynate + 2 H2O.
GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.
GO:0016722	oxidoreductase activity, acting on metal ions	molecular_function	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.
GO:0016723	oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.
GO:0016724	oxidoreductase activity, acting on metal ions, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0016727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.
GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.
GO:0016730	oxidoreductase activity, acting on iron-sulfur proteins as donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016731	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0016732	oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.
GO:0016737	oxidoreductase activity, acting on reduced flavodoxin as donor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016738	oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.
GO:0016740	transferase activity	molecular_function	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0016741	transferase activity, transferring one-carbon groups	molecular_function	Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GO:0016742	hydroxymethyl-, formyl- and related transferase activity	molecular_function	Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).
GO:0016743	carboxyl- or carbamoyltransferase activity	molecular_function	Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
GO:0016744	transketolase or transaldolase activity	molecular_function	Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).
GO:0016746	acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	molecular_function	Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
GO:0016748	succinyltransferase activity	molecular_function	Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.
GO:0016749	N-succinyltransferase activity	molecular_function	Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.
GO:0016750	O-succinyltransferase activity	molecular_function	Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.
GO:0016751	S-succinyltransferase activity	molecular_function	Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.
GO:0016752	sinapoyltransferase activity	molecular_function	Catalysis of the transfer of a sinapoyl group to an acceptor molecule.
GO:0016753	O-sinapoyltransferase activity	molecular_function	Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.
GO:0016754	sinapoylglucose-malate O-sinapoyltransferase activity	molecular_function	Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.
GO:0016755	aminoacyltransferase activity	molecular_function	Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).
GO:0016756	glutathione gamma-glutamylcysteinyltransferase activity	molecular_function	Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
GO:0016757	glycosyltransferase activity	molecular_function	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
GO:0016758	hexosyltransferase activity	molecular_function	Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).
GO:0016759	cellulose synthase activity	molecular_function	Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).
GO:0016760	cellulose synthase (UDP-forming) activity	molecular_function	Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).
GO:0016761	cellulose synthase (GDP-forming) activity	molecular_function	Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).
GO:0016762	xyloglucan:xyloglucosyl transferase activity	molecular_function	Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.
GO:0016763	pentosyltransferase activity	molecular_function	Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	molecular_function	Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
GO:0016767	geranylgeranyl-diphosphate geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.
GO:0016768	spermine synthase activity	molecular_function	Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
GO:0016769	transferase activity, transferring nitrogenous groups	molecular_function	Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).
GO:0016772	transferase activity, transferring phosphorus-containing groups	molecular_function	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0016773	phosphotransferase activity, alcohol group as acceptor	molecular_function	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0016774	phosphotransferase activity, carboxyl group as acceptor	molecular_function	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	molecular_function	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).
GO:0016776	phosphotransferase activity, phosphate group as acceptor	molecular_function	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).
GO:0016778	diphosphotransferase activity	molecular_function	Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).
GO:0016779	nucleotidyltransferase activity	molecular_function	Catalysis of the transfer of a nucleotidyl group to a reactant.
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	molecular_function	Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).
GO:0016781	phosphotransferase activity, paired acceptors	molecular_function	Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.
GO:0016782	transferase activity, transferring sulphur-containing groups	molecular_function	Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).
GO:0016783	sulfurtransferase activity	molecular_function	Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
GO:0016784	3-mercaptopyruvate sulfurtransferase activity	molecular_function	Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
GO:0016785	selenotransferase activity	molecular_function	Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).
GO:0016787	hydrolase activity	molecular_function	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	molecular_function	Catalysis of the hydrolysis of any ester bond.
GO:0016790	thiolester hydrolase activity	molecular_function	Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
GO:0016791	phosphatase activity	molecular_function	Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0016793	triphosphoric monoester hydrolase activity	molecular_function	Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.
GO:0016794	diphosphoric monoester hydrolase activity	molecular_function	Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.
GO:0016795	phosphoric triester hydrolase activity	molecular_function	Catalysis of the hydrolysis of a phosphoric triester.
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
GO:0016797	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
GO:0016798	hydrolase activity, acting on glycosyl bonds	molecular_function	Catalysis of the hydrolysis of any glycosyl bond.
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	molecular_function	Catalysis of the hydrolysis of any N-glycosyl bond.
GO:0016801	hydrolase activity, acting on ether bonds	molecular_function	Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.
GO:0016802	trialkylsulfonium hydrolase activity	molecular_function	Catalysis of the hydrolysis of a thioether bond, -S-.
GO:0016803	ether hydrolase activity	molecular_function	Catalysis of the hydrolysis of an ether bond, -O-.
GO:0016805	dipeptidase activity	molecular_function	Catalysis of the hydrolysis of a dipeptide.
GO:0016807	cysteine-type carboxypeptidase activity	molecular_function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	molecular_function	Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
GO:0016815	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.
GO:0016817	hydrolase activity, acting on acid anhydrides	molecular_function	Catalysis of the hydrolysis of any acid anhydride.
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	molecular_function	Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016819	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides	molecular_function	Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.
GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds	molecular_function	Catalysis of the hydrolysis of any acid carbon-carbon bond.
GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	molecular_function	Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.
GO:0016824	hydrolase activity, acting on acid halide bonds	molecular_function	Catalysis of the hydrolysis of any acid halide bond.
GO:0016825	hydrolase activity, acting on acid phosphorus-nitrogen bonds	molecular_function	Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond.
GO:0016826	hydrolase activity, acting on acid sulfur-nitrogen bonds	molecular_function	Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.
GO:0016827	hydrolase activity, acting on acid carbon-phosphorus bonds	molecular_function	Catalysis of the hydrolysis of any acid carbon-phosphorus bond.
GO:0016828	hydrolase activity, acting on acid sulfur-sulfur bonds	molecular_function	Catalysis of the hydrolysis of any acid sulfur-sulfur bond.
GO:0016829	lyase activity	molecular_function	Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0016830	carbon-carbon lyase activity	molecular_function	Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0016831	carboxy-lyase activity	molecular_function	Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
GO:0016832	aldehyde-lyase activity	molecular_function	Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
GO:0016833	oxo-acid-lyase activity	molecular_function	Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
GO:0016835	carbon-oxygen lyase activity	molecular_function	Catalysis of the breakage of a carbon-oxygen bond.
GO:0016836	hydro-lyase activity	molecular_function	Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
GO:0016837	carbon-oxygen lyase activity, acting on polysaccharides	molecular_function	Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
GO:0016838	carbon-oxygen lyase activity, acting on phosphates	molecular_function	Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
GO:0016840	carbon-nitrogen lyase activity	molecular_function	Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
GO:0016841	ammonia-lyase activity	molecular_function	Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
GO:0016842	amidine-lyase activity	molecular_function	Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.
GO:0016843	amine-lyase activity	molecular_function	Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
GO:0016844	strictosidine synthase activity	molecular_function	Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = secologanin + tryptamine.
GO:0016846	carbon-sulfur lyase activity	molecular_function	Catalysis of the elimination of hydrogen sulfide or substituted H2S.
GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H+.
GO:0016848	carbon-halide lyase activity	molecular_function	Catalysis of the breakage of a bond between carbon and any halogen atom.
GO:0016849	phosphorus-oxygen lyase activity	molecular_function	Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0016851	magnesium chelatase activity	molecular_function	Catalysis of the reaction: ATP + H2O + Mg2+ + protoporphyrin IX = ADP + 3 H+ + Mg-protoporphyrin IX + phosphate.
GO:0016852	sirohydrochlorin cobaltochelatase activity	molecular_function	Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
GO:0016853	isomerase activity	molecular_function	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0016854	racemase and epimerase activity	molecular_function	Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	molecular_function	Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.
GO:0016856	racemase and epimerase activity, acting on hydroxy acids and derivatives	molecular_function	Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	molecular_function	Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.
GO:0016859	cis-trans isomerase activity	molecular_function	Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
GO:0016860	intramolecular oxidoreductase activity	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.
GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.
GO:0016862	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.
GO:0016866	intramolecular transferase activity	molecular_function	Catalysis of the transfer of a functional group from one position to another within a single molecule.
GO:0016867	intramolecular transferase activity, transferring acyl groups	molecular_function	Catalysis of the transfer of an acyl group from one position to another within a single molecule.
GO:0016868	intramolecular transferase activity, phosphotransferases	molecular_function	Catalysis of the transfer of a phosphate group from one position to another within a single molecule.
GO:0016869	intramolecular transferase activity, transferring amino groups	molecular_function	Catalysis of the transfer of an amino group from one position to another within a single molecule.
GO:0016871	cycloartenol synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.
GO:0016872	intramolecular lyase activity	molecular_function	The catalysis of certain rearrangements of a molecule to break or form a ring.
GO:0016874	ligase activity	molecular_function	Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.
GO:0016875	ligase activity, forming carbon-oxygen bonds	molecular_function	Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016877	ligase activity, forming carbon-sulfur bonds	molecular_function	Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016878	acid-thiol ligase activity	molecular_function	Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016879	ligase activity, forming carbon-nitrogen bonds	molecular_function	Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016880	acid-ammonia (or amide) ligase activity	molecular_function	Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016881	acid-amino acid ligase activity	molecular_function	Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016882	cyclo-ligase activity	molecular_function	Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	molecular_function	Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.
GO:0016885	ligase activity, forming carbon-carbon bonds	molecular_function	Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016886	ligase activity, forming phosphoric ester bonds	molecular_function	Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016887	ATP hydrolysis activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base	molecular_function	Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0016892	RNA endonuclease activity, producing 3'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
GO:0016897	RNA exonuclease activity, producing 3'-phosphomonoesters	molecular_function	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
GO:0016898	oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.
GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.
GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule.
GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016905	myosin heavy chain kinase activity	molecular_function	Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.
GO:0016906	sterol 3-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.
GO:0016907	G protein-coupled acetylcholine receptor activity	molecular_function	Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0016913	follicle-stimulating hormone activity	molecular_function	The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.
GO:0016914	follicle-stimulating hormone complex	cellular_component	A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.
GO:0016917	GABA receptor activity	molecular_function	Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.
GO:0016918	retinal binding	molecular_function	Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.
GO:0016920	pyroglutamyl-peptidase activity	molecular_function	Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.
GO:0016922	nuclear receptor binding	molecular_function	Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand.
GO:0016925	protein sumoylation	biological_process	The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
GO:0016926	protein desumoylation	biological_process	The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
GO:0016929	deSUMOylase activity	molecular_function	An thiol-dependent isopeptidase activity that cleaves SUMO from a target protein to which it is conjugated.
GO:0016933	extracellularly glycine-gated ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
GO:0016934	extracellularly glycine-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
GO:0016935	glycine-gated chloride channel complex	cellular_component	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
GO:0016936	galactoside binding	molecular_function	Binding to a glycoside in which the sugar group is galactose.
GO:0016937	short-chain-acyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short chain fatty acid residue.
GO:0016938	kinesin I complex	cellular_component	A complex of two kinesin heavy chains and two kinesin light chains.
GO:0016939	kinesin II complex	cellular_component	A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.
GO:0016941	natriuretic peptide receptor activity	molecular_function	Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.
GO:0016942	insulin-like growth factor binding protein complex	cellular_component	A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.
GO:0016964	alpha-2 macroglobulin receptor activity	molecular_function	Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.
GO:0016966	nitric oxide reductase activity	molecular_function	Catalysis of the reaction: H2O + 2 ferricytochrome c + nitrous oxide = 2 H+ + 2 ferrocytochrome c + 2 nitric oxide.
GO:0016971	flavin-dependent sulfhydryl oxidase activity	molecular_function	Catalysis of the reaction: [protein]-dithiol + O2 = [protein]-disulfide + H2O2 using FAD as a cofactor, leading to formation of disulfide bridges in proteins.
GO:0016972	thiol oxidase activity	molecular_function	Catalysis of the reaction: 2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + 2 H2O2.
GO:0016973	poly(A)+ mRNA export from nucleus	biological_process	The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
GO:0016977	chitosanase activity	molecular_function	Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.
GO:0016979	lipoate-protein ligase activity	molecular_function	Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP.
GO:0016980	creatinase activity	molecular_function	Catalysis of the reaction: creatine + H2O = sarcosine + urea.
GO:0016984	ribulose-bisphosphate carboxylase activity	molecular_function	Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O.
GO:0016985	mannan endo-1,4-beta-mannosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.
GO:0016987	sigma factor activity	molecular_function	Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
GO:0016989	sigma factor antagonist activity	molecular_function	The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.
GO:0016990	arginine deiminase activity	molecular_function	Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.
GO:0016992	lipoate synthase activity	molecular_function	Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.
GO:0016993	precorrin-8X methylmutase activity	molecular_function	Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.
GO:0016994	precorrin-6A reductase activity	molecular_function	Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.
GO:0016995	cholesterol oxidase activity	molecular_function	Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.
GO:0016996	endo-alpha-(2,8)-sialidase activity	molecular_function	Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.
GO:0016997	alpha-sialidase activity	molecular_function	Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
GO:0016998	cell wall macromolecule catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.
GO:0016999	antibiotic metabolic process	biological_process	The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
GO:0017000	antibiotic biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
GO:0017001	antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
GO:0017002	activin receptor activity	molecular_function	Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.
GO:0017003	protein-heme linkage	biological_process	The covalent linkage of heme and a protein.
GO:0017004	cytochrome complex assembly	biological_process	The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
GO:0017005	3'-tyrosyl-DNA phosphodiesterase activity	molecular_function	Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
GO:0017006	protein-tetrapyrrole linkage	biological_process	The covalent linking of a tetrapyrrole to a protein.
GO:0017007	protein-bilin linkage	biological_process	The covalent linkage of bilin and a protein.
GO:0017008	protein-phycobiliviolin linkage	biological_process	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.
GO:0017009	protein-phycocyanobilin linkage	biological_process	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.
GO:0017010	protein-phycourobilin linkage	biological_process	The linkage of the chromophore phycourobilin to phycoerythrins.
GO:0017011	protein-phycoerythrobilin linkage	biological_process	The linkage of the chromophore phycoerythrobilin to phycoerythrins.
GO:0017012	protein-phytochromobilin linkage	biological_process	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.
GO:0017013	protein flavinylation	biological_process	The addition of a flavin group to a protein amino acid.
GO:0017014	protein nitrosylation	biological_process	The covalent addition of a nitric oxide group to an amino acid within a protein.
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	molecular_function	Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.
GO:0017018	myosin phosphatase activity	molecular_function	Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
GO:0017020	myosin phosphatase regulator activity	molecular_function	Binds to and modulates of the activity of myosin phosphatase.
GO:0017022	myosin binding	molecular_function	Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
GO:0017023	myosin phosphatase complex	cellular_component	An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. Composed of a PP1 catalytic subunit (PP1c/PPP1CB) and a myosin phosphatase targeting subunit (MYPT1/PPP1R12A).
GO:0017024	myosin I binding	molecular_function	Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.
GO:0017025	TBP-class protein binding	molecular_function	Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
GO:0017032	amino acid:potassium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).
GO:0017038	protein import	biological_process	The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
GO:0017040	N-acylsphingosine amidohydrolase activity	molecular_function	Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.
GO:0017041	galactosylgalactosylglucosylceramidase activity	molecular_function	Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose.
GO:0017042	glycosylceramidase activity	molecular_function	Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.
GO:0017044	melanocyte-stimulating hormone activity	molecular_function	The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.
GO:0017045	corticotropin-releasing hormone activity	molecular_function	The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.
GO:0017046	peptide hormone binding	molecular_function	Binding to a peptide with hormonal activity in animals.
GO:0017050	D-erythro-sphingosine kinase activity	molecular_function	Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.
GO:0017051	retinol dehydratase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.
GO:0017053	transcription repressor complex	cellular_component	A protein complex that possesses activity that prevents or downregulates transcription.
GO:0017054	negative cofactor 2 complex	cellular_component	A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.
GO:0017055	negative regulation of RNA polymerase II transcription preinitiation complex assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
GO:0017056	structural constituent of nuclear pore	molecular_function	The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.
GO:0017057	6-phosphogluconolactonase activity	molecular_function	Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+.
GO:0017058	FH1 domain binding	molecular_function	Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.
GO:0017059	serine C-palmitoyltransferase complex	cellular_component	An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.
GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
GO:0017061	S-methyl-5-thioadenosine phosphorylase activity	molecular_function	Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.
GO:0017062	respiratory chain complex III assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.
GO:0017064	fatty acid amide hydrolase activity	molecular_function	Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
GO:0017065	single-strand selective uracil DNA N-glycosylase activity	molecular_function	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
GO:0017067	tyrosine-ester sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H+.
GO:0017069	snRNA binding	molecular_function	Binding to a small nuclear RNA (snRNA).
GO:0017070	U6 snRNA binding	molecular_function	Binding to a U6 small nuclear RNA (U6 snRNA).
GO:0017071	intracellular cyclic nucleotide activated cation channel complex	cellular_component	A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.
GO:0017075	syntaxin-1 binding	molecular_function	Binding to a syntaxin-1 SNAP receptor.
GO:0017076	purine nucleotide binding	molecular_function	Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.
GO:0017077	oxidative phosphorylation uncoupler activity	molecular_function	Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
GO:0017080	sodium channel regulator activity	molecular_function	Binds to and modulates the activity of a sodium channel.
GO:0017081	chloride channel regulator activity	molecular_function	Binds to and modulates the activity of a chloride channel.
GO:0017083	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R.
GO:0017084	delta1-pyrroline-5-carboxylate synthetase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.
GO:0017085	response to insecticide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
GO:0017086	3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	cellular_component	A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate.
GO:0017087	mitochondrial processing peptidase complex	cellular_component	A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
GO:0017089	glycolipid transfer activity	molecular_function	Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.
GO:0017090	meprin A complex	cellular_component	A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
GO:0017095	heparan sulfate 6-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.
GO:0017096	acetylserotonin O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
GO:0017098	sulfonylurea receptor binding	molecular_function	Binding to a sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.
GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	cellular_component	A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
GO:0017102	methionyl glutamyl tRNA synthetase complex	cellular_component	A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.
GO:0017103	UTP:galactose-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.
GO:0017105	acyl-CoA delta11-(Z)-desaturase activity	molecular_function	Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11Z)-delta-11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.
GO:0017108	5'-flap endonuclease activity	molecular_function	Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.
GO:0017109	glutamate-cysteine ligase complex	cellular_component	An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.
GO:0017110	nucleoside diphosphate phosphatase activity	molecular_function	Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate.
GO:0017111	ribonucleoside triphosphate phosphatase activity	molecular_function	Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0017113	dihydropyrimidine dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.
GO:0017116	single-stranded DNA helicase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.
GO:0017117	single-stranded DNA-dependent ATP-dependent DNA helicase complex	cellular_component	A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.
GO:0017118	lipoyltransferase activity	molecular_function	Catalysis of the reaction: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] = (R)-N6-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H+.
GO:0017119	Golgi transport complex	cellular_component	A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8.
GO:0017121	plasma membrane phospholipid scrambling	biological_process	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).
GO:0017122	protein N-acetylglucosaminyltransferase complex	cellular_component	A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits.
GO:0017124	SH3 domain binding	molecular_function	Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
GO:0017125	deoxycytidyl transferase activity	molecular_function	Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.
GO:0017126	nucleologenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.
GO:0017128	phospholipid scramblase activity	molecular_function	Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.
GO:0017129	triglyceride binding	molecular_function	Binding to a triester of glycerol.
GO:0017130	poly(C) RNA binding	molecular_function	Binding to a sequence of cytosine residues in an RNA molecule.
GO:0017131	uridine-rich cytoplasmic polyadenylylation element binding	molecular_function	Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.
GO:0017133	mitochondrial electron transfer flavoprotein complex	cellular_component	A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.
GO:0017134	fibroblast growth factor binding	molecular_function	Binding to a fibroblast growth factor.
GO:0017136	NAD-dependent histone deacetylase activity	molecular_function	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.
GO:0017143	insecticide metabolic process	biological_process	The chemical reactions and pathways involving insecticides, chemicals used to kill insects.
GO:0017145	stem cell division	biological_process	The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
GO:0017146	NMDA selective glutamate receptor complex	cellular_component	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
GO:0017147	Wnt-protein binding	molecular_function	Binding to a Wnt-protein, a secreted growth factor involved in signaling.
GO:0017148	negative regulation of translation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0017150	tRNA dihydrouridine synthase activity	molecular_function	Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.
GO:0017151	DEAD/H-box RNA helicase binding	molecular_function	Binding to a DEAD/H-box RNA helicase.
GO:0017153	sodium:dicarboxylate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).
GO:0017154	semaphorin receptor activity	molecular_function	Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0017156	calcium-ion regulated exocytosis	biological_process	The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
GO:0017157	regulation of exocytosis	biological_process	Any process that modulates the frequency, rate or extent of exocytosis.
GO:0017158	regulation of calcium ion-dependent exocytosis	biological_process	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.
GO:0017159	pantetheine hydrolase activity	molecular_function	Catalysis of the reaction: (R)-pantetheine + H2O = (R)-pantothenate + cysteamine.
GO:0017161	inositol-1,3,4-trisphosphate 4-phosphatase activity	molecular_function	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.
GO:0017162	aryl hydrocarbon receptor binding	molecular_function	Binding to an aryl hydrocarbon receptor.
GO:0017166	vinculin binding	molecular_function	Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
GO:0017168	5-oxoprolinase (ATP-hydrolyzing) activity	molecular_function	Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + 2 H+ + phosphate.
GO:0017169	CDP-alcohol phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.
GO:0017171	serine hydrolase activity	molecular_function	Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0017172	cysteine dioxygenase activity	molecular_function	Catalysis of the reaction: L-cysteine + O2 = 3-sulfino-L-alanine + H+.
GO:0017174	glycine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.
GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.
GO:0017177	glucosidase II complex	cellular_component	A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.
GO:0017178	diphthine-ammonia ligase activity	molecular_function	Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.
GO:0017183	protein histidyl modification to diphthamide	biological_process	The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
GO:0017185	peptidyl-lysine hydroxylation	biological_process	The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	biological_process	The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.
GO:0017187	peptidyl-glutamic acid carboxylation	biological_process	The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.
GO:0017188	aspartate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H+.
GO:0017189	N-terminal peptidyl-alanine acetylation	biological_process	The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.
GO:0017190	N-terminal peptidyl-aspartic acid acetylation	biological_process	The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.
GO:0017192	N-terminal peptidyl-glutamine acetylation	biological_process	The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.
GO:0017193	N-terminal peptidyl-glycine acetylation	biological_process	The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.
GO:0017194	N-terminal peptidyl-isoleucine acetylation	biological_process	The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.
GO:0017195	N-terminal peptidyl-lysine N2-acetylation	biological_process	The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.
GO:0017196	N-terminal peptidyl-methionine acetylation	biological_process	The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.
GO:0017197	N-terminal peptidyl-proline acetylation	biological_process	The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.
GO:0017198	N-terminal peptidyl-serine acetylation	biological_process	The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.
GO:0017199	N-terminal peptidyl-threonine acetylation	biological_process	The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.
GO:0018000	N-terminal peptidyl-tyrosine acetylation	biological_process	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.
GO:0018001	N-terminal peptidyl-valine acetylation	biological_process	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.
GO:0018002	N-terminal peptidyl-glutamic acid acetylation	biological_process	The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.
GO:0018003	peptidyl-lysine N6-acetylation	biological_process	The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.
GO:0018004	N-terminal protein formylation	biological_process	The formylation of the N-terminal amino acid of proteins.
GO:0018005	N-terminal peptidyl-glycine N-formylation	biological_process	The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.
GO:0018006	N-terminal protein amino acid glucuronylation	biological_process	The glucuronylation of the N-terminal amino acid of proteins.
GO:0018007	N-terminal peptidyl-glycine N-glucuronylation	biological_process	The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.
GO:0018008	N-terminal peptidyl-glycine N-myristoylation	biological_process	The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	biological_process	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.
GO:0018011	N-terminal peptidyl-alanine methylation	biological_process	The methylation of the N-terminal alanine of proteins.
GO:0018012	N-terminal peptidyl-alanine trimethylation	biological_process	The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.
GO:0018013	N-terminal peptidyl-glycine methylation	biological_process	The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
GO:0018014	N-terminal peptidyl-methionine methylation	biological_process	The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.
GO:0018015	N-terminal peptidyl-phenylalanine methylation	biological_process	The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.
GO:0018016	N-terminal peptidyl-proline dimethylation	biological_process	The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
GO:0018019	N-terminal peptidyl-glutamine methylation	biological_process	The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.
GO:0018020	peptidyl-glutamic acid methylation	biological_process	The addition of a methyl group to a glutamic acid residue in a protein.
GO:0018021	peptidyl-histidine methylation	biological_process	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).
GO:0018022	peptidyl-lysine methylation	biological_process	The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
GO:0018023	peptidyl-lysine trimethylation	biological_process	The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
GO:0018025	calmodulin-lysine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.
GO:0018026	peptidyl-lysine monomethylation	biological_process	The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
GO:0018027	peptidyl-lysine dimethylation	biological_process	The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.
GO:0018028	peptidyl-lysine myristoylation	biological_process	The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.
GO:0018029	peptidyl-lysine palmitoylation	biological_process	The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.
GO:0018030	peptidyl-lysine N6-myristoyltransferase activity	molecular_function	Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.
GO:0018031	peptidyl-lysine N6-palmitoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.
GO:0018032	protein amidation	biological_process	Addition of an amide group from a glycine to a protein amino acid.
GO:0018057	peptidyl-lysine oxidation	biological_process	The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.
GO:0018058	N-terminal protein amino acid deamination, from amino carbon	biological_process	The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.
GO:0018059	N-terminal peptidyl-serine deamination	biological_process	The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
GO:0018060	N-terminal peptidyl-cysteine deamination	biological_process	The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
GO:0018061	peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine	biological_process	The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.
GO:0018062	peptidyl-tryptophan succinylation	biological_process	The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.
GO:0018063	cytochrome c-heme linkage	biological_process	The linkage of cytochromes and other heme proteins to heme.
GO:0018064	protein-L-histidine N-tele-methyltransferase activity	molecular_function	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.
GO:0018067	peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	biological_process	The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA).
GO:0018068	peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine	biological_process	The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases.
GO:0018069	peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone	biological_process	The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.
GO:0018070	peptidyl-serine phosphopantetheinylation	biological_process	The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.
GO:0018071	NAD(P)-cysteine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine.
GO:0018072	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid	biological_process	The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.
GO:0018076	N-terminal peptidyl-lysine acetylation	biological_process	The acetylation of the N-terminal lysine of proteins.
GO:0018081	peptide cross-linking via lanthionine or 3-methyl-lanthionine	biological_process	The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.
GO:0018082	peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine	biological_process	The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.
GO:0018083	peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine	biological_process	The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.
GO:0018084	peptidyl-lactic acid biosynthetic process from peptidyl-serine	biological_process	The modification of N-terminal peptidyl-serine to lactic acid.
GO:0018085	peptidyl-L-amino acid racemization	biological_process	The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.
GO:0018094	protein polyglycylation	biological_process	The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.
GO:0018095	protein polyglutamylation	biological_process	The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
GO:0018096	peptide cross-linking via S-(2-aminovinyl)-D-cysteine	biological_process	The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine.
GO:0018102	peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine	biological_process	The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.
GO:0018103	protein C-linked glycosylation	biological_process	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.
GO:0018104	peptidoglycan-protein cross-linking	biological_process	The process of covalently linking peptidoglycan (murein) to proteins.
GO:0018105	peptidyl-serine phosphorylation	biological_process	The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
GO:0018106	peptidyl-histidine phosphorylation	biological_process	The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).
GO:0018107	peptidyl-threonine phosphorylation	biological_process	The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
GO:0018108	peptidyl-tyrosine phosphorylation	biological_process	The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
GO:0018109	peptidyl-arginine phosphorylation	biological_process	The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.
GO:0018111	methionine racemase activity	molecular_function	Catalysis of the reaction: L-methionine = D-methionine.
GO:0018112	proline racemase activity	molecular_function	Catalysis of the reaction: L-proline = D-proline.
GO:0018113	lysine racemase activity	molecular_function	Catalysis of the reaction: L-lysine = D-lysine.
GO:0018114	threonine racemase activity	molecular_function	Catalysis of the reaction: L-threonine = D-threonine.
GO:0018115	peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.
GO:0018116	peptidyl-lysine adenylylation	biological_process	The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine.
GO:0018117	protein adenylylation	biological_process	The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.
GO:0018119	peptidyl-cysteine S-nitrosylation	biological_process	The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.
GO:0018121	NAD(P)-asparagine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine.
GO:0018124	peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone	biological_process	The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.
GO:0018125	peptidyl-cysteine methylation	biological_process	The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.
GO:0018126	protein hydroxylation	biological_process	The addition of a hydroxy group to a protein amino acid.
GO:0018127	NAD(P)-serine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine.
GO:0018129	peptidyl-oxazoline dehydrogenase activity	molecular_function	Catalysis of the reduction of a peptide-linked oxazoline to oxazole.
GO:0018130	heterocycle biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0018131	oxazole or thiazole biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.
GO:0018132	peptide cross-linking via L-cysteine oxazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018133	peptide cross-linking via L-cysteine oxazolinecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.
GO:0018134	peptide cross-linking via glycine oxazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018136	peptidyl-thiazoline dehydrogenase activity	molecular_function	Catalysis of the reduction of a peptide-linked thiazoline to thiazole.
GO:0018137	peptide cross-linking via glycine thiazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018138	peptide cross-linking via L-serine thiazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018139	peptide cross-linking via L-phenylalanine thiazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018140	peptide cross-linking via L-cysteine thiazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018141	peptide cross-linking via L-lysine thiazolecarboxylic acid	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018142	protein-DNA covalent cross-linking	biological_process	The formation of a covalent cross-link between DNA and a protein.
GO:0018143	nucleic acid-protein covalent cross-linking	biological_process	The formation of a covalent cross-link between a nucleic acid and a protein.
GO:0018144	RNA-protein covalent cross-linking	biological_process	The formation of a covalent cross-link between RNA and a protein.
GO:0018145	protein-DNA covalent cross-linking via peptidyl-serine	biological_process	The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.
GO:0018146	keratan sulfate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
GO:0018147	molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)	biological_process	The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).
GO:0018148	RNA-protein covalent cross-linking via peptidyl-tyrosine	biological_process	The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.
GO:0018149	peptide cross-linking	biological_process	The formation of a covalent cross-link between or within protein chains.
GO:0018150	peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine	biological_process	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link.
GO:0018151	peptide cross-linking via L-histidyl-L-tyrosine	biological_process	The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link.
GO:0018152	peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine	biological_process	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link.
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	biological_process	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.
GO:0018154	peptide cross-linking via (2R,6R)-lanthionine	biological_process	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).
GO:0018155	peptide cross-linking via sn-(2S,6R)-lanthionine	biological_process	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).
GO:0018156	peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine	biological_process	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).
GO:0018157	peptide cross-linking via an oxazole or thiazole	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
GO:0018158	protein oxidation	biological_process	The modification of a protein amino acid by oxidation.
GO:0018159	peptidyl-methionine oxidation	biological_process	The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.
GO:0018160	peptidyl-pyrromethane cofactor linkage	biological_process	The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.
GO:0018161	dipyrrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.
GO:0018162	peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine	biological_process	The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.
GO:0018163	protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine	biological_process	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.
GO:0018164	protein-DNA covalent cross-linking via peptidyl-threonine	biological_process	The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.
GO:0018165	peptidyl-tyrosine uridylylation	biological_process	The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.
GO:0018167	protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine	biological_process	The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.
GO:0018168	protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine	biological_process	The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.
GO:0018169	ribosomal S6-glutamic acid ligase activity	molecular_function	Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.
GO:0018171	peptidyl-cysteine oxidation	biological_process	The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.
GO:0018172	peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	biological_process	The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine.
GO:0018173	peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine	biological_process	The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.
GO:0018174	protein-heme P460 linkage	biological_process	The linkage of protein to heme P460.
GO:0018175	protein nucleotidylation	biological_process	The addition of a nucleotide to a protein amino acid.
GO:0018177	protein uridylylation	biological_process	The addition of phospho-uridine to a protein amino acid.
GO:0018178	peptidyl-threonine adenylylation	biological_process	The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine.
GO:0018180	protein desulfurization	biological_process	The removal of a sulfur group from a protein amino acid.
GO:0018182	protein-heme linkage via 3'-L-histidine	biological_process	The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).
GO:0018184	protein polyamination	biological_process	The modification of a protein amino acid by polyamination.
GO:0018185	poly-N-methyl-propylamination	biological_process	The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.
GO:0018186	peroxidase-heme linkage	biological_process	The covalent linkage of heme to peroxidase.
GO:0018187	molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide	biological_process	The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.
GO:0018188	peptidyl-proline di-hydroxylation	biological_process	The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.
GO:0018189	pyrroloquinoline quinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.
GO:0018190	protein octanoylation	biological_process	The modification of a protein amino acid by formation of an ester or amide with octanoic acid.
GO:0018191	peptidyl-serine octanoylation	biological_process	The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.
GO:0018193	peptidyl-amino acid modification	biological_process	The alteration of an amino acid residue in a peptide.
GO:0018194	peptidyl-alanine modification	biological_process	The modification of peptidyl-alanine.
GO:0018195	peptidyl-arginine modification	biological_process	The modification of peptidyl-arginine.
GO:0018197	peptidyl-aspartic acid modification	biological_process	The modification of peptidyl-aspartic acid.
GO:0018198	peptidyl-cysteine modification	biological_process	The modification of peptidyl-cysteine.
GO:0018199	peptidyl-glutamine modification	biological_process	The modification of peptidyl-glutamine.
GO:0018200	peptidyl-glutamic acid modification	biological_process	The modification of peptidyl-glutamic acid.
GO:0018201	peptidyl-glycine modification	biological_process	The modification of peptidyl-glycine.
GO:0018202	peptidyl-histidine modification	biological_process	The modification of peptidyl-histidine.
GO:0018203	peptidyl-isoleucine modification	biological_process	The modification of peptidyl-isoleucine.
GO:0018204	peptidyl-leucine modification	biological_process	The modification of peptidyl-leucine.
GO:0018205	peptidyl-lysine modification	biological_process	The modification of peptidyl-lysine.
GO:0018206	peptidyl-methionine modification	biological_process	The modification of peptidyl-methionine.
GO:0018207	peptidyl-phenylalanine modification	biological_process	The modification of peptidyl-phenylalanine.
GO:0018208	peptidyl-proline modification	biological_process	The modification of peptidyl-proline.
GO:0018209	peptidyl-serine modification	biological_process	The modification of peptidyl-serine.
GO:0018210	peptidyl-threonine modification	biological_process	The modification of peptidyl-threonine.
GO:0018211	peptidyl-tryptophan modification	biological_process	The chemical alteration of a tryptophan residue in a peptide.
GO:0018212	peptidyl-tyrosine modification	biological_process	The modification of peptidyl-tyrosine.
GO:0018213	peptidyl-valine modification	biological_process	The modification of peptidyl-valine.
GO:0018214	protein carboxylation	biological_process	The addition of a carboxy group to a protein amino acid.
GO:0018215	protein phosphopantetheinylation	biological_process	The modification of a protein amino acid by phosphopantetheinylation.
GO:0018216	peptidyl-arginine methylation	biological_process	The addition of a methyl group to an arginine residue in a protein.
GO:0018217	peptidyl-aspartic acid phosphorylation	biological_process	The phosphorylation of peptidyl-aspartic acid.
GO:0018218	peptidyl-cysteine phosphorylation	biological_process	The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.
GO:0018219	peptidyl-cysteine S-acetylation	biological_process	The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.
GO:0018220	peptidyl-threonine palmitoylation	biological_process	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.
GO:0018221	peptidyl-serine palmitoylation	biological_process	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.
GO:0018226	peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.
GO:0018227	peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.
GO:0018228	peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.
GO:0018230	peptidyl-L-cysteine S-palmitoylation	biological_process	The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids.
GO:0018232	peptide cross-linking via S-(L-isoglutamyl)-L-cysteine	biological_process	The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.
GO:0018233	peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine	biological_process	The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link.
GO:0018234	peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine	biological_process	The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.
GO:0018235	peptidyl-lysine carboxylation	biological_process	The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.
GO:0018237	urease activator activity	molecular_function	Increases the activity of urease by promoting the incorporation of nickel into the active site.
GO:0018238	peptidyl-lysine carboxyethylation	biological_process	The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.
GO:0018240	protein S-linked glycosylation via cysteine	biological_process	The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.
GO:0018241	protein O-linked glycosylation via hydroxylysine	biological_process	The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.
GO:0018242	protein O-linked glycosylation via serine	biological_process	The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.
GO:0018243	protein O-linked glycosylation via threonine	biological_process	The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.
GO:0018244	protein N-linked glycosylation via tryptophan	biological_process	The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.
GO:0018245	protein O-linked glycosylation via tyrosine	biological_process	The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.
GO:0018246	protein-coenzyme A linkage	biological_process	The formation of a linkage between a protein amino acid and coenzyme A.
GO:0018247	protein-phosphoribosyl dephospho-coenzyme A linkage	biological_process	The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.
GO:0018249	protein dehydration	biological_process	The removal of a water group from a protein amino acid.
GO:0018250	peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine	biological_process	The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.
GO:0018251	peptidyl-tyrosine dehydrogenation	biological_process	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.
GO:0018253	peptide cross-linking via 5-imidazolinone glycine	biological_process	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.
GO:0018254	peptidyl-tyrosine adenylylation	biological_process	The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine.
GO:0018256	protein formylation	biological_process	The addition of a formyl group to a protein amino acid.
GO:0018257	peptidyl-lysine formylation	biological_process	The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.
GO:0018258	protein O-linked glycosylation via hydroxyproline	biological_process	The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.
GO:0018259	RNA-protein covalent cross-linking via peptidyl-serine	biological_process	The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.
GO:0018260	protein guanylylation	biological_process	The addition of phospho-guanosine to a protein amino acid.
GO:0018261	peptidyl-lysine guanylylation	biological_process	The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.
GO:0018262	isopeptide cross-linking	biological_process	The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.
GO:0018265	GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018266	GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018267	GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018268	GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018269	GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018270	GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018271	biotin-protein ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.
GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	biological_process	The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.
GO:0018274	peptide cross-linking via L-lysinoalanine	biological_process	The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.
GO:0018275	N-terminal peptidyl-cysteine acetylation	biological_process	The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.
GO:0018277	protein deamination	biological_process	The removal of an amino group from a protein amino acid.
GO:0018278	N-terminal peptidyl-threonine deamination	biological_process	The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.
GO:0018279	protein N-linked glycosylation via asparagine	biological_process	The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.
GO:0018280	protein S-linked glycosylation	biological_process	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.
GO:0018281	GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine	biological_process	The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0018282	metal incorporation into metallo-sulfur cluster	biological_process	The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.
GO:0018283	iron incorporation into metallo-sulfur cluster	biological_process	The incorporation of iron into a metallo-sulfur cluster.
GO:0018284	iron incorporation into protein via tetrakis-L-cysteinyl iron	biological_process	The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).
GO:0018285	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide	biological_process	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.
GO:0018287	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide	biological_process	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.
GO:0018288	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.
GO:0018289	molybdenum incorporation into metallo-sulfur cluster	biological_process	The incorporation of molybdenum into a metallo-sulfur cluster.
GO:0018290	iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide	biological_process	The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.
GO:0018291	molybdenum incorporation into iron-sulfur cluster	biological_process	The incorporation of molybdenum into an iron-sulfur cluster.
GO:0018292	molybdenum incorporation via L-cysteinyl molybdopterin	biological_process	The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.
GO:0018293	protein-FAD linkage	biological_process	The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).
GO:0018294	protein-FAD linkage via S-(8alpha-FAD)-L-cysteine	biological_process	The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine.
GO:0018295	protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine	biological_process	The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.
GO:0018296	protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine	biological_process	The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine.
GO:0018297	protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine	biological_process	The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.
GO:0018299	iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide	biological_process	The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.
GO:0018301	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon	biological_process	The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.
GO:0018302	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.
GO:0018303	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.
GO:0018304	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.
GO:0018305	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.
GO:0018306	iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.
GO:0018313	peptide cross-linking via L-alanyl-5-imidazolinone glycine	biological_process	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.
GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex	biological_process	The incorporation of molybdenum into a molybdenum-molybdopterin complex.
GO:0018316	peptide cross-linking via L-cystine	biological_process	The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.
GO:0018317	protein C-linked glycosylation via tryptophan	biological_process	The glycosylation of a carbon atom of a peptidyl-tryptophan residue.
GO:0018321	protein glucuronylation	biological_process	The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.
GO:0018335	protein succinylation	biological_process	The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.
GO:0018336	peptidyl-tyrosine hydroxylation	biological_process	The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.
GO:0018339	peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid	biological_process	The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.
GO:0018340	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine	biological_process	The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine.
GO:0018341	peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine	biological_process	The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine.
GO:0018342	protein prenylation	biological_process	The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
GO:0018343	protein farnesylation	biological_process	The covalent attachment of a farnesyl group to a protein.
GO:0018344	protein geranylgeranylation	biological_process	The covalent attachment of a geranylgeranyl group to a protein.
GO:0018345	protein palmitoylation	biological_process	The covalent attachment of a palmitoyl group to a protein.
GO:0018352	protein-pyridoxal-5-phosphate linkage	biological_process	The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.
GO:0018353	protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine	biological_process	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.
GO:0018355	protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine	biological_process	The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.
GO:0018356	protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine	biological_process	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.
GO:0018357	protein-phycourobilin linkage via phycourobilin-bis-L-cysteine	biological_process	The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.
GO:0018358	protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine	biological_process	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.
GO:0018359	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine	biological_process	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.
GO:0018360	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine	biological_process	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine.
GO:0018361	peptidyl-glutamine 2-methylation	biological_process	The methylation of glutamine to form 2-methyl-L-glutamine.
GO:0018362	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester	biological_process	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.
GO:0018363	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium	biological_process	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.
GO:0018364	peptidyl-glutamine methylation	biological_process	The addition of a methyl group to a glutamine residue in a protein.
GO:0018365	protein-serine epimerase activity	molecular_function	Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.
GO:0018366	chiral amino acid racemization	biological_process	The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.
GO:0018377	protein myristoylation	biological_process	The covalent attachment of a myristoyl group to a protein.
GO:0018378	cytochrome c-heme linkage via heme-L-cysteine	biological_process	The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine.
GO:0018379	cytochrome c-heme linkage via heme-bis-L-cysteine	biological_process	The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.
GO:0018386	N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine	biological_process	The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.
GO:0018387	N-terminal peptidyl-amino acid deamination to pyruvic acid	biological_process	The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
GO:0018388	N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine	biological_process	The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.
GO:0018389	N-terminal peptidyl-valine deamination	biological_process	The deamination of the N-terminal valine residue of a protein to form isobutyrate.
GO:0018392	glycoprotein 3-alpha-L-fucosyltransferase activity	molecular_function	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H+.
GO:0018393	internal peptidyl-lysine acetylation	biological_process	The addition of an acetyl group to a non-terminal lysine residue in a protein.
GO:0018394	peptidyl-lysine acetylation	biological_process	The acetylation of peptidyl-lysine.
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	biological_process	The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.
GO:0018396	peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine	biological_process	The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.
GO:0018400	peptidyl-proline hydroxylation to 3-hydroxy-L-proline	biological_process	The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	biological_process	The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.
GO:0018402	protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	biological_process	Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
GO:0018403	protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	biological_process	Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
GO:0018404	protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	biological_process	Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
GO:0018405	protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine	biological_process	Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.
GO:0018406	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	biological_process	The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.
GO:0018410	C-terminal protein amino acid modification	biological_process	The alteration of the C-terminal amino acid residue in a protein.
GO:0018411	protein glucuronidation	biological_process	The modification of a protein by amino acid glucuronidation.
GO:0018412	protein O-glucuronidation	biological_process	The modification of a protein by glucuronidation on an amino acid oxygen atom.
GO:0018413	peptidyl-serine O-glucuronidation	biological_process	The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.
GO:0018414	nickel incorporation into metallo-sulfur cluster	biological_process	The incorporation of nickel into a metallo-sulfur cluster.
GO:0018415	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	biological_process	The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.
GO:0018416	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	biological_process	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.
GO:0018417	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	biological_process	The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.
GO:0018418	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	biological_process	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.
GO:0018419	protein catenane formation	biological_process	The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.
GO:0018421	UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity	molecular_function	Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.
GO:0018422	GDP-mannose:serine-protein mannose-1-phosphotransferase activity	molecular_function	Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.
GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
GO:0018425	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.
GO:0018426	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.
GO:0018427	copper incorporation into metallo-sulfur cluster	biological_process	The incorporation of copper into a metallo-sulfur cluster.
GO:0018428	copper incorporation into copper-sulfur cluster	biological_process	The incorporation of copper into a copper-sulfur cluster.
GO:0018429	copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide	biological_process	The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.
GO:0018441	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide	biological_process	The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.
GO:0018444	translation release factor complex	cellular_component	A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.
GO:0018445	prothoracicotrophic hormone activity	molecular_function	The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.
GO:0018446	pinocarveol dehydrogenase activity	molecular_function	Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.
GO:0018447	chloral hydrate dehydrogenase activity	molecular_function	Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.
GO:0018448	hydroxymethylmethylsilanediol oxidase activity	molecular_function	Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.
GO:0018449	1-phenylethanol dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.
GO:0018450	myrtenol dehydrogenase activity	molecular_function	Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.
GO:0018451	epoxide dehydrogenase activity	molecular_function	Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA.
GO:0018452	5-exo-hydroxycamphor dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.
GO:0018453	2-hydroxytetrahydrofuran dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone.
GO:0018454	acetoacetyl-CoA reductase activity	molecular_function	Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.
GO:0018456	aryl-alcohol dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.
GO:0018457	perillyl-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + perillyl alcohol = H+ + NADH + perillyl aldehyde.
GO:0018458	isopiperitenol dehydrogenase activity	molecular_function	Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD+ = (6R)-isoperitenone + H+ + NADH.
GO:0018459	carveol dehydrogenase activity	molecular_function	Catalysis of the reaction: (1S,5R)-carveol + NADP+ = (R)-carvone + H+ + NADPH.
GO:0018460	cyclohexanol dehydrogenase activity	molecular_function	Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.
GO:0018461	fluoren-9-ol dehydrogenase activity	molecular_function	Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.
GO:0018462	4-(hydroxymethyl)benzenesulfonate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + H+ + NADH.
GO:0018463	6-hydroxyhexanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + H+ + NADH.
GO:0018464	3-hydroxypimeloyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD+ = 3-oxopimelyl-CoA + H+ + NADH.
GO:0018465	vanillyl-alcohol oxidase activity	molecular_function	Catalysis of the reaction: O2 + vanillyl alcohol = H2O2 + vanillin.
GO:0018466	limonene-1,2-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.
GO:0018467	formaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: formaldehyde + H2O + NAD+ = formate + 2 H+ + NADH.
GO:0018469	myrtenal dehydrogenase activity	molecular_function	Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.
GO:0018470	4-hydroxybutaraldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.
GO:0018471	4-chlorobenzaldehyde oxidase activity	molecular_function	Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.
GO:0018472	1-hydroxy-2-naphthaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.
GO:0018473	cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.
GO:0018474	2-carboxybenzaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.
GO:0018475	trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	molecular_function	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.
GO:0018477	benzaldehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.
GO:0018478	malonate-semialdehyde dehydrogenase (acetylating) activity	molecular_function	Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+.
GO:0018479	benzaldehyde dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
GO:0018480	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.
GO:0018481	4-hydroxymuconic-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H2O + NAD+ = 2 H+ + maleylacetate + NADH.
GO:0018482	4-formylbenzenesulfonate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-formylbenzenesulfonate + H2O + NAD+ = 4-sulfobenzoate + 2 H+ + NADH.
GO:0018483	6-oxohexanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.
GO:0018484	4-hydroxybenzaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.
GO:0018485	salicylaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.
GO:0018486	2-butanone oxidase activity	molecular_function	Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate.
GO:0018487	vanillate O-demethylase (anaerobic) activity	molecular_function	Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.
GO:0018488	aryl-aldehyde oxidase activity	molecular_function	Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.
GO:0018489	vanillate monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD+.
GO:0018490	4-hydroxyphenylpyruvate oxidase activity	molecular_function	Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O2 = 2 (4-hydroxyphenyl)acetate + 2 CO2.
GO:0018491	2-oxobutyrate synthase activity	molecular_function	Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.
GO:0018492	carbon-monoxide dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.
GO:0018493	formylmethanofuran dehydrogenase activity	molecular_function	Catalysis of the reaction: N-formylmethanofuran + A + H2O + H+ = AH(2) + CO2 + methanofuran.
GO:0018494	carvone reductase activity	molecular_function	Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.
GO:0018495	2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.
GO:0018496	2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.
GO:0018497	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.
GO:0018498	2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.
GO:0018499	cis-2,3-dihydrodiol DDT dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.
GO:0018500	trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity	molecular_function	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.
GO:0018501	cis-chlorobenzene dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.
GO:0018502	2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.
GO:0018503	trans-1,2-dihydrodiolphenanthrene dehydrogenase activity	molecular_function	Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.
GO:0018504	cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.
GO:0018505	cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.
GO:0018506	maleylacetate reductase activity	molecular_function	Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.
GO:0018507	cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD+ = H+ + NADH + phenanthrene-3,4-diol.
GO:0018508	cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.
GO:0018509	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.
GO:0018510	phloroglucinol reductase activity	molecular_function	Catalysis of the reaction: dihydrophloroglucinol + NADP+ = H+ + NADPH + phloroglucinol.
GO:0018511	2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ = 2,3-dihydroxy-p-cumate + H+ + NADH.
GO:0018513	dibenzothiophene dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+ = 1,2-dihydroxydibenzothiophene + H+ + NADH.
GO:0018515	pimeloyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H+ + NADH.
GO:0018516	2,4-dichlorobenzoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP+ = 2,4-dichlorobenzoyl-CoA + NADPH.
GO:0018517	phthalate 4,5-cis-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + H+ + NADH.
GO:0018518	5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity	molecular_function	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H+ + NADH.
GO:0018519	cis-dihydroethylcatechol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD+ = 3-ethylcatechol + H+ + NADH.
GO:0018520	cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.
GO:0018521	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH.
GO:0018522	benzoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H2O + benzoyl-CoA + reduced ferredoxin.
GO:0018523	quinoline 2-oxidoreductase activity	molecular_function	Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.
GO:0018524	acetophenone carboxylase activity	molecular_function	Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.
GO:0018525	4-hydroxybenzoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.
GO:0018526	2-aminobenzoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.
GO:0018527	cyclohexylamine oxidase activity	molecular_function	Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide.
GO:0018528	iminodiacetate dehydrogenase activity	molecular_function	Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.
GO:0018529	nitrilotriacetate monooxygenase activity	molecular_function	Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.
GO:0018530	(R)-6-hydroxynicotine oxidase activity	molecular_function	Catalysis of the reaction: (R)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2.
GO:0018531	(S)-6-hydroxynicotine oxidase activity	molecular_function	Catalysis of the reaction: (S)-6-hydroxynicotine + H2O + O2 = 6-hydroxypseudooxynicotine + H2O2.
GO:0018532	5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity	molecular_function	Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.
GO:0018533	peptidyl-cysteine acetylation	biological_process	The acetylation of peptidyl-cysteine.
GO:0018534	nitrilotriacetate dehydrogenase activity	molecular_function	Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.
GO:0018535	nicotine dehydrogenase activity	molecular_function	Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.
GO:0018537	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H+ = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.
GO:0018538	epoxide carboxylase activity	molecular_function	Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.
GO:0018541	p-benzoquinone reductase (NADPH) activity	molecular_function	Catalysis of the reaction: 1,4-benzoquinone + H+ + NADPH = hydroquinone + NADP+.
GO:0018542	2,3-dihydroxy DDT 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
GO:0018543	4-amino-2-nitroso-6-nitrotoluene reductase activity	molecular_function	Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.
GO:0018544	4-carboxy-4'-sulfoazobenzene reductase activity	molecular_function	Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.
GO:0018545	NAD(P)H nitroreductase activity	molecular_function	Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.
GO:0018546	nitrobenzene nitroreductase activity	molecular_function	Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.
GO:0018547	nitroglycerin reductase activity	molecular_function	Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.
GO:0018548	pentaerythritol trinitrate reductase activity	molecular_function	Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.
GO:0018549	methanethiol oxidase activity	molecular_function	Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.
GO:0018550	tetrachloro-p-hydroquinone reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.
GO:0018551	dissimilatory sulfite reductase activity	molecular_function	Catalysis of the reactions: [DsrC protein]-disulfide + 2 A + 3 H2O + hydrogen sulfide = [DsrC protein]-dithiol + 2 AH2 + H+ + sulfite and [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O = [DsrC protein]-disulfide + 3 AH2 + 2 H+ + sulfite.
GO:0018553	3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.
GO:0018554	1,2-dihydroxynaphthalene dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.
GO:0018555	phenanthrene dioxygenase activity	molecular_function	Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.
GO:0018556	2,2',3-trihydroxybiphenyl dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).
GO:0018557	1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.
GO:0018558	5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity	molecular_function	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.
GO:0018559	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.
GO:0018560	protocatechuate 3,4-dioxygenase type II activity	molecular_function	Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate.
GO:0018561	2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.
GO:0018562	3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.
GO:0018563	2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.
GO:0018564	carbazole 1,9a-dioxygenase activity	molecular_function	Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol.
GO:0018565	dihydroxydibenzothiophene dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.
GO:0018566	1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.
GO:0018567	styrene dioxygenase activity	molecular_function	Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.
GO:0018568	3,4-dihydroxyphenanthrene dioxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.
GO:0018569	hydroquinone 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.
GO:0018570	p-cumate 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.
GO:0018571	2,3-dihydroxy-p-cumate dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.
GO:0018572	3,5-dichlorocatechol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate.
GO:0018573	2-aminophenol 1,6-dioxygenase activity	molecular_function	Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde.
GO:0018574	2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.
GO:0018575	chlorocatechol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.
GO:0018576	catechol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: catechol + O2 = cis,cis-muconate.
GO:0018577	catechol 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.
GO:0018578	protocatechuate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
GO:0018579	protocatechuate 4,5-dioxygenase activity	molecular_function	Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.
GO:0018580	nitronate monooxygenase activity	molecular_function	Catalysis of the reaction: ethylnitronate + O2 = acetaldehyde + nitrite.
GO:0018581	hydroxyquinol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.
GO:0018582	1-hydroxy-2-naphthoate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.
GO:0018583	biphenyl-2,3-diol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.
GO:0018584	2,4,5-trichlorophenoxyacetic acid oxygenase activity	molecular_function	Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.
GO:0018585	fluorene oxygenase activity	molecular_function	Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.
GO:0018586	mono-butyltin dioxygenase activity	molecular_function	Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin.
GO:0018588	tri-n-butyltin dioxygenase activity	molecular_function	Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin.
GO:0018589	di-n-butyltin dioxygenase activity	molecular_function	Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.
GO:0018590	methylsilanetriol hydroxylase activity	molecular_function	Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.
GO:0018591	methyl tertiary butyl ether 3-monooxygenase activity	molecular_function	Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde.
GO:0018592	4-nitrocatechol 4-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.
GO:0018593	4-chlorophenoxyacetate monooxygenase activity	molecular_function	Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol.
GO:0018594	tert-butanol 2-monooxygenase activity	molecular_function	Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol.
GO:0018595	alpha-pinene monooxygenase activity	molecular_function	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol.
GO:0018596	dimethylsilanediol hydroxylase activity	molecular_function	Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.
GO:0018597	ammonia monooxygenase activity	molecular_function	Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.
GO:0018598	hydroxymethylsilanetriol oxidase activity	molecular_function	Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol.
GO:0018599	2-hydroxyisobutyrate 3-monooxygenase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate.
GO:0018600	alpha-pinene dehydrogenase activity	molecular_function	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol.
GO:0018601	4-nitrophenol 2-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.
GO:0018602	2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity	molecular_function	Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.
GO:0018603	nitrobenzene 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.
GO:0018604	4-aminobenzoate 3,4-dioxygenase (deaminating) activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate.
GO:0018606	benzenesulfonate dioxygenase activity	molecular_function	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.
GO:0018607	1-indanone monooxygenase activity	molecular_function	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.
GO:0018608	1-indanone dioxygenase activity	molecular_function	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.
GO:0018609	chlorobenzene dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).
GO:0018610	dibenzofuran 4,4a-dioxygenase activity	molecular_function	Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.
GO:0018611	toluate dioxygenase activity	molecular_function	Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.
GO:0018612	dibenzothiophene dioxygenase activity	molecular_function	Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.
GO:0018613	9-fluorenone dioxygenase activity	molecular_function	Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.
GO:0018614	ethylbenzene dioxygenase activity	molecular_function	Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.
GO:0018615	2-indanone monooxygenase activity	molecular_function	Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone.
GO:0018616	trihydroxytoluene dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.
GO:0018617	4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity	molecular_function	Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol.
GO:0018618	anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity	molecular_function	Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.
GO:0018619	benzene 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: benzene + H+ + NADH + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+.
GO:0018620	phthalate 4,5-dioxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+.
GO:0018621	4-sulfobenzoate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 4-sulfobenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + sulfite.
GO:0018622	4-chlorophenylacetate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.
GO:0018623	benzoate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.
GO:0018624	toluene dioxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.
GO:0018625	naphthalene 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.
GO:0018626	2-chlorobenzoate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.
GO:0018627	2-aminobenzenesulfonate 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H+ + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD+ + NH4. 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.
GO:0018628	terephthalate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+.
GO:0018629	2-hydroxyquinoline 5,6-dioxygenase activity	molecular_function	Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.
GO:0018630	3,5-xylenol methylhydroxylase activity	molecular_function	Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.
GO:0018631	phenylacetate hydroxylase activity	molecular_function	Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate.
GO:0018632	4-nitrophenol 4-monooxygenase activity	molecular_function	Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.
GO:0018633	dimethyl sulfide monooxygenase activity	molecular_function	Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.
GO:0018634	alpha-pinene monooxygenase [NADH] activity	molecular_function	Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.
GO:0018635	(R)-limonene 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.
GO:0018636	phenanthrene 9,10-monooxygenase activity	molecular_function	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.
GO:0018637	1-hydroxy-2-naphthoate hydroxylase activity	molecular_function	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.
GO:0018638	toluene 4-monooxygenase activity	molecular_function	Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene.
GO:0018639	xylene monooxygenase activity	molecular_function	Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.
GO:0018640	dibenzothiophene monooxygenase activity	molecular_function	Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.
GO:0018641	6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	molecular_function	Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
GO:0018642	chlorophenol 4-monooxygenase activity	molecular_function	Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.
GO:0018643	carbon disulfide oxygenase activity	molecular_function	Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.
GO:0018644	toluene 2-monooxygenase activity	molecular_function	Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene.
GO:0018645	alkene monooxygenase activity	molecular_function	Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.
GO:0018646	1-hydroxy-2-oxolimonene 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.
GO:0018647	phenanthrene 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.
GO:0018648	methanesulfonate monooxygenase activity	molecular_function	Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.
GO:0018649	tetrahydrofuran hydroxylase activity	molecular_function	Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran.
GO:0018650	styrene monooxygenase activity	molecular_function	Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.
GO:0018651	toluene-4-sulfonate monooxygenase activity	molecular_function	Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene.
GO:0018652	toluene-sulfonate methyl-monooxygenase activity	molecular_function	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.
GO:0018653	3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	molecular_function	Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
GO:0018654	2-hydroxy-phenylacetate hydroxylase activity	molecular_function	Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate.
GO:0018655	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.
GO:0018656	phenanthrene 3,4-monooxygenase activity	molecular_function	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide.
GO:0018657	toluene 3-monooxygenase activity	molecular_function	Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene.
GO:0018658	salicylate 1-monooxygenase activity	molecular_function	Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.
GO:0018659	4-hydroxybenzoate 3-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.
GO:0018661	orcinol 2-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + orcinol = 2,3,5-trihydroxytoluene + H2O + NAD+.
GO:0018662	phenol 2-monooxygenase activity	molecular_function	Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.
GO:0018663	2,6-dihydroxypyridine 3-monooxygenase activity	molecular_function	Catalysis of the reaction: 2,6-dihydroxypyridine + H+ + NADH + O2 = 2,3,6-trihydroxypyridine + H2O + NAD+.
GO:0018664	benzoate 4-monooxygenase activity	molecular_function	Catalysis of the reaction: benzoate + H+ + NADPH + O2 = 4-hydroxybenzoate + H2O + NADP+.
GO:0018665	4-hydroxyphenylacetate 1-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.
GO:0018666	2,4-dichlorophenol 6-monooxygenase activity	molecular_function	Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.
GO:0018667	cyclohexanone monooxygenase activity	molecular_function	Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.
GO:0018668	3-hydroxybenzoate 4-monooxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.
GO:0018669	3-hydroxybenzoate 6-monooxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxybenzoate + H+ + NADH + O2 = 2,5-dihydroxybenzoate + H2O + NAD+.
GO:0018670	4-aminobenzoate 1-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.
GO:0018671	4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.
GO:0018672	anthranilate 3-monooxygenase (deaminating) activity	molecular_function	Catalysis of the reaction: anthranilate + 2 H+ + NADPH + O2 = 2,3-dihydroxybenzoate + NADP+ + NH4.
GO:0018673	anthraniloyl-CoA monooxygenase activity	molecular_function	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.
GO:0018674	(S)-limonene 3-monooxygenase activity	molecular_function	Catalysis of the reaction: (4S)-limonene + H+ + NADPH + O2 = (1S,6R)-isopiperitenol + H2O + NADP+.
GO:0018675	(S)-limonene 6-monooxygenase activity	molecular_function	Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O.
GO:0018676	(S)-limonene 7-monooxygenase activity	molecular_function	Catalysis of the reaction: (4S)-limonene + H+ + NADPH + O2 = (4S)-perillyl alcohol + H2O + NADP+.
GO:0018677	pentachlorophenol monooxygenase activity	molecular_function	Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.
GO:0018678	4-hydroxybenzoate 1-hydroxylase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.
GO:0018679	dibenzothiophene-5,5-dioxide monooxygenase activity	molecular_function	Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.
GO:0018680	deethylatrazine monooxygenase activity	molecular_function	Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.
GO:0018681	deisopropylatrazine monooxygenase activity	molecular_function	Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.
GO:0018682	atrazine N-dealkylase activity	molecular_function	Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.
GO:0018683	camphor 5-monooxygenase activity	molecular_function	Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.
GO:0018684	2,5-diketocamphane 1,2-monooxygenase	molecular_function	Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O.
GO:0018685	alkane 1-monooxygenase activity	molecular_function	Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
GO:0018686	6-hydroxy pseudo-oxynicotine monooxygenase activity	molecular_function	Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.
GO:0018687	biphenyl 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.
GO:0018688	DDT 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.
GO:0018689	naphthalene disulfonate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).
GO:0018690	4-methoxybenzoate monooxygenase (O-demethylating) activity	molecular_function	Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O2 = 4-hydroxybenzoate + A + formaldehyde + H2O.
GO:0018693	ethylbenzene hydroxylase activity	molecular_function	Catalysis of the reaction: A + ethylbenzene + H2O = (S)-1-phenylethanol + AH(2).
GO:0018694	p-cymene methyl hydroxylase activity	molecular_function	Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.
GO:0018695	4-cresol dehydrogenase (hydroxylating) activity	molecular_function	Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.
GO:0018697	carbonyl sulfide nitrogenase activity	molecular_function	Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.
GO:0018698	vinyl chloride reductive dehalogenase activity	molecular_function	Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.
GO:0018699	1,1,1-trichloroethane reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.
GO:0018700	2-chloro-N-isopropylacetanilide reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.
GO:0018701	2,5-dichlorohydroquinone reductive dehalogenase activity	molecular_function	Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).
GO:0018702	1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity	molecular_function	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
GO:0018703	2,4-dichlorophenoxyacetate dehalogenase activity	molecular_function	Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.
GO:0018705	1,2-dichloroethene reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.
GO:0018706	pyrogallol hydroxytransferase activity	molecular_function	Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.
GO:0018707	1-phenanthrol methyltransferase activity	molecular_function	Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.
GO:0018708	thiol S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.
GO:0018710	acetone carboxylase activity	molecular_function	Catalysis of the reaction: acetone + ATP + CO2 + 2 H2O = acetoacetate + AMP + 4 H+ + 2 phosphate.
GO:0018711	benzoyl acetate-CoA thiolase activity	molecular_function	Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA.
GO:0018712	3-hydroxybutyryl-CoA thiolase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.
GO:0018713	3-ketopimelyl-CoA thiolase activity	molecular_function	Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.
GO:0018715	9-phenanthrol UDP-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.
GO:0018716	1-phenanthrol glycosyltransferase activity	molecular_function	Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.
GO:0018717	9-phenanthrol glycosyltransferase activity	molecular_function	Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O.
GO:0018718	1,2-dihydroxy-phenanthrene glycosyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.
GO:0018719	6-aminohexanoate transaminase activity	molecular_function	Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate.
GO:0018720	phenol kinase activity	molecular_function	Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.
GO:0018721	trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity	molecular_function	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.
GO:0018722	1-phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.
GO:0018723	3-phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate.
GO:0018724	4-phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.
GO:0018725	trans-3,4-dihydrodiolphenanthrene sulfotransferase activity	molecular_function	Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.
GO:0018726	9-phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.
GO:0018727	2-phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.
GO:0018729	propionate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.
GO:0018730	glutaconate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.
GO:0018731	1-oxa-2-oxocycloheptane lactonase activity	molecular_function	Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.
GO:0018732	sulfolactone hydrolase activity	molecular_function	Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.
GO:0018733	3,4-dihydrocoumarin hydrolase activity	molecular_function	Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.
GO:0018734	butyrolactone hydrolase activity	molecular_function	Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.
GO:0018736	6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.
GO:0018737	2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.
GO:0018738	S-formylglutathione hydrolase activity	molecular_function	Catalysis of the reaction: S-formylglutathione + H2O = formate + glutathione + H+.
GO:0018739	4-hydroxybenzoyl-CoA thioesterase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H+.
GO:0018740	2'-hydroxybiphenyl-2-sulfinate desulfinase activity	molecular_function	Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H2O = biphenyl-2-ol + sulfite.
GO:0018741	linear primary-alkylsulfatase activity	molecular_function	Catalysis of the reaction: a primary linear alkyl sulfate ester + H2O =>a primary alcohol + H(+) + sulfate.
GO:0018742	epoxide hydrolase B activity	molecular_function	Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.
GO:0018743	phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity	molecular_function	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.
GO:0018744	limonene-1,2-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.
GO:0018745	epoxide hydrolase A activity	molecular_function	Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.
GO:0018746	phenanthrene-3,4-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.
GO:0018747	phenanthrene-1,2-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.
GO:0018748	iprodione amidohydrolase activity	molecular_function	Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate.
GO:0018749	(3,5-dichlorophenylurea)acetate amidohydrolase activity	molecular_function	Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.
GO:0018750	biuret amidohydrolase activity	molecular_function	Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.
GO:0018751	3,5-dichlorophenylcarboximide hydrolase activity	molecular_function	Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.
GO:0018752	epsilon-caprolactam lactamase activity	molecular_function	Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.
GO:0018753	cyanuric acid amidohydrolase activity	molecular_function	Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2.
GO:0018754	ammelide aminohydrolase activity	molecular_function	Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.
GO:0018755	2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity	molecular_function	Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.
GO:0018756	ammeline aminohydrolase activity	molecular_function	Catalysis of the reaction: ammeline + H2O = ammelide + NH3.
GO:0018757	deisopropylhydroxyatrazine aminohydrolase activity	molecular_function	Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine.
GO:0018758	2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity	molecular_function	Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.
GO:0018759	methenyltetrahydromethanopterin cyclohydrolase activity	molecular_function	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H+.
GO:0018760	thiocyanate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 2 H+ + thiocyanate = carbonyl sulfide + NH4.
GO:0018761	bromoxynil nitrilase activity	molecular_function	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.
GO:0018762	aliphatic nitrilase activity	molecular_function	Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.
GO:0018763	hydroxydechloroatrazine ethylaminohydrolase activity	molecular_function	Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.
GO:0018764	N-isopropylammelide isopropylaminohydrolase activity	molecular_function	Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.
GO:0018765	2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.
GO:0018766	dihydrophloroglucinol hydrolase activity	molecular_function	Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.
GO:0018767	2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.
GO:0018768	2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.
GO:0018769	2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.
GO:0018770	6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity	molecular_function	Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.
GO:0018771	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity	molecular_function	Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.
GO:0018772	trioxoheptanoate hydrolase activity	molecular_function	Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.
GO:0018773	acetylpyruvate hydrolase activity	molecular_function	Catalysis of the reaction: acetylpyruvate + H2O = acetate + H+ + pyruvate.
GO:0018774	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity	molecular_function	Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate.
GO:0018775	2-hydroxymuconate-semialdehyde hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.
GO:0018776	trans-chloroacrylic acid dehalogenase activity	molecular_function	Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde.
GO:0018777	1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity	molecular_function	Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).
GO:0018778	DL-2 haloacid dehalogenase activity	molecular_function	Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.
GO:0018780	dichloroacetate halidohydrolase activity	molecular_function	Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate.
GO:0018781	S-triazine hydrolase activity	molecular_function	Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.
GO:0018782	cis-chloroacrylic acid dehalogenase activity	molecular_function	Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde.
GO:0018783	deisopropyldeethylatrazine hydrolase activity	molecular_function	Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.
GO:0018784	(S)-2-haloacid dehalogenase activity	molecular_function	Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.
GO:0018785	haloacetate dehalogenase activity	molecular_function	Catalysis of the reaction: haloacetate + H2O = glycolate + halide.
GO:0018786	haloalkane dehalogenase activity	molecular_function	Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.
GO:0018787	4-chlorobenzoyl-CoA dehalogenase activity	molecular_function	Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.
GO:0018788	atrazine chlorohydrolase activity	molecular_function	Catalysis of the reaction: atrazine + H2O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H+.
GO:0018789	cyclamate sulfohydrolase activity	molecular_function	Catalysis of the reaction: cyclohexylsulfamate + H2O = cyclohexylamine + sulfate.
GO:0018791	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.
GO:0018792	bis(4-chlorophenyl)acetate decarboxylase activity	molecular_function	Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.
GO:0018793	3,5-dibromo-4-hydroxybenzoate decarboxylase activity	molecular_function	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.
GO:0018794	2-hydroxyisobutyrate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.
GO:0018795	2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.
GO:0018796	4,5-dihydroxyphthalate decarboxylase activity	molecular_function	Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.
GO:0018798	gallate decarboxylase activity	molecular_function	Catalysis of the reaction: gallate + H+ = CO2 + pyrogallol.
GO:0018799	4-hydroxybenzoate decarboxylase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + H+ = CO2 + phenol.
GO:0018800	5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity	molecular_function	Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.
GO:0018801	glutaconyl-CoA decarboxylase activity	molecular_function	Catalysis of the reaction: trans-glutaconyl-CoA + H+ = but-2-enoyl-CoA + CO2.
GO:0018802	2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity	molecular_function	Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.
GO:0018803	4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity	molecular_function	Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.
GO:0018805	benzylsuccinate synthase activity	molecular_function	Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.
GO:0018807	6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.
GO:0018808	trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity	molecular_function	Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.
GO:0018809	E-phenylitaconyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA.
GO:0018810	trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity	molecular_function	Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.
GO:0018811	cyclohex-1-ene-1-carboxyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.
GO:0018812	3-hydroxyacyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O.
GO:0018813	trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity	molecular_function	Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).
GO:0018814	phenylacetaldoxime dehydratase activity	molecular_function	Catalysis of the reaction: (trans)-phenylacetaldoxime = H2O + phenylacetonitrile.
GO:0018815	3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity	molecular_function	Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.
GO:0018816	2-hydroxyisobutyrate dehydratase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.
GO:0018817	2-oxo-hept-3-ene-1,7-dioate hydratase activity	molecular_function	Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.
GO:0018818	acetylene hydratase activity	molecular_function	Catalysis of the reaction: acetaldehyde = acetylene + H2O.
GO:0018819	lactoyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.
GO:0018820	cyanamide hydratase activity	molecular_function	Catalysis of the reaction: urea = cyanamide + H2O.
GO:0018822	nitrile hydratase activity	molecular_function	Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.
GO:0018823	cyclohexa-1,5-dienecarbonyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-enecarbonyl-CoA.
GO:0018824	(hydroxyamino)benzene mutase activity	molecular_function	Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol.
GO:0018825	triethanolamine lyase activity	molecular_function	Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.
GO:0018826	methionine gamma-lyase activity	molecular_function	Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.
GO:0018827	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	molecular_function	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.
GO:0018828	halohydrin hydrogen-halide-lyase A activity	molecular_function	Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.
GO:0018829	1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	molecular_function	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
GO:0018830	gamma-hexachlorocyclohexane dehydrochlorinase activity	molecular_function	Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.
GO:0018831	5-chloro-1,2,4-trihydroxybenzene dechlorinase activity	molecular_function	Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.
GO:0018832	halohydrin hydrogen-halide-lyase B activity	molecular_function	Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.
GO:0018833	DDT-dehydrochlorinase activity	molecular_function	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H+.
GO:0018834	dichloromethane dehalogenase activity	molecular_function	Catalysis of the reaction: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H+.
GO:0018835	carbon phosphorus lyase activity	molecular_function	Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).
GO:0018836	alkylmercury lyase activity	molecular_function	Catalysis of the reaction: an alkylmercury + H+ = an alkane + Hg2+.
GO:0018837	2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate.
GO:0018838	mandelate racemase activity	molecular_function	Catalysis of the reaction: (S)-mandelate = (R)-mandelate.
GO:0018839	cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity	molecular_function	Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.
GO:0018844	2-hydroxytetrahydrofuran isomerase activity	molecular_function	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde.
GO:0018845	2-hydroxychromene-2-carboxylate isomerase activity	molecular_function	Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.
GO:0018846	styrene-oxide isomerase activity	molecular_function	Catalysis of the reaction: styrene oxide = phenylacetaldehyde.
GO:0018847	alpha-pinene lyase activity	molecular_function	Catalysis of the reaction: alpha-pinene = limonene.
GO:0018848	pinocarveol isomerase activity	molecular_function	Catalysis of the reaction: pinocarveol = carveol.
GO:0018849	muconate cycloisomerase activity	molecular_function	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.
GO:0018850	chloromuconate cycloisomerase activity	molecular_function	Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.
GO:0018851	alpha-pinene-oxide decyclase activity	molecular_function	Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.
GO:0018852	dichloromuconate cycloisomerase activity	molecular_function	Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.
GO:0018854	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
GO:0018855	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.
GO:0018856	benzoyl acetate-CoA ligase activity	molecular_function	Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.
GO:0018857	2,4-dichlorobenzoate-CoA ligase activity	molecular_function	Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.
GO:0018858	benzoate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate.
GO:0018859	4-hydroxybenzoate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.
GO:0018860	anthranilate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.
GO:0018861	4-chlorobenzoate-CoA ligase activity	molecular_function	Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
GO:0018862	phenylphosphate carboxylase activity	molecular_function	Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate.
GO:0018863	phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity	molecular_function	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.
GO:0018864	acetylene metabolic process	biological_process	The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.
GO:0018865	acrylonitrile metabolic process	biological_process	The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.
GO:0018866	adamantanone metabolic process	biological_process	The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.
GO:0018867	alpha-pinene metabolic process	biological_process	The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.
GO:0018868	2-aminobenzenesulfonate metabolic process	biological_process	The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
GO:0018870	anaerobic 2-aminobenzoate metabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.
GO:0018871	1-aminocyclopropane-1-carboxylate metabolic process	biological_process	The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
GO:0018872	arsonoacetate metabolic process	biological_process	The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.
GO:0018873	atrazine metabolic process	biological_process	The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.
GO:0018874	benzoate metabolic process	biological_process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
GO:0018875	anaerobic benzoate metabolic process	biological_process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen.
GO:0018876	benzonitrile metabolic process	biological_process	The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.
GO:0018877	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	biological_process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.
GO:0018878	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	biological_process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen.
GO:0018879	biphenyl metabolic process	biological_process	The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
GO:0018880	4-chlorobiphenyl metabolic process	biological_process	The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.
GO:0018881	bromoxynil metabolic process	biological_process	The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.
GO:0018882	(+)-camphor metabolic process	biological_process	The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.
GO:0018883	caprolactam metabolic process	biological_process	The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation.
GO:0018884	carbazole metabolic process	biological_process	The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
GO:0018885	carbon tetrachloride metabolic process	biological_process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
GO:0018886	anaerobic carbon tetrachloride metabolic process	biological_process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.
GO:0018887	4-carboxy-4'-sulfoazobenzene metabolic process	biological_process	The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.
GO:0018888	3-chloroacrylic acid metabolic process	biological_process	The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.
GO:0018889	2-chloro-N-isopropylacetanilide metabolic process	biological_process	The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.
GO:0018890	cyanamide metabolic process	biological_process	The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.
GO:0018891	cyclohexanol metabolic process	biological_process	The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.
GO:0018892	cyclohexylsulfamate metabolic process	biological_process	The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.
GO:0018893	dibenzofuran metabolic process	biological_process	The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.
GO:0018894	dibenzo-p-dioxin metabolic process	biological_process	The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.
GO:0018895	dibenzothiophene metabolic process	biological_process	The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.
GO:0018896	dibenzothiophene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.
GO:0018897	dibenzothiophene desulfurization	biological_process	The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.
GO:0018898	2,4-dichlorobenzoate metabolic process	biological_process	The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
GO:0018899	1,2-dichloroethane metabolic process	biological_process	The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
GO:0018900	dichloromethane metabolic process	biological_process	The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.
GO:0018901	2,4-dichlorophenoxyacetic acid metabolic process	biological_process	The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
GO:0018903	1,3-dichloropropene metabolic process	biological_process	The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.
GO:0018904	ether metabolic process	biological_process	The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.
GO:0018905	dimethyl ether metabolic process	biological_process	The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.
GO:0018906	methyl tert-butyl ether metabolic process	biological_process	The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.
GO:0018907	dimethyl sulfoxide metabolic process	biological_process	The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.
GO:0018908	organosulfide cycle	biological_process	A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle.
GO:0018909	dodecyl sulfate metabolic process	biological_process	The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.
GO:0018910	benzene metabolic process	biological_process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.
GO:0018911	1,2,4-trichlorobenzene metabolic process	biological_process	The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.
GO:0018912	1,4-dichlorobenzene metabolic process	biological_process	The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs.
GO:0018913	anaerobic ethylbenzene metabolic process	biological_process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.
GO:0018914	chlorobenzene metabolic process	biological_process	The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.
GO:0018915	ethylbenzene metabolic process	biological_process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.
GO:0018916	nitrobenzene metabolic process	biological_process	The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.
GO:0018919	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	biological_process	The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.
GO:0018920	glyphosate metabolic process	biological_process	The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.
GO:0018921	3-hydroxybenzyl alcohol metabolic process	biological_process	The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.
GO:0018922	iprodione metabolic process	biological_process	The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).
GO:0018923	limonene metabolic process	biological_process	The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
GO:0018924	mandelate metabolic process	biological_process	The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
GO:0018925	m-cresol metabolic process	biological_process	The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.
GO:0018926	methanesulfonic acid metabolic process	biological_process	The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.
GO:0018928	methyl ethyl ketone metabolic process	biological_process	The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.
GO:0018929	methyl fluoride metabolic process	biological_process	The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils.
GO:0018930	3-methylquinoline metabolic process	biological_process	The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.
GO:0018933	nicotine metabolic process	biological_process	The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
GO:0018934	nitrilotriacetate metabolic process	biological_process	The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.
GO:0018935	aerobic nitrilotriacetate metabolic process	biological_process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.
GO:0018936	anaerobic nitrilotriacetate metabolic process	biological_process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.
GO:0018937	nitroglycerin metabolic process	biological_process	The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.
GO:0018938	2-nitropropane metabolic process	biological_process	The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.
GO:0018939	n-octane metabolic process	biological_process	The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.
GO:0018940	orcinol metabolic process	biological_process	The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.
GO:0018941	organomercury metabolic process	biological_process	The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom.
GO:0018942	organometal metabolic process	biological_process	The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.
GO:0018943	organotin metabolic process	biological_process	The chemical reactions and pathways involving organotin, an organic compound containing a tin atom.
GO:0018944	tri-n-butyltin metabolic process	biological_process	The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.
GO:0018945	organosilicon metabolic process	biological_process	The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon.
GO:0018946	aerobic organosilicon metabolic process	biological_process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.
GO:0018947	anaerobic organosilicon metabolic process	biological_process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.
GO:0018948	xylene metabolic process	biological_process	The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.
GO:0018949	m-xylene metabolic process	biological_process	The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
GO:0018950	o-xylene metabolic process	biological_process	The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
GO:0018951	p-xylene metabolic process	biological_process	The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
GO:0018952	parathion metabolic process	biological_process	The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.
GO:0018953	p-cymene metabolic process	biological_process	The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.
GO:0018954	pentaerythritol tetranitrate metabolic process	biological_process	The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.
GO:0018955	phenanthrene metabolic process	biological_process	The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.
GO:0018956	phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene	biological_process	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite.
GO:0018957	phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene	biological_process	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite.
GO:0018958	phenol-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
GO:0018959	aerobic phenol-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
GO:0018960	4-nitrophenol metabolic process	biological_process	The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
GO:0018961	pentachlorophenol metabolic process	biological_process	The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.
GO:0018962	3-phenylpropionate metabolic process	biological_process	The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins.
GO:0018963	phthalate metabolic process	biological_process	The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.
GO:0018964	propylene metabolic process	biological_process	The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.
GO:0018965	s-triazine compound metabolic process	biological_process	The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.
GO:0018966	styrene metabolic process	biological_process	The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.
GO:0018967	tetrachloroethylene metabolic process	biological_process	The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.
GO:0018968	tetrahydrofuran metabolic process	biological_process	The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.
GO:0018969	thiocyanate metabolic process	biological_process	The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.
GO:0018970	toluene metabolic process	biological_process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.
GO:0018971	anaerobic toluene metabolic process	biological_process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.
GO:0018972	toluene-4-sulfonate metabolic process	biological_process	The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.
GO:0018973	trinitrotoluene metabolic process	biological_process	The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.
GO:0018974	2,4,6-trinitrotoluene metabolic process	biological_process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.
GO:0018975	anaerobic 2,4,6-trinitrotoluene metabolic process	biological_process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.
GO:0018976	1,2,3-tribromopropane metabolic process	biological_process	The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.
GO:0018977	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	biological_process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
GO:0018978	anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	biological_process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.
GO:0018979	trichloroethylene metabolic process	biological_process	The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
GO:0018980	2,4,5-trichlorophenoxyacetic acid metabolic process	biological_process	The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.
GO:0018982	vanillin metabolic process	biological_process	The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.
GO:0018983	Z-phenylacetaldoxime metabolic process	biological_process	The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants.
GO:0018984	naphthalenesulfonate metabolic process	biological_process	The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene.
GO:0018985	pronuclear envelope synthesis	biological_process	Synthesis and ordering of the envelope of pronuclei.
GO:0018989	apolysis	biological_process	The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.
GO:0018990	ecdysis, chitin-based cuticle	biological_process	The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.
GO:0018991	egg-laying behavior	biological_process	A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
GO:0018992	germ-line sex determination	biological_process	The determination of sex and sexual phenotype in an organism's germ line.
GO:0018993	somatic sex determination	biological_process	The determination of sex and sexual phenotypes in an organism's soma.
GO:0018995	host cellular component	cellular_component	Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.
GO:0018996	molting cycle, collagen and cuticulin-based cuticle	biological_process	The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.
GO:0019001	guanyl nucleotide binding	molecular_function	Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate.
GO:0019002	GMP binding	molecular_function	Binding to GMP, guanosine monophosphate.
GO:0019003	GDP binding	molecular_function	Binding to GDP, guanosine 5'-diphosphate.
GO:0019005	SCF ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
GO:0019008	molybdopterin synthase complex	cellular_component	A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
GO:0019010	farnesoic acid O-methyltransferase activity	molecular_function	Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine.
GO:0019013	viral nucleocapsid	cellular_component	The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.
GO:0019028	viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.
GO:0019029	helical viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.
GO:0019030	icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.
GO:0019031	viral envelope	cellular_component	The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
GO:0019033	viral tegument	cellular_component	A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.
GO:0019034	viral replication complex	cellular_component	Specific locations and structures in the virus infected cell involved in replicating the viral genome.
GO:0019035	viral integration complex	cellular_component	A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins.
GO:0019036	viral transcriptional complex	cellular_component	Specific locations and structures in the virus infected cell involved in transcribing the viral genome.
GO:0019042	viral latency	biological_process	The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.
GO:0019043	establishment of viral latency	biological_process	A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.
GO:0019044	maintenance of viral latency	biological_process	The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.
GO:0019045	latent virus replication	biological_process	Any process required for latent viral replication in a cell.
GO:0019046	release from viral latency	biological_process	The process by which a virus begins to replicate following a latency replication decision (switch).
GO:0019048	modulation by virus of host process	biological_process	The process in which a virus effects a change in the structure or processes of its host organism.
GO:0019049	mitigation of host antiviral defense response	biological_process	A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0019050	suppression by virus of host apoptotic process	biological_process	Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.
GO:0019051	induction by virus of host apoptotic process	biological_process	Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
GO:0019054	modulation by virus of host cellular process	biological_process	The process in which a virus effects a change in the processes and activities of its host organism.
GO:0019055	perturbation by virus of host cell cycle regulation	biological_process	Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.
GO:0019056	modulation by virus of host transcription	biological_process	Any process in which a virus modulates the frequency, rate or extent of its host's transcription.
GO:0019057	modulation by virus of host translation	biological_process	Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA.
GO:0019058	viral life cycle	biological_process	A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.
GO:0019060	intracellular transport of viral protein in host cell	biological_process	The directed movement of a viral protein within the host cell.
GO:0019061	uncoating of virus	biological_process	The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.
GO:0019062	virion attachment to host cell	biological_process	The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.
GO:0019064	fusion of virus membrane with host plasma membrane	biological_process	Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
GO:0019065	receptor-mediated endocytosis of virus by host cell	biological_process	Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.
GO:0019068	virion assembly	biological_process	A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.
GO:0019069	viral capsid assembly	biological_process	The assembly of a virus capsid from its protein subunits.
GO:0019070	viral genome maturation	biological_process	The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.
GO:0019071	viral DNA cleavage involved in viral genome maturation	biological_process	The cleavage of viral DNA into singular functional units.
GO:0019072	viral genome packaging	biological_process	The encapsulation of the viral genome within the capsid.
GO:0019073	viral DNA genome packaging	biological_process	The packing of viral DNA into a capsid.
GO:0019074	viral RNA genome packaging	biological_process	The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid.
GO:0019075	virus maturation	biological_process	The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.
GO:0019076	viral release from host cell	biological_process	The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.
GO:0019079	viral genome replication	biological_process	Any process involved directly in viral genome replication, including viral nucleotide metabolism.
GO:0019080	viral gene expression	biological_process	A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.
GO:0019081	viral translation	biological_process	A process by which viral mRNA is translated into viral protein, using the host cellular machinery.
GO:0019082	viral protein processing	biological_process	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.
GO:0019083	viral transcription	biological_process	The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
GO:0019084	middle viral transcription	biological_process	The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.
GO:0019085	early viral transcription	biological_process	The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.
GO:0019086	late viral transcription	biological_process	The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.
GO:0019087	transformation of host cell by virus	biological_process	A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.
GO:0019090	mitochondrial rRNA export from mitochondrion	biological_process	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.
GO:0019091	mitochondrial lrRNA export from mitochondrion	biological_process	The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.
GO:0019092	mitochondrial srRNA export from mitochondrion	biological_process	The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.
GO:0019093	mitochondrial RNA localization	biological_process	Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.
GO:0019094	pole plasm mRNA localization	biological_process	Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0019095	pole plasm mitochondrial rRNA localization	biological_process	Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0019096	pole plasm mitochondrial lrRNA localization	biological_process	Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0019097	pole plasm mitochondrial srRNA localization	biological_process	Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
GO:0019098	reproductive behavior	biological_process	The specific behavior of an organism that is associated with reproduction.
GO:0019099	female germ-line sex determination	biological_process	The determination of sex and sexual phenotype in a female organism's germ line.
GO:0019100	male germ-line sex determination	biological_process	The determination of sex and sexual phenotype in a male organism's germ line.
GO:0019101	female somatic sex determination	biological_process	The determination of sex and sexual phenotypes in a female organism's soma.
GO:0019102	male somatic sex determination	biological_process	The determination of sex and sexual phenotypes in a male organism's soma.
GO:0019103	pyrimidine nucleotide binding	molecular_function	Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.
GO:0019104	DNA N-glycosylase activity	molecular_function	Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO:0019107	myristoyltransferase activity	molecular_function	Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.
GO:0019108	aryl-aldehyde dehydrogenase (NAD) activity	molecular_function	Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.
GO:0019111	phenanthrol sulfotransferase activity	molecular_function	Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.
GO:0019112	phenanthrol glycosyltransferase activity	molecular_function	Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O.
GO:0019113	limonene monooxygenase activity	molecular_function	Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.
GO:0019114	catechol dioxygenase activity	molecular_function	Catalysis of the reaction: catechol + O2 = a muconate.
GO:0019115	benzaldehyde dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
GO:0019116	hydroxy-nicotine oxidase activity	molecular_function	Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.
GO:0019117	dihydroxyfluorene dioxygenase activity	molecular_function	Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.
GO:0019118	phenanthrene-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.
GO:0019119	phenanthrene-9,10-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene.
GO:0019120	hydrolase activity, acting on acid halide bonds, in C-halide compounds	molecular_function	Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.
GO:0019121	peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine	biological_process	The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.
GO:0019122	peptidyl-D-alanine racemization	biological_process	The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.
GO:0019123	peptidyl-methionine racemization	biological_process	The racemization of peptidyl-methionine.
GO:0019124	peptidyl-isoleucine racemization	biological_process	The racemization of peptidyl-isoleucine.
GO:0019125	peptidyl-phenylalanine racemization	biological_process	The racemization of peptidyl-phenylalanine.
GO:0019126	peptidyl-serine racemization	biological_process	The racemization of peptidyl-serine.
GO:0019128	peptidyl-tryptophan racemization	biological_process	The racemization of peptidyl-tryptophan.
GO:0019129	peptidyl-leucine racemization	biological_process	The racemization of peptidyl-leucine.
GO:0019133	choline monooxygenase activity	molecular_function	Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.
GO:0019134	glucosamine-1-phosphate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H+.
GO:0019135	deoxyhypusine monooxygenase activity	molecular_function	Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
GO:0019136	deoxynucleoside kinase activity	molecular_function	Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
GO:0019137	thioglucosidase activity	molecular_function	Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.
GO:0019139	cytokinin dehydrogenase activity	molecular_function	Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.
GO:0019140	inositol 3-kinase activity	molecular_function	Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.
GO:0019141	2-dehydropantolactone reductase (B-specific) activity	molecular_function	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
GO:0019142	2-hydroxyglutarate synthase activity	molecular_function	Catalysis of the reaction: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H+.
GO:0019143	3-deoxy-manno-octulosonate-8-phosphatase activity	molecular_function	Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H2O = 3-deoxy-D-manno-octulosonate + phosphate.
GO:0019144	ADP-sugar diphosphatase activity	molecular_function	Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.
GO:0019145	aminobutyraldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.
GO:0019146	arabinose-5-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H+.
GO:0019147	(R)-aminopropanol dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + H+ + NADH.
GO:0019148	D-cysteine desulfhydrase activity	molecular_function	Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.
GO:0019149	3-chloro-D-alanine dehydrochlorinase activity	molecular_function	Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.
GO:0019150	D-ribulokinase activity	molecular_function	Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate.
GO:0019151	galactose 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.
GO:0019152	acetoin dehydrogenase activity	molecular_function	Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+.
GO:0019153	protein-disulfide reductase (glutathione) activity	molecular_function	Catalysis of the reaction: 2 glutathione + protein-disulfide = glutathione disulfide+ protein-dithiol.
GO:0019154	glycolate dehydrogenase activity	molecular_function	Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate.
GO:0019155	3-(imidazol-5-yl)lactate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.
GO:0019156	isoamylase activity	molecular_function	Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.
GO:0019158	mannokinase activity	molecular_function	Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate.
GO:0019159	nicotinamide-nucleotide amidase activity	molecular_function	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.
GO:0019160	NMN nucleosidase activity	molecular_function	Catalysis of the reaction: H2O + nicotinamide mononucleotide = D-ribose 5-phosphate + H+ + nicotinamide.
GO:0019161	diamine transaminase activity	molecular_function	Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.
GO:0019162	pyridoxamine-oxaloacetate transaminase activity	molecular_function	Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.
GO:0019163	pyridoxamine-phosphate transaminase activity	molecular_function	Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.
GO:0019164	pyruvate synthase activity	molecular_function	Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
GO:0019165	thiamine kinase activity	molecular_function	Catalysis of the reaction: ATP + thiamine = ADP + 2 H+ + thiamine phosphate.
GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity	molecular_function	Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.
GO:0019168	2-octaprenylphenol hydroxylase activity	molecular_function	Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.
GO:0019170	methylglyoxal reductase (NADH-dependent) activity	molecular_function	Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.
GO:0019171	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	molecular_function	Catalysis of the reaction: a (3R)-hydroxyacyl-[acyl-carrier-protein] = a (2E)-enoyl-[acyl-carrier-protein] + H2O.
GO:0019172	glyoxalase III activity	molecular_function	Catalysis of the reaction: methylglyoxal + H2O = D-lactate.
GO:0019174	tetrahydrothiophene 1-oxide reductase activity	molecular_function	Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.
GO:0019176	dihydroneopterin monophosphate phosphatase activity	molecular_function	Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.
GO:0019177	dihydroneopterin triphosphate pyrophosphohydrolase activity	molecular_function	Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.
GO:0019178	NADP phosphatase activity	molecular_function	Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.
GO:0019179	dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity	molecular_function	Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.
GO:0019180	dTDP-4-amino-4,6-dideoxygalactose transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.
GO:0019181	halohydrin hydrogen-halide-lyase activity	molecular_function	Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.
GO:0019182	histamine-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts.
GO:0019183	histamine-gated chloride channel complex	cellular_component	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.
GO:0019184	nonribosomal peptide biosynthetic process	biological_process	The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
GO:0019185	snRNA-activating protein complex	cellular_component	A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
GO:0019186	acyl-CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.
GO:0019187	beta-1,4-mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.
GO:0019191	cellobiose transmembrane transporter activity	molecular_function	Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
GO:0019194	sorbose transmembrane transporter activity	molecular_function	Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
GO:0019196	galactosamine transmembrane transporter activity	molecular_function	Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.
GO:0019197	phosphoenolpyruvate-dependent sugar phosphotransferase complex	cellular_component	Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).
GO:0019198	transmembrane receptor protein phosphatase activity	molecular_function	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.
GO:0019199	transmembrane receptor protein kinase activity	molecular_function	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0019200	carbohydrate kinase activity	molecular_function	Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.
GO:0019202	amino acid kinase activity	molecular_function	Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.
GO:0019203	carbohydrate phosphatase activity	molecular_function	Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.
GO:0019205	nucleobase-containing compound kinase activity	molecular_function	Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.
GO:0019206	nucleoside kinase activity	molecular_function	Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.
GO:0019207	kinase regulator activity	molecular_function	Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0019208	phosphatase regulator activity	molecular_function	Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
GO:0019209	kinase activator activity	molecular_function	Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0019210	kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a kinase.
GO:0019211	phosphatase activator activity	molecular_function	Binds to and increases the activity of a phosphatase.
GO:0019212	phosphatase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a phosphatase.
GO:0019213	deacetylase activity	molecular_function	Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
GO:0019215	intermediate filament binding	molecular_function	Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.
GO:0019216	regulation of lipid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GO:0019217	regulation of fatty acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
GO:0019218	regulation of steroid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
GO:0019219	regulation of nucleobase-containing compound metabolic process	biological_process	Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0019220	regulation of phosphate metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GO:0019221	cytokine-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0019222	regulation of metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0019226	transmission of nerve impulse	biological_process	The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
GO:0019227	neuronal action potential propagation	biological_process	The propagation of an action potential along an axon, away from the soma.
GO:0019228	neuronal action potential	biological_process	An action potential that occurs in a neuron.
GO:0019229	regulation of vasoconstriction	biological_process	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.
GO:0019230	proprioception	biological_process	The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.
GO:0019231	perception of static position	biological_process	The perception of the orientation of different parts of the body with respect to one another.
GO:0019232	perception of rate of movement	biological_process	The series of events by which an organism senses the speed and direction of movement of the body and its parts.
GO:0019233	sensory perception of pain	biological_process	The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
GO:0019234	sensory perception of fast pain	biological_process	The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.
GO:0019235	sensory perception of slow pain	biological_process	The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.
GO:0019236	response to pheromone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
GO:0019237	centromeric DNA binding	molecular_function	Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.
GO:0019238	cyclohydrolase activity	molecular_function	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.
GO:0019239	deaminase activity	molecular_function	Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R).
GO:0019240	citrulline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
GO:0019241	citrulline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
GO:0019242	methylglyoxal biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	biological_process	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
GO:0019244	lactate biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate.
GO:0019245	D(-)-lactate biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate.
GO:0019246	L(+)-lactate biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.
GO:0019247	lactate racemization	biological_process	Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.
GO:0019248	D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde	biological_process	The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde.
GO:0019249	lactate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.
GO:0019250	aerobic cobalamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.
GO:0019251	anaerobic cobalamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.
GO:0019252	starch biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.
GO:0019253	reductive pentose-phosphate cycle	biological_process	The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.
GO:0019254	carnitine metabolic process, CoA-linked	biological_process	The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.
GO:0019255	glucose 1-phosphate metabolic process	biological_process	The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.
GO:0019256	acrylonitrile catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.
GO:0019257	4-nitrotoluene metabolic process	biological_process	The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor.
GO:0019258	4-nitrotoluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.
GO:0019260	1,2-dichloroethane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
GO:0019261	1,4-dichlorobenzene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.
GO:0019262	N-acetylneuraminate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
GO:0019263	adamantanone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.
GO:0019264	glycine biosynthetic process from serine	biological_process	The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	biological_process	The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.
GO:0019266	asparagine biosynthetic process from oxaloacetate	biological_process	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate.
GO:0019267	asparagine biosynthetic process from cysteine	biological_process	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.
GO:0019270	aerobactin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
GO:0019271	aerobactin transport	biological_process	The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
GO:0019272	L-alanine biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.
GO:0019273	L-alanine biosynthetic process via ornithine	biological_process	The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.
GO:0019276	UDP-N-acetylgalactosamine metabolic process	biological_process	The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0019277	UDP-N-acetylgalactosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0019278	UDP-N-acetylgalactosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
GO:0019279	L-methionine biosynthetic process from L-homoserine via cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.
GO:0019280	L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.
GO:0019281	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.
GO:0019283	L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.
GO:0019284	L-methionine salvage from S-adenosylmethionine	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.
GO:0019285	glycine betaine biosynthetic process from choline	biological_process	The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.
GO:0019286	glycine betaine biosynthetic process from glycine	biological_process	The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine.
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	biological_process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	biological_process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
GO:0019289	rhizobactin 1021 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.
GO:0019290	siderophore biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
GO:0019292	tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate	biological_process	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate.
GO:0019293	tyrosine biosynthetic process, by oxidation of phenylalanine	biological_process	The conversion of phenylalanine to tyrosine.
GO:0019294	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.
GO:0019295	coenzyme M biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
GO:0019296	coenzyme M metabolic process	biological_process	The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
GO:0019297	coenzyme B metabolic process	biological_process	The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
GO:0019298	coenzyme B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
GO:0019299	rhamnose metabolic process	biological_process	The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
GO:0019300	rhamnose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.
GO:0019301	rhamnose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
GO:0019302	D-ribose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).
GO:0019303	D-ribose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
GO:0019304	anaerobic rhamnose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen.
GO:0019305	dTDP-rhamnose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
GO:0019306	GDP-D-rhamnose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
GO:0019307	mannose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
GO:0019308	dTDP-mannose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.
GO:0019309	mannose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
GO:0019310	inositol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
GO:0019311	sorbose metabolic process	biological_process	The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
GO:0019312	L-sorbose metabolic process	biological_process	The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
GO:0019313	allose metabolic process	biological_process	The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
GO:0019314	D-allose metabolic process	biological_process	The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
GO:0019315	D-allose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
GO:0019316	D-allose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
GO:0019317	fucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose).
GO:0019318	hexose metabolic process	biological_process	The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
GO:0019319	hexose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
GO:0019320	hexose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
GO:0019321	pentose metabolic process	biological_process	The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
GO:0019322	pentose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
GO:0019323	pentose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
GO:0019324	L-lyxose metabolic process	biological_process	The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.
GO:0019325	anaerobic fructose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.
GO:0019326	nitrotoluene metabolic process	biological_process	The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.
GO:0019327	lead sulfide oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate.
GO:0019328	anaerobic gallate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.
GO:0019329	ammonia oxidation	biological_process	The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.
GO:0019330	aldoxime metabolic process	biological_process	The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.
GO:0019331	anaerobic respiration, using ammonium as electron donor	biological_process	The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.
GO:0019332	aerobic respiration, using nitrite as electron donor	biological_process	The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.
GO:0019333	denitrification pathway	biological_process	The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.
GO:0019334	p-cymene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.
GO:0019335	3-methylquinoline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.
GO:0019336	phenol-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
GO:0019337	tetrachloroethylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.
GO:0019338	pentachlorophenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.
GO:0019339	parathion catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.
GO:0019340	dibenzofuran catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.
GO:0019341	dibenzo-p-dioxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.
GO:0019342	trypanothione biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.
GO:0019343	cysteine biosynthetic process via cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.
GO:0019344	cysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
GO:0019345	cysteine biosynthetic process via S-sulfo-L-cysteine	biological_process	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.
GO:0019346	transsulfuration	biological_process	The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
GO:0019347	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.
GO:0019348	dolichol metabolic process	biological_process	The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
GO:0019349	ribitol metabolic process	biological_process	The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.
GO:0019350	teichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
GO:0019351	dethiobiotin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms.
GO:0019352	protoporphyrinogen IX biosynthetic process from glycine	biological_process	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.
GO:0019353	protoporphyrinogen IX biosynthetic process from glutamate	biological_process	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.
GO:0019354	siroheme biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
GO:0019356	nicotinate nucleotide biosynthetic process from tryptophan	biological_process	The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.
GO:0019357	nicotinate nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).
GO:0019358	nicotinate nucleotide salvage	biological_process	The generation of nicotinate nucleotide without de novo synthesis.
GO:0019359	nicotinamide nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
GO:0019360	nicotinamide nucleotide biosynthetic process from niacinamide	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.
GO:0019361	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
GO:0019362	pyridine nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
GO:0019363	pyridine nucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
GO:0019364	pyridine nucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
GO:0019365	pyridine nucleotide salvage	biological_process	Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.
GO:0019367	fatty acid elongation, saturated fatty acid	biological_process	Elongation of a saturated fatty acid chain.
GO:0019368	fatty acid elongation, unsaturated fatty acid	biological_process	Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.
GO:0019369	arachidonic acid metabolic process	biological_process	The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
GO:0019370	leukotriene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
GO:0019371	cyclooxygenase pathway	biological_process	The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
GO:0019372	lipoxygenase pathway	biological_process	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
GO:0019373	epoxygenase P450 pathway	biological_process	The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
GO:0019374	galactolipid metabolic process	biological_process	The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
GO:0019375	galactolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
GO:0019376	galactolipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
GO:0019377	glycolipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
GO:0019379	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)	biological_process	The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).
GO:0019380	3-phenylpropionate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.
GO:0019381	atrazine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.
GO:0019382	carbon tetrachloride catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
GO:0019383	(+)-camphor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.
GO:0019384	caprolactam catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.
GO:0019385	methanogenesis, from acetate	biological_process	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.
GO:0019386	methanogenesis, from carbon dioxide	biological_process	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).
GO:0019387	methanogenesis, from methanol	biological_process	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.
GO:0019388	galactose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.
GO:0019389	glucuronoside metabolic process	biological_process	The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.
GO:0019390	glucuronoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.
GO:0019391	glucuronoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.
GO:0019392	glucarate metabolic process	biological_process	The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.
GO:0019393	glucarate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.
GO:0019394	glucarate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.
GO:0019395	fatty acid oxidation	biological_process	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
GO:0019396	gallate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).
GO:0019397	gallate catabolic process via 2-pyrone-4,6-dicarboxylate	biological_process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.
GO:0019398	gallate catabolic process via gallate dioxygenase activity	biological_process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.
GO:0019399	cyclohexanol oxidation	biological_process	The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.
GO:0019400	alditol metabolic process	biological_process	The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
GO:0019401	alditol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
GO:0019402	galactitol metabolic process	biological_process	The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
GO:0019403	galactitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
GO:0019404	galactitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
GO:0019405	alditol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
GO:0019406	hexitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.
GO:0019407	hexitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.
GO:0019408	dolichol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
GO:0019409	aerobic respiration, using ammonia as electron donor	biological_process	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.
GO:0019410	aerobic respiration, using carbon monoxide as electron donor	biological_process	The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.
GO:0019411	aerobic respiration, using ferrous ions as electron donor	biological_process	The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.
GO:0019412	aerobic respiration, using hydrogen as electron donor	biological_process	The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.
GO:0019413	acetate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.
GO:0019414	aerobic respiration, using sulfur or sulfate as electron donor	biological_process	An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.
GO:0019415	acetate biosynthetic process from carbon monoxide	biological_process	The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide.
GO:0019416	polythionate oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.
GO:0019417	sulfur oxidation	biological_process	The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.
GO:0019418	sulfide oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.
GO:0019419	sulfate reduction	biological_process	The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.
GO:0019420	dissimilatory sulfate reduction	biological_process	The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.
GO:0019422	disproportionation of elemental sulfur	biological_process	The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.
GO:0019423	sulfur oxidation, ferric ion-dependent	biological_process	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).
GO:0019424	sulfide oxidation, using siroheme sulfite reductase	biological_process	A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase.
GO:0019426	bisulfite reduction	biological_process	The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite.
GO:0019427	acetyl-CoA biosynthetic process from acetate	biological_process	The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.
GO:0019428	allantoin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
GO:0019429	fluorene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
GO:0019430	removal of superoxide radicals	biological_process	Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
GO:0019431	acetyl-CoA biosynthetic process from ethanol	biological_process	The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde.
GO:0019432	triglyceride biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
GO:0019433	triglyceride catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
GO:0019434	sophorosyloxydocosanoate metabolic process	biological_process	The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.
GO:0019435	sophorosyloxydocosanoate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.
GO:0019436	sophorosyloxydocosanoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.
GO:0019438	aromatic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
GO:0019439	aromatic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
GO:0019440	tryptophan catabolic process to indole-3-acetate	biological_process	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate.
GO:0019441	tryptophan catabolic process to kynurenine	biological_process	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
GO:0019442	tryptophan catabolic process to acetyl-CoA	biological_process	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.
GO:0019444	tryptophan catabolic process to catechol	biological_process	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.
GO:0019445	tyrosine catabolic process to fumarate	biological_process	The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate.
GO:0019447	D-cysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.
GO:0019448	L-cysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.
GO:0019449	L-cysteine catabolic process to hypotaurine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.
GO:0019450	L-cysteine catabolic process to pyruvate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.
GO:0019451	L-cysteine catabolic process to pyruvate, using cysteine dioxygenase	biological_process	The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).
GO:0019452	L-cysteine catabolic process to taurine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.
GO:0019453	L-cysteine catabolic process via cystine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.
GO:0019454	L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase	biological_process	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase.
GO:0019455	L-cysteine catabolic process via cystine, using cystine reductase	biological_process	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase.
GO:0019456	L-cysteine catabolic process via cystine, using cysteine transaminase	biological_process	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase.
GO:0019457	methionine catabolic process to succinyl-CoA	biological_process	The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA.
GO:0019458	methionine catabolic process via 2-oxobutanoate	biological_process	The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate.
GO:0019460	glutamine catabolic process to fumarate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.
GO:0019461	glutamine catabolic process to fumarate, using glutamate synthase (NADPH)	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).
GO:0019462	glutamine catabolic process to fumarate, using glutaminase	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2).
GO:0019463	glycine catabolic process to creatine	biological_process	The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.
GO:0019464	glycine decarboxylation via glycine cleavage system	biological_process	The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
GO:0019465	aspartate transamidation	biological_process	The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.
GO:0019466	ornithine catabolic process via proline	biological_process	The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.
GO:0019467	ornithine catabolic process, by decarboxylation	biological_process	The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation.
GO:0019468	nopaline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.
GO:0019469	octopine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.
GO:0019470	4-hydroxyproline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
GO:0019471	4-hydroxyproline metabolic process	biological_process	The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.
GO:0019472	4-hydroxyproline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
GO:0019473	L-lysine catabolic process to glutarate, by acetylation	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.
GO:0019474	L-lysine catabolic process to acetyl-CoA	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA.
GO:0019475	L-lysine catabolic process to acetate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.
GO:0019476	D-lysine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.
GO:0019477	L-lysine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
GO:0019478	D-amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.
GO:0019479	L-alanine oxidation to D-lactate and ammonia	biological_process	The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.
GO:0019480	L-alanine oxidation to pyruvate via D-alanine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.
GO:0019481	L-alanine catabolic process, by transamination	biological_process	The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination.
GO:0019482	beta-alanine metabolic process	biological_process	The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
GO:0019483	beta-alanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
GO:0019484	beta-alanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
GO:0019485	beta-alanine catabolic process to L-alanine	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.
GO:0019486	beta-alanine catabolic process to mevalonate semialdehyde, by transamination	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.
GO:0019487	anaerobic acetylene catabolic process	biological_process	The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.
GO:0019488	ribitol catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate.
GO:0019489	methylgallate metabolic process	biological_process	The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
GO:0019490	2-aminobenzenesulfonate desulfonation	biological_process	The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
GO:0019491	ectoine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
GO:0019492	proline salvage	biological_process	Any process which produces the amino acid proline from derivatives of it, without de novo synthesis.
GO:0019493	arginine catabolic process to proline	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline.
GO:0019495	proline catabolic process to 2-oxoglutarate	biological_process	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.
GO:0019496	serine-isocitrate lyase pathway	biological_process	A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.
GO:0019497	hexachlorocyclohexane metabolic process	biological_process	The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.
GO:0019498	n-octane oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA.
GO:0019499	cyanide metabolic process	biological_process	The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.
GO:0019500	cyanide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.
GO:0019501	arsonoacetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.
GO:0019502	L-proline betaine metabolic process	biological_process	The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.
GO:0019503	L-proline betaine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.
GO:0019504	L-proline betaine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.
GO:0019505	resorcinol metabolic process	biological_process	The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.
GO:0019506	phenylmercury acetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.
GO:0019507	pyridine metabolic process	biological_process	The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
GO:0019508	2,5-dihydroxypyridine catabolic process to fumarate	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.
GO:0019509	L-methionine salvage from methylthioadenosine	biological_process	The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
GO:0019510	S-adenosylhomocysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.
GO:0019511	peptidyl-proline hydroxylation	biological_process	The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.
GO:0019512	lactose catabolic process via tagatose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.
GO:0019513	lactose catabolic process, using glucoside 3-dehydrogenase	biological_process	The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase.
GO:0019515	lactose catabolic process via UDP-galactose	biological_process	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.
GO:0019516	lactate oxidation	biological_process	The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.
GO:0019517	L-threonine catabolic process to D-lactate	biological_process	The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.
GO:0019518	L-threonine catabolic process to glycine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.
GO:0019519	pentitol metabolic process	biological_process	The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.
GO:0019520	aldonic acid metabolic process	biological_process	The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
GO:0019521	D-gluconate metabolic process	biological_process	The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
GO:0019522	ketogluconate metabolic process	biological_process	The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
GO:0019523	L-idonate metabolic process	biological_process	The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
GO:0019524	keto-D-gluconate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
GO:0019525	keto-D-gluconate metabolic process	biological_process	The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
GO:0019526	pentitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.
GO:0019527	pentitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.
GO:0019528	D-arabitol catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.
GO:0019529	taurine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
GO:0019530	taurine metabolic process	biological_process	The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
GO:0019531	oxalate transmembrane transporter activity	molecular_function	Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
GO:0019532	oxalate transport	biological_process	The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
GO:0019533	cellobiose transport	biological_process	The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
GO:0019534	toxin transmembrane transporter activity	molecular_function	Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0019535	ferric-vibriobactin transmembrane transporter activity	molecular_function	Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other.
GO:0019536	vibriobactin metabolic process	biological_process	The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.
GO:0019537	vibriobactin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.
GO:0019538	protein metabolic process	biological_process	The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0019539	hydroxymate-containing siderophore biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).
GO:0019540	catechol-containing siderophore biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+).
GO:0019541	propionate metabolic process	biological_process	The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.
GO:0019542	propionate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.
GO:0019543	propionate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.
GO:0019544	arginine catabolic process to glutamate	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
GO:0019545	arginine catabolic process to succinate	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.
GO:0019546	arginine deiminase pathway	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
GO:0019547	arginine catabolic process to ornithine	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.
GO:0019548	arginine catabolic process to spermine	biological_process	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.
GO:0019549	glutamate catabolic process to succinate via succinate semialdehyde	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase.
GO:0019550	glutamate catabolic process to aspartate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.
GO:0019551	glutamate catabolic process to 2-oxoglutarate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.
GO:0019552	glutamate catabolic process via 2-hydroxyglutarate	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP.
GO:0019553	glutamate catabolic process via L-citramalate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.
GO:0019554	glutamate catabolic process to oxaloacetate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.
GO:0019555	glutamate catabolic process to ornithine	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.
GO:0019556	histidine catabolic process to glutamate and formamide	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide.
GO:0019557	histidine catabolic process to glutamate and formate	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate.
GO:0019558	histidine catabolic process to 2-oxoglutarate	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate.
GO:0019559	histidine catabolic process to imidazol-5-yl-lactate	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate.
GO:0019560	histidine catabolic process to hydantoin-5-propionate	biological_process	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.
GO:0019561	anaerobic phenylalanine oxidation	biological_process	The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.
GO:0019563	glycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
GO:0019564	aerobic glycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.
GO:0019566	arabinose metabolic process	biological_process	The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.
GO:0019567	arabinose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.
GO:0019568	arabinose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.
GO:0019569	L-arabinose catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.
GO:0019570	L-arabinose catabolic process to 2-oxoglutarate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.
GO:0019571	D-arabinose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.
GO:0019572	L-arabinose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.
GO:0019573	D-arabinose catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate.
GO:0019574	sucrose catabolic process via 3'-ketosucrose	biological_process	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.
GO:0019576	aerobic fructose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen.
GO:0019577	aldaric acid metabolic process	biological_process	The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
GO:0019578	aldaric acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
GO:0019579	aldaric acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
GO:0019580	galactarate metabolic process	biological_process	The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.
GO:0019583	galactonate metabolic process	biological_process	The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.
GO:0019584	galactonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid.
GO:0019585	glucuronate metabolic process	biological_process	The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
GO:0019586	galacturonate metabolic process	biological_process	The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
GO:0019588	anaerobic glycerol catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.
GO:0019589	anaerobic glycerol catabolic process to propane-1,3-diol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.
GO:0019590	L-arabitol catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.
GO:0019592	mannitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
GO:0019593	mannitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
GO:0019594	mannitol metabolic process	biological_process	The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
GO:0019595	non-phosphorylated glucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.
GO:0019596	mandelate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
GO:0019597	(R)-mandelate catabolic process to benzoate	biological_process	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate.
GO:0019598	(R)-mandelate catabolic process to catechol	biological_process	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol.
GO:0019599	(R)-4-hydroxymandelate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.
GO:0019600	toluene oxidation	biological_process	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.
GO:0019601	toluene oxidation via 2-hydroxytoluene	biological_process	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).
GO:0019602	toluene oxidation via 3-hydroxytoluene	biological_process	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).
GO:0019603	toluene oxidation via 4-hydroxytoluene	biological_process	The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).
GO:0019604	toluene oxidation to catechol	biological_process	The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).
GO:0019605	butyrate metabolic process	biological_process	The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.
GO:0019606	2-oxobutyrate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
GO:0019607	phenylethylamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
GO:0019608	nicotine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
GO:0019609	3-hydroxyphenylacetate metabolic process	biological_process	The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
GO:0019610	3-hydroxyphenylacetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
GO:0019611	4-toluenecarboxylate metabolic process	biological_process	The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.
GO:0019612	4-toluenecarboxylate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.
GO:0019614	catechol-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.
GO:0019615	catechol catabolic process, ortho-cleavage	biological_process	The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.
GO:0019616	catechol catabolic process, meta-cleavage	biological_process	The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.
GO:0019617	protocatechuate catabolic process, meta-cleavage	biological_process	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.
GO:0019618	protocatechuate catabolic process, ortho-cleavage	biological_process	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.
GO:0019619	3,4-dihydroxybenzoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.
GO:0019620	aerobic benzoate metabolic process	biological_process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.
GO:0019621	creatinine catabolic process to formate	biological_process	The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.
GO:0019622	3-(3-hydroxy)phenylpropionate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.
GO:0019623	atrazine catabolic process to urea	biological_process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea.
GO:0019624	atrazine catabolic process to isopropylamine	biological_process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.
GO:0019625	atrazine catabolic process to cyanuric acid	biological_process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.
GO:0019626	short-chain fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0019627	urea metabolic process	biological_process	The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.
GO:0019628	urate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.
GO:0019629	propionate catabolic process, 2-methylcitrate cycle	biological_process	The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
GO:0019630	quinate metabolic process	biological_process	The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.
GO:0019631	quinate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.
GO:0019632	shikimate metabolic process	biological_process	The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.
GO:0019633	shikimate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.
GO:0019634	organic phosphonate metabolic process	biological_process	The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
GO:0019635	2-aminoethylphosphonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.
GO:0019636	phosphonoacetate metabolic process	biological_process	The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.
GO:0019637	organophosphate metabolic process	biological_process	The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
GO:0019638	6-hydroxycineole metabolic process	biological_process	The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.
GO:0019639	6-hydroxycineole catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.
GO:0019640	glucuronate catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.
GO:0019643	reductive tricarboxylic acid cycle	biological_process	A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.
GO:0019645	anaerobic electron transport chain	biological_process	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.
GO:0019646	aerobic electron transport chain	biological_process	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.
GO:0019647	formaldehyde assimilation via ribulose monophosphate cycle	biological_process	The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.
GO:0019648	formaldehyde assimilation via xylulose monophosphate cycle	biological_process	The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.
GO:0019649	formaldehyde assimilation	biological_process	The pathways in which formaldehyde is processed and used as a carbon source for the cell.
GO:0019650	glycolytic fermentation to butanediol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.
GO:0019651	citrate catabolic process to diacetyl	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.
GO:0019652	lactate fermentation to propionate and acetate	biological_process	The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).
GO:0019653	anaerobic purine nucleobase catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.
GO:0019654	acetate fermentation	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.
GO:0019655	glycolytic fermentation to ethanol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.
GO:0019656	glucose catabolic process to D-lactate and ethanol	biological_process	The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.
GO:0019657	glycolytic fermentation to propionate	biological_process	Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.
GO:0019658	glucose fermentation to lactate and acetate	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.
GO:0019659	glucose catabolic process to lactate	biological_process	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP).
GO:0019660	glycolytic fermentation	biological_process	Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
GO:0019661	glucose catabolic process to lactate via pyruvate	biological_process	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).
GO:0019662	non-glycolytic fermentation	biological_process	Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
GO:0019664	mixed acid fermentation	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP.
GO:0019665	anaerobic amino acid catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.
GO:0019666	nitrogenous compound fermentation	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.
GO:0019667	anaerobic L-alanine catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.
GO:0019668	anaerobic catabolism of pairs of amino acids	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.
GO:0019669	anaerobic glycine catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.
GO:0019670	anaerobic glutamate catabolic process	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP.
GO:0019671	glutamate catabolic process via mesaconate and citramalate	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP.
GO:0019672	ethanol-acetate fermentation to butyrate and caproate	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.
GO:0019673	GDP-mannose metabolic process	biological_process	The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
GO:0019674	NAD metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
GO:0019676	ammonia assimilation cycle	biological_process	The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
GO:0019677	NAD catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0019678	propionate metabolic process, methylmalonyl pathway	biological_process	The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway.
GO:0019679	propionate metabolic process, methylcitrate cycle	biological_process	The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
GO:0019680	L-methylmalonyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.
GO:0019681	acetyl-CoA assimilation pathway	biological_process	The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.
GO:0019682	glyceraldehyde-3-phosphate metabolic process	biological_process	The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
GO:0019683	glyceraldehyde-3-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
GO:0019684	photosynthesis, light reaction	biological_process	The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.
GO:0019685	photosynthesis, dark reaction	biological_process	A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.
GO:0019686	purine nucleoside interconversion	biological_process	The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.
GO:0019687	pyruvate biosynthetic process from acetate	biological_process	The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.
GO:0019688	purine deoxyribonucleoside interconversion	biological_process	The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.
GO:0019689	pyrimidine nucleoside interconversion	biological_process	The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.
GO:0019690	pyrimidine deoxyribonucleoside interconversion	biological_process	The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.
GO:0019692	deoxyribose phosphate metabolic process	biological_process	The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
GO:0019693	ribose phosphate metabolic process	biological_process	The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.
GO:0019694	alkanesulfonate metabolic process	biological_process	The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
GO:0019695	choline metabolic process	biological_process	The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
GO:0019696	toluene oxidation via toluene-cis-1,2-dihydrodiol	biological_process	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.
GO:0019697	L-xylitol catabolic process to xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.
GO:0019698	D-galacturonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
GO:0019700	organic phosphonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
GO:0019701	peptidyl-arginine N5-methylation	biological_process	The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.
GO:0019702	protein arginine N5-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.
GO:0019703	coenzyme A-peptidyl-cysteine covalent linking	biological_process	The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide.
GO:0019704	peptidyl-L-cysteine S-myristoylation	biological_process	The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine.
GO:0019705	protein-cysteine S-myristoyltransferase activity	molecular_function	Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].
GO:0019706	protein-cysteine S-palmitoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].
GO:0019707	protein-cysteine S-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.
GO:0019708	peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine	biological_process	The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.
GO:0019709	iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	biological_process	The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
GO:0019711	peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid	biological_process	The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.
GO:0019715	peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid	biological_process	The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).
GO:0019716	N-terminal peptidyl-alanine monomethylation	biological_process	The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.
GO:0019720	Mo-molybdopterin cofactor metabolic process	biological_process	The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
GO:0019722	calcium-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
GO:0019724	B cell mediated immunity	biological_process	Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
GO:0019725	cellular homeostasis	biological_process	Any process involved in the maintenance of an internal steady state at the level of the cell.
GO:0019726	mevaldate reductase (NADPH) activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + NADP+ = H+ + mevaldate + NADPH.
GO:0019727	mevaldate reductase (NAD+) activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + NAD+ = H+ + mevaldate + NADH.
GO:0019728	peptidyl-allysine oxidation to 2-aminoadipic acid	biological_process	The oxidation of allysine to 2-aminoadipic acid.
GO:0019730	antimicrobial humoral response	biological_process	An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
GO:0019731	antibacterial humoral response	biological_process	An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
GO:0019732	antifungal humoral response	biological_process	An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.
GO:0019736	peptidyl-sarcosine incorporation	biological_process	The incorporation of sarcosine (N-methylglycine) into non-coded peptides.
GO:0019740	nitrogen utilization	biological_process	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
GO:0019741	pentacyclic triterpenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
GO:0019742	pentacyclic triterpenoid metabolic process	biological_process	The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
GO:0019743	hopanoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
GO:0019744	hopanoid metabolic process	biological_process	The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
GO:0019745	pentacyclic triterpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
GO:0019746	hopanoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
GO:0019747	regulation of isoprenoid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.
GO:0019748	secondary metabolic process	biological_process	The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
GO:0019749	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte	biological_process	The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.
GO:0019750	chloroplast localization	biological_process	Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.
GO:0019751	polyol metabolic process	biological_process	The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
GO:0019752	carboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0019755	one-carbon compound transport	biological_process	The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0019756	cyanogenic glycoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
GO:0019757	glycosinolate metabolic process	biological_process	The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
GO:0019758	glycosinolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
GO:0019759	glycosinolate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
GO:0019760	glucosinolate metabolic process	biological_process	The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
GO:0019761	glucosinolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0019762	glucosinolate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0019763	immunoglobulin receptor activity	molecular_function	Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019766	IgA receptor activity	molecular_function	Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019767	IgE receptor activity	molecular_function	Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019768	high-affinity IgE receptor activity	molecular_function	Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019769	low-affinity IgE receptor activity	molecular_function	Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019770	IgG receptor activity	molecular_function	Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019771	high-affinity IgG receptor activity	molecular_function	Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019772	low-affinity IgG receptor activity	molecular_function	Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0019773	proteasome core complex, alpha-subunit complex	cellular_component	The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.
GO:0019774	proteasome core complex, beta-subunit complex	cellular_component	The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.
GO:0019775	FAT10 transferase activity	molecular_function	Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.
GO:0019776	Atg8-family ligase activity	molecular_function	Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 family modifer to phosphatidylethanolamine or phosphatidylserine on a membrane.
GO:0019777	Atg12 transferase activity	molecular_function	Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.
GO:0019778	Atg12 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0019779	Atg8 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0019780	FAT10 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0019781	NEDD8 activating enzyme activity	molecular_function	Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.
GO:0019782	ISG15 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0019783	ubiquitin-like protein peptidase activity	molecular_function	An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.
GO:0019784	deNEDDylase activity	molecular_function	An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
GO:0019785	ISG15-specific peptidase activity	molecular_function	A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.
GO:0019786	protein-phosphatidylethanolamide deconjugating activity	molecular_function	Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.
GO:0019787	ubiquitin-like protein transferase activity	molecular_function	Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
GO:0019788	NEDD8 transferase activity	molecular_function	Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.
GO:0019789	SUMO transferase activity	molecular_function	Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
GO:0019797	procollagen-proline 3-dioxygenase activity	molecular_function	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.
GO:0019798	procollagen-proline dioxygenase activity	molecular_function	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.
GO:0019799	tubulin N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	biological_process	The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.
GO:0019801	cyclization of asparagine involved in intein-mediated protein splicing	biological_process	The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.
GO:0019802	cyclization of glutamine involved in intein-mediated protein splicing	biological_process	The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.
GO:0019803	peptidyl-aspartic acid carboxylation	biological_process	The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid.
GO:0019805	quinolinate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
GO:0019806	bromide peroxidase activity	molecular_function	Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.
GO:0019807	aspartoacylase activity	molecular_function	Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.
GO:0019808	polyamine binding	molecular_function	Binding to a polyamine, an organic compound containing two or more amino groups.
GO:0019809	spermidine binding	molecular_function	Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0019810	putrescine binding	molecular_function	Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
GO:0019811	cocaine binding	molecular_function	Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.
GO:0019812	type I site-specific deoxyribonuclease complex	cellular_component	A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
GO:0019813	type III site-specific deoxyribonuclease complex	cellular_component	A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
GO:0019814	immunoglobulin complex	cellular_component	A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0019815	B cell receptor complex	cellular_component	An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0019817	vesicle fusion with peroxisome	biological_process	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.
GO:0019819	P1 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.
GO:0019820	P2 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.
GO:0019821	P3 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.
GO:0019822	P4 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.
GO:0019823	P5 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.
GO:0019824	P6 peroxisome	cellular_component	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.
GO:0019825	oxygen binding	molecular_function	Binding to oxygen (O2).
GO:0019826	oxygen sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
GO:0019827	stem cell population maintenance	biological_process	The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
GO:0019828	aspartic-type endopeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases.
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
GO:0019834	phospholipase A2 inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of phospholipase A2.
GO:0019835	cytolysis	biological_process	The rupture of cell membranes and the loss of cytoplasm.
GO:0019836	hemolysis by symbiont of host erythrocytes	biological_process	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0019838	growth factor binding	molecular_function	Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.
GO:0019840	isoprenoid binding	molecular_function	Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0019841	retinol binding	molecular_function	Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
GO:0019842	vitamin binding	molecular_function	Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0019843	rRNA binding	molecular_function	Binding to a ribosomal RNA.
GO:0019852	L-ascorbic acid metabolic process	biological_process	The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
GO:0019853	L-ascorbic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
GO:0019854	L-ascorbic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
GO:0019855	calcium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a calcium channel.
GO:0019856	pyrimidine nucleobase biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
GO:0019857	5-methylcytosine metabolic process	biological_process	The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.
GO:0019858	cytosine metabolic process	biological_process	The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
GO:0019859	thymine metabolic process	biological_process	The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
GO:0019860	uracil metabolic process	biological_process	The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
GO:0019862	IgA binding	molecular_function	Binding to an immunoglobulin of an IgA isotype.
GO:0019863	IgE binding	molecular_function	Binding to an immunoglobulin of the IgE isotype.
GO:0019864	IgG binding	molecular_function	Binding to an immunoglobulin of an IgG isotype.
GO:0019865	immunoglobulin binding	molecular_function	Binding to an immunoglobulin.
GO:0019866	organelle inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
GO:0019867	outer membrane	cellular_component	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
GO:0019869	chloride channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a chloride channel.
GO:0019870	potassium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a potassium channel.
GO:0019871	sodium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a sodium channel.
GO:0019872	streptomycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
GO:0019874	6-aminohexanoate-cyclic-dimer hydrolase activity	molecular_function	Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate.
GO:0019875	6-aminohexanoate-dimer hydrolase activity	molecular_function	Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.
GO:0019876	nylon catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.
GO:0019877	diaminopimelate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
GO:0019878	lysine biosynthetic process via aminoadipic acid	biological_process	The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
GO:0019879	peptidyl-thyronine biosynthetic process from peptidyl-tyrosine	biological_process	The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.
GO:0019882	antigen processing and presentation	biological_process	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0019883	antigen processing and presentation of endogenous antigen	biological_process	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.
GO:0019884	antigen processing and presentation of exogenous antigen	biological_process	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
GO:0019887	protein kinase regulator activity	molecular_function	Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
GO:0019888	protein phosphatase regulator activity	molecular_function	Binds to and modulates the activity of a protein phosphatase.
GO:0019889	pteridine metabolic process	biological_process	The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
GO:0019894	kinesin binding	molecular_function	Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
GO:0019896	axonal transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in nerve cell axons.
GO:0019897	extrinsic component of plasma membrane	cellular_component	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0019898	extrinsic component of membrane	cellular_component	The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0019899	enzyme binding	molecular_function	Binding to an enzyme, a protein with catalytic activity.
GO:0019900	kinase binding	molecular_function	Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.
GO:0019901	protein kinase binding	molecular_function	Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
GO:0019902	phosphatase binding	molecular_function	Binding to a phosphatase.
GO:0019903	protein phosphatase binding	molecular_function	Binding to a protein phosphatase.
GO:0019904	protein domain specific binding	molecular_function	Binding to a specific domain of a protein.
GO:0019905	syntaxin binding	molecular_function	Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	cellular_component	A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.
GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	cellular_component	Cyclin-dependent protein kinase (CDK) complex found in the nucleus.
GO:0019909	[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity	molecular_function	Binds to and modulates of the activity of [pyruvate dehydrogenase (lipoamide)] phosphatase.
GO:0019910	mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex	cellular_component	A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.
GO:0019911	structural constituent of myelin sheath	molecular_function	The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.
GO:0019912	cyclin-dependent protein kinase activating kinase activity	molecular_function	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).
GO:0019914	cyclin-dependent protein kinase activating kinase regulator activity	molecular_function	Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.
GO:0019915	lipid storage	biological_process	The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
GO:0019916	peptidyl-D-alanine racemization, direct	biological_process	The racemization of peptidyl-alanine.
GO:0019917	peptidyl-D-alanine racemization via peptidyl-L-serine	biological_process	The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	biological_process	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	biological_process	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.
GO:0019920	peptidyl-1-thioglycine biosynthetic process, internal	biological_process	The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.
GO:0019921	peptidyl-1-thioglycine biosynthetic process, carboxy-terminal	biological_process	The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.
GO:0019926	peptidyl-tryptophan oxidation to tryptophyl quinone	biological_process	The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.
GO:0019927	peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone	biological_process	The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.
GO:0019928	peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid	biological_process	The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.
GO:0019929	peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid	biological_process	The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.
GO:0019930	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid	biological_process	The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.
GO:0019932	second-messenger-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.
GO:0019933	cAMP-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
GO:0019934	cGMP-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
GO:0019935	cyclic-nucleotide-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.
GO:0019939	peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine	biological_process	The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically.
GO:0019941	modification-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
GO:0019948	SUMO activating enzyme activity	molecular_function	Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0019953	sexual reproduction	biological_process	A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).
GO:0019954	asexual reproduction	biological_process	A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells.
GO:0019955	cytokine binding	molecular_function	Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
GO:0019956	chemokine binding	molecular_function	Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0019957	C-C chemokine binding	molecular_function	Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
GO:0019958	C-X-C chemokine binding	molecular_function	Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
GO:0019959	interleukin-8 binding	molecular_function	Binding to interleukin-8.
GO:0019960	C-X3-C chemokine binding	molecular_function	Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
GO:0019961	interferon binding	molecular_function	Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.
GO:0019962	type I interferon binding	molecular_function	Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.
GO:0019964	type II interferon binding	molecular_function	Binding to type II interferon, also known as interferon-gamma.
GO:0019966	interleukin-1 binding	molecular_function	Binding to interleukin-1.
GO:0019969	interleukin-10 binding	molecular_function	Binding to interleukin-10.
GO:0019970	interleukin-11 binding	molecular_function	Binding to interleukin-11.
GO:0019972	interleukin-12 binding	molecular_function	Binding to interleukin-12.
GO:0019973	interleukin-13 binding	molecular_function	Binding to interleukin-13.
GO:0019975	interleukin-17 binding	molecular_function	Binding to a member of the interleukin-17 family of cytokines.
GO:0019976	interleukin-2 binding	molecular_function	Binding to interleukin-2.
GO:0019977	interleukin-21 binding	molecular_function	Binding to interleukin-21.
GO:0019978	interleukin-3 binding	molecular_function	Binding to interleukin-3.
GO:0019979	interleukin-4 binding	molecular_function	Binding to interleukin-4.
GO:0019980	interleukin-5 binding	molecular_function	Binding to interleukin-5.
GO:0019981	interleukin-6 binding	molecular_function	Binding to interleukin-6.
GO:0019982	interleukin-7 binding	molecular_function	Binding to interleukin-7.
GO:0019983	interleukin-9 binding	molecular_function	Binding to interleukin-9.
GO:0019985	translesion synthesis	biological_process	The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
GO:0019988	charged-tRNA amino acid modification	biological_process	The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.
GO:0019990	pteridine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
GO:0019991	septate junction assembly	biological_process	The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
GO:0019992	diacylglycerol binding	molecular_function	Binding to a diacylglycerol, a diester of glycerol and two fatty acids.
GO:0020002	host cell plasma membrane	cellular_component	The plasma membrane surrounding a host cell.
GO:0020003	symbiont-containing vacuole	cellular_component	Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.
GO:0020004	symbiont-containing vacuolar space	cellular_component	The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane.
GO:0020005	symbiont-containing vacuole membrane	cellular_component	The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.
GO:0020006	symbiont-containing vacuolar membrane network	cellular_component	Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.
GO:0020007	apical complex	cellular_component	A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.
GO:0020008	rhoptry	cellular_component	A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.
GO:0020009	microneme	cellular_component	A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.
GO:0020010	conoid	cellular_component	A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.
GO:0020011	apicoplast	cellular_component	The plastid organelle found in apicomplexans.
GO:0020013	modulation by symbiont of host erythrocyte aggregation	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.
GO:0020014	schizogony	biological_process	Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.
GO:0020015	glycosome	cellular_component	A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
GO:0020016	ciliary pocket	cellular_component	Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.
GO:0020018	ciliary pocket membrane	cellular_component	That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).
GO:0020020	food vacuole	cellular_component	Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.
GO:0020022	acidocalcisome	cellular_component	An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
GO:0020023	kinetoplast	cellular_component	A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
GO:0020025	subpellicular microtubule	cellular_component	Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.
GO:0020026	merozoite dense granule	cellular_component	Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.
GO:0020027	hemoglobin metabolic process	biological_process	The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
GO:0020028	endocytic hemoglobin import into cell	biological_process	The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.
GO:0020030	infected host cell surface knob	cellular_component	Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.
GO:0020031	polar ring of apical complex	cellular_component	An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.
GO:0020032	basal ring of apical complex	cellular_component	An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.
GO:0020033	antigenic variation	biological_process	Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
GO:0020035	adhesion of symbiont to microvasculature	biological_process	The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.
GO:0020036	Maurer's cleft	cellular_component	A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.
GO:0020037	heme binding	molecular_function	Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0020038	subpellicular network	cellular_component	A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.
GO:0020039	pellicle	cellular_component	The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.
GO:0021501	prechordal plate formation	biological_process	The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.
GO:0021502	neural fold elevation formation	biological_process	The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.
GO:0021503	neural fold bending	biological_process	The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
GO:0021504	neural fold hinge point formation	biological_process	The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.
GO:0021505	neural fold folding	biological_process	The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.
GO:0021506	anterior neuropore closure	biological_process	The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.
GO:0021507	posterior neuropore closure	biological_process	The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.
GO:0021508	floor plate formation	biological_process	The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.
GO:0021509	roof plate formation	biological_process	The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.
GO:0021510	spinal cord development	biological_process	The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
GO:0021511	spinal cord patterning	biological_process	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.
GO:0021512	spinal cord anterior/posterior patterning	biological_process	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.
GO:0021513	spinal cord dorsal/ventral patterning	biological_process	The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
GO:0021514	ventral spinal cord interneuron differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021515	cell differentiation in spinal cord	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021516	dorsal spinal cord development	biological_process	The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.
GO:0021517	ventral spinal cord development	biological_process	The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.
GO:0021518	spinal cord commissural neuron specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.
GO:0021519	spinal cord association neuron specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.
GO:0021520	spinal cord motor neuron cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
GO:0021521	ventral spinal cord interneuron specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
GO:0021522	spinal cord motor neuron differentiation	biological_process	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021523	somatic motor neuron differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021524	visceral motor neuron differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021525	lateral motor column neuron differentiation	biological_process	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021526	medial motor column neuron differentiation	biological_process	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021527	spinal cord association neuron differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021528	commissural neuron differentiation in spinal cord	biological_process	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021529	spinal cord oligodendrocyte cell differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021530	spinal cord oligodendrocyte cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.
GO:0021531	spinal cord radial glial cell differentiation	biological_process	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021532	neural tube patterning	biological_process	The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.
GO:0021533	cell differentiation in hindbrain	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021534	cell proliferation in hindbrain	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
GO:0021535	cell migration in hindbrain	biological_process	The orderly movement of a cell that will reside in the hindbrain.
GO:0021536	diencephalon development	biological_process	The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
GO:0021537	telencephalon development	biological_process	The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
GO:0021538	epithalamus development	biological_process	The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.
GO:0021539	subthalamus development	biological_process	The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.
GO:0021540	corpus callosum morphogenesis	biological_process	The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.
GO:0021541	ammon gyrus development	biological_process	The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.
GO:0021542	dentate gyrus development	biological_process	The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
GO:0021543	pallium development	biological_process	The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.
GO:0021544	subpallium development	biological_process	The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.
GO:0021545	cranial nerve development	biological_process	The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
GO:0021546	rhombomere development	biological_process	The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
GO:0021547	midbrain-hindbrain boundary initiation	biological_process	The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0021548	pons development	biological_process	The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
GO:0021549	cerebellum development	biological_process	The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
GO:0021550	medulla oblongata development	biological_process	The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
GO:0021551	central nervous system morphogenesis	biological_process	The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GO:0021552	midbrain-hindbrain boundary structural organization	biological_process	The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0021553	olfactory nerve development	biological_process	The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
GO:0021554	optic nerve development	biological_process	The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
GO:0021555	midbrain-hindbrain boundary morphogenesis	biological_process	The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0021556	central nervous system formation	biological_process	The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GO:0021557	oculomotor nerve development	biological_process	The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
GO:0021558	trochlear nerve development	biological_process	The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
GO:0021559	trigeminal nerve development	biological_process	The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
GO:0021560	abducens nerve development	biological_process	The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
GO:0021561	facial nerve development	biological_process	The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
GO:0021562	vestibulocochlear nerve development	biological_process	The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
GO:0021563	glossopharyngeal nerve development	biological_process	Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
GO:0021564	vagus nerve development	biological_process	The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
GO:0021565	accessory nerve development	biological_process	The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
GO:0021566	hypoglossal nerve development	biological_process	The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
GO:0021567	rhombomere 1 development	biological_process	The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021568	rhombomere 2 development	biological_process	The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021569	rhombomere 3 development	biological_process	The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021570	rhombomere 4 development	biological_process	The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021571	rhombomere 5 development	biological_process	The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021572	rhombomere 6 development	biological_process	The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021573	rhombomere 7 development	biological_process	The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021574	rhombomere 8 development	biological_process	The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021575	hindbrain morphogenesis	biological_process	The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
GO:0021576	hindbrain formation	biological_process	The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
GO:0021577	hindbrain structural organization	biological_process	The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
GO:0021578	hindbrain maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
GO:0021579	medulla oblongata morphogenesis	biological_process	The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
GO:0021580	medulla oblongata formation	biological_process	The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
GO:0021581	medulla oblongata structural organization	biological_process	The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
GO:0021582	medulla oblongata maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
GO:0021583	pons morphogenesis	biological_process	The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
GO:0021584	pons formation	biological_process	The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
GO:0021585	pons structural organization	biological_process	The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
GO:0021586	pons maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
GO:0021587	cerebellum morphogenesis	biological_process	The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
GO:0021588	cerebellum formation	biological_process	The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
GO:0021589	cerebellum structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
GO:0021590	cerebellum maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
GO:0021591	ventricular system development	biological_process	The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.
GO:0021592	fourth ventricle development	biological_process	The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.
GO:0021593	rhombomere morphogenesis	biological_process	The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
GO:0021594	rhombomere formation	biological_process	The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
GO:0021595	rhombomere structural organization	biological_process	The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
GO:0021597	central nervous system structural organization	biological_process	The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GO:0021598	abducens nerve morphogenesis	biological_process	The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
GO:0021599	abducens nerve formation	biological_process	The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
GO:0021600	abducens nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
GO:0021601	abducens nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
GO:0021602	cranial nerve morphogenesis	biological_process	The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
GO:0021603	cranial nerve formation	biological_process	The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
GO:0021604	cranial nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
GO:0021605	cranial nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
GO:0021606	accessory nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
GO:0021607	accessory nerve morphogenesis	biological_process	The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
GO:0021608	accessory nerve formation	biological_process	The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
GO:0021609	accessory nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
GO:0021610	facial nerve morphogenesis	biological_process	The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
GO:0021611	facial nerve formation	biological_process	The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
GO:0021612	facial nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
GO:0021613	facial nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
GO:0021614	glossopharyngeal nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
GO:0021615	glossopharyngeal nerve morphogenesis	biological_process	The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
GO:0021616	glossopharyngeal nerve formation	biological_process	The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
GO:0021617	glossopharyngeal nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
GO:0021618	hypoglossal nerve morphogenesis	biological_process	The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
GO:0021619	hypoglossal nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
GO:0021620	hypoglossal nerve formation	biological_process	The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
GO:0021621	hypoglossal nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
GO:0021622	oculomotor nerve morphogenesis	biological_process	The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
GO:0021623	oculomotor nerve formation	biological_process	The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
GO:0021624	oculomotor nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
GO:0021625	oculomotor nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
GO:0021626	central nervous system maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
GO:0021627	olfactory nerve morphogenesis	biological_process	The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
GO:0021628	olfactory nerve formation	biological_process	The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
GO:0021629	olfactory nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
GO:0021630	olfactory nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
GO:0021631	optic nerve morphogenesis	biological_process	The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
GO:0021632	optic nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
GO:0021633	optic nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
GO:0021634	optic nerve formation	biological_process	The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
GO:0021635	trigeminal nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
GO:0021636	trigeminal nerve morphogenesis	biological_process	The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
GO:0021637	trigeminal nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
GO:0021638	trigeminal nerve formation	biological_process	The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
GO:0021639	trochlear nerve morphogenesis	biological_process	The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
GO:0021640	trochlear nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
GO:0021641	trochlear nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
GO:0021642	trochlear nerve formation	biological_process	The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
GO:0021643	vagus nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
GO:0021644	vagus nerve morphogenesis	biological_process	The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
GO:0021645	vagus nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
GO:0021646	vagus nerve formation	biological_process	The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
GO:0021647	vestibulocochlear nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
GO:0021648	vestibulocochlear nerve morphogenesis	biological_process	The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
GO:0021649	vestibulocochlear nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
GO:0021650	vestibulocochlear nerve formation	biological_process	The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
GO:0021651	rhombomere 1 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021652	rhombomere 1 formation	biological_process	The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021653	rhombomere 1 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021654	rhombomere boundary formation	biological_process	The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021655	rhombomere 2 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021656	rhombomere 2 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021657	rhombomere 2 formation	biological_process	The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021658	rhombomere 3 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021659	rhombomere 3 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021660	rhombomere 3 formation	biological_process	The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021661	rhombomere 4 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021662	rhombomere 4 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021663	rhombomere 4 formation	biological_process	The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021664	rhombomere 5 morphogenesis	biological_process	The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021665	rhombomere 5 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021666	rhombomere 5 formation	biological_process	The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021667	rhombomere 6 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021668	rhombomere 6 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021669	rhombomere 6 formation	biological_process	The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021670	lateral ventricle development	biological_process	The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.
GO:0021671	rhombomere 7 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021672	rhombomere 7 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021673	rhombomere 7 formation	biological_process	The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021674	rhombomere 8 morphogenesis	biological_process	The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021675	nerve development	biological_process	The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.
GO:0021676	rhombomere 8 structural organization	biological_process	The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
GO:0021677	rhombomere 8 formation	biological_process	The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
GO:0021678	third ventricle development	biological_process	The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.
GO:0021679	cerebellar molecular layer development	biological_process	The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
GO:0021680	cerebellar Purkinje cell layer development	biological_process	The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
GO:0021681	cerebellar granular layer development	biological_process	The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
GO:0021682	nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.
GO:0021683	cerebellar granular layer morphogenesis	biological_process	The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
GO:0021684	cerebellar granular layer formation	biological_process	The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
GO:0021685	cerebellar granular layer structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
GO:0021686	cerebellar granular layer maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
GO:0021687	cerebellar molecular layer morphogenesis	biological_process	The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
GO:0021688	cerebellar molecular layer formation	biological_process	The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
GO:0021689	cerebellar molecular layer structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
GO:0021690	cerebellar molecular layer maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
GO:0021691	cerebellar Purkinje cell layer maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
GO:0021692	cerebellar Purkinje cell layer morphogenesis	biological_process	The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
GO:0021693	cerebellar Purkinje cell layer structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
GO:0021694	cerebellar Purkinje cell layer formation	biological_process	The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
GO:0021695	cerebellar cortex development	biological_process	The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
GO:0021696	cerebellar cortex morphogenesis	biological_process	The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
GO:0021697	cerebellar cortex formation	biological_process	The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
GO:0021698	cerebellar cortex structural organization	biological_process	The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
GO:0021699	cerebellar cortex maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
GO:0021700	developmental maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
GO:0021701	cerebellar Golgi cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021702	cerebellar Purkinje cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
GO:0021703	locus ceruleus development	biological_process	The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
GO:0021704	locus ceruleus morphogenesis	biological_process	The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
GO:0021705	locus ceruleus formation	biological_process	The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
GO:0021706	locus ceruleus maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
GO:0021707	cerebellar granule cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
GO:0021708	Lugaro cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021709	cerebellar basket cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021710	cerebellar stellate cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021711	cerebellar unipolar brush cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.
GO:0021712	candelabrum cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021713	inferior olivary nucleus development	biological_process	The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
GO:0021714	inferior olivary nucleus morphogenesis	biological_process	The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
GO:0021715	inferior olivary nucleus formation	biological_process	The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
GO:0021716	inferior olivary nucleus structural organization	biological_process	The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
GO:0021717	inferior olivary nucleus maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
GO:0021718	superior olivary nucleus development	biological_process	The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
GO:0021719	superior olivary nucleus morphogenesis	biological_process	The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
GO:0021720	superior olivary nucleus formation	biological_process	The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
GO:0021721	superior olivary nucleus structural organization	biological_process	The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
GO:0021722	superior olivary nucleus maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
GO:0021723	medullary reticular formation development	biological_process	The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.
GO:0021724	inferior raphe nucleus development	biological_process	The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.
GO:0021725	superior raphe nucleus development	biological_process	The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.
GO:0021726	lateral reticular nucleus development	biological_process	The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.
GO:0021727	intermediate reticular formation development	biological_process	The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.
GO:0021728	inferior reticular formation development	biological_process	The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.
GO:0021729	superior reticular formation development	biological_process	The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.
GO:0021730	trigeminal sensory nucleus development	biological_process	The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.
GO:0021731	trigeminal motor nucleus development	biological_process	The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.
GO:0021732	midbrain-hindbrain boundary maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0021735	dentate nucleus development	biological_process	The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.
GO:0021736	globose nucleus development	biological_process	The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.
GO:0021737	emboliform nucleus development	biological_process	The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.
GO:0021738	fastigial nucleus development	biological_process	The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.
GO:0021739	mesencephalic trigeminal nucleus development	biological_process	The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.
GO:0021740	principal sensory nucleus of trigeminal nerve development	biological_process	The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.
GO:0021741	spinal trigeminal nucleus development	biological_process	The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.
GO:0021742	abducens nucleus development	biological_process	The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.
GO:0021743	hypoglossal nucleus development	biological_process	The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.
GO:0021744	dorsal motor nucleus of vagus nerve development	biological_process	The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.
GO:0021745	nucleus ambiguus development	biological_process	The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.
GO:0021746	solitary nucleus development	biological_process	The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.
GO:0021747	cochlear nucleus development	biological_process	The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.
GO:0021748	dorsal cochlear nucleus development	biological_process	The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.
GO:0021749	ventral cochlear nucleus development	biological_process	The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.
GO:0021750	vestibular nucleus development	biological_process	The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.
GO:0021751	salivary nucleus development	biological_process	The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.
GO:0021752	inferior salivary nucleus development	biological_process	The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.
GO:0021753	superior salivary nucleus development	biological_process	The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.
GO:0021754	facial nucleus development	biological_process	The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.
GO:0021755	eurydendroid cell differentiation	biological_process	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.
GO:0021756	striatum development	biological_process	The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.
GO:0021757	caudate nucleus development	biological_process	The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.
GO:0021758	putamen development	biological_process	The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.
GO:0021759	globus pallidus development	biological_process	The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.
GO:0021761	limbic system development	biological_process	The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.
GO:0021762	substantia nigra development	biological_process	The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).
GO:0021763	subthalamic nucleus development	biological_process	The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.
GO:0021764	amygdala development	biological_process	The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.
GO:0021765	cingulate gyrus development	biological_process	The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.
GO:0021766	hippocampus development	biological_process	The progression of the hippocampus over time from its initial formation until its mature state.
GO:0021767	mammillary body development	biological_process	The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.
GO:0021768	nucleus accumbens development	biological_process	The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.
GO:0021769	orbitofrontal cortex development	biological_process	The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.
GO:0021770	parahippocampal gyrus development	biological_process	The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.
GO:0021771	lateral geniculate nucleus development	biological_process	The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.
GO:0021772	olfactory bulb development	biological_process	The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.
GO:0021773	striatal medium spiny neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.
GO:0021774	retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification	biological_process	The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	biological_process	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	biological_process	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
GO:0021778	oligodendrocyte cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0021779	oligodendrocyte cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.
GO:0021780	glial cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0021781	glial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.
GO:0021782	glial cell development	biological_process	The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0021783	preganglionic parasympathetic fiber development	biological_process	The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.
GO:0021784	postganglionic parasympathetic fiber development	biological_process	The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
GO:0021785	branchiomotor neuron axon guidance	biological_process	The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021786	branchiomotor neuron axon guidance in neural tube	biological_process	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021787	chemorepulsion of branchiomotor neuron axon in neural tube	biological_process	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021788	chemoattraction of branchiomotor neuron axon in neural tube	biological_process	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021789	branchiomotor neuron axon guidance in branchial arch mesenchyme	biological_process	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021790	chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme	biological_process	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021791	chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme	biological_process	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021792	chemoattraction of branchiomotor axon	biological_process	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021793	chemorepulsion of branchiomotor axon	biological_process	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
GO:0021794	thalamus development	biological_process	The process in which the thalamus changes over time, from its initial formation to its mature state.
GO:0021795	cerebral cortex cell migration	biological_process	The orderly movement of cells from one site to another in the cerebral cortex.
GO:0021796	cerebral cortex regionalization	biological_process	The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.
GO:0021797	forebrain anterior/posterior pattern specification	biological_process	The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.
GO:0021798	forebrain dorsal/ventral pattern formation	biological_process	The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.
GO:0021799	cerebral cortex radially oriented cell migration	biological_process	The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
GO:0021800	cerebral cortex tangential migration	biological_process	The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
GO:0021801	cerebral cortex radial glia-guided migration	biological_process	The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.
GO:0021802	somal translocation	biological_process	The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.
GO:0021803	extension of leading cell process to pial surface	biological_process	The extension of a long process to the pial surface as a cell leaves the ventricular zone.
GO:0021804	negative regulation of cell adhesion in ventricular zone	biological_process	The process that results in the loss of attachments of a cell in the ventricular zone.
GO:0021805	cell movement involved in somal translocation	biological_process	The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.
GO:0021806	initiation of movement involved in cerebral cortex radial glia guided migration	biological_process	The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.
GO:0021807	motogenic signaling initiating cell movement in cerebral cortex	biological_process	The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.
GO:0021808	cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration	biological_process	The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.
GO:0021809	neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	biological_process	Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration.
GO:0021810	neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	biological_process	Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration.
GO:0021811	growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration	biological_process	Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.
GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration	biological_process	The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
GO:0021813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	biological_process	The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.
GO:0021814	cell motility involved in cerebral cortex radial glia guided migration	biological_process	The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.
GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	biological_process	Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.
GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	biological_process	The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.
GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	biological_process	The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.
GO:0021818	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration	biological_process	The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
GO:0021819	layer formation in cerebral cortex	biological_process	The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.
GO:0021820	extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration	biological_process	The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.
GO:0021821	negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination	biological_process	The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
GO:0021822	negative regulation of cell motility involved in cerebral cortex radial glia guided migration	biological_process	The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.
GO:0021823	cerebral cortex tangential migration using cell-cell interactions	biological_process	The process in which neurons interact with each other to promote migration along a tangential plane.
GO:0021824	cerebral cortex tangential migration using cell-axon interactions	biological_process	The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.
GO:0021825	substrate-dependent cerebral cortex tangential migration	biological_process	The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.
GO:0021826	substrate-independent telencephalic tangential migration	biological_process	The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.
GO:0021827	postnatal olfactory bulb interneuron migration	biological_process	The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.
GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	biological_process	The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.
GO:0021829	oligodendrocyte cell migration from the subpallium to the cortex	biological_process	The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.
GO:0021830	interneuron migration from the subpallium to the cortex	biological_process	The directed movement of interneurons from the subpallium to the cortex during forebrain development.
GO:0021831	embryonic olfactory bulb interneuron precursor migration	biological_process	The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.
GO:0021832	cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions	biological_process	The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.
GO:0021833	cell-matrix adhesion involved in tangential migration using cell-cell interactions	biological_process	The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.
GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration	biological_process	The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.
GO:0021835	chemoattraction involved in embryonic olfactory bulb interneuron precursor migration	biological_process	The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	biological_process	The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	biological_process	The signaling that results in the stimulation of cell movement in the rostral migratory stream.
GO:0021838	motogenic signaling involved in interneuron migration from the subpallium to the cortex	biological_process	The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.
GO:0021839	interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex	biological_process	The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.
GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex	biological_process	The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.
GO:0021841	chemoattraction involved in interneuron migration from the subpallium to the cortex	biological_process	The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex.
GO:0021842	chemorepulsion involved in interneuron migration from the subpallium to the cortex	biological_process	The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.
GO:0021843	substrate-independent telencephalic tangential interneuron migration	biological_process	The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.
GO:0021844	interneuron sorting involved in substrate-independent cerebral cortex tangential migration	biological_process	The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.
GO:0021845	neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration	biological_process	The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.
GO:0021846	cell proliferation in forebrain	biological_process	The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
GO:0021847	ventricular zone neuroblast division	biological_process	The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.
GO:0021848	neuroblast division in subpallium	biological_process	The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.
GO:0021849	neuroblast division in subventricular zone	biological_process	The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.
GO:0021850	subpallium glioblast cell division	biological_process	The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.
GO:0021851	neuroblast division in dorsal lateral ganglionic eminence	biological_process	The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.
GO:0021852	pyramidal neuron migration to cerebral cortex	biological_process	The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.
GO:0021853	cerebral cortex GABAergic interneuron migration	biological_process	The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
GO:0021854	hypothalamus development	biological_process	The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.
GO:0021855	hypothalamus cell migration	biological_process	The directed movement of a cell into the hypothalamus region of the forebrain.
GO:0021856	hypothalamic tangential migration using cell-axon interactions	biological_process	The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.
GO:0021858	GABAergic neuron differentiation in basal ganglia	biological_process	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.
GO:0021859	pyramidal neuron differentiation	biological_process	The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.
GO:0021860	pyramidal neuron development	biological_process	The progression of a pyramidal neuron from its initial formation to its mature state.
GO:0021861	forebrain radial glial cell differentiation	biological_process	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021862	early neuron differentiation in forebrain	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021863	forebrain neuroblast differentiation	biological_process	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0021869	forebrain ventricular zone progenitor cell division	biological_process	The mitotic division of a basal progenitor giving rise to two neurons.
GO:0021870	Cajal-Retzius cell differentiation	biological_process	The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.
GO:0021871	forebrain regionalization	biological_process	The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.
GO:0021872	forebrain generation of neurons	biological_process	The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.
GO:0021873	forebrain neuroblast division	biological_process	The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.
GO:0021874	Wnt signaling pathway involved in forebrain neuroblast division	biological_process	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.
GO:0021875	fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.
GO:0021876	Notch signaling pathway involved in forebrain neuroblast division	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.
GO:0021877	forebrain neuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.
GO:0021878	forebrain astrocyte fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.
GO:0021879	forebrain neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.
GO:0021880	Notch signaling pathway involved in forebrain neuron fate commitment	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
GO:0021881	Wnt-activated signaling pathway involved in forebrain neuron fate commitment	biological_process	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.
GO:0021884	forebrain neuron development	biological_process	The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.
GO:0021885	forebrain cell migration	biological_process	The orderly movement of a cell from one site to another at least one of which is located in the forebrain.
GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.
GO:0021887	hypothalamus gonadotrophin-releasing hormone neuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.
GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron development	biological_process	The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.
GO:0021889	olfactory bulb interneuron differentiation	biological_process	The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.
GO:0021890	olfactory bulb interneuron fate commitment	biological_process	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.
GO:0021891	olfactory bulb interneuron development	biological_process	The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.
GO:0021892	cerebral cortex GABAergic interneuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	biological_process	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.
GO:0021894	cerebral cortex GABAergic interneuron development	biological_process	The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.
GO:0021895	cerebral cortex neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
GO:0021896	forebrain astrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
GO:0021897	forebrain astrocyte development	biological_process	The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	biological_process	The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.
GO:0021899	fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
GO:0021900	ventricular zone cell fate commitment	biological_process	The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.
GO:0021901	early neuron fate commitment in forebrain	biological_process	The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	biological_process	The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.
GO:0021903	rostrocaudal neural tube patterning	biological_process	The process in which the neural tube is divided into specific regions along the rostrocaudal axis.
GO:0021904	dorsal/ventral neural tube patterning	biological_process	The process in which the neural tube is regionalized in the dorsoventral axis.
GO:0021905	forebrain-midbrain boundary formation	biological_process	The process whose specific outcome is the creation of the forebrain-midbrain boundary.
GO:0021906	hindbrain-spinal cord boundary formation	biological_process	The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.
GO:0021907	fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
GO:0021908	retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
GO:0021911	retinoic acid metabolic process in spinal cord anterior-posterior patterning	biological_process	The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
GO:0021915	neural tube development	biological_process	The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
GO:0021916	inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors	biological_process	Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.
GO:0021917	somatic motor neuron fate commitment	biological_process	The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.
GO:0021921	regulation of cell proliferation in dorsal spinal cord	biological_process	The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.
GO:0021922	Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord	biological_process	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.
GO:0021923	cell proliferation in hindbrain ventricular zone	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.
GO:0021924	cell proliferation in external granule layer	biological_process	The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.
GO:0021925	cerebellar Purkinje cell precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
GO:0021926	Golgi cell precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021927	deep nuclear neuron precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.
GO:0021928	basket cell precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021929	stellate cell precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
GO:0021930	cerebellar granule cell precursor proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
GO:0021931	rostral hindbrain neuronal precursor cell proliferation	biological_process	The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.
GO:0021932	hindbrain radial glia guided cell migration	biological_process	The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.
GO:0021933	radial glia guided migration of cerebellar granule cell	biological_process	The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.
GO:0021934	hindbrain tangential cell migration	biological_process	The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.
GO:0021935	cerebellar granule cell precursor tangential migration	biological_process	The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.
GO:0021936	regulation of cerebellar granule cell precursor proliferation	biological_process	The process that modulates the frequency, rate or extent of granule cell precursor proliferation.
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	biological_process	The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation.
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.
GO:0021939	extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation	biological_process	The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	biological_process	The process that activates or increases the rate or extent of granule cell precursor proliferation.
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	biological_process	The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.
GO:0021942	radial glia guided migration of Purkinje cell	biological_process	The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.
GO:0021943	formation of radial glial scaffolds	biological_process	The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.
GO:0021944	neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration	biological_process	The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.
GO:0021945	positive regulation of cerebellar granule cell migration by calcium	biological_process	The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.
GO:0021946	deep nuclear neuron cell migration	biological_process	The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.
GO:0021947	outward migration of deep nuclear neurons	biological_process	The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.
GO:0021948	inward migration of deep nuclear neurons	biological_process	The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.
GO:0021949	brainstem precerebellar neuron precursor migration	biological_process	The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.
GO:0021950	chemorepulsion involved in precerebellar neuron migration	biological_process	The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.
GO:0021951	chemoattraction involved in precerebellar neuron migration	biological_process	The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration.
GO:0021952	central nervous system projection neuron axonogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
GO:0021953	central nervous system neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.
GO:0021954	central nervous system neuron development	biological_process	The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
GO:0021955	central nervous system neuron axonogenesis	biological_process	Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.
GO:0021956	central nervous system interneuron axonogenesis	biological_process	Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.
GO:0021957	corticospinal tract morphogenesis	biological_process	Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.
GO:0021958	gracilis tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.
GO:0021959	cuneatus tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.
GO:0021960	anterior commissure morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.
GO:0021961	posterior commissure morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.
GO:0021962	vestibulospinal tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.
GO:0021963	spinothalamic tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.
GO:0021964	rubrospinal tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.
GO:0021965	spinal cord ventral commissure morphogenesis	biological_process	The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.
GO:0021966	corticospinal neuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.
GO:0021967	corticospinal neuron axon guidance through the cerebral cortex	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.
GO:0021968	corticospinal neuron axon guidance through the internal capsule	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.
GO:0021969	corticospinal neuron axon guidance through the cerebral peduncle	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.
GO:0021970	corticospinal neuron axon guidance through the basilar pons	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.
GO:0021971	corticospinal neuron axon guidance through the medullary pyramid	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.
GO:0021972	corticospinal neuron axon guidance through spinal cord	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.
GO:0021973	corticospinal neuron axon decussation	biological_process	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.
GO:0021974	trigeminothalamic tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.
GO:0021975	pons reticulospinal tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.
GO:0021976	medulla reticulospinal tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.
GO:0021977	tectospinal tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.
GO:0021978	telencephalon regionalization	biological_process	The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.
GO:0021979	hypothalamus cell differentiation	biological_process	The differentiation of cells that will contribute to the structure and function of the hypothalamus.
GO:0021980	subpallium cell migration	biological_process	The orderly movement of cells from one site to another in the subpallium.
GO:0021981	subpallium radially oriented migration	biological_process	The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
GO:0021982	pineal gland development	biological_process	The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.
GO:0021983	pituitary gland development	biological_process	The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
GO:0021984	adenohypophysis development	biological_process	The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
GO:0021985	neurohypophysis development	biological_process	The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
GO:0021986	habenula development	biological_process	The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.
GO:0021987	cerebral cortex development	biological_process	The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
GO:0021988	olfactory lobe development	biological_process	The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.
GO:0021989	olfactory cortex development	biological_process	The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.
GO:0021990	neural plate formation	biological_process	The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
GO:0021991	neural plate thickening	biological_process	The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.
GO:0021992	cell proliferation involved in neural plate elongation	biological_process	The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.
GO:0021993	initiation of neural tube closure	biological_process	The process in which closure points are established at multiple points and along the neural rostrocaudal axis.
GO:0021994	progression of neural tube closure	biological_process	The process in which the neural folds are fused extending from the initial closure points.
GO:0021995	neuropore closure	biological_process	The process of joining together the neural folds at either end of the neural tube.
GO:0021996	lamina terminalis formation	biological_process	The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.
GO:0021997	neural plate axis specification	biological_process	The pattern specification process in which the axes of the nervous system are established.
GO:0021998	neural plate mediolateral regionalization	biological_process	The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.
GO:0021999	neural plate anterior/posterior regionalization	biological_process	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.
GO:0022000	forebrain induction by the anterior neural ridge	biological_process	The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.
GO:0022001	negative regulation of anterior neural cell fate commitment of the neural plate	biological_process	Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway	biological_process	The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.
GO:0022003	negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway	biological_process	The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
GO:0022004	midbrain-hindbrain boundary maturation during brain development	biological_process	A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0022005	midbrain-hindbrain boundary maturation during neural plate development	biological_process	A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
GO:0022006	zona limitans intrathalamica formation	biological_process	The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.
GO:0022007	convergent extension involved in neural plate elongation	biological_process	The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.
GO:0022008	neurogenesis	biological_process	Generation of cells within the nervous system.
GO:0022009	central nervous system vasculogenesis	biological_process	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.
GO:0022010	central nervous system myelination	biological_process	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
GO:0022011	myelination in peripheral nervous system	biological_process	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
GO:0022012	subpallium cell proliferation in forebrain	biological_process	The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.
GO:0022013	pallium cell proliferation in forebrain	biological_process	The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.
GO:0022015	radial glial cell division in pallium	biological_process	The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
GO:0022016	pallium glioblast division	biological_process	The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.
GO:0022017	neuroblast division in pallium	biological_process	The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.
GO:0022018	lateral ganglionic eminence cell proliferation	biological_process	The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.
GO:0022019	dorsal lateral ganglionic eminence cell proliferation	biological_process	The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.
GO:0022020	medial ganglionic eminence cell proliferation	biological_process	The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.
GO:0022021	caudal ganglionic eminence cell proliferation	biological_process	The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.
GO:0022022	septal cell proliferation	biological_process	The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.
GO:0022023	radial glial cell fate commitment in forebrain	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.
GO:0022025	leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment	biological_process	The series of molecular signals initiated by the binding of leukemia inhibitory factor to its receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
GO:0022026	epidermal growth factor signaling pathway involved in forebrain neuron fate commitment	biological_process	The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
GO:0022027	interkinetic nuclear migration	biological_process	The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	biological_process	The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
GO:0022029	telencephalon cell migration	biological_process	The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.
GO:0022030	telencephalon glial cell migration	biological_process	The orderly movement of glial cells through the telencephalon.
GO:0022031	telencephalon astrocyte cell migration	biological_process	The orderly movement of an astrocyte cell through the telencephalon.
GO:0022032	telencephalon oligodendrocyte cell migration	biological_process	The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.
GO:0022033	telencephalon microglial cell migration	biological_process	The orderly movement of microglial cells through the telencephalon.
GO:0022034	rhombomere cell proliferation	biological_process	The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.
GO:0022035	rhombomere cell migration	biological_process	The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
GO:0022036	rhombomere cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.
GO:0022037	metencephalon development	biological_process	The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.
GO:0022038	corpus callosum development	biological_process	The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.
GO:0022400	regulation of rhodopsin mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
GO:0022401	negative adaptation of signaling pathway	biological_process	The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
GO:0022402	cell cycle process	biological_process	The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GO:0022403	cell cycle phase	biological_process	One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GO:0022404	molting cycle process	biological_process	A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.
GO:0022405	hair cycle process	biological_process	A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
GO:0022406	membrane docking	biological_process	The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
GO:0022407	regulation of cell-cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
GO:0022408	negative regulation of cell-cell adhesion	biological_process	Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
GO:0022409	positive regulation of cell-cell adhesion	biological_process	Any process that activates or increases the rate or extent of cell adhesion to another cell.
GO:0022410	circadian sleep/wake cycle process	biological_process	A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
GO:0022411	cellular component disassembly	biological_process	A cellular process that results in the breakdown of a cellular component.
GO:0022412	cellular process involved in reproduction in multicellular organism	biological_process	A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.
GO:0022413	reproductive process in single-celled organism	biological_process	A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.
GO:0022414	reproductive process	biological_process	A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GO:0022416	chaeta development	biological_process	The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
GO:0022417	protein maturation by protein folding	biological_process	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.
GO:0022600	digestive system process	biological_process	A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0022601	menstrual cycle phase	biological_process	The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.
GO:0022602	ovulation cycle process	biological_process	A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
GO:0022603	regulation of anatomical structure morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
GO:0022604	regulation of cell morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
GO:0022605	mammalian oogenesis stage	biological_process	A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.
GO:0022606	establishment of proximal/distal cell polarity	biological_process	The specification and formation of the polarity of a cell along its proximal/distal axis.
GO:0022607	cellular component assembly	biological_process	The aggregation, arrangement and bonding together of a cellular component.
GO:0022608	multicellular organism adhesion	biological_process	The attachment of a multicellular organism to a substrate or other organism.
GO:0022609	multicellular organism adhesion to substrate	biological_process	The attachment of a multicellular organism to a surface or material.
GO:0022611	dormancy process	biological_process	A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.
GO:0022612	gland morphogenesis	biological_process	The process in which the anatomical structures of a gland are generated and organized.
GO:0022613	ribonucleoprotein complex biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.
GO:0022614	membrane to membrane docking	biological_process	The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.
GO:0022615	protein to membrane docking	biological_process	The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.
GO:0022616	DNA strand elongation	biological_process	The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
GO:0022617	extracellular matrix disassembly	biological_process	A process that results in the breakdown of the extracellular matrix.
GO:0022618	protein-RNA complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
GO:0022619	generative cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.
GO:0022620	microgametophyte vegetative cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube.
GO:0022622	root system development	biological_process	The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.
GO:0022623	proteasome-activating nucleotidase complex	cellular_component	A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.
GO:0022624	proteasome accessory complex	cellular_component	A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.
GO:0022625	cytosolic large ribosomal subunit	cellular_component	The large subunit of a ribosome located in the cytosol.
GO:0022626	cytosolic ribosome	cellular_component	A ribosome located in the cytosol.
GO:0022627	cytosolic small ribosomal subunit	cellular_component	The small subunit of a ribosome located in the cytosol.
GO:0022628	chloroplast large ribosomal subunit	cellular_component	The large subunit of a ribosome contained within a chloroplast.
GO:0022629	chloroplast small ribosomal subunit	cellular_component	The small subunit of a ribosome contained within a chloroplast.
GO:0022803	passive transmembrane transporter activity	molecular_function	Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.
GO:0022804	active transmembrane transporter activity	molecular_function	Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GO:0022809	mobile ion carrier activity	molecular_function	Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.
GO:0022810	membrane potential driven uniporter activity	molecular_function	Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0022818	sodium ion uniporter activity	molecular_function	Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0022819	potassium ion uniporter activity	molecular_function	Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0022821	solute:potassium antiporter activity	molecular_function	Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
GO:0022824	transmitter-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
GO:0022828	phosphorylation-gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.
GO:0022829	wide pore channel activity	molecular_function	Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
GO:0022831	narrow pore, gated channel activity	molecular_function	Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.
GO:0022832	voltage-gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0022834	ligand-gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0022835	transmitter-gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
GO:0022836	gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
GO:0022839	monoatomic ion gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
GO:0022840	leak channel activity	molecular_function	Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
GO:0022841	potassium ion leak channel activity	molecular_function	Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
GO:0022842	narrow pore channel activity	molecular_function	Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.
GO:0022843	voltage-gated monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	molecular_function	Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
GO:0022849	glutamate-gated calcium ion channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
GO:0022850	serotonin-gated monoatomic cation-selective channel activity	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.
GO:0022851	GABA-gated chloride ion channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.
GO:0022852	glycine-gated chloride ion channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
GO:0022853	active monoatomic ion transmembrane transporter activity	molecular_function	Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
GO:0022855	protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022856	protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022857	transmembrane transporter activity	molecular_function	Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0022858	alanine transmembrane transporter activity	molecular_function	Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.
GO:0022859	dephosphorylation-gated channel activity	molecular_function	Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.
GO:0022869	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022870	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022871	protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022872	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022873	protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022874	protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022875	protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022876	protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022877	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022878	protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022879	protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022880	protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022881	protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022882	protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0022883	zinc efflux transmembrane transporter activity	molecular_function	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.
GO:0022884	macromolecule transmembrane transporter activity	molecular_function	Enables the transfer of a macromolecule from one side of a membrane to the other.
GO:0022885	bacteriocin transmembrane transporter activity	molecular_function	Enables the transfer of a bacteriocin from one side of a membrane to the other.
GO:0022886	channel-forming ionophore activity	molecular_function	Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.
GO:0022889	serine transmembrane transporter activity	molecular_function	Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.
GO:0022890	inorganic cation transmembrane transporter activity	molecular_function	Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
GO:0022893	low-affinity tryptophan transmembrane transporter activity	molecular_function	Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0022894	Intermediate conductance calcium-activated potassium channel activity	molecular_function	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
GO:0022897	proton-dependent peptide secondary active transmembrane transporter activity	molecular_function	Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.
GO:0022898	regulation of transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
GO:0022900	electron transport chain	biological_process	A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.
GO:0022904	respiratory electron transport chain	biological_process	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
GO:0023002	nuclear migration to embryo sac poles	biological_process	Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.
GO:0023003	nuclear migration to the embryo sac center	biological_process	Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.
GO:0023019	signal transduction involved in regulation of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
GO:0023021	termination of signal transduction	biological_process	The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.
GO:0023022	termination of T cell signal transduction	biological_process	The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
GO:0023023	MHC protein complex binding	molecular_function	Binding to a major histocompatibility complex.
GO:0023024	MHC class I protein complex binding	molecular_function	Binding to a class I major histocompatibility complex.
GO:0023025	MHC class Ib protein complex binding	molecular_function	Binding to a class Ib major histocompatibility complex.
GO:0023026	MHC class II protein complex binding	molecular_function	Binding to a class II major histocompatibility complex.
GO:0023027	MHC class I protein binding, via antigen binding groove	molecular_function	Binding to a major histocompatibility complex class I molecules via the antigen binding groove.
GO:0023028	MHC class I protein binding, via lateral surface	molecular_function	Binding to a major histocompatibility complex class I molecules via the lateral surface.
GO:0023029	MHC class Ib protein binding	molecular_function	Binding to a major histocompatibility complex class Ib molecules.
GO:0023030	MHC class Ib protein binding, via antigen binding groove	molecular_function	Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.
GO:0023031	MHC class Ib protein binding, via lateral surface	molecular_function	Binding to a major histocompatibility complex class Ib molecules via the lateral surface.
GO:0023035	CD40 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0023041	neuronal signal transduction	biological_process	The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.
GO:0023051	regulation of signaling	biological_process	Any process that modulates the frequency, rate or extent of a signaling process.
GO:0023052	signaling	biological_process	The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0023056	positive regulation of signaling	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
GO:0023057	negative regulation of signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
GO:0023058	adaptation of signaling pathway	biological_process	The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
GO:0023059	positive adaptation of signaling pathway	biological_process	The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
GO:0023061	signal release	biological_process	The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
GO:0030001	metal ion transport	biological_process	The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0030002	intracellular monoatomic anion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom.
GO:0030003	intracellular monoatomic cation homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.
GO:0030007	intracellular potassium ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell.
GO:0030008	TRAPP complex	cellular_component	A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.
GO:0030010	establishment of cell polarity	biological_process	The specification and formation of anisotropic intracellular organization or cell growth patterns.
GO:0030011	maintenance of cell polarity	biological_process	The maintenance of established anisotropic intracellular organization or cell growth patterns.
GO:0030014	CCR4-NOT complex	cellular_component	The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.
GO:0030015	CCR4-NOT core complex	cellular_component	The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.
GO:0030016	myofibril	cellular_component	The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
GO:0030017	sarcomere	cellular_component	The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
GO:0030018	Z disc	cellular_component	Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
GO:0030020	extracellular matrix structural constituent conferring tensile strength	molecular_function	A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.
GO:0030021	extracellular matrix structural constituent conferring compression resistance	molecular_function	A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.
GO:0030023	extracellular matrix constituent conferring elasticity	molecular_function	A component of the extracellular matrix that enables the matrix to recoil after transient stretching.
GO:0030026	intracellular manganese ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of manganese ions within a cell.
GO:0030027	lamellipodium	cellular_component	A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
GO:0030029	actin filament-based process	biological_process	Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
GO:0030030	cell projection organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0030031	cell projection assembly	biological_process	Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0030032	lamellipodium assembly	biological_process	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
GO:0030033	microvillus assembly	biological_process	Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
GO:0030034	microvillar actin bundle assembly	biological_process	Assembly of the parallel bundle of actin filaments at the core of a microvillus.
GO:0030035	microspike assembly	biological_process	Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.
GO:0030036	actin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
GO:0030038	contractile actin filament bundle assembly	biological_process	Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
GO:0030041	actin filament polymerization	biological_process	Assembly of actin filaments by the addition of actin monomers to a filament.
GO:0030042	actin filament depolymerization	biological_process	Disassembly of actin filaments by the removal of actin monomers from a filament.
GO:0030043	actin filament fragmentation	biological_process	The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.
GO:0030046	parallel actin filament bundle assembly	biological_process	Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.
GO:0030047	actin modification	biological_process	Covalent modification of an actin molecule.
GO:0030048	actin filament-based movement	biological_process	Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
GO:0030049	muscle filament sliding	biological_process	The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
GO:0030050	vesicle transport along actin filament	biological_process	Movement of a vesicle along an actin filament, mediated by motor proteins.
GO:0030054	cell junction	cellular_component	A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
GO:0030055	cell-substrate junction	cellular_component	A cell junction that forms a connection between a cell and the extracellular matrix.
GO:0030056	hemidesmosome	cellular_component	A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.
GO:0030057	desmosome	cellular_component	A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
GO:0030058	amine dehydrogenase activity	molecular_function	Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.
GO:0030059	aralkylamine dehydrogenase (azurin) activity	molecular_function	Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].
GO:0030060	L-malate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
GO:0030061	mitochondrial crista	cellular_component	Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.
GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	cellular_component	Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.
GO:0030070	insulin processing	biological_process	The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.
GO:0030071	regulation of mitotic metaphase/anaphase transition	biological_process	Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
GO:0030072	peptide hormone secretion	biological_process	The regulated release of a peptide hormone from a cell.
GO:0030073	insulin secretion	biological_process	The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
GO:0030075	bacterial thylakoid	cellular_component	A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.
GO:0030076	light-harvesting complex	cellular_component	A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.
GO:0030077	plasma membrane light-harvesting complex	cellular_component	A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.
GO:0030078	light-harvesting complex, core complex	cellular_component	Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria.
GO:0030079	light-harvesting complex, peripheral complex	cellular_component	Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.
GO:0030080	B875 antenna complex	cellular_component	Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.
GO:0030081	B800-820 antenna complex	cellular_component	Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.
GO:0030082	B800-850 antenna complex	cellular_component	Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.
GO:0030083	PSI associated light-harvesting complex I, LHCIa subcomplex	cellular_component	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.
GO:0030084	PSI associated light-harvesting complex I, LHCIb subcomplex	cellular_component	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.
GO:0030085	PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex	cellular_component	A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.
GO:0030089	phycobilisome	cellular_component	Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.
GO:0030091	protein repair	biological_process	The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.
GO:0030093	chloroplast photosystem I	cellular_component	Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.
GO:0030094	plasma membrane-derived photosystem I	cellular_component	A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.
GO:0030095	chloroplast photosystem II	cellular_component	An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.
GO:0030096	plasma membrane-derived thylakoid photosystem II	cellular_component	A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.
GO:0030097	hemopoiesis	biological_process	The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
GO:0030098	lymphocyte differentiation	biological_process	The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0030099	myeloid cell differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
GO:0030100	regulation of endocytosis	biological_process	Any process that modulates the frequency, rate or extent of endocytosis.
GO:0030101	natural killer cell activation	biological_process	The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0030103	vasopressin secretion	biological_process	The regulated release of vasopressin from secretory granules into the blood.
GO:0030107	HLA-A specific inhibitory MHC class I receptor activity	molecular_function	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
GO:0030108	HLA-A specific activating MHC class I receptor activity	molecular_function	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.
GO:0030109	HLA-B specific inhibitory MHC class I receptor activity	molecular_function	Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.
GO:0030110	HLA-C specific inhibitory MHC class I receptor activity	molecular_function	Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.
GO:0030111	regulation of Wnt signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
GO:0030112	glycocalyx	cellular_component	A carbohydrate rich layer at the outermost periphery of a cell.
GO:0030114	slime layer	cellular_component	A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.
GO:0030115	S-layer	cellular_component	A crystalline protein layer surrounding some bacteria.
GO:0030116	glial cell-derived neurotrophic factor receptor binding	molecular_function	A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.
GO:0030117	membrane coat	cellular_component	Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.
GO:0030118	clathrin coat	cellular_component	A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.
GO:0030119	AP-type membrane coat adaptor complex	cellular_component	Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
GO:0030120	vesicle coat	cellular_component	A membrane coat found on a coated vesicle.
GO:0030121	AP-1 adaptor complex	cellular_component	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
GO:0030122	AP-2 adaptor complex	cellular_component	A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
GO:0030123	AP-3 adaptor complex	cellular_component	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
GO:0030124	AP-4 adaptor complex	cellular_component	An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
GO:0030125	clathrin vesicle coat	cellular_component	A clathrin coat found on a vesicle.
GO:0030126	COPI vesicle coat	cellular_component	One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.
GO:0030127	COPII vesicle coat	cellular_component	One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
GO:0030128	clathrin coat of endocytic vesicle	cellular_component	A clathrin coat found on an endocytic vesicle.
GO:0030129	clathrin coat of synaptic vesicle	cellular_component	A clathrin coat found on a synaptic vesicle.
GO:0030130	clathrin coat of trans-Golgi network vesicle	cellular_component	A clathrin coat found on a vesicle of the trans-Golgi network.
GO:0030131	clathrin adaptor complex	cellular_component	A membrane coat adaptor complex that links clathrin to a membrane.
GO:0030132	clathrin coat of coated pit	cellular_component	The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
GO:0030133	transport vesicle	cellular_component	Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
GO:0030134	COPII-coated ER to Golgi transport vesicle	cellular_component	A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
GO:0030135	coated vesicle	cellular_component	Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
GO:0030136	clathrin-coated vesicle	cellular_component	A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
GO:0030137	COPI-coated vesicle	cellular_component	A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.
GO:0030139	endocytic vesicle	cellular_component	A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
GO:0030140	trans-Golgi network transport vesicle	cellular_component	A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
GO:0030141	secretory granule	cellular_component	A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
GO:0030142	COPI-coated Golgi to ER transport vesicle	cellular_component	A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.
GO:0030143	COPI-coated inter-Golgi transport vesicle	cellular_component	A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).
GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.
GO:0030145	manganese ion binding	molecular_function	Binding to a manganese ion (Mn).
GO:0030148	sphingolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0030149	sphingolipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0030150	protein import into mitochondrial matrix	biological_process	The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
GO:0030151	molybdenum ion binding	molecular_function	Binding to a molybdenum ion (Mo).
GO:0030152	bacteriocin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
GO:0030153	bacteriocin immunity	biological_process	A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
GO:0030154	cell differentiation	biological_process	The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0030155	regulation of cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
GO:0030156	benzodiazepine receptor binding	molecular_function	Binding to a peripheral benzodiazepine receptor (PBR).
GO:0030157	pancreatic juice secretion	biological_process	The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.
GO:0030158	protein xylosyltransferase activity	molecular_function	Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.
GO:0030159	signaling receptor complex adaptor activity	molecular_function	The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.
GO:0030160	synaptic receptor adaptor activity	molecular_function	The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule.
GO:0030162	regulation of proteolysis	biological_process	Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GO:0030163	protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0030164	protein denaturation	biological_process	Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.
GO:0030165	PDZ domain binding	molecular_function	Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.
GO:0030166	proteoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:0030167	proteoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:0030168	platelet activation	biological_process	A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
GO:0030169	low-density lipoprotein particle binding	molecular_function	Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.
GO:0030170	pyridoxal phosphate binding	molecular_function	Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
GO:0030171	voltage-gated proton channel activity	molecular_function	Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0030172	troponin C binding	molecular_function	Binding to troponin C, the calcium-binding subunit of the troponin complex.
GO:0030174	regulation of DNA-templated DNA replication initiation	biological_process	Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
GO:0030175	filopodium	cellular_component	Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
GO:0030177	positive regulation of Wnt signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
GO:0030178	negative regulation of Wnt signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
GO:0030182	neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron.
GO:0030183	B cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
GO:0030184	nitric oxide transmembrane transporter activity	molecular_function	Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.
GO:0030185	nitric oxide transport	biological_process	The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0030186	melatonin metabolic process	biological_process	The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).
GO:0030187	melatonin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
GO:0030193	regulation of blood coagulation	biological_process	Any process that modulates the frequency, rate or extent of blood coagulation.
GO:0030194	positive regulation of blood coagulation	biological_process	Any process that activates or increases the frequency, rate or extent of blood coagulation.
GO:0030195	negative regulation of blood coagulation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
GO:0030196	cyanide hydratase activity	molecular_function	Catalysis of the reaction: formamide = H2O + hydrogen cyanide.
GO:0030197	extracellular matrix constituent, lubricant activity	molecular_function	Functions as a lubricant for an extracellular matrix, such as a mucous membrane.
GO:0030198	extracellular matrix organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
GO:0030199	collagen fibril organization	biological_process	Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
GO:0030200	heparan sulfate proteoglycan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
GO:0030201	heparan sulfate proteoglycan metabolic process	biological_process	The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
GO:0030202	heparin metabolic process	biological_process	The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030203	glycosaminoglycan metabolic process	biological_process	The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
GO:0030204	chondroitin sulfate metabolic process	biological_process	The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.
GO:0030205	dermatan sulfate metabolic process	biological_process	The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.
GO:0030206	chondroitin sulfate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
GO:0030207	chondroitin sulfate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
GO:0030208	dermatan sulfate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
GO:0030209	dermatan sulfate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
GO:0030210	heparin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030211	heparin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030212	hyaluronan metabolic process	biological_process	The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
GO:0030213	hyaluronan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
GO:0030214	hyaluronan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
GO:0030215	semaphorin receptor binding	molecular_function	Binding to a semaphorin receptor.
GO:0030216	keratinocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.
GO:0030217	T cell differentiation	biological_process	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
GO:0030218	erythrocyte differentiation	biological_process	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
GO:0030219	megakaryocyte differentiation	biological_process	The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
GO:0030220	platelet formation	biological_process	The process in which platelets bud from long processes extended by megakaryocytes.
GO:0030221	basophil differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
GO:0030222	eosinophil differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
GO:0030223	neutrophil differentiation	biological_process	The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
GO:0030224	monocyte differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
GO:0030225	macrophage differentiation	biological_process	The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.
GO:0030226	apolipoprotein receptor activity	molecular_function	Combining with an apolipoprotein to initiate a change in cell activity.
GO:0030228	lipoprotein particle receptor activity	molecular_function	Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
GO:0030229	very-low-density lipoprotein particle receptor activity	molecular_function	Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.
GO:0030232	insulin control element activator complex	cellular_component	Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.
GO:0030233	deoxynucleotide transmembrane transporter activity	molecular_function	Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.
GO:0030234	enzyme regulator activity	molecular_function	Binds to and modulates the activity of an enzyme.
GO:0030235	nitric-oxide synthase regulator activity	molecular_function	Binds to and modulates the activity of nitric oxide synthase.
GO:0030237	female sex determination	biological_process	The specification of female sex of an individual organism.
GO:0030238	male sex determination	biological_process	The specification of male sex of an individual organism.
GO:0030239	myofibril assembly	biological_process	Formation of myofibrils, the repeating units of striated muscle.
GO:0030240	skeletal muscle thin filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.
GO:0030241	skeletal muscle myosin thick filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.
GO:0030242	autophagy of peroxisome	biological_process	The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.
GO:0030243	cellulose metabolic process	biological_process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
GO:0030244	cellulose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
GO:0030245	cellulose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
GO:0030246	carbohydrate binding	molecular_function	Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:0030247	polysaccharide binding	molecular_function	Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
GO:0030248	cellulose binding	molecular_function	Binding to cellulose.
GO:0030249	guanylate cyclase regulator activity	molecular_function	Modulates the activity of guanylate cyclase.
GO:0030250	guanylate cyclase activator activity	molecular_function	Binds to and increases the activity of guanylate cyclase.
GO:0030251	guanylate cyclase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of guanylate cyclase.
GO:0030252	growth hormone secretion	biological_process	The regulated release of growth hormone from secretory granules into the blood.
GO:0030253	protein secretion by the type I secretion system	biological_process	The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
GO:0030254	protein secretion by the type III secretion system	biological_process	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
GO:0030255	protein secretion by the type IV secretion system	biological_process	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.
GO:0030256	type I protein secretion system complex	cellular_component	A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.
GO:0030257	type III protein secretion system complex	cellular_component	A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.
GO:0030258	lipid modification	biological_process	The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.
GO:0030259	lipid glycosylation	biological_process	Covalent attachment of a glycosyl residue to a lipid molecule.
GO:0030261	chromosome condensation	biological_process	The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
GO:0030262	apoptotic nuclear changes	biological_process	Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
GO:0030263	apoptotic chromosome condensation	biological_process	The compaction of chromatin during apoptosis.
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	biological_process	The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.
GO:0030265	phospholipase C-activating rhodopsin mediated signaling pathway	biological_process	A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by a rhodopsin molecule being activated by a photon, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0030266	quinate 3-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
GO:0030267	glyoxylate reductase (NADP+) activity	molecular_function	Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.
GO:0030268	methylenetetrahydromethanopterin dehydrogenase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H+ = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.
GO:0030269	tetrahydromethanopterin S-methyltransferase activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.
GO:0030270	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity	molecular_function	Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H+ = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.
GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity	molecular_function	Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H+ + phosphate.
GO:0030273	melanin-concentrating hormone receptor activity	molecular_function	Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.
GO:0030274	LIM domain binding	molecular_function	Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
GO:0030275	LRR domain binding	molecular_function	Binding to a LRR domain (leucine rich repeats) of a protein.
GO:0030276	clathrin binding	molecular_function	Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
GO:0030277	maintenance of gastrointestinal epithelium	biological_process	Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.
GO:0030278	regulation of ossification	biological_process	Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
GO:0030279	negative regulation of ossification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
GO:0030280	structural constituent of skin epidermis	molecular_function	The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.
GO:0030281	structural constituent of cutaneous appendage	molecular_function	The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.
GO:0030282	bone mineralization	biological_process	The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
GO:0030283	testosterone dehydrogenase [NAD(P)] activity	molecular_function	Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.
GO:0030284	nuclear estrogen receptor activity	molecular_function	Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
GO:0030286	dynein complex	cellular_component	Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
GO:0030287	cell wall-bounded periplasmic space	cellular_component	The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.
GO:0030288	outer membrane-bounded periplasmic space	cellular_component	The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
GO:0030289	protein phosphatase 4 complex	cellular_component	A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
GO:0030290	sphingolipid activator protein activity	molecular_function	Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.
GO:0030291	protein serine/threonine kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase.
GO:0030292	protein tyrosine kinase inhibitor activity	molecular_function	Stops, prevents or reduces the activity of a protein tyrosine kinase.
GO:0030293	transmembrane receptor protein tyrosine kinase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.
GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity	molecular_function	Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.
GO:0030295	protein kinase activator activity	molecular_function	Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
GO:0030296	protein tyrosine kinase activator activity	molecular_function	Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	molecular_function	Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.
GO:0030298	receptor signaling protein tyrosine kinase activator activity	molecular_function	Binds to and increases the activity of a receptor signaling protein tyrosine kinase.
GO:0030299	intestinal cholesterol absorption	biological_process	Uptake of cholesterol into the blood by absorption from the small intestine.
GO:0030300	regulation of intestinal cholesterol absorption	biological_process	Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.
GO:0030301	cholesterol transport	biological_process	The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0030302	deoxynucleotide transport	biological_process	The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.
GO:0030305	heparanase activity	molecular_function	Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.
GO:0030307	positive regulation of cell growth	biological_process	Any process that activates or increases the frequency, rate, extent or direction of cell growth.
GO:0030308	negative regulation of cell growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
GO:0030309	poly-N-acetyllactosamine metabolic process	biological_process	The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
GO:0030310	poly-N-acetyllactosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
GO:0030311	poly-N-acetyllactosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
GO:0030312	external encapsulating structure	cellular_component	A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.
GO:0030313	cell envelope	cellular_component	An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.
GO:0030314	junctional membrane complex	cellular_component	Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).
GO:0030315	T-tubule	cellular_component	Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
GO:0030316	osteoclast differentiation	biological_process	The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
GO:0030317	flagellated sperm motility	biological_process	The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.
GO:0030318	melanocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.
GO:0030321	transepithelial chloride transport	biological_process	The directed movement of chloride ions from one side of an epithelium to the other.
GO:0030322	stabilization of membrane potential	biological_process	The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0030323	respiratory tube development	biological_process	The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.
GO:0030324	lung development	biological_process	The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
GO:0030325	adrenal gland development	biological_process	The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
GO:0030326	embryonic limb morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
GO:0030327	prenylated protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prenylated proteins.
GO:0030328	prenylcysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
GO:0030329	prenylcysteine metabolic process	biological_process	The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
GO:0030330	DNA damage response, signal transduction by p53 class mediator	biological_process	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
GO:0030331	nuclear estrogen receptor binding	molecular_function	Binding to a nuclear estrogen receptor.
GO:0030332	cyclin binding	molecular_function	Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
GO:0030334	regulation of cell migration	biological_process	Any process that modulates the frequency, rate or extent of cell migration.
GO:0030335	positive regulation of cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of cell migration.
GO:0030336	negative regulation of cell migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
GO:0030337	DNA polymerase processivity factor activity	molecular_function	An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.
GO:0030338	CMP-N-acetylneuraminate monooxygenase activity	molecular_function	Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.
GO:0030339	fatty-acyl-ethyl-ester synthase activity	molecular_function	Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.
GO:0030340	hyaluronate lyase activity	molecular_function	Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine.
GO:0030341	chondroitin AC lyase activity	molecular_function	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).
GO:0030343	vitamin D3 25-hydroxylase activity	molecular_function	Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O.
GO:0030345	structural constituent of tooth enamel	molecular_function	The action of a molecule that contributes to the structural integrity of tooth enamel.
GO:0030346	protein phosphatase 2B binding	molecular_function	Binding to a protein phosphatase 2B.
GO:0030348	syntaxin-3 binding	molecular_function	Binding to a syntaxin-3 SNAP receptor.
GO:0030350	iron-responsive element binding	molecular_function	Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.
GO:0030351	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.
GO:0030352	inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
GO:0030353	fibroblast growth factor receptor antagonist activity	molecular_function	Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.
GO:0030354	melanin-concentrating hormone activity	molecular_function	The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.
GO:0030366	molybdopterin synthase activity	molecular_function	Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
GO:0030367	interleukin-17 receptor binding	molecular_function	Binding to an interleukin-17 receptor.
GO:0030368	interleukin-17 receptor activity	molecular_function	Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0030369	ICAM-3 receptor activity	molecular_function	Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.
GO:0030370	intercellular adhesion molecule-3 receptor binding	molecular_function	Binding to a receptor for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.
GO:0030371	translation repressor activity	molecular_function	Antagonizes ribosome-mediated translation of mRNA into a polypeptide.
GO:0030372	high molecular weight B cell growth factor receptor binding	molecular_function	Binding to a high molecular weight B cell growth factor receptor.
GO:0030373	high molecular weight B cell growth factor receptor activity	molecular_function	Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.
GO:0030374	nuclear receptor coactivator activity	molecular_function	A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.
GO:0030377	urokinase plasminogen activator receptor activity	molecular_function	Combining with the urokinase plasminogen activator to initiate a change in cell activity.
GO:0030378	serine racemase activity	molecular_function	Catalysis of the synthesis of free D-serine from L-serine.
GO:0030379	neurotensin receptor activity, non-G protein-coupled	molecular_function	Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.
GO:0030380	interleukin-17E receptor binding	molecular_function	Binding to an interleukin-17E receptor.
GO:0030381	chorion-containing eggshell pattern formation	biological_process	The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.
GO:0030382	sperm mitochondrion organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.
GO:0030386	ferredoxin-thioredoxin reductase complex	cellular_component	A protein complex that possesses ferredoxin-thioredoxin reductase activity.
GO:0030388	fructose 1,6-bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
GO:0030389	fructosamine metabolic process	biological_process	The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
GO:0030391	fructosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
GO:0030392	fructosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
GO:0030393	fructoselysine metabolic process	biological_process	The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.
GO:0030394	fructoseglycine metabolic process	biological_process	The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.
GO:0030395	lactose binding	molecular_function	Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.
GO:0030397	membrane disassembly	biological_process	The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.
GO:0030398	peroxisomal membrane disassembly	biological_process	The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation.
GO:0030399	autophagosome membrane disassembly	biological_process	The controlled breakdown of the membranes of autophagosomes.
GO:0030408	glycine formimidoyltransferase activity	molecular_function	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.
GO:0030409	glutamate formimidoyltransferase activity	molecular_function	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.
GO:0030410	nicotianamine synthase activity	molecular_function	Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H+ + nicotianamine.
GO:0030411	scytalone dehydratase activity	molecular_function	Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H2O.
GO:0030412	formimidoyltetrahydrofolate cyclodeaminase activity	molecular_function	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H+ = 5,10-methenyltetrahydrofolate + NH4.
GO:0030413	competence pheromone activity	molecular_function	A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.
GO:0030414	peptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
GO:0030416	methylamine metabolic process	biological_process	The chemical reactions and pathways involving methylamine (CH3NH2).
GO:0030417	nicotianamine metabolic process	biological_process	The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
GO:0030418	nicotianamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
GO:0030419	nicotianamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
GO:0030420	establishment of competence for transformation	biological_process	The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.
GO:0030421	defecation	biological_process	The expulsion of feces from the rectum.
GO:0030422	siRNA processing	biological_process	A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase.
GO:0030424	axon	cellular_component	The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
GO:0030425	dendrite	cellular_component	A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
GO:0030426	growth cone	cellular_component	The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
GO:0030427	site of polarized growth	cellular_component	Any part of a cell where non-isotropic growth takes place.
GO:0030428	cell septum	cellular_component	A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
GO:0030429	kynureninase activity	molecular_function	Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.
GO:0030430	host cell cytoplasm	cellular_component	The cytoplasm of a host cell.
GO:0030431	sleep	biological_process	Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
GO:0030432	peristalsis	biological_process	A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.
GO:0030433	ubiquitin-dependent ERAD pathway	biological_process	The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
GO:0030435	sporulation resulting in formation of a cellular spore	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
GO:0030436	asexual sporulation	biological_process	The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.
GO:0030437	ascospore formation	biological_process	The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
GO:0030445	yeast-form cell wall	cellular_component	The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
GO:0030446	hyphal cell wall	cellular_component	The cell wall surrounding a fungal hypha.
GO:0030447	filamentous growth	biological_process	The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
GO:0030448	hyphal growth	biological_process	Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
GO:0030449	regulation of complement activation	biological_process	Any process that modulates the frequency, rate or extent of complement activation.
GO:0030450	regulation of complement activation, classical pathway	biological_process	Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.
GO:0030451	regulation of complement activation, alternative pathway	biological_process	Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.
GO:0030466	silent mating-type cassette heterochromatin formation	biological_process	Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
GO:0030473	nuclear migration along microtubule	biological_process	The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.
GO:0030474	spindle pole body duplication	biological_process	Construction of a new spindle pole body.
GO:0030476	ascospore wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.
GO:0030478	actin cap	cellular_component	Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.
GO:0030479	actin cortical patch	cellular_component	An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
GO:0030485	smooth muscle contractile fiber	cellular_component	The contractile fiber of smooth muscle cells.
GO:0030486	smooth muscle dense body	cellular_component	Electron-dense region associated with a smooth muscle contractile fiber.
GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
GO:0030488	tRNA methylation	biological_process	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
GO:0030490	maturation of SSU-rRNA	biological_process	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
GO:0030491	heteroduplex formation	biological_process	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.
GO:0030492	hemoglobin binding	molecular_function	Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
GO:0030493	bacteriochlorophyll metabolic process	biological_process	The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
GO:0030494	bacteriochlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
GO:0030495	bacteriochlorophyll catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
GO:0030496	midbody	cellular_component	A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
GO:0030497	fatty acid elongation	biological_process	The elongation of a fatty acid chain by the sequential addition of two-carbon units.
GO:0030500	regulation of bone mineralization	biological_process	Any process that modulates the frequency, rate or extent of bone mineralization.
GO:0030501	positive regulation of bone mineralization	biological_process	Any process that activates or increases the frequency, rate or extent of bone mineralization.
GO:0030502	negative regulation of bone mineralization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.
GO:0030504	inorganic diphosphate transmembrane transporter activity	molecular_function	Enables the transfer of inorganic diphosphate across a membrane.
GO:0030505	inorganic diphosphate transport	biological_process	The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0030506	ankyrin binding	molecular_function	Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
GO:0030507	spectrin binding	molecular_function	Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
GO:0030509	BMP signaling pathway	biological_process	The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0030510	regulation of BMP signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
GO:0030513	positive regulation of BMP signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
GO:0030514	negative regulation of BMP signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
GO:0030515	snoRNA binding	molecular_function	Binding to a small nucleolar RNA.
GO:0030516	regulation of axon extension	biological_process	Any process that modulates the rate, direction or extent of axon extension.
GO:0030517	negative regulation of axon extension	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
GO:0030518	intracellular steroid hormone receptor signaling pathway	biological_process	The series of molecular signals initiated by a steroid binding to an intracellular steroid hormone receptor.
GO:0030519	snoRNP binding	molecular_function	Binding to a small nucleolar ribonucleoprotein particle.
GO:0030520	intracellular estrogen receptor signaling pathway	biological_process	The series of molecular signals initiated by estrogen binding to an intracellular receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0030521	androgen receptor signaling pathway	biological_process	The series of molecular signals initiated by androgen binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0030522	intracellular receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a receptor located within a cell.
GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex	cellular_component	The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.
GO:0030527	structural constituent of chromatin	molecular_function	The action of a molecule that contributes to the structural integrity of chromatin.
GO:0030532	small nuclear ribonucleoprotein complex	cellular_component	A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs.
GO:0030533	triplet codon-amino acid adaptor activity	molecular_function	The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
GO:0030534	adult behavior	biological_process	Behavior in a fully developed and mature organism.
GO:0030536	larval feeding behavior	biological_process	Feeding behavior in a larval (immature) organism.
GO:0030537	larval behavior	biological_process	Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.
GO:0030538	embryonic genitalia morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.
GO:0030539	male genitalia development	biological_process	The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.
GO:0030540	female genitalia development	biological_process	The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.
GO:0030541	plasmid partitioning	biological_process	Any process in which plasmids are segregated or distributed into daughter cells upon cell division.
GO:0030543	2-micrometer plasmid partitioning	biological_process	The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.
GO:0030544	Hsp70 protein binding	molecular_function	Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.
GO:0030545	signaling receptor regulator activity	molecular_function	Binds to and modulates the activity of a receptor.
GO:0030546	signaling receptor activator activity	molecular_function	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.
GO:0030547	signaling receptor inhibitor activity	molecular_function	Binds to and modulates the activity of a signaling receptor.
GO:0030548	acetylcholine receptor regulator activity	molecular_function	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
GO:0030549	acetylcholine receptor activator activity	molecular_function	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.
GO:0030550	acetylcholine receptor inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of an acetylcholine receptor.
GO:0030551	cyclic nucleotide binding	molecular_function	Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
GO:0030552	cAMP binding	molecular_function	Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
GO:0030553	cGMP binding	molecular_function	Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
GO:0030554	adenyl nucleotide binding	molecular_function	Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.
GO:0030555	RNA modification guide activity	molecular_function	Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
GO:0030556	rRNA modification guide activity	molecular_function	Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.
GO:0030557	tRNA modification guide activity	molecular_function	Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.
GO:0030558	RNA pseudouridylation guide activity	molecular_function	Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.
GO:0030559	rRNA pseudouridylation guide activity	molecular_function	Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.
GO:0030560	tRNA pseudouridylation guide activity	molecular_function	Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.
GO:0030561	RNA 2'-O-ribose methylation guide activity	molecular_function	Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.
GO:0030562	rRNA 2'-O-ribose methylation guide activity	molecular_function	Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.
GO:0030563	snRNA 2'-O-ribose methylation guide activity	molecular_function	Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.
GO:0030564	tRNA 2'-O-ribose methylation guide activity	molecular_function	Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.
GO:0030565	snRNA pseudouridylation guide activity	molecular_function	Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.
GO:0030566	snRNA modification guide activity	molecular_function	Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.
GO:0030570	pectate lyase activity	molecular_function	Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.
GO:0030572	phosphatidyltransferase activity	molecular_function	Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.
GO:0030573	bile acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
GO:0030574	collagen catabolic process	biological_process	The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
GO:0030575	nuclear body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
GO:0030576	Cajal body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.
GO:0030577	Lands organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.
GO:0030578	PML body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).
GO:0030580	quinone cofactor methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1).
GO:0030581	symbiont intracellular protein transport in host	biological_process	The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0030582	reproductive fruiting body development	biological_process	The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.
GO:0030583	myxococcal fruiting body development	biological_process	The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.
GO:0030584	sporocarp development	biological_process	The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.
GO:0030585	phosphoenolpyruvate carboxykinase (diphosphate) activity	molecular_function	Catalysis of the reaction: diphosphate + oxaloacetate = CO2 + phosphate + phosphoenolpyruvate.
GO:0030586	[methionine synthase] reductase activity	molecular_function	Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.
GO:0030587	sorocarp development	biological_process	The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
GO:0030588	pseudocleavage	biological_process	Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.
GO:0030589	pseudocleavage involved in syncytial blastoderm formation	biological_process	Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
GO:0030590	first cell cycle pseudocleavage	biological_process	A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.
GO:0030591	2'-deoxyguanosine DNA ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.
GO:0030592	DNA ADP-ribosylation	biological_process	The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.
GO:0030593	neutrophil chemotaxis	biological_process	The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
GO:0030594	neurotransmitter receptor activity	molecular_function	Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.
GO:0030595	leukocyte chemotaxis	biological_process	The movement of a leukocyte in response to an external stimulus.
GO:0030596	alpha-L-rhamnosidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.
GO:0030597	RNA glycosylase activity	molecular_function	Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule.
GO:0030598	rRNA N-glycosylase activity	molecular_function	Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.
GO:0030599	pectinesterase activity	molecular_function	Catalysis of the reaction: pectin + n H2O = n methanol + pectate.
GO:0030600	feruloyl esterase activity	molecular_function	Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.
GO:0030603	oxaloacetase activity	molecular_function	Catalysis of the reaction: H2O + oxaloacetate = acetate + H+ + oxalate.
GO:0030604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	molecular_function	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + H+ + NADPH.
GO:0030611	arsenate reductase activity	molecular_function	Catalysis of the interconversion of arsenate and arsenite.
GO:0030612	arsenate reductase (thioredoxin) activity	molecular_function	Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin.
GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0030614	oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0030619	U1 snRNA binding	molecular_function	Binding to a U1 small nuclear RNA (U1 snRNA).
GO:0030620	U2 snRNA binding	molecular_function	Binding to a U2 small nuclear RNA (U2 snRNA).
GO:0030621	U4 snRNA binding	molecular_function	Binding to a U4 small nuclear RNA (U4 snRNA).
GO:0030622	U4atac snRNA binding	molecular_function	Binding to a U4atac small nuclear RNA (U4atac snRNA).
GO:0030623	U5 snRNA binding	molecular_function	Binding to a U5 small nuclear RNA (U5 snRNA).
GO:0030624	U6atac snRNA binding	molecular_function	Binding to a U6atac small nuclear RNA (U6atac snRNA).
GO:0030625	U11 snRNA binding	molecular_function	Binding to a U11 small nuclear RNA (U11 snRNA).
GO:0030626	U12 snRNA binding	molecular_function	Binding to a U12 small nuclear RNA (U12 snRNA).
GO:0030627	pre-mRNA 5'-splice site binding	molecular_function	Binding to a pre-mRNA 5' splice site sequence.
GO:0030628	pre-mRNA 3'-splice site binding	molecular_function	Binding to a pre-mRNA 3' splice site sequence.
GO:0030629	U6 snRNA 3'-end binding	molecular_function	Binding to a U6 small nuclear RNA (U6 snRNA) at the 3' end.
GO:0030631	pyrrolysine incorporation	biological_process	The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.
GO:0030632	D-alanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.
GO:0030634	carbon fixation by acetyl-CoA pathway	biological_process	A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).
GO:0030638	polyketide metabolic process	biological_process	The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
GO:0030639	polyketide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
GO:0030640	polyketide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
GO:0030641	regulation of cellular pH	biological_process	Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.
GO:0030642	intracellular sulfate ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell.
GO:0030643	intracellular phosphate ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell.
GO:0030644	intracellular chloride ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of chloride ions within a cell.
GO:0030645	glucose catabolic process to butyrate	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.
GO:0030647	aminoglycoside antibiotic metabolic process	biological_process	The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
GO:0030648	aminoglycoside antibiotic biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
GO:0030649	aminoglycoside antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
GO:0030650	peptide antibiotic metabolic process	biological_process	The chemical reactions and pathways involving peptides with antibiotic activity.
GO:0030651	peptide antibiotic biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.
GO:0030652	peptide antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.
GO:0030653	beta-lactam antibiotic metabolic process	biological_process	The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
GO:0030654	beta-lactam antibiotic biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
GO:0030655	beta-lactam antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
GO:0030656	regulation of vitamin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0030658	transport vesicle membrane	cellular_component	The lipid bilayer surrounding a transport vesicle.
GO:0030659	cytoplasmic vesicle membrane	cellular_component	The lipid bilayer surrounding a cytoplasmic vesicle.
GO:0030660	Golgi-associated vesicle membrane	cellular_component	The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
GO:0030661	chitosome membrane	cellular_component	The lipid bilayer surrounding a chitosome.
GO:0030662	coated vesicle membrane	cellular_component	The lipid bilayer surrounding a coated vesicle.
GO:0030663	COPI-coated vesicle membrane	cellular_component	The lipid bilayer surrounding a COPI-coated vesicle.
GO:0030665	clathrin-coated vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-coated vesicle.
GO:0030666	endocytic vesicle membrane	cellular_component	The lipid bilayer surrounding an endocytic vesicle.
GO:0030667	secretory granule membrane	cellular_component	The lipid bilayer surrounding a secretory granule.
GO:0030668	merozoite dense granule membrane	cellular_component	The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.
GO:0030669	clathrin-coated endocytic vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-coated endocytic vesicle.
GO:0030670	phagocytic vesicle membrane	cellular_component	The lipid bilayer surrounding a phagocytic vesicle.
GO:0030671	clathrin-coated phagocytic vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.
GO:0030672	synaptic vesicle membrane	cellular_component	The lipid bilayer surrounding a synaptic vesicle.
GO:0030673	axolemma	cellular_component	The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
GO:0030674	protein-macromolecule adaptor activity	molecular_function	The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
GO:0030677	ribonuclease P complex	cellular_component	A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.
GO:0030678	mitochondrial ribonuclease P complex	cellular_component	A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.
GO:0030679	cyanelle ribonuclease P complex	cellular_component	A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
GO:0030680	dimeric ribonuclease P complex	cellular_component	A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.
GO:0030681	multimeric ribonuclease P complex	cellular_component	A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
GO:0030682	mitigation of host defenses by symbiont	biological_process	A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0030684	preribosome	cellular_component	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.
GO:0030685	nucleolar preribosome	cellular_component	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.
GO:0030686	90S preribosome	cellular_component	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
GO:0030687	preribosome, large subunit precursor	cellular_component	A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.
GO:0030688	preribosome, small subunit precursor	cellular_component	A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
GO:0030689	Noc complex	cellular_component	Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.
GO:0030690	Noc1p-Noc2p complex	cellular_component	A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.
GO:0030691	Noc2p-Noc3p complex	cellular_component	A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.
GO:0030692	Noc4p-Nop14p complex	cellular_component	A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.
GO:0030694	bacterial-type flagellum basal body, rod	cellular_component	The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.
GO:0030695	GTPase regulator activity	molecular_function	Binds to and modulates the activity of a GTPase.
GO:0030696	tRNA (m5U54) methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.
GO:0030697	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.
GO:0030698	5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.
GO:0030699	glycine reductase activity	molecular_function	Catalysis of the reaction: acetyl phosphate + H2O + NH4 + thioredoxin disulfide = glycine + H+ + phosphate + thioredoxin.
GO:0030700	glycine reductase complex	cellular_component	Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.
GO:0030701	NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity	molecular_function	Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].
GO:0030703	eggshell formation	biological_process	Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.
GO:0030704	vitelline membrane formation	biological_process	Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.
GO:0030705	cytoskeleton-dependent intracellular transport	biological_process	The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
GO:0030706	germarium-derived oocyte differentiation	biological_process	The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.
GO:0030707	follicle cell of egg chamber development	biological_process	The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
GO:0030708	germarium-derived female germ-line cyst encapsulation	biological_process	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.
GO:0030709	border follicle cell delamination	biological_process	The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.
GO:0030710	regulation of border follicle cell delamination	biological_process	Any process that regulates the frequency, rate or extent of border cell delamination.
GO:0030711	positive regulation of border follicle cell delamination	biological_process	Any process that increases the frequency, rate or extent of border cell delamination.
GO:0030712	negative regulation of border follicle cell delamination	biological_process	Any process that decreases the frequency, rate or extent of border cell delamination.
GO:0030713	follicle cell of egg chamber stalk formation	biological_process	Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.
GO:0030714	anterior/posterior axis specification, follicular epithelium	biological_process	Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.
GO:0030715	oocyte growth in germarium-derived egg chamber	biological_process	The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.
GO:0030716	oocyte fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0030717	oocyte karyosome formation	biological_process	The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0030718	germ-line stem cell population maintenance	biological_process	Any process by which an organism or tissue maintains a population of germ-line stem cells.
GO:0030719	P granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
GO:0030720	oocyte localization involved in germarium-derived egg chamber formation	biological_process	Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.
GO:0030721	spectrosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.
GO:0030723	ovarian fusome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.
GO:0030724	testicular fusome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.
GO:0030725	germline ring canal formation	biological_process	Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.
GO:0030726	male germline ring canal formation	biological_process	Formation of the intercellular bridges that connect the germ-line cells of a male cyst.
GO:0030727	germarium-derived female germ-line cyst formation	biological_process	Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.
GO:0030728	ovulation	biological_process	The release of a mature ovum/oocyte from an ovary.
GO:0030729	acetoacetate-CoA ligase activity	molecular_function	Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.
GO:0030730	sequestering of triglyceride	biological_process	The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
GO:0030731	guanidinoacetate N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H+.
GO:0030732	methionine S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.
GO:0030733	fatty acid O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.
GO:0030734	polysaccharide O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.
GO:0030735	carnosine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H+.
GO:0030736	phenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H+.
GO:0030737	iodophenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H+.
GO:0030738	tyramine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H+.
GO:0030739	O-demethylpuromycin O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.
GO:0030740	inositol 3-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.
GO:0030741	inositol 1-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.
GO:0030742	GTP-dependent protein binding	molecular_function	Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state.
GO:0030743	rRNA (adenosine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.
GO:0030744	luteolin O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H+.
GO:0030745	dimethylhistidine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.
GO:0030746	isoflavone 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.
GO:0030747	indolepyruvate C-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.
GO:0030748	amine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.
GO:0030749	loganate O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.
GO:0030750	putrescine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H+.
GO:0030751	licodione 2'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H+.
GO:0030752	5-hydroxyfuranocoumarin 5-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.
GO:0030753	8-hydroxyfuranocoumarin 8-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.
GO:0030754	apigenin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.
GO:0030755	quercetin 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.
GO:0030756	isoorientin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H+ + isoscoparin.
GO:0030757	3-methylquercitin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.
GO:0030758	3,7-dimethylquercitin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.
GO:0030759	methylquercetagetin 6-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.
GO:0030760	pyridine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.
GO:0030761	8-hydroxyquercitin 8-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H+.
GO:0030762	tetrahydrocolumbamine 2-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H+ + tetrahydropalmatine.
GO:0030763	isobutyraldoxime O-methyltransferase activity	molecular_function	Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H+.
GO:0030766	11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.
GO:0030767	3-hydroxyanthranilate 4-C-methyltransferase activity	molecular_function	Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H+.
GO:0030768	16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H+.
GO:0030769	macrocin O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H+ + tylosin.
GO:0030770	demethylmacrocin O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H+ + macrocin.
GO:0030771	N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity	molecular_function	Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H+.
GO:0030772	tryptophan 2-C-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H+.
GO:0030773	6-hydroxymellein O-methyltransferase activity	molecular_function	Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H+.
GO:0030774	anthranilate N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H+.
GO:0030775	glucuronoxylan 4-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.
GO:0030776	(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.
GO:0030777	(S)-scoulerine 9-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H+.
GO:0030778	columbamine O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H+ + palmatine.
GO:0030779	10-hydroxydihydrosanguinarine 10-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H+.
GO:0030780	12-hydroxydihydrochelirubine 12-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H+.
GO:0030781	6-O-methylnorlaudanosoline 5'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.
GO:0030782	(S)-tetrahydroprotoberberine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine.
GO:0030783	[cytochrome c]-methionine S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.
GO:0030784	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.
GO:0030785	[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.
GO:0030786	(RS)-norcoclaurine 6-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.
GO:0030787	inositol 4-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.
GO:0030788	precorrin-2 C20-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H+ + precorrin-3A.
GO:0030789	precorrin-3B C17-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.
GO:0030790	chlorophenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.
GO:0030791	arsenite methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.
GO:0030792	methylarsonite methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.
GO:0030793	3'-demethylstaurosporine O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H+ + staurosporine.
GO:0030794	(S)-coclaurine-N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.
GO:0030795	methyl jasmonate methylesterase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate.
GO:0030796	cycloartenol 24-C-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H+.
GO:0030797	24-methylenesterol C-methyltransferase activity	molecular_function	Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H+.
GO:0030798	trans-aconitate 2-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.
GO:0030805	regulation of cyclic nucleotide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.
GO:0030808	regulation of nucleotide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GO:0030809	negative regulation of nucleotide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GO:0030810	positive regulation of nucleotide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
GO:0030811	regulation of nucleotide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
GO:0030812	negative regulation of nucleotide catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
GO:0030813	positive regulation of nucleotide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
GO:0030832	regulation of actin filament length	biological_process	Any process that controls the length of actin filaments in a cell.
GO:0030833	regulation of actin filament polymerization	biological_process	Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
GO:0030834	regulation of actin filament depolymerization	biological_process	Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.
GO:0030835	negative regulation of actin filament depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.
GO:0030836	positive regulation of actin filament depolymerization	biological_process	Any process that activates or increases the frequency, rate or extent of actin depolymerization.
GO:0030837	negative regulation of actin filament polymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
GO:0030838	positive regulation of actin filament polymerization	biological_process	Any process that activates or increases the frequency, rate or extent of actin polymerization.
GO:0030839	regulation of intermediate filament polymerization	biological_process	Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.
GO:0030840	negative regulation of intermediate filament polymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization.
GO:0030841	positive regulation of intermediate filament polymerization	biological_process	Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.
GO:0030842	regulation of intermediate filament depolymerization	biological_process	Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.
GO:0030843	negative regulation of intermediate filament depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization.
GO:0030844	positive regulation of intermediate filament depolymerization	biological_process	Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.
GO:0030845	phospholipase C-inhibiting G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).
GO:0030846	termination of RNA polymerase II transcription, poly(A)-coupled	biological_process	An RNA polymerase II transcription termination process in which cleavage and polyadenylylation of the mRNA 3' end are coupled to transcription termination.
GO:0030847	termination of RNA polymerase II transcription, exosome-dependent	biological_process	The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
GO:0030848	threo-3-hydroxyaspartate ammonia-lyase activity	molecular_function	Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH4 + oxaloacetate.
GO:0030849	autosome	cellular_component	Any chromosome other than a sex chromosome.
GO:0030850	prostate gland development	biological_process	The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
GO:0030851	granulocyte differentiation	biological_process	The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
GO:0030852	regulation of granulocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of granulocyte differentiation.
GO:0030853	negative regulation of granulocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.
GO:0030854	positive regulation of granulocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.
GO:0030855	epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
GO:0030856	regulation of epithelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
GO:0030857	negative regulation of epithelial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.
GO:0030858	positive regulation of epithelial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.
GO:0030859	polarized epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.
GO:0030860	regulation of polarized epithelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.
GO:0030861	negative regulation of polarized epithelial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation.
GO:0030862	positive regulation of polarized epithelial cell differentiation	biological_process	Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.
GO:0030863	cortical cytoskeleton	cellular_component	The portion of the cytoskeleton that lies just beneath the plasma membrane.
GO:0030864	cortical actin cytoskeleton	cellular_component	The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
GO:0030865	cortical cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
GO:0030866	cortical actin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
GO:0030867	rough endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the rough endoplasmic reticulum.
GO:0030868	smooth endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the smooth endoplasmic reticulum.
GO:0030869	RENT complex	cellular_component	A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit.
GO:0030870	Mre11 complex	cellular_component	Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.
GO:0030874	nucleolar chromatin	cellular_component	The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.
GO:0030875	rDNA protrusion	cellular_component	Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining.
GO:0030876	interleukin-20 receptor complex	cellular_component	A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.
GO:0030877	beta-catenin destruction complex	cellular_component	A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
GO:0030878	thyroid gland development	biological_process	The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.
GO:0030879	mammary gland development	biological_process	The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
GO:0030880	RNA polymerase complex	cellular_component	Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.
GO:0030881	beta-2-microglobulin binding	molecular_function	Binding to beta-2-microglobulin.
GO:0030882	lipid antigen binding	molecular_function	Binding to a lipid antigen.
GO:0030883	endogenous lipid antigen binding	molecular_function	Binding to an endogenous cellular lipid antigen.
GO:0030884	exogenous lipid antigen binding	molecular_function	Binding to an exogenous lipid antigen (examples include microbial lipids and glycolipids).
GO:0030885	regulation of myeloid dendritic cell activation	biological_process	Any process that modulates the frequency or rate of myeloid dendritic cell activation.
GO:0030886	negative regulation of myeloid dendritic cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.
GO:0030887	positive regulation of myeloid dendritic cell activation	biological_process	Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.
GO:0030888	regulation of B cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of B cell proliferation.
GO:0030889	negative regulation of B cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of B cell proliferation.
GO:0030890	positive regulation of B cell proliferation	biological_process	Any process that activates or increases the rate or extent of B cell proliferation.
GO:0030891	VCB complex	cellular_component	A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
GO:0030892	mitotic cohesin complex	cellular_component	A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.
GO:0030893	meiotic cohesin complex	cellular_component	A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
GO:0030894	replisome	cellular_component	A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
GO:0030895	apolipoprotein B mRNA editing enzyme complex	cellular_component	Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
GO:0030896	checkpoint clamp complex	cellular_component	Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.
GO:0030897	HOPS complex	cellular_component	A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.
GO:0030899	calcium-dependent ATPase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).
GO:0030900	forebrain development	biological_process	The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
GO:0030901	midbrain development	biological_process	The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
GO:0030902	hindbrain development	biological_process	The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
GO:0030903	notochord development	biological_process	The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
GO:0030904	retromer complex	cellular_component	A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
GO:0030905	retromer, tubulation complex	cellular_component	The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.
GO:0030906	retromer, cargo-selective complex	cellular_component	The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
GO:0030907	MBF transcription complex	cellular_component	A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.
GO:0030908	protein splicing	biological_process	The post-translational removal of peptide sequences from within a protein sequence.
GO:0030909	non-intein-mediated protein splicing	biological_process	The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.
GO:0030910	olfactory placode formation	biological_process	The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
GO:0030911	TPR domain binding	molecular_function	Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
GO:0030912	response to deep water	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.
GO:0030913	paranodal junction assembly	biological_process	Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.
GO:0030915	Smc5-Smc6 complex	cellular_component	A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
GO:0030916	otic vesicle formation	biological_process	The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.
GO:0030917	midbrain-hindbrain boundary development	biological_process	The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
GO:0030919	peptidyl-serine O-acetylation	biological_process	The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine.
GO:0030920	peptidyl-serine acetylation	biological_process	The acetylation of peptidyl-serine.
GO:0030921	peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine	biological_process	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.
GO:0030922	peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine	biological_process	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.
GO:0030929	ADPG pyrophosphorylase complex	cellular_component	Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.
GO:0030930	homotetrameric ADPG pyrophosphorylase complex	cellular_component	A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species.
GO:0030931	heterotetrameric ADPG pyrophosphorylase complex	cellular_component	A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus.
GO:0030932	amyloplast ADPG pyrophosphorylase complex	cellular_component	An ADPG pyrophosphorylase complex found in the amyloplast.
GO:0030933	chloroplast ADPG pyrophosphorylase complex	cellular_component	An ADPG pyrophosphorylase complex found in the chloroplast.
GO:0030934	anchoring collagen complex	cellular_component	Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures.
GO:0030935	sheet-forming collagen trimer	cellular_component	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet.
GO:0030936	transmembrane collagen trimer	cellular_component	Any collagen trimer that passes through a lipid bilayer membrane.
GO:0030937	collagen type XVII trimer	cellular_component	A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin.
GO:0030938	collagen type XVIII trimer	cellular_component	A collagen homotrimer of alpha1(XVIII) chains.
GO:0030941	chloroplast targeting sequence binding	molecular_function	Binding to a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.
GO:0030942	endoplasmic reticulum signal peptide binding	molecular_function	Binding to an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.
GO:0030943	mitochondrion targeting sequence binding	molecular_function	Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion.
GO:0030944	DDEL sequence binding	molecular_function	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
GO:0030945	protein tyrosine phosphatase activity, via thiol-phosphate intermediate	molecular_function	The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate.
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	molecular_function	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
GO:0030952	establishment or maintenance of cytoskeleton polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.
GO:0030953	astral microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.
GO:0030954	astral microtubule nucleation	biological_process	The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.
GO:0030955	potassium ion binding	molecular_function	Binding to a potassium ion (K+).
GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	cellular_component	A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.
GO:0030957	Tat protein binding	molecular_function	Binding to Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus.
GO:0030958	RITS complex	cellular_component	A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing.
GO:0030959	peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine	biological_process	The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link.
GO:0030960	peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine	biological_process	The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link.
GO:0030961	peptidyl-arginine hydroxylation	biological_process	The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.
GO:0030962	peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine	biological_process	The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.
GO:0030963	peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine	biological_process	The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine.
GO:0030964	NADH dehydrogenase complex	cellular_component	An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
GO:0030965	plasma membrane electron transport, NADH to quinone	biological_process	The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.
GO:0030968	endoplasmic reticulum unfolded protein response	biological_process	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
GO:0030970	retrograde protein transport, ER to cytosol	biological_process	The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
GO:0030971	receptor tyrosine kinase binding	molecular_function	Binding to a receptor that possesses protein tyrosine kinase activity.
GO:0030973	molybdate ion binding	molecular_function	Binding to a molybdate ion (MoO4 2-).
GO:0030974	thiamine pyrophosphate transmembrane transport	biological_process	The process in which thiamine pyrophosphate is transported across a membrane.
GO:0030975	thiamine binding	molecular_function	Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0030976	thiamine pyrophosphate binding	molecular_function	Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
GO:0030977	taurine binding	molecular_function	Binding to taurine.
GO:0030978	alpha-glucan metabolic process	biological_process	The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
GO:0030979	alpha-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
GO:0030980	alpha-glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alpha-glucans.
GO:0030981	cortical microtubule cytoskeleton	cellular_component	The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.
GO:0030982	adventurous gliding motility	biological_process	A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.
GO:0030983	mismatched DNA binding	molecular_function	Binding to a double-stranded DNA region containing one or more mismatches.
GO:0030984	kininogen binding	molecular_function	Binding to a kininogen, a kinin precursor.
GO:0030985	high molecular weight kininogen binding	molecular_function	Binding to a kininogen of high molecular mass.
GO:0030986	low molecular weight kininogen binding	molecular_function	Binding to a kininogen of low molecular mass.
GO:0030987	high molecular weight kininogen receptor binding	molecular_function	Binding to a high molecular weight kininogen receptor.
GO:0030988	high molecular weight kininogen receptor complex	cellular_component	A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.
GO:0030989	dynein-driven meiotic oscillatory nuclear movement	biological_process	Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.
GO:0030990	intraciliary transport particle	cellular_component	A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
GO:0030991	intraciliary transport particle A	cellular_component	The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
GO:0030992	intraciliary transport particle B	cellular_component	The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
GO:0030993	axonemal heterotrimeric kinesin-II complex	cellular_component	A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.
GO:0030994	primary cell septum disassembly	biological_process	Dissolution of the primary septum during cell separation.
GO:0030995	cell septum edging catabolic process	biological_process	The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.
GO:0030997	regulation of centriole-centriole cohesion	biological_process	Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.
GO:0030998	linear element	cellular_component	A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex.
GO:0030999	linear element assembly	biological_process	The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex.
GO:0031000	response to caffeine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
GO:0031001	response to brefeldin A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.
GO:0031002	actin rod	cellular_component	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions.
GO:0031003	actin tubule	cellular_component	A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.
GO:0031004	potassium ion-transporting ATPase complex	cellular_component	Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.
GO:0031005	filamin binding	molecular_function	Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
GO:0031009	plastid ADPG pyrophosphorylase complex	cellular_component	An ADPG pyrophosphorylase complex found in a plastid.
GO:0031010	ISWI-type complex	cellular_component	Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.
GO:0031011	Ino80 complex	cellular_component	A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.
GO:0031012	extracellular matrix	cellular_component	A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
GO:0031013	troponin I binding	molecular_function	Binding to troponin I, the inhibitory subunit of the troponin complex.
GO:0031014	troponin T binding	molecular_function	Binding to troponin T, the tropomyosin-binding subunit of the troponin complex.
GO:0031016	pancreas development	biological_process	The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.
GO:0031017	exocrine pancreas development	biological_process	The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
GO:0031018	endocrine pancreas development	biological_process	The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
GO:0031019	mitochondrial mRNA editing complex	cellular_component	An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
GO:0031020	plastid mRNA editing complex	cellular_component	An mRNA editing complex found in a plastid.
GO:0031021	interphase microtubule organizing center	cellular_component	A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.
GO:0031022	nuclear migration along microfilament	biological_process	The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.
GO:0031023	microtubule organizing center organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
GO:0031024	interphase microtubule organizing center assembly	biological_process	The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.
GO:0031025	equatorial microtubule organizing center disassembly	biological_process	The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.
GO:0031026	glutamate synthase complex	cellular_component	A complex that possesses glutamate synthase activity.
GO:0031027	glutamate synthase complex (NADH)	cellular_component	A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.
GO:0031028	septation initiation signaling	biological_process	The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.
GO:0031029	regulation of septation initiation signaling	biological_process	Any process that modulates the frequency, rate or extent of septation initiation signaling.
GO:0031030	negative regulation of septation initiation signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.
GO:0031031	positive regulation of septation initiation signaling	biological_process	Any process that activates or increases the frequency, rate or extent of septation initiation signaling.
GO:0031032	actomyosin structure organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.
GO:0031033	myosin filament organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.
GO:0031034	myosin filament assembly	biological_process	The aggregation, arrangement and bonding together of a filament composed of myosin molecules.
GO:0031035	myosin filament disassembly	biological_process	The disassembly of a filament composed of myosin molecules.
GO:0031036	myosin II filament assembly	biological_process	The formation of a bipolar filament composed of myosin II molecules.
GO:0031037	myosin II filament disassembly	biological_process	The disassembly of a bipolar filament composed of myosin II molecules.
GO:0031038	myosin II filament organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
GO:0031039	macronucleus	cellular_component	A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.
GO:0031040	micronucleus	cellular_component	A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.
GO:0031041	O-glycan processing, core 5	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.
GO:0031042	O-glycan processing, core 6	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.
GO:0031043	O-glycan processing, core 7	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.
GO:0031044	O-glycan processing, core 8	biological_process	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.
GO:0031045	dense core granule	cellular_component	Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
GO:0031047	regulatory ncRNA-mediated gene silencing	biological_process	A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
GO:0031048	regulatory ncRNA-mediated heterochromatin formation	biological_process	A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription.
GO:0031049	programmed DNA elimination	biological_process	A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.
GO:0031052	programmed DNA elimination by chromosome breakage	biological_process	Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
GO:0031053	primary miRNA processing	biological_process	A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
GO:0031054	pre-miRNA processing	biological_process	A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
GO:0031055	chromatin remodeling at centromere	biological_process	Dynamic structural changes in centromeric DNA.
GO:0031056	regulation of histone modification	biological_process	Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.
GO:0031060	regulation of histone methylation	biological_process	Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.
GO:0031061	negative regulation of histone methylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
GO:0031062	positive regulation of histone methylation	biological_process	Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones.
GO:0031063	regulation of histone deacetylation	biological_process	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.
GO:0031064	negative regulation of histone deacetylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones.
GO:0031065	positive regulation of histone deacetylation	biological_process	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
GO:0031069	hair follicle morphogenesis	biological_process	The process in which the anatomical structures of the hair follicle are generated and organized.
GO:0031070	intronic snoRNA processing	biological_process	The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.
GO:0031071	cysteine desulfurase activity	molecular_function	Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.
GO:0031072	heat shock protein binding	molecular_function	Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.
GO:0031073	cholesterol 26-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.
GO:0031074	nucleocytoplasmic transport complex	cellular_component	Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.
GO:0031076	embryonic camera-type eye development	biological_process	The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
GO:0031077	post-embryonic camera-type eye development	biological_process	The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.
GO:0031078	histone H3K14 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
GO:0031080	nuclear pore outer ring	cellular_component	A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).
GO:0031082	BLOC complex	cellular_component	Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.
GO:0031083	BLOC-1 complex	cellular_component	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.
GO:0031084	BLOC-2 complex	cellular_component	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.
GO:0031085	BLOC-3 complex	cellular_component	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.
GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	biological_process	A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA	biological_process	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.
GO:0031088	platelet dense granule membrane	cellular_component	The lipid bilayer surrounding the platelet dense granule.
GO:0031089	platelet dense granule lumen	cellular_component	The volume enclosed by the membrane of the platelet dense granule.
GO:0031090	organelle membrane	cellular_component	A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
GO:0031091	platelet alpha granule	cellular_component	A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
GO:0031092	platelet alpha granule membrane	cellular_component	The lipid bilayer surrounding the platelet alpha granule.
GO:0031093	platelet alpha granule lumen	cellular_component	The volume enclosed by the membrane of the platelet alpha granule.
GO:0031094	platelet dense tubular network	cellular_component	A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.
GO:0031095	platelet dense tubular network membrane	cellular_component	The lipid bilayer surrounding the platelet dense tubular network.
GO:0031096	platelet dense tubular network lumen	cellular_component	The volume enclosed by the membranes of the platelet dense tubular network.
GO:0031097	medial cortex	cellular_component	A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
GO:0031098	stress-activated protein kinase signaling cascade	biological_process	The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.
GO:0031099	regeneration	biological_process	The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).
GO:0031100	animal organ regeneration	biological_process	The regrowth of a lost or destroyed animal organ.
GO:0031101	fin regeneration	biological_process	The regrowth of fin tissue following its loss or destruction.
GO:0031102	neuron projection regeneration	biological_process	The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.
GO:0031103	axon regeneration	biological_process	The regrowth of axons following their loss or damage.
GO:0031104	dendrite regeneration	biological_process	The regrowth of dendrites in response to their loss or damage.
GO:0031105	septin complex	cellular_component	A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
GO:0031106	septin ring organization	biological_process	Control of the formation, spatial distribution, and breakdown of the septin ring.
GO:0031107	septin ring disassembly	biological_process	The controlled breakdown of a septin ring.
GO:0031108	holo-[acyl-carrier-protein] biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].
GO:0031109	microtubule polymerization or depolymerization	biological_process	Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
GO:0031110	regulation of microtubule polymerization or depolymerization	biological_process	Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
GO:0031111	negative regulation of microtubule polymerization or depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.
GO:0031112	positive regulation of microtubule polymerization or depolymerization	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.
GO:0031113	regulation of microtubule polymerization	biological_process	Any process that modulates the frequency, rate or extent of microtubule polymerization.
GO:0031114	regulation of microtubule depolymerization	biological_process	Any process that modulates the frequency, rate or extent of microtubule depolymerization.
GO:0031115	negative regulation of microtubule polymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
GO:0031116	positive regulation of microtubule polymerization	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
GO:0031117	positive regulation of microtubule depolymerization	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
GO:0031118	rRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
GO:0031119	tRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
GO:0031120	snRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
GO:0031121	equatorial microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.
GO:0031122	cytoplasmic microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
GO:0031123	RNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an RNA molecule.
GO:0031124	mRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an mRNA molecule.
GO:0031125	rRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an rRNA molecule.
GO:0031126	sno(s)RNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea.
GO:0031127	alpha-(1,2)-fucosyltransferase activity	molecular_function	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.
GO:0031128	developmental induction	biological_process	A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).
GO:0031129	inductive cell-cell signaling	biological_process	Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.
GO:0031131	reception of an inductive signal	biological_process	The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.
GO:0031132	serine 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-serine + NADP+ = L-alpha-formylglycine + 2 H+ + NADPH.
GO:0031133	regulation of axon diameter	biological_process	Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.
GO:0031134	sister chromatid biorientation	biological_process	The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
GO:0031137	regulation of conjugation with cellular fusion	biological_process	Any process that modulates the rate or frequency of conjugation with cellular fusion.
GO:0031138	negative regulation of conjugation with cellular fusion	biological_process	Any process that decreases the rate or frequency of conjugation with cellular fusion.
GO:0031139	positive regulation of conjugation with cellular fusion	biological_process	Any process that increases the rate or frequency of conjugation with cellular fusion.
GO:0031140	induction of conjugation upon nutrient starvation	biological_process	The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.
GO:0031141	induction of conjugation upon carbon starvation	biological_process	The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.
GO:0031142	induction of conjugation upon nitrogen starvation	biological_process	The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.
GO:0031143	pseudopodium	cellular_component	A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.
GO:0031144	proteasome localization	biological_process	Any process in which the proteasome is transported to, or maintained in, a specific location.
GO:0031145	anaphase-promoting complex-dependent catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
GO:0031147	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process	biological_process	The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
GO:0031148	DIF-1 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
GO:0031149	sorocarp stalk cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
GO:0031150	sorocarp stalk development	biological_process	The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.
GO:0031151	histone H3K79 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group to the lysine residue at position 79 of the histone H3 protein.
GO:0031152	aggregation involved in sorocarp development	biological_process	The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
GO:0031153	slug development involved in sorocarp development	biological_process	The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.
GO:0031154	culmination involved in sorocarp development	biological_process	The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
GO:0031155	regulation of reproductive fruiting body development	biological_process	Any process that modulates the frequency, rate or extent of reproductive fruiting body development.
GO:0031156	regulation of sorocarp development	biological_process	Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.
GO:0031157	regulation of aggregate size involved in sorocarp development	biological_process	Any process that modulates the size of the aggregate formed during sorocarp formation.
GO:0031158	negative regulation of aggregate size involved in sorocarp development	biological_process	Any process that decreases the size of the aggregate formed during sorocarp formation.
GO:0031159	positive regulation of aggregate size involved in sorocarp development	biological_process	Any process that increases the size of the aggregate formed during sorocarp formation.
GO:0031160	spore wall	cellular_component	The specialized envelope lying outside the cell membrane of a spore.
GO:0031161	phosphatidylinositol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0031162	sulfur incorporation into metallo-sulfur cluster	biological_process	The incorporation of exogenous sulfur into a metallo-sulfur cluster.
GO:0031163	metallo-sulfur cluster assembly	biological_process	The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.
GO:0031164	contractile vacuolar membrane	cellular_component	The lipid bilayer surrounding the contractile vacuole.
GO:0031167	rRNA methylation	biological_process	The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
GO:0031168	ferrichrome metabolic process	biological_process	The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
GO:0031169	ferrichrome biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
GO:0031170	ferricrocin metabolic process	biological_process	The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.
GO:0031171	ferricrocin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.
GO:0031172	ornithine N5-monooxygenase activity	molecular_function	Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.
GO:0031173	otolith mineralization completed early in development	biological_process	The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.
GO:0031174	lifelong otolith mineralization	biological_process	The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.
GO:0031175	neuron projection development	biological_process	The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
GO:0031176	endo-1,4-beta-xylanase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
GO:0031177	phosphopantetheine binding	molecular_function	Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).
GO:0031179	peptide modification	biological_process	The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.
GO:0031201	SNARE complex	cellular_component	A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
GO:0031203	post-translational protein targeting to membrane, docking	biological_process	The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex.
GO:0031204	post-translational protein targeting to membrane, translocation	biological_process	The process in which a protein translocates through the ER membrane posttranslationally.
GO:0031205	endoplasmic reticulum Sec complex	cellular_component	An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex.
GO:0031207	Sec62/Sec63 complex	cellular_component	A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
GO:0031208	POZ domain binding	molecular_function	Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.
GO:0031209	SCAR complex	cellular_component	A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
GO:0031210	phosphatidylcholine binding	molecular_function	Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0031211	endoplasmic reticulum palmitoyltransferase complex	cellular_component	A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue.
GO:0031213	RSF complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).
GO:0031214	biomineral tissue development	biological_process	Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.
GO:0031215	shell calcification	biological_process	The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell.
GO:0031216	neopullulanase activity	molecular_function	Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).
GO:0031217	glucan 1,4-beta-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.
GO:0031218	arabinogalactan endo-1,4-beta-galactosidase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.
GO:0031219	levanase activity	molecular_function	Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.
GO:0031220	maltodextrin phosphorylase activity	molecular_function	Catalysis of the reaction: maltodextrin = glucose-1-phosphate.
GO:0031221	arabinan metabolic process	biological_process	The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.
GO:0031222	arabinan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.
GO:0031223	auditory behavior	biological_process	The behavior of an organism in response to a sound.
GO:0031232	extrinsic component of external side of plasma membrane	cellular_component	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	cellular_component	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
GO:0031236	extrinsic component of periplasmic side of plasma membrane	cellular_component	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region.
GO:0031240	external side of cell outer membrane	cellular_component	The side of the outer membrane that is opposite to the side that faces the periplasm of the cell.
GO:0031241	periplasmic side of cell outer membrane	cellular_component	The side (leaflet) of the outer membrane that faces the periplasm of the cell.
GO:0031242	extrinsic component of external side of cell outer membrane	cellular_component	The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
GO:0031244	extrinsic component of cell outer membrane	cellular_component	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031245	extrinsic component of periplasmic side of cell outer membrane	cellular_component	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region.
GO:0031247	actin rod assembly	biological_process	The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.
GO:0031248	protein acetyltransferase complex	cellular_component	A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.
GO:0031249	denatured protein binding	molecular_function	Binding to a denatured protein.
GO:0031250	anaerobic ribonucleoside-triphosphate reductase complex	cellular_component	An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.
GO:0031251	PAN complex	cellular_component	A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
GO:0031252	cell leading edge	cellular_component	The area of a motile cell closest to the direction of movement.
GO:0031253	cell projection membrane	cellular_component	The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.
GO:0031254	cell trailing edge	cellular_component	The area of a motile cell opposite to the direction of movement.
GO:0031255	lateral part of motile cell	cellular_component	The area of a motile cell perpendicular to the direction of movement.
GO:0031256	leading edge membrane	cellular_component	The portion of the plasma membrane surrounding the leading edge of a motile cell.
GO:0031257	cell trailing edge membrane	cellular_component	The portion of the plasma membrane surrounding the trailing edge of a motile cell.
GO:0031258	lamellipodium membrane	cellular_component	The portion of the plasma membrane surrounding a lamellipodium.
GO:0031259	uropod membrane	cellular_component	The portion of the plasma membrane surrounding a uropod.
GO:0031260	pseudopodium membrane	cellular_component	The portion of the plasma membrane surrounding a pseudopodium.
GO:0031261	DNA replication preinitiation complex	cellular_component	A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
GO:0031262	Ndc80 complex	cellular_component	An essential outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis.
GO:0031264	death-inducing signaling complex	cellular_component	A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
GO:0031265	CD95 death-inducing signaling complex	cellular_component	A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
GO:0031266	TRAIL death-inducing signaling complex	cellular_component	A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.
GO:0031267	small GTPase binding	molecular_function	Binding to a small monomeric GTPase.
GO:0031268	pseudopodium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.
GO:0031269	pseudopodium assembly	biological_process	The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.
GO:0031270	pseudopodium retraction	biological_process	The myosin-based contraction and retraction of a pseudopodium.
GO:0031271	lateral pseudopodium assembly	biological_process	The extension of a pseudopodium from the lateral area of a cell.
GO:0031272	regulation of pseudopodium assembly	biological_process	Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.
GO:0031273	negative regulation of pseudopodium assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.
GO:0031274	positive regulation of pseudopodium assembly	biological_process	Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.
GO:0031278	alpha-1,2-galactosyltransferase activity	molecular_function	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.
GO:0031279	regulation of cyclase activity	biological_process	Any process that modulates the frequency, rate or extent of cyclase activity.
GO:0031280	negative regulation of cyclase activity	biological_process	Any process that stops or reduces the activity of a cyclase.
GO:0031281	positive regulation of cyclase activity	biological_process	Any process that activates or increases the activity of a cyclase.
GO:0031282	regulation of guanylate cyclase activity	biological_process	Any process that modulates the frequency, rate or extent of guanylate cyclase activity.
GO:0031283	negative regulation of guanylate cyclase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.
GO:0031284	positive regulation of guanylate cyclase activity	biological_process	Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.
GO:0031285	regulation of sorocarp stalk cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
GO:0031286	negative regulation of sorocarp stalk cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
GO:0031287	positive regulation of sorocarp stalk cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
GO:0031288	sorocarp morphogenesis	biological_process	The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
GO:0031289	actin phosphorylation	biological_process	The transfer of one or more phosphate groups to an actin molecule.
GO:0031290	retinal ganglion cell axon guidance	biological_process	The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
GO:0031291	Ran protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state.
GO:0031293	membrane protein intracellular domain proteolysis	biological_process	The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
GO:0031294	lymphocyte costimulation	biological_process	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.
GO:0031295	T cell costimulation	biological_process	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
GO:0031296	B cell costimulation	biological_process	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.
GO:0031297	replication fork processing	biological_process	The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
GO:0031298	replication fork protection complex	cellular_component	A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.
GO:0031299	taurine-pyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.
GO:0031312	extrinsic component of organelle membrane	cellular_component	The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031313	extrinsic component of endosome membrane	cellular_component	The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031314	extrinsic component of mitochondrial inner membrane	cellular_component	The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031315	extrinsic component of mitochondrial outer membrane	cellular_component	The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031316	extrinsic component of nuclear outer membrane	cellular_component	The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031317	tripartite ATP-independent periplasmic transporter complex	cellular_component	A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients.
GO:0031318	detection of folic acid	biological_process	The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.
GO:0031319	detection of cAMP	biological_process	The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.
GO:0031320	hexitol dehydrogenase activity	molecular_function	Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.
GO:0031321	ascospore-type prospore assembly	biological_process	During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.
GO:0031322	ascospore-type prospore-specific spindle pole body remodeling	biological_process	A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).
GO:0031323	regulation of cellular metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0031324	negative regulation of cellular metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0031325	positive regulation of cellular metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0031326	regulation of cellular biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0031327	negative regulation of cellular biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0031328	positive regulation of cellular biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0031329	regulation of cellular catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GO:0031330	negative regulation of cellular catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GO:0031331	positive regulation of cellular catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GO:0031332	RNAi effector complex	cellular_component	Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.
GO:0031333	negative regulation of protein-containing complex assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
GO:0031334	positive regulation of protein-containing complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of protein complex assembly.
GO:0031335	regulation of sulfur amino acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
GO:0031336	negative regulation of sulfur amino acid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
GO:0031337	positive regulation of sulfur amino acid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
GO:0031338	regulation of vesicle fusion	biological_process	Any process that modulates the frequency, rate or extent of vesicle fusion.
GO:0031339	negative regulation of vesicle fusion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
GO:0031340	positive regulation of vesicle fusion	biological_process	Any process that activates or increases the frequency, rate or extent of vesicle fusion.
GO:0031341	regulation of cell killing	biological_process	Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.
GO:0031342	negative regulation of cell killing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
GO:0031343	positive regulation of cell killing	biological_process	Any process that activates or increases the frequency, rate or extent of cell killing.
GO:0031344	regulation of cell projection organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GO:0031345	negative regulation of cell projection organization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GO:0031346	positive regulation of cell projection organization	biological_process	Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GO:0031347	regulation of defense response	biological_process	Any process that modulates the frequency, rate or extent of a defense response.
GO:0031348	negative regulation of defense response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GO:0031349	positive regulation of defense response	biological_process	Any process that activates or increases the frequency, rate or extent of a defense response.
GO:0031363	N-terminal protein amino acid deamination	biological_process	The removal of an amino group from the N-terminal amino acid residue of a protein.
GO:0031364	N-terminal protein amino acid deamination, from side chain	biological_process	The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.
GO:0031365	N-terminal protein amino acid modification	biological_process	The alteration of the N-terminal amino acid residue in a protein.
GO:0031366	N-terminal peptidyl-asparagine deamination	biological_process	The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein.
GO:0031367	N-terminal peptidyl-glutamine deamination	biological_process	The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein.
GO:0031369	translation initiation factor binding	molecular_function	Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
GO:0031370	eukaryotic initiation factor 4G binding	molecular_function	Binding to eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.
GO:0031371	ubiquitin conjugating enzyme complex	cellular_component	Any complex that possesses ubiquitin conjugating enzyme activity.
GO:0031372	UBC13-MMS2 complex	cellular_component	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p.
GO:0031379	RNA-directed RNA polymerase complex	cellular_component	A protein complex that possesses RNA-directed RNA polymerase activity.
GO:0031380	nuclear RNA-directed RNA polymerase complex	cellular_component	A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.
GO:0031381	viral RNA-directed RNA polymerase complex	cellular_component	A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus.
GO:0031382	mating projection formation	biological_process	The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.
GO:0031383	regulation of mating projection assembly	biological_process	Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi.
GO:0031384	regulation of initiation of mating projection growth	biological_process	Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.
GO:0031385	regulation of termination of mating projection growth	biological_process	Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.
GO:0031386	protein tag activity	molecular_function	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.
GO:0031387	MPF complex	cellular_component	A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).
GO:0031388	organic acid phosphorylation	biological_process	The process of introducing one or more phosphate groups into an organic acid.
GO:0031389	Rad17 RFC-like complex	cellular_component	A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
GO:0031390	Ctf18 RFC-like complex	cellular_component	A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p.
GO:0031391	Elg1 RFC-like complex	cellular_component	A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
GO:0031392	regulation of prostaglandin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
GO:0031393	negative regulation of prostaglandin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
GO:0031394	positive regulation of prostaglandin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
GO:0031395	bursicon neuropeptide hormone complex	cellular_component	A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits.
GO:0031396	regulation of protein ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.
GO:0031397	negative regulation of protein ubiquitination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
GO:0031398	positive regulation of protein ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
GO:0031399	regulation of protein modification process	biological_process	Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GO:0031400	negative regulation of protein modification process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GO:0031401	positive regulation of protein modification process	biological_process	Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GO:0031402	sodium ion binding	molecular_function	Binding to a sodium ion (Na+).
GO:0031403	lithium ion binding	molecular_function	Binding to a lithium ion (Li+).
GO:0031404	chloride ion binding	molecular_function	Binding to a chloride ion (Cl-).
GO:0031405	lipoic acid binding	molecular_function	Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.
GO:0031406	carboxylic acid binding	molecular_function	Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0031407	oxylipin metabolic process	biological_process	The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
GO:0031408	oxylipin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
GO:0031409	pigment binding	molecular_function	Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.
GO:0031410	cytoplasmic vesicle	cellular_component	A vesicle found in the cytoplasm of a cell.
GO:0031411	gas vesicle	cellular_component	An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.
GO:0031412	gas vesicle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps.
GO:0031413	regulation of buoyancy	biological_process	Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases.
GO:0031414	N-terminal protein acetyltransferase complex	cellular_component	A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.
GO:0031415	NatA complex	cellular_component	A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.
GO:0031416	NatB complex	cellular_component	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p.
GO:0031417	NatC complex	cellular_component	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.
GO:0031418	L-ascorbic acid binding	molecular_function	Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
GO:0031419	cobalamin binding	molecular_function	Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GO:0031420	alkali metal ion binding	molecular_function	Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.
GO:0031421	invertasome	cellular_component	A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.
GO:0031422	RecQ family helicase-topoisomerase III complex	cellular_component	A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human.
GO:0031423	hexon binding	molecular_function	Binding to a hexon, the major protein component of the icosahedral capsid of an adenovirus.
GO:0031424	keratinization	biological_process	The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.
GO:0031425	chloroplast RNA processing	biological_process	The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.
GO:0031426	polycistronic mRNA processing	biological_process	The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.
GO:0031427	response to methotrexate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
GO:0031428	box C/D RNP complex	cellular_component	A ribonucleoprotein complex containing a box C/D type RNA that can carry out ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.
GO:0031429	box H/ACA snoRNP complex	cellular_component	A box H/ACA RNP complex that is located in the nucleolus.
GO:0031430	M band	cellular_component	The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.
GO:0031431	Dbf4-dependent protein kinase complex	cellular_component	A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.
GO:0031432	titin binding	molecular_function	Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
GO:0031433	telethonin binding	molecular_function	Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.
GO:0031434	mitogen-activated protein kinase kinase binding	molecular_function	Binding to a mitogen-activated protein kinase kinase, a protein that can phosphorylate a MAP kinase.
GO:0031435	mitogen-activated protein kinase kinase kinase binding	molecular_function	Binding to a mitogen-activated protein kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase.
GO:0031436	BRCA1-BARD1 complex	cellular_component	A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.
GO:0031440	regulation of mRNA 3'-end processing	biological_process	Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
GO:0031441	negative regulation of mRNA 3'-end processing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.
GO:0031442	positive regulation of mRNA 3'-end processing	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
GO:0031443	fast-twitch skeletal muscle fiber contraction	biological_process	A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
GO:0031444	slow-twitch skeletal muscle fiber contraction	biological_process	A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
GO:0031445	regulation of heterochromatin formation	biological_process	Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction	biological_process	Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.
GO:0031447	negative regulation of fast-twitch skeletal muscle fiber contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	biological_process	Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.
GO:0031449	regulation of slow-twitch skeletal muscle fiber contraction	biological_process	Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.
GO:0031450	negative regulation of slow-twitch skeletal muscle fiber contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.
GO:0031451	positive regulation of slow-twitch skeletal muscle fiber contraction	biological_process	Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.
GO:0031452	negative regulation of heterochromatin formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
GO:0031453	positive regulation of heterochromatin formation	biological_process	Any process that activates or increases the frequency, rate or extent of heterochromatin formation.
GO:0031455	glycine betaine metabolic process	biological_process	The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.
GO:0031456	glycine betaine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.
GO:0031457	glycine betaine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.
GO:0031458	ABC-type betaine transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).
GO:0031459	ABC-type glycine betaine transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).
GO:0031460	glycine betaine transport	biological_process	The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0031461	cullin-RING ubiquitin ligase complex	cellular_component	Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.
GO:0031462	Cul2-RING ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
GO:0031463	Cul3-RING ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.
GO:0031466	Cul5-RING ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
GO:0031467	Cul7-RING ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.
GO:0031468	nuclear membrane reassembly	biological_process	The reformation of the nuclear membranes following their breakdown in the context of a normal process.
GO:0031469	bacterial microcompartment	cellular_component	An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
GO:0031470	carboxysome	cellular_component	An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO2. It augments the concentration of CO2 in the vicinity of RuBisCO to increase the efficiency of CO2 fixation under atmospheric conditions.
GO:0031471	ethanolamine degradation polyhedral organelle	cellular_component	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.
GO:0031472	propanediol degradation polyhedral organelle	cellular_component	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.
GO:0031473	myosin III binding	molecular_function	Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
GO:0031474	myosin IV complex	cellular_component	A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.
GO:0031475	myosin V complex	cellular_component	A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.
GO:0031476	myosin VI complex	cellular_component	A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
GO:0031477	myosin VII complex	cellular_component	A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.
GO:0031478	myosin VIII complex	cellular_component	A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.
GO:0031479	myosin IX complex	cellular_component	A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.
GO:0031480	myosin X complex	cellular_component	A myosin complex containing one or more class X myosin heavy chains and associated light chains.
GO:0031481	myosin XI complex	cellular_component	A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.
GO:0031482	myosin XII complex	cellular_component	A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.
GO:0031483	myosin XIII complex	cellular_component	A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.
GO:0031484	myosin XIV complex	cellular_component	A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
GO:0031485	myosin XV complex	cellular_component	A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.
GO:0031486	myosin XVI complex	cellular_component	A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.
GO:0031487	myosin XVII complex	cellular_component	A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.
GO:0031488	myosin XVIII complex	cellular_component	A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.
GO:0031489	myosin V binding	molecular_function	Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
GO:0031490	chromatin DNA binding	molecular_function	Binding to DNA that is assembled into chromatin.
GO:0031491	nucleosome binding	molecular_function	Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
GO:0031492	nucleosomal DNA binding	molecular_function	Binding to the DNA portion of a nucleosome.
GO:0031494	regulation of mating type switching	biological_process	Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.
GO:0031495	negative regulation of mating type switching	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.
GO:0031496	positive regulation of mating type switching	biological_process	Any process that activates or increases the frequency, rate or extent of mating type switching.
GO:0031499	TRAMP complex	cellular_component	A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
GO:0031500	Tea1 cell-end complex	cellular_component	A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
GO:0031501	mannosyltransferase complex	cellular_component	A complex that posseses mannosyltransferase activity.
GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex	cellular_component	A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.
GO:0031503	protein-containing complex localization	biological_process	A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
GO:0031504	peptidoglycan-based cell wall organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.
GO:0031505	fungal-type cell wall organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
GO:0031506	cell wall glycoprotein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.
GO:0031507	heterochromatin formation	biological_process	An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
GO:0031508	pericentric heterochromatin formation	biological_process	The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.
GO:0031509	subtelomeric heterochromatin formation	biological_process	The compaction of chromatin into heterochromatin at the subtelomeric region.
GO:0031510	SUMO activating enzyme complex	cellular_component	A conserved heterodimeric complex with SUMO activating enzyme activity.
GO:0031511	Mis6-Sim4 complex	cellular_component	A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.
GO:0031514	motile cilium	cellular_component	A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
GO:0031515	tRNA (m1A) methyltransferase complex	cellular_component	A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.
GO:0031516	far-red light photoreceptor activity	molecular_function	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.
GO:0031517	red light photoreceptor activity	molecular_function	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.
GO:0031518	CBF3 complex	cellular_component	A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.
GO:0031519	PcG protein complex	cellular_component	A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
GO:0031520	plasma membrane of cell tip	cellular_component	The portion of the plasma membrane surrounding the cell tip.
GO:0031521	spitzenkorper	cellular_component	Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
GO:0031522	cell envelope Sec protein transport complex	cellular_component	A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
GO:0031523	Myb complex	cellular_component	A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.
GO:0031524	menthol metabolic process	biological_process	The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
GO:0031525	menthol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
GO:0031526	brush border membrane	cellular_component	The portion of the plasma membrane surrounding the brush border.
GO:0031527	filopodium membrane	cellular_component	The portion of the plasma membrane surrounding a filopodium.
GO:0031528	microvillus membrane	cellular_component	The portion of the plasma membrane surrounding a microvillus.
GO:0031529	ruffle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
GO:0031530	gonadotropin-releasing hormone receptor binding	molecular_function	Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
GO:0031531	thyrotropin-releasing hormone receptor binding	molecular_function	Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.
GO:0031533	mRNA cap methyltransferase complex	cellular_component	A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
GO:0031534	minus-end directed microtubule sliding	biological_process	The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
GO:0031535	plus-end directed microtubule sliding	biological_process	The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.
GO:0031536	positive regulation of exit from mitosis	biological_process	Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
GO:0031537	regulation of anthocyanin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
GO:0031538	negative regulation of anthocyanin metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
GO:0031539	positive regulation of anthocyanin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
GO:0031540	regulation of anthocyanin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
GO:0031541	negative regulation of anthocyanin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
GO:0031542	positive regulation of anthocyanin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
GO:0031543	peptidyl-proline dioxygenase activity	molecular_function	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.
GO:0031544	peptidyl-proline 3-dioxygenase activity	molecular_function	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.
GO:0031545	peptidyl-proline 4-dioxygenase activity	molecular_function	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.
GO:0031546	brain-derived neurotrophic factor receptor binding	molecular_function	Binding to a brain-derived neurotrophic factor receptor.
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.
GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
GO:0031549	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
GO:0031550	positive regulation of brain-derived neurotrophic factor receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
GO:0031551	regulation of brain-derived neurotrophic factor-activated receptor activity	biological_process	Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
GO:0031552	negative regulation of brain-derived neurotrophic factor-activated receptor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
GO:0031553	positive regulation of brain-derived neurotrophic factor-activated receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
GO:0031554	regulation of termination of DNA-templated transcription	biological_process	Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
GO:0031555	transcriptional attenuation	biological_process	A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.
GO:0031556	transcriptional attenuation by ribosome	biological_process	A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.
GO:0031559	oxidosqualene cyclase activity	molecular_function	Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
GO:0031560	cellular bud neck polarisome	cellular_component	Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
GO:0031561	cellular bud tip polarisome	cellular_component	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
GO:0031562	hyphal tip polarisome	cellular_component	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
GO:0031563	mating projection tip polarisome	cellular_component	Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.
GO:0031564	transcription antitermination	biological_process	A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.
GO:0031566	actomyosin contractile ring maturation	biological_process	The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.
GO:0031567	mitotic cell size control checkpoint signaling	biological_process	A signal transduction process that contributes to a cell size control checkpoint during mitosis.
GO:0031568	mitotic G1 cell size control checkpoint signaling	biological_process	A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.
GO:0031569	mitotic G2 cell size control checkpoint signaling	biological_process	A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.
GO:0031570	DNA integrity checkpoint signaling	biological_process	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
GO:0031571	mitotic G1 DNA damage checkpoint signaling	biological_process	A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	biological_process	A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.
GO:0031577	spindle checkpoint signaling	biological_process	A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.
GO:0031578	mitotic spindle orientation checkpoint signaling	biological_process	A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.
GO:0031579	membrane raft organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
GO:0031580	membrane raft distribution	biological_process	The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.
GO:0031581	hemidesmosome assembly	biological_process	Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
GO:0031582	replication fork arrest at rDNA repeats	biological_process	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.
GO:0031583	phospholipase D-activating G protein-coupled receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase D (PLD) and a subsequent increase in the intracellular concentration of phosphatidic acid (PA).
GO:0031584	activation of phospholipase D activity	biological_process	Any process that initiates the activity of inactive phospholipase D.
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	biological_process	Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
GO:0031586	negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
GO:0031588	nucleotide-activated protein kinase complex	cellular_component	A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
GO:0031589	cell-substrate adhesion	biological_process	The attachment of a cell to the underlying substrate via adhesion molecules.
GO:0031590	wybutosine metabolic process	biological_process	The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
GO:0031591	wybutosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
GO:0031592	centrosomal corona	cellular_component	An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.
GO:0031593	polyubiquitin modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ubiquitination of the target protein.
GO:0031594	neuromuscular junction	cellular_component	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
GO:0031595	nuclear proteasome complex	cellular_component	A proteasome found in the nucleus of a cell.
GO:0031597	cytosolic proteasome complex	cellular_component	A proteasome complex found in the cytosol of a cell.
GO:0031598	nuclear proteasome regulatory particle	cellular_component	The regulatory subcomplex of a proteasome located in the nucleus of a cell.
GO:0031600	cytosolic proteasome regulatory particle	cellular_component	A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.
GO:0031601	nuclear proteasome core complex	cellular_component	The core complex of a proteasome located in the nucleus of a cell.
GO:0031603	cytosolic proteasome core complex	cellular_component	The core complex of a proteasome located in the cytosol of a cell.
GO:0031604	nuclear proteasome core complex, alpha-subunit complex	cellular_component	The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.
GO:0031606	cytosolic proteasome core complex, alpha-subunit complex	cellular_component	The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.
GO:0031607	nuclear proteasome core complex, beta-subunit complex	cellular_component	The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.
GO:0031609	cytosolic proteasome core complex, beta-subunit complex	cellular_component	The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.
GO:0031610	nuclear proteasome regulatory particle, base subcomplex	cellular_component	The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.
GO:0031612	cytosolic proteasome regulatory particle, base subcomplex	cellular_component	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.
GO:0031613	nuclear proteasome regulatory particle, lid subcomplex	cellular_component	The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.
GO:0031615	cytosolic proteasome regulatory particle, lid subcomplex	cellular_component	The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.
GO:0031616	spindle pole centrosome	cellular_component	A centrosome from which one pole of a mitotic or meiotic spindle is organized.
GO:0031619	homologous chromosome orientation in meiotic metaphase I	biological_process	The cell cycle process in which the sister centromeres and kinetochores of one chromosome are fused and orientated so the chromosomes attach to microtubules that emanate from the same spindle pole. This process ensures that homologous l chromosomes are segregated at anaphase of meiosis I.
GO:0031620	regulation of fever generation	biological_process	Any process that modulates the rate or extent of fever generation.
GO:0031621	negative regulation of fever generation	biological_process	Any process that stops, prevents, or reduces the rate or extent of fever generation.
GO:0031622	positive regulation of fever generation	biological_process	Any process that activates or increases the frequency, rate, or extent of fever generation.
GO:0031623	receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
GO:0031624	ubiquitin conjugating enzyme binding	molecular_function	Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.
GO:0031625	ubiquitin protein ligase binding	molecular_function	Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.
GO:0031626	beta-endorphin binding	molecular_function	Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.
GO:0031627	telomeric loop formation	biological_process	The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.
GO:0031628	opioid receptor binding	molecular_function	Binding to an opioid receptor.
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	biological_process	Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
GO:0031631	negative regulation of synaptic vesicle fusion to presynaptic active zone membrane	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
GO:0031632	positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
GO:0031633	xanthophore	cellular_component	A chromatophore containing yellow pigment.
GO:0031634	replication fork barrier binding	molecular_function	Binding to replication fork barriers, sites that inhibit the progress of replication forks.
GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0031637	regulation of neuronal synaptic plasticity in response to neurotrophin	biological_process	The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
GO:0031638	zymogen activation	biological_process	The proteolytic processing of an inactive enzyme to an active form.
GO:0031639	plasminogen activation	biological_process	The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
GO:0031640	killing of cells of another organism	biological_process	Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0031641	regulation of myelination	biological_process	Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
GO:0031642	negative regulation of myelination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
GO:0031643	positive regulation of myelination	biological_process	Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
GO:0031644	regulation of nervous system process	biological_process	Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
GO:0031645	negative regulation of nervous system process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
GO:0031646	positive regulation of nervous system process	biological_process	Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
GO:0031647	regulation of protein stability	biological_process	Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
GO:0031648	protein destabilization	biological_process	Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
GO:0031649	heat generation	biological_process	Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
GO:0031650	regulation of heat generation	biological_process	Any process that modulates the rate or extent of heat generation.
GO:0031651	negative regulation of heat generation	biological_process	Any process that stops, prevents, or reduces the rate or extent of heat generation.
GO:0031652	positive regulation of heat generation	biological_process	Any process that activates or increases the rate or extent of heat generation.
GO:0031653	heat dissipation	biological_process	Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.
GO:0031654	regulation of heat dissipation	biological_process	Any process that modulates the rate or extent of heat dissipation.
GO:0031655	negative regulation of heat dissipation	biological_process	Any process that stops, prevents, or reduces the rate or extent of heat dissipation.
GO:0031656	positive regulation of heat dissipation	biological_process	Any process that activates or increases the rate or extent of heat dissipation.
GO:0031663	lipopolysaccharide-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
GO:0031667	response to nutrient levels	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
GO:0031668	cellular response to extracellular stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
GO:0031669	cellular response to nutrient levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
GO:0031670	cellular response to nutrient	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
GO:0031671	primary cell septum biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.
GO:0031672	A band	cellular_component	The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
GO:0031673	H zone	cellular_component	A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.
GO:0031674	I band	cellular_component	A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
GO:0031676	plasma membrane-derived thylakoid membrane	cellular_component	The pigmented membrane of a plasma membrane-derived thylakoid.
GO:0031679	NADH dehydrogenase (plastoquinone) activity	molecular_function	Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.
GO:0031680	G-protein beta/gamma-subunit complex	cellular_component	The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.
GO:0031681	G-protein beta-subunit binding	molecular_function	Binding to a G-protein beta subunit.
GO:0031682	G-protein gamma-subunit binding	molecular_function	Binding to a G-protein gamma subunit.
GO:0031683	G-protein beta/gamma-subunit complex binding	molecular_function	Binding to a complex of G-protein beta/gamma subunits.
GO:0031685	adenosine receptor binding	molecular_function	Binding to an adenosine receptor.
GO:0031686	A1 adenosine receptor binding	molecular_function	Binding to an A1 adenosine receptor.
GO:0031687	A2A adenosine receptor binding	molecular_function	Binding to an A2A adenosine receptor.
GO:0031688	A2B adenosine receptor binding	molecular_function	Binding to an A2B adenosine receptor.
GO:0031689	A3 adenosine receptor binding	molecular_function	Binding to an A3 adenosine receptor.
GO:0031690	adrenergic receptor binding	molecular_function	Binding to an adrenergic receptor.
GO:0031691	alpha-1A adrenergic receptor binding	molecular_function	Binding to an alpha-1A adrenergic receptor.
GO:0031692	alpha-1B adrenergic receptor binding	molecular_function	Binding to an alpha-1B adrenergic receptor.
GO:0031693	alpha-1D adrenergic receptor binding	molecular_function	Binding to an alpha-1D adrenergic receptor.
GO:0031694	alpha-2A adrenergic receptor binding	molecular_function	Binding to an alpha-2A adrenergic receptor.
GO:0031695	alpha-2B adrenergic receptor binding	molecular_function	Binding to an alpha-2B adrenergic receptor.
GO:0031696	alpha-2C adrenergic receptor binding	molecular_function	Binding to an alpha-2C adrenergic receptor.
GO:0031697	beta-1 adrenergic receptor binding	molecular_function	Binding to a beta-1 adrenergic receptor.
GO:0031698	beta-2 adrenergic receptor binding	molecular_function	Binding to a beta-2 adrenergic receptor.
GO:0031699	beta-3 adrenergic receptor binding	molecular_function	Binding to a beta-3 adrenergic receptor.
GO:0031700	adrenomedullin receptor binding	molecular_function	Binding to an adrenomedullin receptor.
GO:0031701	angiotensin receptor binding	molecular_function	Binding to an angiotensin receptor.
GO:0031702	type 1 angiotensin receptor binding	molecular_function	Binding to a type 1 angiotensin receptor.
GO:0031703	type 2 angiotensin receptor binding	molecular_function	Binding to a type 2 angiotensin receptor.
GO:0031704	apelin receptor binding	molecular_function	Binding to an apelin receptor.
GO:0031705	bombesin receptor binding	molecular_function	Binding to a bombesin receptor.
GO:0031706	subtype 3 bombesin receptor binding	molecular_function	Binding to a subtype 3 bombesin receptor.
GO:0031707	endothelin A receptor binding	molecular_function	Binding to an endothelin A receptor.
GO:0031708	endothelin B receptor binding	molecular_function	Binding to an endothelin B receptor.
GO:0031709	gastrin-releasing peptide receptor binding	molecular_function	Binding to a gastrin-releasing peptide receptor.
GO:0031710	neuromedin B receptor binding	molecular_function	Binding to a neuromedin B receptor.
GO:0031711	bradykinin receptor binding	molecular_function	Binding to a bradykinin receptor.
GO:0031712	B1 bradykinin receptor binding	molecular_function	Binding to a B1 bradykinin receptor.
GO:0031713	B2 bradykinin receptor binding	molecular_function	Binding to a B2 bradykinin receptor.
GO:0031714	C5a anaphylatoxin chemotactic receptor binding	molecular_function	Binding to a C5a anaphylatoxin chemotactic receptor.
GO:0031715	C5L2 anaphylatoxin chemotactic receptor binding	molecular_function	Binding to a C5L2 anaphylatoxin chemotactic receptor.
GO:0031716	calcitonin receptor binding	molecular_function	Binding to a calcitonin receptor.
GO:0031717	cannabinoid receptor binding	molecular_function	Binding to a cannabinoid receptor.
GO:0031718	type 1 cannabinoid receptor binding	molecular_function	Binding to a type 1 cannabinoid receptor.
GO:0031719	type 2 cannabinoid receptor binding	molecular_function	Binding to a type 2 cannabinoid receptor.
GO:0031720	haptoglobin binding	molecular_function	Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
GO:0031721	hemoglobin alpha binding	molecular_function	Binding to a hemoglobin alpha chain.
GO:0031722	hemoglobin beta binding	molecular_function	Binding to a hemoglobin beta chain.
GO:0031723	CXCR4 chemokine receptor binding	molecular_function	Binding to a CXCR4 chemokine receptor.
GO:0031724	CXCR5 chemokine receptor binding	molecular_function	Binding to a CXCR5 chemokine receptor.
GO:0031725	CXCR6 chemokine receptor binding	molecular_function	Binding to a CXCR6 chemokine receptor.
GO:0031726	CCR1 chemokine receptor binding	molecular_function	Binding to a CCR1 chemokine receptor.
GO:0031727	CCR2 chemokine receptor binding	molecular_function	Binding to a CCR2 chemokine receptor.
GO:0031728	CCR3 chemokine receptor binding	molecular_function	Binding to a CCR3 chemokine receptor.
GO:0031729	CCR4 chemokine receptor binding	molecular_function	Binding to a CCR4 chemokine receptor.
GO:0031730	CCR5 chemokine receptor binding	molecular_function	Binding to a CCR5 chemokine receptor.
GO:0031731	CCR6 chemokine receptor binding	molecular_function	Binding to a CCR6 chemokine receptor.
GO:0031732	CCR7 chemokine receptor binding	molecular_function	Binding to a CCR7 chemokine receptor.
GO:0031733	CCR8 chemokine receptor binding	molecular_function	Binding to a CCR8 chemokine receptor.
GO:0031734	CCR9 chemokine receptor binding	molecular_function	Binding to a CCR9 chemokine receptor.
GO:0031735	CCR10 chemokine receptor binding	molecular_function	Binding to a CCR10 chemokine receptor.
GO:0031736	CCR11 chemokine receptor binding	molecular_function	Binding to a CCR11 chemokine receptor.
GO:0031737	CX3C chemokine receptor binding	molecular_function	Binding to a CX3C chemokine receptor.
GO:0031738	XCR1 chemokine receptor binding	molecular_function	Binding to a XCR1 chemokine receptor.
GO:0031739	cholecystokinin receptor binding	molecular_function	Binding to a cholecystokinin receptor.
GO:0031740	type A cholecystokinin receptor binding	molecular_function	Binding to a type A cholecystokinin receptor.
GO:0031741	type B gastrin/cholecystokinin receptor binding	molecular_function	Binding to a type B gastrin/cholecystokinin receptor.
GO:0031745	cysteinyl leukotriene receptor binding	molecular_function	Binding to a cysteinyl leukotriene receptor.
GO:0031746	type 1 cysteinyl leukotriene receptor binding	molecular_function	Binding to a type 1 cysteinyl leukotriene receptor.
GO:0031747	type 2 cysteinyl leukotriene receptor binding	molecular_function	Binding to a type 2 cysteinyl leukotriene receptor.
GO:0031748	D1 dopamine receptor binding	molecular_function	Binding to a D1 dopamine receptor.
GO:0031749	D2 dopamine receptor binding	molecular_function	Binding to a D2 dopamine receptor.
GO:0031750	D3 dopamine receptor binding	molecular_function	Binding to a D3 dopamine receptor.
GO:0031751	D4 dopamine receptor binding	molecular_function	Binding to a D4 dopamine receptor.
GO:0031752	D5 dopamine receptor binding	molecular_function	Binding to a D5 dopamine receptor.
GO:0031753	endothelial differentiation G protein-coupled receptor binding	molecular_function	Binding to an endothelial differentiation G protein-coupled receptor.
GO:0031754	Edg-1 sphingosine 1-phosphate receptor binding	molecular_function	Binding to an Edg-1 sphingosine 1-phosphate receptor.
GO:0031755	Edg-2 lysophosphatidic acid receptor binding	molecular_function	Binding to an Edg-2 lysophosphatidic acid receptor.
GO:0031756	Edg-3 sphingosine 1-phosphate receptor binding	molecular_function	Binding to an Edg-3 sphingosine 1-phosphate receptor.
GO:0031757	Edg-4 lysophosphatidic acid receptor binding	molecular_function	Binding to an Edg-4 lysophosphatidic acid receptor.
GO:0031758	Edg-5 sphingosine 1-phosphate receptor binding	molecular_function	Binding to an Edg-5 sphingosine 1-phosphate receptor.
GO:0031759	Edg-6 sphingosine 1-phosphate receptor binding	molecular_function	Binding to an Edg-6 sphingosine 1-phosphate receptor.
GO:0031760	Edg-7 lysophosphatidic acid receptor binding	molecular_function	Binding to an Edg-7 lysophosphatidic acid receptor.
GO:0031761	fMet-Leu-Phe receptor binding	molecular_function	Binding to a fMet-Leu-Phe receptor.
GO:0031762	follicle-stimulating hormone receptor binding	molecular_function	Binding to a follicle-stimulating hormone receptor.
GO:0031763	galanin receptor binding	molecular_function	Binding to a galanin receptor.
GO:0031764	type 1 galanin receptor binding	molecular_function	Binding to a type 1 galanin receptor.
GO:0031765	type 2 galanin receptor binding	molecular_function	Binding to a type 2 galanin receptor.
GO:0031766	type 3 galanin receptor binding	molecular_function	Binding to a type 3 galanin receptor.
GO:0031767	gastric inhibitory polypeptide receptor binding	molecular_function	Binding to a gastric inhibitory polypeptide receptor.
GO:0031768	ghrelin receptor binding	molecular_function	Binding to a ghrelin receptor.
GO:0031769	glucagon receptor binding	molecular_function	Binding to a glucagon receptor.
GO:0031770	growth hormone-releasing hormone receptor binding	molecular_function	Binding to a growth hormone-releasing hormone receptor.
GO:0031771	type 1 orexin receptor binding	molecular_function	Binding to a type 1 orexin receptor.
GO:0031772	type 2 orexin receptor binding	molecular_function	Binding to a type 2 orexin receptor.
GO:0031773	kisspeptin receptor binding	molecular_function	Binding to a kisspeptin receptor.
GO:0031774	leukotriene receptor binding	molecular_function	Binding to a leukotriene receptor.
GO:0031775	lutropin-choriogonadotropic hormone receptor binding	molecular_function	Binding to a lutropin-choriogonadotropic hormone receptor.
GO:0031776	melanin-concentrating hormone receptor binding	molecular_function	Binding to a melanin-concentrating hormone receptor.
GO:0031777	type 1 melanin-concentrating hormone receptor binding	molecular_function	Binding to a type 1 melanin-concentrating hormone receptor.
GO:0031778	type 2 melanin-concentrating hormone receptor binding	molecular_function	Binding to a type 2 melanin-concentrating hormone receptor.
GO:0031779	melanocortin receptor binding	molecular_function	Binding to a melanocortin receptor.
GO:0031780	corticotropin hormone receptor binding	molecular_function	Binding to a corticotropin hormone receptor.
GO:0031781	type 3 melanocortin receptor binding	molecular_function	Binding to a type 3 melanocortin receptor.
GO:0031782	type 4 melanocortin receptor binding	molecular_function	Binding to a type 4 melanocortin receptor.
GO:0031783	type 5 melanocortin receptor binding	molecular_function	Binding to a type 5 melanocortin receptor.
GO:0031784	melatonin receptor binding	molecular_function	Binding to a melatonin receptor.
GO:0031785	type 1A melatonin receptor binding	molecular_function	Binding to a type 1A melatonin receptor.
GO:0031786	type 1B melatonin receptor binding	molecular_function	Binding to a type 1B melatonin receptor.
GO:0031787	H9 melatonin receptor binding	molecular_function	Binding to a H9 melatonin receptor.
GO:0031788	motilin receptor binding	molecular_function	Binding to a motilin receptor.
GO:0031789	G protein-coupled acetylcholine receptor binding	molecular_function	Binding to a G protein-coupled acetylcholine receptor.
GO:0031795	G protein-coupled GABA receptor binding	molecular_function	Binding to a G protein-coupled (metabotropic) GABA receptor.
GO:0031796	type 1 metabotropic GABA receptor binding	molecular_function	Binding to a type 1 metabotropic GABA receptor.
GO:0031797	type 2 metabotropic GABA receptor binding	molecular_function	Binding to a type 2 metabotropic GABA receptor.
GO:0031798	type 1 metabotropic glutamate receptor binding	molecular_function	Binding to a type 1 metabotropic glutamate receptor.
GO:0031799	type 2 metabotropic glutamate receptor binding	molecular_function	Binding to a type 2 metabotropic glutamate receptor.
GO:0031800	type 3 metabotropic glutamate receptor binding	molecular_function	Binding to a type 3 metabotropic glutamate receptor.
GO:0031801	type 4 metabotropic glutamate receptor binding	molecular_function	Binding to a type 4 metabotropic glutamate receptor.
GO:0031802	type 5 metabotropic glutamate receptor binding	molecular_function	Binding to a type 5 metabotropic glutamate receptor.
GO:0031803	type 6 metabotropic glutamate receptor binding	molecular_function	Binding to a type 6 metabotropic glutamate receptor.
GO:0031804	type 7 metabotropic glutamate receptor binding	molecular_function	Binding to a type 7 metabotropic glutamate receptor.
GO:0031805	type 8 metabotropic glutamate receptor binding	molecular_function	Binding to a type 8 metabotropic glutamate receptor.
GO:0031806	G protein-coupled histamine receptor binding	molecular_function	Binding to a G protein-coupled (metabotropic) histamine receptor.
GO:0031807	H1 histamine receptor binding	molecular_function	Binding to a H1 histamine receptor.
GO:0031808	H2 histamine receptor binding	molecular_function	Binding to a H2 histamine receptor.
GO:0031809	H3 histamine receptor binding	molecular_function	Binding to a H3 histamine receptor.
GO:0031810	H4 histamine receptor binding	molecular_function	Binding to a H4 histamine receptor.
GO:0031811	G protein-coupled nucleotide receptor binding	molecular_function	Binding to a G protein-coupled (metabotropic) nucleotide receptor.
GO:0031812	P2Y1 nucleotide receptor binding	molecular_function	Binding to a P2Y1 nucleotide receptor.
GO:0031813	P2Y2 nucleotide receptor binding	molecular_function	Binding to a P2Y2 nucleotide receptor.
GO:0031814	P2Y4 nucleotide receptor binding	molecular_function	Binding to a P2Y4 nucleotide receptor.
GO:0031815	P2Y5 nucleotide receptor binding	molecular_function	Binding to a P2Y5 nucleotide receptor.
GO:0031816	P2Y6 nucleotide receptor binding	molecular_function	Binding to a P2Y6 nucleotide receptor.
GO:0031817	P2Y8 nucleotide receptor binding	molecular_function	Binding to a P2Y8 nucleotide receptor.
GO:0031818	P2Y9 nucleotide receptor binding	molecular_function	Binding to a P2Y9 nucleotide receptor.
GO:0031819	P2Y10 nucleotide receptor binding	molecular_function	Binding to a P2Y10 nucleotide receptor.
GO:0031820	P2Y11 nucleotide receptor binding	molecular_function	Binding to a P2Y11 nucleotide receptor.
GO:0031821	G protein-coupled serotonin receptor binding	molecular_function	Binding to a metabotropic serotonin receptor.
GO:0031822	type 1B serotonin receptor binding	molecular_function	Binding to a type 1B serotonin receptor.
GO:0031823	type 1D serotonin receptor binding	molecular_function	Binding to a type 1D serotonin receptor.
GO:0031824	type 1E serotonin receptor binding	molecular_function	Binding to a type 1E serotonin receptor.
GO:0031825	type 1F serotonin receptor binding	molecular_function	Binding to a type 1F serotonin receptor.
GO:0031826	type 2A serotonin receptor binding	molecular_function	Binding to a type 2A serotonin receptor.
GO:0031827	type 2B serotonin receptor binding	molecular_function	Binding to a type 2B serotonin receptor.
GO:0031828	type 2C serotonin receptor binding	molecular_function	Binding to a type 2C serotonin receptor.
GO:0031829	type 4 serotonin receptor binding	molecular_function	Binding to a type 4 serotonin receptor.
GO:0031830	type 5A serotonin receptor binding	molecular_function	Binding to a type 5A serotonin receptor.
GO:0031831	type 5B serotonin receptor binding	molecular_function	Binding to a type 5B serotonin receptor.
GO:0031832	type 6 serotonin receptor binding	molecular_function	Binding to a type 6 serotonin receptor.
GO:0031833	type 7 serotonin receptor binding	molecular_function	Binding to a type 7 serotonin receptor.
GO:0031834	neurokinin receptor binding	molecular_function	Binding to a neurokinin receptor.
GO:0031835	substance P receptor binding	molecular_function	Binding to a substance P receptor.
GO:0031836	neuromedin K receptor binding	molecular_function	Binding to a neuromedin K receptor.
GO:0031837	substance K receptor binding	molecular_function	Binding to a substance K receptor.
GO:0031838	haptoglobin-hemoglobin complex	cellular_component	A protein complex formed by the stable binding of a haptoglobin to hemoglobin.
GO:0031839	type 1 neuromedin U receptor binding	molecular_function	Binding to a type 1 neuromedin U receptor.
GO:0031840	type 2 neuromedin U receptor binding	molecular_function	Binding to a type 2 neuromedin U receptor.
GO:0031841	neuropeptide Y receptor binding	molecular_function	Binding to a neuropeptide Y receptor.
GO:0031842	type 1 neuropeptide Y receptor binding	molecular_function	Binding to a type 1 neuropeptide Y receptor.
GO:0031843	type 2 neuropeptide Y receptor binding	molecular_function	Binding to a type 2 neuropeptide Y receptor.
GO:0031844	type 4 neuropeptide Y receptor binding	molecular_function	Binding to a type 4 neuropeptide Y receptor.
GO:0031845	type 5 neuropeptide Y receptor binding	molecular_function	Binding to a type 5 neuropeptide Y receptor.
GO:0031846	neurotensin receptor binding	molecular_function	Binding to a neurotensin receptor.
GO:0031847	type 1 neurotensin receptor binding	molecular_function	Binding to a type 1 neurotensin receptor.
GO:0031848	protection from non-homologous end joining at telomere	biological_process	A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.
GO:0031849	olfactory receptor binding	molecular_function	Binding to an olfactory receptor.
GO:0031850	delta-type opioid receptor binding	molecular_function	Binding to a delta-type opioid receptor.
GO:0031851	kappa-type opioid receptor binding	molecular_function	Binding to a kappa-type opioid receptor.
GO:0031852	mu-type opioid receptor binding	molecular_function	Binding to a mu-type opioid receptor.
GO:0031853	nociceptin receptor binding	molecular_function	Binding to a nociceptin receptor.
GO:0031854	orexigenic neuropeptide QRFP receptor binding	molecular_function	Binding to an orexigenic neuropeptide QRFP receptor.
GO:0031855	oxytocin receptor binding	molecular_function	Binding to an oxytocin receptor.
GO:0031856	parathyroid hormone receptor binding	molecular_function	Binding to a parathyroid hormone receptor.
GO:0031857	type 1 parathyroid hormone receptor binding	molecular_function	Binding to a type 1 parathyroid hormone receptor.
GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding	molecular_function	Binding to a pituitary adenylate cyclase-activating polypeptide receptor.
GO:0031859	platelet activating factor receptor binding	molecular_function	Binding to a platelet activating factor receptor.
GO:0031860	telomeric 3' overhang formation	biological_process	The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.
GO:0031861	prolactin-releasing peptide receptor binding	molecular_function	Binding to a prolactin-releasing peptide receptor.
GO:0031862	prostanoid receptor binding	molecular_function	Binding to a prostanoid receptor.
GO:0031863	prostaglandin D2 receptor binding	molecular_function	Binding to a prostaglandin D2 receptor.
GO:0031864	EP1 subtype prostaglandin E2 receptor binding	molecular_function	Binding to an EP1 subtype prostaglandin E2 receptor.
GO:0031865	EP2 subtype prostaglandin E2 receptor binding	molecular_function	Binding to an EP2 subtype prostaglandin E2 receptor.
GO:0031866	EP3 subtype prostaglandin E2 receptor binding	molecular_function	Binding to an EP3 subtype prostaglandin E2 receptor.
GO:0031867	EP4 subtype prostaglandin E2 receptor binding	molecular_function	Binding to an EP4 subtype prostaglandin E2 receptor.
GO:0031868	prostaglandin F2-alpha receptor binding	molecular_function	Binding to a prostaglandin F2-alpha receptor.
GO:0031869	prostacyclin receptor binding	molecular_function	Binding to a prostacyclin receptor.
GO:0031870	thromboxane A2 receptor binding	molecular_function	Binding to a thromboxane A2 receptor.
GO:0031871	proteinase activated receptor binding	molecular_function	Binding to a proteinase activated receptor.
GO:0031872	type 1 proteinase activated receptor binding	molecular_function	Binding to a type 1 proteinase activated receptor.
GO:0031873	type 2 proteinase activated receptor binding	molecular_function	Binding to a type 2 proteinase activated receptor.
GO:0031874	type 3 proteinase activated receptor binding	molecular_function	Binding to a type 3 proteinase activated receptor.
GO:0031875	type 4 proteinase activated receptor binding	molecular_function	Binding to a type 4 proteinase activated receptor.
GO:0031876	secretin receptor binding	molecular_function	Binding to a secretin receptor.
GO:0031877	somatostatin receptor binding	molecular_function	Binding to a somatostatin receptor.
GO:0031878	type 1 somatostatin receptor binding	molecular_function	Binding to a type 1 somatostatin receptor.
GO:0031879	type 2 somatostatin receptor binding	molecular_function	Binding to a type 2 somatostatin receptor.
GO:0031880	type 3 somatostatin receptor binding	molecular_function	Binding to a type 3 somatostatin receptor.
GO:0031881	type 4 somatostatin receptor binding	molecular_function	Binding to a type 4 somatostatin receptor.
GO:0031882	type 5 somatostatin receptor binding	molecular_function	Binding to a type 5 somatostatin receptor.
GO:0031883	taste receptor binding	molecular_function	Binding to a taste receptor.
GO:0031884	type 1 member 1 taste receptor binding	molecular_function	Binding to a type 1 member 1 taste receptor.
GO:0031885	type 1 member 2 taste receptor binding	molecular_function	Binding to a type 1 member 2 taste receptor.
GO:0031886	type 1 member 3 taste receptor binding	molecular_function	Binding to a type 1 member 3 taste receptor.
GO:0031887	lipid droplet transport along microtubule	biological_process	The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.
GO:0031889	urotensin receptor binding	molecular_function	Binding to a urotensin receptor.
GO:0031890	vasoactive intestinal polypeptide receptor binding	molecular_function	Binding to a vasoactive intestinal polypeptide receptor.
GO:0031891	type 1 vasoactive intestinal polypeptide receptor binding	molecular_function	Binding to a type 1 vasoactive intestinal polypeptide receptor.
GO:0031892	type 2 vasoactive intestinal polypeptide receptor binding	molecular_function	Binding to a type 2 vasoactive intestinal polypeptide receptor.
GO:0031893	vasopressin receptor binding	molecular_function	Binding to a vasopressin receptor.
GO:0031894	V1A vasopressin receptor binding	molecular_function	Binding to a V1A vasopressin receptor.
GO:0031895	V1B vasopressin receptor binding	molecular_function	Binding to a V1B vasopressin receptor.
GO:0031896	V2 vasopressin receptor binding	molecular_function	Binding to a V2 vasopressin receptor.
GO:0031897	Tic complex	cellular_component	The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.
GO:0031898	chromoplast envelope	cellular_component	The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0031899	chromoplast inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.
GO:0031900	chromoplast outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.
GO:0031901	early endosome membrane	cellular_component	The lipid bilayer surrounding an early endosome.
GO:0031902	late endosome membrane	cellular_component	The lipid bilayer surrounding a late endosome.
GO:0031903	microbody membrane	cellular_component	The lipid bilayer surrounding a microbody.
GO:0031904	endosome lumen	cellular_component	The volume enclosed by the membrane of an endosome.
GO:0031905	early endosome lumen	cellular_component	The volume enclosed by the membrane of an early endosome.
GO:0031906	late endosome lumen	cellular_component	The volume enclosed by the membrane of a late endosome.
GO:0031907	microbody lumen	cellular_component	The volume enclosed by the membranes of a microbody.
GO:0031908	glyoxysomal lumen	cellular_component	The volume enclosed by the membranes of a glyoxysome.
GO:0031910	cytostome	cellular_component	Stable, specialized structure for the ingestion of food by the cell into phagosomes.
GO:0031911	cytoproct	cellular_component	Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.
GO:0031912	oral apparatus	cellular_component	Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.
GO:0031913	contractile vacuole pore	cellular_component	Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.
GO:0031914	negative regulation of synaptic plasticity	biological_process	A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
GO:0031915	positive regulation of synaptic plasticity	biological_process	A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
GO:0031916	regulation of synaptic metaplasticity	biological_process	A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
GO:0031917	negative regulation of synaptic metaplasticity	biological_process	A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
GO:0031918	positive regulation of synaptic metaplasticity	biological_process	A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
GO:0031919	vitamin B6 transport	biological_process	The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0031920	pyridoxal transport	biological_process	The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031921	pyridoxal phosphate transport	biological_process	The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
GO:0031922	pyridoxamine transport	biological_process	The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031923	pyridoxine transport	biological_process	The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031924	vitamin B6 transmembrane transporter activity	molecular_function	Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other.
GO:0031925	pyridoxal transmembrane transporter activity	molecular_function	Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031926	pyridoxal phosphate transmembrane transporter activity	molecular_function	Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
GO:0031927	pyridoxamine transmembrane transporter activity	molecular_function	Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031928	pyridoxine transmembrane transporter activity	molecular_function	Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0031929	TOR signaling	biological_process	The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.
GO:0031930	mitochondria-nucleus signaling pathway	biological_process	The series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.
GO:0031931	TORC1 complex	cellular_component	A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.
GO:0031932	TORC2 complex	cellular_component	A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
GO:0031934	mating-type region heterochromatin	cellular_component	Heterochromatic regions of the chromosome found at silenced mating-type loci.
GO:0031941	filamentous actin	cellular_component	A two-stranded helical polymer of the protein actin.
GO:0031942	i-AAA complex	cellular_component	Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.
GO:0031943	regulation of glucocorticoid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
GO:0031944	negative regulation of glucocorticoid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
GO:0031945	positive regulation of glucocorticoid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
GO:0031946	regulation of glucocorticoid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
GO:0031947	negative regulation of glucocorticoid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
GO:0031948	positive regulation of glucocorticoid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
GO:0031949	regulation of glucocorticoid catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
GO:0031950	negative regulation of glucocorticoid catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
GO:0031951	positive regulation of glucocorticoid catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
GO:0031952	regulation of protein autophosphorylation	biological_process	Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.
GO:0031953	negative regulation of protein autophosphorylation	biological_process	Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
GO:0031954	positive regulation of protein autophosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
GO:0031955	short-chain fatty acid-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0031956	medium-chain fatty acid-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0031957	very long-chain fatty acid-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
GO:0031958	corticosteroid receptor signaling pathway	biological_process	The series of molecular signals initiated by corticosteroid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0031959	mineralocorticoid receptor signaling pathway	biological_process	The series of molecular signals initiated by mineralocorticoid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0031960	response to corticosteroid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
GO:0031961	nuclear cortisol receptor binding	molecular_function	Binding to a nuclear cortisol receptor.
GO:0031962	nuclear mineralocorticoid receptor binding	molecular_function	Binding to a nuclear mineralocorticoid receptor.
GO:0031963	nuclear cortisol receptor activity	molecular_function	Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.
GO:0031964	beta-alanyl-histamine hydrolase activity	molecular_function	Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.
GO:0031965	nuclear membrane	cellular_component	Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
GO:0031966	mitochondrial membrane	cellular_component	Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
GO:0031967	organelle envelope	cellular_component	A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
GO:0031968	organelle outer membrane	cellular_component	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.
GO:0031969	chloroplast membrane	cellular_component	Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
GO:0031970	organelle envelope lumen	cellular_component	The region between the inner and outer lipid bilayers of an organelle envelope.
GO:0031972	chloroplast intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of a chloroplast envelope.
GO:0031973	chromoplast intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of a chromoplast envelope.
GO:0031974	membrane-enclosed lumen	cellular_component	The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GO:0031975	envelope	cellular_component	A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
GO:0031976	plastid thylakoid	cellular_component	Any thylakoid within a plastid.
GO:0031977	thylakoid lumen	cellular_component	The volume enclosed by a thylakoid membrane.
GO:0031978	plastid thylakoid lumen	cellular_component	The volume enclosed by a plastid thylakoid membrane.
GO:0031979	plasma membrane-derived thylakoid lumen	cellular_component	The volume enclosed by a plasma membrane-derived thylakoid.
GO:0031981	nuclear lumen	cellular_component	The volume enclosed by the nuclear inner membrane.
GO:0031982	vesicle	cellular_component	Any small, fluid-filled, spherical organelle enclosed by membrane.
GO:0031983	vesicle lumen	cellular_component	The volume enclosed by the membrane or protein that forms a vesicle.
GO:0031984	organelle subcompartment	cellular_component	A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
GO:0031985	Golgi cisterna	cellular_component	Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
GO:0031986	proteinoplast	cellular_component	A leucoplast in which protein is stored.
GO:0031987	locomotion involved in locomotory behavior	biological_process	Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GO:0031989	bombesin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a bombesin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0031990	mRNA export from nucleus in response to heat stress	biological_process	The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.
GO:0031991	regulation of actomyosin contractile ring contraction	biological_process	Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.
GO:0031992	energy transducer activity	molecular_function	The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.
GO:0031993	light transducer activity	molecular_function	Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.
GO:0031994	insulin-like growth factor I binding	molecular_function	Binding to insulin-like growth factor I.
GO:0031995	insulin-like growth factor II binding	molecular_function	Binding to insulin-like growth factor II.
GO:0031996	thioesterase binding	molecular_function	Binding to a thioesterase.
GO:0031998	regulation of fatty acid beta-oxidation	biological_process	Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.
GO:0031999	negative regulation of fatty acid beta-oxidation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.
GO:0032000	positive regulation of fatty acid beta-oxidation	biological_process	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.
GO:0032001	1,4-alpha-glucan 6-alpha-glucosyltransferase activity	molecular_function	Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.
GO:0032002	interleukin-28 receptor complex	cellular_component	A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).
GO:0032003	interleukin-28 receptor binding	molecular_function	Binding to an interleukin-28 receptor.
GO:0032005	signal transduction involved in positive regulation of conjugation with cellular fusion	biological_process	The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
GO:0032006	regulation of TOR signaling	biological_process	Any process that modulates the frequency, rate or extent of TOR signaling.
GO:0032007	negative regulation of TOR signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
GO:0032008	positive regulation of TOR signaling	biological_process	Any process that activates or increases the frequency, rate or extent of TOR signaling.
GO:0032009	early phagosome	cellular_component	A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.
GO:0032010	phagolysosome	cellular_component	A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.
GO:0032011	ARF protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.
GO:0032012	regulation of ARF protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of ARF protein signal transduction.
GO:0032013	negative regulation of ARF protein signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.
GO:0032014	positive regulation of ARF protein signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.
GO:0032015	regulation of Ran protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Ran protein signal transduction.
GO:0032016	negative regulation of Ran protein signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction.
GO:0032017	positive regulation of Ran protein signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction.
GO:0032018	2-methylbutanol:NADP oxidoreductase activity	molecular_function	Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.
GO:0032019	mitochondrial cloud	cellular_component	A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
GO:0032020	ISG15-protein conjugation	biological_process	The covalent addition to a protein of ISG15, a ubiquitin-like protein.
GO:0032021	NELF complex	cellular_component	A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.
GO:0032023	trypsinogen activation	biological_process	The proteolytic processing of trypsinogen to the active form, trypsin.
GO:0032024	positive regulation of insulin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
GO:0032025	response to cobalt ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
GO:0032026	response to magnesium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
GO:0032027	myosin light chain binding	molecular_function	Binding to a light chain of a myosin complex.
GO:0032028	myosin head/neck binding	molecular_function	Binding to the head/neck region of a myosin heavy chain.
GO:0032029	myosin tail binding	molecular_function	Binding to the tail region of a myosin heavy chain.
GO:0032030	myosin I light chain binding	molecular_function	Binding to a light chain of a myosin I complex.
GO:0032031	myosin I head/neck binding	molecular_function	Binding to the head/neck region of a myosin I heavy chain.
GO:0032032	myosin I tail binding	molecular_function	Binding to the tail region of a myosin I heavy chain.
GO:0032033	myosin II light chain binding	molecular_function	Binding to a light chain of a myosin II complex.
GO:0032034	myosin II head/neck binding	molecular_function	Binding to the head/neck region of a myosin II heavy chain.
GO:0032035	myosin II tail binding	molecular_function	Binding to the tail region of a myosin II heavy chain.
GO:0032036	myosin heavy chain binding	molecular_function	Binding to a heavy chain of a myosin complex.
GO:0032037	myosin I heavy chain binding	molecular_function	Binding to a heavy chain of a myosin I complex.
GO:0032038	myosin II heavy chain binding	molecular_function	Binding to a heavy chain of a myosin II complex.
GO:0032039	integrator complex	cellular_component	A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
GO:0032040	small-subunit processome	cellular_component	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
GO:0032041	NAD-dependent histone H3K14 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
GO:0032042	mitochondrial DNA metabolic process	biological_process	The chemical reactions and pathways involving mitochondrial DNA.
GO:0032043	mitochondrial DNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.
GO:0032044	DSIF complex	cellular_component	A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.
GO:0032045	guanyl-nucleotide exchange factor complex	cellular_component	A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.
GO:0032046	micropexophagy-specific membrane apparatus	cellular_component	A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.
GO:0032047	mitosome	cellular_component	A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.
GO:0032048	cardiolipin metabolic process	biological_process	The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
GO:0032049	cardiolipin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
GO:0032050	clathrin heavy chain binding	molecular_function	Binding to a clathrin heavy chain.
GO:0032051	clathrin light chain binding	molecular_function	Binding to a clathrin light chain.
GO:0032052	bile acid binding	molecular_function	Binding to a bile acid, a steroid carboxylic acids occurring in bile.
GO:0032053	ciliary basal body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).
GO:0032055	negative regulation of translation in response to stress	biological_process	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.
GO:0032056	positive regulation of translation in response to stress	biological_process	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.
GO:0032057	negative regulation of translational initiation in response to stress	biological_process	Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.
GO:0032058	positive regulation of translational initiation in response to stress	biological_process	Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.
GO:0032059	bleb	cellular_component	A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
GO:0032060	bleb assembly	biological_process	The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
GO:0032061	negative regulation of translation in response to osmotic stress	biological_process	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0032062	positive regulation of translation in response to osmotic stress	biological_process	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0032063	negative regulation of translational initiation in response to osmotic stress	biological_process	Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0032064	positive regulation of translational initiation in response to osmotic stress	biological_process	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0032065	maintenance of protein location in cell cortex	biological_process	A process in which a protein or protein complex is maintained in a specific location in the cell cortex.
GO:0032067	type IV site-specific deoxyribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).
GO:0032068	type IV site-specific deoxyribonuclease complex	cellular_component	A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.
GO:0032069	regulation of nuclease activity	biological_process	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GO:0032070	regulation of deoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0032071	regulation of endodeoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0032072	regulation of restriction endodeoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
GO:0032073	negative regulation of restriction endodeoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
GO:0032074	negative regulation of nuclease activity	biological_process	Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GO:0032075	positive regulation of nuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GO:0032076	negative regulation of deoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0032077	positive regulation of deoxyribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0032078	negative regulation of endodeoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0032079	positive regulation of endodeoxyribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
GO:0032080	negative regulation of type I site-specific deoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.
GO:0032081	negative regulation of type II site-specific deoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.
GO:0032082	negative regulation of type III site-specific deoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.
GO:0032083	negative regulation of type IV site-specific deoxyribonuclease activity	biological_process	Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.
GO:0032084	regulation of type I site-specific deoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.
GO:0032085	regulation of type II site-specific deoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity.
GO:0032086	regulation of type III site-specific deoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.
GO:0032087	regulation of type IV site-specific deoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.
GO:0032088	negative regulation of NF-kappaB transcription factor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
GO:0032089	NACHT domain binding	molecular_function	Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg2+-binding site and five more specific motifs.
GO:0032090	Pyrin domain binding	molecular_function	Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.
GO:0032091	negative regulation of protein binding	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
GO:0032092	positive regulation of protein binding	biological_process	Any process that activates or increases the frequency, rate or extent of protein binding.
GO:0032093	SAM domain binding	molecular_function	Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.
GO:0032094	response to food	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
GO:0032095	regulation of response to food	biological_process	Any process that modulates the frequency, rate or extent of a response to a food stimulus.
GO:0032096	negative regulation of response to food	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.
GO:0032097	positive regulation of response to food	biological_process	Any process that activates, maintains, or increases the rate of a response to a food stimulus.
GO:0032098	regulation of appetite	biological_process	Any process which modulates appetite, the desire or physical craving for food.
GO:0032099	negative regulation of appetite	biological_process	Any process that reduces appetite.
GO:0032100	positive regulation of appetite	biological_process	Any process that increases appetite.
GO:0032101	regulation of response to external stimulus	biological_process	Any process that modulates the frequency, rate or extent of a response to an external stimulus.
GO:0032102	negative regulation of response to external stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
GO:0032103	positive regulation of response to external stimulus	biological_process	Any process that activates, maintains or increases the rate of a response to an external stimulus.
GO:0032104	regulation of response to extracellular stimulus	biological_process	Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.
GO:0032105	negative regulation of response to extracellular stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.
GO:0032106	positive regulation of response to extracellular stimulus	biological_process	Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.
GO:0032107	regulation of response to nutrient levels	biological_process	Any process that modulates the frequency, rate or extent of a response to nutrient levels.
GO:0032108	negative regulation of response to nutrient levels	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.
GO:0032109	positive regulation of response to nutrient levels	biological_process	Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.
GO:0032110	regulation of protein histidine kinase activity	biological_process	Any process that modulates the frequency, rate or extent of protein histidine kinase activity.
GO:0032112	negative regulation of protein histidine kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.
GO:0032113	regulation of carbohydrate phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.
GO:0032114	regulation of glucose-6-phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.
GO:0032115	sorbose reductase activity	molecular_function	Catalysis of the reaction: D-glucitol + NADP+ = L-sorbose + H+ + NADPH. The reaction may occur, to a minor extent, in the reverse direction.
GO:0032116	SMC loading complex	cellular_component	A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.
GO:0032117	horsetail-astral microtubule array	cellular_component	An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.
GO:0032118	horsetail-astral microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.
GO:0032119	sequestering of zinc ion	biological_process	The process of binding or confining zinc ions such that they are separated from other components of a biological system.
GO:0032120	ascospore-type prospore membrane formation	biological_process	The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
GO:0032121	meiotic attachment of telomeric heterochromatin to spindle pole body	biological_process	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.
GO:0032122	oral apparatus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.
GO:0032123	deep fiber	cellular_component	Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.
GO:0032124	macronucleus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.
GO:0032125	micronucleus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.
GO:0032126	eisosome	cellular_component	A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.
GO:0032127	dense core granule membrane	cellular_component	The lipid bilayer surrounding a dense core granule.
GO:0032129	histone H3K9 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
GO:0032130	medial membrane band assembly	biological_process	The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.
GO:0032131	alkylated DNA binding	molecular_function	Binding to an alkylated residue in DNA.
GO:0032132	O6-alkylguanine-DNA binding	molecular_function	Binding to an O6-alkylguanine adduct in DNA.
GO:0032133	chromosome passenger complex	cellular_component	A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.
GO:0032135	DNA insertion or deletion binding	molecular_function	Binding to a double-stranded DNA region containing an insertion or a deletion.
GO:0032136	adenine/cytosine mispair binding	molecular_function	Binding to a double-stranded DNA region containing an A/C mispair.
GO:0032137	guanine/thymine mispair binding	molecular_function	Binding to a double-stranded DNA region containing a G/T mispair.
GO:0032138	single base insertion or deletion binding	molecular_function	Binding to a double-stranded DNA region containing a single base insertion or deletion.
GO:0032139	dinucleotide insertion or deletion binding	molecular_function	Binding to a double-stranded DNA region containing a dinucleotide insertion or deletion.
GO:0032140	single adenine insertion binding	molecular_function	Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine.
GO:0032141	single cytosine insertion binding	molecular_function	Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine.
GO:0032142	single guanine insertion binding	molecular_function	Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine.
GO:0032143	single thymine insertion binding	molecular_function	Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine.
GO:0032144	4-aminobutyrate transaminase complex	cellular_component	A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity.
GO:0032145	succinate-semialdehyde dehydrogenase binding	molecular_function	Binding to succinate-semialdehyde dehydrogenase.
GO:0032147	activation of protein kinase activity	biological_process	Any process that initiates the activity of an inactive protein kinase.
GO:0032148	activation of protein kinase B activity	biological_process	Any process that initiates the activity of the inactive enzyme protein kinase B.
GO:0032149	response to rhamnose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.
GO:0032150	ubiquinone biosynthetic process from chorismate	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.
GO:0032151	mitotic septin complex	cellular_component	A heterooligomeric septin complex that acts during mitotic cell division.
GO:0032152	meiotic septin complex	cellular_component	A heterooligomeric septin complex that acts during meiotic cell division.
GO:0032153	cell division site	cellular_component	The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
GO:0032154	cleavage furrow	cellular_component	The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
GO:0032156	septin cytoskeleton	cellular_component	The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.
GO:0032157	prospore contractile ring	cellular_component	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.
GO:0032158	septin band	cellular_component	A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
GO:0032159	septin cap	cellular_component	A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
GO:0032160	septin filament array	cellular_component	Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.
GO:0032161	cleavage apparatus septin structure	cellular_component	Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.
GO:0032162	mating projection septin band	cellular_component	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).
GO:0032163	hyphal septin band	cellular_component	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
GO:0032164	hyphal septin cap	cellular_component	A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
GO:0032165	prospore septin filament array	cellular_component	Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.
GO:0032166	chlamydospore septin filament array	cellular_component	Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.
GO:0032168	hyphal septin ring	cellular_component	A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
GO:0032169	prospore septin ring	cellular_component	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.
GO:0032170	pseudohyphal septin ring	cellular_component	A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.
GO:0032171	germ tube septin cap	cellular_component	A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
GO:0032172	germ tube septin ring	cellular_component	A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
GO:0032173	septin collar	cellular_component	A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.
GO:0032174	cellular bud neck septin collar	cellular_component	A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.
GO:0032175	mating projection septin ring	cellular_component	A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.
GO:0032176	split septin rings	cellular_component	A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.
GO:0032177	cellular bud neck split septin rings	cellular_component	Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.
GO:0032178	medial membrane band	cellular_component	A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.
GO:0032179	germ tube	cellular_component	The slender tubular outgrowth first produced by most spores in germination.
GO:0032180	ubiquinone biosynthetic process from tyrosine	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.
GO:0032181	dinucleotide repeat insertion binding	molecular_function	Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.
GO:0032182	ubiquitin-like protein binding	molecular_function	Binding to a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
GO:0032183	SUMO binding	molecular_function	Binding to the small ubiquitin-like protein SUMO.
GO:0032184	SUMO polymer binding	molecular_function	Binding to a polymer of the small ubiquitin-like protein SUMO.
GO:0032185	septin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.
GO:0032186	cellular bud neck septin ring organization	biological_process	Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.
GO:0032190	acrosin binding	molecular_function	Binding to acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
GO:0032193	ubiquinone biosynthetic process via 2-polyprenylphenol	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.
GO:0032194	ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.
GO:0032195	post-lysosomal vacuole	cellular_component	A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.
GO:0032196	transposition	biological_process	Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site.
GO:0032197	retrotransposition	biological_process	A type of transposition in which a transposable element (transposon) copies and pastes itself into a different genomic location by transcription and convertsion of the transcribed RNA back into DNA through reverse transcription.
GO:0032200	telomere organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.
GO:0032201	telomere maintenance via semi-conservative replication	biological_process	The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.
GO:0032202	telomere assembly	biological_process	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.
GO:0032203	telomere formation via telomerase	biological_process	A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.
GO:0032204	regulation of telomere maintenance	biological_process	Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
GO:0032205	negative regulation of telomere maintenance	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
GO:0032206	positive regulation of telomere maintenance	biological_process	Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
GO:0032207	regulation of telomere maintenance via recombination	biological_process	Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
GO:0032208	negative regulation of telomere maintenance via recombination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
GO:0032209	positive regulation of telomere maintenance via recombination	biological_process	Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
GO:0032210	regulation of telomere maintenance via telomerase	biological_process	Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
GO:0032211	negative regulation of telomere maintenance via telomerase	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
GO:0032212	positive regulation of telomere maintenance via telomerase	biological_process	Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
GO:0032213	regulation of telomere maintenance via semi-conservative replication	biological_process	Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
GO:0032215	positive regulation of telomere maintenance via semi-conservative replication	biological_process	Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
GO:0032216	glucosaminyl-phosphatidylinositol O-acyltransferase activity	molecular_function	Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA.
GO:0032217	riboflavin transmembrane transporter activity	molecular_function	Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
GO:0032218	riboflavin transport	biological_process	The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
GO:0032219	cell wall macromolecule catabolic process involved in cytogamy	biological_process	The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.
GO:0032220	plasma membrane fusion involved in cytogamy	biological_process	The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.
GO:0032221	Rpd3S complex	cellular_component	A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).
GO:0032222	regulation of synaptic transmission, cholinergic	biological_process	Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
GO:0032223	negative regulation of synaptic transmission, cholinergic	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
GO:0032224	positive regulation of synaptic transmission, cholinergic	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
GO:0032225	regulation of synaptic transmission, dopaminergic	biological_process	Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
GO:0032226	positive regulation of synaptic transmission, dopaminergic	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
GO:0032227	negative regulation of synaptic transmission, dopaminergic	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
GO:0032228	regulation of synaptic transmission, GABAergic	biological_process	Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
GO:0032229	negative regulation of synaptic transmission, GABAergic	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
GO:0032230	positive regulation of synaptic transmission, GABAergic	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
GO:0032231	regulation of actin filament bundle assembly	biological_process	Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.
GO:0032232	negative regulation of actin filament bundle assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.
GO:0032233	positive regulation of actin filament bundle assembly	biological_process	Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.
GO:0032237	activation of store-operated calcium channel activity	biological_process	A process that initiates the activity of an inactive store-operated calcium channel.
GO:0032238	adenosine transport	biological_process	The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032239	regulation of nucleobase-containing compound transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032240	negative regulation of nucleobase-containing compound transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032241	positive regulation of nucleobase-containing compound transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032242	regulation of nucleoside transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032243	negative regulation of nucleoside transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032244	positive regulation of nucleoside transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032245	regulation of purine nucleoside transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032246	regulation of pyrimidine nucleoside transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032247	negative regulation of purine nucleoside transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032248	positive regulation of purine nucleoside transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032249	regulation of adenosine transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032250	negative regulation of adenosine transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032251	positive regulation of adenosine transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032252	secretory granule localization	biological_process	Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.
GO:0032253	dense core granule localization	biological_process	Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.
GO:0032254	establishment of secretory granule localization	biological_process	The directed movement of a secretory granule to a specific location.
GO:0032255	maintenance of secretory granule location	biological_process	Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0032256	establishment of dense core granule localization	biological_process	The directed movement of a dense core granule to a specific location.
GO:0032257	maintenance of dense core granule location	biological_process	Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0032258	cytoplasm to vacuole transport by the Cvt pathway	biological_process	A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
GO:0032259	methylation	biological_process	The process in which a methyl group is covalently attached to a molecule.
GO:0032260	response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
GO:0032261	purine nucleotide salvage	biological_process	Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
GO:0032262	pyrimidine nucleotide salvage	biological_process	Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.
GO:0032263	GMP salvage	biological_process	Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
GO:0032264	IMP salvage	biological_process	Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.
GO:0032265	XMP salvage	biological_process	Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.
GO:0032266	phosphatidylinositol-3-phosphate binding	molecular_function	Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.
GO:0032267	tRNA(Ile)-lysidine synthase activity	molecular_function	Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.
GO:0032271	regulation of protein polymerization	biological_process	Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
GO:0032272	negative regulation of protein polymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
GO:0032273	positive regulation of protein polymerization	biological_process	Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
GO:0032274	gonadotropin secretion	biological_process	The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.
GO:0032275	luteinizing hormone secretion	biological_process	The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
GO:0032276	regulation of gonadotropin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.
GO:0032277	negative regulation of gonadotropin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.
GO:0032278	positive regulation of gonadotropin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.
GO:0032279	asymmetric synapse	cellular_component	A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.
GO:0032280	symmetric synapse	cellular_component	A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory.
GO:0032281	AMPA glutamate receptor complex	cellular_component	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
GO:0032282	plastid acetyl-CoA carboxylase complex	cellular_component	An acetyl-CoA carboxylase complex located in the stroma of a plastid.
GO:0032283	plastid acetate CoA-transferase complex	cellular_component	An acetate CoA-transferase complex located in the stroma of a plastid.
GO:0032285	non-myelinated axon ensheathment	biological_process	The process in which a non-myelinating glial cell membrane closes around an axon.
GO:0032286	central nervous system myelin maintenance	biological_process	The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
GO:0032287	peripheral nervous system myelin maintenance	biological_process	The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
GO:0032288	myelin assembly	biological_process	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
GO:0032289	central nervous system myelin formation	biological_process	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
GO:0032290	peripheral nervous system myelin formation	biological_process	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.
GO:0032291	axon ensheathment in central nervous system	biological_process	The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.
GO:0032292	peripheral nervous system axon ensheathment	biological_process	The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.
GO:0032293	non-myelinated axon ensheathment in central nervous system	biological_process	The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.
GO:0032294	peripheral nervous system non-myelinated axon ensheathment	biological_process	The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.
GO:0032295	ensheathment of neuronal cell bodies	biological_process	The process in which satellite glial cells isolate neuronal cell bodies.
GO:0032296	double-stranded RNA-specific ribonuclease activity	molecular_function	Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.
GO:0032297	negative regulation of DNA-templated DNA replication initiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
GO:0032298	positive regulation of DNA-templated DNA replication initiation	biological_process	Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.
GO:0032299	ribonuclease H2 complex	cellular_component	A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.
GO:0032300	mismatch repair complex	cellular_component	Any complex formed of proteins that act in mismatch repair.
GO:0032301	MutSalpha complex	cellular_component	A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
GO:0032302	MutSbeta complex	cellular_component	A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.
GO:0032303	regulation of icosanoid secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.
GO:0032304	negative regulation of icosanoid secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.
GO:0032305	positive regulation of icosanoid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.
GO:0032306	regulation of prostaglandin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
GO:0032307	negative regulation of prostaglandin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
GO:0032308	positive regulation of prostaglandin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
GO:0032309	icosanoid secretion	biological_process	The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.
GO:0032310	prostaglandin secretion	biological_process	The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
GO:0032311	angiogenin-PRI complex	cellular_component	A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.
GO:0032322	ubiquinone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.
GO:0032323	lipoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipoate.
GO:0032324	molybdopterin cofactor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
GO:0032325	molybdopterin cofactor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
GO:0032326	Mo-molybdopterin cofactor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
GO:0032327	W-molybdopterin cofactor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
GO:0032328	alanine transport	biological_process	The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032329	serine transport	biological_process	The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032330	regulation of chondrocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
GO:0032331	negative regulation of chondrocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
GO:0032332	positive regulation of chondrocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
GO:0032333	activin secretion	biological_process	The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
GO:0032334	inhibin secretion	biological_process	The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
GO:0032335	regulation of activin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.
GO:0032336	negative regulation of activin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.
GO:0032337	positive regulation of activin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.
GO:0032338	regulation of inhibin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.
GO:0032339	negative regulation of inhibin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.
GO:0032340	positive regulation of inhibin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.
GO:0032341	aldosterone metabolic process	biological_process	The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
GO:0032342	aldosterone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
GO:0032343	aldosterone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
GO:0032344	regulation of aldosterone metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
GO:0032345	negative regulation of aldosterone metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
GO:0032346	positive regulation of aldosterone metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
GO:0032347	regulation of aldosterone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
GO:0032348	negative regulation of aldosterone biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
GO:0032349	positive regulation of aldosterone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
GO:0032350	regulation of hormone metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
GO:0032351	negative regulation of hormone metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
GO:0032352	positive regulation of hormone metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
GO:0032353	negative regulation of hormone biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
GO:0032354	response to follicle-stimulating hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
GO:0032355	response to estradiol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
GO:0032356	oxidized DNA binding	molecular_function	Binding to a DNA region containing an oxidized residue.
GO:0032357	oxidized purine DNA binding	molecular_function	Binding to a DNA region containing an oxidized purine residue.
GO:0032358	oxidized pyrimidine DNA binding	molecular_function	Binding to a DNA region containing an oxidized pyrimidine residue.
GO:0032359	provirus excision	biological_process	The molecular events that lead to the excision of a viral genome from the host genome.
GO:0032361	pyridoxal phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
GO:0032363	FMN catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
GO:0032364	intracellular oxygen homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.
GO:0032365	intracellular lipid transport	biological_process	The directed movement of lipids within cells.
GO:0032366	intracellular sterol transport	biological_process	The directed movement of sterols within cells.
GO:0032367	intracellular cholesterol transport	biological_process	The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
GO:0032368	regulation of lipid transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032369	negative regulation of lipid transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032370	positive regulation of lipid transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032371	regulation of sterol transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032372	negative regulation of sterol transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032373	positive regulation of sterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032374	regulation of cholesterol transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032375	negative regulation of cholesterol transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032376	positive regulation of cholesterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032377	regulation of intracellular lipid transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
GO:0032378	negative regulation of intracellular lipid transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
GO:0032379	positive regulation of intracellular lipid transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
GO:0032380	regulation of intracellular sterol transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.
GO:0032381	negative regulation of intracellular sterol transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.
GO:0032382	positive regulation of intracellular sterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.
GO:0032383	regulation of intracellular cholesterol transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
GO:0032384	negative regulation of intracellular cholesterol transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.
GO:0032385	positive regulation of intracellular cholesterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.
GO:0032386	regulation of intracellular transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
GO:0032387	negative regulation of intracellular transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
GO:0032388	positive regulation of intracellular transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
GO:0032389	MutLalpha complex	cellular_component	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
GO:0032390	MutLbeta complex	cellular_component	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.
GO:0032391	photoreceptor connecting cilium	cellular_component	The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
GO:0032392	DNA geometric change	biological_process	The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
GO:0032393	MHC class I receptor activity	molecular_function	Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
GO:0032394	MHC class Ib receptor activity	molecular_function	Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
GO:0032395	MHC class II receptor activity	molecular_function	Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0032396	inhibitory MHC class I receptor activity	molecular_function	Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.
GO:0032397	activating MHC class I receptor activity	molecular_function	Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
GO:0032398	MHC class Ib protein complex	cellular_component	A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
GO:0032399	HECT domain binding	molecular_function	Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein.
GO:0032400	melanosome localization	biological_process	Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.
GO:0032401	establishment of melanosome localization	biological_process	The directed movement of a melanosome to a specific location.
GO:0032402	melanosome transport	biological_process	The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032404	mismatch repair complex binding	molecular_function	Binding to a mismatch repair complex.
GO:0032405	MutLalpha complex binding	molecular_function	Binding to a MutLalpha mismatch repair complex.
GO:0032406	MutLbeta complex binding	molecular_function	Binding to a MutLbeta mismatch repair complex.
GO:0032407	MutSalpha complex binding	molecular_function	Binding to a MutSalpha mismatch repair complex.
GO:0032408	MutSbeta complex binding	molecular_function	Binding to a MutSbeta mismatch repair complex.
GO:0032409	regulation of transporter activity	biological_process	Any process that modulates the activity of a transporter.
GO:0032410	negative regulation of transporter activity	biological_process	Any process that stops or reduces the activity of a transporter.
GO:0032411	positive regulation of transporter activity	biological_process	Any process that activates or increases the activity of a transporter.
GO:0032412	regulation of monoatomic ion transmembrane transporter activity	biological_process	Any process that modulates the activity of an ion transporter.
GO:0032413	negative regulation of ion transmembrane transporter activity	biological_process	Any process that stops or reduces the activity of an ion transporter.
GO:0032414	positive regulation of ion transmembrane transporter activity	biological_process	Any process that activates or increases the activity of an ion transporter.
GO:0032415	regulation of sodium:proton antiporter activity	biological_process	Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
GO:0032416	negative regulation of sodium:proton antiporter activity	biological_process	Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
GO:0032417	positive regulation of sodium:proton antiporter activity	biological_process	Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
GO:0032418	lysosome localization	biological_process	Any process in which a lysosome is transported to, and/or maintained in, a specific location.
GO:0032420	stereocilium	cellular_component	An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
GO:0032421	stereocilium bundle	cellular_component	A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.
GO:0032422	purine-rich negative regulatory element binding	molecular_function	Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
GO:0032423	regulation of mismatch repair	biological_process	Any process that modulates the frequency, rate or extent of mismatch repair.
GO:0032424	negative regulation of mismatch repair	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.
GO:0032425	positive regulation of mismatch repair	biological_process	Any process that activates or increases the frequency, rate or extent of mismatch repair.
GO:0032426	stereocilium tip	cellular_component	A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.
GO:0032427	GBD domain binding	molecular_function	Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.
GO:0032428	beta-N-acetylgalactosaminidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.
GO:0032429	regulation of phospholipase A2 activity	biological_process	Any process that modulates the activity of the enzyme phospholipase A2.
GO:0032430	positive regulation of phospholipase A2 activity	biological_process	Any process that activates or increases the activity of the enzyme phospholipase A2.
GO:0032431	activation of phospholipase A2 activity	biological_process	Any process that initiates the activity of the inactive enzyme phospholipase A2.
GO:0032432	actin filament bundle	cellular_component	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
GO:0032433	filopodium tip	cellular_component	The end of a filopodium distal to the body of the cell.
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0032437	cuticular plate	cellular_component	A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
GO:0032438	melanosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
GO:0032440	2-alkenal reductase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.
GO:0032441	pheophorbide a oxygenase activity	molecular_function	Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.
GO:0032442	phenylcoumaran benzylic ether reductase activity	molecular_function	Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.
GO:0032443	regulation of ergosterol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
GO:0032444	activin responsive factor complex	cellular_component	A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.
GO:0032446	protein modification by small protein conjugation	biological_process	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
GO:0032447	protein urmylation	biological_process	Covalent attachment of the ubiquitin-like protein URM1 to another protein.
GO:0032448	DNA hairpin binding	molecular_function	Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.
GO:0032449	CBM complex	cellular_component	A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation.
GO:0032450	maltose alpha-glucosidase activity	molecular_function	Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.
GO:0032451	demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a substrate.
GO:0032452	histone demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a histone.
GO:0032453	histone H3K4 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein.
GO:0032454	histone H3K9 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.
GO:0032455	nerve growth factor processing	biological_process	The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.
GO:0032456	endocytic recycling	biological_process	The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
GO:0032457	fast endocytic recycling	biological_process	The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
GO:0032458	slow endocytic recycling	biological_process	The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
GO:0032459	regulation of protein oligomerization	biological_process	Any process that modulates the frequency, rate or extent of protein oligomerization.
GO:0032460	negative regulation of protein oligomerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.
GO:0032461	positive regulation of protein oligomerization	biological_process	Any process that activates or increases the frequency, rate or extent of protein oligomerization.
GO:0032462	regulation of protein homooligomerization	biological_process	Any process that modulates the frequency, rate or extent of protein homooligomerization.
GO:0032463	negative regulation of protein homooligomerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.
GO:0032464	positive regulation of protein homooligomerization	biological_process	Any process that activates or increases the frequency, rate or extent of protein homooligomerization.
GO:0032465	regulation of cytokinesis	biological_process	Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
GO:0032466	negative regulation of cytokinesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
GO:0032467	positive regulation of cytokinesis	biological_process	Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
GO:0032468	Golgi calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
GO:0032469	endoplasmic reticulum calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration	biological_process	Any process that increases the concentration of calcium ions in the endoplasmic reticulum.
GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	biological_process	Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.
GO:0032472	Golgi calcium ion transport	biological_process	The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.
GO:0032473	cytoplasmic side of mitochondrial outer membrane	cellular_component	The external (cytoplasmic) face of the mitochondrial outer membrane.
GO:0032474	otolith morphogenesis	biological_process	The process in which the anatomical structures of an otolith are generated and organized.
GO:0032475	otolith formation	biological_process	The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.
GO:0032476	decaprenyl diphosphate synthase complex	cellular_component	A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.
GO:0032477	homodimeric decaprenyl diphosphate synthase complex	cellular_component	A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.
GO:0032478	heterotetrameric decaprenyl diphosphate synthase complex	cellular_component	A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.
GO:0032479	regulation of type I interferon production	biological_process	Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0032480	negative regulation of type I interferon production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0032481	positive regulation of type I interferon production	biological_process	Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0032482	Rab protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
GO:0032483	regulation of Rab protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
GO:0032484	Ral protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.
GO:0032485	regulation of Ral protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
GO:0032486	Rap protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
GO:0032487	regulation of Rap protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Rap protein signal transduction.
GO:0032488	Cdc42 protein signal transduction	biological_process	The series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.
GO:0032489	regulation of Cdc42 protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.
GO:0032490	detection of molecule of bacterial origin	biological_process	The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.
GO:0032491	detection of molecule of fungal origin	biological_process	The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.
GO:0032492	detection of molecule of oomycetes origin	biological_process	The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.
GO:0032493	response to bacterial lipoprotein	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.
GO:0032494	response to peptidoglycan	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
GO:0032495	response to muramyl dipeptide	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
GO:0032496	response to lipopolysaccharide	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
GO:0032497	detection of lipopolysaccharide	biological_process	The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
GO:0032498	detection of muramyl dipeptide	biological_process	The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.
GO:0032499	detection of peptidoglycan	biological_process	The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.
GO:0032500	muramyl dipeptide binding	molecular_function	Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.
GO:0032501	multicellular organismal process	biological_process	Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0032502	developmental process	biological_process	A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0032504	multicellular organism reproduction	biological_process	The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GO:0032505	reproduction of a single-celled organism	biological_process	The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GO:0032506	cytokinetic process	biological_process	A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
GO:0032507	maintenance of protein location in cell	biological_process	Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
GO:0032508	DNA duplex unwinding	biological_process	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
GO:0032509	endosome transport via multivesicular body sorting pathway	biological_process	The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	biological_process	The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	biological_process	The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.
GO:0032515	negative regulation of phosphoprotein phosphatase activity	biological_process	Any process that stops or reduces the activity of a phosphoprotein phosphatase.
GO:0032516	positive regulation of phosphoprotein phosphatase activity	biological_process	Any process that activates or increases the activity of a phosphoprotein phosphatase.
GO:0032517	SOD1-calcineurin complex	cellular_component	A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.
GO:0032523	silicon efflux transmembrane transporter activity	molecular_function	Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.
GO:0032525	somite rostral/caudal axis specification	biological_process	The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.
GO:0032526	response to retinoic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
GO:0032527	protein exit from endoplasmic reticulum	biological_process	The directed movement of proteins from the endoplasmic reticulum.
GO:0032528	microvillus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
GO:0032529	follicle cell microvillus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.
GO:0032530	regulation of microvillus organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.
GO:0032531	regulation of follicle cell microvillus organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.
GO:0032532	regulation of microvillus length	biological_process	A process that modulates the length of a microvillus.
GO:0032533	regulation of follicle cell microvillus length	biological_process	A process that modulates the length of a microvillus on a follicle cell.
GO:0032534	regulation of microvillus assembly	biological_process	A process that modulates the formation of a microvillus.
GO:0032535	regulation of cellular component size	biological_process	A process that modulates the size of a cellular component.
GO:0032536	regulation of cell projection size	biological_process	A process that modulates the size of a cell projection.
GO:0032537	host-seeking behavior	biological_process	The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.
GO:0032538	regulation of host-seeking behavior	biological_process	Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.
GO:0032539	negative regulation of host-seeking behavior	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.
GO:0032540	positive regulation of host-seeking behavior	biological_process	Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.
GO:0032541	cortical endoplasmic reticulum	cellular_component	A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
GO:0032542	sulfiredoxin activity	molecular_function	Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.
GO:0032543	mitochondrial translation	biological_process	The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
GO:0032544	plastid translation	biological_process	The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
GO:0032545	CURI complex	cellular_component	A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.
GO:0032546	deoxyribonucleoside binding	molecular_function	Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.
GO:0032547	purine deoxyribonucleoside binding	molecular_function	Binding to a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
GO:0032548	pyrimidine deoxyribonucleoside binding	molecular_function	Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
GO:0032549	ribonucleoside binding	molecular_function	Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
GO:0032550	purine ribonucleoside binding	molecular_function	Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.
GO:0032551	pyrimidine ribonucleoside binding	molecular_function	Binding to a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.
GO:0032552	deoxyribonucleotide binding	molecular_function	Binding to a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
GO:0032553	ribonucleotide binding	molecular_function	Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032554	purine deoxyribonucleotide binding	molecular_function	Binding to a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
GO:0032555	purine ribonucleotide binding	molecular_function	Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032556	pyrimidine deoxyribonucleotide binding	molecular_function	Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
GO:0032557	pyrimidine ribonucleotide binding	molecular_function	Binding to a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032558	adenyl deoxyribonucleotide binding	molecular_function	Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
GO:0032559	adenyl ribonucleotide binding	molecular_function	Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032560	guanyl deoxyribonucleotide binding	molecular_function	Binding to a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
GO:0032561	guanyl ribonucleotide binding	molecular_function	Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032562	dAMP binding	molecular_function	Binding to dAMP, deoxyadenosine monophosphate.
GO:0032563	dADP binding	molecular_function	Binding to dADP, deoxyadenosine diphosphate.
GO:0032564	dATP binding	molecular_function	Binding to dATP, deoxyadenosine triphosphate.
GO:0032565	dGMP binding	molecular_function	Binding to dGMP, deoxyguanosine monophosphate.
GO:0032566	dGDP binding	molecular_function	Binding to dGDP, deoxyguanosine diphosphate.
GO:0032567	dGTP binding	molecular_function	Binding to dGTP, deoxyguanosine triphosphate.
GO:0032570	response to progesterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
GO:0032571	response to vitamin K	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
GO:0032572	response to menaquinone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.
GO:0032573	response to phylloquinone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.
GO:0032574	5'-3' RNA helicase activity	molecular_function	Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
GO:0032576	O-linoleoyltransferase activity	molecular_function	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.
GO:0032577	phosphatidylcholine:cardiolipin O-linoleoyltransferase activity	molecular_function	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.
GO:0032578	aleurone grain membrane	cellular_component	The lipid bilayer surrounding an aleurone grain.
GO:0032579	apical lamina of hyaline layer	cellular_component	A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.
GO:0032580	Golgi cisterna membrane	cellular_component	The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
GO:0032581	ER-dependent peroxisome organization	biological_process	A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.
GO:0032584	growth cone membrane	cellular_component	The portion of the plasma membrane surrounding a growth cone.
GO:0032585	multivesicular body membrane	cellular_component	The lipid bilayer surrounding a multivesicular body.
GO:0032586	protein storage vacuole membrane	cellular_component	The lipid bilayer surrounding a protein storage vacuole.
GO:0032587	ruffle membrane	cellular_component	The portion of the plasma membrane surrounding a ruffle.
GO:0032588	trans-Golgi network membrane	cellular_component	The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
GO:0032589	neuron projection membrane	cellular_component	The portion of the plasma membrane surrounding a neuron projection.
GO:0032590	dendrite membrane	cellular_component	The portion of the plasma membrane surrounding a dendrite.
GO:0032591	dendritic spine membrane	cellular_component	The portion of the plasma membrane surrounding a dendritic spine.
GO:0032593	insulin-responsive compartment	cellular_component	A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
GO:0032594	protein transport within lipid bilayer	biological_process	The directed movement of a protein from one location to another within a lipid bilayer.
GO:0032595	B cell receptor transport within lipid bilayer	biological_process	The directed movement of a B cell receptor within a lipid bilayer.
GO:0032596	protein transport into membrane raft	biological_process	The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
GO:0032597	B cell receptor transport into membrane raft	biological_process	The directed movement of a B cell receptor into a membrane raft.
GO:0032598	B cell receptor transport into immunological synapse	biological_process	The directed movement of a B cell receptor into an immunological synapse.
GO:0032599	protein transport out of membrane raft	biological_process	The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
GO:0032600	chemokine receptor transport out of membrane raft	biological_process	The directed movement of a chemokine receptor out of a membrane raft.
GO:0032601	connective tissue growth factor production	biological_process	The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032602	chemokine production	biological_process	The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0032603	fractalkine production	biological_process	The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032604	granulocyte macrophage colony-stimulating factor production	biological_process	The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032605	hepatocyte growth factor production	biological_process	The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032606	type I interferon production	biological_process	The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0032607	interferon-alpha production	biological_process	The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032608	interferon-beta production	biological_process	The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032609	type II interferon production	biological_process	The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.
GO:0032610	interleukin-1 alpha production	biological_process	The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032611	interleukin-1 beta production	biological_process	The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032612	interleukin-1 production	biological_process	The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032613	interleukin-10 production	biological_process	The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032614	interleukin-11 production	biological_process	The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032615	interleukin-12 production	biological_process	The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032616	interleukin-13 production	biological_process	The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032618	interleukin-15 production	biological_process	The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032619	interleukin-16 production	biological_process	The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032620	interleukin-17 production	biological_process	The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032621	interleukin-18 production	biological_process	The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032622	interleukin-19 production	biological_process	The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032623	interleukin-2 production	biological_process	The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032624	interleukin-20 production	biological_process	The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032625	interleukin-21 production	biological_process	The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032626	interleukin-22 production	biological_process	The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032627	interleukin-23 production	biological_process	The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032628	interleukin-24 production	biological_process	The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032629	interleukin-25 production	biological_process	The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032630	interleukin-26 production	biological_process	The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032631	interleukin-27 production	biological_process	The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032632	interleukin-3 production	biological_process	The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032633	interleukin-4 production	biological_process	The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032634	interleukin-5 production	biological_process	The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032635	interleukin-6 production	biological_process	The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032636	interleukin-7 production	biological_process	The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032637	interleukin-8 production	biological_process	The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032638	interleukin-9 production	biological_process	The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032639	TRAIL production	biological_process	The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032640	tumor necrosis factor production	biological_process	The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
GO:0032641	lymphotoxin A production	biological_process	The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
GO:0032642	regulation of chemokine production	biological_process	Any process that modulates the frequency, rate, or extent of chemokine production.
GO:0032643	regulation of connective tissue growth factor production	biological_process	Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.
GO:0032644	regulation of fractalkine production	biological_process	Any process that modulates the frequency, rate, or extent of fractalkine production.
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	biological_process	Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
GO:0032646	regulation of hepatocyte growth factor production	biological_process	Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production.
GO:0032647	regulation of interferon-alpha production	biological_process	Any process that modulates the frequency, rate, or extent of interferon-alpha production.
GO:0032648	regulation of interferon-beta production	biological_process	Any process that modulates the frequency, rate, or extent of interferon-beta production.
GO:0032649	regulation of type II interferon production	biological_process	Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
GO:0032650	regulation of interleukin-1 alpha production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production.
GO:0032651	regulation of interleukin-1 beta production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.
GO:0032652	regulation of interleukin-1 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-1 production.
GO:0032653	regulation of interleukin-10 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-10 production.
GO:0032654	regulation of interleukin-11 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-11 production.
GO:0032655	regulation of interleukin-12 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-12 production.
GO:0032656	regulation of interleukin-13 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-13 production.
GO:0032658	regulation of interleukin-15 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-15 production.
GO:0032659	regulation of interleukin-16 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-16 production.
GO:0032660	regulation of interleukin-17 production	biological_process	Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0032661	regulation of interleukin-18 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-18 production.
GO:0032662	regulation of interleukin-19 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-19 production.
GO:0032663	regulation of interleukin-2 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-2 production.
GO:0032664	regulation of interleukin-20 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-20 production.
GO:0032665	regulation of interleukin-21 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-21 production.
GO:0032666	regulation of interleukin-22 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-22 production.
GO:0032667	regulation of interleukin-23 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-23 production.
GO:0032668	regulation of interleukin-24 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-24 production.
GO:0032669	regulation of interleukin-25 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-25 production.
GO:0032670	regulation of interleukin-26 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-26 production.
GO:0032671	regulation of interleukin-27 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-27 production.
GO:0032672	regulation of interleukin-3 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-3 production.
GO:0032673	regulation of interleukin-4 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-4 production.
GO:0032674	regulation of interleukin-5 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-5 production.
GO:0032675	regulation of interleukin-6 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-6 production.
GO:0032676	regulation of interleukin-7 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-7 production.
GO:0032677	regulation of interleukin-8 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-8 production.
GO:0032678	regulation of interleukin-9 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-9 production.
GO:0032679	regulation of TRAIL production	biological_process	Any process that modulates the frequency, rate, or extent of TRAIL production.
GO:0032680	regulation of tumor necrosis factor production	biological_process	Any process that modulates the frequency, rate or extent of tumor necrosis factor production.
GO:0032681	regulation of lymphotoxin A production	biological_process	Any process that modulates the frequency, rate, or extent of lymphotoxin A production.
GO:0032682	negative regulation of chemokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.
GO:0032683	negative regulation of connective tissue growth factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.
GO:0032684	negative regulation of fractalkine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.
GO:0032685	negative regulation of granulocyte macrophage colony-stimulating factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
GO:0032686	negative regulation of hepatocyte growth factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.
GO:0032687	negative regulation of interferon-alpha production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.
GO:0032688	negative regulation of interferon-beta production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
GO:0032689	negative regulation of type II interferon production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
GO:0032690	negative regulation of interleukin-1 alpha production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.
GO:0032691	negative regulation of interleukin-1 beta production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.
GO:0032692	negative regulation of interleukin-1 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.
GO:0032693	negative regulation of interleukin-10 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.
GO:0032694	negative regulation of interleukin-11 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.
GO:0032695	negative regulation of interleukin-12 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.
GO:0032696	negative regulation of interleukin-13 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.
GO:0032698	negative regulation of interleukin-15 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.
GO:0032699	negative regulation of interleukin-16 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.
GO:0032700	negative regulation of interleukin-17 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0032701	negative regulation of interleukin-18 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.
GO:0032702	negative regulation of interleukin-19 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.
GO:0032703	negative regulation of interleukin-2 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.
GO:0032704	negative regulation of interleukin-20 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.
GO:0032705	negative regulation of interleukin-21 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.
GO:0032706	negative regulation of interleukin-22 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.
GO:0032707	negative regulation of interleukin-23 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.
GO:0032708	negative regulation of interleukin-24 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.
GO:0032709	negative regulation of interleukin-25 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.
GO:0032710	negative regulation of interleukin-26 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.
GO:0032711	negative regulation of interleukin-27 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.
GO:0032712	negative regulation of interleukin-3 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.
GO:0032713	negative regulation of interleukin-4 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.
GO:0032714	negative regulation of interleukin-5 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.
GO:0032715	negative regulation of interleukin-6 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.
GO:0032716	negative regulation of interleukin-7 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.
GO:0032717	negative regulation of interleukin-8 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.
GO:0032718	negative regulation of interleukin-9 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.
GO:0032719	negative regulation of TRAIL production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production.
GO:0032720	negative regulation of tumor necrosis factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
GO:0032721	negative regulation of lymphotoxin A production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.
GO:0032722	positive regulation of chemokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of chemokine production.
GO:0032723	positive regulation of connective tissue growth factor production	biological_process	Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.
GO:0032724	positive regulation of fractalkine production	biological_process	Any process that activates or increases the frequency, rate, or extent of fractalkine production.
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	biological_process	Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
GO:0032726	positive regulation of hepatocyte growth factor production	biological_process	Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.
GO:0032727	positive regulation of interferon-alpha production	biological_process	Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.
GO:0032728	positive regulation of interferon-beta production	biological_process	Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
GO:0032729	positive regulation of type II interferon production	biological_process	Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
GO:0032730	positive regulation of interleukin-1 alpha production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.
GO:0032731	positive regulation of interleukin-1 beta production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.
GO:0032732	positive regulation of interleukin-1 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.
GO:0032733	positive regulation of interleukin-10 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.
GO:0032734	positive regulation of interleukin-11 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.
GO:0032735	positive regulation of interleukin-12 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
GO:0032736	positive regulation of interleukin-13 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
GO:0032738	positive regulation of interleukin-15 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.
GO:0032739	positive regulation of interleukin-16 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.
GO:0032740	positive regulation of interleukin-17 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0032741	positive regulation of interleukin-18 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.
GO:0032742	positive regulation of interleukin-19 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.
GO:0032743	positive regulation of interleukin-2 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.
GO:0032744	positive regulation of interleukin-20 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.
GO:0032745	positive regulation of interleukin-21 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.
GO:0032746	positive regulation of interleukin-22 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.
GO:0032747	positive regulation of interleukin-23 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.
GO:0032748	positive regulation of interleukin-24 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.
GO:0032749	positive regulation of interleukin-25 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.
GO:0032750	positive regulation of interleukin-26 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.
GO:0032751	positive regulation of interleukin-27 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.
GO:0032752	positive regulation of interleukin-3 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.
GO:0032753	positive regulation of interleukin-4 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
GO:0032754	positive regulation of interleukin-5 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
GO:0032755	positive regulation of interleukin-6 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
GO:0032756	positive regulation of interleukin-7 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.
GO:0032757	positive regulation of interleukin-8 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
GO:0032758	positive regulation of interleukin-9 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.
GO:0032759	positive regulation of TRAIL production	biological_process	Any process that activates or increases the frequency, rate, or extent of TRAIL production.
GO:0032760	positive regulation of tumor necrosis factor production	biological_process	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production.
GO:0032761	positive regulation of lymphotoxin A production	biological_process	Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.
GO:0032762	mast cell cytokine production	biological_process	Any process that contributes to cytokine production by a mast cell.
GO:0032763	regulation of mast cell cytokine production	biological_process	Any process that modulates the frequency, rate, or extent of mast cell cytokine production.
GO:0032764	negative regulation of mast cell cytokine production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.
GO:0032765	positive regulation of mast cell cytokine production	biological_process	Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.
GO:0032766	NHE3/E3KARP/ACTN4 complex	cellular_component	A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.
GO:0032767	copper-dependent protein binding	molecular_function	Binding to a protein or protein complex, in the presence of copper.
GO:0032768	regulation of monooxygenase activity	biological_process	Any process that modulates the activity of a monooxygenase.
GO:0032769	negative regulation of monooxygenase activity	biological_process	Any process that stops or reduces the activity of a monooxygenase.
GO:0032770	positive regulation of monooxygenase activity	biological_process	Any process that activates or increases the activity of a monooxygenase.
GO:0032771	regulation of tyrosinase activity	biological_process	Any process that modulates the activity of a tyrosinase enzyme.
GO:0032772	negative regulation of tyrosinase activity	biological_process	Any process that stops or reduces the activity of a tyrosinase enzyme.
GO:0032773	positive regulation of tyrosinase activity	biological_process	Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase.
GO:0032774	RNA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
GO:0032775	DNA methylation on adenine	biological_process	The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule.
GO:0032776	DNA methylation on cytosine	biological_process	The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
GO:0032777	Piccolo NuA4 histone acetyltransferase complex	cellular_component	A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.
GO:0032778	P-type cobalt transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in).
GO:0032780	negative regulation of ATP-dependent activity	biological_process	Any process that stops or reduces the rate of an ATP-dependent activity.
GO:0032781	positive regulation of ATP-dependent activity	biological_process	Any process that activates or increases the rate of an ATP-dependent activity.
GO:0032782	bile acid secretion	biological_process	The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.
GO:0032783	super elongation complex	cellular_component	A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.
GO:0032784	regulation of DNA-templated transcription elongation	biological_process	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
GO:0032785	negative regulation of DNA-templated transcription, elongation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
GO:0032786	positive regulation of DNA-templated transcription, elongation	biological_process	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
GO:0032787	monocarboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
GO:0032788	saturated monocarboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.
GO:0032789	unsaturated monocarboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.
GO:0032790	ribosome disassembly	biological_process	The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
GO:0032791	lead ion binding	molecular_function	Binding to lead (Pb) ions.
GO:0032792	negative regulation of CREB transcription factor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.
GO:0032793	positive regulation of CREB transcription factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.
GO:0032794	GTPase activating protein binding	molecular_function	Binding to a GTPase activating protein.
GO:0032795	heterotrimeric G-protein binding	molecular_function	Binding to a heterotrimeric G-protein.
GO:0032796	uropod organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.
GO:0032797	SMN complex	cellular_component	A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.
GO:0032798	Swi5-Sfr1 complex	cellular_component	A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).
GO:0032799	low-density lipoprotein receptor particle metabolic process	biological_process	The chemical reactions and pathways involving low-density lipoprotein receptors.
GO:0032801	receptor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0032802	low-density lipoprotein particle receptor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.
GO:0032806	carboxy-terminal domain protein kinase complex	cellular_component	A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.
GO:0032807	DNA ligase IV complex	cellular_component	A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.
GO:0032808	lacrimal gland development	biological_process	The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.
GO:0032809	neuronal cell body membrane	cellular_component	The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
GO:0032810	sterol response element binding	molecular_function	Binding to a sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
GO:0032811	negative regulation of epinephrine secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.
GO:0032812	positive regulation of epinephrine secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.
GO:0032813	tumor necrosis factor receptor superfamily binding	molecular_function	Binding to a member of the tumor necrosis factor receptor superfamily.
GO:0032814	regulation of natural killer cell activation	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell activation.
GO:0032815	negative regulation of natural killer cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.
GO:0032816	positive regulation of natural killer cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
GO:0032817	regulation of natural killer cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell proliferation.
GO:0032818	negative regulation of natural killer cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.
GO:0032819	positive regulation of natural killer cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.
GO:0032820	regulation of natural killer cell proliferation involved in immune response	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
GO:0032821	negative regulation of natural killer cell proliferation involved in immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
GO:0032822	positive regulation of natural killer cell proliferation involved in immune response	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
GO:0032823	regulation of natural killer cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell differentiation.
GO:0032824	negative regulation of natural killer cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.
GO:0032825	positive regulation of natural killer cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.
GO:0032826	regulation of natural killer cell differentiation involved in immune response	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
GO:0032827	negative regulation of natural killer cell differentiation involved in immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
GO:0032828	positive regulation of natural killer cell differentiation involved in immune response	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
GO:0032830	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
GO:0032832	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	biological_process	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
GO:0032833	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	biological_process	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
GO:0032835	glomerulus development	biological_process	The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
GO:0032836	glomerular basement membrane development	biological_process	The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.
GO:0032837	distributive segregation	biological_process	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.
GO:0032838	plasma membrane bounded cell projection cytoplasm	cellular_component	All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
GO:0032839	dendrite cytoplasm	cellular_component	All of the contents of a dendrite, excluding the surrounding plasma membrane.
GO:0032840	intramolecular proline-rich ligand binding	molecular_function	Binding to a proline-rich region within the same polypeptide.
GO:0032841	calcitonin binding	molecular_function	Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.
GO:0032843	hydroperoxide reductase activity	molecular_function	Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
GO:0032847	regulation of cellular pH reduction	biological_process	Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.
GO:0032848	negative regulation of cellular pH reduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.
GO:0032849	positive regulation of cellular pH reduction	biological_process	Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
GO:0032865	ERMES complex	cellular_component	A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
GO:0032866	D-xylose:NADP reductase activity	molecular_function	Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.
GO:0032867	L-arabinose:NADP reductase activity	molecular_function	Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+.
GO:0032868	response to insulin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
GO:0032869	cellular response to insulin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
GO:0032870	cellular response to hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
GO:0032871	regulation of karyogamy	biological_process	Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.
GO:0032872	regulation of stress-activated MAPK cascade	biological_process	Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
GO:0032873	negative regulation of stress-activated MAPK cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
GO:0032874	positive regulation of stress-activated MAPK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
GO:0032875	regulation of DNA endoreduplication	biological_process	Any process that modulates the frequency, rate or extent of DNA endoreduplication.
GO:0032876	negative regulation of DNA endoreduplication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
GO:0032877	positive regulation of DNA endoreduplication	biological_process	Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
GO:0032878	regulation of establishment or maintenance of cell polarity	biological_process	Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
GO:0032879	regulation of localization	biological_process	Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GO:0032880	regulation of protein localization	biological_process	Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
GO:0032881	regulation of polysaccharide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.
GO:0032882	regulation of chitin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.
GO:0032883	regulation of chitin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.
GO:0032884	regulation of cell wall chitin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.
GO:0032885	regulation of polysaccharide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.
GO:0032886	regulation of microtubule-based process	biological_process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
GO:0032887	regulation of spindle elongation	biological_process	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.
GO:0032888	regulation of mitotic spindle elongation	biological_process	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
GO:0032889	regulation of vacuole fusion, non-autophagic	biological_process	Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
GO:0032890	regulation of organic acid transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032891	negative regulation of organic acid transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032892	positive regulation of organic acid transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0032896	palmitoyl-CoA 9-desaturase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O.
GO:0032897	negative regulation of viral transcription	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
GO:0032898	neurotrophin production	biological_process	The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
GO:0032899	regulation of neurotrophin production	biological_process	Any process that modulates the frequency, rate, or extent of production of a neurotrophin.
GO:0032900	negative regulation of neurotrophin production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.
GO:0032901	positive regulation of neurotrophin production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.
GO:0032902	nerve growth factor production	biological_process	The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.
GO:0032903	regulation of nerve growth factor production	biological_process	Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).
GO:0032904	negative regulation of nerve growth factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).
GO:0032905	transforming growth factor beta1 production	biological_process	The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032906	transforming growth factor beta2 production	biological_process	The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032907	transforming growth factor beta3 production	biological_process	The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032908	regulation of transforming growth factor beta1 production	biological_process	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.
GO:0032909	regulation of transforming growth factor beta2 production	biological_process	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
GO:0032910	regulation of transforming growth factor beta3 production	biological_process	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.
GO:0032911	negative regulation of transforming growth factor beta1 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.
GO:0032912	negative regulation of transforming growth factor beta2 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.
GO:0032913	negative regulation of transforming growth factor beta3 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.
GO:0032914	positive regulation of transforming growth factor beta1 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
GO:0032915	positive regulation of transforming growth factor beta2 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.
GO:0032916	positive regulation of transforming growth factor beta3 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.
GO:0032917	polyamine acetylation	biological_process	The modification of polyamines by addition of acetyl groups.
GO:0032918	spermidine acetylation	biological_process	The modification of spermidine by addition of acetyl groups.
GO:0032919	spermine acetylation	biological_process	The modification of spermine by addition of acetyl groups.
GO:0032920	putrescine acetylation	biological_process	The modification of putrescine by addition of acetyl groups.
GO:0032921	sarcosine oxidase complex	cellular_component	A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.
GO:0032922	circadian regulation of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
GO:0032923	organic phosphonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
GO:0032924	activin receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0032925	regulation of activin receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
GO:0032926	negative regulation of activin receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
GO:0032927	positive regulation of activin receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
GO:0032928	regulation of superoxide anion generation	biological_process	Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.
GO:0032929	negative regulation of superoxide anion generation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.
GO:0032930	positive regulation of superoxide anion generation	biological_process	Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
GO:0032931	histone H3K56 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).
GO:0032932	negative regulation of astral microtubule depolymerization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.
GO:0032933	SREBP signaling pathway	biological_process	The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.
GO:0032934	sterol binding	molecular_function	Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
GO:0032935	sterol sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a sterol.
GO:0032936	SREBP-SCAP complex	cellular_component	A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.
GO:0032937	SREBP-SCAP-Insig complex	cellular_component	A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.
GO:0032938	negative regulation of translation in response to oxidative stress	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0032939	positive regulation of translation in response to oxidative stress	biological_process	Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0032940	secretion by cell	biological_process	The controlled release of a substance by a cell.
GO:0032941	secretion by tissue	biological_process	The controlled release of a substance by a tissue.
GO:0032942	inositol tetrakisphosphate 2-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP.
GO:0032943	mononuclear cell proliferation	biological_process	The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.
GO:0032944	regulation of mononuclear cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.
GO:0032945	negative regulation of mononuclear cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.
GO:0032946	positive regulation of mononuclear cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.
GO:0032948	regulation of alpha-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.
GO:0032949	regulation of alpha-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.
GO:0032950	regulation of beta-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.
GO:0032951	regulation of beta-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.
GO:0032952	regulation of (1->3)-beta-D-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.
GO:0032953	regulation of (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
GO:0032954	regulation of cytokinetic process	biological_process	Any process that modulates the frequency, rate or extent of a cytokinetic process.
GO:0032955	regulation of division septum assembly	biological_process	Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0032956	regulation of actin cytoskeleton organization	biological_process	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
GO:0032957	inositol trisphosphate metabolic process	biological_process	The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
GO:0032958	inositol phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0032959	inositol trisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
GO:0032960	regulation of inositol trisphosphate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
GO:0032961	negative regulation of inositol trisphosphate biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
GO:0032963	collagen metabolic process	biological_process	The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
GO:0032964	collagen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
GO:0032965	regulation of collagen biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0032966	negative regulation of collagen biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0032967	positive regulation of collagen biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
GO:0032968	positive regulation of transcription elongation by RNA polymerase II	biological_process	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
GO:0032969	endosomal scaffold complex	cellular_component	A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.
GO:0032970	regulation of actin filament-based process	biological_process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
GO:0032971	regulation of muscle filament sliding	biological_process	Any process that modulates the frequency, rate or extent of muscle filament sliding.
GO:0032972	regulation of muscle filament sliding speed	biological_process	Any process that modulates the velocity of muscle filament sliding.
GO:0032973	amino acid export across plasma membrane	biological_process	The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0032974	amino acid transmembrane export from vacuole	biological_process	The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
GO:0032975	amino acid transmembrane import into vacuole	biological_process	The directed movement of amino acids into the vacuole across the vacuolar membrane.
GO:0032976	release of matrix enzymes from mitochondria	biological_process	The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.
GO:0032977	membrane insertase activity	molecular_function	Binds transmembrane domain-containing proteins and mediates their integration into a membrane.
GO:0032978	protein insertion into membrane from inner side	biological_process	The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.
GO:0032979	protein insertion into mitochondrial inner membrane from matrix	biological_process	The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.
GO:0032980	keratinocyte activation	biological_process	A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
GO:0032981	mitochondrial respiratory chain complex I assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
GO:0032982	myosin filament	cellular_component	A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.
GO:0032983	kainate selective glutamate receptor complex	cellular_component	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.
GO:0032984	protein-containing complex disassembly	biological_process	The disaggregation of a protein-containing macromolecular complex into its constituent components.
GO:0032985	protein-carbohydrate complex disassembly	biological_process	The disaggregation of a protein-carbohydrate complex into its constituent components.
GO:0032986	protein-DNA complex disassembly	biological_process	The disaggregation of a protein-DNA complex into its constituent components.
GO:0032987	protein-lipid complex disassembly	biological_process	The disaggregation of a protein-lipid complex into its constituent components.
GO:0032988	protein-RNA complex disassembly	biological_process	The disaggregation of a protein-RNA complex into its constituent components.
GO:0032989	cellular component morphogenesis	biological_process	The process in which cellular structures, including whole cells or cell parts, are generated and organized.
GO:0032990	cell part morphogenesis	biological_process	The process in which the anatomical structures of a cell part are generated and organized.
GO:0032991	protein-containing complex	cellular_component	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0032992	protein-carbohydrate complex	cellular_component	A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other.
GO:0032993	protein-DNA complex	cellular_component	A macromolecular complex containing both protein and DNA molecules.
GO:0032994	protein-lipid complex	cellular_component	A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other.
GO:0032995	regulation of fungal-type cell wall biogenesis	biological_process	Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.
GO:0032996	Bcl3-Bcl10 complex	cellular_component	A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.
GO:0032997	Fc receptor complex	cellular_component	A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.
GO:0032998	Fc-epsilon receptor I complex	cellular_component	A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.
GO:0032999	Fc-alpha receptor I complex	cellular_component	A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.
GO:0033000	Fc-gamma receptor I complex	cellular_component	A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.
GO:0033001	Fc-gamma receptor III complex	cellular_component	A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.
GO:0033002	muscle cell proliferation	biological_process	The expansion of a muscle cell population by cell division.
GO:0033003	regulation of mast cell activation	biological_process	Any process that modulates the frequency, rate, or extent of mast cell activation.
GO:0033004	negative regulation of mast cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.
GO:0033005	positive regulation of mast cell activation	biological_process	Any process that activates or increases the frequency, rate, or extent of mast cell activation.
GO:0033006	regulation of mast cell activation involved in immune response	biological_process	Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.
GO:0033007	negative regulation of mast cell activation involved in immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.
GO:0033008	positive regulation of mast cell activation involved in immune response	biological_process	Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.
GO:0033009	nucleomorph	cellular_component	A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.
GO:0033010	paranodal junction	cellular_component	A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
GO:0033011	perinuclear theca	cellular_component	A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins.
GO:0033012	porosome	cellular_component	A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.
GO:0033013	tetrapyrrole metabolic process	biological_process	The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
GO:0033014	tetrapyrrole biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
GO:0033015	tetrapyrrole catabolic process	biological_process	The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
GO:0033016	rhoptry membrane	cellular_component	The lipid bilayer surrounding a rhoptry.
GO:0033017	sarcoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the sarcoplasmic reticulum.
GO:0033018	sarcoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the sarcoplasmic reticulum.
GO:0033019	5-hydroxyvalerate dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH.
GO:0033020	cyclopentanol metabolic process	biological_process	The chemical reactions and pathways involving cyclopentanol.
GO:0033021	cyclopentanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyclopentanol.
GO:0033022	cyclopentanol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyclopentanol.
GO:0033023	mast cell homeostasis	biological_process	The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0033024	mast cell apoptotic process	biological_process	Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
GO:0033025	regulation of mast cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.
GO:0033026	negative regulation of mast cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.
GO:0033027	positive regulation of mast cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.
GO:0033028	myeloid cell apoptotic process	biological_process	Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
GO:0033029	regulation of neutrophil apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.
GO:0033030	negative regulation of neutrophil apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.
GO:0033031	positive regulation of neutrophil apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.
GO:0033032	regulation of myeloid cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.
GO:0033033	negative regulation of myeloid cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.
GO:0033034	positive regulation of myeloid cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.
GO:0033036	macromolecule localization	biological_process	Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0033037	polysaccharide localization	biological_process	Any process in which a polysaccharide is transported to, or maintained in, a specific location.
GO:0033038	bitter taste receptor activity	molecular_function	Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.
GO:0033039	ionotropic salty taste receptor activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a soluble salty compound has been bound by the channel complex or one of its constituent parts.
GO:0033040	sour taste receptor activity	molecular_function	Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.
GO:0033041	sweet taste receptor activity	molecular_function	Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.
GO:0033042	umami taste receptor activity	molecular_function	Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.
GO:0033043	regulation of organelle organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GO:0033044	regulation of chromosome organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
GO:0033045	regulation of sister chromatid segregation	biological_process	Any process that modulates the frequency, rate or extent of sister chromatid segregation.
GO:0033046	negative regulation of sister chromatid segregation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.
GO:0033047	regulation of mitotic sister chromatid segregation	biological_process	Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.
GO:0033048	negative regulation of mitotic sister chromatid segregation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.
GO:0033049	clavulanic acid metabolic process	biological_process	The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.
GO:0033050	clavulanic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.
GO:0033051	aminophosphonate metabolic process	biological_process	The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.
GO:0033052	cyanoamino acid metabolic process	biological_process	The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.
GO:0033053	D-glutamine metabolic process	biological_process	The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.
GO:0033054	D-glutamate metabolic process	biological_process	The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.
GO:0033055	D-arginine metabolic process	biological_process	The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid.
GO:0033056	D-ornithine metabolic process	biological_process	The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid.
GO:0033058	directional locomotion	biological_process	Self-propelled movement of a cell or organism from one location to another along an axis.
GO:0033059	cellular pigmentation	biological_process	The deposition or aggregation of coloring matter in a cell.
GO:0033060	ocellus pigmentation	biological_process	The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.
GO:0033061	DNA recombinase mediator complex	cellular_component	A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange.
GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	cellular_component	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.
GO:0033064	XRCC2-RAD51D complex	cellular_component	A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.
GO:0033065	Rad51C-XRCC3 complex	cellular_component	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.
GO:0033066	Rad51B-Rad51C complex	cellular_component	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.
GO:0033067	macrolide metabolic process	biological_process	The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
GO:0033068	macrolide biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
GO:0033069	ansamycin metabolic process	biological_process	The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.
GO:0033070	ansamycin biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.
GO:0033071	vancomycin metabolic process	biological_process	The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.
GO:0033072	vancomycin biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.
GO:0033073	pinene metabolic process	biological_process	The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.
GO:0033074	pinene catabolic process	biological_process	The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.
GO:0033075	isoquinoline alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
GO:0033076	isoquinoline alkaloid metabolic process	biological_process	The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
GO:0033077	T cell differentiation in thymus	biological_process	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
GO:0033078	extrathymic T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
GO:0033079	immature T cell proliferation	biological_process	The expansion of an immature T cell population by cell division.
GO:0033080	immature T cell proliferation in thymus	biological_process	The expansion of an immature T cell population by cell division in the thymus.
GO:0033081	regulation of T cell differentiation in thymus	biological_process	Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
GO:0033082	regulation of extrathymic T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.
GO:0033083	regulation of immature T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of immature T cell proliferation.
GO:0033084	regulation of immature T cell proliferation in thymus	biological_process	Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.
GO:0033085	negative regulation of T cell differentiation in thymus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
GO:0033086	negative regulation of extrathymic T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.
GO:0033087	negative regulation of immature T cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.
GO:0033088	negative regulation of immature T cell proliferation in thymus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.
GO:0033089	positive regulation of T cell differentiation in thymus	biological_process	Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.
GO:0033090	positive regulation of extrathymic T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.
GO:0033091	positive regulation of immature T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.
GO:0033092	positive regulation of immature T cell proliferation in thymus	biological_process	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.
GO:0033093	Weibel-Palade body	cellular_component	A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.
GO:0033094	butane-1,4-diamine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.
GO:0033095	aleurone grain	cellular_component	A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.
GO:0033096	amyloplast envelope	cellular_component	The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0033097	amyloplast membrane	cellular_component	Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.
GO:0033098	amyloplast inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.
GO:0033099	attachment organelle	cellular_component	A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.
GO:0033100	NuA3 histone acetyltransferase complex	cellular_component	A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.
GO:0033101	cellular bud membrane	cellular_component	The portion of the plasma membrane surrounding a cellular bud.
GO:0033102	acidocalcisome membrane	cellular_component	The lipid bilayer surrounding an acidocalcisome.
GO:0033103	protein secretion by the type VI secretion system	biological_process	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.
GO:0033104	type VI protein secretion system complex	cellular_component	A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.
GO:0033105	chlorosome envelope	cellular_component	The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.
GO:0033106	cis-Golgi network membrane	cellular_component	The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network.
GO:0033107	Cvt vesicle	cellular_component	A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).
GO:0033108	mitochondrial respiratory chain complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.
GO:0033110	Cvt vesicle membrane	cellular_component	Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.
GO:0033111	attachment organelle membrane	cellular_component	The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.
GO:0033112	cyanelle envelope	cellular_component	The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0033113	cyanelle membrane	cellular_component	Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.
GO:0033114	cyanelle thylakoid lumen	cellular_component	The volume enclosed by a cyanelle thylakoid membrane.
GO:0033115	cyanelle thylakoid membrane	cellular_component	The lipid bilayer membrane of any thylakoid within a cyanelle.
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	cellular_component	The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
GO:0033117	esterosome	cellular_component	A vesicle filled with crystalline protein that shows sequence similarities with various esterases.
GO:0033118	esterosome membrane	cellular_component	The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.
GO:0033119	negative regulation of RNA splicing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.
GO:0033120	positive regulation of RNA splicing	biological_process	Any process that activates or increases the frequency, rate or extent of RNA splicing.
GO:0033121	regulation of purine nucleotide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
GO:0033122	negative regulation of purine nucleotide catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
GO:0033123	positive regulation of purine nucleotide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
GO:0033130	acetylcholine receptor binding	molecular_function	Binding to an acetylcholine receptor.
GO:0033131	regulation of glucokinase activity	biological_process	Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
GO:0033132	negative regulation of glucokinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
GO:0033133	positive regulation of glucokinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
GO:0033134	ubiquitin activating enzyme binding	molecular_function	Binding to a ubiquitin activating enzyme, any of the E1 proteins.
GO:0033135	regulation of peptidyl-serine phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
GO:0033137	negative regulation of peptidyl-serine phosphorylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
GO:0033138	positive regulation of peptidyl-serine phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein	biological_process	Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	biological_process	Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0033142	nuclear progesterone receptor binding	molecular_function	Binding to a nuclear progesterone receptor.
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0033149	FFAT motif binding	molecular_function	Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
GO:0033150	cytoskeletal calyx	cellular_component	A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.
GO:0033151	V(D)J recombination	biological_process	The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
GO:0033152	immunoglobulin V(D)J recombination	biological_process	The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
GO:0033153	T cell receptor V(D)J recombination	biological_process	The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
GO:0033154	ABC-type oligogalacturonide transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).
GO:0033156	oligogalacturonide transport	biological_process	The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033157	regulation of intracellular protein transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
GO:0033161	mitogen-activated protein kinase kinase kinase kinase binding	molecular_function	Binding to a mitogen-activated protein kinase kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase kinase.
GO:0033162	melanosome membrane	cellular_component	The lipid bilayer surrounding a melanosome.
GO:0033163	microneme membrane	cellular_component	The lipid bilayer surrounding a microneme.
GO:0033164	glycolipid 1,6-alpha-mannosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
GO:0033165	interphotoreceptor matrix	cellular_component	A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.
GO:0033166	hyaline layer	cellular_component	A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.
GO:0033167	ARC complex	cellular_component	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.
GO:0033169	histone H3-K9 demethylation	biological_process	The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.
GO:0033172	gas vesicle shell	cellular_component	The proteinaceous structure surrounding a gas vesicle.
GO:0033173	calcineurin-NFAT signaling cascade	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).
GO:0033174	chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)	cellular_component	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.
GO:0033175	chloroplast proton-transporting ATP synthase complex, coupling factor CF(o)	cellular_component	All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins.
GO:0033176	proton-transporting V-type ATPase complex	cellular_component	A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	cellular_component	A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.
GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	cellular_component	A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.
GO:0033179	proton-transporting V-type ATPase, V0 domain	cellular_component	A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.
GO:0033180	proton-transporting V-type ATPase, V1 domain	cellular_component	A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.
GO:0033181	plasma membrane proton-transporting V-type ATPase complex	cellular_component	A proton-transporting two-sector ATPase complex found in the plasma membrane.
GO:0033182	regulation of histone ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
GO:0033183	negative regulation of histone ubiquitination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
GO:0033184	positive regulation of histone ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
GO:0033185	dolichol-phosphate-mannose synthase complex	cellular_component	A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.
GO:0033186	CAF-1 complex	cellular_component	A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.
GO:0033188	sphingomyelin synthase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.
GO:0033189	response to vitamin A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
GO:0033190	solanapyrone synthase activity	molecular_function	Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.
GO:0033191	macrophomate synthase activity	molecular_function	Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate.
GO:0033192	calmodulin-dependent protein phosphatase activity	molecular_function	Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.
GO:0033193	Lsd1/2 complex	cellular_component	A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.
GO:0033194	response to hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
GO:0033195	response to alkyl hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.
GO:0033196	tryparedoxin peroxidase activity	molecular_function	Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O.
GO:0033197	response to vitamin E	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
GO:0033198	response to ATP	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
GO:0033200	inositol heptakisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.
GO:0033201	alpha-1,4-glucan synthase activity	molecular_function	Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.
GO:0033202	DNA helicase complex	cellular_component	A protein complex that possesses DNA helicase activity.
GO:0033203	DNA helicase A complex	cellular_component	A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.
GO:0033204	ribonuclease P RNA binding	molecular_function	Binding to RNA subunit of ribonuclease P.
GO:0033206	meiotic cytokinesis	biological_process	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.
GO:0033207	beta-1,4-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage.
GO:0033208	UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide.
GO:0033209	tumor necrosis factor-mediated signaling pathway	biological_process	The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0033210	leptin-mediated signaling pathway	biological_process	The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
GO:0033211	adiponectin-activated signaling pathway	biological_process	The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0033212	iron import into cell	biological_process	The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
GO:0033214	siderophore-dependent iron import into cell	biological_process	A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.
GO:0033215	reductive iron assimilation	biological_process	A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.
GO:0033217	regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	biological_process	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
GO:0033218	amide binding	molecular_function	Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
GO:0033219	urea binding	molecular_function	Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2.
GO:0033221	ATPase-coupled urea transmembrane transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).
GO:0033222	xylose binding	molecular_function	Binding to the D- or L-enantiomer of xylose.
GO:0033223	2-aminoethylphosphonate transport	biological_process	The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033225	ATPase-coupled 2-aminoethylphosphonate transporter activity	molecular_function	Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).
GO:0033226	2-aminoethylphosphonate binding	molecular_function	Binding to 2-aminoethylphosphonate.
GO:0033227	dsRNA transport	biological_process	The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033228	cysteine export across plasma membrane	biological_process	The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0033229	cysteine transmembrane transporter activity	molecular_function	Enables the transfer of cysteine from one side of a membrane to the other.
GO:0033230	ABC-type cysteine transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).
GO:0033231	carbohydrate export	biological_process	The directed movement of carbohydrates out of a cell or organelle.
GO:0033232	ABC-type D-methionine transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).
GO:0033233	regulation of protein sumoylation	biological_process	Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.
GO:0033234	negative regulation of protein sumoylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
GO:0033235	positive regulation of protein sumoylation	biological_process	Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
GO:0033238	regulation of amine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.
GO:0033239	negative regulation of amine metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.
GO:0033240	positive regulation of amine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.
GO:0033241	regulation of amine catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GO:0033242	negative regulation of amine catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GO:0033243	positive regulation of amine catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GO:0033244	regulation of penicillin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033245	negative regulation of penicillin metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033246	positive regulation of penicillin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033247	regulation of penicillin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033248	negative regulation of penicillin catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033249	positive regulation of penicillin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0033250	penicillinase activity	molecular_function	Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.
GO:0033251	cephalosporinase activity	molecular_function	Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.
GO:0033252	regulation of beta-lactamase activity	biological_process	Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.
GO:0033253	regulation of penicillinase activity	biological_process	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.
GO:0033254	vacuolar transporter chaperone complex	cellular_component	A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.
GO:0033255	SAS acetyltransferase complex	cellular_component	A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.
GO:0033256	I-kappaB/NF-kappaB complex	cellular_component	A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.
GO:0033257	Bcl3/NF-kappaB2 complex	cellular_component	A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.
GO:0033258	plastid DNA metabolic process	biological_process	The chemical reactions and pathways involving plastid DNA.
GO:0033259	plastid DNA replication	biological_process	The process in which new strands of DNA are synthesized in a plastid.
GO:0033260	nuclear DNA replication	biological_process	The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
GO:0033262	regulation of nuclear cell cycle DNA replication	biological_process	Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
GO:0033263	CORVET complex	cellular_component	A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.
GO:0033265	choline binding	molecular_function	Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.
GO:0033266	ABC-type choline transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
GO:0033268	node of Ranvier	cellular_component	An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.
GO:0033269	internode region of axon	cellular_component	An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.
GO:0033270	paranode region of axon	cellular_component	An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
GO:0033271	myo-inositol phosphate transport	biological_process	The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033272	myo-inositol hexakisphosphate transport	biological_process	The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033273	response to vitamin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
GO:0033274	response to vitamin B2	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
GO:0033275	actin-myosin filament sliding	biological_process	The sliding movement of actin thin filaments and myosin thick filaments past each other.
GO:0033276	transcription factor TFTC complex	cellular_component	A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.
GO:0033278	cell proliferation in midbrain	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.
GO:0033280	response to vitamin D	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
GO:0033281	TAT protein transport complex	cellular_component	A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.
GO:0033282	protein C inhibitor-acrosin complex	cellular_component	A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.
GO:0033283	ATPase-coupled organic acid transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).
GO:0033284	ATPase-coupled carboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).
GO:0033285	ATPase-coupled monocarboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).
GO:0033286	ATPase-coupled ectoine transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).
GO:0033288	ATPase-coupled hydroxyectoine transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).
GO:0033289	intraconoid microtubule	cellular_component	A microtubule located such that it threads through the conoid and projects through the polar ring.
GO:0033290	eukaryotic 48S preinitiation complex	cellular_component	The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC.
GO:0033291	eukaryotic 80S initiation complex	cellular_component	A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.
GO:0033292	T-tubule organization	biological_process	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
GO:0033293	monocarboxylic acid binding	molecular_function	Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).
GO:0033294	ectoine binding	molecular_function	Binding to ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.
GO:0033295	hydroxyectoine binding	molecular_function	Binding to hydroxyectoine.
GO:0033296	rhamnose binding	molecular_function	Binding to the D- or L-enantiomer of rhamnose.
GO:0033298	contractile vacuole organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.
GO:0033299	secretion of lysosomal enzymes	biological_process	The controlled release of lysosomal enzymes by a cell.
GO:0033300	dehydroascorbic acid transmembrane transporter activity	molecular_function	Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.
GO:0033301	cell cycle comprising mitosis without cytokinesis	biological_process	A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).
GO:0033302	quercetin O-glucoside metabolic process	biological_process	The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.
GO:0033303	quercetin O-glucoside biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.
GO:0033304	chlorophyll a metabolic process	biological_process	The chemical reactions and pathways involving chlorophyll a.
GO:0033305	chlorophyll a biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of chlorophyll a.
GO:0033306	phytol metabolic process	biological_process	The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
GO:0033307	phytol salvage	biological_process	A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.
GO:0033308	hydroxyectoine transport	biological_process	The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033309	SBF transcription complex	cellular_component	A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p.
GO:0033310	chlorophyll a catabolic process	biological_process	The chemical reactions and pathways leading to the breakdown of chlorophyll a.
GO:0033311	chlorophyll a biosynthetic process via phytyl diphosphate	biological_process	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.
GO:0033312	chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a	biological_process	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.
GO:0033313	meiotic cell cycle checkpoint signaling	biological_process	A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
GO:0033314	mitotic DNA replication checkpoint signaling	biological_process	A signal transduction process that contributes to a mitotic DNA replication checkpoint.
GO:0033315	meiotic G2/MI DNA replication checkpoint signaling	biological_process	A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete.
GO:0033316	meiotic spindle assembly checkpoint signaling	biological_process	A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.
GO:0033319	UDP-D-xylose metabolic process	biological_process	The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.
GO:0033320	UDP-D-xylose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.
GO:0033321	homomethionine metabolic process	biological_process	The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.
GO:0033322	homomethionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.
GO:0033323	choline biosynthetic process via CDP-choline	biological_process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.
GO:0033324	choline biosynthetic process via N-monomethylethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.
GO:0033325	choline biosynthetic process via phosphoryl-ethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.
GO:0033326	cerebrospinal fluid secretion	biological_process	The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.
GO:0033327	Leydig cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
GO:0033328	peroxisome membrane targeting sequence binding	molecular_function	Binding to a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.
GO:0033329	kaempferol O-glucoside metabolic process	biological_process	The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol.
GO:0033330	kaempferol O-glucoside biosynthetic process	biological_process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.
GO:0033331	ent-kaurene metabolic process	biological_process	The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.
GO:0033332	ent-kaurene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.
GO:0033333	fin development	biological_process	The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
GO:0033334	fin morphogenesis	biological_process	The process in which the anatomical structures of a fin are generated and organized.
GO:0033335	anal fin development	biological_process	The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.
GO:0033336	caudal fin development	biological_process	The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.
GO:0033337	dorsal fin development	biological_process	The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.
GO:0033338	medial fin development	biological_process	The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.
GO:0033339	pectoral fin development	biological_process	The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
GO:0033340	pelvic fin development	biological_process	The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.
GO:0033341	regulation of collagen binding	biological_process	Any process that modulates the frequency, rate or extent of collagen binding.
GO:0033342	negative regulation of collagen binding	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.
GO:0033343	positive regulation of collagen binding	biological_process	Any process that activates or increases the frequency, rate or extent of collagen binding.
GO:0033344	cholesterol efflux	biological_process	The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
GO:0033345	asparagine catabolic process via L-aspartate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
GO:0033346	asparagine catabolic process via 2-oxosuccinamate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.
GO:0033347	tetrose metabolic process	biological_process	The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
GO:0033348	tetrose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
GO:0033349	apiose metabolic process	biological_process	The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
GO:0033350	apiose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
GO:0033351	UDP-D-apiose metabolic process	biological_process	The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.
GO:0033352	UDP-D-apiose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.
GO:0033353	S-adenosylmethionine cycle	biological_process	A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.
GO:0033354	chlorophyll cycle	biological_process	A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.
GO:0033355	ascorbate glutathione cycle	biological_process	A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.
GO:0033356	UDP-L-arabinose metabolic process	biological_process	The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.
GO:0033357	L-arabinose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.
GO:0033358	UDP-L-arabinose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.
GO:0033359	lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate	biological_process	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.
GO:0033360	lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate	biological_process	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.
GO:0033361	lysine biosynthetic process via diaminopimelate, dehydrogenase pathway	biological_process	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.
GO:0033362	lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway	biological_process	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.
GO:0033363	secretory granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
GO:0033364	mast cell secretory granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
GO:0033365	protein localization to organelle	biological_process	A process in which a protein is transported to, or maintained in, a location within an organelle.
GO:0033366	protein localization to secretory granule	biological_process	A process in which a protein is transported to, or maintained in, a location within a secretory granule.
GO:0033367	protein localization to mast cell secretory granule	biological_process	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.
GO:0033368	protease localization to mast cell secretory granule	biological_process	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.
GO:0033369	establishment of protein localization to mast cell secretory granule	biological_process	The directed movement of a protein to a location within a secretory granule in a mast cell.
GO:0033370	maintenance of protein location in mast cell secretory granule	biological_process	A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.
GO:0033371	T cell secretory granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
GO:0033372	establishment of protease localization to mast cell secretory granule	biological_process	The directed movement of a protease to a location within a secretory granule in a mast cell.
GO:0033373	maintenance of protease location in mast cell secretory granule	biological_process	A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.
GO:0033374	protein localization to T cell secretory granule	biological_process	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.
GO:0033375	protease localization to T cell secretory granule	biological_process	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.
GO:0033376	establishment of protein localization to T cell secretory granule	biological_process	The directed movement of a protein to a location within a secretory granule in a T cell.
GO:0033377	maintenance of protein location in T cell secretory granule	biological_process	A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
GO:0033378	establishment of protease localization to T cell secretory granule	biological_process	The directed movement of a protease to a location within a secretory granule in a T cell.
GO:0033379	maintenance of protease location in T cell secretory granule	biological_process	A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
GO:0033380	granzyme B localization to T cell secretory granule	biological_process	Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.
GO:0033381	establishment of granzyme B localization to T cell secretory granule	biological_process	The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.
GO:0033382	maintenance of granzyme B location in T cell secretory granule	biological_process	A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
GO:0033383	geranyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.
GO:0033384	geranyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of geranyl diphosphate.
GO:0033385	geranylgeranyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.
GO:0033386	geranylgeranyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.
GO:0033387	putrescine biosynthetic process from ornithine	biological_process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.
GO:0033388	putrescine biosynthetic process from arginine	biological_process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.
GO:0033389	putrescine biosynthetic process from arginine, using agmatinase	biological_process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.
GO:0033390	putrescine biosynthetic process from arginine via N-carbamoylputrescine	biological_process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.
GO:0033391	chromatoid body	cellular_component	A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
GO:0033393	homogalacturonan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
GO:0033394	beta-alanine biosynthetic process via 1,3 diaminopropane	biological_process	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.
GO:0033395	beta-alanine biosynthetic process via 3-hydroxypropionate	biological_process	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.
GO:0033396	beta-alanine biosynthetic process via 3-ureidopropionate	biological_process	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.
GO:0033397	zeatin metabolic process	biological_process	The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033398	zeatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033399	cis-zeatin metabolic process	biological_process	The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033400	trans-zeatin metabolic process	biological_process	The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033401	UUU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UUU codon.
GO:0033402	UUC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UUC codon.
GO:0033403	UUA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UUA codon.
GO:0033404	UUG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UUG codon.
GO:0033405	UCU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UCU codon.
GO:0033406	UCC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UCC codon.
GO:0033407	UCA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UCA codon.
GO:0033408	UCG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UCG codon.
GO:0033409	UAU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UAU codon.
GO:0033410	UAC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UAC codon.
GO:0033411	UAA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UAA codon.
GO:0033412	UAG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UAG codon.
GO:0033413	UGU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UGU codon.
GO:0033414	UGC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UGC codon.
GO:0033415	UGA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UGA codon.
GO:0033416	UGG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a UGG codon.
GO:0033417	CUU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CUU codon.
GO:0033418	CUC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CUC codon.
GO:0033419	CUA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CUA codon.
GO:0033420	CUG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CUG codon.
GO:0033421	CCU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CCU codon.
GO:0033422	CCC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CCC codon.
GO:0033423	CCA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CCA codon.
GO:0033424	CCG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CCG codon.
GO:0033425	CAU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CAU codon.
GO:0033426	CAC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CAC codon.
GO:0033427	CAA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CAA codon.
GO:0033428	CAG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CAG codon.
GO:0033429	CGU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CGU codon.
GO:0033430	CGC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CGC codon.
GO:0033431	CGA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CGA codon.
GO:0033432	CGG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a CGG codon.
GO:0033433	AUU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AUU codon.
GO:0033434	AUC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AUC codon.
GO:0033435	AUA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AUA codon.
GO:0033436	AUG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AUG codon.
GO:0033437	ACU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an ACU codon.
GO:0033438	ACC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an ACC codon.
GO:0033439	ACA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an ACA codon.
GO:0033440	ACG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an ACG codon.
GO:0033441	AAU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AAU codon.
GO:0033442	AAC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AAC codon.
GO:0033443	AAA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AAA codon.
GO:0033444	AAG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AAG codon.
GO:0033445	AGU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AGU codon.
GO:0033446	AGC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AGC codon.
GO:0033447	AGA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AGA codon.
GO:0033448	AGG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes an AGG codon.
GO:0033449	GUU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GUU codon.
GO:0033450	GUC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GUC codon.
GO:0033451	GUA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GUA codon.
GO:0033452	GUG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GUG codon.
GO:0033453	GCU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GCU codon.
GO:0033454	GCC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GCC codon.
GO:0033455	GCA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GCA codon.
GO:0033456	GCG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GCG codon.
GO:0033457	GAU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GAU codon.
GO:0033458	GAC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GAC codon.
GO:0033459	GAA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GAA codon.
GO:0033460	GAG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GAG codon.
GO:0033461	GGU codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GGU codon.
GO:0033462	GGC codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GGC codon.
GO:0033463	GGA codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GGA codon.
GO:0033464	GGG codon-amino acid adaptor activity	molecular_function	A triplet codon-amino acid adaptor activity that recognizes a GGG codon.
GO:0033465	cis-zeatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033466	trans-zeatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
GO:0033467	CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process	biological_process	The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.
GO:0033468	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.
GO:0033469	gibberellin 12 metabolic process	biological_process	The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.
GO:0033470	gibberellin 12 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.
GO:0033471	GDP-L-galactose metabolic process	biological_process	The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.
GO:0033472	GDP-L-galactose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.
GO:0033473	indoleacetic acid conjugate metabolic process	biological_process	The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.
GO:0033474	indoleacetic acid conjugate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.
GO:0033475	indoleacetic acid amide conjugate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.
GO:0033476	indoleacetic acid ester conjugate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.
GO:0033477	S-methylmethionine metabolic process	biological_process	The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.
GO:0033478	UDP-rhamnose metabolic process	biological_process	The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.
GO:0033479	UDP-D-galacturonate metabolic process	biological_process	The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.
GO:0033480	UDP-D-galacturonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.
GO:0033481	galacturonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.
GO:0033482	D-galacturonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
GO:0033484	intracellular nitric oxide homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell.
GO:0033485	cyanidin 3-O-glucoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.
GO:0033486	delphinidin 3-O-glucoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.
GO:0033487	pelargonidin 3-O-glucoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.
GO:0033488	cholesterol biosynthetic process via 24,25-dihydrolanosterol	biological_process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.
GO:0033489	cholesterol biosynthetic process via desmosterol	biological_process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.
GO:0033490	cholesterol biosynthetic process via lathosterol	biological_process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
GO:0033491	coniferin metabolic process	biological_process	The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.
GO:0033492	esculetin metabolic process	biological_process	The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin.
GO:0033493	esculetin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.
GO:0033494	ferulate metabolic process	biological_process	The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.
GO:0033495	ferulate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.
GO:0033496	sinapate metabolic process	biological_process	The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
GO:0033497	sinapate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
GO:0033498	galactose catabolic process via D-galactonate	biological_process	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.
GO:0033499	galactose catabolic process via UDP-galactose	biological_process	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.
GO:0033500	carbohydrate homeostasis	biological_process	A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.
GO:0033503	HULC complex	cellular_component	A ubiquitin ligase complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp6, Shf1, Brl2/Rfp1 and Brl1/Rfp2.
GO:0033504	floor plate development	biological_process	The progression of the floor plate over time from its initial formation until its mature state.
GO:0033505	floor plate morphogenesis	biological_process	The process in which the anatomical structure of the floor plate is generated and organized.
GO:0033506	glucosinolate biosynthetic process from homomethionine	biological_process	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.
GO:0033507	glucosinolate biosynthetic process from phenylalanine	biological_process	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.
GO:0033508	glutamate catabolic process to butyrate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.
GO:0033509	glutamate catabolic process to propionate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.
GO:0033510	luteolin metabolic process	biological_process	The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.
GO:0033511	luteolin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.
GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.
GO:0033513	L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.
GO:0033514	L-lysine catabolic process to acetyl-CoA via L-pipecolate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.
GO:0033515	L-lysine catabolic process using lysine 6-aminotransferase	biological_process	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.
GO:0033516	L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.
GO:0033517	myo-inositol hexakisphosphate metabolic process	biological_process	The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
GO:0033519	phytyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.
GO:0033520	phytol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
GO:0033521	phytyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.
GO:0033522	histone H2A ubiquitination	biological_process	The modification of histone H2A by addition of one or more ubiquitin groups.
GO:0033523	histone H2B ubiquitination	biological_process	The modification of histone H2B by addition of ubiquitin groups.
GO:0033524	sinapate ester metabolic process	biological_process	The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
GO:0033525	sinapate ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
GO:0033526	tetrapyrrole biosynthetic process from glutamate	biological_process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.
GO:0033527	tetrapyrrole biosynthetic process from glycine and succinyl-CoA	biological_process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.
GO:0033528	S-methylmethionine cycle	biological_process	A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.
GO:0033529	raffinose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033530	raffinose metabolic process	biological_process	The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033531	stachyose metabolic process	biological_process	The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033532	stachyose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033533	verbascose metabolic process	biological_process	The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033534	verbascose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033535	ajugose metabolic process	biological_process	The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033536	ajugose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0033537	ajugose biosynthetic process using galactinol:raffinose galactosyltransferase	biological_process	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.
GO:0033538	ajugose biosynthetic process using galactan:galactan galactosyltransferase	biological_process	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	biological_process	A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	biological_process	A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033541	fatty acid beta-oxidation, unsaturated, odd number	biological_process	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033542	fatty acid beta-oxidation, unsaturated, even number	biological_process	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033543	fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway	biological_process	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033544	fatty acid beta-oxidation, unsaturated, even number, epimerase pathway	biological_process	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0033545	myo-inositol hexakisphosphate biosynthetic process, lipid-dependent	biological_process	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.
GO:0033546	myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate	biological_process	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.
GO:0033548	myo-inositol hexakisphosphate biosynthetic process, lipid-independent	biological_process	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.
GO:0033549	MAP kinase phosphatase activity	molecular_function	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.
GO:0033550	MAP kinase tyrosine phosphatase activity	molecular_function	Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.
GO:0033551	monopolin complex	cellular_component	A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.
GO:0033552	response to vitamin B3	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.
GO:0033553	rDNA heterochromatin	cellular_component	A region of heterochromatin located at the rDNA repeats in a chromosome.
GO:0033554	cellular response to stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0033555	multicellular organismal response to stress	biological_process	Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0033556	dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity	molecular_function	Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.
GO:0033557	Slx1-Slx4 complex	cellular_component	A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.
GO:0033558	protein lysine deacetylase activity	molecular_function	Catalysis of the reaction: H2O + N6-acetyl-L-lysyl-[protein] = acetate + L-lysyl-[protein].
GO:0033559	unsaturated fatty acid metabolic process	biological_process	The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
GO:0033560	folate reductase activity	molecular_function	Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.
GO:0033562	co-transcriptional gene silencing by RNA interference machinery	biological_process	A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.
GO:0033563	dorsal/ventral axon guidance	biological_process	The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
GO:0033564	anterior/posterior axon guidance	biological_process	The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO:0033565	ESCRT-0 complex	cellular_component	A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.
GO:0033566	gamma-tubulin complex localization	biological_process	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.
GO:0033567	DNA replication, Okazaki fragment processing	biological_process	The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.
GO:0033568	lactoferrin receptor activity	molecular_function	Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.
GO:0033569	lactoferrin transmembrane transporter activity	molecular_function	Enables the transfer of lactoferrin from one side of a membrane to the other.
GO:0033571	lactoferrin transport	biological_process	The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033572	transferrin transport	biological_process	The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0033573	high-affinity iron permease complex	cellular_component	A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0033574	response to testosterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
GO:0033583	rhabdomere membrane	cellular_component	The portion of the plasma membrane surrounding the rhabdomere.
GO:0033584	tyrosine biosynthetic process from chorismate via L-arogenate	biological_process	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.
GO:0033585	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate	biological_process	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.
GO:0033586	L-phenylalanine biosynthetic process from chorismate via L-arogenate	biological_process	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.
GO:0033588	elongator holoenzyme complex	cellular_component	A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA.
GO:0033590	response to cobalamin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.
GO:0033591	response to L-ascorbic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
GO:0033592	RNA strand annealing activity	molecular_function	An activity that facilitates the formation of a complementary double-stranded RNA molecule.
GO:0033593	BRCA2-MAGE-D1 complex	cellular_component	A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.
GO:0033594	response to hydroxyisoflavone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.
GO:0033595	response to genistein	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.
GO:0033596	TSC1-TSC2 complex	cellular_component	A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.
GO:0033597	mitotic checkpoint complex	cellular_component	A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.
GO:0033598	mammary gland epithelial cell proliferation	biological_process	The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
GO:0033599	regulation of mammary gland epithelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	biological_process	Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.
GO:0033602	negative regulation of dopamine secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.
GO:0033603	positive regulation of dopamine secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
GO:0033604	negative regulation of catecholamine secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.
GO:0033605	positive regulation of catecholamine secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.
GO:0033606	chemokine receptor transport within lipid bilayer	biological_process	The directed movement of a chemokine receptor within a lipid bilayer.
GO:0033607	SOD1-Bcl-2 complex	cellular_component	A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.
GO:0033608	formyl-CoA transferase activity	molecular_function	Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.
GO:0033609	oxalate metabolic process	biological_process	The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
GO:0033610	oxalate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.
GO:0033611	oxalate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.
GO:0033612	receptor serine/threonine kinase binding	molecular_function	Binding to a receptor that possesses protein serine/threonine kinase activity.
GO:0033614	chloroplast proton-transporting ATP synthase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
GO:0033616	plasma membrane proton-transporting ATP synthase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.
GO:0033617	mitochondrial cytochrome c oxidase assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
GO:0033618	plasma membrane respiratory chain complex IV assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.
GO:0033619	membrane protein proteolysis	biological_process	The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
GO:0033620	Mei2 nuclear dot complex	cellular_component	A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.
GO:0033621	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	biological_process	The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
GO:0033622	integrin activation	biological_process	The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
GO:0033623	regulation of integrin activation	biological_process	Any process that modulates the frequency, rate, or extent of integrin activation.
GO:0033624	negative regulation of integrin activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.
GO:0033625	positive regulation of integrin activation	biological_process	Any process that activates or increases the frequency, rate, or extent of integrin activation.
GO:0033626	positive regulation of integrin activation by cell surface receptor linked signal transduction	biological_process	Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands.
GO:0033627	cell adhesion mediated by integrin	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
GO:0033628	regulation of cell adhesion mediated by integrin	biological_process	Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
GO:0033629	negative regulation of cell adhesion mediated by integrin	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.
GO:0033630	positive regulation of cell adhesion mediated by integrin	biological_process	Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
GO:0033631	cell-cell adhesion mediated by integrin	biological_process	The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
GO:0033632	regulation of cell-cell adhesion mediated by integrin	biological_process	Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
GO:0033633	negative regulation of cell-cell adhesion mediated by integrin	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	biological_process	Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
GO:0033635	modulation by symbiont of host response to abiotic stimulus	biological_process	Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033638	modulation by symbiont of host heat acclimation	biological_process	Any process in which an organism modulates the host's tolerance to high temperatures, above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033643	host cell part	cellular_component	Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033644	host cell membrane	cellular_component	Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033645	host cell endomembrane system	cellular_component	A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033646	host intracellular part	cellular_component	Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033647	host intracellular organelle	cellular_component	Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033648	host intracellular membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033650	host cell mitochondrion	cellular_component	A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033651	host cell plastid	cellular_component	Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033652	host cell chloroplast	cellular_component	A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033653	host cell chloroplast part	cellular_component	Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033654	host cell chloroplast thylakoid membrane	cellular_component	Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033655	host cell cytoplasm part	cellular_component	Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033656	disruption by symbiont of host chloroplast	biological_process	The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033657	disruption by symbiont of host chloroplast part	biological_process	The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033658	disruption by symbiont of host chloroplast thylakoid	biological_process	The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033659	disruption by symbiont of host mitochondrion	biological_process	The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033660	suppression by symbiont of host resistance gene-dependent defense response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033661	effector-mediated defense to host-produced reactive oxygen species	biological_process	A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033668	suppression by symbiont of host apoptotic process	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0033670	regulation of NAD+ kinase activity	biological_process	Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
GO:0033671	negative regulation of NAD+ kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
GO:0033672	positive regulation of NAD+ kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
GO:0033673	negative regulation of kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0033674	positive regulation of kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0033675	pericanalicular vesicle	cellular_component	A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.
GO:0033677	DNA/RNA helicase activity	molecular_function	Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.
GO:0033678	5'-3' DNA/RNA helicase activity	molecular_function	Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.
GO:0033679	3'-5' DNA/RNA helicase activity	molecular_function	Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.
GO:0033684	regulation of luteinizing hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.
GO:0033685	negative regulation of luteinizing hormone secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.
GO:0033686	positive regulation of luteinizing hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.
GO:0033687	osteoblast proliferation	biological_process	The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
GO:0033688	regulation of osteoblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of osteoblast proliferation.
GO:0033689	negative regulation of osteoblast proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.
GO:0033690	positive regulation of osteoblast proliferation	biological_process	Any process that activates or increases the rate or extent of osteoblast proliferation.
GO:0033691	sialic acid binding	molecular_function	Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
GO:0033693	neurofilament bundle assembly	biological_process	The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.
GO:0033694	oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.
GO:0033696	heterochromatin boundary formation	biological_process	A process that forms a boundary that limits the spreading of heterochromatin along a chromosome.
GO:0033698	Rpd3L complex	cellular_component	A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors.
GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	molecular_function	Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.
GO:0033700	phospholipid efflux	biological_process	The directed movement of a phospholipid out of a cell or organelle.
GO:0033701	dTDP-galactose 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.
GO:0033702	(+)-trans-carveol dehydrogenase activity	molecular_function	Catalysis of the reaction: (1R,5S)-carveol + NAD+ = (S)-carvone + H+ + NADH.
GO:0033703	3beta-hydroxy-5beta-steroid dehydrogenase activity	molecular_function	Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP+ = 5beta-pregnan-3,20-dione + H+ + NADPH.
GO:0033704	3beta-hydroxy-5alpha-steroid dehydrogenase activity	molecular_function	Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5alpha-pregnane-3,20-dione + H+ + NADPH.
GO:0033705	GDP-4-dehydro-6-deoxy-D-mannose reductase activity	molecular_function	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.
GO:0033707	3''-deamino-3''-oxonicotianamine reductase activity	molecular_function	Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.
GO:0033708	isocitrate-homoisocitrate dehydrogenase activity	molecular_function	Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.
GO:0033709	D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity	molecular_function	Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.
GO:0033711	4-phosphoerythronate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-phospho-D-erythronate + NAD+ = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H+ + NADH.
GO:0033712	1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity	molecular_function	Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.
GO:0033713	choline:oxygen 1-oxidoreductase activity	molecular_function	Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide.
GO:0033714	secondary-alcohol oxidase activity	molecular_function	Catalysis of the reaction: secondary alcohol + O2 = H2O2 + ketone.
GO:0033715	nucleoside oxidase activity	molecular_function	Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.
GO:0033716	nucleoside oxidase (hydrogen peroxide-forming) activity	molecular_function	Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.
GO:0033717	gluconate 2-dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.
GO:0033718	pyranose dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.
GO:0033719	2-oxo-acid reductase activity	molecular_function	Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.
GO:0033720	(S)-mandelate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.
GO:0033721	aldehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
GO:0033722	malonate-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.
GO:0033723	fluoroacetaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.
GO:0033726	aldehyde ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.
GO:0033727	aldehyde dehydrogenase (FAD-independent) activity	molecular_function	Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.
GO:0033728	divinyl chlorophyllide a 8-vinyl-reductase activity	molecular_function	Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.
GO:0033729	anthocyanidin reductase activity	molecular_function	Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.
GO:0033730	arogenate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.
GO:0033731	arogenate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.
GO:0033732	pyrroloquinoline-quinone synthase activity	molecular_function	Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 2 H2O + 2 H2O2 + H+ + pyrroloquinoline quinone.
GO:0033734	(R)-benzylsuccinyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.
GO:0033735	aspartate dehydrogenase activity	molecular_function	Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+.
GO:0033736	L-lysine 6-oxidase activity	molecular_function	Catalysis of the reaction: L-lysine + H2O + O2 = allysine + H2O2 + NH4.
GO:0033737	1-pyrroline dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
GO:0033738	methylenetetrahydrofolate reductase (ferredoxin) activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.
GO:0033739	preQ1 synthase activity	molecular_function	Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH.
GO:0033740	hydroxylamine oxidoreductase activity	molecular_function	Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.
GO:0033741	adenylyl-sulfate reductase (glutathione) activity	molecular_function	Catalysis of the reaction: AMP + glutathione disulfide + H+ + sulfite = 5'-adenylyl sulfate + 2 glutathione.
GO:0033743	peptide-methionine (R)-S-oxide reductase activity	molecular_function	Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0033744	L-methionine:thioredoxin-disulfide S-oxidoreductase activity	molecular_function	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.
GO:0033745	L-methionine-(R)-S-oxide reductase activity	molecular_function	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.
GO:0033746	histone H3R2 demethylase activity	molecular_function	Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0033748	hydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: H2 + A = AH2.
GO:0033749	histone H4R3 demethylase activity	molecular_function	Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0033750	ribosome localization	biological_process	A process in which a ribosome is transported to, and/or maintained in, a specific location.
GO:0033752	acetylacetone-cleaving enzyme activity	molecular_function	Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.
GO:0033754	indoleamine 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.
GO:0033755	sulfur oxygenase/reductase activity	molecular_function	Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.
GO:0033756	Oplophorus-luciferin 2-monooxygenase activity	molecular_function	Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.
GO:0033757	glucoside 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.
GO:0033758	clavaminate synthase activity	molecular_function	Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.
GO:0033759	flavone synthase activity	molecular_function	Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.
GO:0033760	2'-deoxymugineic-acid 2'-dioxygenase activity	molecular_function	Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + H+ + mugineate + succinate.
GO:0033761	mugineic-acid 3-dioxygenase activity	molecular_function	Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.
GO:0033762	response to glucagon	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
GO:0033763	proline 3-hydroxylase activity	molecular_function	Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.
GO:0033766	2-hydroxyquinoline 8-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + quinolin-2-ol = H2O + NAD+ + quinoline-2,8-diol.
GO:0033767	4-hydroxyacetophenone monooxygenase activity	molecular_function	Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.
GO:0033768	SUMO-targeted ubiquitin ligase complex	cellular_component	A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.
GO:0033769	glyceollin synthase activity	molecular_function	Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin II or glyceollin III + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin I + NADP+ + 2 H2O.
GO:0033770	2-hydroxyisoflavanone synthase activity	molecular_function	Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase].
GO:0033771	licodione synthase activity	molecular_function	Catalysis of the reaction: H+ + liquiritigenin + NADPH + O2 = H2O + licodione + NADP+.
GO:0033772	flavonoid 3',5'-hydroxylase activity	molecular_function	Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.
GO:0033773	isoflavone 2'-hydroxylase activity	molecular_function	Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
GO:0033774	basal labyrinth	cellular_component	A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.
GO:0033775	deoxysarpagine hydroxylase activity	molecular_function	Catalysis of the reaction: 10-deoxysarpagine + H+ + NADPH + O2 = H2O + NADP+ + sarpagine.
GO:0033776	phenylacetone monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP+.
GO:0033777	lithocholate 6beta-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.
GO:0033778	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+.
GO:0033779	5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H+ + NADPH + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H2O + NADP+.
GO:0033780	taurochenodeoxycholate 6alpha-hydroxylase activity	molecular_function	Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.
GO:0033781	cholesterol 24-hydroxylase activity	molecular_function	Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.
GO:0033782	24-hydroxycholesterol 7alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
GO:0033783	25-hydroxycholesterol 7alpha-hydroxylase activity	molecular_function	Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.
GO:0033784	senecionine N-oxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + senecionine = H2O + NADP+ + senecionine N-oxide.
GO:0033785	heptose 7-phosphate kinase activity	molecular_function	Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.
GO:0033786	heptose-1-phosphate adenylyltransferase activity	molecular_function	Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.
GO:0033787	cyanocobalamin reductase (cyanide-eliminating) activity	molecular_function	Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP+ = cyanocob(III)alamin + H+ + NADPH.
GO:0033788	leucoanthocyanidin reductase activity	molecular_function	Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.
GO:0033789	phenylacetyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2 1,4-benzoquinone + H2O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.
GO:0033790	hydroxymethylfurfural reductase activity	molecular_function	Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.
GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	molecular_function	Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.
GO:0033792	3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity	molecular_function	Catalysis of the reactions: a 3alpha-hydroxy bile acid CoA + NAD+ = a 3-oxo bile acid CoA + H+ + NADH.
GO:0033793	aureusidin synthase activity	molecular_function	Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.
GO:0033794	sarcosine reductase activity	molecular_function	Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.
GO:0033795	betaine reductase activity	molecular_function	Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.
GO:0033796	sulfur reductase activity	molecular_function	Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide.
GO:0033797	selenate reductase activity	molecular_function	Catalysis of the reaction: 2 e(-) + 2 H+ + selenate = H2O + selenite.
GO:0033798	thyroxine 5-deiodinase activity	molecular_function	Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2.
GO:0033799	myricetin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.
GO:0033800	isoflavone 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.
GO:0033801	vitexin 2''-O-rhamnoside 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.
GO:0033802	isoliquiritigenin 2'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H+.
GO:0033803	kaempferol 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H+ + kaempferide.
GO:0033806	fluorothreonine transaldolase activity	molecular_function	Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.
GO:0033807	icosanoyl-CoA synthase activity	molecular_function	Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.
GO:0033808	6'-deoxychalcone synthase activity	molecular_function	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.
GO:0033809	anthocyanin 6''-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).
GO:0033810	anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.
GO:0033811	flavonol-3-O-triglucoside O-coumaroyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].
GO:0033812	3-oxoadipyl-CoA thiolase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.
GO:0033813	deacetylcephalosporin-C acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.
GO:0033814	propanoyl-CoA C-acyltransferase activity	molecular_function	Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
GO:0033815	biphenyl synthase activity	molecular_function	Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.
GO:0033816	diaminobutyrate acetyltransferase activity	molecular_function	Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H+.
GO:0033818	beta-ketoacyl-acyl-carrier-protein synthase III activity	molecular_function	Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.
GO:0033819	lipoyl(octanoyl) transferase activity	molecular_function	Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].
GO:0033820	DNA alpha-glucosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.
GO:0033821	DNA beta-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.
GO:0033822	glucosyl-DNA beta-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.
GO:0033823	procollagen glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.
GO:0033824	alternansucrase activity	molecular_function	Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.
GO:0033825	oligosaccharide 4-alpha-D-glucosyltransferase activity	molecular_function	Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.
GO:0033826	xyloglucan 4-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.
GO:0033827	high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.
GO:0033828	glucosylglycerol-phosphate synthase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H+.
GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.
GO:0033830	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.
GO:0033831	kojibiose phosphorylase activity	molecular_function	Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.
GO:0033832	alpha,alpha-trehalose phosphorylase (configuration-retaining) activity	molecular_function	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.
GO:0033833	hydroxymethylfurfural reductase (NADH) activity	molecular_function	Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.
GO:0033834	kaempferol 3-O-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.
GO:0033835	flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].
GO:0033836	flavonol 7-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.
GO:0033837	anthocyanin 3'-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.
GO:0033838	flavonol-3-O-glucoside glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.
GO:0033839	flavonol-3-O-glycoside glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.
GO:0033840	NDP-glucose-starch glucosyltransferase activity	molecular_function	Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1.
GO:0033841	6G-fructosyltransferase activity	molecular_function	Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).
GO:0033842	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.
GO:0033843	xyloglucan 6-xylosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.
GO:0033844	galactose-6-sulfurylase activity	molecular_function	Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.
GO:0033845	hydroxymethylfurfural reductase (NADPH) activity	molecular_function	Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.
GO:0033846	adenosyl-fluoride synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.
GO:0033847	O-phosphoserine sulfhydrylase activity	molecular_function	Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.
GO:0033848	N2-(2-carboxyethyl)arginine synthase activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H+ + phosphate.
GO:0033849	chrysanthemyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.
GO:0033850	Z-farnesyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.
GO:0033851	lavandulyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.
GO:0033852	thyroid-hormone transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.
GO:0033853	aspartate-prephenate aminotransferase activity	molecular_function	Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate.
GO:0033854	glutamate-prephenate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.
GO:0033855	nicotianamine aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.
GO:0033856	pyridoxine 5'-phosphate synthase activity	molecular_function	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H2O + H+ + phosphate + pyridoxine 5'-phosphate.
GO:0033857	diphosphoinositol-pentakisphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
GO:0033858	N-acetylgalactosamine kinase activity	molecular_function	Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.
GO:0033859	furaldehyde metabolic process	biological_process	The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.
GO:0033860	regulation of NAD(P)H oxidase activity	biological_process	Any process that modulates the activity of the enzyme NAD(P)H oxidase.
GO:0033861	negative regulation of NAD(P)H oxidase activity	biological_process	Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.
GO:0033862	UMP kinase activity	molecular_function	Catalysis of the reaction: ATP + UMP = ADP + UDP.
GO:0033863	ribose 1,5-bisphosphate phosphokinase activity	molecular_function	Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H+.
GO:0033864	positive regulation of NAD(P)H oxidase activity	biological_process	Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.
GO:0033865	nucleoside bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0033866	nucleoside bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0033867	Fas-activated serine/threonine kinase activity	molecular_function	Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.
GO:0033869	nucleoside bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0033870	thiol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.
GO:0033871	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.
GO:0033872	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.
GO:0033873	petromyzonol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H+.
GO:0033874	scymnol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H+.
GO:0033875	ribonucleoside bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0033876	glycochenodeoxycholate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H+.
GO:0033877	succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity	molecular_function	Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.
GO:0033878	hormone-sensitive lipase activity	molecular_function	Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.
GO:0033879	acetylajmaline esterase activity	molecular_function	Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.
GO:0033880	phenylacetyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + phenylglyoxylyl-CoA = CoA + H+ + phenylglyoxylate.
GO:0033881	bile-acid-CoA transferase activity	molecular_function	Catalysis of the reaction: deoxycholoyl-CoA + cholate = deoxycholate + choloyl-CoA.
GO:0033882	choloyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.
GO:0033883	pyridoxal phosphatase activity	molecular_function	Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.
GO:0033885	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity	molecular_function	Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.
GO:0033886	cellulose-polysulfatase activity	molecular_function	Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.
GO:0033887	chondro-4-sulfatase activity	molecular_function	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.
GO:0033888	chondro-6-sulfatase activity	molecular_function	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.
GO:0033889	N-sulfoglucosamine-3-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.
GO:0033890	ribonuclease D activity	molecular_function	Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
GO:0033891	CC-preferring endodeoxyribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.
GO:0033892	deoxyribonuclease (pyrimidine dimer) activity	molecular_function	Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate.
GO:0033893	ribonuclease IV activity	molecular_function	Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
GO:0033894	ribonuclease P4 activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.
GO:0033895	ribonuclease [poly-(U)-specific] activity	molecular_function	Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
GO:0033896	ribonuclease IX activity	molecular_function	Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
GO:0033897	ribonuclease T2 activity	molecular_function	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
GO:0033898	Bacillus subtilis ribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides.
GO:0033899	ribonuclease U2 activity	molecular_function	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.
GO:0033900	ribonuclease F activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.
GO:0033901	ribonuclease V activity	molecular_function	Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.
GO:0033902	rRNA endonuclease activity	molecular_function	Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.
GO:0033904	dextranase activity	molecular_function	Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.
GO:0033905	xylan endo-1,3-beta-xylosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.
GO:0033906	hyaluronoglucuronidase activity	molecular_function	Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.
GO:0033907	beta-D-fucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.
GO:0033908	beta-L-rhamnosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.
GO:0033909	fucoidanase activity	molecular_function	Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.
GO:0033910	glucan 1,4-alpha-maltotetraohydrolase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.
GO:0033911	mycodextranase activity	molecular_function	Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.
GO:0033912	2,6-beta-fructan 6-levanbiohydrolase activity	molecular_function	Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.
GO:0033913	glucan endo-1,2-beta-glucosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.
GO:0033914	xylan 1,3-beta-xylosidase activity	molecular_function	Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.
GO:0033915	mannan 1,2-(1,3)-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.
GO:0033916	beta-agarase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.
GO:0033917	exo-poly-alpha-galacturonosidase activity	molecular_function	Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.
GO:0033918	kappa-carrageenase activity	molecular_function	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.
GO:0033919	glucan 1,3-alpha-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.
GO:0033920	6-phospho-beta-galactosidase activity	molecular_function	Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.
GO:0033921	capsular-polysaccharide endo-1,3-alpha-galactosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.
GO:0033922	peptidoglycan beta-N-acetylmuramidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.
GO:0033923	glucan 1,6-alpha-isomaltosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.
GO:0033924	dextran 1,6-alpha-isomaltotriosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.
GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	molecular_function	Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.
GO:0033926	glycopeptide alpha-N-acetylgalactosaminidase activity	molecular_function	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins.
GO:0033927	glucan 1,4-alpha-maltohexaosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.
GO:0033928	mannan 1,4-mannobiosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.
GO:0033929	blood-group-substance endo-1,4-beta-galactosidase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.
GO:0033930	keratan-sulfate endo-1,4-beta-galactosidase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.
GO:0033931	endogalactosaminidase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).
GO:0033932	1,3-alpha-L-fucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.
GO:0033933	branched-dextran exo-1,2-alpha-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.
GO:0033934	glucan 1,4-alpha-maltotriohydrolase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.
GO:0033935	oligoxyloglucan beta-glycosidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.
GO:0033936	polymannuronate hydrolase activity	molecular_function	Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.
GO:0033937	3-deoxy-2-octulosonidase activity	molecular_function	Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.
GO:0033938	1,6-alpha-L-fucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.
GO:0033939	xylan alpha-1,2-glucuronosidase activity	molecular_function	Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.
GO:0033940	glucuronoarabinoxylan endo-1,4-beta-xylanase activity	molecular_function	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.
GO:0033941	mannan exo-1,2-1,6-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.
GO:0033942	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity	molecular_function	Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.
GO:0033943	galactan 1,3-beta-galactosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.
GO:0033944	beta-galactofuranosidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.
GO:0033945	oligoxyloglucan reducing-end-specific cellobiohydrolase activity	molecular_function	Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
GO:0033946	xyloglucan-specific endo-beta-1,4-glucanase activity	molecular_function	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.
GO:0033947	mannosylglycoprotein endo-beta-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.
GO:0033948	fructan beta-(2,1)-fructosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.
GO:0033949	fructan beta-(2,6)-fructosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.
GO:0033950	xyloglucan-specific exo-beta-1,4-glucanase activity	molecular_function	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.
GO:0033951	oligosaccharide reducing-end xylanase activity	molecular_function	Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.
GO:0033952	iota-carrageenase activity	molecular_function	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.
GO:0033953	alpha-agarase activity	molecular_function	Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.
GO:0033954	alpha-neoagaro-oligosaccharide hydrolase activity	molecular_function	Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.
GO:0033956	beta-apiosyl-beta-glucosidase activity	molecular_function	Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.
GO:0033957	lambda-carrageenase activity	molecular_function	Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.
GO:0033958	DNA-deoxyinosine glycosylase activity	molecular_function	Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine.
GO:0033959	deoxyribodipyrimidine endonucleosidase activity	molecular_function	Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.
GO:0033960	N-methyl nucleosidase activity	molecular_function	Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.
GO:0033961	cis-stilbene-oxide hydrolase activity	molecular_function	Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.
GO:0033962	P-body assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
GO:0033963	cholesterol-5,6-oxide hydrolase activity	molecular_function	Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.
GO:0033964	glycosphingolipid deacylase activity	molecular_function	Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.
GO:0033965	aculeacin-A deacylase activity	molecular_function	Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.
GO:0033966	N-substituted formamide deformylase activity	molecular_function	Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.
GO:0033967	box C/D RNA metabolic process	biological_process	The chemical reactions and pathways involving box C/D type small nucleolar RNA.
GO:0033968	glutaryl-7-aminocephalosporanic-acid acylase activity	molecular_function	Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.
GO:0033969	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	molecular_function	Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate.
GO:0033970	N-malonylurea hydrolase activity	molecular_function	Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H2O = H+ + malonate + urea.
GO:0033971	hydroxyisourate hydrolase activity	molecular_function	Catalysis of the reaction: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+.
GO:0033972	proclavaminate amidinohydrolase activity	molecular_function	Catalysis of the reaction: amidinoproclavaminate + H2O = proclavaminate + urea.
GO:0033973	dCTP deaminase (dUMP-forming) activity	molecular_function	Catalysis of the reaction: dCTP + 2 H2O = diphosphate + dUMP + H+ + NH4.
GO:0033974	nucleoside phosphoacylhydrolase activity	molecular_function	Catalysis of the hydrolysis of mixed phospho-anhydride bonds.
GO:0033975	(R)-2-haloacid dehalogenase activity	molecular_function	Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.
GO:0033976	2-haloacid dehalogenase (configuration-inverting) activity	molecular_function	Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.
GO:0033977	2-haloacid dehalogenase (configuration-retaining) activity	molecular_function	Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.
GO:0033978	phosphonopyruvate hydrolase activity	molecular_function	Catalysis of the reaction: 3-phosphonopyruvate + H2O = phosphate + pyruvate.
GO:0033979	box H/ACA RNA metabolic process	biological_process	The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.
GO:0033980	phosphonopyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-phosphonopyruvate + 2 H+ = CO2 + phosphonoacetaldehyde.
GO:0033981	D-dopachrome decarboxylase activity	molecular_function	Catalysis of the reaction: D-dopachrome + H+ = 5,6-dihydroxyindole + CO2.
GO:0033982	3-dehydro-L-gulonate-6-phosphate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2.
GO:0033983	diaminobutyrate decarboxylase activity	molecular_function	Catalysis of the reaction: L-2,4-diaminobutyrate + H+ = 1,3-diaminopropane + CO2.
GO:0033984	indole-3-glycerol-phosphate lyase activity	molecular_function	Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.
GO:0033985	acidocalcisome lumen	cellular_component	The volume enclosed by the membranes of an acidocalcisome.
GO:0033986	response to methanol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.
GO:0033987	2-hydroxyisoflavanone dehydratase activity	molecular_function	Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O.
GO:0033988	bile-acid 7alpha-dehydratase activity	molecular_function	Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O.
GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.
GO:0033990	ectoine synthase activity	molecular_function	Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H2O.
GO:0033991	aldos-2-ulose dehydratase activity	molecular_function	Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.
GO:0033992	1,5-anhydro-D-fructose dehydratase activity	molecular_function	Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.
GO:0033993	response to lipid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
GO:0033994	glucuronan lyase activity	molecular_function	Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.
GO:0033995	anhydrosialidase activity	molecular_function	Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.
GO:0033996	levan fructotransferase (DFA-IV-forming) activity	molecular_function	Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
GO:0033997	inulin fructotransferase (DFA-I-forming) activity	molecular_function	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
GO:0033998	inulin fructotransferase (DFA-III-forming) activity	molecular_function	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
GO:0033999	chondroitin B lyase activity	molecular_function	Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.
GO:0034000	chondroitin-sulfate-ABC endolyase activity	molecular_function	Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.
GO:0034001	chondroitin-sulfate-ABC exolyase activity	molecular_function	Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.
GO:0034002	(R)-limonene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate.
GO:0034003	vetispiradiene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.
GO:0034004	germacradienol synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.
GO:0034005	germacrene-A synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
GO:0034006	amorpha-4,11-diene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.
GO:0034007	S-linalool synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + H2O = (S)-linalool + diphosphate.
GO:0034008	R-linalool synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + H2O = (R)-linalool + diphosphate.
GO:0034009	isoprene synthase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.
GO:0034010	sulfolactate sulfo-lyase activity	molecular_function	Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.
GO:0034011	L-cysteate sulfo-lyase activity	molecular_function	Catalysis of the reaction: L-cysteate + H2O = NH4 + pyruvate + sulfite.
GO:0034012	FAD-AMP lyase (cyclizing) activity	molecular_function	Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.
GO:0034013	aliphatic aldoxime dehydratase activity	molecular_function	Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.
GO:0034014	response to triglyceride	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.
GO:0034015	L-ribulose-5-phosphate 3-epimerase activity	molecular_function	Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.
GO:0034016	polyenoic fatty acid isomerase activity	molecular_function	Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.
GO:0034017	trans-2-decenoyl-acyl-carrier-protein isomerase activity	molecular_function	Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].
GO:0034018	ascopyrone tautomerase activity	molecular_function	Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.
GO:0034020	neoxanthin synthase activity	molecular_function	Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.
GO:0034021	response to silicon dioxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.
GO:0034022	3-(hydroxyamino)phenol mutase activity	molecular_function	Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.
GO:0034023	5-(carboxyamino)imidazole ribonucleotide mutase activity	molecular_function	Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.
GO:0034024	glutamate-putrescine ligase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H+ + phosphate.
GO:0034025	D-aspartate ligase activity	molecular_function	Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.
GO:0034026	L-amino-acid alpha-ligase activity	molecular_function	Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.
GO:0034027	(carboxyethyl)arginine beta-lactam-synthase activity	molecular_function	Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H+.
GO:0034028	5-(carboxyamino)imidazole ribonucleotide synthase activity	molecular_function	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H+ + phosphate.
GO:0034029	2-oxoglutarate carboxylase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H+ + oxalosuccinate + phosphate.
GO:0034030	ribonucleoside bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034031	ribonucleoside bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034032	purine nucleoside bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034033	purine nucleoside bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034034	purine nucleoside bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034035	purine ribonucleoside bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034036	purine ribonucleoside bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034037	purine ribonucleoside bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
GO:0034038	deoxyhypusine synthase activity	molecular_function	Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.
GO:0034039	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	molecular_function	Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.
GO:0034040	ATPase-coupled lipid transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).
GO:0034041	ABC-type sterol transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).
GO:0034042	5-formyluracil DNA N-glycosylase activity	molecular_function	Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
GO:0034043	5-hydroxymethyluracil DNA N-glycosylase activity	molecular_function	Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
GO:0034044	exomer complex	cellular_component	A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.
GO:0034045	phagophore assembly site membrane	cellular_component	A cellular membrane associated with the phagophore assembly site.
GO:0034046	poly(G) binding	molecular_function	Binding to a sequence of guanine residues in an RNA molecule.
GO:0034050	programmed cell death induced by symbiont	biological_process	Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.
GO:0034051	negative regulation of plant-type hypersensitive response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.
GO:0034052	positive regulation of plant-type hypersensitive response	biological_process	Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.
GO:0034053	modulation by symbiont of host defense-related programmed cell death	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0034054	suppression by symbiont of host defense-related programmed cell death	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0034055	effector-mediated induction of programmed cell death in host	biological_process	A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0034056	estrogen response element binding	molecular_function	Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
GO:0034057	RNA strand-exchange activity	molecular_function	Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.
GO:0034058	endosomal vesicle fusion	biological_process	The homotypic fusion of endocytic vesicles to form or add to an early endosome.
GO:0034059	response to anoxia	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
GO:0034060	cyanelle stroma	cellular_component	The space enclosed by the double membrane of a cyanelle.
GO:0034061	DNA polymerase activity	molecular_function	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.
GO:0034062	5'-3' RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.
GO:0034063	stress granule assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
GO:0034064	Tor2-Mei2-Ste11 complex	cellular_component	A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.
GO:0034066	Ric1-Rgp1 guanyl-nucleotide exchange factor complex	cellular_component	A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.
GO:0034067	protein localization to Golgi apparatus	biological_process	A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
GO:0034068	aminoglycoside nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.
GO:0034069	aminoglycoside N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.
GO:0034070	aminoglycoside 1-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.
GO:0034071	aminoglycoside phosphotransferase activity	molecular_function	Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.
GO:0034072	squalene cyclase activity	molecular_function	Catalysis of the reaction: squalene = triterpene.
GO:0034073	tetrahymanol cyclase activity	molecular_function	Catalysis of the reaction: squalene = tetrahymanol.
GO:0034074	marneral synthase activity	molecular_function	Catalysis of the reaction: oxidosqualene = marneral.
GO:0034075	arabidiol synthase activity	molecular_function	Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).
GO:0034076	cucurbitadienol synthase activity	molecular_function	Catalysis of the reaction: oxidosqualene = cucurbitadienol.
GO:0034077	butanediol metabolic process	biological_process	The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
GO:0034078	butanediol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
GO:0034079	butanediol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
GO:0034080	CENP-A containing chromatin assembly	biological_process	The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
GO:0034081	polyketide synthase complex	cellular_component	A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
GO:0034082	type II polyketide synthase complex	cellular_component	A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.
GO:0034083	type III polyketide synthase complex	cellular_component	A polyketide synthase complex that consists of two identical ketosynthase polypeptides.
GO:0034084	steryl deacetylase activity	molecular_function	Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.
GO:0034085	establishment of sister chromatid cohesion	biological_process	The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.
GO:0034086	maintenance of sister chromatid cohesion	biological_process	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.
GO:0034087	establishment of mitotic sister chromatid cohesion	biological_process	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
GO:0034088	maintenance of mitotic sister chromatid cohesion	biological_process	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
GO:0034089	establishment of meiotic sister chromatid cohesion	biological_process	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.
GO:0034090	maintenance of meiotic sister chromatid cohesion	biological_process	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
GO:0034091	regulation of maintenance of sister chromatid cohesion	biological_process	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.
GO:0034092	negative regulation of maintenance of sister chromatid cohesion	biological_process	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
GO:0034093	positive regulation of maintenance of sister chromatid cohesion	biological_process	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
GO:0034094	regulation of maintenance of meiotic sister chromatid cohesion	biological_process	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
GO:0034095	negative regulation of maintenance of meiotic sister chromatid cohesion	biological_process	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
GO:0034096	positive regulation of maintenance of meiotic sister chromatid cohesion	biological_process	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
GO:0034097	response to cytokine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	cellular_component	A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).
GO:0034099	luminal surveillance complex	cellular_component	A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.
GO:0034101	erythrocyte homeostasis	biological_process	Any process of regulating the production and elimination of erythrocytes within an organism.
GO:0034102	erythrocyte clearance	biological_process	The selective elimination of erythrocytes from the body by autoregulatory mechanisms.
GO:0034103	regulation of tissue remodeling	biological_process	Any process that modulates the frequency, rate, or extent of tissue remodeling.
GO:0034104	negative regulation of tissue remodeling	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.
GO:0034105	positive regulation of tissue remodeling	biological_process	Any process that activates or increases the frequency, rate, or extent of tissue remodeling.
GO:0034106	regulation of erythrocyte clearance	biological_process	Any process that modulates the frequency, rate, or extent of erythrocyte clearance.
GO:0034107	negative regulation of erythrocyte clearance	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.
GO:0034108	positive regulation of erythrocyte clearance	biological_process	Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.
GO:0034109	homotypic cell-cell adhesion	biological_process	The attachment of a cell to a second cell of the identical type via adhesion molecules.
GO:0034110	regulation of homotypic cell-cell adhesion	biological_process	Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
GO:0034111	negative regulation of homotypic cell-cell adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.
GO:0034112	positive regulation of homotypic cell-cell adhesion	biological_process	Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.
GO:0034113	heterotypic cell-cell adhesion	biological_process	The attachment of a cell to a cell of a different type via adhesion molecules.
GO:0034114	regulation of heterotypic cell-cell adhesion	biological_process	Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.
GO:0034115	negative regulation of heterotypic cell-cell adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.
GO:0034116	positive regulation of heterotypic cell-cell adhesion	biological_process	Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
GO:0034117	erythrocyte aggregation	biological_process	The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.
GO:0034118	regulation of erythrocyte aggregation	biological_process	Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.
GO:0034119	negative regulation of erythrocyte aggregation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.
GO:0034120	positive regulation of erythrocyte aggregation	biological_process	Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.
GO:0034121	regulation of toll-like receptor signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.
GO:0034122	negative regulation of toll-like receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
GO:0034123	positive regulation of toll-like receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.
GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
GO:0034125	negative regulation of MyD88-dependent toll-like receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
GO:0034129	positive regulation of MyD88-independent toll-like receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
GO:0034130	toll-like receptor 1 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 1.
GO:0034131	regulation of toll-like receptor 1 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
GO:0034132	negative regulation of toll-like receptor 1 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
GO:0034133	positive regulation of toll-like receptor 1 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
GO:0034134	toll-like receptor 2 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 2.
GO:0034135	regulation of toll-like receptor 2 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
GO:0034138	toll-like receptor 3 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3.
GO:0034139	regulation of toll-like receptor 3 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
GO:0034142	toll-like receptor 4 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 4.
GO:0034143	regulation of toll-like receptor 4 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
GO:0034146	toll-like receptor 5 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
GO:0034147	regulation of toll-like receptor 5 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
GO:0034149	positive regulation of toll-like receptor 5 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
GO:0034150	toll-like receptor 6 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 6.
GO:0034151	regulation of toll-like receptor 6 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
GO:0034152	negative regulation of toll-like receptor 6 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
GO:0034153	positive regulation of toll-like receptor 6 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
GO:0034154	toll-like receptor 7 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 7.
GO:0034155	regulation of toll-like receptor 7 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
GO:0034156	negative regulation of toll-like receptor 7 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
GO:0034158	toll-like receptor 8 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 8.
GO:0034159	regulation of toll-like receptor 8 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
GO:0034160	negative regulation of toll-like receptor 8 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
GO:0034161	positive regulation of toll-like receptor 8 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
GO:0034162	toll-like receptor 9 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 9.
GO:0034163	regulation of toll-like receptor 9 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
GO:0034164	negative regulation of toll-like receptor 9 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
GO:0034166	toll-like receptor 10 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 10.
GO:0034167	regulation of toll-like receptor 10 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
GO:0034168	negative regulation of toll-like receptor 10 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
GO:0034169	positive regulation of toll-like receptor 10 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
GO:0034170	toll-like receptor 11 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 11.
GO:0034171	regulation of toll-like receptor 11 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
GO:0034172	negative regulation of toll-like receptor 11 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
GO:0034173	positive regulation of toll-like receptor 11 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
GO:0034174	toll-like receptor 12 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 12.
GO:0034175	regulation of toll-like receptor 12 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
GO:0034176	negative regulation of toll-like receptor 12 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
GO:0034177	positive regulation of toll-like receptor 12 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
GO:0034178	toll-like receptor 13 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 13.
GO:0034179	regulation of toll-like receptor 13 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
GO:0034180	negative regulation of toll-like receptor 13 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
GO:0034181	positive regulation of toll-like receptor 13 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
GO:0034182	regulation of maintenance of mitotic sister chromatid cohesion	biological_process	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
GO:0034183	negative regulation of maintenance of mitotic sister chromatid cohesion	biological_process	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion	biological_process	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
GO:0034185	apolipoprotein binding	molecular_function	Binding to an apolipoprotein, the protein component of a lipoprotein complex.
GO:0034186	apolipoprotein A-I binding	molecular_function	Binding to apolipoprotein A-I.
GO:0034188	apolipoprotein A-I receptor activity	molecular_function	Combining with an apolipoprotein A-I receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0034189	very-low-density lipoprotein particle binding	molecular_function	Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.
GO:0034190	apolipoprotein receptor binding	molecular_function	Binding to an apolipoprotein receptor.
GO:0034191	apolipoprotein A-I receptor binding	molecular_function	Binding to an apolipoprotein A-I receptor.
GO:0034192	D-galactonate metabolic process	biological_process	The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid.
GO:0034193	L-galactonate metabolic process	biological_process	The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid.
GO:0034194	D-galactonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.
GO:0034195	L-galactonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.
GO:0034196	acylglycerol transport	biological_process	The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.
GO:0034197	triglyceride transport	biological_process	The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
GO:0034198	cellular response to amino acid starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
GO:0034199	activation of protein kinase A activity	biological_process	Any process that initiates the activity of the inactive enzyme protein kinase A.
GO:0034200	D,D-heptose 1,7-bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.
GO:0034201	response to oleic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.
GO:0034202	glycolipid floppase activity	molecular_function	Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0034203	glycolipid translocation	biological_process	The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
GO:0034204	lipid translocation	biological_process	The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
GO:0034205	amyloid-beta formation	biological_process	The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).
GO:0034206	enhanceosome	cellular_component	A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.
GO:0034211	GTP-dependent protein kinase activity	molecular_function	GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.
GO:0034212	peptide N-acetyltransferase activity	molecular_function	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.
GO:0034213	quinolinate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
GO:0034214	protein hexamerization	biological_process	The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
GO:0034215	thiamine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).
GO:0034216	high-affinity thiamine:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0034217	ascospore wall chitin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
GO:0034218	ascospore wall chitin metabolic process	biological_process	The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
GO:0034219	carbohydrate transmembrane transport	biological_process	The process in which a carbohydrate is transported across a membrane.
GO:0034220	monoatomic ion transmembrane transport	biological_process	A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0034221	fungal-type cell wall chitin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.
GO:0034222	regulation of cell wall chitin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.
GO:0034223	regulation of ascospore wall chitin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.
GO:0034224	cellular response to zinc ion starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.
GO:0034227	tRNA thio-modification	biological_process	The addition a sulfur atom to a nucleotide in a tRNA molecule.
GO:0034228	ethanolamine transmembrane transporter activity	molecular_function	Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
GO:0034229	ethanolamine transport	biological_process	The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
GO:0034230	enkephalin processing	biological_process	The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.
GO:0034231	islet amyloid polypeptide processing	biological_process	The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).
GO:0034232	ascospore wall chitin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
GO:0034233	regulation of cell wall chitin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.
GO:0034234	regulation of ascospore wall chitin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.
GO:0034235	GPI anchor binding	molecular_function	Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
GO:0034236	protein kinase A catalytic subunit binding	molecular_function	Binding to one or both of the catalytic subunits of protein kinase A.
GO:0034237	protein kinase A regulatory subunit binding	molecular_function	Binding to one or both of the regulatory subunits of protein kinase A.
GO:0034238	macrophage fusion	biological_process	The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
GO:0034239	regulation of macrophage fusion	biological_process	Any process that modulates the frequency, rate or extent of macrophage fusion.
GO:0034240	negative regulation of macrophage fusion	biological_process	Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.
GO:0034241	positive regulation of macrophage fusion	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage fusion.
GO:0034242	negative regulation of syncytium formation by plasma membrane fusion	biological_process	Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0034243	regulation of transcription elongation by RNA polymerase II	biological_process	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
GO:0034244	negative regulation of transcription elongation by RNA polymerase II	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
GO:0034245	mitochondrial DNA-directed RNA polymerase complex	cellular_component	A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.
GO:0034246	mitochondrial transcription factor activity	molecular_function	Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase.
GO:0034247	snoRNA splicing	biological_process	The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.
GO:0034248	regulation of amide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
GO:0034249	negative regulation of amide metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
GO:0034250	positive regulation of amide metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
GO:0034251	regulation of amide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
GO:0034252	negative regulation of amide catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
GO:0034253	positive regulation of amide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
GO:0034254	regulation of urea catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.
GO:0034255	regulation of urea metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
GO:0034256	chlorophyll(ide) b reductase activity	molecular_function	Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.
GO:0034257	nicotinamide riboside transmembrane transporter activity	molecular_function	Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.
GO:0034258	nicotinamide riboside transport	biological_process	The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034260	negative regulation of GTPase activity	biological_process	Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
GO:0034263	positive regulation of autophagy in response to ER overload	biological_process	The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.
GO:0034264	isopentenyl adenine metabolic process	biological_process	The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.
GO:0034265	isopentenyl adenine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.
GO:0034266	isopentenyl adenine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.
GO:0034267	discadenine metabolic process	biological_process	The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
GO:0034268	discadenine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
GO:0034269	discadenine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
GO:0034270	Cvt complex	cellular_component	A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p.
GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	cellular_component	A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.
GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	cellular_component	A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.
GO:0034274	Atg12-Atg5-Atg16 complex	cellular_component	A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.
GO:0034275	kynurenic acid metabolic process	biological_process	The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
GO:0034276	kynurenic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
GO:0034277	ent-cassa-12,15-diene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.
GO:0034278	stemar-13-ene synthase activity	molecular_function	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.
GO:0034279	syn-pimara-7,15-diene synthase activity	molecular_function	Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.
GO:0034280	ent-sandaracopimaradiene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.
GO:0034281	ent-isokaurene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.
GO:0034282	ent-pimara-8(14),15-diene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.
GO:0034283	syn-stemod-13(17)-ene synthase activity	molecular_function	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.
GO:0034284	response to monosaccharide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
GO:0034285	response to disaccharide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.
GO:0034286	response to maltose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.
GO:0034287	detection of monosaccharide stimulus	biological_process	The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.
GO:0034288	detection of disaccharide stimulus	biological_process	The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.
GO:0034289	detection of maltose stimulus	biological_process	The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.
GO:0034293	sexual sporulation	biological_process	The formation of spores derived from the products of meiosis.
GO:0034294	sexual spore wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.
GO:0034295	basidiospore formation	biological_process	The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.
GO:0034296	zygospore formation	biological_process	The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.
GO:0034297	oidium formation	biological_process	The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.
GO:0034298	arthrospore formation	biological_process	The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.
GO:0034299	reproductive blastospore formation	biological_process	The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.
GO:0034300	sporangiospore formation	biological_process	The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
GO:0034301	endospore formation	biological_process	The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.
GO:0034302	akinete formation	biological_process	The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.
GO:0034303	myxospore formation	biological_process	The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.
GO:0034304	actinomycete-type spore formation	biological_process	The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.
GO:0034305	regulation of asexual sporulation	biological_process	Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.
GO:0034306	regulation of sexual sporulation	biological_process	Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.
GO:0034307	regulation of ascospore formation	biological_process	Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.
GO:0034308	primary alcohol metabolic process	biological_process	The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
GO:0034309	primary alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
GO:0034310	primary alcohol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
GO:0034311	diol metabolic process	biological_process	The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.
GO:0034312	diol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
GO:0034313	diol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
GO:0034314	Arp2/3 complex-mediated actin nucleation	biological_process	The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	biological_process	Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
GO:0034317	nicotinic acid riboside kinase activity	molecular_function	Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide.
GO:0034318	alcohol O-acyltransferase activity	molecular_function	Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.
GO:0034319	alcohol O-butanoyltransferase activity	molecular_function	Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.
GO:0034320	alcohol O-hexanoyltransferase activity	molecular_function	Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.
GO:0034321	alcohol O-octanoyltransferase activity	molecular_function	Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester.
GO:0034322	alcohol O-decanoyltransferase activity	molecular_function	Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.
GO:0034323	O-butanoyltransferase activity	molecular_function	Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.
GO:0034324	O-hexanoyltransferase activity	molecular_function	Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule.
GO:0034325	O-decanoyltransferase activity	molecular_function	Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule.
GO:0034326	butanoyltransferase activity	molecular_function	Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule.
GO:0034327	hexanoyltransferase activity	molecular_function	Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.
GO:0034328	decanoyltransferase activity	molecular_function	Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.
GO:0034329	cell junction assembly	biological_process	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.
GO:0034330	cell junction organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
GO:0034331	cell junction maintenance	biological_process	The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
GO:0034332	adherens junction organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:0034333	adherens junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:0034334	adherens junction maintenance	biological_process	The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:0034335	DNA negative supercoiling activity	molecular_function	Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.
GO:0034336	misfolded RNA binding	molecular_function	Binding to an RNA molecule that has assumed an incorrect conformation.
GO:0034337	RNA folding	biological_process	The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.
GO:0034338	short-chain carboxylesterase activity	molecular_function	Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.
GO:0034340	response to type I interferon	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0034341	response to type II interferon	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
GO:0034342	response to type III interferon	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.
GO:0034343	type III interferon production	biological_process	The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.
GO:0034344	regulation of type III interferon production	biological_process	Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
GO:0034345	negative regulation of type III interferon production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
GO:0034346	positive regulation of type III interferon production	biological_process	Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
GO:0034347	type III interferon binding	molecular_function	Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.
GO:0034348	type III interferon receptor activity	molecular_function	Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.
GO:0034349	glial cell apoptotic process	biological_process	Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
GO:0034350	regulation of glial cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.
GO:0034351	negative regulation of glial cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.
GO:0034352	positive regulation of glial cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.
GO:0034353	mRNA 5'-diphosphatase activity	molecular_function	Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end.
GO:0034354	'de novo' NAD biosynthetic process from tryptophan	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0034355	NAD salvage	biological_process	Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.
GO:0034357	photosynthetic membrane	cellular_component	A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.
GO:0034358	plasma lipoprotein particle	cellular_component	A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
GO:0034359	mature chylomicron	cellular_component	A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.
GO:0034360	chylomicron remnant	cellular_component	A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.
GO:0034361	very-low-density lipoprotein particle	cellular_component	A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
GO:0034362	low-density lipoprotein particle	cellular_component	A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.
GO:0034363	intermediate-density lipoprotein particle	cellular_component	A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).
GO:0034364	high-density lipoprotein particle	cellular_component	A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
GO:0034365	discoidal high-density lipoprotein particle	cellular_component	A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).
GO:0034366	spherical high-density lipoprotein particle	cellular_component	A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
GO:0034367	protein-containing complex remodeling	biological_process	The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.
GO:0034368	protein-lipid complex remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.
GO:0034369	plasma lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
GO:0034370	triglyceride-rich lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.
GO:0034371	chylomicron remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0034372	very-low-density lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0034373	intermediate-density lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.
GO:0034374	low-density lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
GO:0034375	high-density lipoprotein particle remodeling	biological_process	The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
GO:0034376	conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle	biological_process	The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.
GO:0034377	plasma lipoprotein particle assembly	biological_process	The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.
GO:0034378	chylomicron assembly	biological_process	The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.
GO:0034379	very-low-density lipoprotein particle assembly	biological_process	The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.
GO:0034380	high-density lipoprotein particle assembly	biological_process	The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
GO:0034381	plasma lipoprotein particle clearance	biological_process	The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0034382	chylomicron remnant clearance	biological_process	The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
GO:0034383	low-density lipoprotein particle clearance	biological_process	The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0034384	high-density lipoprotein particle clearance	biological_process	The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0034385	triglyceride-rich plasma lipoprotein particle	cellular_component	A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.
GO:0034386	4-aminobutyrate:2-oxoglutarate transaminase activity	molecular_function	Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
GO:0034387	4-aminobutyrate:pyruvate transaminase activity	molecular_function	Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine.
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	cellular_component	A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.
GO:0034389	lipid droplet organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
GO:0034390	smooth muscle cell apoptotic process	biological_process	Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.
GO:0034391	regulation of smooth muscle cell apoptotic process	biological_process	Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.
GO:0034392	negative regulation of smooth muscle cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.
GO:0034393	positive regulation of smooth muscle cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.
GO:0034394	protein localization to cell surface	biological_process	A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron	biological_process	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.
GO:0034396	negative regulation of transcription from RNA polymerase II promoter in response to iron	biological_process	Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.
GO:0034397	telomere localization	biological_process	Any process in which a telomere is transported to, and/or maintained in, a specific location.
GO:0034398	telomere tethering at nuclear periphery	biological_process	The process in which a telomere is maintained in a specific location at the nuclear periphery.
GO:0034399	nuclear periphery	cellular_component	The portion of the nuclear lumen proximal to the inner nuclear membrane.
GO:0034400	gerontoplast	cellular_component	A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.
GO:0034402	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	biological_process	The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.
GO:0034403	alignment of 3' and 5' splice sites of mRNA	biological_process	Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.
GO:0034404	nucleobase-containing small molecule biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GO:0034405	response to fluid shear stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
GO:0034406	cell wall beta-glucan metabolic process	biological_process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.
GO:0034407	cell wall (1->3)-beta-D-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
GO:0034408	ascospore wall beta-glucan metabolic process	biological_process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
GO:0034409	ascospore wall (1->3)-beta-D-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
GO:0034410	cell wall beta-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.
GO:0034411	cell wall (1->3)-beta-D-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
GO:0034412	ascospore wall beta-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
GO:0034413	ascospore wall (1->3)-beta-D-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
GO:0034417	bisphosphoglycerate 3-phosphatase activity	molecular_function	Catalysis of the reaction: (2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate.
GO:0034418	urate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.
GO:0034420	co-translational protein acetylation	biological_process	The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.
GO:0034421	post-translational protein acetylation	biological_process	The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.
GO:0034422	aleurone grain lumen	cellular_component	The volume enclosed by the membrane of an aleurone grain.
GO:0034423	autophagosome lumen	cellular_component	The volume enclosed within the autophagosome double-membrane.
GO:0034424	Vps55/Vps68 complex	cellular_component	A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.
GO:0034425	etioplast envelope	cellular_component	The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0034426	etioplast membrane	cellular_component	Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.
GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	biological_process	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
GO:0034428	nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'	biological_process	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.
GO:0034429	tectobulbar tract morphogenesis	biological_process	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.
GO:0034430	monolayer-surrounded lipid storage body outer lipid monolayer	cellular_component	The single layer of phopholipids surrounding a lipid storage body.
GO:0034431	bis(5'-adenosyl)-hexaphosphatase activity	molecular_function	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.
GO:0034432	bis(5'-adenosyl)-pentaphosphatase activity	molecular_function	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.
GO:0034436	glycoprotein transport	biological_process	The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034438	lipoprotein amino acid oxidation	biological_process	The modification of a lipoprotein by oxidation of one or more amino acids in the protein.
GO:0034439	lipoprotein lipid oxidation	biological_process	The modification of a lipoprotein by oxidation of the lipid group.
GO:0034440	lipid oxidation	biological_process	The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
GO:0034441	plasma lipoprotein particle oxidation	biological_process	The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids.
GO:0034442	regulation of lipoprotein oxidation	biological_process	Any process that modulates the frequency, rate or extent of lipoprotein oxidation.
GO:0034443	negative regulation of lipoprotein oxidation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.
GO:0034444	regulation of plasma lipoprotein oxidation	biological_process	Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.
GO:0034445	negative regulation of plasma lipoprotein oxidation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.
GO:0034446	substrate adhesion-dependent cell spreading	biological_process	The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
GO:0034447	very-low-density lipoprotein particle clearance	biological_process	The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0034450	ubiquitin-ubiquitin ligase activity	molecular_function	Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
GO:0034451	centriolar satellite	cellular_component	A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.
GO:0034452	dynactin binding	molecular_function	Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity.
GO:0034453	microtubule anchoring	biological_process	Any process in which a microtubule is maintained in a specific location in a cell.
GO:0034454	microtubule anchoring at centrosome	biological_process	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.
GO:0034455	t-UTP complex	cellular_component	A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.
GO:0034456	UTP-C complex	cellular_component	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.
GO:0034457	Mpp10 complex	cellular_component	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.
GO:0034458	3'-5' RNA helicase activity	molecular_function	Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.
GO:0034460	uropod assembly	biological_process	The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.
GO:0034461	uropod retraction	biological_process	The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.
GO:0034462	small-subunit processome assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.
GO:0034463	90S preribosome assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.
GO:0034464	BBSome	cellular_component	A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.
GO:0034465	response to carbon monoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
GO:0034466	chromaffin granule lumen	cellular_component	The volume enclosed by the membrane of a chromaffin granule.
GO:0034467	esterosome lumen	cellular_component	The volume enclosed by the membrane of an esterosome.
GO:0034468	glycosome lumen	cellular_component	The volume enclosed by the membrane of a glycosome.
GO:0034469	Golgi stack lumen	cellular_component	The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.
GO:0034470	ncRNA processing	biological_process	Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.
GO:0034471	ncRNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of a non-coding RNA molecule.
GO:0034472	snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an snRNA molecule.
GO:0034473	U1 snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a U1 snRNA molecule.
GO:0034474	U2 snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a U2 snRNA molecule.
GO:0034475	U4 snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a U4 snRNA molecule.
GO:0034476	U5 snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a U5 snRNA molecule.
GO:0034477	U6 snRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a U6 snRNA molecule.
GO:0034478	phosphatidylglycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.
GO:0034479	phosphatidylglycerol phospholipase C activity	molecular_function	Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.
GO:0034480	phosphatidylcholine phospholipase C activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.
GO:0034481	chondroitin sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.
GO:0034482	chondroitin 2-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.
GO:0034483	heparan sulfate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.
GO:0034484	raffinose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	molecular_function	1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.
GO:0034486	vacuolar transmembrane transport	biological_process	The process in which a solute is transported from one side of the vacuolar membrane to the other.
GO:0034487	vacuolar amino acid transmembrane transport	biological_process	The process in which an amino acid is transported from one side of the vacuolar membrane to the other.
GO:0034488	basic amino acid transmembrane export from vacuole	biological_process	The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.
GO:0034489	neutral amino acid transmembrane export from vacuole	biological_process	The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.
GO:0034490	basic amino acid transmembrane import into vacuole	biological_process	The directed movement of basic amino acids into the vacuole across the vacuolar membrane.
GO:0034491	neutral amino acid transmembrane import into vacuole	biological_process	The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.
GO:0034492	hydrogenosome lumen	cellular_component	The volume enclosed by the hydrogenosome membrane.
GO:0034493	melanosome lumen	cellular_component	The volume enclosed by the melanosome membrane.
GO:0034494	microneme lumen	cellular_component	The volume enclosed by the microneme membrane.
GO:0034495	protein storage vacuole lumen	cellular_component	The volume enclosed by the protein storage vacuole membrane.
GO:0034496	multivesicular body membrane disassembly	biological_process	The controlled breakdown of the membranes of multivesicular bodies.
GO:0034497	protein localization to phagophore assembly site	biological_process	Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).
GO:0034498	early endosome to Golgi transport	biological_process	The directed movement of substances from early endosomes to the Golgi.
GO:0034499	late endosome to Golgi transport	biological_process	The directed movement of substances from late endosomes to the Golgi.
GO:0034501	protein localization to kinetochore	biological_process	Any process in which a protein is transported to, or maintained at, the kinetochore.
GO:0034502	protein localization to chromosome	biological_process	Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
GO:0034503	protein localization to nucleolar rDNA repeats	biological_process	Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.
GO:0034504	protein localization to nucleus	biological_process	A process in which a protein transports or maintains the localization of another protein to the nucleus.
GO:0034505	tooth mineralization	biological_process	The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.
GO:0034506	chromosome, centromeric core domain	cellular_component	The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.
GO:0034508	centromere complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
GO:0034510	centromere separation	biological_process	The cell cycle process in which centromeres are physically detached from each other during chromosome separation.
GO:0034511	U3 snoRNA binding	molecular_function	Binding to a U3 small nucleolar RNA.
GO:0034512	box C/D RNA binding	molecular_function	Binding to a box C/D small nucleolar RNA.
GO:0034513	box H/ACA snoRNA binding	molecular_function	Binding to a box H/ACA small nucleolar RNA.
GO:0034514	mitochondrial unfolded protein response	biological_process	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.
GO:0034515	proteasome storage granule	cellular_component	An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.
GO:0034516	response to vitamin B6	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
GO:0034517	ribophagy	biological_process	The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation.
GO:0034518	RNA cap binding complex	cellular_component	A protein complex that binds to an RNA cap structure to mediate RNA processing and/or translation initiation.
GO:0034520	2-naphthaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+.
GO:0034521	1-naphthoic acid dioxygenase activity	molecular_function	Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.
GO:0034522	cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.
GO:0034523	3-formylsalicylate oxidase activity	molecular_function	Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.
GO:0034524	2-hydroxyisophthalate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2.
GO:0034525	1-naphthaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.
GO:0034526	2-methylnaphthalene hydroxylase activity	molecular_function	Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.
GO:0034527	1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.
GO:0034528	2-carboxy-2-hydroxy-8-carboxychromene isomerase activity	molecular_function	Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.
GO:0034529	2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.
GO:0034530	4-hydroxymethylsalicyaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.
GO:0034531	2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.
GO:0034532	2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.
GO:0034533	1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.
GO:0034534	1-methylnaphthalene hydroxylase activity	molecular_function	Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.
GO:0034535	1,2-dihydroxy-8-methylnaphthalene dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.
GO:0034536	2-hydroxy-8-methylchromene-2-carboxylate isomerase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.
GO:0034537	2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.
GO:0034538	3-methylsalicylaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+.
GO:0034539	3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.
GO:0034540	3-monobromobisphenol A reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr.
GO:0034541	dimethylarsinite methyltransferase activity	molecular_function	Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH.
GO:0034542	trimethylarsine oxidase activity	molecular_function	Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.
GO:0034543	5-aminosalicylate dioxygenase activity	molecular_function	Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate.
GO:0034544	trans-ACOHDA hydrolase activity	molecular_function	Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.
GO:0034545	fumarylpyruvate hydrolase activity	molecular_function	Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.
GO:0034546	2,4-dichloroaniline reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl.
GO:0034547	N-cyclopropylmelamine deaminase activity	molecular_function	Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3.
GO:0034548	N-cyclopropylammeline deaminase activity	molecular_function	Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3.
GO:0034549	N-cyclopropylammelide alkylamino hydrolase activity	molecular_function	Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.
GO:0034550	dimethylarsinate reductase activity	molecular_function	Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.
GO:0034551	mitochondrial respiratory chain complex III assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.
GO:0034552	respiratory chain complex II assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.
GO:0034553	mitochondrial respiratory chain complex II assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.
GO:0034554	3,3',5-tribromobisphenol A reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.
GO:0034555	3,3'-dibromobisphenol A reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.
GO:0034556	nitrobenzoate nitroreductase activity	molecular_function	Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.
GO:0034557	2-hydroxylaminobenzoate reductase activity	molecular_function	Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O.
GO:0034558	technetium (VII) reductase activity	molecular_function	Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-.
GO:0034559	bisphenol A hydroxylase B activity	molecular_function	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.
GO:0034560	bisphenol A hydroxylase A activity	molecular_function	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.
GO:0034561	1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity	molecular_function	Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.
GO:0034562	2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity	molecular_function	Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.
GO:0034563	2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.
GO:0034564	4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity	molecular_function	Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.
GO:0034565	1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity	molecular_function	Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.
GO:0034567	chromate reductase activity	molecular_function	Catalysis of the reaction: chromate = chromium (III).
GO:0034568	isoproturon dimethylaminedehydrogenase activity	molecular_function	Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.
GO:0034569	monodemethylisoproturon dehydrogenase activity	molecular_function	Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.
GO:0034570	hydroxymonomethylisoproturon dimethylaminedehydrogenase activity	molecular_function	Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.
GO:0034571	4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity	molecular_function	Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.
GO:0034572	monodemethylisoproturon dimethylaminedehydrogenase activity	molecular_function	Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.
GO:0034573	didemethylisoproturon amidohydrolase activity	molecular_function	Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline.
GO:0034574	didemethylisoproturon dehydrogenase activity	molecular_function	Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.
GO:0034575	4-isopropylaniline dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.
GO:0034576	N-isopropylacetanilide amidohydrolase activity	molecular_function	Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate.
GO:0034577	N-isopropylacetaniline monooxygenase activity	molecular_function	Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone.
GO:0034578	limonene 8-hydratase activity	molecular_function	Catalysis of the reaction: limonene + H2O = alpha-terpineol.
GO:0034579	(1-methylpentyl)succinate synthase activity	molecular_function	Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate.
GO:0034580	4-methyloctanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-.
GO:0034581	4-methyloct-2-enoyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.
GO:0034582	3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.
GO:0034583	21U-RNA binding	molecular_function	Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
GO:0034584	piRNA binding	molecular_function	Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
GO:0034585	21U-RNA metabolic process	biological_process	The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
GO:0034586	21U-RNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
GO:0034587	piRNA processing	biological_process	A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
GO:0034589	hydroxyproline transport	biological_process	The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034590	L-hydroxyproline transmembrane transporter activity	molecular_function	Enables the transfer of L-hydroxyproline from one side of a membrane to the other.
GO:0034591	rhoptry lumen	cellular_component	The volume enclosed by the rhoptry membrane.
GO:0034592	synaptic vesicle lumen	cellular_component	The volume enclosed by the synaptic vesicle membrane.
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	molecular_function	Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	molecular_function	Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.
GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
GO:0034598	phosphothreonine lyase activity	molecular_function	Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.
GO:0034599	cellular response to oxidative stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0034601	oxoglutarate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H.
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH.
GO:0034603	pyruvate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.
GO:0034604	pyruvate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.
GO:0034605	cellular response to heat	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0034606	response to hermaphrodite contact	biological_process	The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.
GO:0034607	turning behavior involved in mating	biological_process	The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
GO:0034608	vulval location	biological_process	Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
GO:0034609	spicule insertion	biological_process	Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
GO:0034610	oligodeoxyribonucleotidase activity	molecular_function	Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.
GO:0034611	oligoribonucleotidase activity	molecular_function	Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.
GO:0034612	response to tumor necrosis factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
GO:0034614	cellular response to reactive oxygen species	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
GO:0034615	GCH1 complex	cellular_component	A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.
GO:0034616	response to laminar fluid shear stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.
GO:0034617	tetrahydrobiopterin binding	molecular_function	Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.
GO:0034618	arginine binding	molecular_function	Binding to 2-amino-5-(carbamimidamido)pentanoic acid.
GO:0034620	cellular response to unfolded protein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
GO:0034625	fatty acid elongation, monounsaturated fatty acid	biological_process	Elongation of a fatty acid chain into which one C-C double bond has been introduced.
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	biological_process	Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced.
GO:0034627	'de novo' NAD biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0034628	'de novo' NAD biosynthetic process from aspartate	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0034630	RITS complex localization	biological_process	Any process in which a RITS complex is transported to, or maintained in, a specific location.
GO:0034631	microtubule anchoring at spindle pole body	biological_process	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
GO:0034632	retinol transmembrane transporter activity	molecular_function	Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.
GO:0034633	retinol transport	biological_process	The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.
GO:0034634	glutathione transmembrane transporter activity	molecular_function	Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.
GO:0034635	glutathione transport	biological_process	The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034638	phosphatidylcholine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
GO:0034639	L-amino acid efflux transmembrane transporter activity	molecular_function	Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.
GO:0034640	establishment of mitochondrion localization by microtubule attachment	biological_process	The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.
GO:0034641	cellular nitrogen compound metabolic process	biological_process	The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:0034642	mitochondrion migration along actin filament	biological_process	The directed movement of a mitochondrion along a microfilament, mediated by motor proteins.
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	biological_process	The directed movement of the mitochondrion to a specific location, by a process involving microtubules.
GO:0034644	cellular response to UV	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
GO:0034646	organelle-enclosing lipid monolayer	cellular_component	A lipid monolayer that surrounds and encloses an organelle.
GO:0034647	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0034650	cortisol metabolic process	biological_process	The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
GO:0034651	cortisol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
GO:0034653	retinoic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
GO:0034654	nucleobase-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0034655	nucleobase-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0034656	nucleobase-containing small molecule catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GO:0034657	GID complex	cellular_component	A protein complex with ubiquitin ligase activity that, in Saccharomyces cerevisiae, is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. It appears to play a broader role in cellular homeostasis and development in other species.
GO:0034658	isopropylmalate transmembrane transporter activity	molecular_function	Enables the transfer of isopropylmalate from one side of a membrane to the other.
GO:0034659	isopropylmalate transport	biological_process	The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034660	ncRNA metabolic process	biological_process	The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).
GO:0034661	ncRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).
GO:0034662	CFTR-NHERF-ezrin complex	cellular_component	A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.
GO:0034663	endoplasmic reticulum chaperone complex	cellular_component	A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.
GO:0034664	Ig heavy chain-bound endoplasmic reticulum chaperone complex	cellular_component	A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.
GO:0034665	integrin alpha1-beta1 complex	cellular_component	An integrin complex that comprises one alpha1 subunit and one beta1 subunit.
GO:0034666	integrin alpha2-beta1 complex	cellular_component	An integrin complex that comprises one alpha2 subunit and one beta1 subunit.
GO:0034667	integrin alpha3-beta1 complex	cellular_component	An integrin complex that comprises one alpha3 subunit and one beta1 subunit.
GO:0034668	integrin alpha4-beta1 complex	cellular_component	An integrin complex that comprises one alpha4 subunit and one beta1 subunit.
GO:0034669	integrin alpha4-beta7 complex	cellular_component	An integrin complex that comprises one alpha4 subunit and one beta7 subunit.
GO:0034670	chemotaxis to arachidonic acid	biological_process	The directed movement of a motile cell or organism in response to the presence of arachidonic acid.
GO:0034671	retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.
GO:0034672	anterior/posterior pattern specification involved in pronephros development	biological_process	The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
GO:0034673	inhibin-betaglycan-ActRII complex	cellular_component	A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.
GO:0034674	integrin alpha5-beta1 complex	cellular_component	An integrin complex that comprises one alpha5 subunit and one beta1 subunit.
GO:0034675	integrin alpha6-beta1 complex	cellular_component	An integrin complex that comprises one alpha6 subunit and one beta1 subunit.
GO:0034676	integrin alpha6-beta4 complex	cellular_component	An integrin complex that comprises one alpha6 subunit and one beta4 subunit.
GO:0034677	integrin alpha7-beta1 complex	cellular_component	An integrin complex that comprises one alpha7 subunit and one beta1 subunit.
GO:0034678	integrin alpha8-beta1 complex	cellular_component	An integrin complex that comprises one alpha8 subunit and one beta1 subunit.
GO:0034679	integrin alpha9-beta1 complex	cellular_component	An integrin complex that comprises one alpha9 subunit and one beta1 subunit.
GO:0034680	integrin alpha10-beta1 complex	cellular_component	An integrin complex that comprises one alpha10 subunit and one beta1 subunit.
GO:0034681	integrin alpha11-beta1 complex	cellular_component	An integrin complex that comprises one alpha11 subunit and one beta1 subunit.
GO:0034682	integrin alphav-beta1 complex	cellular_component	An integrin complex that comprises one alphav subunit and one beta1 subunit.
GO:0034683	integrin alphav-beta3 complex	cellular_component	An integrin complex that comprises one alphav subunit and one beta3 subunit.
GO:0034684	integrin alphav-beta5 complex	cellular_component	An integrin complex that comprises one alphav subunit and one beta5 subunit.
GO:0034685	integrin alphav-beta6 complex	cellular_component	An integrin complex that comprises one alphav subunit and one beta6 subunit.
GO:0034686	integrin alphav-beta8 complex	cellular_component	An integrin complex that comprises one alphav subunit and one beta8 subunit.
GO:0034687	integrin alphaL-beta2 complex	cellular_component	An integrin complex that comprises one alphaL subunit and one beta2 subunit.
GO:0034688	integrin alphaM-beta2 complex	cellular_component	An integrin complex that comprises one alphaM subunit and one beta2 subunit.
GO:0034689	integrin alphaX-beta2 complex	cellular_component	An integrin complex that comprises one alphaX subunit and one beta2 subunit.
GO:0034690	integrin alphaD-beta2 complex	cellular_component	An integrin complex that comprises one alphaD subunit and one beta2 subunit.
GO:0034691	integrin alphaE-beta7 complex	cellular_component	An integrin complex that comprises one alphaE subunit and one beta7 subunit.
GO:0034692	E.F.G complex	cellular_component	A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.
GO:0034693	U11/U12 snRNP	cellular_component	A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.
GO:0034694	response to prostaglandin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.
GO:0034695	response to prostaglandin E	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
GO:0034696	response to prostaglandin F	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.
GO:0034697	response to prostaglandin I	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.
GO:0034698	response to gonadotropin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
GO:0034699	response to luteinizing hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
GO:0034700	allulose 6-phosphate 3-epimerase activity	molecular_function	Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate.
GO:0034701	tripeptidase activity	molecular_function	Catalysis of the hydrolysis of a tripeptide.
GO:0034702	monoatomic ion channel complex	cellular_component	A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient.
GO:0034703	cation channel complex	cellular_component	An ion channel complex through which cations pass.
GO:0034704	calcium channel complex	cellular_component	An ion channel complex through which calcium ions pass.
GO:0034705	potassium channel complex	cellular_component	An ion channel complex through which potassium ions pass.
GO:0034706	sodium channel complex	cellular_component	An ion channel complex through which sodium ions pass.
GO:0034707	chloride channel complex	cellular_component	An ion channel complex through which chloride ions pass.
GO:0034708	methyltransferase complex	cellular_component	A protein complex that possesses methyltransferase activity.
GO:0034709	methylosome	cellular_component	A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.
GO:0034710	inhibin complex binding	molecular_function	Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.
GO:0034711	inhibin binding	molecular_function	Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
GO:0034713	type I transforming growth factor beta receptor binding	molecular_function	Binding to a type I transforming growth factor beta receptor.
GO:0034714	type III transforming growth factor beta receptor binding	molecular_function	Binding to a type III transforming growth factor beta receptor.
GO:0034715	pICln-Sm protein complex	cellular_component	A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.
GO:0034716	Gemin3-Gemin4-Gemin5 complex	cellular_component	A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.
GO:0034717	Gemin6-Gemin7-unrip complex	cellular_component	A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.
GO:0034718	SMN-Gemin2 complex	cellular_component	A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.
GO:0034719	SMN-Sm protein complex	cellular_component	A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
GO:0034720	histone H3-K4 demethylation	biological_process	The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	biological_process	The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.
GO:0034722	gamma-glutamyl-peptidase activity	molecular_function	Catalysis of the cleavage of a gamma-linked glutamate bond.
GO:0034727	piecemeal microautophagy of the nucleus	biological_process	Degradation of a cell nucleus by lysosomal microautophagy.
GO:0034728	nucleosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.
GO:0034729	histone H3-K79 methylation	biological_process	The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.
GO:0034730	SmD-containing SMN-Sm protein complex	cellular_component	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.
GO:0034731	Lsm-containing SMN-Sm protein complex	cellular_component	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.
GO:0034732	transcription factor TFIIIB-alpha complex	cellular_component	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.
GO:0034733	transcription factor TFIIIB-beta complex	cellular_component	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.
GO:0034734	transcription factor TFIIIC1 complex	cellular_component	A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.
GO:0034735	transcription factor TFIIIC2 complex	cellular_component	A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.
GO:0034736	cholesterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
GO:0034737	ergosterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester.
GO:0034738	lanosterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.
GO:0034739	histone H4K16 deacetylase activity	molecular_function	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.
GO:0034740	TFIIIC-TOP1-SUB1 complex	cellular_component	A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.
GO:0034741	APC-tubulin-IQGAP1 complex	cellular_component	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.
GO:0034743	APC-IQGAP complex	cellular_component	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
GO:0034744	APC-IQGAP1-Cdc42 complex	cellular_component	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
GO:0034745	APC-IQGAP1-Rac1 complex	cellular_component	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
GO:0034746	APC-IQGAP1-CLIP-170 complex	cellular_component	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.
GO:0034748	Par3-APC-KIF3A complex	cellular_component	A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.
GO:0034749	Scrib-APC complex	cellular_component	A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.
GO:0034750	Scrib-APC-beta-catenin complex	cellular_component	A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.
GO:0034751	aryl hydrocarbon receptor complex	cellular_component	A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.
GO:0034752	cytosolic aryl hydrocarbon receptor complex	cellular_component	An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.
GO:0034753	nuclear aryl hydrocarbon receptor complex	cellular_component	An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).
GO:0034755	iron ion transmembrane transport	biological_process	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0034756	regulation of iron ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034757	negative regulation of iron ion transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034758	positive regulation of iron ion transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0034759	regulation of iron ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0034760	negative regulation of iron ion transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0034761	positive regulation of iron ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0034762	regulation of transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GO:0034763	negative regulation of transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GO:0034764	positive regulation of transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GO:0034765	regulation of monoatomic ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GO:0034766	negative regulation of monoatomic ion transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GO:0034767	positive regulation of monoatomic ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GO:0034768	(E)-beta-ocimene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.
GO:0034769	basement membrane disassembly	biological_process	The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.
GO:0034770	histone H4-K20 methylation	biological_process	The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.
GO:0034772	histone H4-K20 dimethylation	biological_process	The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.
GO:0034773	histone H4-K20 trimethylation	biological_process	The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.
GO:0034774	secretory granule lumen	cellular_component	The volume enclosed by the membrane of a secretory granule.
GO:0034775	glutathione transmembrane transport	biological_process	A process in which glutathione is transported across a membrane.
GO:0034776	response to histamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
GO:0034777	recycling endosome lumen	cellular_component	The volume enclosed by the membranes of a recycling endosome.
GO:0034778	2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.
GO:0034779	4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.
GO:0034780	glyphosate dehydrogenase activity	molecular_function	Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.
GO:0034781	N-cyclohexylformamide amidohydrolase activity	molecular_function	Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.
GO:0034782	dimethylmalonate decarboxylase activity	molecular_function	Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.
GO:0034783	pivalate-CoA ligase activity	molecular_function	Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP.
GO:0034784	pivalyl-CoA mutase activity	molecular_function	Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
GO:0034785	salicylate 5-hydroxylase activity	molecular_function	Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.
GO:0034786	9-fluorenone-3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.
GO:0034787	1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.
GO:0034788	2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.
GO:0034789	2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.
GO:0034790	3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity	molecular_function	Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.
GO:0034791	isobutylamine N-hydroxylase activity	molecular_function	Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O.
GO:0034792	hypophosphite dioxygenase activity	molecular_function	Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2.
GO:0034793	cyclopropanecarboxylate-CoA ligase activity	molecular_function	Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-.
GO:0034794	cyclopropanecarboxyl-CoA decyclase activity	molecular_function	Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.
GO:0034795	cyclohexane monooxygenase activity	molecular_function	Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.
GO:0034796	adipate-CoA ligase activity	molecular_function	Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-.
GO:0034797	fosfomycin 2-glutathione ligase activity	molecular_function	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.
GO:0034798	fosfomycin 2-L-cysteine ligase activity	molecular_function	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.
GO:0034799	dihydride TNP tautomerase activity	molecular_function	Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).
GO:0034800	trinitrophenol dihydride denitratase activity	molecular_function	Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.
GO:0034801	2,4-dinitrocyclohexanone hydrolase activity	molecular_function	Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate.
GO:0034802	branched-chain dodecylbenzene sulfonate monooxygenase activity	molecular_function	Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.
GO:0034803	3-hydroxy-2-naphthoate 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.
GO:0034804	benzo(a)pyrene 11,12-epoxidase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide.
GO:0034805	benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.
GO:0034806	benzo(a)pyrene 11,12-dioxygenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.
GO:0034807	4,5-dihydroxybenzo(a)pyrene methyltransferase activity	molecular_function	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene.
GO:0034808	benzo(a)pyrene 4,5-dioxygenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.
GO:0034809	benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2.
GO:0034810	4,5-dihydroxybenzo(a)pyrene dioxygenase activity	molecular_function	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.
GO:0034811	benzo(a)pyrene 9,10-dioxygenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol.
GO:0034812	9,10-dihydroxybenzo(a)pyrene dioxygenase activity	molecular_function	Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.
GO:0034813	benzo(a)pyrene 7,8-dioxygenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol.
GO:0034814	7,8-dihydroxy benzo(a)pyrene dioxygenase activity	molecular_function	Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.
GO:0034815	cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity	molecular_function	Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.
GO:0034816	anthracene 9,10-dioxygenase activity	molecular_function	Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol.
GO:0034817	cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-.
GO:0034818	ADD 9alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.
GO:0034819	3-HSA hydroxylase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.
GO:0034820	4,9-DSHA hydrolase activity	molecular_function	Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.
GO:0034821	citronellol dehydrogenase activity	molecular_function	Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+.
GO:0034822	citronellal dehydrogenase activity	molecular_function	Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.
GO:0034823	citronellyl-CoA ligase activity	molecular_function	Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi.
GO:0034824	citronellyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.
GO:0034825	tetralin ring-hydroxylating dioxygenase activity	molecular_function	Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.
GO:0034826	1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.
GO:0034827	1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.
GO:0034828	4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.
GO:0034829	2-hydroxydec-2,4-diene-1,10-dioate hydratase activity	molecular_function	Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.
GO:0034830	(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity	molecular_function	Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate.
GO:0034831	(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.
GO:0034832	geranial dehydrogenase activity	molecular_function	Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+.
GO:0034833	geranylate CoA-transferase activity	molecular_function	Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-.
GO:0034834	2-mercaptobenzothiazole dioxygenase activity	molecular_function	Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.
GO:0034835	2-mercaptobenzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole.
GO:0034836	6-hydroxy-2-mercaptobenzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.
GO:0034837	2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.
GO:0034838	menthone dehydrogenase activity	molecular_function	Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+.
GO:0034839	menth-2-enone hydratase activity	molecular_function	Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone.
GO:0034840	3-hydroxymenthone dehydrogenase activity	molecular_function	Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+.
GO:0034841	mentha-1,3-dione-CoA ligase activity	molecular_function	Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA.
GO:0034842	thiophene-2-carboxylate-CoA ligase activity	molecular_function	Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.
GO:0034843	2-oxoglutaryl-CoA thioesterase activity	molecular_function	Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH.
GO:0034844	naphthyl-2-methyl-succinate CoA-transferase activity	molecular_function	Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.
GO:0034845	naphthyl-2-methyl-succinyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.
GO:0034846	naphthyl-2-methylene-succinyl-CoA lyase activity	molecular_function	Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.
GO:0034847	naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.
GO:0034848	naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity	molecular_function	Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.
GO:0034849	2-naphthoate CoA-transferase activity	molecular_function	Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH.
GO:0034850	isooctane monooxygenase activity	molecular_function	Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol.
GO:0034851	2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.
GO:0034852	4,4-dimethyl-3-oxopentanal dehydrogenase activity	molecular_function	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.
GO:0034853	2,4,4-trimethyl-3-oxopentanoate decarboxylase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2.
GO:0034854	4,4-dimethyl-3-oxopentanoate decarboxylase activity	molecular_function	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2.
GO:0034855	4-AD 9alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.
GO:0034856	2-hydroxyhexa-2,4-dienoate hydratase activity	molecular_function	Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.
GO:0034857	2-(methylthio)benzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole.
GO:0034858	2-hydroxybenzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole.
GO:0034859	benzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole.
GO:0034860	2-mercaptobenzothiazole desulfurase activity	molecular_function	Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.
GO:0034861	benzothiazole-2-sulfonate hydrolase activity	molecular_function	Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-.
GO:0034862	2,6-dihydroxybenzothiazole monooxygenase activity	molecular_function	Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.
GO:0034863	2,4,4-trimethyl-1-pentanol dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-.
GO:0034864	2,4,4-trimethylpentanal dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-.
GO:0034865	2,4,4-trimethylpentanoate-CoA ligase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.
GO:0034866	2,4,4-trimethylpentanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.
GO:0034867	2,4,4-trimethylpent-2-enoyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.
GO:0034868	2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.
GO:0034869	2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity	molecular_function	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.
GO:0034870	pinacolone 5-monooxygenase activity	molecular_function	Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one.
GO:0034871	1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity	molecular_function	Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.
GO:0034872	trans-geranyl-CoA isomerase activity	molecular_function	Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.
GO:0034873	thioacetamide S-oxygenase activity	molecular_function	Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O.
GO:0034874	thioacetamide S-oxide S-oxygenase activity	molecular_function	Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.
GO:0034875	caffeine oxidase activity	molecular_function	Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.
GO:0034876	isonicotinic acid hydrazide hydrolase activity	molecular_function	Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine.
GO:0034877	isonicotinate dehydrogenase activity	molecular_function	Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.
GO:0034878	2-hydroxyisonicotinate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.
GO:0034879	2,3,6-trihydroxyisonicotinate decarboxylase activity	molecular_function	Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.
GO:0034880	citrazinate dehydrogenase activity	molecular_function	Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.
GO:0034881	citrazinate hydrolase activity	molecular_function	Catalysis of the reaction: citrazinate + H2O = cis-aconitamide.
GO:0034882	cis-aconitamide amidase activity	molecular_function	Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3.
GO:0034885	gamma-N-formylaminovinylacetate hydrolase activity	molecular_function	Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH.
GO:0034886	gamma-aminovinylacetate deaminase activity	molecular_function	Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3.
GO:0034888	endosulfan monooxygenase I activity	molecular_function	Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O.
GO:0034889	endosulfan hemisulfate sulfatase activity	molecular_function	Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate.
GO:0034890	endosulfan diol hydrolyase (cyclizing) activity	molecular_function	Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O.
GO:0034891	endosulfan diol dehydrogenase activity	molecular_function	Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.
GO:0034892	endosulfan lactone lactonase activity	molecular_function	Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.
GO:0034893	N-nitrodimethylamine hydroxylase activity	molecular_function	Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.
GO:0034894	4-hydroxypyridine-3-hydroxylase activity	molecular_function	Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+.
GO:0034895	pyridine-3,4-diol dioxygenase activity	molecular_function	Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.
GO:0034896	3-formiminopyruvate hydrolase activity	molecular_function	Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3.
GO:0034897	4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity	molecular_function	Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.
GO:0034898	hexadecyltrimethylammonium chloride monooxygenase activity	molecular_function	Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.
GO:0034899	trimethylamine monooxygenase activity	molecular_function	Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.
GO:0034900	3-(N-formyl)-formiminopyruvate hydrolase activity	molecular_function	Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.
GO:0034901	endosulfan hydroxyether dehydrogenase activity	molecular_function	Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-.
GO:0034902	endosulfan sulfate hydrolase activity	molecular_function	Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite.
GO:0034903	endosulfan ether monooxygenase activity	molecular_function	Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.
GO:0034904	5-chloro-2-oxopent-4-enoate hydratase activity	molecular_function	Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.
GO:0034905	5-chloro-4-hydroxy-2-oxopentanate aldolase activity	molecular_function	Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.
GO:0034906	N-isopropylaniline 1,2-dixoxygenase activity	molecular_function	Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.
GO:0034907	acetanilide 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide.
GO:0034908	2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.
GO:0034909	6-hydroxypseudooxynicotine dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.
GO:0034910	6-hydroxy-3-succinoylpyridine hydrolase activity	molecular_function	Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.
GO:0034911	phthalate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+.
GO:0034912	phthalate 3,4-cis-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.
GO:0034914	trinitrophenol hydride denitratase activity	molecular_function	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.
GO:0034915	2-methylhexanoyl-CoA C-acetyltransferase activity	molecular_function	Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.
GO:0034916	2-methylhexanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.
GO:0034917	2-methylhex-2-enoyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA.
GO:0034918	3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.
GO:0034919	butyryl-CoA 2-C-propionyltransferase activity	molecular_function	Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA.
GO:0034920	pyrene dioxygenase activity	molecular_function	Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.
GO:0034921	cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-.
GO:0034922	4,5-dihydroxypyrene dioxygenase activity	molecular_function	Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+.
GO:0034923	phenanthrene-4,5-dicarboxylate decarboxylase activity	molecular_function	Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2.
GO:0034924	cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.
GO:0034925	pyrene 4,5-monooxygenase activity	molecular_function	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O.
GO:0034926	pyrene-4,5-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene.
GO:0034927	pyrene 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O.
GO:0034928	1-hydroxypyrene 6,7-monooxygenase activity	molecular_function	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.
GO:0034929	1-hydroxypyrene 7,8-monooxygenase activity	molecular_function	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O.
GO:0034930	1-hydroxypyrene sulfotransferase activity	molecular_function	Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX.
GO:0034931	1-hydroxypyrene methyltransferase activity	molecular_function	Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.
GO:0034932	1-methoxypyrene 6,7-monooxygenase activity	molecular_function	Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O.
GO:0034933	1-hydroxy-6-methoxypyrene methyltransferase activity	molecular_function	Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX.
GO:0034934	phenanthrene-4-carboxylate dioxygenase activity	molecular_function	Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.
GO:0034935	tetrachlorobenzene dioxygenase activity	molecular_function	Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.
GO:0034936	4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.
GO:0034937	perchlorate reductase activity	molecular_function	Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.
GO:0034938	pyrrole-2-carboxylate monooxygenase activity	molecular_function	Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.
GO:0034939	5-hydroxypyrrole-2-carboxylate tautomerase activity	molecular_function	Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.
GO:0034940	5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity	molecular_function	Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3.
GO:0034941	pyrrole-2-carboxylate decarboxylase activity	molecular_function	Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2.
GO:0034942	cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	molecular_function	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.
GO:0034943	trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	molecular_function	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.
GO:0034944	3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.
GO:0034945	2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	molecular_function	Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.
GO:0034946	3-isopropylbut-3-enoyl-CoA thioesterase activity	molecular_function	Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.
GO:0034947	terephthalate decarboxylase activity	molecular_function	Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.
GO:0034948	2,6-dihydroxypseudooxynicotine hydrolase activity	molecular_function	Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.
GO:0034949	1,1-dichloroethane reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl.
GO:0034950	phenylboronic acid monooxygenase activity	molecular_function	Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3.
GO:0034951	o-hydroxylaminobenzoate mutase activity	molecular_function	Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate.
GO:0034952	malonate semialdehyde decarboxylase activity	molecular_function	Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.
GO:0034953	perillyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA.
GO:0034954	diphenyl ether 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.
GO:0034955	2,3-dihydroxydiphenyl ether dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol.
GO:0034956	diphenyl ether 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.
GO:0034957	3-nitrophenol nitroreductase activity	molecular_function	Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O.
GO:0034958	aminohydroquinone monooxygenase activity	molecular_function	Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3.
GO:0034959	endothelin maturation	biological_process	The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.
GO:0034963	box C/D RNA processing	biological_process	Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.
GO:0034964	box H/ACA RNA processing	biological_process	Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.
GO:0034965	intronic box C/D RNA processing	biological_process	Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.
GO:0034966	intronic box H/ACA snoRNA processing	biological_process	Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.
GO:0034967	Set3 complex	cellular_component	A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.
GO:0034968	histone lysine methylation	biological_process	The modification of a histone by addition of one or more methyl groups to a lysine residue.
GO:0034969	histone arginine methylation	biological_process	The modification of a histone by addition of a methyl group to an arginine residue.
GO:0034970	histone H3-R2 methylation	biological_process	The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.
GO:0034971	histone H3-R17 methylation	biological_process	The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
GO:0034972	histone H3-R26 methylation	biological_process	The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.
GO:0034973	Sid2-Mob1 complex	cellular_component	A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.
GO:0034974	Swi5-Swi2 complex	cellular_component	A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.
GO:0034975	protein folding in endoplasmic reticulum	biological_process	A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
GO:0034976	response to endoplasmic reticulum stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GO:0034977	ABIN2-NFKB1-MAP3K8 complex	cellular_component	A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.
GO:0034978	PDX1-PBX1b-MRG1 complex	cellular_component	A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.
GO:0034979	NAD-dependent protein deacetylase activity	molecular_function	Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.
GO:0034980	FHL2-CREB complex	cellular_component	A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation.
GO:0034981	FHL3-CREB complex	cellular_component	A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation.
GO:0034982	mitochondrial protein processing	biological_process	The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.
GO:0034983	peptidyl-lysine deacetylation	biological_process	The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.
GO:0034985	Ecsit-NDUFAF1 complex	cellular_component	Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.
GO:0034986	iron chaperone activity	molecular_function	Directly binding to and delivering iron ions to a target protein.
GO:0034987	immunoglobulin receptor binding	molecular_function	Binding to one or more specific sites on an immunoglobulin receptor molecule.
GO:0034988	Fc-gamma receptor I complex binding	molecular_function	Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
GO:0034992	microtubule organizing center attachment site	cellular_component	A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.
GO:0034993	meiotic nuclear membrane microtubule tethering complex	cellular_component	A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.
GO:0034994	microtubule organizing center attachment site organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.
GO:0034995	SC5b-7 complex	cellular_component	A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.
GO:0034996	RasGAP-Fyn-Lyn-Yes complex	cellular_component	A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.
GO:0034997	alphav-beta5 integrin-vitronectin complex	cellular_component	A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.
GO:0034998	oligosaccharyltransferase I complex	cellular_component	An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.
GO:0034999	oligosaccharyltransferase II complex	cellular_component	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.
GO:0035000	oligosaccharyltransferase III complex	cellular_component	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.
GO:0035001	dorsal trunk growth, open tracheal system	biological_process	Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.
GO:0035002	liquid clearance, open tracheal system	biological_process	The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
GO:0035003	subapical complex	cellular_component	The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H+.
GO:0035006	melanization defense response	biological_process	The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
GO:0035007	regulation of melanization defense response	biological_process	Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.
GO:0035008	positive regulation of melanization defense response	biological_process	Any process that increases the rate or extent of the melanization defense response during injury or invasion.
GO:0035009	negative regulation of melanization defense response	biological_process	Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.
GO:0035010	encapsulation of foreign target	biological_process	Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.
GO:0035011	melanotic encapsulation of foreign target	biological_process	Formation of a multilayered, melanized sheath of cells around a foreign invader.
GO:0035013	myosuppressin receptor activity	molecular_function	Combining with the peptide myosuppressin to initiate a change in cell activity.
GO:0035014	phosphatidylinositol 3-kinase regulator activity	molecular_function	Modulates the activity of a phosphatidylinositol 3-kinase (PI3K). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.
GO:0035015	elongation of arista core	biological_process	The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.
GO:0035016	elongation of arista lateral	biological_process	The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.
GO:0035017	cuticle pattern formation	biological_process	The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.
GO:0035018	adult chitin-based cuticle pattern formation	biological_process	The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.
GO:0035019	somatic stem cell population maintenance	biological_process	Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
GO:0035020	regulation of Rac protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
GO:0035021	negative regulation of Rac protein signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.
GO:0035022	positive regulation of Rac protein signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
GO:0035023	regulation of Rho protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
GO:0035024	negative regulation of Rho protein signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
GO:0035025	positive regulation of Rho protein signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
GO:0035026	leading edge cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.
GO:0035027	leading edge cell fate commitment	biological_process	The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.
GO:0035028	leading edge cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0035029	dorsal closure, leading edge cell fate commitment	biological_process	The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.
GO:0035032	phosphatidylinositol 3-kinase complex, class III	cellular_component	A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
GO:0035033	histone deacetylase regulator activity	molecular_function	Binds to and modulates the activity of histone deacetylase.
GO:0035034	histone acetyltransferase regulator activity	molecular_function	Binds to and modulates the activity of histone acetyltransferase.
GO:0035035	histone acetyltransferase binding	molecular_function	Binding to an histone acetyltransferase.
GO:0035036	sperm-egg recognition	biological_process	The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.
GO:0035037	sperm entry	biological_process	An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.
GO:0035038	female pronucleus assembly	biological_process	Assembly of the haploid nucleus of the unfertilized egg.
GO:0035039	male pronucleus assembly	biological_process	The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.
GO:0035040	sperm nuclear envelope removal	biological_process	Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.
GO:0035041	sperm DNA decondensation	biological_process	Unwinding of the condensed nuclear chromatin of an inactive male pronucleus after fertilization.
GO:0035043	male pronuclear envelope synthesis	biological_process	Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.
GO:0035044	sperm aster formation	biological_process	Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.
GO:0035045	sperm plasma membrane disassembly	biological_process	The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.
GO:0035046	pronuclear migration	biological_process	The directed movement of the male and female pronuclei towards each other prior to their fusion.
GO:0035047	centrosomal and pronuclear rotation	biological_process	The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.
GO:0035049	juvenile hormone acid methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to juvenile hormone acid.
GO:0035050	embryonic heart tube development	biological_process	The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
GO:0035051	cardiocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
GO:0035052	dorsal vessel aortic cell fate commitment	biological_process	The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.
GO:0035053	dorsal vessel heart proper cell fate commitment	biological_process	The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.
GO:0035054	embryonic heart tube anterior/posterior pattern specification	biological_process	The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
GO:0035059	RCAF complex	cellular_component	A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.
GO:0035060	brahma complex	cellular_component	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.
GO:0035061	interchromatin granule	cellular_component	A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
GO:0035062	omega speckle	cellular_component	A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).
GO:0035063	nuclear speck organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.
GO:0035064	methylated histone binding	molecular_function	Binding to a histone in which a residue has been modified by methylation.
GO:0035065	regulation of histone acetylation	biological_process	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.
GO:0035066	positive regulation of histone acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
GO:0035067	negative regulation of histone acetylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.
GO:0035069	larval midgut histolysis	biological_process	The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
GO:0035070	salivary gland histolysis	biological_process	The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
GO:0035071	salivary gland cell autophagic cell death	biological_process	The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death	biological_process	Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.
GO:0035073	pupariation	biological_process	The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.
GO:0035074	pupation	biological_process	The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.
GO:0035075	response to ecdysone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
GO:0035076	ecdysone receptor-mediated signaling pathway	biological_process	The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex.
GO:0035077	ecdysone-mediated polytene chromosome puffing	biological_process	The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.
GO:0035078	induction of programmed cell death by ecdysone	biological_process	Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.
GO:0035079	polytene chromosome puffing	biological_process	The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.
GO:0035080	heat shock-mediated polytene chromosome puffing	biological_process	The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.
GO:0035081	induction of programmed cell death by hormones	biological_process	Any process induced by hormones that directly activates any of the steps required for programmed cell death.
GO:0035082	axoneme assembly	biological_process	The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GO:0035088	establishment or maintenance of apical/basal cell polarity	biological_process	Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
GO:0035089	establishment of apical/basal cell polarity	biological_process	The specification and formation of the polarity of a cell along its apical/basal axis.
GO:0035090	maintenance of apical/basal cell polarity	biological_process	Retaining the established polarization of a cell along its apical/basal axis.
GO:0035091	phosphatidylinositol binding	molecular_function	Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
GO:0035092	sperm DNA condensation	biological_process	The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
GO:0035094	response to nicotine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
GO:0035095	behavioral response to nicotine	biological_process	Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
GO:0035096	larval midgut cell programmed cell death	biological_process	The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.
GO:0035097	histone methyltransferase complex	cellular_component	A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.
GO:0035098	ESC/E(Z) complex	cellular_component	A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
GO:0035099	hemocyte migration	biological_process	The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.
GO:0035100	ecdysone binding	molecular_function	Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.
GO:0035101	FACT complex	cellular_component	A histone chaperone complex that facilitates nucleosome disassembly and reassembly upon DNA or RNA polymerase passage.
GO:0035102	PRC1 complex	cellular_component	A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
GO:0035106	operant conditioning	biological_process	Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
GO:0035107	appendage morphogenesis	biological_process	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
GO:0035108	limb morphogenesis	biological_process	The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
GO:0035112	genitalia morphogenesis	biological_process	The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.
GO:0035113	embryonic appendage morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
GO:0035114	imaginal disc-derived appendage morphogenesis	biological_process	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.
GO:0035115	embryonic forelimb morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
GO:0035116	embryonic hindlimb morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
GO:0035118	embryonic pectoral fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
GO:0035119	embryonic pelvic fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
GO:0035120	post-embryonic appendage morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
GO:0035122	embryonic medial fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
GO:0035123	embryonic dorsal fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
GO:0035124	embryonic caudal fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
GO:0035125	embryonic anal fin morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
GO:0035126	post-embryonic genitalia morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.
GO:0035127	post-embryonic limb morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
GO:0035128	post-embryonic forelimb morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.
GO:0035129	post-embryonic hindlimb morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.
GO:0035130	post-embryonic pectoral fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
GO:0035131	post-embryonic pelvic fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
GO:0035132	post-embryonic medial fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
GO:0035133	post-embryonic caudal fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
GO:0035134	post-embryonic dorsal fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
GO:0035135	post-embryonic anal fin morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
GO:0035136	forelimb morphogenesis	biological_process	The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
GO:0035137	hindlimb morphogenesis	biological_process	The process in which the anatomical structures of the hindlimb are generated and organized.
GO:0035138	pectoral fin morphogenesis	biological_process	The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
GO:0035139	pelvic fin morphogenesis	biological_process	The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
GO:0035141	medial fin morphogenesis	biological_process	The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
GO:0035142	dorsal fin morphogenesis	biological_process	The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
GO:0035143	caudal fin morphogenesis	biological_process	The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.
GO:0035144	anal fin morphogenesis	biological_process	The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
GO:0035145	exon-exon junction complex	cellular_component	A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
GO:0035146	tube fusion	biological_process	The joining of specific branches of a tubular system to form a continuous network.
GO:0035147	branch fusion, open tracheal system	biological_process	Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
GO:0035148	tube formation	biological_process	Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.
GO:0035149	lumen formation, open tracheal system	biological_process	Creation of the central hole of a tube in an open tracheal system through which gases flow.
GO:0035150	regulation of tube size	biological_process	Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.
GO:0035151	regulation of tube size, open tracheal system	biological_process	Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
GO:0035152	regulation of tube architecture, open tracheal system	biological_process	Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.
GO:0035153	epithelial cell type specification, open tracheal system	biological_process	Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.
GO:0035154	terminal cell fate specification, open tracheal system	biological_process	The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.
GO:0035155	negative regulation of terminal cell fate specification, open tracheal system	biological_process	Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
GO:0035156	fusion cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.
GO:0035157	negative regulation of fusion cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
GO:0035158	regulation of tube diameter, open tracheal system	biological_process	Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.
GO:0035159	regulation of tube length, open tracheal system	biological_process	Ensuring that a tube in an open tracheal system is of the correct length.
GO:0035160	maintenance of epithelial integrity, open tracheal system	biological_process	Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.
GO:0035161	imaginal disc lineage restriction	biological_process	Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.
GO:0035162	embryonic hemopoiesis	biological_process	The stages of blood cell formation that take place within the embryo.
GO:0035163	embryonic hemocyte differentiation	biological_process	The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
GO:0035164	embryonic plasmatocyte differentiation	biological_process	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.
GO:0035165	embryonic crystal cell differentiation	biological_process	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
GO:0035166	post-embryonic hemopoiesis	biological_process	The stages of blood cell formation that take place after completion of embryonic development.
GO:0035167	larval lymph gland hemopoiesis	biological_process	The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
GO:0035168	larval lymph gland hemocyte differentiation	biological_process	The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
GO:0035169	lymph gland plasmatocyte differentiation	biological_process	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.
GO:0035170	lymph gland crystal cell differentiation	biological_process	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
GO:0035171	lamellocyte differentiation	biological_process	The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
GO:0035172	hemocyte proliferation	biological_process	The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
GO:0035173	histone kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone.
GO:0035175	histone H3S10 kinase activity	molecular_function	Catalysis of the reaction: histone H3-serine (position 10) + ATP = histone H3-phosphoserine (position 10) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 10 of histone H3.
GO:0035176	social behavior	biological_process	Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
GO:0035177	larval foraging behavior	biological_process	The movement of a larva through a feeding substrate whilst feeding on food.
GO:0035178	turning behavior	biological_process	Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.
GO:0035179	larval turning behavior	biological_process	Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.
GO:0035180	larval wandering behavior	biological_process	The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.
GO:0035181	larval burrowing behavior	biological_process	Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.
GO:0035182	female germline ring canal outer rim	cellular_component	An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.
GO:0035183	female germline ring canal inner rim	cellular_component	A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.
GO:0035185	preblastoderm mitotic cell cycle	biological_process	The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.
GO:0035186	syncytial blastoderm mitotic cell cycle	biological_process	Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.
GO:0035187	hatching behavior	biological_process	The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.
GO:0035188	hatching	biological_process	The emergence of an immature organism from a protective structure.
GO:0035189	Rb-E2F complex	cellular_component	A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.
GO:0035190	syncytial nuclear migration	biological_process	The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.
GO:0035191	nuclear axial expansion	biological_process	The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.
GO:0035192	nuclear cortical migration	biological_process	The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.
GO:0035193	larval central nervous system remodeling	biological_process	Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.
GO:0035194	regulatory ncRNA-mediated post-transcriptional gene silencing	biological_process	A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.
GO:0035195	miRNA-mediated post-transcriptional gene silencing	biological_process	A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants.
GO:0035196	miRNA processing	biological_process	A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.
GO:0035197	siRNA binding	molecular_function	Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.
GO:0035198	miRNA binding	molecular_function	Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
GO:0035199	salt aversion	biological_process	The specific avoidance actions or reactions of an organism in response to the perception of salt.
GO:0035200	leg disc anterior/posterior pattern formation	biological_process	The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.
GO:0035201	leg disc anterior/posterior lineage restriction	biological_process	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.
GO:0035202	tracheal pit formation in open tracheal system	biological_process	Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.
GO:0035203	regulation of lamellocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
GO:0035204	negative regulation of lamellocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
GO:0035205	positive regulation of lamellocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
GO:0035206	regulation of hemocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
GO:0035207	negative regulation of hemocyte proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
GO:0035208	positive regulation of hemocyte proliferation	biological_process	Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
GO:0035209	pupal development	biological_process	The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.
GO:0035210	prepupal development	biological_process	The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.
GO:0035211	spermathecum morphogenesis	biological_process	The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.
GO:0035212	cell competition in a multicellular organism	biological_process	Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.
GO:0035213	clypeo-labral disc development	biological_process	The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.
GO:0035214	eye-antennal disc development	biological_process	Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.
GO:0035215	genital disc development	biological_process	Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.
GO:0035216	haltere disc development	biological_process	Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.
GO:0035217	labial disc development	biological_process	Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.
GO:0035218	leg disc development	biological_process	Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.
GO:0035219	prothoracic disc development	biological_process	Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.
GO:0035220	wing disc development	biological_process	Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
GO:0035221	genital disc pattern formation	biological_process	The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.
GO:0035222	wing disc pattern formation	biological_process	The process giving rise to the pattern of cell differentiation in the wing imaginal disc.
GO:0035223	leg disc pattern formation	biological_process	The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.
GO:0035224	genital disc anterior/posterior pattern formation	biological_process	The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).
GO:0035225	determination of genital disc primordium	biological_process	Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.
GO:0035226	glutamate-cysteine ligase catalytic subunit binding	molecular_function	Binding to the catalytic subunit of glutamate-cysteine ligase.
GO:0035227	regulation of glutamate-cysteine ligase activity	biological_process	Any process that modulates the activity of glutamate-cysteine ligase.
GO:0035228	negative regulation of glutamate-cysteine ligase activity	biological_process	Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase.
GO:0035229	positive regulation of glutamate-cysteine ligase activity	biological_process	Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.
GO:0035230	cytoneme	cellular_component	A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.
GO:0035231	cytoneme assembly	biological_process	Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.
GO:0035232	germ cell attraction	biological_process	The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.
GO:0035233	germ cell repulsion	biological_process	The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.
GO:0035234	ectopic germ cell programmed cell death	biological_process	Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.
GO:0035235	ionotropic glutamate receptor signaling pathway	biological_process	The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035236	proctolin receptor activity	molecular_function	Combining with the neuropeptide proctolin, to initiate a change in cell activity.
GO:0035237	corazonin receptor activity	molecular_function	Combining with the neuropeptide corazonin to initiate a change in cell activity.
GO:0035238	vitamin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.
GO:0035239	tube morphogenesis	biological_process	The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
GO:0035240	dopamine binding	molecular_function	Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.
GO:0035241	protein-arginine omega-N monomethyltransferase activity	molecular_function	Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.
GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	molecular_function	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.
GO:0035243	protein-arginine omega-N symmetric methyltransferase activity	molecular_function	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.
GO:0035244	protein-arginine C-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein. This modification has been detected in anaerobic bacteria.
GO:0035246	peptidyl-arginine N-methylation	biological_process	The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein.
GO:0035247	peptidyl-arginine omega-N-methylation	biological_process	The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.
GO:0035248	alpha-1,4-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.
GO:0035249	synaptic transmission, glutamatergic	biological_process	The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0035250	UDP-galactosyltransferase activity	molecular_function	Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule.
GO:0035251	UDP-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.
GO:0035252	UDP-xylosyltransferase activity	molecular_function	Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.
GO:0035253	ciliary rootlet	cellular_component	A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.
GO:0035254	glutamate receptor binding	molecular_function	Binding to a glutamate receptor.
GO:0035255	ionotropic glutamate receptor binding	molecular_function	Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.
GO:0035256	G protein-coupled glutamate receptor binding	molecular_function	Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor).
GO:0035259	nuclear glucocorticoid receptor binding	molecular_function	Binding to a nuclear glucocorticoid receptor.
GO:0035260	internal genitalia morphogenesis	biological_process	The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.
GO:0035261	external genitalia morphogenesis	biological_process	The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.
GO:0035262	gonad morphogenesis	biological_process	The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
GO:0035263	genital disc sexually dimorphic development	biological_process	The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.
GO:0035264	multicellular organism growth	biological_process	The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
GO:0035265	organ growth	biological_process	The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.
GO:0035266	meristem growth	biological_process	The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.
GO:0035267	NuA4 histone acetyltransferase complex	cellular_component	A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).
GO:0035268	protein mannosylation	biological_process	The addition of a mannose residue to a protein acceptor molecule.
GO:0035269	protein O-linked mannosylation	biological_process	The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.
GO:0035270	endocrine system development	biological_process	Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.
GO:0035271	ring gland development	biological_process	Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.
GO:0035272	exocrine system development	biological_process	Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.
GO:0035273	phthalate binding	molecular_function	Binding to a phthalate, any ester or salt of phthalic acid.
GO:0035274	diphenyl phthalate binding	molecular_function	Binding to diphenyl phthalate, C(20)H(14)O(4).
GO:0035275	dibutyl phthalate binding	molecular_function	Binding to dibutyl phthalate, C(16)H(22)O(4).
GO:0035276	ethanol binding	molecular_function	Binding to ethanol, CH(3)-CH(2)-OH.
GO:0035277	spiracle morphogenesis, open tracheal system	biological_process	The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.
GO:0035278	miRNA-mediated gene silencing by inhibition of translation	biological_process	An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.
GO:0035279	miRNA-mediated gene silencing by mRNA destabilization	biological_process	An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
GO:0035281	pre-miRNA export from nucleus	biological_process	Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.
GO:0035282	segmentation	biological_process	The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.
GO:0035283	central nervous system segmentation	biological_process	Division of the central nervous system into a series of semi-repetitive parts or segments.
GO:0035284	brain segmentation	biological_process	Division of the brain into a series of semi-repetitive parts or segments.
GO:0035285	appendage segmentation	biological_process	Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.
GO:0035287	head segmentation	biological_process	Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).
GO:0035288	anterior head segmentation	biological_process	Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.
GO:0035289	posterior head segmentation	biological_process	Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.
GO:0035290	trunk segmentation	biological_process	Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.
GO:0035291	specification of segmental identity, intercalary segment	biological_process	The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0035292	specification of segmental identity, trunk	biological_process	The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0035293	chitin-based larval cuticle pattern formation	biological_process	The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.
GO:0035294	determination of wing disc primordium	biological_process	Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.
GO:0035295	tube development	biological_process	The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.
GO:0035296	regulation of tube diameter	biological_process	Any process that modulates the diameter of a tube.
GO:0035297	regulation of Malpighian tubule diameter	biological_process	Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.
GO:0035298	regulation of Malpighian tubule size	biological_process	Ensuring that a Malpighian tubule is the correct length and diameter.
GO:0035299	inositol pentakisphosphate 2-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H+.
GO:0035301	Hedgehog signaling complex	cellular_component	A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).
GO:0035302	ecdysteroid 25-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.
GO:0035303	regulation of dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
GO:0035304	regulation of protein dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.
GO:0035305	negative regulation of dephosphorylation	biological_process	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.
GO:0035306	positive regulation of dephosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.
GO:0035307	positive regulation of protein dephosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
GO:0035308	negative regulation of protein dephosphorylation	biological_process	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.
GO:0035309	wing and notum subfield formation	biological_process	The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.
GO:0035310	notum cell fate specification	biological_process	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
GO:0035311	wing cell fate specification	biological_process	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.
GO:0035312	5'-3' DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.
GO:0035313	wound healing, spreading of epidermal cells	biological_process	The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.
GO:0035314	scab formation	biological_process	Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
GO:0035315	hair cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a hair cell.
GO:0035316	non-sensory hair organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.
GO:0035317	imaginal disc-derived wing hair organization	biological_process	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.
GO:0035318	imaginal disc-derived wing hair outgrowth	biological_process	Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.
GO:0035319	imaginal disc-derived wing hair elongation	biological_process	Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.
GO:0035320	imaginal disc-derived wing hair site selection	biological_process	Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.
GO:0035321	maintenance of imaginal disc-derived wing hair orientation	biological_process	Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.
GO:0035322	mesenchymal cell migration involved in limb bud formation	biological_process	The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.
GO:0035323	male germline ring canal	cellular_component	An intercellular bridge that connects the germline cells of a male cyst.
GO:0035324	female germline ring canal	cellular_component	An intercellular bridge that connects the germline cells of a female cyst.
GO:0035325	Toll-like receptor binding	molecular_function	Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0035329	hippo signaling	biological_process	The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
GO:0035330	regulation of hippo signaling	biological_process	Any process that modulates the frequency, rate or extent of hippo signaling.
GO:0035331	negative regulation of hippo signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
GO:0035332	positive regulation of hippo signaling	biological_process	Any process that activates or increases the frequency, rate or extent of hippo signaling.
GO:0035333	Notch receptor processing, ligand-dependent	biological_process	The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).
GO:0035334	Notch receptor processing, ligand-independent	biological_process	The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.
GO:0035335	peptidyl-tyrosine dephosphorylation	biological_process	The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
GO:0035336	long-chain fatty-acyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
GO:0035337	fatty-acyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
GO:0035339	SPOTS complex	cellular_component	A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.
GO:0035340	inosine transport	biological_process	The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035341	regulation of inosine transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035342	positive regulation of inosine transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035343	negative regulation of inosine transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035344	hypoxanthine transport	biological_process	The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035345	regulation of hypoxanthine transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035346	positive regulation of hypoxanthine transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035347	negative regulation of hypoxanthine transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035348	acetyl-CoA transmembrane transport	biological_process	The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
GO:0035349	coenzyme A transmembrane transport	biological_process	The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0035350	FAD transmembrane transport	biological_process	The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
GO:0035351	heme transmembrane transport	biological_process	The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0035352	NAD transmembrane transport	biological_process	The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0035353	nicotinamide mononucleotide transmembrane transport	biological_process	The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.
GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex	cellular_component	A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).
GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex	cellular_component	A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).
GO:0035356	intracellular triglyceride homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell.
GO:0035357	peroxisome proliferator activated receptor signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
GO:0035361	Cul8-RING ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.
GO:0035362	protein-DNA ISRE complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.
GO:0035363	histone locus body	cellular_component	A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.
GO:0035364	thymine transport	biological_process	The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035365	regulation of thymine transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035366	negative regulation of thymine transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035367	positive regulation of thymine transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0035368	selenocysteine insertion sequence binding	molecular_function	Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.
GO:0035369	pre-B cell receptor complex	cellular_component	An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0035370	UBC13-UEV1A complex	cellular_component	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).
GO:0035371	microtubule plus-end	cellular_component	The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
GO:0035372	protein localization to microtubule	biological_process	A process in which a protein is transported to, or maintained at, a microtubule.
GO:0035373	chondroitin sulfate proteoglycan binding	molecular_function	Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.
GO:0035374	chondroitin sulfate binding	molecular_function	Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
GO:0035375	zymogen binding	molecular_function	Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
GO:0035376	sterol import	biological_process	The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0035377	transepithelial water transport	biological_process	The directed movement of water (H2O) from one side of an epithelium to the other.
GO:0035378	carbon dioxide transmembrane transport	biological_process	The process in which carbon dioxide (CO2) is transported across a membrane.
GO:0035379	carbon dioxide transmembrane transporter activity	molecular_function	Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.
GO:0035380	very long-chain-3-hydroxyacyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
GO:0035381	ATP-gated ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.
GO:0035382	sterol transmembrane transport	biological_process	The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0035383	thioester metabolic process	biological_process	The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
GO:0035384	thioester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
GO:0035385	Roundabout signaling pathway	biological_process	The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035386	regulation of Roundabout signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.
GO:0035387	negative regulation of Roundabout signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.
GO:0035388	positive regulation of Roundabout signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.
GO:0035393	chemokine (C-X-C motif) ligand 9 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0035394	regulation of chemokine (C-X-C motif) ligand 9 production	biological_process	Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
GO:0035395	negative regulation of chemokine (C-X-C motif) ligand 9 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
GO:0035396	positive regulation of chemokine (C-X-C motif) ligand 9 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
GO:0035397	helper T cell enhancement of adaptive immune response	biological_process	Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.
GO:0035398	helper T cell enhancement of T cell mediated immune response	biological_process	Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.
GO:0035399	helper T cell enhancement of B cell mediated immune response	biological_process	Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.
GO:0035401	histone H3Y41 kinase activity	molecular_function	Catalysis of the reaction: histone H3-tyrosine (position 41) + ATP = histone H3-phosphotyrosine (position 41) + ADP. This reaction is the addition of a phosphate group to the tyrosine residue at position 41 of histone H3.
GO:0035402	histone H3T11 kinase activity	molecular_function	Catalysis of the reaction: histone H3-threonine (position 11) + ATP = histone H3-phosphothreonine (position 11) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 11 of histone H3.
GO:0035403	histone H3T6 kinase activity	molecular_function	Catalysis of the reaction: histone H3-threonine (position 6) + ATP = histone H3-phosphothreonine (position 6) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 6 of histone H3.
GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity	molecular_function	Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.
GO:0035418	protein localization to synapse	biological_process	Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0035425	autocrine signaling	biological_process	Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.
GO:0035426	extracellular matrix-cell signaling	biological_process	Any process that mediates the transfer of information between the extracellular matrix and a cell.
GO:0035429	gluconate transmembrane transport	biological_process	The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.
GO:0035430	regulation of gluconate transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.
GO:0035431	negative regulation of gluconate transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.
GO:0035432	positive regulation of gluconate transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.
GO:0035433	acetate transmembrane transport	biological_process	The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.
GO:0035434	copper ion transmembrane transport	biological_process	The directed movement of copper cation across a membrane.
GO:0035435	phosphate ion transmembrane transport	biological_process	The process in which a phosphate is transported across a membrane.
GO:0035436	triose phosphate transmembrane transport	biological_process	The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.
GO:0035437	maintenance of protein localization in endoplasmic reticulum	biological_process	Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.
GO:0035438	cyclic-di-GMP binding	molecular_function	Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate.
GO:0035439	halimadienyl-diphosphate synthase activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.
GO:0035440	tuberculosinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.
GO:0035441	cell migration involved in vasculogenesis	biological_process	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.
GO:0035442	dipeptide transmembrane transport	biological_process	The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
GO:0035443	tripeptide transmembrane transport	biological_process	The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.
GO:0035444	nickel cation transmembrane transport	biological_process	The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.
GO:0035445	borate transmembrane transport	biological_process	The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
GO:0035446	cysteine-glucosaminylinositol ligase activity	molecular_function	Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.
GO:0035447	mycothiol synthase activity	molecular_function	Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.
GO:0035448	extrinsic component of thylakoid membrane	cellular_component	The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0035449	extrinsic component of plastid thylakoid membrane	cellular_component	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0035450	extrinsic component of lumenal side of plastid thylakoid membrane	cellular_component	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.
GO:0035451	extrinsic component of stromal side of plastid thylakoid membrane	cellular_component	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.
GO:0035452	extrinsic component of plastid membrane	cellular_component	The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0035453	extrinsic component of plastid inner membrane	cellular_component	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0035454	extrinsic component of stromal side of plastid inner membrane	cellular_component	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.
GO:0035455	response to interferon-alpha	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
GO:0035456	response to interferon-beta	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
GO:0035457	cellular response to interferon-alpha	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
GO:0035458	cellular response to interferon-beta	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
GO:0035459	vesicle cargo loading	biological_process	The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
GO:0035460	L-ascorbate 6-phosphate lactonase activity	molecular_function	Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.
GO:0035461	vitamin transmembrane transport	biological_process	The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0035462	determination of left/right asymmetry in diencephalon	biological_process	The establishment of the diencephalon with respect to the left and right halves.
GO:0035469	determination of pancreatic left/right asymmetry	biological_process	Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.
GO:0035470	positive regulation of vascular wound healing	biological_process	Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GO:0035471	luteinizing hormone signaling pathway involved in ovarian follicle development	biological_process	The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.
GO:0035472	choriogonadotropin hormone receptor activity	molecular_function	Combining with the choriogonadotropin hormone to initiate a change in cell activity.
GO:0035473	lipase binding	molecular_function	Binding to a lipase.
GO:0035474	selective angioblast sprouting	biological_process	The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.
GO:0035475	angioblast cell migration involved in selective angioblast sprouting	biological_process	The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.
GO:0035476	angioblast cell migration	biological_process	The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.
GO:0035477	regulation of angioblast cell migration involved in selective angioblast sprouting	biological_process	Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.
GO:0035478	chylomicron binding	molecular_function	Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.
GO:0035479	angioblast cell migration from lateral mesoderm to midline	biological_process	The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.
GO:0035480	regulation of Notch signaling pathway involved in heart induction	biological_process	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	biological_process	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
GO:0035482	gastric motility	biological_process	The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.
GO:0035483	gastric emptying	biological_process	The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
GO:0035484	adenine/adenine mispair binding	molecular_function	Binding to a double-stranded DNA region containing an A/A mispair.
GO:0035485	adenine/guanine mispair binding	molecular_function	Binding to a double-stranded DNA region containing an A/G mispair.
GO:0035486	cytosine/cytosine mispair binding	molecular_function	Binding to a double-stranded DNA region containing a C/C mispair.
GO:0035487	thymine/thymine mispair binding	molecular_function	Binding to a double-stranded DNA region containing a T/T mispair.
GO:0035488	cytosine/thymine mispair binding	molecular_function	Binding to a double-stranded DNA region containing a C/T mispair.
GO:0035489	guanine/guanine mispair binding	molecular_function	Binding to a double-stranded DNA region containing a G/G mispair.
GO:0035490	regulation of leukotriene production involved in inflammatory response	biological_process	Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	biological_process	Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
GO:0035492	negative regulation of leukotriene production involved in inflammatory response	biological_process	Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
GO:0035493	SNARE complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035494	SNARE complex disassembly	biological_process	The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035495	regulation of SNARE complex disassembly	biological_process	Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035496	lipopolysaccharide-1,5-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.
GO:0035497	cAMP response element binding	molecular_function	Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.
GO:0035498	carnosine metabolic process	biological_process	The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).
GO:0035499	carnosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).
GO:0035500	MH2 domain binding	molecular_function	Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
GO:0035501	MH1 domain binding	molecular_function	Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.
GO:0035502	metanephric part of ureteric bud development	biological_process	The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.
GO:0035503	ureter part of ureteric bud development	biological_process	The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.
GO:0035504	regulation of myosin light chain kinase activity	biological_process	Any process that modulates the frequency, rate or extent of myosin light chain kinase activity.
GO:0035505	positive regulation of myosin light chain kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.
GO:0035506	negative regulation of myosin light chain kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.
GO:0035507	regulation of myosin-light-chain-phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.
GO:0035508	positive regulation of myosin-light-chain-phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.
GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.
GO:0035510	DNA dealkylation	biological_process	The removal of an alkyl group from one or more nucleotides within an DNA molecule.
GO:0035513	oxidative RNA demethylation	biological_process	The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.
GO:0035514	DNA demethylase activity	molecular_function	Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.
GO:0035515	oxidative RNA demethylase activity	molecular_function	Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
GO:0035516	oxidative DNA demethylase activity	molecular_function	Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.
GO:0035517	PR-DUB complex	cellular_component	A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.
GO:0035518	histone H2A monoubiquitination	biological_process	The modification of histone H2A by addition of a single ubiquitin group.
GO:0035519	protein K29-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.
GO:0035520	monoubiquitinated protein deubiquitination	biological_process	The removal of the ubiquitin group from a monoubiquitinated protein.
GO:0035521	monoubiquitinated histone deubiquitination	biological_process	The removal of the ubiquitin group from a monoubiquitinated histone protein.
GO:0035522	monoubiquitinated histone H2A deubiquitination	biological_process	The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.
GO:0035523	protein K29-linked deubiquitination	biological_process	A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.
GO:0035524	proline transmembrane transport	biological_process	The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.
GO:0035525	NF-kappaB p50/p65 complex	cellular_component	A heterodimer of NF-kappa B p50 and p65 subunits.
GO:0035526	retrograde transport, plasma membrane to Golgi	biological_process	The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.
GO:0035527	3-hydroxypropionate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.
GO:0035529	NADH pyrophosphatase activity	molecular_function	Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.
GO:0035530	chemokine (C-C motif) ligand 6 production	biological_process	The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0035531	regulation of chemokine (C-C motif) ligand 6 production	biological_process	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
GO:0035532	negative regulation of chemokine (C-C motif) ligand 6 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
GO:0035533	positive regulation of chemokine (C-C motif) ligand 6 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
GO:0035538	carbohydrate response element binding	molecular_function	Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.
GO:0035539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	molecular_function	Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.
GO:0035540	positive regulation of SNARE complex disassembly	biological_process	Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035541	negative regulation of SNARE complex disassembly	biological_process	Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035542	regulation of SNARE complex assembly	biological_process	Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035543	positive regulation of SNARE complex assembly	biological_process	Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035544	negative regulation of SNARE complex assembly	biological_process	Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
GO:0035545	determination of left/right asymmetry in nervous system	biological_process	The establishment of the nervous system with respect to the left and right halves.
GO:0035550	urease complex	cellular_component	A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).
GO:0035552	oxidative single-stranded DNA demethylation	biological_process	Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
GO:0035553	oxidative single-stranded RNA demethylation	biological_process	Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
GO:0035554	termination of Roundabout signal transduction	biological_process	The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.
GO:0035556	intracellular signal transduction	biological_process	The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GO:0035560	pheophorbidase activity	molecular_function	Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.
GO:0035561	regulation of chromatin binding	biological_process	Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
GO:0035562	negative regulation of chromatin binding	biological_process	Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
GO:0035563	positive regulation of chromatin binding	biological_process	Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
GO:0035564	regulation of kidney size	biological_process	Any process that modulates the size of a kidney.
GO:0035565	regulation of pronephros size	biological_process	Any process that modulates the size of a pronephric kidney.
GO:0035566	regulation of metanephros size	biological_process	Any process that modulates the size of a metanephric kidney.
GO:0035567	non-canonical Wnt signaling pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.
GO:0035568	N-terminal peptidyl-proline methylation	biological_process	The methylation of the N-terminal proline of proteins.
GO:0035570	N-terminal peptidyl-serine methylation	biological_process	The methylation of the N-terminal serine of proteins.
GO:0035571	N-terminal peptidyl-serine monomethylation	biological_process	The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.
GO:0035572	N-terminal peptidyl-serine dimethylation	biological_process	The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.
GO:0035573	N-terminal peptidyl-serine trimethylation	biological_process	The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.
GO:0035575	histone H4K20 demethylase activity	molecular_function	Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0035576	retinoic acid receptor signaling pathway involved in pronephric field specification	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.
GO:0035577	azurophil granule membrane	cellular_component	The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
GO:0035578	azurophil granule lumen	cellular_component	The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
GO:0035579	specific granule membrane	cellular_component	The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
GO:0035580	specific granule lumen	cellular_component	The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
GO:0035581	sequestering of extracellular ligand from receptor	biological_process	The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.
GO:0035582	sequestering of BMP in extracellular matrix	biological_process	Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.
GO:0035583	sequestering of TGFbeta in extracellular matrix	biological_process	Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.
GO:0035584	calcium-mediated signaling using intracellular calcium source	biological_process	The series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
GO:0035585	calcium-mediated signaling using extracellular calcium source	biological_process	The series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.
GO:0035588	G protein-coupled purinergic receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process.
GO:0035590	purinergic nucleotide receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035591	signaling adaptor activity	molecular_function	The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
GO:0035592	establishment of protein localization to extracellular region	biological_process	The directed movement of a protein to a specific location within the extracellular region.
GO:0035593	positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region	biological_process	Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.
GO:0035594	ganglioside binding	molecular_function	Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
GO:0035595	N-acetylglucosaminylinositol deacetylase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.
GO:0035596	methylthiotransferase activity	molecular_function	Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.
GO:0035597	N6-isopentenyladenosine methylthiotransferase activity	molecular_function	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).
GO:0035598	N6-threonylcarbomyladenosine methylthiotransferase activity	molecular_function	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).
GO:0035599	aspartic acid methylthiotransferase activity	molecular_function	Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.
GO:0035600	tRNA methylthiolation	biological_process	The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.
GO:0035601	protein deacylation	biological_process	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.
GO:0035602	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
GO:0035603	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.
GO:0035604	fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
GO:0035605	peptidyl-cysteine S-nitrosylase activity	molecular_function	Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.
GO:0035606	peptidyl-cysteine S-trans-nitrosylation	biological_process	Transfer of a nitric oxide (NO) group from one cysteine residue to another.
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.
GO:0035608	protein deglutamylation	biological_process	The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.
GO:0035609	C-terminal protein deglutamylation	biological_process	The removal of a C-terminal, gene-encoded glutamate residue from a protein.
GO:0035610	protein side chain deglutamylation	biological_process	The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.
GO:0035611	protein branching point deglutamylation	biological_process	The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.
GO:0035612	AP-2 adaptor complex binding	molecular_function	Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
GO:0035613	RNA stem-loop binding	molecular_function	Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
GO:0035614	snRNA stem-loop binding	molecular_function	Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
GO:0035615	clathrin adaptor activity	molecular_function	Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.
GO:0035616	histone H2B conserved C-terminal lysine deubiquitination	biological_process	A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
GO:0035617	stress granule disassembly	biological_process	The disaggregation of a stress granule into its constituent protein and RNA parts.
GO:0035618	root hair	cellular_component	A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.
GO:0035619	root hair tip	cellular_component	The tip portion of an outgrowth of a root epidermal cell.
GO:0035621	ER to Golgi ceramide transport	biological_process	The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
GO:0035622	intrahepatic bile duct development	biological_process	The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
GO:0035623	renal glucose absorption	biological_process	A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
GO:0035624	receptor transactivation	biological_process	The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.
GO:0035626	juvenile hormone mediated signaling pathway	biological_process	The series of molecular signals initiated by a juvenile hormone binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035627	ceramide transport	biological_process	The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
GO:0035628	cystic duct development	biological_process	The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct.
GO:0035629	N-terminal protein amino acid N-linked glycosylation	biological_process	Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein.
GO:0035630	bone mineralization involved in bone maturation	biological_process	The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.
GO:0035631	CD40 receptor complex	cellular_component	A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.
GO:0035632	mitochondrial prohibitin complex	cellular_component	A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.
GO:0035633	maintenance of blood-brain barrier	biological_process	Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.
GO:0035634	response to stilbenoid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
GO:0035635	entry of bacterium into host cell	biological_process	The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0035639	purine ribonucleoside triphosphate binding	molecular_function	Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
GO:0035640	exploration behavior	biological_process	The specific behavior of an organism in response to a novel environment or stimulus.
GO:0035641	locomotory exploration behavior	biological_process	The specific movement from place to place of an organism in response to a novel environment.
GO:0035642	histone H3R17 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.
GO:0035643	L-DOPA receptor activity	molecular_function	Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.
GO:0035644	phosphoanandamide dephosphorylation	biological_process	The process of removing one or more phosphate groups from a phosphorylated anandamide.
GO:0035645	enteric smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.
GO:0035646	endosome to melanosome transport	biological_process	The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.
GO:0035647	3-oxo-delta(4,5)-steroid 5-beta-reductase activity	molecular_function	Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H+ = a 5-beta-3-oxo-steroid + NADP+.
GO:0035648	circadian mating behavior	biological_process	The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.
GO:0035649	Nrd1 complex	cellular_component	A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.
GO:0035650	AP-1 adaptor complex binding	molecular_function	Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
GO:0035651	AP-3 adaptor complex binding	molecular_function	Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
GO:0035652	clathrin-coated vesicle cargo loading	biological_process	Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.
GO:0035653	clathrin-coated vesicle cargo loading, AP-1-mediated	biological_process	Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.
GO:0035654	clathrin-coated vesicle cargo loading, AP-3-mediated	biological_process	Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.
GO:0035655	interleukin-18-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035657	eRF1 methyltransferase complex	cellular_component	A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.
GO:0035658	Mon1-Ccz1 complex	cellular_component	A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.
GO:0035659	Wnt signaling pathway involved in wound healing, spreading of epidermal cells	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a target cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.
GO:0035660	MyD88-dependent toll-like receptor 4 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
GO:0035661	MyD88-dependent toll-like receptor 2 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.
GO:0035662	Toll-like receptor 4 binding	molecular_function	Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
GO:0035663	Toll-like receptor 2 binding	molecular_function	Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
GO:0035664	TIRAP-dependent toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0035667	TRIF-dependent toll-like receptor 4 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
GO:0035668	TRAM-dependent toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
GO:0035669	TRAM-dependent toll-like receptor 4 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
GO:0035670	plant-type ovary development	biological_process	The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.
GO:0035671	enone reductase activity	molecular_function	Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.
GO:0035672	oligopeptide transmembrane transport	biological_process	The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0035673	oligopeptide transmembrane transporter activity	molecular_function	Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0035674	tricarboxylic acid transmembrane transport	biological_process	The process in which a tricarboxylic acid is transported across a membrane.
GO:0035675	neuromast hair cell development	biological_process	The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0035676	anterior lateral line neuromast hair cell development	biological_process	The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0035677	posterior lateral line neuromast hair cell development	biological_process	The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0035678	neuromast hair cell morphogenesis	biological_process	The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
GO:0035679	anterior lateral line neuromast hair cell morphogenesis	biological_process	The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
GO:0035680	posterior lateral line neuromast hair cell morphogenesis	biological_process	The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
GO:0035681	toll-like receptor 15 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 15.
GO:0035682	toll-like receptor 21 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to toll-like receptor 21.
GO:0035683	memory T cell extravasation	biological_process	The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.
GO:0035684	helper T cell extravasation	biological_process	The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.
GO:0035685	helper T cell diapedesis	biological_process	The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
GO:0035686	sperm fibrous sheath	cellular_component	A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.
GO:0035687	T-helper 1 cell extravasation	biological_process	The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
GO:0035688	T-helper 1 cell diapedesis	biological_process	The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
GO:0035689	chemokine (C-C motif) ligand 5 signaling pathway	biological_process	The series of molecular signals initiated by chemokine CCL5 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035691	macrophage migration inhibitory factor signaling pathway	biological_process	The series of molecular signals initiated by macrophage migration inhibitory factor binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035692	macrophage migration inhibitory factor receptor complex	cellular_component	A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.
GO:0035693	NOS2-CD74 complex	cellular_component	A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.
GO:0035694	mitochondrial protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
GO:0035695	mitophagy by induced vacuole formation	biological_process	The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
GO:0035696	monocyte extravasation	biological_process	The migration of a monocyte from the blood vessels into the surrounding tissue.
GO:0035697	CD8-positive, alpha-beta T cell extravasation	biological_process	The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.
GO:0035698	CD8-positive, alpha-beta cytotoxic T cell extravasation	biological_process	The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.
GO:0035699	T-helper 17 cell extravasation	biological_process	The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.
GO:0035700	astrocyte chemotaxis	biological_process	The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0035701	hematopoietic stem cell migration	biological_process	The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
GO:0035702	monocyte homeostasis	biological_process	The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0035703	monocyte migration into blood stream	biological_process	The movement of a monocyte from the bone marrow to the blood stream.
GO:0035704	helper T cell chemotaxis	biological_process	The directed movement of a helper T cell in response to an external stimulus.
GO:0035705	T-helper 17 cell chemotaxis	biological_process	The directed movement of a T-helper 17 cell in response to an external stimulus.
GO:0035706	T-helper 1 cell chemotaxis	biological_process	The directed movement of a T-helper 1 cell in response to an external stimulus.
GO:0035707	T-helper 2 cell chemotaxis	biological_process	The directed movement of a T-helper 2 cell in response to an external stimulus.
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	biological_process	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).
GO:0035709	memory T cell activation	biological_process	The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0035710	CD4-positive, alpha-beta T cell activation	biological_process	The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0035711	T-helper 1 cell activation	biological_process	The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0035712	T-helper 2 cell activation	biological_process	The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0035713	response to nitrogen dioxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
GO:0035714	cellular response to nitrogen dioxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
GO:0035715	chemokine (C-C motif) ligand 2 binding	molecular_function	Binding to chemokine (C-C motif) ligand 2.
GO:0035716	chemokine (C-C motif) ligand 12 binding	molecular_function	Binding to chemokine (C-C motif) ligand 12.
GO:0035717	chemokine (C-C motif) ligand 7 binding	molecular_function	Binding to chemokine (C-C motif) ligand 7.
GO:0035718	macrophage migration inhibitory factor binding	molecular_function	Binding to the cytokine, macrophage migration inhibitory factor.
GO:0035719	tRNA import into nucleus	biological_process	The directed movement of tRNA from the cytoplasm to the nucleus.
GO:0035720	intraciliary anterograde transport	biological_process	The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
GO:0035721	intraciliary retrograde transport	biological_process	The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
GO:0035722	interleukin-12-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-12 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035723	interleukin-15-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035724	CD24 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.
GO:0035725	sodium ion transmembrane transport	biological_process	A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0035726	common myeloid progenitor cell proliferation	biological_process	The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.
GO:0035727	lysophosphatidic acid binding	molecular_function	Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.
GO:0035728	response to hepatocyte growth factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
GO:0035729	cellular response to hepatocyte growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
GO:0035730	S-nitrosoglutathione binding	molecular_function	Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.
GO:0035731	dinitrosyl-iron complex binding	molecular_function	Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.
GO:0035732	nitric oxide storage	biological_process	The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.
GO:0035733	hepatic stellate cell activation	biological_process	A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.
GO:0035735	intraciliary transport involved in cilium assembly	biological_process	The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
GO:0035736	cell proliferation involved in compound eye morphogenesis	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.
GO:0035738	envenomation resulting in modulation of process in another organism	biological_process	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.
GO:0035739	CD4-positive, alpha-beta T cell proliferation	biological_process	The expansion of a CD4-positive, alpha-beta T cell population by cell division.
GO:0035740	CD8-positive, alpha-beta T cell proliferation	biological_process	The expansion of a CD8-positive, alpha-beta T cell population by cell division.
GO:0035741	activated CD4-positive, alpha-beta T cell proliferation	biological_process	The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.
GO:0035742	activated CD8-positive, alpha-beta T cell proliferation	biological_process	The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	biological_process	Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.
GO:0035744	T-helper 1 cell cytokine production	biological_process	Any process that contributes to cytokine production by a T-helper 1 cell.
GO:0035745	T-helper 2 cell cytokine production	biological_process	Any process that contributes to cytokine production by a T-helper 2 cell.
GO:0035746	granzyme A production	biological_process	The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0035747	natural killer cell chemotaxis	biological_process	The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0035748	myelin sheath abaxonal region	cellular_component	The region of the myelin sheath furthest from the axon.
GO:0035749	myelin sheath adaxonal region	cellular_component	The region of the myelin sheath nearest to the axon.
GO:0035750	protein localization to myelin sheath abaxonal region	biological_process	Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.
GO:0035751	regulation of lysosomal lumen pH	biological_process	Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
GO:0035752	lysosomal lumen pH elevation	biological_process	Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
GO:0035753	maintenance of DNA trinucleotide repeats	biological_process	Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.
GO:0035754	B cell chemotaxis	biological_process	The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0035755	cardiolipin hydrolase activity	molecular_function	Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).
GO:0035756	transepithelial migration of symbiont in host	biological_process	The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0035757	chemokine (C-C motif) ligand 19 binding	molecular_function	Binding to chemokine (C-C motif) ligand 19.
GO:0035758	chemokine (C-C motif) ligand 21 binding	molecular_function	Binding to chemokine (C-C motif) ligand 21.
GO:0035759	mesangial cell-matrix adhesion	biological_process	The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.
GO:0035760	cytoplasmic polyadenylation-dependent rRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.
GO:0035761	dorsal motor nucleus of vagus nerve maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.
GO:0035762	dorsal motor nucleus of vagus nerve morphogenesis	biological_process	The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.
GO:0035763	dorsal motor nucleus of vagus nerve structural organization	biological_process	The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.
GO:0035764	dorsal motor nucleus of vagus nerve formation	biological_process	The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.
GO:0035765	motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation	biological_process	The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.
GO:0035766	cell chemotaxis to fibroblast growth factor	biological_process	The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).
GO:0035767	endothelial cell chemotaxis	biological_process	The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	biological_process	The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).
GO:0035769	B cell chemotaxis across high endothelial venule	biological_process	The movement of a B cell to cross a high endothelial venule in response to an external stimulus.
GO:0035770	ribonucleoprotein granule	cellular_component	A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
GO:0035771	interleukin-4-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035772	interleukin-13-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-13 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	biological_process	The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	biological_process	Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
GO:0035775	pronephric glomerulus morphogenesis	biological_process	The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.
GO:0035776	pronephric proximal tubule development	biological_process	The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
GO:0035777	pronephric distal tubule development	biological_process	The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
GO:0035778	pronephric nephron tubule epithelial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.
GO:0035779	angioblast cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).
GO:0035780	CD80 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.
GO:0035781	CD86 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.
GO:0035782	mature natural killer cell chemotaxis	biological_process	The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.
GO:0035783	CD4-positive, alpha-beta T cell costimulation	biological_process	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
GO:0035785	intracellular nickel ion homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell.
GO:0035787	cell migration involved in kidney development	biological_process	The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.
GO:0035788	cell migration involved in metanephros development	biological_process	The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.
GO:0035789	metanephric mesenchymal cell migration	biological_process	The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.
GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway	biological_process	The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0035792	host cell postsynaptic membrane	cellular_component	A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	biological_process	Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration resulting from the platelet-derived growth factor receptor-beta signaling pathway.
GO:0035794	positive regulation of mitochondrial membrane permeability	biological_process	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
GO:0035795	negative regulation of mitochondrial membrane permeability	biological_process	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
GO:0035796	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	cellular_component	A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
GO:0035797	tellurite methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).
GO:0035798	2-alkenal reductase (NADP+) activity	molecular_function	Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.
GO:0035799	ureter maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.
GO:0035800	deubiquitinase activator activity	molecular_function	Binds to and increases the activity of a deubiquitinase.
GO:0035801	adrenal cortex development	biological_process	The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).
GO:0035802	adrenal cortex formation	biological_process	The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).
GO:0035803	egg coat formation	biological_process	Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
GO:0035804	structural constituent of egg coat	molecular_function	The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
GO:0035805	egg coat	cellular_component	A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
GO:0035806	perturbation of blood coagulation in another organism	biological_process	The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
GO:0035807	induction of blood coagulation in another organism	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
GO:0035808	meiotic recombination initiation complex	cellular_component	A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins.
GO:0035809	regulation of urine volume	biological_process	Any process that modulates the amount of urine excreted from the body over a unit of time.
GO:0035810	positive regulation of urine volume	biological_process	Any process that increases the amount of urine excreted from the body over a unit of time.
GO:0035811	negative regulation of urine volume	biological_process	Any process that decreases the amount of urine excreted from the body over a unit of time.
GO:0035812	renal sodium excretion	biological_process	The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
GO:0035813	regulation of renal sodium excretion	biological_process	Any process that modulates the amount of sodium excreted in urine over a unit of time.
GO:0035814	negative regulation of renal sodium excretion	biological_process	Any process that decreases the amount of sodium excreted in urine over a unit of time.
GO:0035815	positive regulation of renal sodium excretion	biological_process	Any process that increases the amount of sodium excreted in urine over a unit of time.
GO:0035817	renal sodium ion absorption involved in negative regulation of renal sodium excretion	biological_process	Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time.
GO:0035818	positive regulation of urine volume by pressure natriuresis	biological_process	An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.
GO:0035819	positive regulation of renal sodium excretion by pressure natriuresis	biological_process	An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.
GO:0035820	negative regulation of renal sodium excretion by angiotensin	biological_process	The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.
GO:0035821	modulation of process of another organism	biological_process	The process in which an organism effects a change in the structure or processes of another organism.
GO:0035822	gene conversion	biological_process	A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor.
GO:0035823	short tract gene conversion	biological_process	A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor.
GO:0035824	long tract gene conversion	biological_process	A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor.
GO:0035825	homologous recombination	biological_process	A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules.
GO:0035830	palmatine metabolic process	biological_process	The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants.
GO:0035831	palmatine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.
GO:0035832	berbamunine metabolic process	biological_process	The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.
GO:0035833	berbamunine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.
GO:0035834	indole alkaloid metabolic process	biological_process	The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.
GO:0035835	indole alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.
GO:0035836	ergot alkaloid metabolic process	biological_process	The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid.
GO:0035837	ergot alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an ergot alkaloid.
GO:0035838	growing cell tip	cellular_component	The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.
GO:0035839	non-growing cell tip	cellular_component	A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
GO:0035840	old growing cell tip	cellular_component	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
GO:0035841	new growing cell tip	cellular_component	A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.
GO:0035842	old cell tip after activation of bipolar cell growth	cellular_component	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
GO:0035843	endonuclear canal	cellular_component	A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope.
GO:0035844	cloaca development	biological_process	The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.
GO:0035845	photoreceptor cell outer segment organization	biological_process	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
GO:0035846	oviduct epithelium development	biological_process	The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.
GO:0035847	uterine epithelium development	biological_process	The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
GO:0035848	oviduct morphogenesis	biological_process	The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
GO:0035849	nephric duct elongation	biological_process	The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney.
GO:0035850	epithelial cell differentiation involved in kidney development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.
GO:0035851	Krueppel-associated box domain binding	molecular_function	Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.
GO:0035852	horizontal cell localization	biological_process	Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.
GO:0035853	chromosome passenger complex localization to spindle midzone	biological_process	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
GO:0035854	eosinophil fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.
GO:0035855	megakaryocyte development	biological_process	The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
GO:0035857	eosinophil fate specification	biological_process	The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
GO:0035858	eosinophil fate determination	biological_process	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0035859	Seh1-associated complex	cellular_component	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.
GO:0035861	site of double-strand break	cellular_component	A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
GO:0035862	dITP metabolic process	biological_process	The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
GO:0035863	dITP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
GO:0035864	response to potassium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
GO:0035865	cellular response to potassium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
GO:0035866	alphav-beta3 integrin-PKCalpha complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.
GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.
GO:0035868	alphav-beta3 integrin-HMGB1 complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.
GO:0035869	ciliary transition zone	cellular_component	A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
GO:0035870	dITP diphosphatase activity	molecular_function	Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.
GO:0035871	protein K11-linked deubiquitination	biological_process	A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number.
GO:0035873	lactate transmembrane transport	biological_process	The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
GO:0035874	cellular response to copper ion starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
GO:0035875	maintenance of meiotic sister chromatid cohesion, centromeric	biological_process	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
GO:0035876	maintenance of meiotic sister chromatid cohesion, arms	biological_process	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
GO:0035877	death effector domain binding	molecular_function	Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).
GO:0035878	nail development	biological_process	The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.
GO:0035879	plasma membrane lactate transport	biological_process	The directed movement of lactate across a plasma membrane.
GO:0035880	embryonic nail plate morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
GO:0035881	amacrine cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
GO:0035882	defecation rhythm	biological_process	The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.
GO:0035883	enteroendocrine cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.
GO:0035884	arabinan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.
GO:0035885	exochitinase activity	molecular_function	Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.
GO:0035886	vascular associated smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
GO:0035887	aortic smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.
GO:0035888	isoguanine deaminase activity	molecular_function	Catalysis of the reaction: isoguanine + H2O = xanthine + NH3.
GO:0035889	otolith tethering	biological_process	The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.
GO:0035891	exit from host cell	biological_process	The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0035892	perturbation of platelet aggregation in another organism	biological_process	The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GO:0035893	suppression of platelet aggregation in another organism	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.
GO:0035894	induction of platelet aggregation in another organism	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.
GO:0035895	modulation of mast cell degranulation in another organism	biological_process	Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
GO:0035896	positive regulation of mast cell degranulation in another organism	biological_process	Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.
GO:0035898	parathyroid hormone secretion	biological_process	The regulated release of parathyroid hormone into the circulatory system.
GO:0035899	suppression of blood coagulation in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
GO:0035900	response to isolation stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
GO:0035901	cellular response to isolation stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
GO:0035902	response to immobilization stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
GO:0035903	cellular response to immobilization stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
GO:0035904	aorta development	biological_process	The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.
GO:0035905	ascending aorta development	biological_process	The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
GO:0035906	descending aorta development	biological_process	The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
GO:0035907	dorsal aorta development	biological_process	The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
GO:0035908	ventral aorta development	biological_process	The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
GO:0035909	aorta morphogenesis	biological_process	The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
GO:0035910	ascending aorta morphogenesis	biological_process	The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
GO:0035911	descending aorta morphogenesis	biological_process	The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
GO:0035912	dorsal aorta morphogenesis	biological_process	The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
GO:0035913	ventral aorta morphogenesis	biological_process	The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
GO:0035914	skeletal muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
GO:0035915	pore formation in membrane of another organism	biological_process	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism.
GO:0035916	modulation of calcium channel activity in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism.
GO:0035917	negative regulation of calcium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.
GO:0035918	negative regulation of voltage-gated calcium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0035919	negative regulation of low voltage-gated calcium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.
GO:0035920	negative regulation of high voltage-gated calcium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
GO:0035921	desmosome disassembly	biological_process	The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
GO:0035922	foramen ovale closure	biological_process	The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
GO:0035923	flurbiprofen binding	molecular_function	Binding to flurbiprofen.
GO:0035924	cellular response to vascular endothelial growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
GO:0035925	mRNA 3'-UTR AU-rich region binding	molecular_function	Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.
GO:0035927	RNA import into mitochondrion	biological_process	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix.
GO:0035928	rRNA import into mitochondrion	biological_process	The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix.
GO:0035929	steroid hormone secretion	biological_process	The regulated release of any steroid that acts as a hormone into the circulatory system.
GO:0035930	corticosteroid hormone secretion	biological_process	The regulated release of any corticosteroid hormone into the circulatory system.
GO:0035931	mineralocorticoid secretion	biological_process	The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.
GO:0035932	aldosterone secretion	biological_process	The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
GO:0035933	glucocorticoid secretion	biological_process	The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
GO:0035934	corticosterone secretion	biological_process	The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
GO:0035935	androgen secretion	biological_process	The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.
GO:0035936	testosterone secretion	biological_process	The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.
GO:0035937	estrogen secretion	biological_process	The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.
GO:0035938	estradiol secretion	biological_process	The regulated release of estradiol into the circulatory system.
GO:0035939	microsatellite binding	molecular_function	Binding to a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem.
GO:0035941	androstenedione secretion	biological_process	The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.
GO:0035942	dehydroepiandrosterone secretion	biological_process	The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.
GO:0035943	estrone secretion	biological_process	The regulated release of estrone into the circulatory system.
GO:0035944	perforin production	biological_process	The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0035945	mitochondrial ncRNA surveillance	biological_process	The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.
GO:0035946	mitochondrial mRNA surveillance	biological_process	The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.
GO:0035962	response to interleukin-13	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
GO:0035963	cellular response to interleukin-13	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
GO:0035964	COPI-coated vesicle budding	biological_process	The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
GO:0035965	cardiolipin acyl-chain remodeling	biological_process	Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.
GO:0035966	response to topologically incorrect protein	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
GO:0035967	cellular response to topologically incorrect protein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
GO:0035970	peptidyl-threonine dephosphorylation	biological_process	The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
GO:0035971	peptidyl-histidine dephosphorylation	biological_process	The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.
GO:0035973	aggrephagy	biological_process	Selective degradation of protein aggregates by macroautophagy.
GO:0035974	meiotic spindle pole body	cellular_component	The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.
GO:0035975	carbamoyl phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
GO:0035976	transcription factor AP-1 complex	cellular_component	A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.
GO:0035977	protein deglycosylation involved in glycoprotein catabolic process	biological_process	The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.
GO:0035979	histone H2AXS139 kinase activity	molecular_function	Catalysis of the reaction: histone H2AX-serine (position 139) + ATP = histone H2AX-phosphoserine (position 139) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 139 of histone variant H2AX.
GO:0035981	tongue muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.
GO:0035983	response to trichostatin A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
GO:0035984	cellular response to trichostatin A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
GO:0035985	senescence-associated heterochromatin focus	cellular_component	A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
GO:0035987	endodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
GO:0035988	chondrocyte proliferation	biological_process	The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
GO:0035989	tendon development	biological_process	The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.
GO:0035990	tendon cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
GO:0035991	nitric oxide sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO).
GO:0035992	tendon formation	biological_process	The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.
GO:0035993	deltoid tuberosity development	biological_process	The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.
GO:0035994	response to muscle stretch	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.
GO:0035995	detection of muscle stretch	biological_process	The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.
GO:0035996	rhabdomere microvillus	cellular_component	Thin cylindrical membrane-covered projection on the surface of a rhabdomere.
GO:0035997	rhabdomere microvillus membrane	cellular_component	The portion of the plasma membrane surrounding a microvillus of a rhabdomere.
GO:0035998	7,8-dihydroneopterin 3'-triphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate.
GO:0035999	tetrahydrofolate interconversion	biological_process	The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
GO:0036000	mucocyst	cellular_component	A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.
GO:0036001	'de novo' pyridoxal 5'-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.
GO:0036002	pre-mRNA binding	molecular_function	Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0036004	GAF domain binding	molecular_function	Binding to a GAF protein domain.
GO:0036005	response to macrophage colony-stimulating factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
GO:0036007	scintillon	cellular_component	A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.
GO:0036008	sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.
GO:0036009	protein-glutamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.
GO:0036010	protein localization to endosome	biological_process	A process in which a protein is transported to, or maintained in, a location within an endosome.
GO:0036011	imaginal disc-derived leg segmentation	biological_process	Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.
GO:0036012	cyanelle inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma.
GO:0036013	cyanelle outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.
GO:0036014	cyanelle intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer.
GO:0036015	response to interleukin-3	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
GO:0036016	cellular response to interleukin-3	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
GO:0036017	response to erythropoietin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.
GO:0036018	cellular response to erythropoietin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.
GO:0036019	endolysosome	cellular_component	An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.
GO:0036020	endolysosome membrane	cellular_component	The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.
GO:0036021	endolysosome lumen	cellular_component	The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.
GO:0036022	limb joint morphogenesis	biological_process	The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.
GO:0036023	embryonic skeletal limb joint morphogenesis	biological_process	The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.
GO:0036024	protein C inhibitor-TMPRSS7 complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.
GO:0036025	protein C inhibitor-TMPRSS11E complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E.
GO:0036026	protein C inhibitor-PLAT complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator.
GO:0036027	protein C inhibitor-PLAU complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.
GO:0036028	protein C inhibitor-thrombin complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin.
GO:0036029	protein C inhibitor-KLK3 complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen.
GO:0036030	protein C inhibitor-plasma kallikrein complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.
GO:0036031	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	biological_process	The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.
GO:0036032	neural crest cell delamination	biological_process	The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
GO:0036033	mediator complex binding	molecular_function	Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
GO:0036034	mediator complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
GO:0036035	osteoclast development	biological_process	The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
GO:0036036	cardiac neural crest cell delamination	biological_process	The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.
GO:0036037	CD8-positive, alpha-beta T cell activation	biological_process	The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0036038	MKS complex	cellular_component	A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.
GO:0036039	curcumin metabolic process	biological_process	The chemical reactions and pathways involving the polyphenol, curcumin.
GO:0036040	curcumin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.
GO:0036041	long-chain fatty acid binding	molecular_function	Binding to a long-chain fatty acid. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0036042	long-chain fatty acyl-CoA binding	molecular_function	Binding to a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0036046	protein demalonylation	biological_process	The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.
GO:0036047	peptidyl-lysine demalonylation	biological_process	The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.
GO:0036048	protein desuccinylation	biological_process	The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.
GO:0036049	peptidyl-lysine desuccinylation	biological_process	The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.
GO:0036050	peptidyl-lysine succinylation	biological_process	The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.
GO:0036051	protein localization to trailing edge	biological_process	A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.
GO:0036052	protein localization to uropod	biological_process	A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell.
GO:0036053	glomerular endothelium fenestra	cellular_component	A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.
GO:0036054	protein-malonyllysine demalonylase activity	molecular_function	Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.
GO:0036055	protein-succinyllysine desuccinylase activity	molecular_function	Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0036056	filtration diaphragm	cellular_component	A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
GO:0036057	slit diaphragm	cellular_component	A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
GO:0036058	filtration diaphragm assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
GO:0036059	nephrocyte diaphragm assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.
GO:0036060	slit diaphragm assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
GO:0036061	muscle cell chemotaxis toward tendon cell	biological_process	The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.
GO:0036062	presynaptic periactive zone	cellular_component	A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.
GO:0036063	acroblast	cellular_component	A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle.
GO:0036064	ciliary basal body	cellular_component	A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
GO:0036065	fucosylation	biological_process	The covalent attachment of a fucosyl group to an acceptor molecule.
GO:0036066	protein O-linked fucosylation	biological_process	The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.
GO:0036067	light-dependent chlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.
GO:0036068	light-independent chlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.
GO:0036069	light-dependent bacteriochlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
GO:0036070	light-independent bacteriochlorophyll biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
GO:0036071	N-glycan fucosylation	biological_process	The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.
GO:0036072	direct ossification	biological_process	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.
GO:0036073	perichondral ossification	biological_process	Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.
GO:0036074	metaplastic ossification	biological_process	Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.
GO:0036075	replacement ossification	biological_process	Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.
GO:0036076	ligamentous ossification	biological_process	Ossification wherein bone tissue forms within ligamentous tissue.
GO:0036077	intratendonous ossification	biological_process	Ossification wherein bone tissue forms within tendonous tissue.
GO:0036078	minus-end specific microtubule depolymerization	biological_process	The removal of tubulin heterodimers from the minus end of a microtubule.
GO:0036080	purine nucleotide-sugar transmembrane transporter activity	molecular_function	Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0036081	extracellular ammonia-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.
GO:0036082	extracellular phenylacetaldehyde-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.
GO:0036084	GDP-fucose import into endoplasmic reticulum lumen	biological_process	The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
GO:0036085	GDP-fucose import into Golgi lumen	biological_process	The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
GO:0036086	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
GO:0036087	glutathione synthase complex	cellular_component	A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer.
GO:0036088	D-serine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
GO:0036089	cleavage furrow formation	biological_process	Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.
GO:0036090	cleavage furrow ingression	biological_process	Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
GO:0036093	germ cell proliferation	biological_process	The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
GO:0036094	small molecule binding	molecular_function	Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.
GO:0036098	male germ-line stem cell population maintenance	biological_process	The process by which an organism or tissue maintains a population of male germ-line stem cells.
GO:0036099	female germ-line stem cell population maintenance	biological_process	The process by which an organism or tissue maintains a population of female germ-line stem cells.
GO:0036100	leukotriene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
GO:0036101	leukotriene B4 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
GO:0036102	leukotriene B4 metabolic process	biological_process	The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
GO:0036103	Kdo2-lipid A metabolic process	biological_process	The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.
GO:0036104	Kdo2-lipid A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.
GO:0036105	peroxisome membrane class-1 targeting sequence binding	molecular_function	Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
GO:0036106	peroxisome membrane class-2 targeting sequence binding	molecular_function	Binding to a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner.
GO:0036107	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process	biological_process	The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
GO:0036108	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
GO:0036109	alpha-linolenic acid metabolic process	biological_process	The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
GO:0036110	cellular response to inositol starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.
GO:0036111	very long-chain fatty-acyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
GO:0036112	medium-chain fatty-acyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0036113	very long-chain fatty-acyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
GO:0036114	medium-chain fatty-acyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0036115	fatty-acyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
GO:0036116	long-chain fatty-acyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
GO:0036117	hyaluranon cable	cellular_component	A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
GO:0036118	hyaluranon cable assembly	biological_process	A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
GO:0036119	response to platelet-derived growth factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
GO:0036120	cellular response to platelet-derived growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
GO:0036121	double-stranded DNA helicase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.
GO:0036122	BMP binding	molecular_function	Binding to a member of the bone morphogenetic protein (BMP) family.
GO:0036123	histone H3-K9 dimethylation	biological_process	The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone.
GO:0036124	histone H3-K9 trimethylation	biological_process	The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone.
GO:0036125	fatty acid beta-oxidation multienzyme complex	cellular_component	A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).
GO:0036126	sperm flagellum	cellular_component	A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
GO:0036127	3-sulfino-L-alanine binding	molecular_function	Binding to 3-sulfino-L-alanine (cysteine sulfinate).
GO:0036128	CatSper complex	cellular_component	A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.
GO:0036130	prostaglandin H2 endoperoxidase reductase activity	molecular_function	Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).
GO:0036131	prostaglandin D2 11-ketoreductase activity	molecular_function	Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+.
GO:0036132	13-prostaglandin reductase activity	molecular_function	Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.
GO:0036133	11-hydroxythromboxane B2 dehydrogenase activity	molecular_function	Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.
GO:0036134	12-hydroxyheptadecatrienoic acid synthase activity	molecular_function	Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).
GO:0036135	Schwann cell migration	biological_process	The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.
GO:0036136	kynurenine-oxaloacetate transaminase activity	molecular_function	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate.
GO:0036137	kynurenine aminotransferase activity	molecular_function	Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid.
GO:0036138	peptidyl-histidine hydroxylation	biological_process	The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.
GO:0036139	peptidyl-histidine dioxygenase activity	molecular_function	Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2.
GO:0036140	[protein]-asparagine 3-dioxygenase activity	molecular_function	Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.
GO:0036141	L-phenylalanine-oxaloacetate transaminase activity	molecular_function	Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate.
GO:0036143	kringle domain binding	molecular_function	Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
GO:0036145	dendritic cell homeostasis	biological_process	The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0036146	cellular response to mycotoxin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
GO:0036147	rumination	biological_process	A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.
GO:0036148	phosphatidylglycerol acyl-chain remodeling	biological_process	Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
GO:0036149	phosphatidylinositol acyl-chain remodeling	biological_process	Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
GO:0036150	phosphatidylserine acyl-chain remodeling	biological_process	Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
GO:0036151	phosphatidylcholine acyl-chain remodeling	biological_process	Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
GO:0036152	phosphatidylethanolamine acyl-chain remodeling	biological_process	Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
GO:0036153	triglyceride acyl-chain remodeling	biological_process	Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.
GO:0036154	diacylglycerol acyl-chain remodeling	biological_process	Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.
GO:0036155	acylglycerol acyl-chain remodeling	biological_process	Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.
GO:0036156	inner dynein arm	cellular_component	Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
GO:0036157	outer dynein arm	cellular_component	Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
GO:0036158	outer dynein arm assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
GO:0036159	inner dynein arm assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
GO:0036160	melanocyte-stimulating hormone secretion	biological_process	The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.
GO:0036161	calcitonin secretion	biological_process	The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.
GO:0036162	oxytocin production	biological_process	The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.
GO:0036163	3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity	molecular_function	Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.
GO:0036164	cell-abiotic substrate adhesion	biological_process	The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.
GO:0036165	invasive growth in response to heat	biological_process	The growth of colonies in filamentous chains of cells as a result of an increase in temperature.
GO:0036166	phenotypic switching	biological_process	A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
GO:0036167	phenotypic switching in response to host	biological_process	A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
GO:0036168	filamentous growth of a population of unicellular organisms in response to heat	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.
GO:0036169	3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity	molecular_function	Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.
GO:0036170	filamentous growth of a population of unicellular organisms in response to starvation	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
GO:0036171	filamentous growth of a population of unicellular organisms in response to chemical stimulus	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
GO:0036172	thiamine salvage	biological_process	A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.
GO:0036173	thiosulfate binding	molecular_function	Binding to a thiosulfate, a sulfur oxide that has formula O3S2.
GO:0036174	butane monooxygenase activity	molecular_function	Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.
GO:0036175	ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor	molecular_function	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin.
GO:0036176	response to neutral pH	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0036177	filamentous growth of a population of unicellular organisms in response to pH	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0036178	filamentous growth of a population of unicellular organisms in response to neutral pH	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
GO:0036179	osteoclast maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.
GO:0036180	filamentous growth of a population of unicellular organisms in response to biotic stimulus	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
GO:0036181	protein localization to linear element	biological_process	A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.
GO:0036182	asperthecin metabolic process	biological_process	The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
GO:0036183	asperthecin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
GO:0036184	asperthecin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
GO:0036185	13-lipoxin reductase activity	molecular_function	Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+.
GO:0036186	early phagosome membrane	cellular_component	The lipid bilayer surrounding an early phagosome.
GO:0036187	cell growth mode switching, budding to filamentous	biological_process	The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.
GO:0036188	abieta-7,13-dien-18-al dehydrogenase activity	molecular_function	Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.
GO:0036189	abieta-7,13-diene hydroxylase activity	molecular_function	Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.
GO:0036190	indole-2-monooxygenase activity	molecular_function	Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O.
GO:0036191	indolin-2-one monooxygenase activity	molecular_function	Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O.
GO:0036192	3-hydroxyindolin-2-one monooxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.
GO:0036193	2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.
GO:0036194	muscle cell projection	cellular_component	A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
GO:0036195	muscle cell projection membrane	cellular_component	The portion of the plasma membrane surrounding a muscle cell projection.
GO:0036196	zymosterol metabolic process	biological_process	The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
GO:0036197	zymosterol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
GO:0036198	dTMP salvage	biological_process	Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.
GO:0036199	cholest-4-en-3-one 26-monooxygenase activity	molecular_function	Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
GO:0036200	3-ketosteroid 9-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.
GO:0036201	ent-isokaurene C2-hydroxylase activity	molecular_function	Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.
GO:0036202	ent-cassa-12,15-diene 11-hydroxylase activity	molecular_function	Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.
GO:0036203	taxoid 14-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.
GO:0036204	abieta-7,13-dien-18-ol hydroxylase activity	molecular_function	Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.
GO:0036205	histone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
GO:0036209	9beta-pimara-7,15-diene oxidase activity	molecular_function	Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].
GO:0036210	protein modification process in another organism	biological_process	The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0036211	protein modification process	biological_process	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0036213	contractile ring contraction	biological_process	The process of an actomyosin ring getting smaller in diameter.
GO:0036214	contractile ring localization	biological_process	The process in which a contractile ring is positioned or maintained in a specific location.
GO:0036215	response to stem cell factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
GO:0036216	cellular response to stem cell factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
GO:0036217	dGTP diphosphatase activity	molecular_function	Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.
GO:0036218	dTTP diphosphatase activity	molecular_function	Catalysis of the reaction: dTTP + H2O = dTMP + H+ + diphosphate.
GO:0036219	GTP diphosphatase activity	molecular_function	Catalysis of the reaction: GTP + H2O = GMP + H+ + diphosphate.
GO:0036220	ITP diphosphatase activity	molecular_function	Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.
GO:0036221	UTP diphosphatase activity	molecular_function	Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.
GO:0036222	XTP diphosphatase activity	molecular_function	Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.
GO:0036223	cellular response to adenine starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.
GO:0036224	pairing center	cellular_component	A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.
GO:0036225	cellular response to vitamin B1 starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).
GO:0036227	mitotic G2 cell cycle arrest in response to glucose starvation	biological_process	The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.
GO:0036228	protein localization to nuclear inner membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane.
GO:0036230	granulocyte activation	biological_process	The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0036234	deglucuronidation	biological_process	The removal of glucuronic acid from a conjugated substrate.
GO:0036235	acyl deglucuronidation	biological_process	The removal of glucuronic acid from an acyl-glucuronide.
GO:0036236	acyl glucuronidation	biological_process	The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).
GO:0036237	acyl-glucuronidase activity	molecular_function	Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.
GO:0036238	gallate dioxygenase activity	molecular_function	Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.
GO:0036239	taxoid 7beta-hydroxylase activity	molecular_function	Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O and 2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O.
GO:0036240	septal periplasm	cellular_component	The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.
GO:0036241	glutamate catabolic process to 4-hydroxybutyrate	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.
GO:0036242	glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity	biological_process	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.
GO:0036243	succinate-semialdehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.
GO:0036244	cellular response to neutral pH	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0036245	cellular response to menadione	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.
GO:0036246	phytochelatin 2 import into vacuole	biological_process	The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
GO:0036247	phytochelatin 3 import into vacuole	biological_process	The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
GO:0036248	phytochelatin 4 import into vacuole	biological_process	The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
GO:0036249	cadmium ion import into vacuole	biological_process	The directed movement of cadmium ions into the vacuole.
GO:0036250	peroxisome transport along microtubule	biological_process	The directed movement of a peroxisome along a microtubule, mediated by motor proteins.
GO:0036255	response to methylamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
GO:0036256	cellular response to methylamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
GO:0036257	multivesicular body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
GO:0036258	multivesicular body assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
GO:0036259	aerobic raffinose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.
GO:0036260	RNA capping	biological_process	The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts.
GO:0036261	7-methylguanosine cap hypermethylation	biological_process	Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.
GO:0036262	granulysin production	biological_process	The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0036265	RNA (guanine-N7)-methylation	biological_process	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.
GO:0036266	Cdc48p-Npl4p-Vms1p AAA ATPase complex	cellular_component	A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p.
GO:0036267	invasive filamentous growth	biological_process	The growth of colonies in filamentous chains of cells into a substrate.
GO:0036268	swimming	biological_process	Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.
GO:0036269	swimming behavior	biological_process	The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.
GO:0036270	response to diuretic	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
GO:0036271	response to methylphenidate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
GO:0036272	response to gemcitabine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
GO:0036273	response to statin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
GO:0036274	response to lapatinib	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
GO:0036275	response to 5-fluorouracil	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
GO:0036276	response to antidepressant	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
GO:0036277	response to anticonvulsant	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
GO:0036279	positive regulation of protein export from nucleus in response to glucose starvation	biological_process	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.
GO:0036280	cellular response to L-canavanine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.
GO:0036284	tubulobulbar complex	cellular_component	Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.
GO:0036285	SAGA complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.
GO:0036286	eisosome filament	cellular_component	A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.
GO:0036287	response to iloperidone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
GO:0036288	response to ximelagatran	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
GO:0036289	peptidyl-serine autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.
GO:0036290	protein trans-autophosphorylation	biological_process	The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
GO:0036291	protein cis-autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own amino acid residues.
GO:0036292	DNA rewinding	biological_process	The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.
GO:0036293	response to decreased oxygen levels	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
GO:0036294	cellular response to decreased oxygen levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
GO:0036295	cellular response to increased oxygen levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
GO:0036296	response to increased oxygen levels	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
GO:0036297	interstrand cross-link repair	biological_process	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
GO:0036298	recombinational interstrand cross-link repair	biological_process	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.
GO:0036299	non-recombinational interstrand cross-link repair	biological_process	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.
GO:0036300	B cell receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.
GO:0036301	macrophage colony-stimulating factor production	biological_process	The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0036302	atrioventricular canal development	biological_process	The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.
GO:0036303	lymph vessel morphogenesis	biological_process	The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.
GO:0036304	umbilical cord morphogenesis	biological_process	The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.
GO:0036305	ameloblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.
GO:0036306	embryonic heart tube elongation	biological_process	The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
GO:0036307	23S rRNA (adenine(2030)-N(6))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.
GO:0036308	16S rRNA (guanine(1516)-N(2))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.
GO:0036309	protein localization to M-band	biological_process	Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.
GO:0036310	ATP-dependent DNA/DNA annealing activity	molecular_function	An ATP-dependent activity that facilitates the formation of a complementary double-stranded DNA molecule.
GO:0036311	chitin disaccharide deacetylase activity	molecular_function	Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate.
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	molecular_function	Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.
GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding	molecular_function	Binding to the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
GO:0036314	response to sterol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
GO:0036315	cellular response to sterol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
GO:0036316	SREBP-SCAP complex retention in endoplasmic reticulum	biological_process	Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.
GO:0036317	tyrosyl-RNA phosphodiesterase activity	molecular_function	Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.
GO:0036318	peptide pheromone receptor activity	molecular_function	Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.
GO:0036319	mating-type M-factor pheromone receptor activity	molecular_function	Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus.
GO:0036320	mating-type P-factor pheromone receptor activity	molecular_function	Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.
GO:0036321	ghrelin secretion	biological_process	The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone.
GO:0036322	pancreatic polypeptide secretion	biological_process	The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.
GO:0036323	vascular endothelial growth factor receptor-1 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-1 (VEGFR-1) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0036325	vascular endothelial growth factor receptor-3 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-3 (VEGFR-3) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0036331	avascular cornea development in camera-type eye	biological_process	The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.
GO:0036332	placental growth factor receptor activity	molecular_function	Combining with placental growth factor (PlGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0036333	hepatocyte homeostasis	biological_process	Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.
GO:0036334	epidermal stem cell homeostasis	biological_process	Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.
GO:0036335	intestinal stem cell homeostasis	biological_process	Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.
GO:0036336	dendritic cell migration	biological_process	The movement of a dendritic cell within or between different tissues and organs of the body.
GO:0036337	Fas signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
GO:0036338	viral membrane	cellular_component	The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.
GO:0036339	lymphocyte adhesion to endothelial cell of high endothelial venule	biological_process	The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.
GO:0036340	chitin-based cuticle sclerotization by biomineralization	biological_process	The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate.
GO:0036341	chitin-based cuticle sclerotization by protein cross-linking	biological_process	The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.
GO:0036342	post-anal tail morphogenesis	biological_process	The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.
GO:0036343	psychomotor behavior	biological_process	The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.
GO:0036344	platelet morphogenesis	biological_process	Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
GO:0036345	platelet maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
GO:0036346	cellular response to L-cysteine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.
GO:0036348	hydantoin racemase activity	molecular_function	Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.
GO:0036349	galactose-specific flocculation	biological_process	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.
GO:0036350	mannose-specific flocculation	biological_process	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.
GO:0036351	histone H2A-K13 ubiquitination	biological_process	The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin.
GO:0036352	histone H2A-K15 ubiquitination	biological_process	The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin.
GO:0036353	histone H2A-K119 monoubiquitination	biological_process	The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms.
GO:0036354	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.
GO:0036355	2-iminoacetate synthase activity	molecular_function	Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.
GO:0036356	cyclic 2,3-diphosphoglycerate synthetase activity	molecular_function	Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate.
GO:0036357	2-phosphoglycerate kinase activity	molecular_function	Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP.
GO:0036358	lipoteichoic acid D-alanylation	biological_process	The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).
GO:0036359	renal potassium excretion	biological_process	The elimination of potassium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
GO:0036360	sorocarp stalk morphogenesis	biological_process	The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.
GO:0036361	racemase activity, acting on amino acids and derivatives	molecular_function	Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.
GO:0036362	ascus membrane	cellular_component	A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.
GO:0036363	transforming growth factor beta activation	biological_process	The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.
GO:0036364	transforming growth factor beta1 activation	biological_process	The release of transforming growth factor beta1 (TGF-beta1) from its latent state.
GO:0036365	transforming growth factor beta2 activation	biological_process	The release of transforming growth factor beta 2 (TGF-beta2) from its latent state.
GO:0036366	transforming growth factor beta3 activation	biological_process	The release of transforming growth factor beta 3 (TGF-beta3) from its latent state.
GO:0036367	light adaption	biological_process	The ability of a photoreceptor to adjust to varying levels of light.
GO:0036368	cone photoresponse recovery	biological_process	The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.
GO:0036370	D-alanyl carrier activity	molecular_function	Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG).
GO:0036371	protein localization to T-tubule	biological_process	A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
GO:0036372	opsin transport	biological_process	The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0036373	L-fucose mutarotase activity	molecular_function	Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.
GO:0036374	glutathione hydrolase activity	molecular_function	Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.
GO:0036375	Kibra-Ex-Mer complex	cellular_component	An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.
GO:0036376	sodium ion export across plasma membrane	biological_process	The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0036377	arbuscular mycorrhizal association	biological_process	A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.
GO:0036378	calcitriol biosynthetic process from calciol	biological_process	Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
GO:0036379	myofilament	cellular_component	Any of the smallest contractile units of a myofibril (striated muscle fiber).
GO:0036380	UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.
GO:0036381	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.
GO:0036382	flavin reductase (NADH) activity	molecular_function	Catalysis of the reaction: a reduced flavin + NAD+ = an oxidized flavin + 2 H+ + NADH.
GO:0036383	3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.
GO:0036384	CDP phosphatase activity	molecular_function	Catalysis of the reaction: CDP + H2O = CMP + phosphate.
GO:0036386	bacterial nucleoid packaging	biological_process	A process in which chromosomal DNA and associated proteins organize into a compact, orderly bacterial nucleoid. Often resulting in DNA supercoiling.
GO:0036387	pre-replicative complex	cellular_component	A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
GO:0036388	pre-replicative complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
GO:0036389	bacterial pre-replicative complex	cellular_component	A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
GO:0036390	pre-replicative complex assembly involved in bacterial-type DNA replication	biological_process	The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
GO:0036391	medial cortex septin ring	cellular_component	A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.
GO:0036392	chemokine (C-C motif) ligand 20 production	biological_process	The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0036393	thiocyanate peroxidase activity	molecular_function	Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate.
GO:0036394	amylase secretion	biological_process	The controlled release of amylase from a cell.
GO:0036395	pancreatic amylase secretion	biological_process	The controlled release of amylase from a cell of the pancreas.
GO:0036396	RNA N6-methyladenosine methyltransferase complex	cellular_component	A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
GO:0036397	formate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: formate + a quinone = CO2 + a quinol.
GO:0036398	TCR signalosome	cellular_component	A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.
GO:0036399	TCR signalosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.
GO:0036400	short neuropeptide F receptor activity	molecular_function	Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide.
GO:0036401	pyrokinin receptor activity	molecular_function	Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.
GO:0036402	proteasome-activating activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
GO:0036403	arachidonate 8(S)-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
GO:0036407	mycolate outer membrane	cellular_component	A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria).
GO:0036408	histone H3K14 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).
GO:0036409	histone H3-K14 acetyltransferase complex	cellular_component	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.
GO:0036410	Mst2 histone acetyltransferase complex	cellular_component	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.
GO:0036411	H-NS-Cnu complex	cellular_component	A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.
GO:0036412	acetyl-CoA:oxalate CoA-transferase	molecular_function	Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.
GO:0036415	regulation of tRNA stability	biological_process	Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.
GO:0036416	tRNA stabilization	biological_process	Prevention of degradation of tRNA molecules.
GO:0036417	tRNA destabilization	biological_process	Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.
GO:0036420	extrinsic component of mycolate outer membrane	cellular_component	The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0036421	extrinsic component of external side of mycolate outer membrane	cellular_component	The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
GO:0036423	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity	molecular_function	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.
GO:0036424	L-phosphoserine phosphatase activity	molecular_function	Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid.
GO:0036426	ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity	molecular_function	Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.
GO:0036427	all-trans-undecaprenyl-phosphate mannosyltransferase activity	molecular_function	Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.
GO:0036428	adenosylcobinamide kinase (GTP-specific) activity	molecular_function	Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+.
GO:0036429	adenosylcobinamide kinase (ATP-specific) activity	molecular_function	Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+.
GO:0036430	CMP kinase activity	molecular_function	Catalysis of the reaction: ATP + CMP = ADP + CDP.
GO:0036431	dCMP kinase activity	molecular_function	Catalysis of the reaction: ATP + dCMP = ADP + dCDP.
GO:0036432	all-trans undecaprenol kinase activity	molecular_function	Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.
GO:0036433	di-trans, poly-cis-undecaprenol kinase activity	molecular_function	Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.
GO:0036434	nitronate monooxygenase (FMN-linked) activity	molecular_function	Catalysis of the reaction: ethylnitronate + FMNH(2) + O2 = acetaldehyde + FMN + H2O + H+ + nitrite.
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.
GO:0036436	Isw1a complex	cellular_component	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.
GO:0036437	Isw1b complex	cellular_component	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.
GO:0036438	maintenance of lens transparency	biological_process	A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina.
GO:0036440	citrate synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
GO:0036441	2-dehydropantolactone reductase activity	molecular_function	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
GO:0036443	dermatan 6-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.
GO:0036444	calcium import into the mitochondrion	biological_process	A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix.
GO:0036445	neuronal stem cell division	biological_process	The self-renewing division of a neuronal stem cell.
GO:0036446	myofibroblast differentiation	biological_process	The process in which an undifferentiated cell acquires the features of a myofibroblast cell.
GO:0036447	cellular response to sugar-phosphate stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.
GO:0036448	cellular response to glucose-phosphate stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.
GO:0036449	microtubule minus-end	cellular_component	The end of a microtubule that does not preferentially grow (polymerize).
GO:0036450	polyuridylation-dependent decapping of nuclear-transcribed mRNA	biological_process	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.
GO:0036451	cap mRNA methylation	biological_process	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA.
GO:0036452	ESCRT complex	cellular_component	An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.
GO:0036453	transitive RNA interference	biological_process	An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.
GO:0036454	growth factor complex	cellular_component	A protein complex that has growth factor activity.
GO:0036455	iron-sulfur transferase activity	molecular_function	Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).
GO:0036456	L-methionine-(S)-S-oxide reductase activity	molecular_function	Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O.
GO:0036457	keratohyalin granule	cellular_component	A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.
GO:0036458	hepatocyte growth factor binding	molecular_function	Binding to a hepatocyte growth factor.
GO:0036460	cellular response to cell envelope stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.
GO:0036461	BLOC-2 complex binding	molecular_function	Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
GO:0036462	TRAIL-activated apoptotic signaling pathway	biological_process	An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.
GO:0036463	TRAIL receptor activity	molecular_function	Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.
GO:0036464	cytoplasmic ribonucleoprotein granule	cellular_component	A ribonucleoprotein granule located in the cytoplasm.
GO:0036465	synaptic vesicle recycling	biological_process	The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.
GO:0036466	synaptic vesicle recycling via endosome	biological_process	Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate.
GO:0036467	5-hydroxy-L-tryptophan decarboxylase activity	molecular_function	Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.
GO:0036468	L-dopa decarboxylase activity	molecular_function	Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.
GO:0036469	L-tryptophan decarboxylase activity	molecular_function	Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.
GO:0036470	tyrosine 3-monooxygenase activator activity	molecular_function	Binds to and increases the activity of tyrosine 3-monooxygenase (tyrosine hydroxylase).
GO:0036471	cellular response to glyoxal	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.
GO:0036477	somatodendritic compartment	cellular_component	The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.
GO:0036478	L-dopa decarboxylase activator activity	molecular_function	Interacts with and increases L-dopa decarboxylase activity.
GO:0036479	peroxidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of peroxidase.
GO:0036480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).
GO:0036482	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide.
GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GO:0036484	trunk neural crest cell migration	biological_process	The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.
GO:0036485	dorsolateral trunk neural crest cell migration	biological_process	The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells.
GO:0036486	ventral trunk neural crest cell migration	biological_process	The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta.
GO:0036487	nitric-oxide synthase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of nitric oxide synthase.
GO:0036488	CHOP-C/EBP complex	cellular_component	A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.
GO:0036489	neuromelanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers.
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	biological_process	Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
GO:0036491	regulation of translation initiation in response to endoplasmic reticulum stress	biological_process	Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress.
GO:0036492	eiF2alpha phosphorylation in response to endoplasmic reticulum stress	biological_process	The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.
GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress	biological_process	Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress	biological_process	Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.
GO:0036495	negative regulation of translation initiation in response to endoplasmic reticulum stress	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.
GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.
GO:0036497	eIF2alpha dephosphorylation in response to endoplasmic reticulum stress	biological_process	The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.
GO:0036498	IRE1-mediated unfolded protein response	biological_process	The series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB.
GO:0036499	PERK-mediated unfolded protein response	biological_process	The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity.
GO:0036500	ATF6-mediated unfolded protein response	biological_process	The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.
GO:0036501	UFD1-NPL4 complex	cellular_component	A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p.
GO:0036502	Derlin-1-VIMP complex	cellular_component	A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.
GO:0036503	ERAD pathway	biological_process	The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
GO:0036504	Golgi membrane fusion	biological_process	The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.
GO:0036505	prosaposin receptor activity	molecular_function	Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D).
GO:0036506	maintenance of unfolded protein	biological_process	Maintaining a protein in an unfolded, soluble state.
GO:0036507	protein demannosylation	biological_process	The removal of one or more mannose residues from a mannosylated protein.
GO:0036508	protein alpha-1,2-demannosylation	biological_process	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.
GO:0036509	trimming of terminal mannose on B branch	biological_process	The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
GO:0036510	trimming of terminal mannose on C branch	biological_process	The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
GO:0036511	trimming of first mannose on A branch	biological_process	The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
GO:0036512	trimming of second mannose on A branch	biological_process	The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
GO:0036513	Derlin-1 retrotranslocation complex	cellular_component	A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.
GO:0036514	dopaminergic neuron axon guidance	biological_process	The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
GO:0036515	serotonergic neuron axon guidance	biological_process	The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
GO:0036516	chemoattraction of dopaminergic neuron axon	biological_process	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
GO:0036517	chemoattraction of serotonergic neuron axon	biological_process	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
GO:0036518	chemorepulsion of dopaminergic neuron axon	biological_process	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
GO:0036519	chemorepulsion of serotonergic neuron axon	biological_process	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
GO:0036520	astrocyte-dopaminergic neuron signaling	biological_process	Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.
GO:0036521	modulation by symbiont of host protein localization to phagocytic vesicle	biological_process	Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0036522	negative regulation by symbiont of host protein localization to phagocytic vesicle	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0036524	protein deglycase activity	molecular_function	Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.
GO:0036525	protein deglycation	biological_process	The removal of a sugar or dicarbonyl from a glycated protein.
GO:0036526	peptidyl-cysteine deglycation	biological_process	The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.
GO:0036527	peptidyl-arginine deglycation	biological_process	The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein.
GO:0036528	peptidyl-lysine deglycation	biological_process	The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.
GO:0036529	protein deglycation, glyoxal removal	biological_process	The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.
GO:0036530	protein deglycation, methylglyoxal removal	biological_process	The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.
GO:0036531	glutathione deglycation	biological_process	The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine.
GO:0038001	paracrine signaling	biological_process	The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
GO:0038002	endocrine signaling	biological_process	The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.
GO:0038003	G protein-coupled opioid receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0038004	epidermal growth factor receptor ligand maturation	biological_process	Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.
GO:0038006	netrin receptor activity involved in chemoattraction	molecular_function	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.
GO:0038007	netrin-activated signaling pathway	biological_process	The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
GO:0038008	TRAF-mediated signal transduction	biological_process	The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components.
GO:0038009	regulation of signal transduction by receptor internalization	biological_process	Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.
GO:0038010	positive regulation of signal transduction by receptor internalization	biological_process	Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.
GO:0038011	negative regulation of signal transduction by receptor internalization	biological_process	Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.
GO:0038012	negative regulation of Wnt signaling pathway by Wnt receptor internalization	biological_process	Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction.
GO:0038013	positive regulation of Wnt signaling pathway by Wnt receptor internalization	biological_process	Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway.
GO:0038014	negative regulation of insulin receptor signaling pathway by insulin receptor internalization	biological_process	Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.
GO:0038015	positive regulation of insulin receptor signaling pathway by insulin receptor internalization	biological_process	Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.
GO:0038016	insulin receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.
GO:0038017	Wnt receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell.
GO:0038018	Wnt receptor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
GO:0038019	Wnt receptor recycling	biological_process	The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
GO:0038020	insulin receptor recycling	biological_process	The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
GO:0038021	leptin receptor activity	molecular_function	Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038022	G protein-coupled olfactory receptor activity	molecular_function	Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0038023	signaling receptor activity	molecular_function	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0038024	cargo receptor activity	molecular_function	Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
GO:0038025	reelin receptor activity	molecular_function	Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038026	reelin-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038027	apolipoprotein A-I-mediated signaling pathway	biological_process	The series of molecular signals initiated by apolipoprotein A-I binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038031	non-canonical Wnt signaling pathway via JNK cascade	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.
GO:0038032	termination of G protein-coupled receptor signaling pathway	biological_process	The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.
GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
GO:0038034	signal transduction in absence of ligand	biological_process	The series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.
GO:0038035	G protein-coupled receptor signaling in absence of ligand	biological_process	The series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist.
GO:0038036	sphingosine-1-phosphate receptor activity	molecular_function	Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.
GO:0038037	G protein-coupled receptor dimeric complex	cellular_component	A protein complex that contains two G protein-coupled receptors.
GO:0038038	G protein-coupled receptor homodimeric complex	cellular_component	A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.
GO:0038039	G protein-coupled receptor heterodimeric complex	cellular_component	A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR.
GO:0038041	cross-receptor inhibition within G protein-coupled receptor heterodimer	biological_process	Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.
GO:0038043	interleukin-5-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038045	large latent transforming growth factor-beta complex	cellular_component	A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors.
GO:0038046	G protein-coupled enkephalin receptor activity	molecular_function	Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body.
GO:0038047	morphine receptor activity	molecular_function	Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein.
GO:0038048	dynorphin receptor activity	molecular_function	Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.
GO:0038054	G protein-coupled estrogen receptor activity	molecular_function	Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0038055	BMP secretion	biological_process	The controlled release of a member of the BMP family of proteins from a cell.
GO:0038056	negative regulation of BMP signaling pathway by negative regulation of BMP secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell.
GO:0038057	TNFSF11 binding	molecular_function	Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.
GO:0038058	TNFSF11 receptor activity	molecular_function	Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.
GO:0038059	IKKalpha-IKKalpha complex	cellular_component	A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.
GO:0038060	nitric oxide-cGMP-mediated signaling pathway	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.
GO:0038061	non-canonical NF-kappaB signal transduction	biological_process	The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-kappaB. Begins with activation of the NF-kappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-kappa B2 protein (p100) leading to p100 processing and release of an active NF-kappaB (p52). The non-canonical NF-kappaB signaling pathway is generally activated by ligands of the TNF receptor superfamily, including lymphotoxin beta (LTB), CD40, OX40, RANK, TWEAK and B cell-activating factor (BAFF).
GO:0038062	protein tyrosine kinase collagen receptor activity	molecular_function	Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	biological_process	The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038064	collagen receptor activity	molecular_function	Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038065	collagen-activated signaling pathway	biological_process	The series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038066	p38MAPK cascade	biological_process	An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
GO:0038083	peptidyl-tyrosine autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.
GO:0038084	vascular endothelial growth factor signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038085	vascular endothelial growth factor binding	molecular_function	Binding to a vascular endothelial growth factor.
GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038087	VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038088	VEGF-activated platelet-derived growth factor receptor-beta signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.
GO:0038090	positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.
GO:0038091	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.
GO:0038092	nodal signaling pathway	biological_process	The series of molecular signals initiated by nodal protein binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038093	Fc receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
GO:0038094	Fc-gamma receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
GO:0038095	Fc-epsilon receptor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	biological_process	An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
GO:0038097	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	biological_process	An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
GO:0038098	sequestering of BMP from receptor via BMP binding	biological_process	Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.
GO:0038099	nodal receptor complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals).
GO:0038100	nodal binding	molecular_function	Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.
GO:0038101	sequestering of nodal from receptor via nodal binding	biological_process	Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.
GO:0038102	activin receptor antagonist activity	molecular_function	Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.
GO:0038104	nodal receptor complex	cellular_component	A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.
GO:0038105	sequestering of TGFbeta from receptor via TGFbeta binding	biological_process	Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.
GO:0038106	choriogonadotropin hormone binding	molecular_function	Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.
GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry	biological_process	The series of molecular signals initiated by a nodal protein binding of to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves.
GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway	biological_process	The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.
GO:0038109	Kit signaling pathway	biological_process	The series of molecular signals initiated by the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.
GO:0038110	interleukin-2-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-2 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038111	interleukin-7-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-7 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038112	interleukin-8-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-8 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038113	interleukin-9-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-9 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038114	interleukin-21-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-21 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038115	chemokine (C-C motif) ligand 19 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038116	chemokine (C-C motif) ligand 21 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038117	C-C motif chemokine 19 receptor activity	molecular_function	Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038118	C-C chemokine receptor CCR7 signaling pathway	biological_process	The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038119	CCL19-activated CCR7 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038120	CCL21-activated CCR7 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038121	C-C motif chemokine 21 receptor activity	molecular_function	Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038122	C-C motif chemokine 5 receptor activity	molecular_function	Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding of a heterodimeric TLR1:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding of a heterodimeric TLR6:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038127	ERBB signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038128	ERBB2 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.
GO:0038129	ERBB3 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.
GO:0038130	ERBB4 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038131	neuregulin receptor activity	molecular_function	Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038132	neuregulin binding	molecular_function	Binding to a neuregulin, a member of the EGF family of growth factors.
GO:0038133	ERBB2-ERBB3 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.
GO:0038134	ERBB2-EGFR signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.
GO:0038135	ERBB2-ERBB4 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.
GO:0038136	ERBB3-ERBB4 signaling pathway	biological_process	The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.
GO:0038137	ERBB4-EGFR signaling pathway	biological_process	The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.
GO:0038138	ERBB4-ERBB4 signaling pathway	biological_process	The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0038139	ERBB4-EGFR complex	cellular_component	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1).
GO:0038140	ERBB4-ERBB3 complex	cellular_component	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.
GO:0038141	ERBB4-ERBB4 complex	cellular_component	A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).
GO:0038142	EGFR:ERBB2 complex	cellular_component	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.
GO:0038143	ERBB3:ERBB2 complex	cellular_component	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.
GO:0038144	ERBB4:ERBB2 complex	cellular_component	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.
GO:0038145	macrophage colony-stimulating factor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038146	chemokine (C-X-C motif) ligand 12 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the chemokine CXCL12 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038147	C-X-C motif chemokine 12 receptor activity	molecular_function	Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038148	chemokine (C-C motif) ligand 2 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038149	C-C motif chemokine 2 receptor activity	molecular_function	Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038150	C-C chemokine receptor CCR2 signaling pathway	biological_process	The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038151	CCL2-activated CCR2 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038152	C-C chemokine receptor CCR4 signaling pathway	biological_process	The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038153	CCL2-activated CCR4 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038154	interleukin-11-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of interleukin-11 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038155	interleukin-23-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-23 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038156	interleukin-3-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-3 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038157	granulocyte-macrophage colony-stimulating factor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.
GO:0038158	granulocyte colony-stimulating factor signaling pathway	biological_process	The series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).
GO:0038159	C-X-C chemokine receptor CXCR4 signaling pathway	biological_process	The series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038160	CXCL12-activated CXCR4 signaling pathway	biological_process	The series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038161	prolactin signaling pathway	biological_process	The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038162	erythropoietin-mediated signaling pathway	biological_process	The series of molecular signals initiated by erythropoietin (EPO) binding to the erythropoietin receptor (EPO-R) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038163	thrombopoietin-mediated signaling pathway	biological_process	The series of molecular signals initiated by thrombopoietin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038164	thrombopoietin receptor activity	molecular_function	Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038165	oncostatin-M-mediated signaling pathway	biological_process	The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
GO:0038166	angiotensin-activated signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038169	somatostatin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0038170	somatostatin signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038171	cannabinoid signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
GO:0038172	interleukin-33-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-33 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038173	interleukin-17A-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-17A binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038174	interleukin-17A receptor activity	molecular_function	Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0038175	negative regulation of SREBP signaling pathway in response to increased oxygen levels	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.
GO:0038176	positive regulation of SREBP signaling pathway in response to decreased oxygen levels	biological_process	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.
GO:0038177	death receptor agonist activity	molecular_function	Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.
GO:0038178	complement component C5a signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
GO:0038179	neurotrophin signaling pathway	biological_process	The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
GO:0038180	nerve growth factor signaling pathway	biological_process	The series of molecular signals initiated by nerve growth factor (NGF) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038181	bile acid receptor activity	molecular_function	Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
GO:0038182	G protein-coupled bile acid receptor activity	molecular_function	Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0038183	bile acid signaling pathway	biological_process	The series of molecular signals initiated by bile acid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038184	cell surface bile acid receptor signaling pathway	biological_process	The series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038185	intracellular bile acid receptor signaling pathway	biological_process	The series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038186	lithocholic acid receptor activity	molecular_function	Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.
GO:0038187	pattern recognition receptor activity	molecular_function	Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.
GO:0038188	cholecystokinin signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by cholecystokinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038189	neuropilin signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038190	VEGF-activated neuropilin signaling pathway	biological_process	The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038191	neuropilin binding	molecular_function	Binding to a member of the neuropilin family.
GO:0038192	gastric inhibitory peptide signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by gastric inhibitory peptide (GIP) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038193	thromboxane A2 signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by thromboxane A2 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038194	thyroid-stimulating hormone signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by thyroid-stimulating hormone (thyrotropin) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038195	urokinase plasminogen activator signaling pathway	biological_process	The series of molecular signals initiated by urokinase plasminogen activator binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0038196	type III interferon-mediated signaling pathway	biological_process	The series of molecular signals initiated by type III interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far.
GO:0038197	type I interferon receptor complex	cellular_component	A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
GO:0038198	auxin receptor activity	molecular_function	Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).
GO:0038199	ethylene receptor activity	molecular_function	Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.
GO:0038200	ethylene receptor histidine kinase activity	molecular_function	Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
GO:0038201	TOR complex	cellular_component	A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.
GO:0038202	TORC1 signaling	biological_process	A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
GO:0038203	TORC2 signaling	biological_process	A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
GO:0039003	pronephric field specification	biological_process	The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.
GO:0039004	specification of pronephric proximal tubule identity	biological_process	The process in which the proximal tubule of the pronephric nephron acquires its identity.
GO:0039005	specification of pronephric tubule identity	biological_process	The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
GO:0039006	pronephric nephron tubule formation	biological_process	The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.
GO:0039007	pronephric nephron morphogenesis	biological_process	The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.
GO:0039008	pronephric nephron tubule morphogenesis	biological_process	The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.
GO:0039009	rectal diverticulum development	biological_process	The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.
GO:0039010	specification of pronephric distal tubule identity	biological_process	The process in which the distal tubule of the pronephric nephron acquires its identity.
GO:0039011	pronephric proximal tubule morphogenesis	biological_process	The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
GO:0039012	pronephric sinus development	biological_process	The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.
GO:0039013	pronephric distal tubule morphogenesis	biological_process	The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
GO:0039014	cell differentiation involved in pronephros development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.
GO:0039015	cell proliferation involved in pronephros development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.
GO:0039016	cell-cell signaling involved in pronephros development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.
GO:0039017	pattern specification involved in pronephros development	biological_process	Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.
GO:0039018	nephrostome development	biological_process	The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.
GO:0039019	pronephric nephron development	biological_process	The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.
GO:0039020	pronephric nephron tubule development	biological_process	The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.
GO:0039021	pronephric glomerulus development	biological_process	The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.
GO:0039022	pronephric duct development	biological_process	The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.
GO:0039023	pronephric duct morphogenesis	biological_process	The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.
GO:0039501	suppression by virus of host type I interferon production	biological_process	Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0039502	suppression by virus of host type I interferon-mediated signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0039503	suppression by virus of host innate immune response	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.
GO:0039504	suppression by virus of host adaptive immune response	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
GO:0039505	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II	biological_process	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex.
GO:0039506	modulation by virus of host molecular function	biological_process	The process in which a virus effects a change in the function of a host protein via a direct interaction.
GO:0039507	suppression by virus of host molecular function	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein.
GO:0039513	suppression by virus of host catalytic activity	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity.
GO:0039514	disruption by virus of host JAK-STAT cascade	biological_process	A process in which a virus interferes with, inhibits or stops the JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0039516	modulation by virus of host catalytic activity	biological_process	The process in which a virus effects a change in host enzyme activity.
GO:0039519	modulation by virus of host autophagy	biological_process	Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.
GO:0039520	induction by virus of host autophagy	biological_process	Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
GO:0039521	suppression by virus of host autophagy	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.
GO:0039522	suppression by virus of host mRNA export from nucleus	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.
GO:0039523	suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity.
GO:0039524	suppression by virus of host mRNA processing	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
GO:0039525	modulation by virus of host chromatin organization	biological_process	Any process in which a virus effects a change in the organization of chromatin in the host.
GO:0039526	modulation by virus of host apoptotic process	biological_process	Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.
GO:0039527	disruption by virus of host TRAF-mediated signal transduction	biological_process	A process in which a virus interferes with, inhibits or stops TRAF-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0039529	RIG-I signaling pathway	biological_process	The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.
GO:0039530	MDA-5 signaling pathway	biological_process	The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines.
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus.
GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway in response to a virus.
GO:0039533	regulation of MDA-5 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
GO:0039534	negative regulation of MDA-5 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway.
GO:0039535	regulation of RIG-I signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the RIG-I signaling pathway.
GO:0039536	negative regulation of RIG-I signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway.
GO:0039537	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the host viral-induced cytoplasmic pattern recognition receptor signaling pathway. This is a mechanism by which the virus evades the host innate immune response.
GO:0039540	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity	biological_process	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
GO:0039545	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity	biological_process	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.
GO:0039548	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity	biological_process	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
GO:0039552	RIG-I binding	molecular_function	Binding to RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA.
GO:0039554	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity	biological_process	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
GO:0039556	MDA-5 binding	molecular_function	Binding to MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA.
GO:0039557	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity	biological_process	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
GO:0039560	disruption by virus of host JAK-STAT cascade via inhibition of host IRF9 activity	biological_process	Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.
GO:0039562	disruption by virus of host JAK-STAT cascade via inhibition of STAT activity	biological_process	Any process in which a virus interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.
GO:0039563	disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1).
GO:0039564	disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).
GO:0039573	suppression by virus of host complement activation	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase.
GO:0039574	disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity	biological_process	Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.
GO:0039576	disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity	biological_process	Any process in which interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1).
GO:0039579	suppression by virus of host ISG15-protein conjugation	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 conjugation to a susbtrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives.
GO:0039580	suppression by virus of host PKR signaling	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha, inhibiting protein synthesis as an antiviral response.
GO:0039585	PKR-mediated signaling	biological_process	A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK2), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation.
GO:0039587	suppression by virus of host tetherin activity	biological_process	Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.
GO:0039588	suppression by virus of host antigen processing and presentation	biological_process	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex.
GO:0039592	perturbation by virus of G2/M transition of host mitotic cell cycle	biological_process	A process in which a virus interferes with the progression of the host mitotic cell cycle from G2 phase to M phase, leading to arrest in G2 phase.
GO:0039593	peturbation by virus of host exit from mitosis	biological_process	A process in which a virus interferes with the host cell completing the M phase of the cell cycle.
GO:0039594	endoribonuclease activity involved in viral induction of host mRNA catabolic process	molecular_function	Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA.
GO:0039595	induction by virus of catabolism of host mRNA	biological_process	The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).
GO:0039602	suppression by virus of host transcription initiation from RNA polymerase II promoter	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.
GO:0039604	suppression by virus of host translation	biological_process	Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA, for example by cleavage of the host mRNAs.
GO:0039606	suppression by virus of host translation initiation	biological_process	Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.
GO:0039615	T=1 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.
GO:0039616	T=2 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.
GO:0039617	T=3 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
GO:0039618	T=pseudo3 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
GO:0039619	T=4 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.
GO:0039620	T=7 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.
GO:0039621	T=13 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres.
GO:0039622	T=16 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.
GO:0039623	T=25 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.
GO:0039624	viral outer capsid	cellular_component	The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.
GO:0039625	viral inner capsid	cellular_component	The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.
GO:0039626	viral intermediate capsid	cellular_component	The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions.
GO:0039627	T=147 icosahedral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins.
GO:0039628	T=169 icosahedral viral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins.
GO:0039629	T=219 icosahedral capsid	cellular_component	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins.
GO:0039630	RNA translocase activity	molecular_function	Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis.
GO:0039634	killing by virus of host cell during superinfection exclusion	biological_process	The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus.
GO:0039635	suppression by virus of host peptidoglycan biosynthetic process	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
GO:0039636	suppression by virus of host cell wall biogenesis	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.
GO:0039637	catabolism by virus of host DNA	biological_process	The breakdown of host DNA, deoxyribonucleic acid, by a virus.
GO:0039638	lipopolysaccharide-mediated virion attachment to host cell	biological_process	The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface.
GO:0039639	suppression by virus of host cell lysis in response to superinfection	biological_process	The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.
GO:0039640	viral release via suppression of host peptidoglycan biosynthetic process	biological_process	The dissemination of mature viral particles from a host cell, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
GO:0039641	viral inner membrane	cellular_component	The lipid bilayer of a virion contained inside the protein capsid.
GO:0039642	virion nucleoid	cellular_component	The region of a virion in which the nucleic acid is confined.
GO:0039643	host cell viral nucleoid	cellular_component	The region of a host cell that contains the viral genome.
GO:0039644	suppression by virus of host NF-kappaB cascade	biological_process	Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade.
GO:0039645	perturbation by virus of host G1/S transition checkpoint	biological_process	A process in which a virus interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0039646	perturbation by virus of host G0/G1 transition checkpoint	biological_process	A process in which a virus interferes with the normal execution of the host cell G0/G1 transition checkpoint.
GO:0039648	modulation by symbiont of host protein ubiquitination	biological_process	Any process by which a symbiont increases or decreases ubiquitination of target proteins of a host organism.
GO:0039652	induction by virus of host NF-kappaB cascade	biological_process	A process in which a virus initiates, promotes, or enhances a host NF-kappaB signaling cascade.
GO:0039653	suppression by virus of host transcription	biological_process	Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.
GO:0039654	fusion of virus membrane with host endosome membrane	biological_process	Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.
GO:0039656	modulation by virus of host gene expression	biological_process	The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
GO:0039657	suppression by virus of host gene expression	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
GO:0039658	TBK1-IKKE-DDX3 complex	cellular_component	A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3.
GO:0039660	structural constituent of virion	molecular_function	The action of a molecule that contributes to the structural integrity of a virion.
GO:0039661	host organelle outer membrane	cellular_component	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.
GO:0039662	host cell outer membrane	cellular_component	A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell.
GO:0039663	membrane fusion involved in viral entry into host cell	biological_process	Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.
GO:0039664	lysis of host organelle involved in viral entry into host cell	biological_process	The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm.
GO:0039665	permeabilization of host organelle membrane involved in viral entry into host cell	biological_process	Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.
GO:0039666	virion attachment to host cell pilus	biological_process	The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.
GO:0039667	viral entry into host cell via pilus retraction	biological_process	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus.
GO:0039668	viral entry into host cell via pilus basal pore	biological_process	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way.
GO:0039669	viral entry into host cell via pilus retraction and membrane fusion	biological_process	The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane.
GO:0039670	viral capsid, turret	cellular_component	A turret-like appendage formed at the vertices of an icosahedral capsid.
GO:0039671	evasion by virus of host natural killer cell activity	biological_process	Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.
GO:0039672	suppression by virus of host natural killer cell activation	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.
GO:0039673	evasion by virus of host dendritic cell activity	biological_process	Any process by which a virus avoids the effects mediated by the host organism's dendritic cells.
GO:0039674	exit of virus from host cell nucleus	biological_process	The directed movement of the viral genome or a viral particle out of the host cell nucleus.
GO:0039675	exit of virus from host cell nucleus through nuclear pore	biological_process	The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.
GO:0039677	exit of virus from host cell nucleus via nuclear envelope disassembly	biological_process	The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.
GO:0039678	viral genome ejection through host cell envelope	biological_process	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.
GO:0039679	viral occlusion body	cellular_component	A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.
GO:0039680	actin-dependent intracellular transport of virus towards nucleus	biological_process	The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.
GO:0039682	rolling circle viral DNA replication	biological_process	A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.
GO:0039683	rolling circle double-stranded viral DNA replication	biological_process	A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.
GO:0039684	rolling circle single-stranded viral DNA replication	biological_process	A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.
GO:0039685	rolling hairpin viral DNA replication	biological_process	A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.
GO:0039686	bidirectional double-stranded viral DNA replication	biological_process	A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.
GO:0039687	viral DNA strand displacement replication	biological_process	A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).
GO:0039688	viral double stranded DNA replication via reverse transcription	biological_process	A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.
GO:0039689	negative stranded viral RNA replication	biological_process	A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).
GO:0039690	positive stranded viral RNA replication	biological_process	A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.
GO:0039691	double stranded viral RNA replication	biological_process	A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	biological_process	A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.
GO:0039693	viral DNA genome replication	biological_process	The replication of a viral DNA genome.
GO:0039694	viral RNA genome replication	biological_process	The replication of a viral RNA genome.
GO:0039695	DNA-templated viral transcription	biological_process	A transcription process that uses a viral DNA as a template.
GO:0039696	RNA-templated viral transcription	biological_process	A transcription process that uses viral RNA as a template.
GO:0039697	negative stranded viral RNA transcription	biological_process	A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.
GO:0039698	polyadenylation of viral mRNA by polymerase stuttering	biological_process	Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.
GO:0039699	viral mRNA cap methylation	biological_process	An innate immune response evasion mechanism in which a virus methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.
GO:0039700	fusion of viral membrane with host outer nuclear membrane	biological_process	Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.
GO:0039701	microtubule-dependent intracellular transport of viral material towards cell periphery	biological_process	The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.
GO:0039702	viral budding via host ESCRT complex	biological_process	Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.
GO:0039703	RNA replication	biological_process	The cellular metabolic process in which a cell duplicates one or more molecules of RNA.
GO:0039704	viral translational shunt	biological_process	A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.
GO:0039705	viral translational readthrough	biological_process	The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.
GO:0039706	co-receptor binding	molecular_function	Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.
GO:0039707	pore formation by virus in membrane of host cell	biological_process	The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.
GO:0039708	nuclear capsid assembly	biological_process	The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.
GO:0039709	cytoplasmic capsid assembly	biological_process	The assembly of a virus capsid that occurs in the cytoplasm.
GO:0039710	cytoplasmic icosahedral capsid assembly	biological_process	The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.
GO:0039711	cytoplasmic helical capsid assembly	biological_process	The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.
GO:0039713	viral factory	cellular_component	An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.
GO:0039714	cytoplasmic viral factory	cellular_component	A viral factory located in the cytoplasm of a host cell.
GO:0039715	nuclear viral factory	cellular_component	A viral factory located in the nucleus of a host cell.
GO:0039716	viroplasm viral factory	cellular_component	A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.
GO:0039717	spherule viral factory	cellular_component	A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus.
GO:0039718	double membrane vesicle viral factory	cellular_component	A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae.
GO:0039719	tube viral factory	cellular_component	A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.
GO:0039720	virogenic stroma	cellular_component	A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.
GO:0039721	peristromal region viral factory	cellular_component	A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.
GO:0039722	suppression by virus of host toll-like receptor signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism.
GO:0039723	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity	biological_process	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.
GO:0039724	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity	biological_process	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).
GO:0040001	establishment of mitotic spindle localization	biological_process	The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
GO:0040002	collagen and cuticulin-based cuticle development	biological_process	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.
GO:0040003	chitin-based cuticle development	biological_process	Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
GO:0040004	collagen and cuticulin-based cuticle attachment to epithelium	biological_process	Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.
GO:0040005	chitin-based cuticle attachment to epithelium	biological_process	Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.
GO:0040007	growth	biological_process	The increase in size or mass of an entire organism, a part of an organism or a cell.
GO:0040008	regulation of growth	biological_process	Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
GO:0040009	regulation of growth rate	biological_process	Any process that modulates the rate of growth of all or part of an organism.
GO:0040010	positive regulation of growth rate	biological_process	Any process that increases the rate of growth of all or part of an organism.
GO:0040011	locomotion	biological_process	Self-propelled movement of a cell or organism from one location to another.
GO:0040012	regulation of locomotion	biological_process	Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
GO:0040013	negative regulation of locomotion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
GO:0040014	regulation of multicellular organism growth	biological_process	Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
GO:0040015	negative regulation of multicellular organism growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
GO:0040016	embryonic cleavage	biological_process	The first few specialized divisions of an activated animal egg.
GO:0040017	positive regulation of locomotion	biological_process	Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
GO:0040018	positive regulation of multicellular organism growth	biological_process	Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
GO:0040019	positive regulation of embryonic development	biological_process	Any process that activates or increases the frequency, rate or extent of embryonic development.
GO:0040020	regulation of meiotic nuclear division	biological_process	Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
GO:0040021	hermaphrodite germ-line sex determination	biological_process	The determination of sex and sexual phenotype in the germ line of a hermaphrodite.
GO:0040022	feminization of hermaphroditic germ-line	biological_process	The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.
GO:0040024	dauer larval development	biological_process	The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
GO:0040025	vulval development	biological_process	The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
GO:0040026	positive regulation of vulval development	biological_process	Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
GO:0040027	negative regulation of vulval development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
GO:0040028	regulation of vulval development	biological_process	Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
GO:0040029	epigenetic regulation of gene expression	biological_process	A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal.
GO:0040031	snRNA modification	biological_process	The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.
GO:0040032	post-embryonic body morphogenesis	biological_process	The process in which the anatomical structures of the post-embryonic soma are generated and organized.
GO:0040033	sRNA-mediated post-transcriptional gene silencing	biological_process	A post-transcriptional gene silencing pathway mediated by the action of small regulatory non-coding RNAs (sRNAs). sRNAs are 20-500 nucleotides in length and found in bacteria.
GO:0040034	regulation of development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
GO:0040038	polar body extrusion after meiotic divisions	biological_process	The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.
GO:0040039	inductive cell migration	biological_process	Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.
GO:0040040	thermosensory behavior	biological_process	Behavior that is dependent upon the sensation of temperature.
GO:0042000	translocation of peptides or proteins into host	biological_process	The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042001	hermaphrodite somatic sex determination	biological_process	The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.
GO:0042003	masculinization of hermaphrodite soma	biological_process	Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.
GO:0042004	feminization of hermaphrodite soma	biological_process	Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.
GO:0042006	masculinization of hermaphroditic germ-line	biological_process	The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.
GO:0042007	interleukin-18 binding	molecular_function	Binding to interleukin-18.
GO:0042008	interleukin-18 receptor activity	molecular_function	Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042009	interleukin-15 binding	molecular_function	Binding to interleukin-15.
GO:0042010	interleukin-15 receptor activity	molecular_function	Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042011	interleukin-16 binding	molecular_function	Binding to interleukin-16.
GO:0042012	interleukin-16 receptor activity	molecular_function	Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042013	interleukin-19 binding	molecular_function	Binding to interleukin-19.
GO:0042014	interleukin-19 receptor activity	molecular_function	Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042015	interleukin-20 binding	molecular_function	Binding to interleukin-20.
GO:0042016	interleukin-20 receptor activity	molecular_function	Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042017	interleukin-22 binding	molecular_function	Binding to interleukin-22.
GO:0042018	interleukin-22 receptor activity	molecular_function	Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042019	interleukin-23 binding	molecular_function	Binding to interleukin-23.
GO:0042020	interleukin-23 receptor activity	molecular_function	Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0042021	granulocyte macrophage colony-stimulating factor complex binding	molecular_function	Binding to a granulocyte macrophage colony-stimulating factor complex.
GO:0042022	interleukin-12 receptor complex	cellular_component	A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
GO:0042023	DNA endoreduplication	biological_process	Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
GO:0042025	host cell nucleus	cellular_component	A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042026	protein refolding	biological_process	The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
GO:0042030	ATPase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces an ATP hydrolysis activity.
GO:0042037	peptidyl-histidine methylation, to form pros-methylhistidine	biological_process	The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).
GO:0042038	peptidyl-histidine methylation, to form tele-methylhistidine	biological_process	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine).
GO:0042039	vanadium incorporation into metallo-sulfur cluster	biological_process	The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n).
GO:0042040	metal incorporation into metallo-molybdopterin complex	biological_process	The incorporation of a metal into a metallo-molybdopterin complex.
GO:0042042	tungsten incorporation into tungsten-molybdopterin complex	biological_process	The incorporation of tungsten into a tungsten-molybdopterin complex.
GO:0042043	neurexin family protein binding	molecular_function	Binding to a neurexin, a synaptic cell surface protein related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
GO:0042044	fluid transport	biological_process	The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042045	epithelial fluid transport	biological_process	The directed movement of fluid across epithelia.
GO:0042046	W-molybdopterin cofactor metabolic process	biological_process	The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
GO:0042047	W-molybdopterin cofactor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
GO:0042048	olfactory behavior	biological_process	The behavior of an organism in response to an odor.
GO:0042049	intracellular acyl-CoA homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of acyl-CoA within a cell.
GO:0042051	compound eye photoreceptor development	biological_process	The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
GO:0042052	rhabdomere development	biological_process	The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
GO:0042053	regulation of dopamine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
GO:0042054	histone methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0042056	chemoattractant activity	molecular_function	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
GO:0042060	wound healing	biological_process	The series of events that restore integrity to a damaged tissue, following an injury.
GO:0042062	long-term strengthening of neuromuscular junction	biological_process	Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.
GO:0042063	gliogenesis	biological_process	The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.
GO:0042065	glial cell growth	biological_process	Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
GO:0042066	perineurial glial growth	biological_process	Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.
GO:0042067	establishment of ommatidial planar polarity	biological_process	The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
GO:0042068	regulation of pteridine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
GO:0042069	regulation of catecholamine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.
GO:0042070	maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification	biological_process	Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster.
GO:0042071	leucokinin receptor activity	molecular_function	Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.
GO:0042073	intraciliary transport	biological_process	The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
GO:0042074	cell migration involved in gastrulation	biological_process	The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
GO:0042075	nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	biological_process	The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
GO:0042076	protein phosphate-linked glycosylation	biological_process	The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.
GO:0042077	protein phosphate-linked glycosylation via serine	biological_process	The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.
GO:0042078	germ-line stem cell division	biological_process	The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
GO:0042081	GSI anchor metabolic process	biological_process	The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.
GO:0042082	GSI anchor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.
GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.
GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.
GO:0042086	5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.
GO:0042088	T-helper 1 type immune response	biological_process	An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
GO:0042092	type 2 immune response	biological_process	An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
GO:0042093	T-helper cell differentiation	biological_process	The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
GO:0042098	T cell proliferation	biological_process	The expansion of a T cell population by cell division. Follows T cell activation.
GO:0042100	B cell proliferation	biological_process	The expansion of a B cell population by cell division. Follows B cell activation.
GO:0042101	T cell receptor complex	cellular_component	A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
GO:0042102	positive regulation of T cell proliferation	biological_process	Any process that activates or increases the rate or extent of T cell proliferation.
GO:0042103	positive regulation of T cell homeostatic proliferation	biological_process	Any process that activates or increases the rate or extent of resting T cell proliferation.
GO:0042104	positive regulation of activated T cell proliferation	biological_process	Any process that activates or increases the rate or extent of activated T cell proliferation.
GO:0042105	alpha-beta T cell receptor complex	cellular_component	A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.
GO:0042106	gamma-delta T cell receptor complex	cellular_component	A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein.
GO:0042110	T cell activation	biological_process	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0042113	B cell activation	biological_process	The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0042116	macrophage activation	biological_process	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0042117	monocyte activation	biological_process	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0042118	endothelial cell activation	biological_process	The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0042119	neutrophil activation	biological_process	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0042120	alginic acid metabolic process	biological_process	The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
GO:0042121	alginic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
GO:0042122	alginic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
GO:0042123	glucanosyltransferase activity	molecular_function	Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.
GO:0042124	1,3-beta-glucanosyltransferase activity	molecular_function	Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.
GO:0042125	protein galactosylation	biological_process	The addition of a galactose molecule to a protein amino acid.
GO:0042126	nitrate metabolic process	biological_process	The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.
GO:0042127	regulation of cell population proliferation	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation.
GO:0042128	nitrate assimilation	biological_process	The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
GO:0042129	regulation of T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of T cell proliferation.
GO:0042130	negative regulation of T cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
GO:0042131	thiamine phosphate phosphatase activity	molecular_function	Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.
GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
GO:0042133	neurotransmitter metabolic process	biological_process	The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
GO:0042134	rRNA primary transcript binding	molecular_function	Binding to an unprocessed ribosomal RNA transcript.
GO:0042135	neurotransmitter catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
GO:0042136	neurotransmitter biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
GO:0042137	sequestering of neurotransmitter	biological_process	The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system.
GO:0042138	meiotic DNA double-strand break formation	biological_process	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.
GO:0042139	early meiotic recombination nodule assembly	biological_process	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene.
GO:0042140	late meiotic recombination nodule assembly	biological_process	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over.
GO:0042144	vacuole fusion, non-autophagic	biological_process	The fusion of two vacuole membranes to form a single vacuole.
GO:0042147	retrograde transport, endosome to Golgi	biological_process	The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
GO:0042148	strand invasion	biological_process	The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
GO:0042149	cellular response to glucose starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
GO:0042150	plasmid recombination	biological_process	A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.
GO:0042151	nematocyst	cellular_component	An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.
GO:0042152	RNA-mediated DNA recombination	biological_process	The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele.
GO:0042157	lipoprotein metabolic process	biological_process	The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
GO:0042158	lipoprotein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
GO:0042159	lipoprotein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
GO:0042160	lipoprotein modification	biological_process	The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0042161	lipoprotein oxidation	biological_process	The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group.
GO:0042162	telomeric DNA binding	molecular_function	Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
GO:0042163	interleukin-12 beta subunit binding	molecular_function	Binding to the beta subunit of interleukin-12.
GO:0042164	interleukin-12 alpha subunit binding	molecular_function	Binding to the alpha subunit of interleukin-12.
GO:0042165	neurotransmitter binding	molecular_function	Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
GO:0042166	acetylcholine binding	molecular_function	Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
GO:0042167	heme catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0042168	heme metabolic process	biological_process	The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0042169	SH2 domain binding	molecular_function	Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.
GO:0042170	plastid membrane	cellular_component	Either of the lipid bilayers that surround a plastid and form the plastid envelope.
GO:0042171	lysophosphatidic acid acyltransferase activity	molecular_function	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.
GO:0042173	regulation of sporulation resulting in formation of a cellular spore	biological_process	Any process that modulates the frequency, rate or extent of spore formation.
GO:0042174	negative regulation of sporulation resulting in formation of a cellular spore	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network	cellular_component	The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.
GO:0042176	regulation of protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0042177	negative regulation of protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process.
GO:0042178	xenobiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0042179	nicotine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
GO:0042180	cellular ketone metabolic process	biological_process	The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GO:0042181	ketone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GO:0042182	ketone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GO:0042183	formate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
GO:0042184	xylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.
GO:0042185	m-xylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.
GO:0042186	o-xylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
GO:0042187	p-xylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.
GO:0042188	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
GO:0042189	vanillin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.
GO:0042190	vanillin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.
GO:0042191	methylmercury metabolic process	biological_process	The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species.
GO:0042192	methylmercury biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.
GO:0042193	methylmercury catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal.
GO:0042194	quinate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid.
GO:0042195	aerobic gallate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.
GO:0042196	chlorinated hydrocarbon metabolic process	biological_process	The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.
GO:0042197	halogenated hydrocarbon metabolic process	biological_process	The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine.
GO:0042198	nylon metabolic process	biological_process	The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.
GO:0042199	cyanuric acid metabolic process	biological_process	The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives.
GO:0042200	cyanuric acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.
GO:0042201	N-cyclopropylmelamine metabolic process	biological_process	The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.
GO:0042202	N-cyclopropylmelamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.
GO:0042203	toluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.
GO:0042204	s-triazine compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.
GO:0042205	chlorinated hydrocarbon catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.
GO:0042206	halogenated hydrocarbon catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.
GO:0042207	styrene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.
GO:0042208	propylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.
GO:0042209	orcinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.
GO:0042210	octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter.
GO:0042211	dimethylsilanediol catabolic process	biological_process	The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.
GO:0042212	cresol metabolic process	biological_process	The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.
GO:0042213	m-cresol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.
GO:0042214	terpene metabolic process	biological_process	The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.
GO:0042215	anaerobic phenol-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
GO:0042216	phenanthrene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.
GO:0042217	1-aminocyclopropane-1-carboxylate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
GO:0042219	cellular modified amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0042220	response to cocaine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
GO:0042221	response to chemical	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0042242	cobyrinic acid a,c-diamide synthase activity	molecular_function	Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.
GO:0042243	asexual spore wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.
GO:0042244	spore wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.
GO:0042245	RNA repair	biological_process	Any process that results in the repair of damaged RNA.
GO:0042246	tissue regeneration	biological_process	The regrowth of lost or destroyed tissues.
GO:0042247	establishment of planar polarity of follicular epithelium	biological_process	Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.
GO:0042248	maintenance of polarity of follicular epithelium	biological_process	The maintenance of an established polarized follicular epithelial sheet.
GO:0042249	establishment of planar polarity of embryonic epithelium	biological_process	Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.
GO:0042250	maintenance of polarity of embryonic epithelium	biological_process	The maintenance of an established polarized embryonic epithelial sheet.
GO:0042251	maintenance of polarity of larval imaginal disc epithelium	biological_process	The maintenance of an established polarized larval imaginal disc epithelium.
GO:0042252	establishment of planar polarity of larval imaginal disc epithelium	biological_process	Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.
GO:0042254	ribosome biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
GO:0042255	ribosome assembly	biological_process	The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
GO:0042256	cytosolic ribosome assembly	biological_process	The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol.
GO:0042258	molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide	biological_process	The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.
GO:0042262	DNA protection	biological_process	Any process in which DNA is protected from damage by, for example, oxidative stress.
GO:0042263	neuropeptide F receptor activity	molecular_function	Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.
GO:0042264	peptidyl-aspartic acid hydroxylation	biological_process	The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.
GO:0042267	natural killer cell mediated cytotoxicity	biological_process	The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
GO:0042268	regulation of cytolysis	biological_process	Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.
GO:0042269	regulation of natural killer cell mediated cytotoxicity	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.
GO:0042270	protection from natural killer cell mediated cytotoxicity	biological_process	The process of protecting a cell from natural killer cell mediated cytotoxicity.
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	biological_process	The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
GO:0042272	nuclear RNA export factor complex	cellular_component	A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.
GO:0042273	ribosomal large subunit biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
GO:0042274	ribosomal small subunit biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
GO:0042275	error-free postreplication DNA repair	biological_process	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.
GO:0042276	error-prone translesion synthesis	biological_process	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.
GO:0042277	peptide binding	molecular_function	Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.
GO:0042278	purine nucleoside metabolic process	biological_process	The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0042279	nitrite reductase (cytochrome, ammonia-forming) activity	molecular_function	Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+.
GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	molecular_function	Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
GO:0042283	dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	molecular_function	Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
GO:0042284	sphingolipid delta-4 desaturase activity	molecular_function	Catalysis of the reaction: a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ -> a sphingosine ceramide (aka (4E)-sphing-4-enine ceramide) + 2 ferricytochrome b5 + 2 H2O.
GO:0042285	xylosyltransferase activity	molecular_function	Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0042286	glutamate-1-semialdehyde 2,1-aminomutase activity	molecular_function	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
GO:0042287	MHC protein binding	molecular_function	Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
GO:0042288	MHC class I protein binding	molecular_function	Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
GO:0042289	MHC class II protein binding	molecular_function	Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
GO:0042292	URM1 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0042293	Hub1 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0042294	URM1 transferase activity	molecular_function	Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y = Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages.
GO:0042296	ISG15 transferase activity	molecular_function	Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.
GO:0042297	vocal learning	biological_process	A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
GO:0042299	lupeol synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.
GO:0042300	beta-amyrin synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.
GO:0042301	phosphate ion binding	molecular_function	Binding to a phosphate ion.
GO:0042302	structural constituent of cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of a cuticle.
GO:0042303	molting cycle	biological_process	The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.
GO:0042304	regulation of fatty acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.
GO:0042305	specification of segmental identity, mandibular segment	biological_process	The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0042306	regulation of protein import into nucleus	biological_process	Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.
GO:0042307	positive regulation of protein import into nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
GO:0042308	negative regulation of protein import into nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.
GO:0042309	homoiothermy	biological_process	Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment.
GO:0042310	vasoconstriction	biological_process	A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.
GO:0042311	vasodilation	biological_process	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
GO:0042313	protein kinase C deactivation	biological_process	Any process resulting in the inhibition or termination of the activity of protein kinase C.
GO:0042314	bacteriochlorophyll binding	molecular_function	Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.
GO:0042316	penicillin metabolic process	biological_process	The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus.
GO:0042317	penicillin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0042318	penicillin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	biological_process	Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	biological_process	Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep	biological_process	Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	biological_process	Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.
GO:0042324	orexin receptor binding	molecular_function	Binding to an orexin receptor.
GO:0042325	regulation of phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
GO:0042326	negative regulation of phosphorylation	biological_process	Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
GO:0042327	positive regulation of phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.
GO:0042329	structural constituent of collagen and cuticulin-based cuticle	molecular_function	The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans.
GO:0042330	taxis	biological_process	The directed movement of a motile cell or organism in response to an external stimulus.
GO:0042331	phototaxis	biological_process	The directed movement of a motile cell or organism in response to light.
GO:0042332	gravitaxis	biological_process	The directed movement of a motile cell or organism in response to gravity.
GO:0042333	chemotaxis to oxidizable substrate	biological_process	The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.
GO:0042334	taxis to electron acceptor	biological_process	The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.
GO:0042335	cuticle development	biological_process	The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
GO:0042337	cuticle development involved in chitin-based cuticle molting cycle	biological_process	The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.
GO:0042338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle	biological_process	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.
GO:0042339	keratan sulfate metabolic process	biological_process	The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
GO:0042340	keratan sulfate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
GO:0042341	cyanogenic glycoside metabolic process	biological_process	The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
GO:0042342	cyanogenic glycoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
GO:0042343	indole glucosinolate metabolic process	biological_process	The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.
GO:0042344	indole glucosinolate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
GO:0042349	guiding stereospecific synthesis activity	molecular_function	The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.
GO:0042350	GDP-L-fucose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
GO:0042352	GDP-L-fucose salvage	biological_process	The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).
GO:0042353	fucose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).
GO:0042354	L-fucose metabolic process	biological_process	The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.
GO:0042355	L-fucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
GO:0042356	GDP-4-dehydro-D-rhamnose reductase activity	molecular_function	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
GO:0042357	thiamine diphosphate metabolic process	biological_process	The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
GO:0042358	thiamine diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
GO:0042359	vitamin D metabolic process	biological_process	The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0042360	vitamin E metabolic process	biological_process	The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
GO:0042361	menaquinone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
GO:0042362	fat-soluble vitamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
GO:0042363	fat-soluble vitamin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
GO:0042364	water-soluble vitamin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.
GO:0042365	water-soluble vitamin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.
GO:0042366	cobalamin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GO:0042367	biotin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
GO:0042368	vitamin D biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0042369	vitamin D catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0042370	thiamine diphosphate dephosphorylation	biological_process	The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
GO:0042371	vitamin K biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
GO:0042372	phylloquinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
GO:0042373	vitamin K metabolic process	biological_process	The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
GO:0042374	phylloquinone metabolic process	biological_process	The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.
GO:0042376	phylloquinone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
GO:0042377	vitamin K catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
GO:0042379	chemokine receptor binding	molecular_function	Binding to a chemokine receptor.
GO:0042380	hydroxymethylbutenyl pyrophosphate reductase activity	molecular_function	Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
GO:0042381	hemolymph coagulation	biological_process	Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.
GO:0042382	paraspeckles	cellular_component	Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.
GO:0042383	sarcolemma	cellular_component	The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
GO:0042385	myosin III complex	cellular_component	A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.
GO:0042386	hemocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
GO:0042387	plasmatocyte differentiation	biological_process	The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.
GO:0042388	gibberellic acid mediated signaling pathway, G-alpha-dependent	biological_process	The series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
GO:0042389	omega-3 fatty acid desaturase activity	molecular_function	Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.
GO:0042390	gibberellic acid mediated signaling pathway, G-alpha-independent	biological_process	The series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
GO:0042391	regulation of membrane potential	biological_process	Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0042392	sphingosine-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.
GO:0042393	histone binding	molecular_function	Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.
GO:0042395	ecdysis, collagen and cuticulin-based cuticle	biological_process	The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.
GO:0042396	phosphagen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
GO:0042397	phosphagen catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
GO:0042398	cellular modified amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0042399	ectoine metabolic process	biological_process	The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
GO:0042400	ectoine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
GO:0042401	biogenic amine biosynthetic process	biological_process	The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
GO:0042402	cellular biogenic amine catabolic process	biological_process	The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
GO:0042403	thyroid hormone metabolic process	biological_process	The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
GO:0042404	thyroid hormone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
GO:0042405	nuclear inclusion body	cellular_component	An intranuclear focus at which aggregated proteins have been sequestered.
GO:0042406	extrinsic component of endoplasmic reticulum membrane	cellular_component	The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0042407	cristae formation	biological_process	The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
GO:0042409	caffeoyl-CoA O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.
GO:0042410	6-carboxyhexanoate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H+ + pimelyl-CoA.
GO:0042412	taurine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
GO:0042413	carnitine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
GO:0042414	epinephrine metabolic process	biological_process	The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
GO:0042415	norepinephrine metabolic process	biological_process	The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
GO:0042416	dopamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0042417	dopamine metabolic process	biological_process	The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0042418	epinephrine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
GO:0042419	epinephrine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
GO:0042420	dopamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0042421	norepinephrine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
GO:0042422	norepinephrine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
GO:0042423	catecholamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
GO:0042424	catecholamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
GO:0042425	choline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
GO:0042426	choline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
GO:0042427	serotonin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
GO:0042428	serotonin metabolic process	biological_process	The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
GO:0042429	serotonin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
GO:0042430	indole-containing compound metabolic process	biological_process	The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.
GO:0042431	indole metabolic process	biological_process	The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
GO:0042432	indole biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
GO:0042433	indole catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
GO:0042435	indole-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.
GO:0042436	indole-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.
GO:0042437	indoleacetic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
GO:0042438	melanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
GO:0042439	ethanolamine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it.
GO:0042440	pigment metabolic process	biological_process	The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.
GO:0042441	eye pigment metabolic process	biological_process	The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
GO:0042442	melatonin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).
GO:0042443	phenylethylamine metabolic process	biological_process	The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
GO:0042444	phenylethylamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
GO:0042445	hormone metabolic process	biological_process	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
GO:0042446	hormone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
GO:0042447	hormone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
GO:0042448	progesterone metabolic process	biological_process	The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
GO:0042450	arginine biosynthetic process via ornithine	biological_process	The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.
GO:0042451	purine nucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0042452	deoxyguanosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
GO:0042453	deoxyguanosine metabolic process	biological_process	The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
GO:0042454	ribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0042455	ribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0042457	ethylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
GO:0042458	nopaline catabolic process to proline	biological_process	The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline.
GO:0042459	octopine catabolic process to proline	biological_process	The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.
GO:0042461	photoreceptor cell development	biological_process	Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
GO:0042462	eye photoreceptor cell development	biological_process	Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
GO:0042463	ocellus photoreceptor cell development	biological_process	Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.
GO:0042464	dosage compensation by hypoactivation of X chromosome	biological_process	Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.
GO:0042465	kinesis	biological_process	The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus.
GO:0042466	chemokinesis	biological_process	A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis).
GO:0042467	orthokinesis	biological_process	The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.
GO:0042468	klinokinesis	biological_process	The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered.
GO:0042469	versicolorin reductase activity	molecular_function	Catalysis of the reduction of versicolorin A to sterigmatocystin.
GO:0042470	melanosome	cellular_component	A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
GO:0042471	ear morphogenesis	biological_process	The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
GO:0042472	inner ear morphogenesis	biological_process	The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
GO:0042473	outer ear morphogenesis	biological_process	The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.
GO:0042474	middle ear morphogenesis	biological_process	The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
GO:0042475	odontogenesis of dentin-containing tooth	biological_process	The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
GO:0042476	odontogenesis	biological_process	The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
GO:0042478	regulation of eye photoreceptor cell development	biological_process	Any process that modulates the frequency, rate or extent of eye photoreceptor development.
GO:0042479	positive regulation of eye photoreceptor cell development	biological_process	Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.
GO:0042480	negative regulation of eye photoreceptor cell development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.
GO:0042481	regulation of odontogenesis	biological_process	Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042482	positive regulation of odontogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042483	negative regulation of odontogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.
GO:0042487	regulation of odontogenesis of dentin-containing tooth	biological_process	Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	biological_process	Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
GO:0042489	negative regulation of odontogenesis of dentin-containing tooth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.
GO:0042490	mechanoreceptor differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
GO:0042491	inner ear auditory receptor cell differentiation	biological_process	The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.
GO:0042492	gamma-delta T cell differentiation	biological_process	The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
GO:0042494	detection of bacterial lipoprotein	biological_process	The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs).
GO:0042495	detection of triacyl bacterial lipopeptide	biological_process	The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups.
GO:0042496	detection of diacyl bacterial lipopeptide	biological_process	The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups.
GO:0042497	triacyl lipopeptide binding	molecular_function	Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups.
GO:0042498	diacyl lipopeptide binding	molecular_function	Binding to a lipopeptide containing a nonprotein moiety consisting of two acyl groups.
GO:0042500	aspartic endopeptidase activity, intramembrane cleaving	molecular_function	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.
GO:0042501	serine phosphorylation of STAT protein	biological_process	The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	biological_process	Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	biological_process	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
GO:0042537	benzene-containing compound metabolic process	biological_process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
GO:0042538	hyperosmotic salinity response	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0042539	hypotonic salinity response	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0042540	hemoglobin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids.
GO:0042541	hemoglobin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
GO:0042542	response to hydrogen peroxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
GO:0042543	protein N-linked glycosylation via arginine	biological_process	The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.
GO:0042544	melibiose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
GO:0042545	cell wall modification	biological_process	The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.
GO:0042546	cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0042547	cell wall modification involved in multidimensional cell growth	biological_process	The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.
GO:0042548	regulation of photosynthesis, light reaction	biological_process	Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.
GO:0042549	photosystem II stabilization	biological_process	The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.
GO:0042550	photosystem I stabilization	biological_process	The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.
GO:0042551	neuron maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
GO:0042552	myelination	biological_process	The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
GO:0042554	superoxide anion generation	biological_process	The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
GO:0042555	MCM complex	cellular_component	A hexameric protein complex required for the initiation and regulation of DNA replication.
GO:0042556	eukaryotic elongation factor-2 kinase regulator activity	molecular_function	Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.
GO:0042557	eukaryotic elongation factor-2 kinase activator activity	molecular_function	Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.
GO:0042558	pteridine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0042559	pteridine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0042560	pteridine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
GO:0042561	alpha-amyrin synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin.
GO:0042562	hormone binding	molecular_function	Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.
GO:0042564	NLS-dependent protein nuclear import complex	cellular_component	A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.
GO:0042565	RNA nuclear export complex	cellular_component	A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore.
GO:0042566	hydrogenosome	cellular_component	A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation.
GO:0042567	insulin-like growth factor ternary complex	cellular_component	A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.
GO:0042568	insulin-like growth factor binary complex	cellular_component	A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.
GO:0042571	immunoglobulin complex, circulating	cellular_component	An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.
GO:0042572	retinol metabolic process	biological_process	The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
GO:0042573	retinoic acid metabolic process	biological_process	The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
GO:0042574	retinal metabolic process	biological_process	The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
GO:0042575	DNA polymerase complex	cellular_component	A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
GO:0042577	lipid phosphatase activity	molecular_function	Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
GO:0042578	phosphoric ester hydrolase activity	molecular_function	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0042579	microbody	cellular_component	Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
GO:0042580	mannosome	cellular_component	A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction.
GO:0042581	specific granule	cellular_component	Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
GO:0042582	azurophil granule	cellular_component	Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
GO:0042583	chromaffin granule	cellular_component	Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.
GO:0042584	chromaffin granule membrane	cellular_component	The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.
GO:0042585	germinal vesicle	cellular_component	The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
GO:0042586	peptide deformylase activity	molecular_function	Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.
GO:0042587	glycogen granule	cellular_component	Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.
GO:0042588	zymogen granule	cellular_component	A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.
GO:0042589	zymogen granule membrane	cellular_component	The lipid bilayer surrounding a zymogen granule.
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	biological_process	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
GO:0042592	homeostatic process	biological_process	Any biological process involved in the maintenance of an internal steady state.
GO:0042593	glucose homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
GO:0042594	response to starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
GO:0042595	behavioral response to starvation	biological_process	Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.
GO:0042596	fear response	biological_process	The response of an organism to a perceived external threat.
GO:0042597	periplasmic space	cellular_component	The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
GO:0042599	lamellar body	cellular_component	A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
GO:0042600	egg chorion	cellular_component	A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.
GO:0042601	endospore-forming forespore	cellular_component	Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions.
GO:0042602	riboflavin reductase (NADPH) activity	molecular_function	Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
GO:0042603	capsule	cellular_component	A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.
GO:0042605	peptide antigen binding	molecular_function	Binding to an antigen peptide.
GO:0042608	T cell receptor binding	molecular_function	Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells.
GO:0042609	CD4 receptor binding	molecular_function	Binding to a CD4, a receptor found on the surface of T cells, monocytes and macrophages.
GO:0042610	CD8 receptor binding	molecular_function	Binding to a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes.
GO:0042611	MHC protein complex	cellular_component	A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
GO:0042612	MHC class I protein complex	cellular_component	A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
GO:0042613	MHC class II protein complex	cellular_component	A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.
GO:0042614	CD70 receptor binding	molecular_function	Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.
GO:0042615	CD154 receptor binding	molecular_function	Binding to CD154, a receptor found on the surface of some activated lymphocytes.
GO:0042617	paclitaxel biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.
GO:0042618	poly-hydroxybutyrate metabolic process	biological_process	The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.
GO:0042619	poly-hydroxybutyrate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.
GO:0042620	poly(3-hydroxyalkanoate) metabolic process	biological_process	The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
GO:0042621	poly(3-hydroxyalkanoate) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
GO:0042622	photoreceptor outer segment membrane	cellular_component	The membrane surrounding the outer segment of a vertebrate photoreceptor.
GO:0042625	ATPase-coupled ion transmembrane transporter activity	molecular_function	Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.
GO:0042626	ATPase-coupled transmembrane transporter activity	molecular_function	Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
GO:0042627	chylomicron	cellular_component	A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
GO:0042628	mating plug formation	biological_process	The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.
GO:0042629	mast cell granule	cellular_component	Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase.
GO:0042630	behavioral response to water deprivation	biological_process	Any process that results in a change in the behavior of an organism as a result of deprivation of water.
GO:0042631	cellular response to water deprivation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.
GO:0042632	cholesterol homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
GO:0042633	hair cycle	biological_process	The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
GO:0042634	regulation of hair cycle	biological_process	Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
GO:0042635	positive regulation of hair cycle	biological_process	Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
GO:0042636	negative regulation of hair cycle	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
GO:0042637	catagen	biological_process	The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.
GO:0042638	exogen	biological_process	The shedding phase of the hair cycle.
GO:0042639	telogen	biological_process	The resting phase of hair cycle.
GO:0042640	anagen	biological_process	The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.
GO:0042641	actomyosin	cellular_component	Any complex of actin, myosin, and accessory proteins.
GO:0042642	actomyosin, myosin complex part	cellular_component	The myosin part of any complex of actin, myosin, and accessory proteins.
GO:0042644	chloroplast nucleoid	cellular_component	The region of a chloroplast to which the DNA is confined.
GO:0042645	mitochondrial nucleoid	cellular_component	The region of a mitochondrion to which the DNA is confined.
GO:0042646	plastid nucleoid	cellular_component	The region of a plastid to which the DNA is confined.
GO:0042647	proplastid nucleoid	cellular_component	The region of a proplastid to which the DNA is confined.
GO:0042648	chloroplast chromosome	cellular_component	A circular DNA molecule containing chloroplast encoded genes.
GO:0042649	prothylakoid	cellular_component	Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light.
GO:0042650	prothylakoid membrane	cellular_component	The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes.
GO:0042651	thylakoid membrane	cellular_component	The pigmented membrane of any thylakoid.
GO:0042652	mitochondrial respiratory chain complex I, peripheral segment	cellular_component	The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.
GO:0042653	mitochondrial respiratory chain complex I, membrane segment	cellular_component	The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.
GO:0042654	ecdysis-triggering hormone receptor activity	molecular_function	Combining with ecdysis-triggering hormone to initiate a change in cell activity.
GO:0042656	JUN kinase kinase kinase kinase activity	molecular_function	Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).
GO:0042657	MHC class II protein binding, via lateral surface	molecular_function	Binding to the lateral surface of major histocompatibility complex class II molecules.
GO:0042658	MHC class II protein binding, via antigen binding groove	molecular_function	Binding to the antigen binding groove of major histocompatibility complex class II molecules.
GO:0042659	regulation of cell fate specification	biological_process	Any process that mediates the adoption of a specific fate by a cell.
GO:0042660	positive regulation of cell fate specification	biological_process	Any process that activates or enables a cell to adopt a specific fate.
GO:0042661	regulation of mesodermal cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.
GO:0042662	negative regulation of mesodermal cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.
GO:0042663	regulation of endodermal cell fate specification	biological_process	Any process that mediates the specification of a cell into an endoderm cell.
GO:0042664	negative regulation of endodermal cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.
GO:0042665	regulation of ectodermal cell fate specification	biological_process	Any process that mediates the specification of a cell into an ectoderm cell.
GO:0042666	negative regulation of ectodermal cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.
GO:0042667	auditory receptor cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0042668	auditory receptor cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0042669	regulation of inner ear auditory receptor cell fate specification	biological_process	Any process that mediates the specification of a cell into an auditory hair cell.
GO:0042670	retinal cone cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.
GO:0042671	retinal cone cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0042672	retinal cone cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0042673	regulation of retinal cone cell fate specification	biological_process	Any process that mediates the specification of a cell into a retinal cone cell.
GO:0042675	compound eye cone cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.
GO:0042676	compound eye cone cell fate commitment	biological_process	The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.
GO:0042679	compound eye cone cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0042680	compound eye cone cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0042682	regulation of compound eye cone cell fate specification	biological_process	Any process that mediates the specification of a cell into a compound eye cone cell.
GO:0042683	negative regulation of compound eye cone cell fate specification	biological_process	Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.
GO:0042684	cardioblast cell fate commitment	biological_process	The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0042685	cardioblast cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0042686	regulation of cardioblast cell fate specification	biological_process	Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0042688	crystal cell differentiation	biological_process	The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
GO:0042689	regulation of crystal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of crystal cell differentiation.
GO:0042690	negative regulation of crystal cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.
GO:0042691	positive regulation of crystal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.
GO:0042692	muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
GO:0042693	muscle cell fate commitment	biological_process	The process in which the cellular identity of muscle cells is acquired and determined.
GO:0042694	muscle cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0042695	thelarche	biological_process	The beginning of development of the breasts in the female.
GO:0042696	menarche	biological_process	The beginning of the menstrual cycle; the first menstrual cycle in an individual.
GO:0042697	menopause	biological_process	Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.
GO:0042698	ovulation cycle	biological_process	The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
GO:0042699	follicle-stimulating hormone signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by follicle-stimulating hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0042700	luteinizing hormone signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by luteinizing hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0042701	progesterone secretion	biological_process	The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
GO:0042702	uterine wall growth	biological_process	The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.
GO:0042703	menstruation	biological_process	The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.
GO:0042704	uterine wall breakdown	biological_process	The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.
GO:0042705	ocellus photoreceptor cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.
GO:0042706	eye photoreceptor cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
GO:0042707	ocellus photoreceptor cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
GO:0042709	succinate-CoA ligase complex	cellular_component	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.
GO:0042710	biofilm formation	biological_process	A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0042711	maternal behavior	biological_process	Female behaviors associated with the care and rearing of offspring.
GO:0042712	paternal behavior	biological_process	Male behaviors associated with the care and rearing offspring.
GO:0042713	sperm ejaculation	biological_process	The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
GO:0042714	dosage compensation complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.
GO:0042716	plasma membrane-derived chromatophore	cellular_component	A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria.
GO:0042717	plasma membrane-derived chromatophore membrane	cellular_component	The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles.
GO:0042718	yolk granule	cellular_component	Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.
GO:0042719	mitochondrial intermembrane space protein transporter complex	cellular_component	Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
GO:0042720	mitochondrial inner membrane peptidase complex	cellular_component	Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
GO:0042721	TIM22 mitochondrial import inner membrane insertion complex	cellular_component	A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.
GO:0042722	alpha-beta T cell activation by superantigen	biological_process	The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.
GO:0042723	thiamine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
GO:0042724	thiamine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.
GO:0042725	thiamine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.
GO:0042726	flavin-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
GO:0042727	flavin-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
GO:0042728	flavin-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
GO:0042729	DASH complex	cellular_component	A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
GO:0042730	fibrinolysis	biological_process	A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
GO:0042731	PH domain binding	molecular_function	Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.
GO:0042732	D-xylose metabolic process	biological_process	The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.
GO:0042733	embryonic digit morphogenesis	biological_process	The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
GO:0042734	presynaptic membrane	cellular_component	A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
GO:0042735	endosperm protein body	cellular_component	A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins.
GO:0042736	NADH kinase activity	molecular_function	Catalysis of the reaction: ATP + NADH = ADP + 2 H+ + NADPH.
GO:0042740	exogenous antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.
GO:0042741	endogenous antibiotic catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.
GO:0042742	defense response to bacterium	biological_process	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
GO:0042743	hydrogen peroxide metabolic process	biological_process	The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
GO:0042744	hydrogen peroxide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
GO:0042745	circadian sleep/wake cycle	biological_process	The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
GO:0042746	circadian sleep/wake cycle, wakefulness	biological_process	The part of the circadian sleep/wake cycle where the organism is not asleep.
GO:0042747	circadian sleep/wake cycle, REM sleep	biological_process	A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
GO:0042748	circadian sleep/wake cycle, non-REM sleep	biological_process	All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.
GO:0042749	regulation of circadian sleep/wake cycle	biological_process	Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.
GO:0042750	hibernation	biological_process	Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.
GO:0042751	estivation	biological_process	Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.
GO:0042752	regulation of circadian rhythm	biological_process	Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
GO:0042753	positive regulation of circadian rhythm	biological_process	Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
GO:0042754	negative regulation of circadian rhythm	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
GO:0042755	eating behavior	biological_process	The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
GO:0042756	drinking behavior	biological_process	The specific behavior of an organism relating to the intake of liquids, especially water.
GO:0042757	giant axon	cellular_component	Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses.
GO:0042758	long-chain fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0042759	long-chain fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a long-chain fatty acid, a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0042760	very long-chain fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
GO:0042761	very long-chain fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
GO:0042762	regulation of sulfur metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
GO:0042763	intracellular immature spore	cellular_component	A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants.
GO:0042764	ascospore-type prospore	cellular_component	An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.
GO:0042765	GPI-anchor transamidase complex	cellular_component	An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.
GO:0042767	ecdysteroid 22-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.
GO:0042768	ecdysteroid 2-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of an ecdysteroid at carbon position 2.
GO:0042770	signal transduction in response to DNA damage	biological_process	A cascade of processes induced by the detection of DNA damage within a cell.
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
GO:0042772	DNA damage response, signal transduction resulting in transcription	biological_process	A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.
GO:0042773	ATP synthesis coupled electron transport	biological_process	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.
GO:0042774	plasma membrane ATP synthesis coupled electron transport	biological_process	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane.
GO:0042775	mitochondrial ATP synthesis coupled electron transport	biological_process	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.
GO:0042776	proton motive force-driven mitochondrial ATP synthesis	biological_process	The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
GO:0042777	proton motive force-driven plasma membrane ATP synthesis	biological_process	The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
GO:0042778	tRNA end turnover	biological_process	The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.
GO:0042780	tRNA 3'-end processing	biological_process	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
GO:0042781	3'-tRNA processing endoribonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
GO:0042783	evasion of host immune response	biological_process	A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042784	evasion of host immune response via modulation of host complement system	biological_process	Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042785	evasion of host immune response via modulation of host cytokine network	biological_process	Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042786	evasion of host immune response via modulation of host antigen processing and presentation	biological_process	Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0042788	polysomal ribosome	cellular_component	A ribosome bound to mRNA that forms part of a polysome.
GO:0042789	mRNA transcription by RNA polymerase II	biological_process	The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	biological_process	The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.
GO:0042791	5S class rRNA transcription by RNA polymerase III	biological_process	The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.
GO:0042793	plastid transcription	biological_process	The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.
GO:0042794	plastid rRNA transcription	biological_process	The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.
GO:0042795	snRNA transcription by RNA polymerase II	biological_process	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
GO:0042796	snRNA transcription by RNA polymerase III	biological_process	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
GO:0042797	tRNA transcription by RNA polymerase III	biological_process	The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
GO:0042799	histone H4K20 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.
GO:0042800	histone H3K4 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of up to three methyl groups to the lysine residue at position 4 of the histone H3 protein.
GO:0042802	identical protein binding	molecular_function	Binding to an identical protein or proteins.
GO:0042803	protein homodimerization activity	molecular_function	Binding to an identical protein to form a homodimer.
GO:0042805	actinin binding	molecular_function	Binding to actinin, any member of a family of proteins that crosslink F-actin.
GO:0042806	fucose binding	molecular_function	Binding to fucose, the pentose 6-deoxygalactose.
GO:0042807	central vacuole	cellular_component	A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.
GO:0042809	nuclear vitamin D receptor binding	molecular_function	Binding to a nuclear vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.
GO:0042810	pheromone metabolic process	biological_process	The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
GO:0042811	pheromone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
GO:0042812	pheromone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
GO:0042813	Wnt receptor activity	molecular_function	Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0042814	monopolar cell growth	biological_process	Polarized growth from one end of a cell.
GO:0042815	bipolar cell growth	biological_process	The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.
GO:0042816	vitamin B6 metabolic process	biological_process	The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
GO:0042817	pyridoxal metabolic process	biological_process	The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0042818	pyridoxamine metabolic process	biological_process	The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
GO:0042819	vitamin B6 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
GO:0042820	vitamin B6 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
GO:0042821	pyridoxal biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.
GO:0042822	pyridoxal phosphate metabolic process	biological_process	The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
GO:0042823	pyridoxal phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
GO:0042824	MHC class I peptide loading complex	cellular_component	A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
GO:0042825	TAP complex	cellular_component	A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.
GO:0042826	histone deacetylase binding	molecular_function	Binding to histone deacetylase.
GO:0042827	platelet dense granule	cellular_component	Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.
GO:0042832	defense response to protozoan	biological_process	Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.
GO:0042834	peptidoglycan binding	molecular_function	Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
GO:0042835	BRE binding	molecular_function	Binding to a BRE RNA element (Bruno response element).
GO:0042836	D-glucarate metabolic process	biological_process	The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.
GO:0042837	D-glucarate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.
GO:0042838	D-glucarate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.
GO:0042839	D-glucuronate metabolic process	biological_process	The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate.
GO:0042840	D-glucuronate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.
GO:0042841	D-glucuronate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.
GO:0042842	D-xylose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.
GO:0042843	D-xylose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.
GO:0042844	glycol metabolic process	biological_process	The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
GO:0042845	glycol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
GO:0042846	glycol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
GO:0042847	sorbose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
GO:0042848	sorbose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
GO:0042849	L-sorbose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
GO:0042850	L-sorbose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.
GO:0042851	L-alanine metabolic process	biological_process	The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
GO:0042852	L-alanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
GO:0042853	L-alanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
GO:0042854	eugenol metabolic process	biological_process	The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
GO:0042855	eugenol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
GO:0042856	eugenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
GO:0042857	chrysobactin metabolic process	biological_process	The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
GO:0042858	chrysobactin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
GO:0042859	chrysobactin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
GO:0042860	achromobactin metabolic process	biological_process	The chemical reactions and pathways involving achromobactin, a citrate siderophore.
GO:0042861	achromobactin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.
GO:0042862	achromobactin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.
GO:0042863	pyochelin metabolic process	biological_process	The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
GO:0042864	pyochelin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
GO:0042865	pyochelin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
GO:0042866	pyruvate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.
GO:0042867	pyruvate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.
GO:0042868	antisense RNA metabolic process	biological_process	The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.
GO:0042869	aldarate transmembrane transport	biological_process	The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042870	D-glucarate transmembrane transport	biological_process	The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042873	aldonate transmembrane transport	biological_process	The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042874	D-glucuronate transmembrane transport	biological_process	The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042875	D-galactonate transmembrane transport	biological_process	The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042876	aldarate transmembrane transporter activity	molecular_function	Enables the transfer of aldarate from one side of a membrane to the other.
GO:0042878	D-glucarate transmembrane transporter activity	molecular_function	Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other.
GO:0042879	aldonate transmembrane transporter activity	molecular_function	Enables the transfer of aldonate from one side of a membrane to the other.
GO:0042880	D-glucuronate transmembrane transporter activity	molecular_function	Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.
GO:0042881	D-galactonate transmembrane transporter activity	molecular_function	Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other.
GO:0042882	L-arabinose transmembrane transport	biological_process	The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042883	cysteine transport	biological_process	The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042884	microcin transport	biological_process	The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042885	microcin B17 transport	biological_process	The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042886	amide transport	biological_process	The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042887	amide transmembrane transporter activity	molecular_function	Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.
GO:0042888	molybdenum ion transmembrane transporter activity	molecular_function	Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other.
GO:0042892	chloramphenicol transmembrane transport	biological_process	The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other.
GO:0042893	polymyxin transport	biological_process	The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042894	fosmidomycin transport	biological_process	The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042896	chloramphenicol transmembrane transporter activity	molecular_function	Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other.
GO:0042897	polymyxin transmembrane transporter activity	molecular_function	Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.
GO:0042898	fosmidomycin transmembrane transporter activity	molecular_function	Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.
GO:0042899	arabinan transmembrane transport	biological_process	The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0042900	arabinose transmembrane transporter activity	molecular_function	Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other.
GO:0042901	arabinan transmembrane transporter activity	molecular_function	Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other.
GO:0042902	peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein	biological_process	The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
GO:0042903	tubulin deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.
GO:0042904	9-cis-retinoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.
GO:0042905	9-cis-retinoic acid metabolic process	biological_process	The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.
GO:0042906	xanthine transport	biological_process	The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.
GO:0042907	xanthine transmembrane transporter activity	molecular_function	Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.
GO:0042908	xenobiotic transport	biological_process	The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0042910	xenobiotic transmembrane transporter activity	molecular_function	Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0042912	colicin transmembrane transporter activity	molecular_function	Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
GO:0042913	group A colicin transmembrane transporter activity	molecular_function	Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other.
GO:0042914	colicin transport	biological_process	The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
GO:0042915	group A colicin transport	biological_process	The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042918	alkanesulfonate transport	biological_process	The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical.
GO:0042919	benzoate transport	biological_process	The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042920	3-hydroxyphenylpropionic acid transmembrane transport	biological_process	The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other.
GO:0042921	glucocorticoid receptor signaling pathway	biological_process	The series of molecular signals initiated by glucocorticoid binding to its receptor.
GO:0042922	neuromedin U receptor binding	molecular_function	Binding to one or more specific sites on a neuromedin U receptor.
GO:0042923	neuropeptide binding	molecular_function	Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
GO:0042924	neuromedin U binding	molecular_function	Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.
GO:0042925	benzoate transmembrane transporter activity	molecular_function	Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.
GO:0042926	3-hydroxyphenylpropionic acid transmembrane transporter activity	molecular_function	Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other.
GO:0042928	ferrichrome import into cell	biological_process	A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
GO:0042929	ferrichrome transmembrane transporter activity	molecular_function	Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
GO:0042930	enterobactin transport	biological_process	The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042931	enterobactin transmembrane transporter activity	molecular_function	Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.
GO:0042932	chrysobactin transport	biological_process	The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042933	chrysobactin transmembrane transporter activity	molecular_function	Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.
GO:0042934	achromobactin transmembrane transporter activity	molecular_function	Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other.
GO:0042935	achromobactin transport	biological_process	The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042937	tripeptide transmembrane transporter activity	molecular_function	Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.
GO:0042938	dipeptide transport	biological_process	The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042939	tripeptide transport	biological_process	The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042940	D-amino acid transport	biological_process	The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042941	D-alanine transport	biological_process	The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042942	D-serine transport	biological_process	The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042943	D-amino acid transmembrane transporter activity	molecular_function	Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.
GO:0042944	D-alanine transmembrane transporter activity	molecular_function	Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.
GO:0042945	D-serine transmembrane transporter activity	molecular_function	Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.
GO:0042946	glucoside transport	biological_process	The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.
GO:0042947	glucoside transmembrane transporter activity	molecular_function	Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.
GO:0042948	salicin transport	biological_process	The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042949	arbutin transport	biological_process	The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042950	salicin transmembrane transporter activity	molecular_function	Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other.
GO:0042951	arbutin transmembrane transporter activity	molecular_function	Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.
GO:0042952	beta-ketoadipate pathway	biological_process	A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.
GO:0042953	lipoprotein transport	biological_process	The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042955	dextrin transport	biological_process	The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042956	maltodextrin transmembrane transport	biological_process	The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane.
GO:0042957	dextrin transmembrane transporter activity	molecular_function	Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.
GO:0042958	maltodextrin transmembrane transporter activity	molecular_function	Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other.
GO:0042959	alkanesulfonate transmembrane transporter activity	molecular_function	Enables the directed movement of alkanesulfonate from one side of a membrane to the other.
GO:0042960	antimonite secondary active transmembrane transporter activity	molecular_function	Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0042961	ATPase-coupled antimonite transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).
GO:0042962	acridine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).
GO:0042966	biotin carboxyl carrier protein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase.
GO:0042968	homoserine transport	biological_process	The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042970	homoserine transmembrane transporter activity	molecular_function	Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
GO:0042972	licheninase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.
GO:0042973	glucan endo-1,3-beta-D-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.
GO:0042974	nuclear retinoic acid receptor binding	molecular_function	Binding to a nuclear retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.
GO:0042975	peroxisome proliferator activated receptor binding	molecular_function	Binding to a peroxisome proliferator activated receptor, alpha, beta or gamma.
GO:0042976	activation of Janus kinase activity	biological_process	The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
GO:0042978	ornithine decarboxylase activator activity	molecular_function	Binds to and increases ornithine decarboxylase activity.
GO:0042979	ornithine decarboxylase regulator activity	molecular_function	Binds to and modulates the activity of the enzyme ornithine decarboxylase.
GO:0042981	regulation of apoptotic process	biological_process	Any process that modulates the occurrence or rate of cell death by apoptotic process.
GO:0042982	amyloid precursor protein metabolic process	biological_process	The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
GO:0042983	amyloid precursor protein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
GO:0042984	regulation of amyloid precursor protein biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.
GO:0042987	amyloid precursor protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
GO:0042988	X11-like protein binding	molecular_function	Binding to X11-like protein, a neuron-specific adaptor protein.
GO:0042989	sequestering of actin monomers	biological_process	The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.
GO:0042994	cytoplasmic sequestering of transcription factor	biological_process	The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
GO:0042995	cell projection	cellular_component	A prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0042996	regulation of Golgi to plasma membrane protein transport	biological_process	Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	biological_process	Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GO:0043001	Golgi to plasma membrane protein transport	biological_process	The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
GO:0043005	neuron projection	cellular_component	A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:0043007	maintenance of rDNA	biological_process	Any process involved in sustaining the fidelity and copy number of rDNA repeats.
GO:0043008	ATP-dependent protein binding	molecular_function	Binding to a protein or protein complex using energy from ATP hydrolysis.
GO:0043009	chordate embryonic development	biological_process	The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
GO:0043010	camera-type eye development	biological_process	The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
GO:0043011	myeloid dendritic cell differentiation	biological_process	The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.
GO:0043012	regulation of fusion of sperm to egg plasma membrane	biological_process	Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.
GO:0043013	negative regulation of fusion of sperm to egg plasma membrane	biological_process	Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.
GO:0043014	alpha-tubulin binding	molecular_function	Binding to the microtubule constituent protein alpha-tubulin.
GO:0043015	gamma-tubulin binding	molecular_function	Binding to the microtubule constituent protein gamma-tubulin.
GO:0043020	NADPH oxidase complex	cellular_component	A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
GO:0043021	ribonucleoprotein complex binding	molecular_function	Binding to a complex of RNA and protein.
GO:0043022	ribosome binding	molecular_function	Binding to a ribosome.
GO:0043023	ribosomal large subunit binding	molecular_function	Binding to a large ribosomal subunit.
GO:0043024	ribosomal small subunit binding	molecular_function	Binding to a small ribosomal subunit.
GO:0043025	neuronal cell body	cellular_component	The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	molecular_function	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	molecular_function	Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.
GO:0043029	T cell homeostasis	biological_process	The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0043030	regulation of macrophage activation	biological_process	Any process that modulates the frequency or rate of macrophage activation.
GO:0043031	negative regulation of macrophage activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
GO:0043032	positive regulation of macrophage activation	biological_process	Any process that stimulates, induces or increases the rate of macrophage activation.
GO:0043033	isoamylase complex	cellular_component	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages.
GO:0043034	costamere	cellular_component	Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.
GO:0043035	chromatin insulator sequence binding	molecular_function	Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
GO:0043036	starch grain	cellular_component	Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
GO:0043038	amino acid activation	biological_process	The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.
GO:0043039	tRNA aminoacylation	biological_process	The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
GO:0043040	tRNA aminoacylation for nonribosomal peptide biosynthetic process	biological_process	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis.
GO:0043041	amino acid activation for nonribosomal peptide biosynthetic process	biological_process	Activation of an amino acid for incorporation into a peptide by a nonribosomal process.
GO:0043042	amino acid adenylylation by nonribosomal peptide synthase	biological_process	Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.
GO:0043043	peptide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.
GO:0043045	post-fertilization epigenetic regulation of gene expression	biological_process	A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation.
GO:0043047	single-stranded telomeric DNA binding	molecular_function	Binding to single-stranded telomere-associated DNA.
GO:0043048	dolichyl monophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.
GO:0043049	otic placode formation	biological_process	The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.
GO:0043050	pharyngeal pumping	biological_process	The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
GO:0043051	regulation of pharyngeal pumping	biological_process	Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
GO:0043052	thermotaxis	biological_process	The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
GO:0043053	dauer entry	biological_process	Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.
GO:0043054	dauer exit	biological_process	Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.
GO:0043055	maintenance of dauer	biological_process	Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development.
GO:0043056	forward locomotion	biological_process	Anterior movement of an organism, following the direction of the head of the animal.
GO:0043057	backward locomotion	biological_process	Posterior movement of an organism, e.g. following the direction of the tail of an animal.
GO:0043058	regulation of backward locomotion	biological_process	Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.
GO:0043059	regulation of forward locomotion	biological_process	Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.
GO:0043060	meiotic metaphase I homologous chromosome alignment	biological_process	A cell cycle process whereby homlogous chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator) by the spindle machinery and centromere/kinetochore arrangement during meiosis I chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
GO:0043061	meiotic metaphase II chromosome alignment	biological_process	A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiosis II chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
GO:0043062	extracellular structure organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
GO:0043063	intercellular bridge organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.
GO:0043065	positive regulation of apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
GO:0043066	negative regulation of apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
GO:0043067	regulation of programmed cell death	biological_process	Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043068	positive regulation of programmed cell death	biological_process	Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043069	negative regulation of programmed cell death	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043073	germ cell nucleus	cellular_component	The nucleus of a germ cell, a reproductive cell in multicellular organisms.
GO:0043076	megasporocyte nucleus	cellular_component	The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.
GO:0043077	initiation of acetate catabolic process	biological_process	The activation of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0043078	polar nucleus	cellular_component	Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus.
GO:0043079	antipodal cell nucleus	cellular_component	The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents.
GO:0043082	megagametophyte egg cell nucleus	cellular_component	The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo.
GO:0043083	synaptic cleft	cellular_component	The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
GO:0043084	penile erection	biological_process	The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
GO:0043085	positive regulation of catalytic activity	biological_process	Any process that activates or increases the activity of an enzyme.
GO:0043086	negative regulation of catalytic activity	biological_process	Any process that stops or reduces the activity of an enzyme.
GO:0043087	regulation of GTPase activity	biological_process	Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0043090	amino acid import	biological_process	The directed movement of amino acids into a cell or organelle.
GO:0043093	FtsZ-dependent cytokinesis	biological_process	A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
GO:0043094	cellular metabolic compound salvage	biological_process	Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells.
GO:0043095	regulation of GTP cyclohydrolase I activity	biological_process	Any process that modulates the activity of the enzyme GTP cyclohydrolase I.
GO:0043096	purine nucleobase salvage	biological_process	Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.
GO:0043097	pyrimidine nucleoside salvage	biological_process	Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.
GO:0043098	purine deoxyribonucleoside salvage	biological_process	Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.
GO:0043099	pyrimidine deoxyribonucleoside salvage	biological_process	Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis.
GO:0043100	pyrimidine nucleobase salvage	biological_process	Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.
GO:0043101	purine-containing compound salvage	biological_process	Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
GO:0043102	amino acid salvage	biological_process	Any process which produces an amino acid from derivatives of it, without de novo synthesis.
GO:0043103	hypoxanthine salvage	biological_process	Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.
GO:0043104	positive regulation of GTP cyclohydrolase I activity	biological_process	Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I.
GO:0043105	negative regulation of GTP cyclohydrolase I activity	biological_process	Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I.
GO:0043107	type IV pilus-dependent motility	biological_process	Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.
GO:0043108	pilus retraction	biological_process	The process of withdrawing a pilus back into a cell.
GO:0043110	rDNA spacer replication fork barrier binding	molecular_function	Binding to replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.
GO:0043111	replication fork arrest	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
GO:0043112	receptor metabolic process	biological_process	The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0043113	receptor clustering	biological_process	The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
GO:0043114	regulation of vascular permeability	biological_process	Any process that modulates the extent to which blood vessels can be pervaded by fluid.
GO:0043115	precorrin-2 dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + precorrin-2 = 2 H+ + NADH + sirohydrochlorin.
GO:0043116	negative regulation of vascular permeability	biological_process	Any process that reduces the extent to which blood vessels can be pervaded by fluid.
GO:0043117	positive regulation of vascular permeability	biological_process	Any process that increases the extent to which blood vessels can be pervaded by fluid.
GO:0043120	tumor necrosis factor binding	molecular_function	Binding to tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
GO:0043121	neurotrophin binding	molecular_function	Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
GO:0043122	regulation of canonical NF-kappaB signal transduction	biological_process	Any process that modulates the canonical NF-kappaB signaling cascade.
GO:0043123	positive regulation of canonical NF-kappaB signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of a canonical  NF-kappaB signaling cascade.
GO:0043124	negative regulation of canonical NF-kappaB signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
GO:0043125	ErbB-3 class receptor binding	molecular_function	Binding to the protein-tyrosine kinase receptor ErbB-3/HER3.
GO:0043129	surfactant homeostasis	biological_process	Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid.
GO:0043130	ubiquitin binding	molecular_function	Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
GO:0043131	erythrocyte enucleation	biological_process	The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.
GO:0043132	NAD transport	biological_process	The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
GO:0043133	hindgut contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.
GO:0043134	regulation of hindgut contraction	biological_process	Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
GO:0043135	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity	molecular_function	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.
GO:0043136	glycerol-3-phosphatase activity	molecular_function	Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
GO:0043137	DNA replication, removal of RNA primer	biological_process	Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
GO:0043138	3'-5' DNA helicase activity	molecular_function	Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.
GO:0043139	5'-3' DNA helicase activity	molecular_function	Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
GO:0043143	regulation of translation by machinery localization	biological_process	Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.
GO:0043144	sno(s)RNA processing	biological_process	Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea).
GO:0043145	sno(s)RNA 3'-end cleavage	biological_process	The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.
GO:0043149	stress fiber assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.
GO:0043150	DNA synthesis involved in double-strand break repair via homologous recombination	biological_process	The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.
GO:0043151	DNA synthesis involved in double-strand break repair via single-strand annealing	biological_process	The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.
GO:0043152	induction of bacterial agglutination	biological_process	Any process in which infecting bacteria are clumped together by a host organism.
GO:0043153	entrainment of circadian clock by photoperiod	biological_process	The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
GO:0043155	negative regulation of photosynthesis, light reaction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.
GO:0043157	response to cation stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
GO:0043158	heterocyst development	biological_process	The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria.
GO:0043159	acrosomal matrix	cellular_component	A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.
GO:0043160	acrosomal lumen	cellular_component	The volume enclosed within the acrosome membrane.
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
GO:0043163	cell envelope organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.
GO:0043164	Gram-negative-bacterium-type cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.
GO:0043165	Gram-negative-bacterium-type cell outer membrane assembly	biological_process	The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
GO:0043167	ion binding	molecular_function	Binding to an ion, a charged atoms or groups of atoms.
GO:0043168	anion binding	molecular_function	Binding to an anion, a charged atom or group of atoms with a net negative charge.
GO:0043169	cation binding	molecular_function	Binding to a cation, a charged atom or group of atoms with a net positive charge.
GO:0043170	macromolecule metabolic process	biological_process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043171	peptide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
GO:0043173	nucleotide salvage	biological_process	Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
GO:0043174	nucleoside salvage	biological_process	Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.
GO:0043175	RNA polymerase core enzyme binding	molecular_function	Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
GO:0043176	amine binding	molecular_function	Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.
GO:0043177	organic acid binding	molecular_function	Binding to an organic acid, any acidic compound containing carbon in covalent linkage.
GO:0043178	alcohol binding	molecular_function	Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
GO:0043179	rhythmic excitation	biological_process	Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.
GO:0043180	rhythmic inhibition	biological_process	Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.
GO:0043181	vacuolar sequestering	biological_process	The process of transporting a substance into, and confining within, a vacuole.
GO:0043182	vacuolar sequestering of sodium ion	biological_process	The process of transporting sodium ions into, and confining within, a vacuole.
GO:0043183	vascular endothelial growth factor receptor 1 binding	molecular_function	Binding to a vascular endothelial growth factor receptor 1.
GO:0043184	vascular endothelial growth factor receptor 2 binding	molecular_function	Binding to a vascular endothelial growth factor receptor 2.
GO:0043185	vascular endothelial growth factor receptor 3 binding	molecular_function	Binding to a vascular endothelial growth factor receptor 3.
GO:0043186	P granule	cellular_component	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.
GO:0043188	cell septum edging	cellular_component	The cell wall material that surrounds the septum in fungal cells.
GO:0043189	H4/H2A histone acetyltransferase complex	cellular_component	A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.
GO:0043190	ATP-binding cassette (ABC) transporter complex	cellular_component	A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
GO:0043194	axon initial segment	cellular_component	Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
GO:0043195	terminal bouton	cellular_component	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
GO:0043196	varicosity	cellular_component	Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
GO:0043197	dendritic spine	cellular_component	A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
GO:0043198	dendritic shaft	cellular_component	Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
GO:0043199	sulfate binding	molecular_function	Binding to sulfate, SO4(2-), a negatively charged small molecule.
GO:0043200	response to amino acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
GO:0043201	response to leucine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
GO:0043202	lysosomal lumen	cellular_component	The volume enclosed within the lysosomal membrane.
GO:0043203	axon hillock	cellular_component	Portion of the neuronal cell soma from which the axon originates.
GO:0043204	perikaryon	cellular_component	The portion of the cell soma (neuronal cell body) that excludes the nucleus.
GO:0043207	response to external biotic stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
GO:0043208	glycosphingolipid binding	molecular_function	Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
GO:0043209	myelin sheath	cellular_component	An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
GO:0043210	alkanesulfonate binding	molecular_function	Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
GO:0043211	ABC-type carbohydrate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.
GO:0043212	carbohydrate-exporting ABC transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out).
GO:0043213	bacteriocin transport	biological_process	The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
GO:0043214	ABC-type bacteriocin transporter activity	molecular_function	Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate.
GO:0043215	daunorubicin transport	biological_process	The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043217	myelin maintenance	biological_process	The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.
GO:0043218	compact myelin	cellular_component	The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.
GO:0043219	lateral loop	cellular_component	Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.
GO:0043220	Schmidt-Lanterman incisure	cellular_component	Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.
GO:0043221	SMC family protein binding	molecular_function	Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.
GO:0043223	cytoplasmic SCF ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
GO:0043224	nuclear SCF ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in).
GO:0043226	organelle	cellular_component	Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043227	membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043228	non-membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043229	intracellular organelle	cellular_component	Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043230	extracellular organelle	cellular_component	Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
GO:0043231	intracellular membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043232	intracellular non-membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043233	organelle lumen	cellular_component	The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GO:0043235	receptor complex	cellular_component	Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0043236	laminin binding	molecular_function	Binding to a laminin, a major glycoprotein constituent of the basement membrane of cells.
GO:0043237	laminin-1 binding	molecular_function	Binding to laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.
GO:0043240	Fanconi anaemia nuclear complex	cellular_component	A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
GO:0043242	negative regulation of protein-containing complex disassembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GO:0043243	positive regulation of protein-containing complex disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GO:0043244	regulation of protein-containing complex disassembly	biological_process	Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GO:0043245	extraorganismal space	cellular_component	The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms.
GO:0043246	megasome	cellular_component	Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.
GO:0043247	telomere maintenance in response to DNA damage	biological_process	Any process that occur in response to the presence of critically short or damaged telomeres.
GO:0043248	proteasome assembly	biological_process	The aggregation, arrangement and bonding together of a mature, active proteasome complex.
GO:0043249	erythrocyte maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.
GO:0043250	sodium-dependent organic anion transmembrane transporter activity	molecular_function	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.
GO:0043251	sodium-dependent organic anion transport	biological_process	The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043252	sodium-independent organic anion transport	biological_process	The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043253	chloroplast ribosome	cellular_component	A ribosome contained within a chloroplast.
GO:0043254	regulation of protein-containing complex assembly	biological_process	Any process that modulates the frequency, rate or extent of protein complex assembly.
GO:0043255	regulation of carbohydrate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.
GO:0043256	laminin complex	cellular_component	A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.
GO:0043257	laminin-8 complex	cellular_component	A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.
GO:0043258	laminin-9 complex	cellular_component	A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.
GO:0043259	laminin-10 complex	cellular_component	A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.
GO:0043260	laminin-11 complex	cellular_component	A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.
GO:0043261	laminin-12 complex	cellular_component	A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.
GO:0043262	ADP phosphatase activity	molecular_function	Catalysis of the reaction: ADP + H2O = AMP + phosphate.
GO:0043263	cellulosome	cellular_component	An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose.
GO:0043264	extracellular non-membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.
GO:0043265	ectoplasm	cellular_component	Granule free cytoplasm, lying immediately below the plasma membrane.
GO:0043266	regulation of potassium ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043267	negative regulation of potassium ion transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043268	positive regulation of potassium ion transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043269	regulation of monoatomic ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043270	positive regulation of monoatomic ion transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043271	negative regulation of monoatomic ion transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0043272	ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance	biological_process	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance.
GO:0043273	CTPase activity	molecular_function	Catalysis of the reaction: CTP + H2O = CDP + H+ + phosphate. May or may not be coupled to another reaction.
GO:0043274	phospholipase binding	molecular_function	Binding to a phospholipase.
GO:0043276	anoikis	biological_process	Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.
GO:0043277	apoptotic cell clearance	biological_process	The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
GO:0043278	response to morphine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
GO:0043279	response to alkaloid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	biological_process	Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	biological_process	Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.
GO:0043282	pharyngeal muscle development	biological_process	The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.
GO:0043286	regulation of poly(3-hydroxyalkanoate) biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
GO:0043287	poly(3-hydroxyalkanoate) binding	molecular_function	Binding to a poly(3-hydroxyalkanoate), a polyester of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
GO:0043288	apocarotenoid metabolic process	biological_process	The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
GO:0043289	apocarotenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.
GO:0043290	apocarotenoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
GO:0043291	RAVE complex	cellular_component	A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.
GO:0043292	contractile fiber	cellular_component	Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
GO:0043293	apoptosome	cellular_component	A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
GO:0043294	mitochondrial glutamate synthase complex (NADH)	cellular_component	A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.
GO:0043295	glutathione binding	molecular_function	Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
GO:0043296	apical junction complex	cellular_component	A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
GO:0043297	apical junction assembly	biological_process	The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.
GO:0043299	leukocyte degranulation	biological_process	The regulated exocytosis of secretory granules by a leukocyte.
GO:0043300	regulation of leukocyte degranulation	biological_process	Any process that modulates the frequency, rate, or extent of leukocyte degranulation.
GO:0043301	negative regulation of leukocyte degranulation	biological_process	Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
GO:0043302	positive regulation of leukocyte degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.
GO:0043303	mast cell degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
GO:0043304	regulation of mast cell degranulation	biological_process	Any process that modulates the frequency, rate, or extent of mast cell degranulation.
GO:0043305	negative regulation of mast cell degranulation	biological_process	Any process that stops, prevents, or reduces the rate of mast cell degranulation.
GO:0043306	positive regulation of mast cell degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
GO:0043307	eosinophil activation	biological_process	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0043308	eosinophil degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.
GO:0043309	regulation of eosinophil degranulation	biological_process	Any process that modulates the frequency, rate, or extent of eosinophil degranulation.
GO:0043310	negative regulation of eosinophil degranulation	biological_process	Any process that stops, prevents, or reduces the rate of eosinophil degranulation.
GO:0043311	positive regulation of eosinophil degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.
GO:0043312	neutrophil degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
GO:0043313	regulation of neutrophil degranulation	biological_process	Any process that modulates the frequency, rate, or extent of neutrophil degranulation.
GO:0043314	negative regulation of neutrophil degranulation	biological_process	Any process that stops, prevents, or reduces the rate of neutrophil degranulation.
GO:0043315	positive regulation of neutrophil degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.
GO:0043316	cytotoxic T cell degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
GO:0043317	regulation of cytotoxic T cell degranulation	biological_process	Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.
GO:0043318	negative regulation of cytotoxic T cell degranulation	biological_process	Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation.
GO:0043319	positive regulation of cytotoxic T cell degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.
GO:0043320	natural killer cell degranulation	biological_process	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
GO:0043321	regulation of natural killer cell degranulation	biological_process	Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.
GO:0043322	negative regulation of natural killer cell degranulation	biological_process	Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.
GO:0043323	positive regulation of natural killer cell degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.
GO:0043324	pigment metabolic process involved in developmental pigmentation	biological_process	The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	molecular_function	Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.
GO:0043326	chemotaxis to folate	biological_process	The directed movement of a motile cell or organism in response to the presence of folate.
GO:0043327	chemotaxis to cAMP	biological_process	The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
GO:0043328	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	biological_process	The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.
GO:0043330	response to exogenous dsRNA	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
GO:0043331	response to dsRNA	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
GO:0043332	mating projection tip	cellular_component	The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
GO:0043333	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity	molecular_function	Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0043334	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0043335	protein unfolding	biological_process	The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.
GO:0043336	site-specific telomere resolvase activity	molecular_function	Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.
GO:0043337	cardiolipin synthase (CMP-forming)	molecular_function	Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.
GO:0043338	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity	molecular_function	Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol.
GO:0043353	enucleate erythrocyte differentiation	biological_process	The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.
GO:0043354	enucleate erythrocyte maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.
GO:0043362	nucleate erythrocyte maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.
GO:0043363	nucleate erythrocyte differentiation	biological_process	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.
GO:0043364	glycyl-radical enzyme activating activity	molecular_function	Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).
GO:0043365	[formate-C-acetyltransferase]-activating enzyme activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.
GO:0043366	beta selection	biological_process	The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.
GO:0043367	CD4-positive, alpha-beta T cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
GO:0043368	positive T cell selection	biological_process	The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	biological_process	The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	biological_process	Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	biological_process	The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.
GO:0043374	CD8-positive, alpha-beta T cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	biological_process	The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.
GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	biological_process	Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.
GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	biological_process	Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.
GO:0043379	memory T cell differentiation	biological_process	The process in which a newly activated T cell acquires specialized features of a memory T cell.
GO:0043380	regulation of memory T cell differentiation	biological_process	Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
GO:0043381	negative regulation of memory T cell differentiation	biological_process	Any process that stops, prevents, or reduces the rate of memory T cell differentiation.
GO:0043382	positive regulation of memory T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.
GO:0043383	negative T cell selection	biological_process	The process of elimination of immature T cells which react strongly with self-antigens.
GO:0043384	pre-T cell receptor complex	cellular_component	A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.
GO:0043385	mycotoxin metabolic process	biological_process	The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
GO:0043386	mycotoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
GO:0043387	mycotoxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.
GO:0043388	positive regulation of DNA binding	biological_process	Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO:0043392	negative regulation of DNA binding	biological_process	Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO:0043393	regulation of protein binding	biological_process	Any process that modulates the frequency, rate or extent of protein binding.
GO:0043394	proteoglycan binding	molecular_function	Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:0043395	heparan sulfate proteoglycan binding	molecular_function	Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
GO:0043396	corticotropin-releasing hormone secretion	biological_process	The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.
GO:0043397	regulation of corticotropin-releasing hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.
GO:0043398	HLH domain binding	molecular_function	Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.
GO:0043399	tRNA A64-2'-O-ribosylphosphate transferase activity	molecular_function	Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.
GO:0043400	cortisol secretion	biological_process	The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.
GO:0043401	steroid hormone mediated signaling pathway	biological_process	The series of molecular signals mediated by a steroid hormone binding to a receptor.
GO:0043402	glucocorticoid mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of a glucocorticoid hormone.
GO:0043403	skeletal muscle tissue regeneration	biological_process	The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
GO:0043404	corticotropin-releasing hormone receptor activity	molecular_function	Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.
GO:0043405	regulation of MAP kinase activity	biological_process	Any process that modulates the frequency, rate or extent of MAP kinase activity.
GO:0043406	positive regulation of MAP kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
GO:0043407	negative regulation of MAP kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
GO:0043408	regulation of MAPK cascade	biological_process	Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
GO:0043409	negative regulation of MAPK cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
GO:0043410	positive regulation of MAPK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
GO:0043412	macromolecule modification	biological_process	The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0043413	macromolecule glycosylation	biological_process	The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
GO:0043414	macromolecule methylation	biological_process	The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
GO:0043415	positive regulation of skeletal muscle tissue regeneration	biological_process	Any process that activates or increase the rate of skeletal muscle regeneration.
GO:0043416	regulation of skeletal muscle tissue regeneration	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle.
GO:0043417	negative regulation of skeletal muscle tissue regeneration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.
GO:0043418	homocysteine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.
GO:0043419	urea catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
GO:0043420	anthranilate metabolic process	biological_process	The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
GO:0043421	anthranilate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).
GO:0043422	protein kinase B binding	molecular_function	Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
GO:0043423	3-phosphoinositide-dependent protein kinase binding	molecular_function	Binding to a 3-phosphoinositide-dependent protein kinase.
GO:0043424	protein histidine kinase binding	molecular_function	Binding to a protein histidine kinase.
GO:0043425	bHLH transcription factor binding	molecular_function	Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
GO:0043426	MRF binding	molecular_function	Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
GO:0043427	carbon fixation by 3-hydroxypropionate cycle	biological_process	An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.
GO:0043428	2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0043429	2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0043430	2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
GO:0043431	2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine.
GO:0043433	negative regulation of DNA-binding transcription factor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GO:0043434	response to peptide hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
GO:0043435	response to corticotropin-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
GO:0043436	oxoacid metabolic process	biological_process	The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
GO:0043438	acetoacetic acid metabolic process	biological_process	The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.
GO:0043441	acetoacetic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
GO:0043442	acetoacetic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
GO:0043446	cellular alkane metabolic process	biological_process	The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.
GO:0043447	alkane biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
GO:0043448	alkane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
GO:0043449	cellular alkene metabolic process	biological_process	The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.
GO:0043450	alkene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
GO:0043451	alkene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
GO:0043452	cellular alkyne metabolic process	biological_process	The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.
GO:0043453	alkyne biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.
GO:0043454	alkyne catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.
GO:0043455	regulation of secondary metabolic process	biological_process	Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GO:0043456	regulation of pentose-phosphate shunt	biological_process	Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.
GO:0043457	regulation of cellular respiration	biological_process	Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
GO:0043461	proton-transporting ATP synthase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.
GO:0043462	regulation of ATP-dependent activity	biological_process	Any process that modulates the rate of an ATP-dependent activity.
GO:0043463	regulation of rhamnose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
GO:0043464	malolactic fermentation	biological_process	The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP.
GO:0043465	regulation of fermentation	biological_process	Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).
GO:0043466	pyrimidine nucleobase fermentation	biological_process	The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP.
GO:0043467	regulation of generation of precursor metabolites and energy	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.
GO:0043468	regulation of fucose catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.
GO:0043469	regulation of D-xylose catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.
GO:0043470	regulation of carbohydrate catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.
GO:0043472	IgD binding	molecular_function	Binding to an immunoglobulin of a D isotype.
GO:0043473	pigmentation	biological_process	The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
GO:0043474	pigment metabolic process involved in pigmentation	biological_process	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.
GO:0043475	pigment metabolic process involved in pigment accumulation	biological_process	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.
GO:0043476	pigment accumulation	biological_process	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.
GO:0043477	pigment biosynthetic process involved in pigment accumulation	biological_process	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.
GO:0043478	pigment accumulation in response to UV light	biological_process	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.
GO:0043479	pigment accumulation in tissues in response to UV light	biological_process	The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.
GO:0043480	pigment accumulation in tissues	biological_process	The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.
GO:0043481	anthocyanin accumulation in tissues in response to UV light	biological_process	The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.
GO:0043482	cellular pigment accumulation	biological_process	The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.
GO:0043483	anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light	biological_process	The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.
GO:0043484	regulation of RNA splicing	biological_process	Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
GO:0043485	endosome to pigment granule transport	biological_process	The directed movement of substances from endosomes to pigment granules.
GO:0043487	regulation of RNA stability	biological_process	Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.
GO:0043488	regulation of mRNA stability	biological_process	Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
GO:0043489	RNA stabilization	biological_process	Prevention of degradation of RNA molecules.
GO:0043490	malate-aspartate shuttle	biological_process	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological_process	An intracellular signal transduction pathway that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
GO:0043493	viral terminase complex	cellular_component	A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.
GO:0043494	CLRC complex	cellular_component	An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.
GO:0043495	protein-membrane adaptor activity	molecular_function	The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
GO:0043496	regulation of protein homodimerization activity	biological_process	Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
GO:0043497	regulation of protein heterodimerization activity	biological_process	Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
GO:0043500	muscle adaptation	biological_process	A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
GO:0043501	skeletal muscle adaptation	biological_process	Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
GO:0043502	regulation of muscle adaptation	biological_process	Any process that modulates the frequency, rate or extent of muscle adaptation.
GO:0043503	skeletal muscle fiber adaptation	biological_process	Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
GO:0043504	mitochondrial DNA repair	biological_process	The process of restoring mitochondrial DNA after damage.
GO:0043505	CENP-A containing nucleosome	cellular_component	A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
GO:0043506	regulation of JUN kinase activity	biological_process	Any process that modulates the frequency, rate or extent of JUN kinase activity.
GO:0043507	positive regulation of JUN kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
GO:0043508	negative regulation of JUN kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
GO:0043509	activin A complex	cellular_component	A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
GO:0043510	activin B complex	cellular_component	A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B).
GO:0043511	inhibin complex	cellular_component	Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B.
GO:0043512	inhibin A complex	cellular_component	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.
GO:0043513	inhibin B complex	cellular_component	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
GO:0043514	interleukin-12 complex	cellular_component	A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.
GO:0043515	kinetochore binding	molecular_function	Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	biological_process	Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	biological_process	Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
GO:0043519	regulation of myosin II filament organization	biological_process	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
GO:0043520	regulation of myosin II filament assembly	biological_process	Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.
GO:0043521	regulation of myosin II filament disassembly	biological_process	Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.
GO:0043522	leucine zipper domain binding	molecular_function	Binding to a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.
GO:0043523	regulation of neuron apoptotic process	biological_process	Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
GO:0043524	negative regulation of neuron apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
GO:0043525	positive regulation of neuron apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
GO:0043527	tRNA methyltransferase complex	cellular_component	A multimeric protein complex involved in the methylation of specific nucleotides in tRNA.
GO:0043528	tRNA (m2G10) methyltransferase complex	cellular_component	A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.
GO:0043529	GET complex	cellular_component	An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins.
GO:0043530	adenosine 5'-monophosphoramidase activity	molecular_function	Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.
GO:0043531	ADP binding	molecular_function	Binding to ADP, adenosine 5'-diphosphate.
GO:0043532	angiostatin binding	molecular_function	Binding to angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.
GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding	molecular_function	Binding to inositol 1,3,4,5 tetrakisphosphate.
GO:0043534	blood vessel endothelial cell migration	biological_process	The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
GO:0043535	regulation of blood vessel endothelial cell migration	biological_process	Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
GO:0043536	positive regulation of blood vessel endothelial cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
GO:0043537	negative regulation of blood vessel endothelial cell migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
GO:0043538	regulation of actin phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule.
GO:0043539	protein serine/threonine kinase activator activity	molecular_function	Binds to and increases the activity of a protein serine/threonine kinase.
GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	cellular_component	A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.
GO:0043541	UDP-N-acetylglucosamine transferase complex	cellular_component	A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis.
GO:0043542	endothelial cell migration	biological_process	The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
GO:0043543	protein acylation	biological_process	The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.
GO:0043544	lipoamide binding	molecular_function	Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.
GO:0043545	molybdopterin cofactor metabolic process	biological_process	The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
GO:0043546	molybdopterin cofactor binding	molecular_function	Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
GO:0043547	positive regulation of GTPase activity	biological_process	Any process that activates or increases the activity of a GTPase.
GO:0043548	phosphatidylinositol 3-kinase binding	molecular_function	Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
GO:0043549	regulation of kinase activity	biological_process	Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0043550	regulation of lipid kinase activity	biological_process	Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
GO:0043554	aerobic respiration, using arsenite as electron donor	biological_process	The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems.
GO:0043555	regulation of translation in response to stress	biological_process	Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0043556	regulation of translation in response to oxidative stress	biological_process	Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0043557	regulation of translation in response to osmotic stress	biological_process	Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0043558	regulation of translational initiation in response to stress	biological_process	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.
GO:0043559	insulin binding	molecular_function	Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
GO:0043560	insulin receptor substrate binding	molecular_function	Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
GO:0043561	regulation of translational initiation in response to osmotic stress	biological_process	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0043562	cellular response to nitrogen levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.
GO:0043564	Ku70:Ku80 complex	cellular_component	Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
GO:0043565	sequence-specific DNA binding	molecular_function	Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	biological_process	Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.
GO:0043570	maintenance of DNA repeat elements	biological_process	Any process involved in sustaining the fidelity and copy number of DNA repeat elements.
GO:0043571	maintenance of CRISPR repeat elements	biological_process	Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences.
GO:0043572	plastid fission	biological_process	The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.
GO:0043573	leucoplast fission	biological_process	The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.
GO:0043574	peroxisomal transport	biological_process	Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GO:0043575	detection of osmotic stimulus	biological_process	The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.
GO:0043576	regulation of respiratory gaseous exchange	biological_process	Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.
GO:0043577	chemotropism	biological_process	The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.
GO:0043578	nuclear matrix organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.
GO:0043579	elaioplast organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.
GO:0043580	periplasmic space organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.
GO:0043582	sporangium development	biological_process	The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.
GO:0043583	ear development	biological_process	The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
GO:0043584	nose development	biological_process	The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
GO:0043585	nose morphogenesis	biological_process	The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
GO:0043586	tongue development	biological_process	The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
GO:0043587	tongue morphogenesis	biological_process	The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
GO:0043588	skin development	biological_process	The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
GO:0043589	skin morphogenesis	biological_process	The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
GO:0043590	bacterial nucleoid	cellular_component	The region of a bacterial cell to which the DNA is confined.
GO:0043591	endospore external encapsulating structure	cellular_component	The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.
GO:0043592	exosporium	cellular_component	The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.
GO:0043593	endospore coat	cellular_component	The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination.
GO:0043594	outer endospore membrane	cellular_component	The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.
GO:0043595	endospore cortex	cellular_component	A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.
GO:0043596	nuclear replication fork	cellular_component	The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
GO:0043597	cytoplasmic replication fork	cellular_component	The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
GO:0043598	cytoplasmic DNA replication factor C complex	cellular_component	A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species.
GO:0043599	nuclear DNA replication factor C complex	cellular_component	A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.
GO:0043600	cytoplasmic replisome	cellular_component	A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.
GO:0043601	nuclear replisome	cellular_component	A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
GO:0043602	nitrate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.
GO:0043603	amide metabolic process	biological_process	The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
GO:0043604	amide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
GO:0043605	amide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
GO:0043606	formamide metabolic process	biological_process	The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.
GO:0043607	formamide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.
GO:0043608	formamide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid.
GO:0043609	regulation of carbon utilization	biological_process	Any process that modulates the frequency, rate, or extent of carbon utilization.
GO:0043610	regulation of carbohydrate utilization	biological_process	Any process that modulates the frequency, rate or extent of carbohydrate utilization.
GO:0043611	isoprene metabolic process	biological_process	The chemical reactions and pathways involving isoprene, C5H8.
GO:0043612	isoprene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isoprene, C5H8.
GO:0043613	isoprene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8.
GO:0043614	multi-eIF complex	cellular_component	A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.
GO:0043615	astrocyte cell migration	biological_process	The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.
GO:0043616	keratinocyte proliferation	biological_process	The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
GO:0043617	cellular response to sucrose starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose.
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	biological_process	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	biological_process	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0043620	regulation of DNA-templated transcription in response to stress	biological_process	Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0043621	protein self-association	molecular_function	Binding to a domain within the same polypeptide.
GO:0043622	cortical microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
GO:0043625	delta DNA polymerase complex	cellular_component	A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
GO:0043626	PCNA complex	cellular_component	A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation.
GO:0043627	response to estrogen	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
GO:0043628	regulatory ncRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule.
GO:0043632	modification-dependent macromolecule catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.
GO:0043633	polyadenylation-dependent RNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.
GO:0043634	polyadenylation-dependent ncRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
GO:0043635	methylnaphthalene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.
GO:0043636	bisphenol A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.
GO:0043637	puromycin metabolic process	biological_process	The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.
GO:0043638	puromycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.
GO:0043639	benzoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
GO:0043640	benzoate catabolic process via hydroxylation	biological_process	The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.
GO:0043641	novobiocin metabolic process	biological_process	The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
GO:0043642	novobiocin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
GO:0043643	tetracycline metabolic process	biological_process	The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
GO:0043644	tetracycline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
GO:0043645	cephalosporin metabolic process	biological_process	The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.
GO:0043646	cephalosporin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.
GO:0043647	inositol phosphate metabolic process	biological_process	The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0043648	dicarboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
GO:0043649	dicarboxylic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
GO:0043650	dicarboxylic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
GO:0043651	linoleic acid metabolic process	biological_process	The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
GO:0043652	engulfment of apoptotic cell	biological_process	The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
GO:0043653	mitochondrial fragmentation involved in apoptotic process	biological_process	The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
GO:0043654	recognition of apoptotic cell	biological_process	The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.
GO:0043655	host extracellular space	cellular_component	The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
GO:0043656	host intracellular region	cellular_component	That space within the plasma membrane of a host cell.
GO:0043657	host cell	cellular_component	A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.
GO:0043658	host symbiosome	cellular_component	A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.
GO:0043659	symbiosome	cellular_component	A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane).
GO:0043660	bacteroid-containing symbiosome	cellular_component	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants.
GO:0043661	peribacteroid membrane	cellular_component	A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).
GO:0043662	peribacteroid fluid	cellular_component	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome.
GO:0043663	host bacteroid-containing symbiosome	cellular_component	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.
GO:0043664	host peribacteroid membrane	cellular_component	A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).
GO:0043665	host peribacteroid fluid	cellular_component	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell.
GO:0043666	regulation of phosphoprotein phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.
GO:0043667	pollen wall	cellular_component	The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.
GO:0043668	exine	cellular_component	The outer layer of the pollen grain wall which is composed primarily of sporopollenin.
GO:0043669	ectexine	cellular_component	The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections.
GO:0043670	foot layer	cellular_component	The inner layer of the ectexine.
GO:0043671	endexine	cellular_component	The inner part of the exine, which stains.
GO:0043672	nexine	cellular_component	The inner, non-sculptured part of the exine which lies below the sexine.
GO:0043673	sexine	cellular_component	The outer, sculptured layer of the exine, which lies above the nexine.
GO:0043674	columella	cellular_component	A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella).
GO:0043675	sculpture element	cellular_component	The third layer of the sexine.
GO:0043676	tectum	cellular_component	The layer of sexine which forms a roof over the columella, granules or other infratectal elements.
GO:0043678	intine	cellular_component	The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm.
GO:0043679	axon terminus	cellular_component	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
GO:0043680	filiform apparatus	cellular_component	A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells.
GO:0043682	P-type divalent copper transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) = ADP + phosphate + Cu2+(out).
GO:0043683	type IV pilus assembly	biological_process	The assembly from its constituent parts of a type IV pilus.
GO:0043684	type IV secretion system complex	cellular_component	A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s).
GO:0043685	conversion of glutamyl-tRNA to glutaminyl-tRNA	biological_process	The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.
GO:0043686	co-translational protein modification	biological_process	The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.
GO:0043687	post-translational protein modification	biological_process	The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
GO:0043688	conversion of aspartyl-tRNA to asparaginyl-tRNA	biological_process	The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA.
GO:0043691	reverse cholesterol transport	biological_process	The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism.
GO:0043692	monoterpene metabolic process	biological_process	The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.
GO:0043693	monoterpene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.
GO:0043694	monoterpene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.
GO:0043695	detection of pheromone	biological_process	The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.
GO:0043696	dedifferentiation	biological_process	The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.
GO:0043697	cell dedifferentiation	biological_process	The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
GO:0043698	iridosome	cellular_component	A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance.
GO:0043699	leucosome	cellular_component	A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast.
GO:0043700	pterinosome	cellular_component	A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.
GO:0043701	cyanosome	cellular_component	A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance.
GO:0043702	carotenoid vesicle	cellular_component	A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.
GO:0043703	photoreceptor cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0043704	photoreceptor cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0043705	cyanophycin metabolic process	biological_process	The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups.
GO:0043707	cell adhesion involved in single-species biofilm formation in or on host organism	biological_process	The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.
GO:0043708	cell adhesion involved in biofilm formation	biological_process	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.
GO:0043709	cell adhesion involved in single-species biofilm formation	biological_process	The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
GO:0043710	cell adhesion involved in multi-species biofilm formation	biological_process	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.
GO:0043711	pilus organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.
GO:0043712	2-hydroxyisocaproate CoA-transferase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.
GO:0043713	(R)-2-hydroxyisocaproate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+.
GO:0043714	(R)-citramalate synthase activity	molecular_function	Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA.
GO:0043715	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity	molecular_function	Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.
GO:0043716	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.
GO:0043717	2-hydroxyglutaryl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.
GO:0043718	2-hydroxymethylglutarate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD+ = 2-formylglutarate + H+ + NADH.
GO:0043719	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity	molecular_function	Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O.
GO:0043720	3-keto-5-aminohexanoate cleavage activity	molecular_function	Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.
GO:0043721	4-hydroxybutanoyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O.
GO:0043722	4-hydroxyphenylacetate decarboxylase activity	molecular_function	Catalysis of the reaction: (4-hydroxyphenyl)acetate + H+ = 4-cresol + CO2.
GO:0043723	2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity	molecular_function	Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia.
GO:0043724	2-keto-3-deoxygalactonate aldolase activity	molecular_function	Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.
GO:0043726	5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	molecular_function	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate.
GO:0043727	5-amino-4-imidazole carboxylate lyase activity	molecular_function	Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate.
GO:0043728	2-keto-4-methylthiobutyrate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine.
GO:0043729	2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity	molecular_function	Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate + H+.
GO:0043730	5-ureido-4-imidazole carboxylate hydrolase activity	molecular_function	Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2.
GO:0043731	6-hydroxynicotinate 3-monooxygenase activity	molecular_function	Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.
GO:0043732	6-hydroxynicotinate dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2.
GO:0043733	DNA-3-methylbase glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.
GO:0043734	DNA-N1-methyladenine dioxygenase activity	molecular_function	Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde.
GO:0043737	deoxyribonuclease V activity	molecular_function	Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.
GO:0043738	reduced coenzyme F420 dehydrogenase activity	molecular_function	Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.
GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity	molecular_function	Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free uracil and leaving an apyrimidinic (AP) site.
GO:0043740	GTP cyclohydrolase IIa activity	molecular_function	Catalysis of the reaction: GTP + 3 H2O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H+ + 2 phosphate.
GO:0043741	alpha-aminoadipate acetyltransferase activity	molecular_function	Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.
GO:0043743	LPPG:FO 2-phospho-L-lactate transferase activity	molecular_function	Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP.
GO:0043744	N2-acetyl-L-aminoadipate kinase activity	molecular_function	Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate.
GO:0043748	O-succinylbenzoate synthase activity	molecular_function	Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.
GO:0043749	phenol, water dikinase activity	molecular_function	Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate.
GO:0043750	phosphatidylinositol alpha-mannosyltransferase activity	molecular_function	Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.
GO:0043751	polyphosphate:AMP phosphotransferase activity	molecular_function	Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP.
GO:0043752	adenosylcobinamide kinase activity	molecular_function	Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).
GO:0043754	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	molecular_function	Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine.
GO:0043755	alpha-ribazole phosphatase activity	molecular_function	Catalysis of the reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate.
GO:0043756	adenosylcobinamide hydrolase activity	molecular_function	Catalysis of the reaction: adenosylcobinamide + H2O = (R)-1-aminopropan-2-ol + adenosylcobyrate.
GO:0043757	adenosylcobinamide-phosphate synthase activity	molecular_function	Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.
GO:0043758	acetate-CoA ligase (ADP-forming) activity	molecular_function	Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.
GO:0043759	methylbutanoate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP + diphosphate + 2-methylbutanoyl-CoA.
GO:0043760	acetyldiaminopimelate aminotransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate.
GO:0043761	archaetidylserine synthase activity	molecular_function	Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP.
GO:0043763	UTP:glucose-1-phosphate uridylyltransferase regulator activity	molecular_function	Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.
GO:0043765	T/G mismatch-specific endonuclease activity	molecular_function	Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.
GO:0043766	Sep-tRNA:Cys-tRNA synthase activity	molecular_function	Catalysis of the reaction: H+ + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys) = L-cysteinyl-tRNA(Cys) + phosphate.
GO:0043767	pyrrolysyl-tRNA synthetase activity	molecular_function	Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).
GO:0043768	S-ribosylhomocysteine lyase activity	molecular_function	Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.
GO:0043769	Tpg-containing telomere binding complex	cellular_component	A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.
GO:0043770	demethylmenaquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine.
GO:0043771	cytidine kinase activity	molecular_function	Catalysis of the reaction: ATP + cytidine = ADP + CMP.
GO:0043772	acyl-phosphate glycerol-3-phosphate acyltransferase activity	molecular_function	Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.
GO:0043773	coenzyme F420-0 gamma-glutamyl ligase activity	molecular_function	Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.
GO:0043774	coenzyme F420-2 alpha-glutamyl ligase activity	molecular_function	Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate.
GO:0043776	cobalt-precorrin-6B C5-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.
GO:0043777	cobalt-precorrin-7 C15-methyltransferase activity	molecular_function	Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2.
GO:0043778	cobalt-precorrin-8 methylmutase activity	molecular_function	Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.
GO:0043779	cobalt-precorrin-5A acetaldehyde-lyase activity	molecular_function	Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde + H+.
GO:0043780	cobalt-precorrin-5B C1-methyltransferase activity	molecular_function	Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.
GO:0043781	cobalt-factor II C20-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III.
GO:0043782	cobalt-precorrin-3 C17-methyltransferase activity	molecular_function	Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.
GO:0043783	oxidoreductase activity, acting on metal ions, flavin as acceptor	molecular_function	Catalysis of an oxidation-reduction in which the metal ion is reduced and flavin acts as an electron acceptor.
GO:0043785	cinnamoyl-CoA:phenyllactate CoA-transferase activity	molecular_function	Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate.
GO:0043786	cinnamate reductase activity	molecular_function	Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.
GO:0043791	dimethylamine methyltransferase activity	molecular_function	Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.
GO:0043792	enamidase activity	molecular_function	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O = 2-formylglutarate + NH4.
GO:0043793	beta-ribofuranosylaminobenzene 5'-phosphate synthase activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.
GO:0043794	formate dehydrogenase (coenzyme F420) activity	molecular_function	Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.
GO:0043795	glyceraldehyde oxidoreductase activity	molecular_function	Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H+.
GO:0043796	glyceraldehyde dehydrogenase (NADP) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.
GO:0043797	glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin.
GO:0043798	glycerate 2-kinase activity	molecular_function	Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.
GO:0043799	glycine oxidase activity	molecular_function	Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.
GO:0043800	hexulose-6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate.
GO:0043801	hexulose-6-phosphate synthase activity	molecular_function	Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.
GO:0043802	hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity	molecular_function	Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H2O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H+ + hydrogenobyrinate a,c-diamide + 2 phosphate.
GO:0043803	hydroxyneurosporene-O-methyltransferase activity	molecular_function	Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + spheroidene.
GO:0043804	imidazolone hydrolase activity	molecular_function	Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one.
GO:0043805	indolepyruvate ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.
GO:0043806	keto acid formate lyase activity	molecular_function	Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate.
GO:0043807	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	molecular_function	Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.
GO:0043808	lyso-ornithine lipid acyltransferase activity	molecular_function	Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].
GO:0043810	ornithine-acyl [acyl carrier protein] N-acyltransferase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.
GO:0043811	phosphate:acyl-[acyl carrier protein] acyltransferase activity	molecular_function	Catalysis of the reaction: a fatty acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].
GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidyl-1D-myo-inositol-4-phosphate + H2O = phosphatidyl-1D-myo-inositol + phosphate.
GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.
GO:0043814	phospholactate guanylyltransferase activity	molecular_function	Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.
GO:0043815	phosphoribosylglycinamide formyltransferase 2 activity	molecular_function	Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.
GO:0043816	phosphoserine-tRNA(Cys) ligase activity	molecular_function	Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).
GO:0043817	phosphosulfolactate synthase activity	molecular_function	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite.
GO:0043818	precorrin-3B synthase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + precorrin-3A = H2O + NAD+ + precorrin-3B.
GO:0043819	precorrin-6A synthase (deacetylating) activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + H2O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H+ + precorrin-6X.
GO:0043820	propionyl-CoA dehydrogenase activity	molecular_function	Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA.
GO:0043821	propionyl-CoA:succinate CoA-transferase activity	molecular_function	Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.
GO:0043822	ribonuclease M5 activity	molecular_function	Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.
GO:0043823	spheroidene monooxygenase activity	molecular_function	Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.
GO:0043824	succinylglutamate-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H2O + NAD+ = N-succinyl-L-glutamate + 2 H+ + NADH.
GO:0043825	succinylornithine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.
GO:0043826	sulfur oxygenase reductase activity	molecular_function	Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+.
GO:0043827	tRNA (adenine-57, 58-N(1)-) methyltransferase activity	molecular_function	Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA.
GO:0043828	tRNA 2-selenouridine synthase activity	molecular_function	Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).
GO:0043829	tRNA-specific adenosine-37 deaminase activity	molecular_function	Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule.
GO:0043830	thiol-driven fumarate reductase activity	molecular_function	Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.
GO:0043831	thiosulfate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.
GO:0043833	[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase activity	molecular_function	Catalysis of the reaction: [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M = [Co(I) methylamine-specific corrinoid protein] + H+ + methyl-coenzyme M. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.
GO:0043834	trimethylamine methyltransferase activity	molecular_function	Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine.
GO:0043836	xanthine hydrolase activity	molecular_function	Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate.
GO:0043837	valine dehydrogenase (NAD) activity	molecular_function	Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH.
GO:0043838	phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity	molecular_function	Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.
GO:0043839	lipid A phosphate methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.
GO:0043840	branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine.
GO:0043841	(S)-lactate 2-kinase activity	molecular_function	Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP.
GO:0043842	Kdo transferase activity	molecular_function	Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.
GO:0043843	ADP-specific glucokinase activity	molecular_function	Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.
GO:0043844	ADP-specific phosphofructokinase activity	molecular_function	Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.
GO:0043845	DNA polymerase III, proofreading complex	cellular_component	A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.
GO:0043846	DNA polymerase III, clamp loader complex	cellular_component	A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
GO:0043847	DNA polymerase III, clamp loader chi/psi subcomplex	cellular_component	A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB).
GO:0043849	Ras palmitoyltransferase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.
GO:0043850	RecFOR complex	cellular_component	A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair.
GO:0043852	monomethylamine methyltransferase activity	molecular_function	Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.
GO:0043853	methanol-CoM methyltransferase complex	cellular_component	A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol.
GO:0043854	cyclic nucleotide-gated mechanosensitive monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
GO:0043855	cyclic nucleotide-gated monoatomic ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
GO:0043856	anti-sigma factor antagonist activity	molecular_function	The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.
GO:0043857	N-acetylornithine carbamoyltransferase activity	molecular_function	Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H+ + phosphate.
GO:0043858	arginine:ornithine antiporter activity	molecular_function	Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out).
GO:0043860	cyanophycin synthetase activity	molecular_function	Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
GO:0043861	agmatine:putrescine antiporter activity	molecular_function	Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out).
GO:0043862	arginine:agmatine antiporter activity	molecular_function	Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).
GO:0043863	4-hydroxy-2-ketopimelate aldolase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.
GO:0043864	indoleacetamide hydrolase activity	molecular_function	Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.
GO:0043865	methionine transmembrane transporter activity	molecular_function	Enables the transfer of methionine from one side of a membrane to the other.
GO:0043866	adenylyl-sulfate reductase (thioredoxin) activity	molecular_function	Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin.
GO:0043867	7-cyano-7-deazaguanine tRNA-ribosyltransferase activity	molecular_function	Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.
GO:0043870	N-acetyl-gamma-aminoadipyl-phosphate reductase activity	molecular_function	Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH.
GO:0043871	delta1-piperideine-6-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
GO:0043872	lysine:cadaverine antiporter activity	molecular_function	Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out).
GO:0043873	pyruvate-flavodoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
GO:0043874	acireductone synthase activity	molecular_function	Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
GO:0043875	2-ketobutyrate formate-lyase activity	molecular_function	Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.
GO:0043876	D-threonine aldolase activity	molecular_function	Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.
GO:0043877	galactosamine-6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.
GO:0043878	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.
GO:0043879	glycolate transmembrane transporter activity	molecular_function	Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).
GO:0043880	crotonyl-CoA reductase activity	molecular_function	Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.
GO:0043881	mesaconyl-CoA hydratase activity	molecular_function	Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.
GO:0043882	malate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).
GO:0043883	malolactic enzyme activity	molecular_function	Catalysis of the reaction: malate + H+ = L-lactate + CO2.
GO:0043884	CO-methylating acetyl-CoA synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA.
GO:0043885	carbon-monoxide dehydrogenase (ferredoxin) activity	molecular_function	Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.
GO:0043886	structural constituent of carboxysome shell	molecular_function	The action of a molecule that contributes to the structural integrity of a carboxysome shell, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO2.
GO:0043887	melibiose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).
GO:0043888	(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity	molecular_function	Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate.
GO:0043889	(S)-3-O-geranylgeranylglyceryl phosphate synthase activity	molecular_function	Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate.
GO:0043890	N-acetylgalactosamine-6-sulfatase activity	molecular_function	Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.
GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.
GO:0043892	methylglyoxal reductase (NADPH-dependent) activity	molecular_function	Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.
GO:0043893	acetate:monoatomic cation symporter activity	molecular_function	Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).
GO:0043894	acetyl-CoA synthetase acetyltransferase activity	molecular_function	Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate.
GO:0043895	cyclomaltodextrin glucanotransferase activity	molecular_function	Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.
GO:0043896	glucan 1,6-alpha-glucosidase activity	molecular_function	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.
GO:0043897	glucan 1,4-alpha-maltohydrolase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.
GO:0043898	2,3-dihydroxybiphenyl 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.
GO:0043899	phosphoserine:homoserine phosphotransferase activity	molecular_function	Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.
GO:0043903	regulation of biological process involved in symbiotic interaction	biological_process	Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
GO:0043904	isochorismate pyruvate lyase activity	molecular_function	Catalysis of the reaction: isochorismate = salicylate + pyruvate.
GO:0043905	L-seryl-tRNA(Thr) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).
GO:0043906	Ala-tRNA(Pro) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).
GO:0043907	Cys-tRNA(Pro) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro).
GO:0043908	Ser(Gly)-tRNA(Ala) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).
GO:0043909	N-acetylcitrulline deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.
GO:0043910	ATP:coenzyme F420 adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.
GO:0043911	D-lysine transaminase activity	molecular_function	Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate.
GO:0043912	D-lysine oxidase activity	molecular_function	Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.
GO:0043914	NADPH:sulfur oxidoreductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.
GO:0043915	L-seryl-tRNA(Sec) kinase activity	molecular_function	Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
GO:0043916	DNA-7-methylguanine glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.
GO:0043917	ribose 1,5-bisphosphate isomerase activity	molecular_function	Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.
GO:0043918	cadaverine aminopropyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine.
GO:0043919	agmatine aminopropyltransferase activity	molecular_function	Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.
GO:0043920	aminopropylagmatine ureohydrolase activity	molecular_function	Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.
GO:0043921	modulation by host of viral transcription	biological_process	Any process in which a host organism modulates the frequency, rate or extent of viral transcription.
GO:0043922	negative regulation by host of viral transcription	biological_process	Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.
GO:0043923	positive regulation by host of viral transcription	biological_process	Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
GO:0043924	suramin binding	molecular_function	Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.
GO:0043928	exonucleolytic catabolism of deadenylated mRNA	biological_process	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.
GO:0043929	primary ovarian follicle growth involved in double layer follicle stage	biological_process	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.
GO:0043930	primary ovarian follicle growth involved in primary follicle stage	biological_process	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis.
GO:0043931	ossification involved in bone maturation	biological_process	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
GO:0043932	ossification involved in bone remodeling	biological_process	The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
GO:0043933	protein-containing complex organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
GO:0043934	sporulation	biological_process	The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
GO:0043935	sexual sporulation resulting in formation of a cellular spore	biological_process	The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
GO:0043936	asexual sporulation resulting in formation of a cellular spore	biological_process	The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
GO:0043937	regulation of sporulation	biological_process	Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
GO:0043938	positive regulation of sporulation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
GO:0043939	negative regulation of sporulation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
GO:0043940	regulation of sexual sporulation resulting in formation of a cellular spore	biological_process	Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
GO:0043941	positive regulation of sexual sporulation resulting in formation of a cellular spore	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
GO:0043942	negative regulation of sexual sporulation resulting in formation of a cellular spore	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
GO:0043943	regulation of asexual sporulation resulting in formation of a cellular spore	biological_process	Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
GO:0043944	negative regulation of asexual sporulation resulting in formation of a cellular spore	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
GO:0043945	positive regulation of asexual sporulation resulting in formation of a cellular spore	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
GO:0043949	regulation of cAMP-mediated signaling	biological_process	Any process which modulates the frequency, rate or extent of cAMP-mediated signaling.
GO:0043950	positive regulation of cAMP-mediated signaling	biological_process	Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling.
GO:0043951	negative regulation of cAMP-mediated signaling	biological_process	Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling.
GO:0043952	protein transport by the Sec complex	biological_process	The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
GO:0043953	protein transport by the Tat complex	biological_process	The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.
GO:0043954	cellular component maintenance	biological_process	The organization process that preserves a cellular component in a stable functional or structural state.
GO:0043955	3-hydroxypropionyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.
GO:0043956	3-hydroxypropionyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: 3-hydroxypropionyl-CoA = acryloyl-CoA + H2O.
GO:0043957	acryloyl-CoA reductase (NADP+) activity	molecular_function	Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.
GO:0043958	acryloyl-CoA reductase (NADH) activity	molecular_function	Catalysis of the reaction: propanoyl-CoA + NAD+ = acryloyl-CoA + H+ + NADH.
GO:0043959	L-erythro-3-methylmalyl-CoA lyase activity	molecular_function	Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA.
GO:0043960	L-erythro-3-methylmalyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O.
GO:0043961	succinyl-CoA:(R)-citramalate CoA-transferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.
GO:0043963	perturbation of host adenylate cyclase-mediated signal transduction	biological_process	A process in which a symbiont alters or subverts an adenylate cyclase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0043965	symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction	biological_process	A process in which a virus interferes with, inhibits or disrupts an adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0043966	histone H3 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group.
GO:0043967	histone H4 acetylation	biological_process	The modification of histone H4 by the addition of an acetyl group.
GO:0043968	histone H2A acetylation	biological_process	The modification of histone H2A by the addition of an acetyl group.
GO:0043969	histone H2B acetylation	biological_process	The modification of histone H2B by the addition of an acetyl group.
GO:0043970	histone H3-K9 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.
GO:0043971	histone H3-K18 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.
GO:0043972	histone H3-K23 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone.
GO:0043973	histone H3-K4 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.
GO:0043974	histone H3-K27 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone.
GO:0043977	histone H2A-K5 acetylation	biological_process	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone.
GO:0043979	histone H2B-K5 acetylation	biological_process	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.
GO:0043980	histone H2B-K12 acetylation	biological_process	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone.
GO:0043981	histone H4-K5 acetylation	biological_process	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
GO:0043982	histone H4-K8 acetylation	biological_process	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
GO:0043983	histone H4-K12 acetylation	biological_process	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
GO:0043984	histone H4-K16 acetylation	biological_process	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.
GO:0043985	histone H4-R3 methylation	biological_process	The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone.
GO:0043992	histone H3K9 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).
GO:0043993	histone H3K18 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).
GO:0043994	histone H3K23 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).
GO:0043995	histone H4K5 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).
GO:0043996	histone H4K8 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).
GO:0043997	histone H4K12 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).
GO:0043998	histone H2A acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
GO:0043999	histone H2AK5 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).
GO:0044000	movement in host	biological_process	The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044001	migration in host	biological_process	The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044002	acquisition of nutrients from host	biological_process	The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044003	modulation by symbiont of host process	biological_process	The process in which a symbiont organism effects a change in the structure or processes of its host organism.
GO:0044010	single-species biofilm formation	biological_process	A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0044011	single-species biofilm formation on inanimate substrate	biological_process	A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
GO:0044012	histone H2AK9 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).
GO:0044013	histone H2B acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.
GO:0044014	histone H2BK5 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).
GO:0044015	histone H2BK12 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12).
GO:0044016	histone H3K4 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).
GO:0044017	histone H3K27 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).
GO:0044018	histone H3K36 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).
GO:0044019	histone H3K72 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).
GO:0044020	histone H4R3 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H4, producing histone H4R3me.
GO:0044022	histone H3S28 kinase activity	molecular_function	Catalysis of the reaction: histone H3-serine (position 28) + ATP = histone H3-phosphoserine (position 28) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 28 of histone H3.
GO:0044023	histone H4S1 kinase activity	molecular_function	Catalysis of the reaction: histone H4-serine (position 1) + ATP = histone H4-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H4.
GO:0044024	histone H2AS1 kinase activity	molecular_function	Catalysis of the reaction: histone H2A-serine (position 1) + ATP = histone H2A-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H2A.
GO:0044025	histone H2BS14 kinase activity	molecular_function	Catalysis of the reaction: histone H2B-serine (position 14) + ATP = histone H2B-phosphoserine (position 14) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 14 of histone H2B.
GO:0044027	negative regulation of gene expression via CpG island methylation	biological_process	An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.
GO:0044029	positive regulation of gene expression via CpG island demethylation	biological_process	An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.
GO:0044030	regulation of DNA methylation	biological_process	Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
GO:0044032	modulation by symbiont of indole acetic acid levels in host	biological_process	The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044036	cell wall macromolecule metabolic process	biological_process	The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0044038	cell wall macromolecule biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.
GO:0044042	glucan metabolic process	biological_process	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.
GO:0044053	translocation of peptides or proteins into host cell cytoplasm	biological_process	The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm.
GO:0044057	regulation of system process	biological_process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
GO:0044058	regulation of digestive system process	biological_process	Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0044060	regulation of endocrine process	biological_process	Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
GO:0044062	regulation of excretion	biological_process	Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.
GO:0044065	regulation of respiratory system process	biological_process	Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.
GO:0044066	disruption by symbiont of host cell nucleus	biological_process	The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus.
GO:0044067	disruption of host cell-cell junction	biological_process	The process by which a symbiont effects a change in the structure or function of an intercellular junction of the host. Intercellular junction include tight junctions and adherens junctions.
GO:0044068	modulation by symbiont of host cellular process	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.
GO:0044069	modulation by symbiont of host anion transport	biological_process	The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.
GO:0044070	regulation of monoatomic anion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0044071	perturbation of host cell cycle progression	biological_process	A process in which a symbiont interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044072	suppression of host cell cycle progression	biological_process	A process in which a symbiont interferes with, inhibits or stops progression through the host cell cycle.
GO:0044073	modulation by symbiont of host translation	biological_process	The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.
GO:0044074	negative regulation by symbiont of host translation	biological_process	The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.
GO:0044075	modulation by symbiont of host vacuole organization	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism.
GO:0044076	positive regulation by symbiont of host vacuole organization	biological_process	The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism.
GO:0044077	modulation by symbiont of host receptor-mediated endocytosis	biological_process	The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.
GO:0044078	positive regulation by symbiont of host receptor-mediated endocytosis	biological_process	Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.
GO:0044079	modulation by symbiont of host neurotransmitter secretion	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism.
GO:0044080	perturbation of host cGMP-mediated signal transduction	biological_process	A process in which a symbiont alters or subverts a cGMP-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044081	symbiont-mediated suppression of host nitric oxide-mediated signaling	biological_process	A process in which a virus interferes with, inhibits or disrupts a nitric oxide mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044082	perturbation of host small GTPase mediated signal transduction	biological_process	A process in which a symbiont alters or subverts a small GTPase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044083	perturbation of host Rho protein signal transduction	biological_process	A process in which a symbiont alters a Rho protein family-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044084	host cell membrane pore complex	cellular_component	Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins.
GO:0044085	cellular component biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GO:0044087	regulation of cellular component biogenesis	biological_process	Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GO:0044088	regulation of vacuole organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GO:0044089	positive regulation of cellular component biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GO:0044090	positive regulation of vacuole organization	biological_process	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GO:0044091	membrane biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
GO:0044092	negative regulation of molecular function	biological_process	Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0044093	positive regulation of molecular function	biological_process	Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0044094	host cell nuclear part	cellular_component	Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.
GO:0044095	host cell nucleoplasm	cellular_component	That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.
GO:0044096	type IV pilus	cellular_component	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers.
GO:0044097	secretion by the type IV secretion system	biological_process	The controlled release of proteins or DNA by a cell, via the type IV secretion system.
GO:0044098	DNA secretion by the type IV secretion system	biological_process	The controlled release of DNA by a cell, via the type IV secretion system.
GO:0044099	polar tube	cellular_component	A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell.
GO:0044100	sporoplasm	cellular_component	The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms.
GO:0044101	(R)-citramalyl-CoA lyase activity	molecular_function	Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA.
GO:0044102	purine deoxyribosyltransferase activity	molecular_function	Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor.
GO:0044103	L-arabinose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.
GO:0044104	2,5-dioxovalerate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+.
GO:0044105	L-xylulose reductase (NAD+) activity	molecular_function	Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.
GO:0044111	formation of structure involved in a symbiotic process	biological_process	The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
GO:0044114	development of symbiont in host	biological_process	The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044127	regulation of development of symbiont in host	biological_process	Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.
GO:0044129	positive regulation of development of symbiont in host	biological_process	Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
GO:0044131	negative regulation of development of symbiont in host	biological_process	Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
GO:0044145	modulation of formation of structure involved in a symbiotic process	biological_process	Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
GO:0044147	negative regulation of formation of structure involved in a symbiotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
GO:0044149	positive regulation of formation of structure involved in a symbiotic process	biological_process	Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
GO:0044154	histone H3-K14 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone.
GO:0044155	host caveola	cellular_component	A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044156	host cell junction	cellular_component	A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
GO:0044157	host cell projection	cellular_component	A prolongation or process extending from a host cell, e.g. a flagellum or axon.
GO:0044158	host cell wall	cellular_component	The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO:0044159	host thylakoid	cellular_component	A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
GO:0044160	host thylakoid membrane	cellular_component	The pigmented membrane of any host thylakoid.
GO:0044161	host cell cytoplasmic vesicle	cellular_component	A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.
GO:0044162	host cell cytoplasmic vesicle membrane	cellular_component	The lipid bilayer surrounding a host cell cytoplasmic vesicle.
GO:0044163	host cytoskeleton	cellular_component	A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GO:0044164	host cell cytosol	cellular_component	The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0044165	host cell endoplasmic reticulum	cellular_component	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
GO:0044166	host cell endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the host cell endoplasmic reticulum.
GO:0044167	host cell endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the host cell endoplasmic reticulum.
GO:0044168	host cell rough endoplasmic reticulum	cellular_component	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.
GO:0044169	host cell rough endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the host cell rough endoplasmic reticulum.
GO:0044170	host cell smooth endoplasmic reticulum	cellular_component	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface.
GO:0044171	host cell smooth endoplasmic reticulum membrane	cellular_component	The lipid bilayer surrounding the host cell smooth endoplasmic reticulum.
GO:0044172	host cell endoplasmic reticulum-Golgi intermediate compartment	cellular_component	A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.
GO:0044173	host cell endoplasmic reticulum-Golgi intermediate compartment membrane	cellular_component	The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system.
GO:0044174	host cell endosome	cellular_component	A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
GO:0044175	host cell endosome membrane	cellular_component	The lipid bilayer surrounding a host cell endosome.
GO:0044176	host cell filopodium	cellular_component	Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
GO:0044177	host cell Golgi apparatus	cellular_component	A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
GO:0044178	host cell Golgi membrane	cellular_component	The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.
GO:0044179	hemolysis in another organism	biological_process	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.
GO:0044180	filamentous growth of a unicellular organism	biological_process	The process in which a unicellular organism grows in a threadlike, filamentous shape.
GO:0044181	filamentous growth of a multicellular organism	biological_process	The process in which a multicellular organism grows in a threadlike, filamentous shape.
GO:0044182	filamentous growth of a population of unicellular organisms	biological_process	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
GO:0044183	protein folding chaperone	molecular_function	Binding to a protein or a protein-containing complex to assist the protein folding process.
GO:0044184	host cell late endosome	cellular_component	A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
GO:0044185	host cell late endosome membrane	cellular_component	The lipid bilayer surrounding a host cell late endosome.
GO:0044186	host cell lipid droplet	cellular_component	Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins.
GO:0044187	host cell lysosome	cellular_component	A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.
GO:0044188	host cell lysosomal membrane	cellular_component	The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm.
GO:0044190	host cell mitochondrial envelope	cellular_component	The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.
GO:0044191	host cell mitochondrial membrane	cellular_component	Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.
GO:0044192	host cell mitochondrial inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.
GO:0044193	host cell mitochondrial outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope.
GO:0044194	cytolytic granule	cellular_component	A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.
GO:0044195	nucleoplasmic reticulum	cellular_component	Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.
GO:0044196	host cell nucleolus	cellular_component	A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.
GO:0044197	Rel homology domain binding	molecular_function	Binding to a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT.
GO:0044198	zf-TRAF domain binding	molecular_function	Binding to a TRAF-type zinc finger domain of a protein.
GO:0044199	host cell nuclear envelope	cellular_component	The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
GO:0044200	host cell nuclear membrane	cellular_component	Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.
GO:0044201	host cell nuclear inner membrane	cellular_component	The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.
GO:0044202	host cell nuclear outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.
GO:0044203	host cell nuclear lamina	cellular_component	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.
GO:0044204	host cell nuclear matrix	cellular_component	The dense fibrillar network lying on the inner side of the host nuclear membrane.
GO:0044205	'de novo' UMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.
GO:0044206	UMP salvage	biological_process	Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.
GO:0044207	translation initiation ternary complex	cellular_component	A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
GO:0044208	'de novo' AMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).
GO:0044209	AMP salvage	biological_process	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.
GO:0044210	'de novo' CTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
GO:0044211	CTP salvage	biological_process	Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.
GO:0044217	other organism part	cellular_component	Any constituent part of a secondary organism with which the first organism is interacting.
GO:0044218	other organism cell membrane	cellular_component	The cell membrane of a secondary organism with which the first organism is interacting.
GO:0044219	host cell plasmodesma	cellular_component	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.
GO:0044220	host cell perinuclear region of cytoplasm	cellular_component	The host cell cytoplasm situated near, or occurring around, the host nucleus.
GO:0044221	host cell synapse	cellular_component	The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.
GO:0044222	anammoxosome	cellular_component	An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.
GO:0044223	pirellulosome	cellular_component	A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.
GO:0044224	juxtaparanode region of axon	cellular_component	A region of an axon near a node of Ranvier that is between the paranode and internode regions.
GO:0044225	apical pole of neuron	cellular_component	Portion of a neuron cell soma closest to the point where the apical dendrite emerges.
GO:0044226	basal pole of neuron	cellular_component	Portion of a neuron cell soma closest to the point where the basilar dendrite emerges.
GO:0044227	methane-oxidizing organelle	cellular_component	A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.
GO:0044228	host cell surface	cellular_component	The external part of the host cell wall and/or host plasma membrane.
GO:0044229	host cell periplasmic space	cellular_component	The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).
GO:0044230	host cell envelope	cellular_component	An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.
GO:0044231	host cell presynaptic membrane	cellular_component	A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
GO:0044232	organelle membrane contact site	cellular_component	A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
GO:0044233	mitochondria-associated endoplasmic reticulum membrane	cellular_component	A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
GO:0044237	cellular metabolic process	biological_process	The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0044238	primary metabolic process	biological_process	The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044241	lipid digestion	biological_process	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
GO:0044242	cellular lipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
GO:0044245	polysaccharide digestion	biological_process	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
GO:0044248	cellular catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GO:0044249	cellular biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0044250	negative regulation of metabolic activity involved in hibernation	biological_process	The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.
GO:0044255	cellular lipid metabolic process	biological_process	The chemical reactions and pathways involving lipids, as carried out by individual cells.
GO:0044256	protein digestion	biological_process	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.
GO:0044258	intestinal lipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.
GO:0044269	glycerol ether catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
GO:0044270	cellular nitrogen compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.
GO:0044271	cellular nitrogen compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
GO:0044272	sulfur compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0044273	sulfur compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0044277	cell wall disassembly	biological_process	A process that results in the breakdown of the cell wall.
GO:0044278	disruption of cell wall in another organism	biological_process	The disruption of the cell wall of another organism, leading to damage or temporary subversion of the cell wall.
GO:0044280	subplasmalemmal coating	cellular_component	Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.
GO:0044281	small molecule metabolic process	biological_process	The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0044282	small molecule catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0044283	small molecule biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0044284	mitochondrial crista junction	cellular_component	A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.
GO:0044286	peg and socket contact	cellular_component	A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.
GO:0044288	puncta adhaerentia	cellular_component	A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.
GO:0044289	mitochondrial inner-outer membrane contact site	cellular_component	Sites of close apposition of the inner and outer mitochondrial membrane.
GO:0044290	mitochondrial intracristal space	cellular_component	The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.
GO:0044291	cell-cell contact zone	cellular_component	Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
GO:0044292	dendrite terminus	cellular_component	A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.
GO:0044293	dendriole	cellular_component	Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).
GO:0044294	dendritic growth cone	cellular_component	The migrating motile tip of a growing nerve cell dendrite.
GO:0044295	axonal growth cone	cellular_component	The migrating motile tip of a growing nerve cell axon.
GO:0044296	dendritic tuft	cellular_component	The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.
GO:0044297	cell body	cellular_component	The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
GO:0044298	cell body membrane	cellular_component	The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.
GO:0044299	C-fiber	cellular_component	The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.
GO:0044300	cerebellar mossy fiber	cellular_component	An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations.
GO:0044301	climbing fiber	cellular_component	The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.
GO:0044302	dentate gyrus mossy fiber	cellular_component	Distinctive, unmyelinated axons produced by dentate gyrus granule cells.
GO:0044303	axon collateral	cellular_component	Any of the smaller branches of an axon that emanate from the main axon cylinder.
GO:0044304	main axon	cellular_component	The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.
GO:0044305	calyx of Held	cellular_component	The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
GO:0044306	neuron projection terminus	cellular_component	The specialized, terminal region of a neuron projection such as an axon or a dendrite.
GO:0044307	dendritic branch	cellular_component	A dendrite arising from another dendrite.
GO:0044308	axonal spine	cellular_component	A spine that originates from the axon, usually from the initial segment.
GO:0044309	neuron spine	cellular_component	A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
GO:0044310	osmiophilic body	cellular_component	A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.
GO:0044311	exoneme	cellular_component	A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.
GO:0044312	crystalloid	cellular_component	A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation.
GO:0044313	protein K6-linked deubiquitination	biological_process	A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein.
GO:0044314	protein K27-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
GO:0044315	protein secretion by the type VII secretion system	biological_process	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system.
GO:0044316	cone cell pedicle	cellular_component	A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).
GO:0044317	rod spherule	cellular_component	A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.
GO:0044318	L-aspartate:fumarate oxidoreductase activity	molecular_function	Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate.
GO:0044319	wound healing, spreading of cells	biological_process	The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
GO:0044320	cellular response to leptin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.
GO:0044321	response to leptin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism].
GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.
GO:0044323	retinoic acid-responsive element binding	molecular_function	Binding to a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.
GO:0044325	transmembrane transporter binding	molecular_function	Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0044326	dendritic spine neck	cellular_component	Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.
GO:0044327	dendritic spine head	cellular_component	Distal part of the dendritic spine, that carries the post-synaptic density.
GO:0044328	canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration.
GO:0044329	canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion.
GO:0044330	canonical Wnt signaling pathway involved in positive regulation of wound healing	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing.
GO:0044331	cell-cell adhesion mediated by cadherin	biological_process	The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis.
GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract.
GO:0044334	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition.
GO:0044335	canonical Wnt signaling pathway involved in neural crest cell differentiation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation.
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process.
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process.
GO:0044338	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.
GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.
GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation.
GO:0044341	sodium-dependent phosphate transport	biological_process	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.
GO:0044342	type B pancreatic cell proliferation	biological_process	The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.
GO:0044343	canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin.
GO:0044344	cellular response to fibroblast growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	biological_process	The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.
GO:0044346	fibroblast apoptotic process	biological_process	Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0044347	cell wall polysaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.
GO:0044348	plant-type cell wall cellulose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.
GO:0044349	DNA excision	biological_process	The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.
GO:0044350	micropinocytosis	biological_process	An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm.
GO:0044351	macropinocytosis	biological_process	An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
GO:0044352	pinosome	cellular_component	A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis.
GO:0044353	micropinosome	cellular_component	A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis.
GO:0044354	macropinosome	cellular_component	A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
GO:0044355	clearance of foreign intracellular DNA	biological_process	A defense process that protects an organism from invading foreign DNA.
GO:0044357	regulation of rRNA stability	biological_process	Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.
GO:0044358	envenomation resulting in hemorrhagic damage in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.
GO:0044359	modulation of molecular function in another organism	biological_process	The process in which an organism effects a change in the function of proteins in a second organism.
GO:0044360	modulation of voltage-gated potassium channel activity in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.
GO:0044361	negative regulation of voltage-gated potassium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.
GO:0044362	negative regulation of molecular function in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.
GO:0044363	modulation of potassium channel activity in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism.
GO:0044365	envenomation resulting in modulation of platelet aggregation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism.
GO:0044373	cytokinin binding	molecular_function	Binding to a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators.
GO:0044374	sequence-specific DNA binding, bending	molecular_function	The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0044375	regulation of peroxisome size	biological_process	Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GO:0044377	RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending	molecular_function	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0044378	non-sequence-specific DNA binding, bending	molecular_function	The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0044379	protein localization to actin cortical patch	biological_process	A process in which a protein is transported to, or maintained in, an actin cortical patch.
GO:0044380	protein localization to cytoskeleton	biological_process	A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.
GO:0044381	glucose import in response to insulin stimulus	biological_process	The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.
GO:0044382	CLRC complex localization to heterochromatin	biological_process	The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation.
GO:0044383	host chromosome	cellular_component	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell.
GO:0044384	host outer membrane	cellular_component	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell.
GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	biological_process	The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.
GO:0044388	small protein activating enzyme binding	molecular_function	Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme.
GO:0044389	ubiquitin-like protein ligase binding	molecular_function	Binding to a ubiquitin-like protein ligase, such as ubiquitin-ligase.
GO:0044390	ubiquitin-like protein conjugating enzyme binding	molecular_function	Binding to a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.
GO:0044391	ribosomal subunit	cellular_component	Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.
GO:0044392	peptidyl-lysine malonylation	biological_process	The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.
GO:0044393	microspike	cellular_component	A dynamic, actin-rich projection extending from the surface of a migrating animal cell.
GO:0044394	protein malonylation	biological_process	The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.
GO:0044395	protein targeting to vacuolar membrane	biological_process	The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.
GO:0044396	actin cortical patch organization	biological_process	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.
GO:0044398	envenomation resulting in induction of edema in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation.
GO:0044399	multi-species biofilm formation	biological_process	A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0044403	biological process involved in symbiotic interaction	biological_process	A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
GO:0044405	detection of host	biological_process	The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044406	adhesion of symbiont to host	biological_process	The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044407	single-species biofilm formation in or on host organism	biological_process	A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044409	entry into host	biological_process	Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044414	suppression of host defenses by symbiont	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044416	induction by symbiont of host defense response	biological_process	The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044417	translocation of molecules into host	biological_process	The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044418	translocation of DNA into host	biological_process	The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044419	biological process involved in interspecies interaction between organisms	biological_process	Any process evolved to enable an interaction with an organism of a different species.
GO:0044423	virion component	cellular_component	Any constituent part of a virion, a complete fully infectious extracellular virus particle.
GO:0044458	motile cilium assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
GO:0044465	modulation of sensory perception of pain in another organism	biological_process	A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.
GO:0044466	glutaryl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate.
GO:0044467	glial cell-derived neurotrophic factor production	biological_process	The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.
GO:0044468	envenomation resulting in modulation of blood coagulation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism.
GO:0044469	envenomation resulting in positive regulation of blood coagulation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism.
GO:0044470	envenomation resulting in negative regulation of blood coagulation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.
GO:0044471	envenomation resulting in pore formation in membrane of another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism.
GO:0044472	envenomation resulting in modulation of calcium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.
GO:0044473	envenomation resulting in negative regulation of calcium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism.
GO:0044474	envenomation resulting in negative regulation of voltage-gated calcium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism.
GO:0044475	envenomation resulting in negative regulation of high voltage-gated calcium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism.
GO:0044476	envenomation resulting in negative regulation of low voltage-gated calcium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism.
GO:0044477	envenomation resulting in negative regulation of platelet aggregation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism.
GO:0044478	envenomation resulting in positive regulation of platelet aggregation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.
GO:0044479	envenomation resulting in modulation of mast cell degranulation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism.
GO:0044480	envenomation resulting in positive regulation of mast cell degranulation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.
GO:0044482	envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.
GO:0044483	envenomation resulting in impairment of hemostasis in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism.
GO:0044484	envenomation resulting in fibrinolysis in another organism	biological_process	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.
GO:0044485	envenomation resulting in fibrinogenolysis in another organism	biological_process	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism.
GO:0044486	modulation of transmission of nerve impulse in another organism	biological_process	The process in which an organism effects a change in the transmission of a nerve impulse in another organism.
GO:0044487	envenomation resulting in modulation of transmission of nerve impulse in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.
GO:0044488	modulation of voltage-gated sodium channel activity in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
GO:0044489	negative regulation of voltage-gated sodium channel activity in another organism	biological_process	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
GO:0044490	positive regulation of voltage-gated sodium channel activity in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
GO:0044491	positive regulation of molecular function in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism.
GO:0044492	envenomation resulting in modulation of voltage-gated sodium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism.
GO:0044493	envenomation resulting in negative regulation of voltage-gated sodium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism.
GO:0044494	envenomation resulting in positive regulation of voltage-gated sodium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism.
GO:0044495	modulation of blood pressure in another organism	biological_process	A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.
GO:0044496	negative regulation of blood pressure in another organism	biological_process	A process by which one organism decreases the force with which blood travels through the circulatory system of another organism.
GO:0044497	positive regulation of blood pressure in another organism	biological_process	A process by which one organism increases the force with which blood travels through the circulatory system of another organism.
GO:0044498	envenomation resulting in modulation of blood pressure in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism.
GO:0044499	envenomation resulting in positive regulation of blood pressure in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism.
GO:0044500	envenomation resulting in negative regulation of blood pressure in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.
GO:0044501	perturbation of signal transduction in another organism	biological_process	The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism.
GO:0044503	modulation of G protein-coupled receptor activity in another organism	biological_process	The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism.
GO:0044504	modulation of receptor activity in another organism	biological_process	The process in which an organism effects a change in the activity of a receptor in a second organism.
GO:0044505	positive regulation of G protein-coupled receptor activity in another organism	biological_process	A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism.
GO:0044506	modulation of glucagon-like peptide receptor 1 activity in another organism	biological_process	The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism.
GO:0044507	positive regulation of receptor activity in another organism	biological_process	A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism.
GO:0044508	glucagon-like peptide 1 receptor activity	molecular_function	Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.
GO:0044509	envenomation resulting in modulation of signal transduction in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism.
GO:0044510	envenomation resulting in positive regulation of signal transduction in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism.
GO:0044511	envenomation resulting in modulation of receptor activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism.
GO:0044512	envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism.
GO:0044513	envenomation resulting in modulation of G protein-coupled receptor activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism.
GO:0044514	envenomation resulting in positive regulation of G protein-coupled receptor activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism.
GO:0044515	envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism.
GO:0044516	positive regulation of glucagon-like peptide receptor 1 activity in another organism	biological_process	A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism.
GO:0044517	modulation of vasoactive intestinal polypeptide receptor activity in another organism	biological_process	The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism.
GO:0044518	positive regulation of vasoactive intestinal polypeptide receptor activity in another organism	biological_process	A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism.
GO:0044519	envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.
GO:0044520	envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.
GO:0044521	envenomation resulting in muscle damage in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.
GO:0044522	envenomation resulting in myocyte killing in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism.
GO:0044523	envenomation resulting in damage of muscle extracellular matrix in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism.
GO:0044524	protein sulfhydration	biological_process	The modification of a protein amino acid by the addition of sulfur.
GO:0044525	peptidyl-cystine sulfhydration	biological_process	The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.
GO:0044526	formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine	biological_process	The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.
GO:0044527	formation of peptidyl-cystine persulfide by sulphur transfer from H2S	biological_process	The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.
GO:0044528	regulation of mitochondrial mRNA stability	biological_process	Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.
GO:0044529	regulation of mitochondrial rRNA stability	biological_process	Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs.
GO:0044530	supraspliceosomal complex	cellular_component	Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.
GO:0044532	modulation of apoptotic process in another organism	biological_process	A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.
GO:0044533	positive regulation of apoptotic process in another organism	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism.
GO:0044534	envenomation resulting in modulation of apoptotic process in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism.
GO:0044535	very-long-chain fatty acyl-CoA oxidase activity	molecular_function	Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.
GO:0044536	envenomation resulting in depletion of circulating fibrinogen in another organism	biological_process	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism.
GO:0044537	regulation of circulating fibrinogen levels	biological_process	Any process that modulates the quantity of fibrinogen circulating in the bloodstream.
GO:0044538	host cell periphery	cellular_component	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.
GO:0044539	long-chain fatty acid import into cell	biological_process	The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0044540	L-cystine L-cysteine-lyase (deaminating)	molecular_function	Catalysis of the reaction: L-cystine + H2O = pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide.
GO:0044541	zymogen activation in another organism	biological_process	The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.
GO:0044542	plasminogen activation in another organism	biological_process	The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism.
GO:0044544	envenomation resulting in plasminogen activation in another organism	biological_process	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
GO:0044545	NSL complex	cellular_component	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.
GO:0044546	NLRP3 inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.
GO:0044547	DNA topoisomerase binding	molecular_function	Binding to a DNA topoisomerase.
GO:0044548	S100 protein binding	molecular_function	Binding to a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
GO:0044549	GTP cyclohydrolase binding	molecular_function	Binding to a GTP cyclohydrolase.
GO:0044550	secondary metabolite biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GO:0044551	envenomation resulting in vasodilation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism.
GO:0044552	vasodilation in another organism	biological_process	A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism.
GO:0044553	modulation of biological quality in another organism	biological_process	Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GO:0044554	modulation of heart rate in another organism	biological_process	Any process that modulates the frequency or rate of heart contraction of another organism.
GO:0044555	negative regulation of heart rate in another organism	biological_process	Any process that stops, prevents or reduces the frequency of heart contraction of another organism.
GO:0044556	envenomation resulting in negative regulation of heart rate in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism.
GO:0044557	relaxation of smooth muscle	biological_process	A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
GO:0044558	uterine smooth muscle relaxation	biological_process	A process in which the extent of smooth muscle contraction is reduced in the uterus.
GO:0044559	envenomation resulting in modulation of voltage-gated potassium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.
GO:0044560	envenomation resulting in modulation of ion channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism.
GO:0044561	modulation of ion channel activity in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism.
GO:0044562	envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.
GO:0044563	envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.
GO:0044564	envenomation resulting in occlusion of the pore of voltage-gated potassium channel in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism.
GO:0044565	dendritic cell proliferation	biological_process	The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
GO:0044566	chondrocyte activation	biological_process	A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.
GO:0044567	primary cell wall cellulose synthase complex	cellular_component	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.
GO:0044568	secondary cell wall cellulose synthase complex	cellular_component	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.
GO:0044569	[Ni-Fe] hydrogenase complex	cellular_component	A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.
GO:0044570	starch utilization system complex	cellular_component	A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.
GO:0044571	[2Fe-2S] cluster assembly	biological_process	The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.
GO:0044572	[4Fe-4S] cluster assembly	biological_process	The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
GO:0044573	nitrogenase P cluster assembly	biological_process	The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.
GO:0044574	starch utilization system complex assembly	biological_process	The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.
GO:0044575	cellulosome assembly	biological_process	The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.
GO:0044576	pentose catabolic process to ethanol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.
GO:0044577	xylose catabolic process to ethanol	biological_process	The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol.
GO:0044578	butyryl-CoA biosynthetic process	biological_process	The chemical reactions and pathway resulting in the formation of butyryl-CoA.
GO:0044579	butyryl-CoA biosynthetic process from acetyl-CoA	biological_process	The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.
GO:0044580	butyryl-CoA catabolic process	biological_process	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.
GO:0044581	butyryl-CoA catabolic process to butyrate	biological_process	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate.
GO:0044582	butyryl-CoA catabolic process to butanol	biological_process	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.
GO:0044583	cellotriose binding	molecular_function	Binding to cellotriose.
GO:0044584	cellodextrin binding	molecular_function	Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers.
GO:0044585	cellobiose binding	molecular_function	Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.
GO:0044586	cellotetraose binding	molecular_function	Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
GO:0044587	cellopentaose binding	molecular_function	Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
GO:0044588	laminaribiose binding	molecular_function	Binding to laminaribiose, a disaccharide.
GO:0044589	pectin binding	molecular_function	Binding to pectin.
GO:0044590	iron-sulfur-molybdenum cofactor binding	molecular_function	Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
GO:0044591	response to amylopectin	biological_process	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.
GO:0044592	response to pullulan	biological_process	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.
GO:0044593	iron-sulfur-molybdenum cofactor assembly	biological_process	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.
GO:0044595	decaprenyldihydroxybenzoate methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.
GO:0044596	3-demethylubiquinol-10 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10.
GO:0044597	daunorubicin metabolic process	biological_process	The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.
GO:0044598	doxorubicin metabolic process	biological_process	The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.
GO:0044599	AP-5 adaptor complex	cellular_component	An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.
GO:0044600	protein guanylyltransferase activity	molecular_function	Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.
GO:0044601	protein denucleotidylation	biological_process	The removal of a nucleotide from a protein amino acid.
GO:0044602	protein deadenylylation	biological_process	The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.
GO:0044603	protein adenylylhydrolase activity	molecular_function	Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.
GO:0044604	ABC-type phytochelatin transporter activity	molecular_function	Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
GO:0044605	phosphocholine transferase activity	molecular_function	Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.
GO:0044606	phosphocholine hydrolase activity	molecular_function	Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.
GO:0044609	DBIRD complex	cellular_component	A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.
GO:0044610	FMN transmembrane transporter activity	molecular_function	Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other.
GO:0044611	nuclear pore inner ring	cellular_component	A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.
GO:0044612	nuclear pore linkers	cellular_component	A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).
GO:0044613	nuclear pore central transport channel	cellular_component	The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
GO:0044614	nuclear pore cytoplasmic filaments	cellular_component	Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.
GO:0044615	nuclear pore nuclear basket	cellular_component	A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
GO:0044616	modulation of relaxation of muscle in another organism	biological_process	The process in which an organism effects a change in the relaxation of muscle in a second organism.
GO:0044617	modulation of relaxation of smooth muscle in another organism	biological_process	The process in which an organism effects a change in the relaxation of smooth muscle in a second organism.
GO:0044618	modulation of relaxation of uterine smooth muscle in another organism	biological_process	The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.
GO:0044619	positive regulation of relaxation of uterine smooth muscle in another organism	biological_process	The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.
GO:0044620	ACP phosphopantetheine attachment site binding	molecular_function	Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).
GO:0044621	modulation of cell migration in another organism	biological_process	The process in which an organism effects a change in the process of cell migration in a second organism.
GO:0044622	negative regulation of cell migration in another organism	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.
GO:0044623	positive regulation of cell migration in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of cell migration in a second organism.
GO:0044627	modulation of complement activation, classical pathway in another organism	biological_process	A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism.
GO:0044628	positive regulation of complement activation, classical pathway in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
GO:0044629	negative regulation of complement activation, classical pathway in another organism	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
GO:0044630	modulation of complement activation, lectin pathway in another organism	biological_process	A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism.
GO:0044631	positive regulation of complement activation, lectin pathway in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism.
GO:0044632	negative regulation of complement activation, lectin pathway in another organism	biological_process	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism.
GO:0044633	modulation of complement activation, alternative pathway in another organism	biological_process	A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.
GO:0044634	negative regulation of complement activation, alternative pathway in another organism	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
GO:0044635	positive regulation of complement activation, alternative pathway in another organism	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
GO:0044636	envenomation resulting in modulation of complement activation, classical pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism.
GO:0044637	envenomation resulting in negative regulation of complement activation, classical pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism.
GO:0044638	envenomation resulting in positive regulation of complement activation, classical pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism.
GO:0044639	envenomation resulting in modulation of complement activation, lectin pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.
GO:0044640	envenomation resulting in negative regulation of complement activation, lectin pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism.
GO:0044641	envenomation resulting in positive regulation of complement activation, lectin pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism.
GO:0044642	envenomation resulting in modulation of complement activation, alternative pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism.
GO:0044643	envenomation resulting in positive regulation of complement activation, alternative pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism.
GO:0044644	envenomation resulting in negative regulation of complement activation, alternative pathway in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.
GO:0044645	modulation of complement activation in another organism	biological_process	A process that modulates the frequency, rate or extent of complement activation in a different organism.
GO:0044646	envenomation resulting in modulation of complement activation in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism.
GO:0044647	host-symbiont bicellular tight junction	cellular_component	An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.
GO:0044648	histone H3-K4 dimethylation	biological_process	The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.
GO:0044650	adhesion of symbiont to host cell	biological_process	The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.
GO:0044651	adhesion of symbiont to host epithelial cell	biological_process	The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
GO:0044652	adhesion of symbiont to host endothelial cell	biological_process	The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
GO:0044653	dextrin alpha-glucosidase activity	molecular_function	Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.
GO:0044654	starch alpha-glucosidase activity	molecular_function	Catalysis of the reaction: starch + H2O = alpha-D-glucose.
GO:0044655	phagosome reneutralization	biological_process	Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation.
GO:0044656	regulation of post-lysosomal vacuole size	biological_process	Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.
GO:0044658	pore formation in host plasma membrane	biological_process	The disruption of host plasma membrane integrity by formation of a pore, resulting in deregulated ion homeostasis, and cellular dysfunction that can result in cell death.
GO:0044659	viral release from host cell by cytolysis	biological_process	The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm.
GO:0044660	viral release via pore formation in host cell membrane	biological_process	The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane.
GO:0044663	establishment or maintenance of cell type involved in phenotypic switching	biological_process	A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
GO:0044665	MLL1/2 complex	cellular_component	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.
GO:0044666	MLL3/4 complex	cellular_component	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.
GO:0044667	(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).
GO:0044668	sodium:malonate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).
GO:0044669	sodium:galactoside symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).
GO:0044671	sorocarp spore cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).
GO:0044672	acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	cellular_component	A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis.
GO:0044673	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex	cellular_component	A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.
GO:0044674	methyl coenzyme M reductase complex	cellular_component	A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.
GO:0044675	formyl-methanofuran dehydrogenase (tungsten enzyme) complex	cellular_component	A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
GO:0044676	formyl-methanofuran dehydrogenase (molybdenum enzyme) complex	cellular_component	A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
GO:0044677	methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex	cellular_component	A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.
GO:0044678	CoB-CoM heterodisulfide reductase complex	cellular_component	A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.
GO:0044679	methanophenazine reducing hydrogenase complex	cellular_component	A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.
GO:0044680	methylthiol:coenzyme M methyltransferase complex	cellular_component	A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis.
GO:0044681	sulfopyruvate decarboxylase complex	cellular_component	A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.
GO:0044682	archaeal-specific GTP cyclohydrolase activity	molecular_function	Catalysis of the reaction: GTP + H2O = 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.
GO:0044683	methylthiol:coenzyme M methyltransferase activity	molecular_function	Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.
GO:0044684	dihydromethanopterin reductase activity	molecular_function	Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.
GO:0044685	tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity	molecular_function	Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O.
GO:0044686	cysteate synthase activity	molecular_function	Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-.
GO:0044687	geranylfarnesyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.
GO:0044688	7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity	molecular_function	Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.
GO:0044689	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	molecular_function	Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.
GO:0044691	tooth eruption	biological_process	The tooth development process in which the teeth enter the mouth and become visible.
GO:0044692	exoribonuclease activator activity	molecular_function	Binds to and increases the activity of an exoribonuclease.
GO:0044693	trehalose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).
GO:0044694	pore-mediated entry of viral genome into host cell	biological_process	Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.
GO:0044695	Dsc E3 ubiquitin ligase complex	cellular_component	An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.
GO:0044696	killing by virus of host cell by post-segregational killing	biological_process	The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.
GO:0044697	HICS complex	cellular_component	A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.
GO:0044703	multi-organism reproductive process	biological_process	A biological process that directly contributes to the process of producing new individuals, involving another organism.
GO:0044706	multi-multicellular organism process	biological_process	A multicellular organism process which involves another multicellular organism of the same or different species.
GO:0044715	8-oxo-dGDP phosphatase activity	molecular_function	Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
GO:0044716	8-oxo-GDP phosphatase activity	molecular_function	Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.
GO:0044717	8-hydroxy-dADP phosphatase activity	molecular_function	Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate.
GO:0044718	siderophore transmembrane transport	biological_process	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.
GO:0044719	regulation of imaginal disc-derived wing size	biological_process	Any process that modulates the size of an imaginal disc-derived wing.
GO:0044720	negative regulation of imaginal disc-derived wing size	biological_process	Any process that reduces the size of an imaginal disc-derived wing.
GO:0044721	protein import into peroxisome matrix, substrate release	biological_process	The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.
GO:0044722	renal phosphate excretion	biological_process	The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
GO:0044725	epigenetic programming in the zygotic pronuclei	biological_process	The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.
GO:0044726	epigenetic programing of female pronucleus	biological_process	The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.
GO:0044727	epigenetic programing of male pronucleus	biological_process	The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division.
GO:0044729	hemi-methylated DNA-binding	molecular_function	Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
GO:0044730	bone sialoprotein binding	molecular_function	Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.
GO:0044731	Ost-alpha/Ost-beta complex	cellular_component	A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.
GO:0044732	mitotic spindle pole body	cellular_component	The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
GO:0044733	envenomation resulting in modulation of acid-sensing ion channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
GO:0044734	envenomation resulting in positive regulation of acid-sensing ion channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
GO:0044735	envenomation resulting in negative regulation of acid-sensing ion channel activity in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
GO:0044736	acid-sensing ion channel activity	molecular_function	Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
GO:0044737	modulation of acid-sensing ion channel in another organism	biological_process	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism.
GO:0044738	negative regulation of acid-sensing ion channel in another organism	biological_process	Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.
GO:0044739	positive regulation of acid-sensing ion channel in another organism	biological_process	Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism.
GO:0044740	negative regulation of sensory perception of pain in another organism	biological_process	A process that negatively regulates the sensory perception of pain in a different organism.
GO:0044741	envenomation resulting in negative regulation of sensory perception of pain in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.
GO:0044742	envenomation resulting in modulation of sensory perception of pain in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.
GO:0044743	protein transmembrane import into intracellular organelle	biological_process	The directed movement of proteins into an intracellular organelle, across a membrane.
GO:0044747	pre-miRNA 3'-end processing	biological_process	Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.
GO:0044748	3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.
GO:0044750	high-affinity nickel cation transmembrane transporter activity	molecular_function	Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0044751	cellular response to human chorionic gonadotropin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
GO:0044752	response to human chorionic gonadotropin	biological_process	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
GO:0044753	amphisome	cellular_component	Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.
GO:0044754	autolysosome	cellular_component	A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
GO:0044758	modulation by symbiont of host synaptic transmission	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.
GO:0044759	negative regulation by symbiont of host synaptic transmission	biological_process	Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.
GO:0044760	modulation by symbiont of host cholinergic synaptic transmission	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
GO:0044761	negative regulation by symbiont of host cholinergic synaptic transmission	biological_process	Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
GO:0044762	negative regulation by symbiont of host neurotransmitter secretion	biological_process	Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism.
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	molecular_function	Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.
GO:0044770	cell cycle phase transition	biological_process	The cell cycle process by which a cell commits to entering the next cell cycle phase.
GO:0044771	meiotic cell cycle phase transition	biological_process	The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.
GO:0044772	mitotic cell cycle phase transition	biological_process	The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
GO:0044773	mitotic DNA damage checkpoint signaling	biological_process	A signal transduction process involved in mitotic DNA damage checkpoint.
GO:0044774	mitotic DNA integrity checkpoint signaling	biological_process	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
GO:0044775	DNA polymerase III, beta sliding clamp processivity factor complex	cellular_component	A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.
GO:0044776	DNA polymerase III, core complex	cellular_component	The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.
GO:0044777	single-stranded DNA-binding protein complex	cellular_component	A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.
GO:0044778	meiotic DNA integrity checkpoint signaling	biological_process	A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
GO:0044779	meiotic spindle checkpoint signaling	biological_process	A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.
GO:0044780	bacterial-type flagellum assembly	biological_process	The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
GO:0044781	bacterial-type flagellum organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
GO:0044782	cilium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0044784	metaphase/anaphase transition of cell cycle	biological_process	The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.
GO:0044785	metaphase/anaphase transition of meiotic cell cycle	biological_process	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.
GO:0044786	cell cycle DNA replication	biological_process	The DNA-dependent DNA replication that takes place as part of the cell cycle.
GO:0044787	bacterial-type DNA replication	biological_process	The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.
GO:0044788	modulation by host of viral process	biological_process	A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected.
GO:0044790	suppression of viral release by host	biological_process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
GO:0044793	negative regulation by host of viral process	biological_process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.
GO:0044794	positive regulation by host of viral process	biological_process	A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected.
GO:0044795	trans-Golgi network to recycling endosome transport	biological_process	The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes.
GO:0044796	DNA polymerase processivity factor complex	cellular_component	A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.
GO:0044799	NarGHI complex	cellular_component	A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit.
GO:0044804	nucleophagy	biological_process	A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.
GO:0044805	late nucleophagy	biological_process	A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.
GO:0044806	G-quadruplex DNA unwinding	biological_process	The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
GO:0044807	macrophage migration inhibitory factor production	biological_process	The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0044808	oncostatin M production	biological_process	The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0044809	chemokine (C-C motif) ligand 17 production	biological_process	The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0044812	fermentative hydrogen production	biological_process	The fermentation of organic substances with a net release of hydrogen.
GO:0044813	glycolytic fermentation via PFOR pathway	biological_process	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species.
GO:0044814	glycolytic fermentation via PFL pathway	biological_process	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli.
GO:0044816	Nsk1-Dlc1 complex	cellular_component	A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation.
GO:0044817	hydrogen generation via biophotolysis	biological_process	The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae.
GO:0044818	mitotic G2/M transition checkpoint	biological_process	A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.
GO:0044819	mitotic G1/S transition checkpoint signaling	biological_process	A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.
GO:0044820	mitotic telomere tethering at nuclear periphery	biological_process	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.
GO:0044821	meiotic telomere tethering at nuclear periphery	biological_process	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.
GO:0044823	retroviral integrase activity	molecular_function	Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.
GO:0044824	retroviral 3' processing activity	molecular_function	The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.
GO:0044826	viral genome integration into host DNA	biological_process	The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.
GO:0044827	modulation by host of viral genome replication	biological_process	A process in which a host organism modulates the frequency, rate or extent of viral genome replication.
GO:0044828	negative regulation by host of viral genome replication	biological_process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.
GO:0044829	positive regulation by host of viral genome replication	biological_process	A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication.
GO:0044830	modulation by host of viral RNA genome replication	biological_process	A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.
GO:0044831	modulation by virus of host cytokine production	biological_process	Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.
GO:0044832	induction by virus of host cytokine production	biological_process	The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.
GO:0044833	modulation by virus of host protein transport	biological_process	Any viral process that modulates the frequency, rate or extent of protein transport in its host organism.
GO:0044834	retroviral intasome	cellular_component	A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome.
GO:0044835	hydrogen generation via nitrogenase	biological_process	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.
GO:0044836	D-xylose fermentation	biological_process	The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.
GO:0044837	actomyosin contractile ring organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.
GO:0044838	cell quiescence	biological_process	A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.
GO:0044839	cell cycle G2/M phase transition	biological_process	The cell cycle process by which a cell in G2 phase commits to M phase.
GO:0044840	gut granule	cellular_component	A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.
GO:0044841	gut granule membrane	cellular_component	The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.
GO:0044842	gut granule lumen	cellular_component	The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.
GO:0044843	cell cycle G1/S phase transition	biological_process	The cell cycle process by which a cell in G1 phase commits to S phase.
GO:0044844	meiotic interphase II	biological_process	The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.
GO:0044845	chain elongation of O-linked mannose residue	biological_process	Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules.
GO:0044846	negative regulation by symbiont of indole acetic acid levels in host	biological_process	Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0044847	iron acquisition from host	biological_process	The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell.
GO:0044848	biological phase	biological_process	A distinct period or stage in a biological process or cycle.
GO:0044849	estrous cycle	biological_process	A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
GO:0044850	menstrual cycle	biological_process	A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.
GO:0044851	hair cycle phase	biological_process	The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
GO:0044853	plasma membrane raft	cellular_component	A membrane raft that is part of the plasma membrane.
GO:0044854	plasma membrane raft assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.
GO:0044855	plasma membrane raft distribution	biological_process	The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.
GO:0044856	plasma membrane raft localization	biological_process	Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.
GO:0044857	plasma membrane raft organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.
GO:0044858	plasma membrane raft polarization	biological_process	The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.
GO:0044859	protein insertion into plasma membrane raft	biological_process	The process in which a protein is incorporated into a plasma membrane raft.
GO:0044860	protein localization to plasma membrane raft	biological_process	A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.
GO:0044861	protein transport into plasma membrane raft	biological_process	The directed movement of a protein into a plasma membrane raft.
GO:0044862	protein transport out of plasma membrane raft	biological_process	The directed movement of a protein out of a plasma membrane raft.
GO:0044863	modulation by virus of host cell division	biological_process	Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells.
GO:0044864	positive regulation by virus of host cell division	biological_process	Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.
GO:0044865	negative regulation by virus of host cell division	biological_process	Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division.
GO:0044866	modulation by host of viral exo-alpha-sialidase activity	biological_process	The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.
GO:0044867	modulation by host of viral catalytic activity	biological_process	The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.
GO:0044868	modulation by host of viral molecular function	biological_process	A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.
GO:0044869	negative regulation by host of viral exo-alpha-sialidase activity	biological_process	The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.
GO:0044870	modulation by host of viral glycoprotein metabolic process	biological_process	A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.
GO:0044871	negative regulation by host of viral glycoprotein metabolic process	biological_process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process.
GO:0044872	lipoprotein localization	biological_process	Any process in which a lipoprotein is transported to, or maintained in, a specific location.
GO:0044873	lipoprotein localization to membrane	biological_process	A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.
GO:0044874	lipoprotein localization to outer membrane	biological_process	A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.
GO:0044875	gamma-glutamyl hercynylcysteine sulfoxide synthase activity	molecular_function	Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 = gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.
GO:0044876	hercynylselenocysteine synthase	molecular_function	Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 = 2 H2O + 2 hercynylselenocysteine.
GO:0044877	protein-containing complex binding	molecular_function	Binding to a macromolecular complex.
GO:0044878	mitotic cytokinesis checkpoint signaling	biological_process	A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.
GO:0044879	mitotic morphogenesis checkpoint signaling	biological_process	A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.
GO:0045002	double-strand break repair via single-strand annealing	biological_process	Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.
GO:0045003	double-strand break repair via synthesis-dependent strand annealing	biological_process	SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.
GO:0045004	DNA replication proofreading	biological_process	Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
GO:0045005	DNA-templated DNA replication maintenance of fidelity	biological_process	A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.
GO:0045006	DNA deamination	biological_process	The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.
GO:0045007	depurination	biological_process	The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar.
GO:0045008	depyrimidination	biological_process	The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.
GO:0045009	chitosome	cellular_component	An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.
GO:0045010	actin nucleation	biological_process	The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
GO:0045013	carbon catabolite repression of transcription	biological_process	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
GO:0045014	carbon catabolite repression of transcription by glucose	biological_process	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
GO:0045015	HDEL sequence binding	molecular_function	Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
GO:0045016	mitochondrial magnesium ion transmembrane transport	biological_process	The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0045017	glycerolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.
GO:0045018	retrograde transport, vacuole to Golgi	biological_process	The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment.
GO:0045019	negative regulation of nitric oxide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
GO:0045022	early endosome to late endosome transport	biological_process	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
GO:0045023	G0 to G1 transition	biological_process	The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.
GO:0045025	mitochondrial degradosome	cellular_component	A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.
GO:0045026	plasma membrane fusion	biological_process	The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.
GO:0045027	DNA end binding	molecular_function	Binding to DNA ends exposed by the creation of double-strand breaks (DSBs).
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	molecular_function	Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0045029	G protein-coupled UDP receptor activity	molecular_function	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.
GO:0045030	G protein-coupled UTP receptor activity	molecular_function	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.
GO:0045031	G protein-coupled ATP receptor activity	molecular_function	Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0045033	peroxisome inheritance	biological_process	The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.
GO:0045035	sensory organ precursor cell division	biological_process	The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).
GO:0045036	protein targeting to chloroplast	biological_process	The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.
GO:0045037	protein import into chloroplast stroma	biological_process	The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.
GO:0045038	protein import into chloroplast thylakoid membrane	biological_process	The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma.
GO:0045039	protein insertion into mitochondrial inner membrane	biological_process	The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.
GO:0045040	protein insertion into mitochondrial outer membrane	biological_process	The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.
GO:0045041	protein import into mitochondrial intermembrane space	biological_process	The import of proteins into the space between the inner and outer mitochondrial membranes.
GO:0045046	protein import into peroxisome membrane	biological_process	The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.
GO:0045047	protein targeting to ER	biological_process	The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
GO:0045048	protein insertion into ER membrane	biological_process	The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.
GO:0045049	protein insertion into ER membrane by N-terminal cleaved signal sequence	biological_process	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.
GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	biological_process	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix.
GO:0045051	protein insertion into ER membrane by internal uncleaved signal-anchor sequence	biological_process	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences.
GO:0045053	protein retention in Golgi apparatus	biological_process	The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.
GO:0045054	constitutive secretory pathway	biological_process	A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.
GO:0045055	regulated exocytosis	biological_process	A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.
GO:0045056	transcytosis	biological_process	The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.
GO:0045057	cisternal progression	biological_process	The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna.
GO:0045058	T cell selection	biological_process	The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.
GO:0045059	positive thymic T cell selection	biological_process	The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death.
GO:0045060	negative thymic T cell selection	biological_process	The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
GO:0045061	thymic T cell selection	biological_process	The process of T cell selection that occurs in the thymus.
GO:0045062	extrathymic T cell selection	biological_process	The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus.
GO:0045063	T-helper 1 cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
GO:0045064	T-helper 2 cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.
GO:0045065	cytotoxic T cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
GO:0045066	regulatory T cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.
GO:0045067	positive extrathymic T cell selection	biological_process	The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
GO:0045068	negative extrathymic T cell selection	biological_process	The process of elimination of extrathymically maturing T cells which react strongly with self-antigens.
GO:0045069	regulation of viral genome replication	biological_process	Any process that modulates the frequency, rate or extent of viral genome replication.
GO:0045070	positive regulation of viral genome replication	biological_process	Any process that activates or increases the frequency, rate or extent of viral genome replication.
GO:0045071	negative regulation of viral genome replication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
GO:0045087	innate immune response	biological_process	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0045088	regulation of innate immune response	biological_process	Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
GO:0045089	positive regulation of innate immune response	biological_process	Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	biological_process	Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
GO:0045092	interleukin-18 receptor complex	cellular_component	A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.
GO:0045095	keratin filament	cellular_component	A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.
GO:0045098	type III intermediate filament	cellular_component	A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments.
GO:0045103	intermediate filament-based process	biological_process	Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.
GO:0045104	intermediate filament cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.
GO:0045105	intermediate filament polymerization or depolymerization	biological_process	Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.
GO:0045106	intermediate filament depolymerization	biological_process	Disassembly of intermediate filaments by the removal of component monomers from a filament.
GO:0045107	intermediate filament polymerization	biological_process	Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
GO:0045108	regulation of intermediate filament polymerization or depolymerization	biological_process	Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.
GO:0045109	intermediate filament organization	biological_process	Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
GO:0045110	intermediate filament bundle assembly	biological_process	The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.
GO:0045111	intermediate filament cytoskeleton	cellular_component	Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
GO:0045112	integrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.
GO:0045113	regulation of integrin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
GO:0045114	beta 2 integrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.
GO:0045115	regulation of beta 2 integrin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
GO:0045116	protein neddylation	biological_process	Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
GO:0045117	azole transmembrane transport	biological_process	The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.
GO:0045119	azole:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances.
GO:0045120	pronucleus	cellular_component	The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.
GO:0045121	membrane raft	cellular_component	Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
GO:0045122	aflatoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
GO:0045123	cellular extravasation	biological_process	The migration of a leukocyte from the blood vessels into the surrounding tissue.
GO:0045124	regulation of bone resorption	biological_process	Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
GO:0045125	bioactive lipid receptor activity	molecular_function	Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
GO:0045127	N-acetylglucosamine kinase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.
GO:0045128	negative regulation of reciprocal meiotic recombination	biological_process	Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
GO:0045129	NAD-independent histone deacetylase activity	molecular_function	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone.
GO:0045130	keratan sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.
GO:0045131	pre-mRNA branch point binding	molecular_function	Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site.
GO:0045132	meiotic chromosome segregation	biological_process	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
GO:0045133	2,3-dihydroxybenzoate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
GO:0045134	UDP phosphatase activity	molecular_function	Catalysis of the reaction: UDP + H2O = UMP + phosphate.
GO:0045135	poly(beta-D-mannuronate) lyase activity	molecular_function	Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
GO:0045136	development of secondary sexual characteristics	biological_process	The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.
GO:0045137	development of primary sexual characteristics	biological_process	The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.
GO:0045138	nematode male tail tip morphogenesis	biological_process	The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
GO:0045140	inositol phosphoceramide synthase activity	molecular_function	Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol.
GO:0045141	meiotic telomere clustering	biological_process	The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.
GO:0045142	triplex DNA binding	molecular_function	Binding to a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination.
GO:0045143	homologous chromosome segregation	biological_process	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
GO:0045144	meiotic sister chromatid segregation	biological_process	The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.
GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	molecular_function	Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.
GO:0045146	initiation of acetate catabolic process by acetate	biological_process	The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045147	regulation of initiation of acetate catabolic process by acetate	biological_process	Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045148	tripeptide aminopeptidase activity	molecular_function	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.
GO:0045149	acetoin metabolic process	biological_process	The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.
GO:0045150	acetoin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.
GO:0045151	acetoin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.
GO:0045152	antisigma factor binding	molecular_function	Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
GO:0045156	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	molecular_function	Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis.
GO:0045157	electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity	molecular_function	Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis.
GO:0045158	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity	molecular_function	Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II.
GO:0045159	myosin II binding	molecular_function	Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.
GO:0045160	myosin I complex	cellular_component	A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.
GO:0045161	neuronal ion channel clustering	biological_process	The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
GO:0045162	clustering of voltage-gated sodium channels	biological_process	The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
GO:0045163	clustering of voltage-gated potassium channels	biological_process	The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.
GO:0045165	cell fate commitment	biological_process	The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.
GO:0045167	asymmetric protein localization involved in cell fate determination	biological_process	Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
GO:0045168	cell-cell signaling involved in cell fate commitment	biological_process	Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.
GO:0045169	fusome	cellular_component	A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.
GO:0045170	spectrosome	cellular_component	A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.
GO:0045171	intercellular bridge	cellular_component	A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
GO:0045172	germline ring canal	cellular_component	Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
GO:0045173	O-sialoglycoprotein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.
GO:0045174	glutathione dehydrogenase (ascorbate) activity	molecular_function	Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
GO:0045175	basal protein localization	biological_process	Any process in which a protein is transported to, or maintained in, basal regions of the cell.
GO:0045176	apical protein localization	biological_process	Any process in which a protein is transported to, or maintained in, apical regions of the cell.
GO:0045177	apical part of cell	cellular_component	The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
GO:0045178	basal part of cell	cellular_component	The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
GO:0045179	apical cortex	cellular_component	The region that lies just beneath the plasma membrane on the apical edge of a cell.
GO:0045180	basal cortex	cellular_component	The region that lies just beneath the plasma membrane on the basal edge of a cell.
GO:0045181	glutamate synthase activity, NAD(P)H as acceptor	molecular_function	Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.
GO:0045182	translation regulator activity	molecular_function	Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
GO:0045183	translation factor activity, non-nucleic acid binding	molecular_function	A translation regulator activity that does not involve binding to nucleic acids.
GO:0045184	establishment of protein localization	biological_process	The directed movement of a protein to a specific location.
GO:0045185	maintenance of protein location	biological_process	Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.
GO:0045186	zonula adherens assembly	biological_process	Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
GO:0045187	regulation of circadian sleep/wake cycle, sleep	biological_process	Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	biological_process	Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.
GO:0045190	isotype switching	biological_process	The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
GO:0045191	regulation of isotype switching	biological_process	Any process that modulates the frequency, rate or extent of isotype switching.
GO:0045196	establishment or maintenance of neuroblast polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
GO:0045198	establishment of epithelial cell apical/basal polarity	biological_process	The specification and formation of the apicobasal polarity of an epithelial cell.
GO:0045199	maintenance of epithelial cell apical/basal polarity	biological_process	The maintenance of the apicobasal polarity of an epithelial cell.
GO:0045200	establishment of neuroblast polarity	biological_process	The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
GO:0045201	maintenance of neuroblast polarity	biological_process	The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
GO:0045202	synapse	cellular_component	The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GO:0045204	MAPK export from nucleus	biological_process	The directed movement of a MAP kinase from the nucleus to the cytoplasm.
GO:0045208	MAPK phosphatase export from nucleus	biological_process	The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm.
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	biological_process	Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.
GO:0045210	FasL biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.
GO:0045211	postsynaptic membrane	cellular_component	A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
GO:0045213	neurotransmitter receptor metabolic process	biological_process	The chemical reactions and pathways involving neurotransmitter receptors.
GO:0045214	sarcomere organization	biological_process	The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
GO:0045216	cell-cell junction organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
GO:0045217	cell-cell junction maintenance	biological_process	The maintenance of junctions between cells.
GO:0045218	zonula adherens maintenance	biological_process	Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.
GO:0045219	regulation of FasL production	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
GO:0045220	positive regulation of FasL production	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
GO:0045221	negative regulation of FasL production	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
GO:0045222	CD4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.
GO:0045223	regulation of CD4 production	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
GO:0045224	positive regulation of CD4 production	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
GO:0045225	negative regulation of CD4 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
GO:0045226	extracellular polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.
GO:0045227	capsule polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0045228	slime layer polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.
GO:0045229	external encapsulating structure organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.
GO:0045230	capsule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0045231	slime layer organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.
GO:0045232	S-layer organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria.
GO:0045234	protein palmitoleylation	biological_process	The covalent attachment of a palmitoleyl group to a protein.
GO:0045236	CXCR chemokine receptor binding	molecular_function	Binding to a chemokine receptor in the CXCR family.
GO:0045237	CXCR1 chemokine receptor binding	molecular_function	Binding to a CXCR1 chemokine receptor.
GO:0045238	CXCR2 chemokine receptor binding	molecular_function	Binding to a CXCR2 chemokine receptor.
GO:0045239	tricarboxylic acid cycle enzyme complex	cellular_component	Any of the heteromeric enzymes that act in the TCA cycle.
GO:0045240	dihydrolipoyl dehydrogenase complex	cellular_component	A protein complex that possesses alpha-ketoglutarate dehydrogenase activity.
GO:0045241	cytosolic alpha-ketoglutarate dehydrogenase complex	cellular_component	Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.
GO:0045242	isocitrate dehydrogenase complex (NAD+)	cellular_component	Complex that possesses isocitrate dehydrogenase (NAD+) activity.
GO:0045243	cytosolic isocitrate dehydrogenase complex (NAD+)	cellular_component	Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity.
GO:0045244	succinate-CoA ligase complex (GDP-forming)	cellular_component	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.
GO:0045246	cytosolic tricarboxylic acid cycle enzyme complex	cellular_component	Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle.
GO:0045247	cytosolic electron transfer flavoprotein complex	cellular_component	A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors.
GO:0045248	cytosolic oxoglutarate dehydrogenase complex	cellular_component	A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
GO:0045249	cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex	cellular_component	A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
GO:0045250	cytosolic pyruvate dehydrogenase complex	cellular_component	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.
GO:0045251	electron transfer flavoprotein complex	cellular_component	A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system.
GO:0045252	oxoglutarate dehydrogenase complex	cellular_component	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
GO:0045253	pyruvate dehydrogenase (lipoamide) phosphatase complex	cellular_component	A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
GO:0045254	pyruvate dehydrogenase complex	cellular_component	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
GO:0045257	succinate dehydrogenase complex (ubiquinone)	cellular_component	The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.
GO:0045258	plasma membrane succinate dehydrogenase complex (ubiquinone)	cellular_component	The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.
GO:0045259	proton-transporting ATP synthase complex	cellular_component	A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.
GO:0045260	plasma membrane proton-transporting ATP synthase complex	cellular_component	A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.
GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	cellular_component	The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.
GO:0045262	plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)	cellular_component	The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	cellular_component	All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.
GO:0045264	plasma membrane proton-transporting ATP synthase complex, coupling factor F(o)	cellular_component	All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.
GO:0045265	proton-transporting ATP synthase, stator stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.
GO:0045266	plasma membrane proton-transporting ATP synthase, stator stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species.
GO:0045267	proton-transporting ATP synthase, catalytic core	cellular_component	The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
GO:0045268	plasma membrane proton-transporting ATP synthase, catalytic core	cellular_component	The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species.
GO:0045269	proton-transporting ATP synthase, central stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.
GO:0045270	plasma membrane proton-transporting ATP synthase, central stalk	cellular_component	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species.
GO:0045271	respiratory chain complex I	cellular_component	Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.
GO:0045272	plasma membrane respiratory chain complex I	cellular_component	A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.
GO:0045273	respiratory chain complex II	cellular_component	A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
GO:0045274	plasma membrane respiratory chain complex II	cellular_component	A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species.
GO:0045275	respiratory chain complex III	cellular_component	A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
GO:0045276	plasma membrane respiratory chain complex III	cellular_component	A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species.
GO:0045277	respiratory chain complex IV	cellular_component	A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
GO:0045278	plasma membrane respiratory chain complex IV	cellular_component	A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species.
GO:0045281	succinate dehydrogenase complex	cellular_component	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.
GO:0045282	plasma membrane succinate dehydrogenase complex	cellular_component	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species.
GO:0045283	fumarate reductase complex	cellular_component	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)).
GO:0045284	plasma membrane fumarate reductase complex	cellular_component	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.
GO:0045289	luciferin monooxygenase activity	molecular_function	Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.
GO:0045290	D-arabinose 1-dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.
GO:0045291	mRNA trans splicing, SL addition	biological_process	The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.
GO:0045292	mRNA cis splicing, via spliceosome	biological_process	The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
GO:0045293	mRNA editing complex	cellular_component	A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.
GO:0045294	alpha-catenin binding	molecular_function	Binding to catenin complex alpha subunit.
GO:0045295	gamma-catenin binding	molecular_function	Binding to catenin complex gamma subunit.
GO:0045296	cadherin binding	molecular_function	Binding to cadherin, a type I membrane protein involved in cell adhesion.
GO:0045298	tubulin complex	cellular_component	A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.
GO:0045299	otolith mineralization	biological_process	The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.
GO:0045300	acyl-[acyl-carrier-protein] desaturase activity	molecular_function	Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin.
GO:0045301	tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity	molecular_function	Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.
GO:0045302	choloylglycine hydrolase activity	molecular_function	Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
GO:0045303	diaminobutyrate-2-oxoglutarate transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate.
GO:0045304	regulation of establishment of competence for transformation	biological_process	Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.
GO:0045309	protein phosphorylated amino acid binding	molecular_function	Binding to a phosphorylated amino acid residue within a protein.
GO:0045311	invasive growth in response to pheromone	biological_process	The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.
GO:0045312	nor-spermidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0045313	rhabdomere membrane biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.
GO:0045314	regulation of compound eye photoreceptor development	biological_process	Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.
GO:0045315	positive regulation of compound eye photoreceptor development	biological_process	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.
GO:0045316	negative regulation of compound eye photoreceptor development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.
GO:0045317	equator specification	biological_process	The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
GO:0045320	chloroplast proton-transporting ATP synthase complex	cellular_component	A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.
GO:0045321	leukocyte activation	biological_process	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0045322	unmethylated CpG binding	molecular_function	Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters.
GO:0045323	interleukin-1 receptor complex	cellular_component	A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.
GO:0045324	late endosome to vacuole transport	biological_process	The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
GO:0045325	peptidyl-tryptophan hydroxylation	biological_process	The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.
GO:0045326	protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine	biological_process	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.
GO:0045327	protein-DNA covalent cross-linking via peptidyl-tyrosine	biological_process	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.
GO:0045328	cytochrome P450 4A1-heme linkage	biological_process	The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.
GO:0045329	carnitine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
GO:0045330	aspartyl esterase activity	molecular_function	Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.
GO:0045332	phospholipid translocation	biological_process	The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
GO:0045333	cellular respiration	biological_process	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
GO:0045334	clathrin-coated endocytic vesicle	cellular_component	A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
GO:0045335	phagocytic vesicle	cellular_component	A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
GO:0045336	clathrin-coated phagocytic vesicle	cellular_component	A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
GO:0045337	farnesyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
GO:0045338	farnesyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
GO:0045339	farnesyl diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.
GO:0045340	mercury ion binding	molecular_function	Binding to a mercury ion (Hg).
GO:0045341	MHC class I biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.
GO:0045342	MHC class II biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.
GO:0045343	regulation of MHC class I biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
GO:0045344	negative regulation of MHC class I biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
GO:0045345	positive regulation of MHC class I biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
GO:0045346	regulation of MHC class II biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
GO:0045347	negative regulation of MHC class II biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
GO:0045348	positive regulation of MHC class II biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
GO:0045352	interleukin-1 type I receptor antagonist activity	molecular_function	Blocks the binding of interleukin-1 to interleukin-1 type I receptors.
GO:0045353	interleukin-1 type II receptor antagonist activity	molecular_function	Blocks the binding of interleukin-1 to interleukin-1 type II receptors.
GO:0045428	regulation of nitric oxide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
GO:0045429	positive regulation of nitric oxide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
GO:0045430	chalcone isomerase activity	molecular_function	Catalysis of the reaction: a chalcone = a flavanone.
GO:0045431	flavonol synthase activity	molecular_function	Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
GO:0045433	male courtship behavior, veined wing generated song production	biological_process	The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
GO:0045434	negative regulation of female receptivity, post-mating	biological_process	Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.
GO:0045435	lycopene epsilon cyclase activity	molecular_function	Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).
GO:0045436	lycopene beta cyclase activity	molecular_function	Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.
GO:0045437	uridine nucleosidase activity	molecular_function	Catalysis of the reaction: H2O + uridine = ribofuranose + uracil.
GO:0045438	delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity	molecular_function	Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
GO:0045439	isopenicillin-N epimerase activity	molecular_function	Catalysis of the reaction: isopenicillin N = penicillin N.
GO:0045442	deacetoxycephalosporin-C hydroxylase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate.
GO:0045443	juvenile hormone secretion	biological_process	The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
GO:0045444	fat cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
GO:0045445	myoblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
GO:0045446	endothelial cell differentiation	biological_process	The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
GO:0045448	mitotic cell cycle, embryonic	biological_process	The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.
GO:0045450	bicoid mRNA localization	biological_process	Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.
GO:0045451	pole plasm oskar mRNA localization	biological_process	Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
GO:0045453	bone resorption	biological_process	The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
GO:0045454	cell redox homeostasis	biological_process	Any process that maintains the redox environment of a cell or compartment within a cell.
GO:0045455	ecdysteroid metabolic process	biological_process	The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.
GO:0045456	ecdysteroid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
GO:0045457	ecdysteroid secretion	biological_process	The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
GO:0045458	recombination within rDNA repeats	biological_process	Genetic recombination within the DNA of the genes coding for ribosomal RNA.
GO:0045459	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide	biological_process	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.
GO:0045460	sterigmatocystin metabolic process	biological_process	The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
GO:0045461	sterigmatocystin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
GO:0045462	trichothecene 3-O-acetyltransferase activity	molecular_function	Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.
GO:0045463	R8 cell development	biological_process	The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.
GO:0045464	R8 cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0045465	R8 cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.
GO:0045466	R7 cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.
GO:0045467	R7 cell development	biological_process	The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.
GO:0045468	regulation of R8 cell spacing in compound eye	biological_process	Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.
GO:0045469	negative regulation of R8 cell spacing in compound eye	biological_process	Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.
GO:0045470	R8 cell-mediated photoreceptor organization	biological_process	The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.
GO:0045471	response to ethanol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
GO:0045472	response to ether	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
GO:0045475	locomotor rhythm	biological_process	The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
GO:0045476	nurse cell apoptotic process	biological_process	Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
GO:0045477	regulation of nurse cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.
GO:0045478	fusome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.
GO:0045479	vesicle targeting to fusome	biological_process	The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.
GO:0045480	galactose oxidase activity	molecular_function	Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.
GO:0045481	6-endo-hydroxycineole dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.
GO:0045482	trichodiene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.
GO:0045483	aristolochene synthase activity	molecular_function	Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.
GO:0045484	L-lysine 6-transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.
GO:0045485	omega-6 fatty acid desaturase activity	molecular_function	Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.
GO:0045486	naringenin 3-dioxygenase activity	molecular_function	Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.
GO:0045487	gibberellin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
GO:0045488	pectin metabolic process	biological_process	The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.
GO:0045489	pectin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
GO:0045490	pectin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
GO:0045491	xylan metabolic process	biological_process	The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
GO:0045492	xylan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
GO:0045493	xylan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
GO:0045494	photoreceptor cell maintenance	biological_process	Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
GO:0045495	pole plasm	cellular_component	Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
GO:0045496	male analia development	biological_process	The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
GO:0045497	female analia development	biological_process	The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
GO:0045498	sex comb development	biological_process	The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.
GO:0045499	chemorepellent activity	molecular_function	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
GO:0045500	sevenless signaling pathway	biological_process	The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0045501	regulation of sevenless signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.
GO:0045503	dynein light chain binding	molecular_function	Binding to a light chain of the dynein complex.
GO:0045504	dynein heavy chain binding	molecular_function	Binding to a heavy chain of the dynein complex.
GO:0045505	dynein intermediate chain binding	molecular_function	Binding to an intermediate chain of the dynein complex.
GO:0045506	interleukin-24 receptor activity	molecular_function	Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0045507	interleukin-25 receptor activity	molecular_function	Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0045508	interleukin-26 receptor activity	molecular_function	Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0045509	interleukin-27 receptor activity	molecular_function	Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0045510	interleukin-24 binding	molecular_function	Binding to interleukin-24.
GO:0045511	interleukin-25 binding	molecular_function	Binding to interleukin-25.
GO:0045512	interleukin-26 binding	molecular_function	Binding to interleukin-26.
GO:0045513	interleukin-27 binding	molecular_function	Binding to interleukin-27.
GO:0045514	interleukin-16 receptor binding	molecular_function	Binding to an interleukin-16 receptor.
GO:0045515	interleukin-18 receptor binding	molecular_function	Binding to an interleukin-18 receptor.
GO:0045516	interleukin-19 receptor binding	molecular_function	Binding to an interleukin-19 receptor.
GO:0045517	interleukin-20 receptor binding	molecular_function	Binding to an interleukin-20 receptor.
GO:0045518	interleukin-22 receptor binding	molecular_function	Binding to an interleukin-22 receptor.
GO:0045519	interleukin-23 receptor binding	molecular_function	Binding to an interleukin-23 receptor.
GO:0045520	interleukin-24 receptor binding	molecular_function	Binding to an interleukin-24 receptor.
GO:0045521	interleukin-25 receptor binding	molecular_function	Binding to an interleukin-25 receptor.
GO:0045522	interleukin-26 receptor binding	molecular_function	Binding to an interleukin-26 receptor.
GO:0045523	interleukin-27 receptor binding	molecular_function	Binding to an interleukin-27 receptor.
GO:0045540	regulation of cholesterol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
GO:0045541	negative regulation of cholesterol biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
GO:0045542	positive regulation of cholesterol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
GO:0045543	gibberellin 2-beta-dioxygenase activity	molecular_function	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.
GO:0045544	gibberellin 20-oxidase activity	molecular_function	Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones.
GO:0045545	syndecan binding	molecular_function	Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
GO:0045547	dehydrodolichyl diphosphate synthase activity	molecular_function	Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.
GO:0045548	phenylalanine ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-phenylalanine = NH4 + trans-cinnamate.
GO:0045549	9-cis-epoxycarotenoid dioxygenase activity	molecular_function	Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.
GO:0045550	geranylgeranyl reductase activity	molecular_function	Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.
GO:0045551	cinnamyl-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+.
GO:0045552	dihydrokaempferol 4-reductase activity	molecular_function	Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+.
GO:0045569	TRAIL binding	molecular_function	Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
GO:0045570	regulation of imaginal disc growth	biological_process	Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.
GO:0045571	negative regulation of imaginal disc growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
GO:0045572	positive regulation of imaginal disc growth	biological_process	Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
GO:0045574	sterigmatocystin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
GO:0045575	basophil activation	biological_process	The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.
GO:0045576	mast cell activation	biological_process	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
GO:0045577	regulation of B cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of B cell differentiation.
GO:0045578	negative regulation of B cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
GO:0045579	positive regulation of B cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of B cell differentiation.
GO:0045580	regulation of T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of T cell differentiation.
GO:0045581	negative regulation of T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.
GO:0045582	positive regulation of T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of T cell differentiation.
GO:0045583	regulation of cytotoxic T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation.
GO:0045584	negative regulation of cytotoxic T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.
GO:0045585	positive regulation of cytotoxic T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.
GO:0045586	regulation of gamma-delta T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.
GO:0045587	negative regulation of gamma-delta T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.
GO:0045588	positive regulation of gamma-delta T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
GO:0045589	regulation of regulatory T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.
GO:0045590	negative regulation of regulatory T cell differentiation	biological_process	Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
GO:0045591	positive regulation of regulatory T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
GO:0045592	regulation of cumulus cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.
GO:0045593	negative regulation of cumulus cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.
GO:0045594	positive regulation of cumulus cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.
GO:0045595	regulation of cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
GO:0045596	negative regulation of cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
GO:0045597	positive regulation of cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cell differentiation.
GO:0045598	regulation of fat cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of adipocyte differentiation.
GO:0045599	negative regulation of fat cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
GO:0045600	positive regulation of fat cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
GO:0045601	regulation of endothelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell differentiation.
GO:0045602	negative regulation of endothelial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
GO:0045603	positive regulation of endothelial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.
GO:0045604	regulation of epidermal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
GO:0045605	negative regulation of epidermal cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
GO:0045606	positive regulation of epidermal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.
GO:0045607	regulation of inner ear auditory receptor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.
GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.
GO:0045609	positive regulation of inner ear auditory receptor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.
GO:0045610	regulation of hemocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of hemocyte differentiation.
GO:0045611	negative regulation of hemocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.
GO:0045612	positive regulation of hemocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.
GO:0045613	regulation of plasmatocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.
GO:0045614	negative regulation of plasmatocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.
GO:0045615	positive regulation of plasmatocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.
GO:0045616	regulation of keratinocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
GO:0045617	negative regulation of keratinocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
GO:0045618	positive regulation of keratinocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
GO:0045619	regulation of lymphocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of lymphocyte differentiation.
GO:0045620	negative regulation of lymphocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.
GO:0045621	positive regulation of lymphocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
GO:0045622	regulation of T-helper cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of T-helper cell differentiation.
GO:0045623	negative regulation of T-helper cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.
GO:0045624	positive regulation of T-helper cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
GO:0045625	regulation of T-helper 1 cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.
GO:0045626	negative regulation of T-helper 1 cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
GO:0045627	positive regulation of T-helper 1 cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
GO:0045628	regulation of T-helper 2 cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation.
GO:0045629	negative regulation of T-helper 2 cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
GO:0045630	positive regulation of T-helper 2 cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
GO:0045631	regulation of mechanoreceptor differentiation	biological_process	Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.
GO:0045632	negative regulation of mechanoreceptor differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.
GO:0045633	positive regulation of mechanoreceptor differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.
GO:0045634	regulation of melanocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of melanocyte differentiation.
GO:0045635	negative regulation of melanocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.
GO:0045636	positive regulation of melanocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
GO:0045637	regulation of myeloid cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
GO:0045638	negative regulation of myeloid cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
GO:0045639	positive regulation of myeloid cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
GO:0045640	regulation of basophil differentiation	biological_process	Any process that modulates the frequency, rate or extent of basophil differentiation.
GO:0045641	negative regulation of basophil differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.
GO:0045642	positive regulation of basophil differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of basophil differentiation.
GO:0045643	regulation of eosinophil differentiation	biological_process	Any process that modulates the frequency, rate or extent of eosinophil differentiation.
GO:0045644	negative regulation of eosinophil differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.
GO:0045645	positive regulation of eosinophil differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
GO:0045646	regulation of erythrocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of erythrocyte differentiation.
GO:0045647	negative regulation of erythrocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
GO:0045648	positive regulation of erythrocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
GO:0045649	regulation of macrophage differentiation	biological_process	Any process that modulates the frequency, rate or extent of macrophage differentiation.
GO:0045650	negative regulation of macrophage differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.
GO:0045651	positive regulation of macrophage differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
GO:0045652	regulation of megakaryocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
GO:0045653	negative regulation of megakaryocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
GO:0045654	positive regulation of megakaryocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.
GO:0045655	regulation of monocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of monocyte differentiation.
GO:0045656	negative regulation of monocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.
GO:0045657	positive regulation of monocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
GO:0045658	regulation of neutrophil differentiation	biological_process	Any process that modulates the frequency, rate or extent of neutrophil differentiation.
GO:0045659	negative regulation of neutrophil differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.
GO:0045660	positive regulation of neutrophil differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.
GO:0045661	regulation of myoblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0045662	negative regulation of myoblast differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0045663	positive regulation of myoblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0045664	regulation of neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of neuron differentiation.
GO:0045665	negative regulation of neuron differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
GO:0045666	positive regulation of neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of neuron differentiation.
GO:0045667	regulation of osteoblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of osteoblast differentiation.
GO:0045668	negative regulation of osteoblast differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.
GO:0045669	positive regulation of osteoblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
GO:0045670	regulation of osteoclast differentiation	biological_process	Any process that modulates the frequency, rate or extent of osteoclast differentiation.
GO:0045671	negative regulation of osteoclast differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
GO:0045672	positive regulation of osteoclast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
GO:0045676	regulation of R7 cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of R7 differentiation.
GO:0045677	negative regulation of R7 cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.
GO:0045678	positive regulation of R7 cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.
GO:0045679	regulation of R8 cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of R8 differentiation.
GO:0045680	negative regulation of R8 cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation.
GO:0045681	positive regulation of R8 cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.
GO:0045682	regulation of epidermis development	biological_process	Any process that modulates the frequency, rate or extent of epidermis development.
GO:0045683	negative regulation of epidermis development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.
GO:0045684	positive regulation of epidermis development	biological_process	Any process that activates or increases the frequency, rate or extent of epidermis development.
GO:0045685	regulation of glial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of glia cell differentiation.
GO:0045686	negative regulation of glial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.
GO:0045687	positive regulation of glial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of glia cell differentiation.
GO:0045688	regulation of antipodal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of antipodal cell differentiation.
GO:0045689	negative regulation of antipodal cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.
GO:0045690	positive regulation of antipodal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation.
GO:0045691	regulation of embryo sac central cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation.
GO:0045692	negative regulation of embryo sac central cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation.
GO:0045693	positive regulation of embryo sac central cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.
GO:0045694	regulation of embryo sac egg cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation.
GO:0045695	negative regulation of embryo sac egg cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.
GO:0045696	positive regulation of embryo sac egg cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.
GO:0045697	regulation of synergid differentiation	biological_process	Any process that modulates the frequency, rate or extent of synergid cell differentiation.
GO:0045698	negative regulation of synergid differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation.
GO:0045699	positive regulation of synergid differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.
GO:0045700	regulation of spermatid nuclear differentiation	biological_process	Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.
GO:0045701	negative regulation of spermatid nuclear differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.
GO:0045702	positive regulation of spermatid nuclear differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.
GO:0045703	ketoreductase activity	molecular_function	Catalysis of the reduction of a ketone group to form the corresponding alcohol.
GO:0045704	regulation of salivary gland boundary specification	biological_process	Any process that modulates the frequency, rate or extent of salivary gland determination.
GO:0045705	negative regulation of salivary gland boundary specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.
GO:0045706	positive regulation of salivary gland boundary specification	biological_process	Any process that activates or increases the frequency, rate or extent of salivary gland determination.
GO:0045707	regulation of adult salivary gland boundary specification	biological_process	Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism.
GO:0045708	regulation of larval salivary gland boundary specification	biological_process	Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism.
GO:0045709	negative regulation of adult salivary gland boundary specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.
GO:0045710	negative regulation of larval salivary gland boundary specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.
GO:0045711	positive regulation of adult salivary gland boundary specification	biological_process	Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.
GO:0045712	positive regulation of larval salivary gland boundary specification	biological_process	Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism.
GO:0045717	negative regulation of fatty acid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
GO:0045719	negative regulation of glycogen biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
GO:0045720	negative regulation of integrin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
GO:0045721	negative regulation of gluconeogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
GO:0045722	positive regulation of gluconeogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
GO:0045723	positive regulation of fatty acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
GO:0045724	positive regulation of cilium assembly	biological_process	Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
GO:0045725	positive regulation of glycogen biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
GO:0045726	positive regulation of integrin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
GO:0045727	positive regulation of translation	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0045728	respiratory burst after phagocytosis	biological_process	A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.
GO:0045729	respiratory burst at fertilization	biological_process	The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.
GO:0045730	respiratory burst	biological_process	A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0045732	positive regulation of protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0045733	acetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.
GO:0045734	regulation of acetate catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.
GO:0045735	nutrient reservoir activity	molecular_function	Functions in the storage of nutritious substrates.
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of CDK activity.
GO:0045738	negative regulation of DNA repair	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.
GO:0045739	positive regulation of DNA repair	biological_process	Any process that activates or increases the frequency, rate or extent of DNA repair.
GO:0045740	positive regulation of DNA replication	biological_process	Any process that activates or increases the frequency, rate or extent of DNA replication.
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.
GO:0045746	negative regulation of Notch signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
GO:0045747	positive regulation of Notch signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
GO:0045748	positive regulation of R8 cell spacing in compound eye	biological_process	Any process that activates or enforces the correct R8 cell spacing in a compound eye.
GO:0045751	negative regulation of Toll signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.
GO:0045752	positive regulation of Toll signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.
GO:0045753	negative regulation of acetate catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045754	positive regulation of acetate catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045755	negative regulation of initiation of acetate catabolic process by acetate	biological_process	Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045756	positive regulation of initiation of acetate catabolic process by acetate	biological_process	Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
GO:0045759	negative regulation of action potential	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0045760	positive regulation of action potential	biological_process	Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0045761	regulation of adenylate cyclase activity	biological_process	Any process that modulates the frequency, rate or extent of adenylate cyclase activity.
GO:0045762	positive regulation of adenylate cyclase activity	biological_process	Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
GO:0045763	negative regulation of cellular amino acid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
GO:0045764	positive regulation of amino acid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
GO:0045765	regulation of angiogenesis	biological_process	Any process that modulates the frequency, rate or extent of angiogenesis.
GO:0045766	positive regulation of angiogenesis	biological_process	Any process that activates or increases angiogenesis.
GO:0045769	negative regulation of asymmetric cell division	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.
GO:0045770	positive regulation of asymmetric cell division	biological_process	Any process that activates or increases the frequency, rate or extent of asymmetric cell division.
GO:0045771	negative regulation of autophagosome size	biological_process	Any process that reduces autophagosome size.
GO:0045772	positive regulation of autophagosome size	biological_process	Any process that increases autophagosome size.
GO:0045773	positive regulation of axon extension	biological_process	Any process that activates or increases the frequency, rate or extent of axon extension.
GO:0045774	negative regulation of beta 2 integrin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
GO:0045775	positive regulation of beta 2 integrin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
GO:0045776	negative regulation of blood pressure	biological_process	Any process in which the force of blood traveling through the circulatory system is decreased.
GO:0045777	positive regulation of blood pressure	biological_process	Any process in which the force of blood traveling through the circulatory system is increased.
GO:0045778	positive regulation of ossification	biological_process	Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
GO:0045779	negative regulation of bone resorption	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.
GO:0045780	positive regulation of bone resorption	biological_process	Any process that activates or increases the frequency, rate or extent of bone resorption.
GO:0045781	negative regulation of cell budding	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.
GO:0045782	positive regulation of cell budding	biological_process	Any process that activates or increases the frequency, rate or extent of cell budding.
GO:0045785	positive regulation of cell adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of cell adhesion.
GO:0045786	negative regulation of cell cycle	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
GO:0045787	positive regulation of cell cycle	biological_process	Any process that activates or increases the rate or extent of progression through the cell cycle.
GO:0045792	negative regulation of cell size	biological_process	Any process that reduces cell size.
GO:0045793	positive regulation of cell size	biological_process	Any process that increases cell size.
GO:0045794	negative regulation of cell volume	biological_process	Any process that decreases cell volume.
GO:0045795	positive regulation of cell volume	biological_process	Any process that increases cell volume.
GO:0045796	negative regulation of intestinal cholesterol absorption	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
GO:0045797	positive regulation of intestinal cholesterol absorption	biological_process	Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
GO:0045800	negative regulation of chitin-based cuticle tanning	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.
GO:0045801	positive regulation of chitin-based cuticle tanning	biological_process	Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning.
GO:0045804	negative regulation of eclosion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.
GO:0045805	positive regulation of eclosion	biological_process	Any process that activates or increases the frequency, rate or extent of eclosion.
GO:0045806	negative regulation of endocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
GO:0045807	positive regulation of endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of endocytosis.
GO:0045808	negative regulation of establishment of competence for transformation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.
GO:0045809	positive regulation of establishment of competence for transformation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation.
GO:0045812	negative regulation of Wnt signaling pathway, calcium modulating pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
GO:0045813	positive regulation of Wnt signaling pathway, calcium modulating pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
GO:0045814	negative regulation of gene expression, epigenetic	biological_process	An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation.
GO:0045815	transcription initiation-coupled chromatin remodeling	biological_process	An epigenetic mechanism of regulation of gene expression that involves chromatin remodeling to capacitate gene expression by either modifying the chromatin fiber, the nucleosomal histones, or the DNA.
GO:0045818	negative regulation of glycogen catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
GO:0045819	positive regulation of glycogen catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
GO:0045820	negative regulation of glycolytic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.
GO:0045821	positive regulation of glycolytic process	biological_process	Any process that activates or increases the frequency, rate or extent of glycolysis.
GO:0045822	negative regulation of heart contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
GO:0045823	positive regulation of heart contraction	biological_process	Any process that activates or increases the frequency, rate or extent of heart contraction.
GO:0045824	negative regulation of innate immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
GO:0045827	negative regulation of isoprenoid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
GO:0045828	positive regulation of isoprenoid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
GO:0045829	negative regulation of isotype switching	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.
GO:0045830	positive regulation of isotype switching	biological_process	Any process that activates or increases the frequency, rate or extent of isotype switching.
GO:0045831	negative regulation of light-activated channel activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity.
GO:0045832	positive regulation of light-activated channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of light-activated channel activity.
GO:0045833	negative regulation of lipid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GO:0045834	positive regulation of lipid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GO:0045835	negative regulation of meiotic nuclear division	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
GO:0045836	positive regulation of meiotic nuclear division	biological_process	Any process that activates or increases the frequency, rate or extent of meiosis.
GO:0045837	negative regulation of membrane potential	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0045838	positive regulation of membrane potential	biological_process	Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0045839	negative regulation of mitotic nuclear division	biological_process	Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
GO:0045840	positive regulation of mitotic nuclear division	biological_process	Any process that activates or increases the frequency, rate or extent of mitosis.
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	biological_process	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
GO:0045843	negative regulation of striated muscle tissue development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.
GO:0045844	positive regulation of striated muscle tissue development	biological_process	Any process that activates or increases the frequency, rate or extent of striated muscle development.
GO:0045847	negative regulation of nitrogen utilization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization.
GO:0045848	positive regulation of nitrogen utilization	biological_process	Any process that activates or increases the frequency, rate or extent of nitrogen utilization.
GO:0045849	negative regulation of nurse cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process.
GO:0045850	positive regulation of nurse cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.
GO:0045851	pH reduction	biological_process	Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
GO:0045852	pH elevation	biological_process	Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
GO:0045853	negative regulation of bicoid mRNA localization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
GO:0045854	positive regulation of bicoid mRNA localization	biological_process	Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
GO:0045855	negative regulation of pole plasm oskar mRNA localization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
GO:0045856	positive regulation of pole plasm oskar mRNA localization	biological_process	Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
GO:0045859	regulation of protein kinase activity	biological_process	Any process that modulates the frequency, rate or extent of protein kinase activity.
GO:0045860	positive regulation of protein kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of protein kinase activity.
GO:0045861	negative regulation of proteolysis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GO:0045862	positive regulation of proteolysis	biological_process	Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GO:0045863	negative regulation of pteridine metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
GO:0045864	positive regulation of pteridine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
GO:0045870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	biological_process	Any process that activates or increases the frequency, rate or extent of retroviral genome replication.
GO:0045873	negative regulation of sevenless signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.
GO:0045874	positive regulation of sevenless signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.
GO:0045875	negative regulation of sister chromatid cohesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.
GO:0045876	positive regulation of sister chromatid cohesion	biological_process	Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.
GO:0045879	negative regulation of smoothened signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
GO:0045880	positive regulation of smoothened signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of smoothened signaling.
GO:0045881	positive regulation of sporulation resulting in formation of a cellular spore	biological_process	Any process that activates or increases the frequency, rate or extent of sporulation.
GO:0045882	negative regulation of sulfur utilization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.
GO:0045883	positive regulation of sulfur utilization	biological_process	Any process that activates or increases the frequency, rate or extent of sulfur utilization.
GO:0045886	negative regulation of synaptic assembly at neuromuscular junction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction.
GO:0045887	positive regulation of synaptic assembly at neuromuscular junction	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction.
GO:0045892	negative regulation of DNA-templated transcription	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0045893	positive regulation of DNA-templated transcription	biological_process	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GO:0045894	negative regulation of mating-type specific transcription, DNA-templated	biological_process	Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.
GO:0045895	positive regulation of mating-type specific transcription, DNA-templated	biological_process	Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	biological_process	Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
GO:0045900	negative regulation of translational elongation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.
GO:0045901	positive regulation of translational elongation	biological_process	Any process that activates or increases the frequency, rate or extent of translational elongation.
GO:0045902	negative regulation of translational fidelity	biological_process	Any process that decreases the ability of the translational apparatus to interpret the genetic code.
GO:0045903	positive regulation of translational fidelity	biological_process	Any process that increases the ability of the translational apparatus to interpret the genetic code.
GO:0045904	negative regulation of translational termination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.
GO:0045905	positive regulation of translational termination	biological_process	Any process that activates or increases the frequency, rate or extent of translational termination.
GO:0045906	negative regulation of vasoconstriction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.
GO:0045907	positive regulation of vasoconstriction	biological_process	Any process that activates or increases the frequency, rate or extent of vasoconstriction.
GO:0045910	negative regulation of DNA recombination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
GO:0045911	positive regulation of DNA recombination	biological_process	Any process that activates or increases the frequency, rate or extent of DNA recombination.
GO:0045912	negative regulation of carbohydrate metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GO:0045913	positive regulation of carbohydrate metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GO:0045914	negative regulation of catecholamine metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.
GO:0045915	positive regulation of catecholamine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.
GO:0045916	negative regulation of complement activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.
GO:0045917	positive regulation of complement activation	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation.
GO:0045918	negative regulation of cytolysis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis.
GO:0045919	positive regulation of cytolysis	biological_process	Any process that activates or increases the frequency, rate or extent of cytolysis.
GO:0045920	negative regulation of exocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
GO:0045921	positive regulation of exocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of exocytosis.
GO:0045922	negative regulation of fatty acid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
GO:0045923	positive regulation of fatty acid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
GO:0045924	regulation of female receptivity	biological_process	Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.
GO:0045925	positive regulation of female receptivity	biological_process	Any process that activates or increases the receptiveness of a female to male advances.
GO:0045926	negative regulation of growth	biological_process	Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
GO:0045927	positive regulation of growth	biological_process	Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
GO:0045928	negative regulation of juvenile hormone metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
GO:0045929	positive regulation of juvenile hormone metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
GO:0045930	negative regulation of mitotic cell cycle	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
GO:0045931	positive regulation of mitotic cell cycle	biological_process	Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
GO:0045932	negative regulation of muscle contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.
GO:0045933	positive regulation of muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of muscle contraction.
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	biological_process	Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	biological_process	Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0045936	negative regulation of phosphate metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GO:0045937	positive regulation of phosphate metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	biological_process	Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
GO:0045939	negative regulation of steroid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.
GO:0045940	positive regulation of steroid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.
GO:0045942	negative regulation of phosphorus utilization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.
GO:0045943	positive regulation of transcription by RNA polymerase I	biological_process	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.
GO:0045944	positive regulation of transcription by RNA polymerase II	biological_process	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0045945	positive regulation of transcription by RNA polymerase III	biological_process	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.
GO:0045947	negative regulation of translational initiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
GO:0045948	positive regulation of translational initiation	biological_process	Any process that activates or increases the frequency, rate or extent of translational initiation.
GO:0045949	positive regulation of phosphorus utilization	biological_process	Any process that activates or increases the frequency, rate or extent of phosphorus utilization.
GO:0045950	negative regulation of mitotic recombination	biological_process	Any process that inhibits or decreases the rate of DNA recombination during mitosis.
GO:0045951	positive regulation of mitotic recombination	biological_process	Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.
GO:0045952	regulation of juvenile hormone catabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	biological_process	Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
GO:0045955	negative regulation of calcium ion-dependent exocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.
GO:0045956	positive regulation of calcium ion-dependent exocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.
GO:0045957	negative regulation of complement activation, alternative pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
GO:0045958	positive regulation of complement activation, alternative pathway	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.
GO:0045959	negative regulation of complement activation, classical pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
GO:0045960	positive regulation of complement activation, classical pathway	biological_process	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.
GO:0045961	negative regulation of development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.
GO:0045962	positive regulation of development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.
GO:0045963	negative regulation of dopamine metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
GO:0045964	positive regulation of dopamine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
GO:0045965	negative regulation of ecdysteroid metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.
GO:0045966	positive regulation of ecdysteroid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.
GO:0045967	negative regulation of growth rate	biological_process	Any process that reduces the rate of growth of all or part of an organism.
GO:0045968	negative regulation of juvenile hormone biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
GO:0045969	positive regulation of juvenile hormone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
GO:0045970	negative regulation of juvenile hormone catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
GO:0045971	positive regulation of juvenile hormone catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
GO:0045972	negative regulation of juvenile hormone secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.
GO:0045973	positive regulation of juvenile hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.
GO:0045974	regulation of translation, ncRNA-mediated	biological_process	Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.
GO:0045975	positive regulation of translation, ncRNA-mediated	biological_process	Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein.
GO:0045976	negative regulation of mitotic cell cycle, embryonic	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle.
GO:0045977	positive regulation of mitotic cell cycle, embryonic	biological_process	Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.
GO:0045978	negative regulation of nucleoside metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GO:0045979	positive regulation of nucleoside metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
GO:0045980	negative regulation of nucleotide metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GO:0045981	positive regulation of nucleotide metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GO:0045982	negative regulation of purine nucleobase metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.
GO:0045983	positive regulation of purine nucleobase metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.
GO:0045984	negative regulation of pyrimidine nucleobase metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
GO:0045985	positive regulation of pyrimidine nucleobase metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
GO:0045986	negative regulation of smooth muscle contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.
GO:0045987	positive regulation of smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
GO:0045988	negative regulation of striated muscle contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.
GO:0045989	positive regulation of striated muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of striated muscle contraction.
GO:0045990	carbon catabolite regulation of transcription	biological_process	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.
GO:0045991	carbon catabolite activation of transcription	biological_process	A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.
GO:0045992	negative regulation of embryonic development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
GO:0045993	negative regulation of translational initiation by iron	biological_process	Any process involving iron that stops, prevents or reduces the rate of translational initiation.
GO:0045994	positive regulation of translational initiation by iron	biological_process	Any process involving iron that activates or increases the rate of translational initiation.
GO:0045995	regulation of embryonic development	biological_process	Any process that modulates the frequency, rate or extent of embryonic development.
GO:0045997	negative regulation of ecdysteroid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
GO:0045998	positive regulation of ecdysteroid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
GO:0045999	negative regulation of ecdysteroid secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.
GO:0046000	positive regulation of ecdysteroid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.
GO:0046001	negative regulation of preblastoderm mitotic cell cycle	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle.
GO:0046002	positive regulation of preblastoderm mitotic cell cycle	biological_process	Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.
GO:0046003	negative regulation of syncytial blastoderm mitotic cell cycle	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.
GO:0046004	positive regulation of syncytial blastoderm mitotic cell cycle	biological_process	Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	biological_process	Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.
GO:0046006	regulation of activated T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of activated T cell proliferation.
GO:0046007	negative regulation of activated T cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
GO:0046008	regulation of female receptivity, post-mating	biological_process	Any process that modulates the receptiveness of a female to male advances subsequent to mating.
GO:0046009	positive regulation of female receptivity, post-mating	biological_process	Any process that increases the receptiveness of a female to male advances subsequent to mating.
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	biological_process	Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.
GO:0046011	regulation of oskar mRNA translation	biological_process	Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.
GO:0046012	positive regulation of oskar mRNA translation	biological_process	Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.
GO:0046013	regulation of T cell homeostatic proliferation	biological_process	Any process that modulates the frequency, rate or extent of resting T cell proliferation.
GO:0046014	negative regulation of T cell homeostatic proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.
GO:0046015	regulation of transcription by glucose	biological_process	Any process involving glucose that modulates the frequency, rate or extent or transcription.
GO:0046016	positive regulation of transcription by glucose	biological_process	Any process involving glucose that activates or increases the rate of transcription.
GO:0046025	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.
GO:0046026	precorrin-4 C11-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.
GO:0046027	phospholipid:diacylglycerol acyltransferase activity	molecular_function	Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.
GO:0046028	electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity	molecular_function	Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II.
GO:0046029	mannitol dehydrogenase activity	molecular_function	Catalysis of the reaction: D-mannitol + NAD+ = D-mannose + H+ + NADH.
GO:0046030	inositol trisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.
GO:0046031	ADP metabolic process	biological_process	The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.
GO:0046032	ADP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.
GO:0046033	AMP metabolic process	biological_process	The chemical reactions and pathways involving AMP, adenosine monophosphate.
GO:0046034	ATP metabolic process	biological_process	The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
GO:0046035	CMP metabolic process	biological_process	The chemical reactions and pathways involving CMP, cytidine monophosphate.
GO:0046036	CTP metabolic process	biological_process	The chemical reactions and pathways involving CTP, cytidine triphosphate.
GO:0046037	GMP metabolic process	biological_process	The chemical reactions and pathways involving GMP, guanosine monophosphate.
GO:0046038	GMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.
GO:0046039	GTP metabolic process	biological_process	The chemical reactions and pathways involving GTP, guanosine triphosphate.
GO:0046040	IMP metabolic process	biological_process	The chemical reactions and pathways involving IMP, inosine monophosphate.
GO:0046041	ITP metabolic process	biological_process	The chemical reactions and pathways involving ITP, inosine triphosphate.
GO:0046042	ITP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate.
GO:0046043	TDP metabolic process	biological_process	The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.
GO:0046044	TMP metabolic process	biological_process	The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.
GO:0046045	TMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.
GO:0046046	TTP metabolic process	biological_process	The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.
GO:0046047	TTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.
GO:0046048	UDP metabolic process	biological_process	The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.
GO:0046049	UMP metabolic process	biological_process	The chemical reactions and pathways involving UMP, uridine monophosphate.
GO:0046050	UMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.
GO:0046051	UTP metabolic process	biological_process	The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.
GO:0046052	UTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.
GO:0046053	dAMP metabolic process	biological_process	The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
GO:0046054	dGMP metabolic process	biological_process	The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
GO:0046055	dGMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
GO:0046056	dADP metabolic process	biological_process	The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
GO:0046057	dADP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
GO:0046058	cAMP metabolic process	biological_process	The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
GO:0046059	dAMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
GO:0046060	dATP metabolic process	biological_process	The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
GO:0046061	dATP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
GO:0046062	dCDP metabolic process	biological_process	The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.
GO:0046063	dCMP metabolic process	biological_process	The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.
GO:0046064	dCMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.
GO:0046065	dCTP metabolic process	biological_process	The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.
GO:0046066	dGDP metabolic process	biological_process	The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
GO:0046067	dGDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
GO:0046068	cGMP metabolic process	biological_process	The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
GO:0046069	cGMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.
GO:0046070	dGTP metabolic process	biological_process	The chemical reactions and pathways involving dGTP, guanosine triphosphate.
GO:0046071	dGTP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate.
GO:0046072	dTDP metabolic process	biological_process	The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate.
GO:0046073	dTMP metabolic process	biological_process	The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
GO:0046074	dTMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.
GO:0046075	dTTP metabolic process	biological_process	The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.
GO:0046076	dTTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.
GO:0046077	dUDP metabolic process	biological_process	The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.
GO:0046078	dUMP metabolic process	biological_process	The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate).
GO:0046079	dUMP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate.
GO:0046080	dUTP metabolic process	biological_process	The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.
GO:0046081	dUTP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.
GO:0046082	5-methylcytosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.
GO:0046083	adenine metabolic process	biological_process	The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
GO:0046084	adenine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
GO:0046085	adenosine metabolic process	biological_process	The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
GO:0046086	adenosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
GO:0046087	cytidine metabolic process	biological_process	The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside.
GO:0046088	cytidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.
GO:0046089	cytosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
GO:0046090	deoxyadenosine metabolic process	biological_process	The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
GO:0046091	deoxyadenosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
GO:0046092	deoxycytidine metabolic process	biological_process	The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
GO:0046093	deoxycytidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
GO:0046094	deoxyinosine metabolic process	biological_process	The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.
GO:0046095	deoxyinosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside.
GO:0046096	deoxyuridine metabolic process	biological_process	The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
GO:0046097	deoxyuridine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
GO:0046098	guanine metabolic process	biological_process	The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
GO:0046099	guanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
GO:0046100	hypoxanthine metabolic process	biological_process	The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
GO:0046101	hypoxanthine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
GO:0046102	inosine metabolic process	biological_process	The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
GO:0046103	inosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
GO:0046104	thymidine metabolic process	biological_process	The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
GO:0046105	thymidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
GO:0046106	thymine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
GO:0046107	uracil biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
GO:0046108	uridine metabolic process	biological_process	The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
GO:0046109	uridine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
GO:0046110	xanthine metabolic process	biological_process	The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
GO:0046111	xanthine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
GO:0046112	nucleobase biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
GO:0046113	nucleobase catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
GO:0046114	guanosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.
GO:0046115	guanosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution.
GO:0046116	queuosine metabolic process	biological_process	The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
GO:0046117	queuosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
GO:0046118	7-methylguanosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
GO:0046119	7-methylguanosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
GO:0046120	deoxyribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046121	deoxyribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046122	purine deoxyribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046123	purine deoxyribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046124	purine deoxyribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046126	pyrimidine deoxyribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046127	pyrimidine deoxyribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
GO:0046128	purine ribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046129	purine ribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046130	purine ribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046131	pyrimidine ribonucleoside metabolic process	biological_process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046132	pyrimidine ribonucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046133	pyrimidine ribonucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
GO:0046134	pyrimidine nucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0046135	pyrimidine nucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
GO:0046136	positive regulation of vitamin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0046137	negative regulation of vitamin metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0046140	corrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
GO:0046141	corrin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
GO:0046146	tetrahydrobiopterin metabolic process	biological_process	The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
GO:0046147	tetrahydrobiopterin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
GO:0046148	pigment biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
GO:0046149	pigment catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
GO:0046150	melanin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
GO:0046151	eye pigment catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
GO:0046152	ommochrome metabolic process	biological_process	The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
GO:0046153	ommochrome catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
GO:0046154	rhodopsin metabolic process	biological_process	The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
GO:0046155	rhodopsin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
GO:0046156	siroheme metabolic process	biological_process	The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
GO:0046157	siroheme catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
GO:0046158	ocellus pigment metabolic process	biological_process	The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
GO:0046159	ocellus pigment catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
GO:0046160	heme a metabolic process	biological_process	The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.
GO:0046161	heme a catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.
GO:0046162	heme C metabolic process	biological_process	The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.
GO:0046163	heme C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f.
GO:0046164	alcohol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
GO:0046165	alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
GO:0046166	glyceraldehyde-3-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
GO:0046167	glycerol-3-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
GO:0046168	glycerol-3-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
GO:0046169	methanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
GO:0046170	methanol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
GO:0046171	octanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.
GO:0046172	octanol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.
GO:0046173	polyol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
GO:0046174	polyol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
GO:0046175	aldonic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
GO:0046176	aldonic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
GO:0046177	D-gluconate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
GO:0046178	D-gluconate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
GO:0046179	keto-D-gluconate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
GO:0046180	ketogluconate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
GO:0046181	ketogluconate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
GO:0046182	L-idonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
GO:0046183	L-idonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
GO:0046184	aldehyde biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.
GO:0046185	aldehyde catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.
GO:0046186	acetaldehyde biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
GO:0046187	acetaldehyde catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
GO:0046188	methane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
GO:0046189	phenol-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
GO:0046190	aerobic phenol-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
GO:0046191	aerobic phenol-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
GO:0046192	anaerobic phenol-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
GO:0046193	anaerobic phenol-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
GO:0046196	4-nitrophenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
GO:0046197	orcinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.
GO:0046199	cresol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.
GO:0046201	cyanate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid.
GO:0046202	cyanide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.
GO:0046203	spermidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0046204	nor-spermidine metabolic process	biological_process	The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0046205	nor-spermidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
GO:0046206	trypanothione metabolic process	biological_process	The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
GO:0046207	trypanothione catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
GO:0046208	spermine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
GO:0046209	nitric oxide metabolic process	biological_process	The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
GO:0046210	nitric oxide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
GO:0046211	(+)-camphor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone.
GO:0046213	methyl ethyl ketone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor.
GO:0046214	enterobactin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
GO:0046215	siderophore catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
GO:0046216	indole phytoalexin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.
GO:0046217	indole phytoalexin metabolic process	biological_process	The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response.
GO:0046219	indolalkylamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
GO:0046220	pyridine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
GO:0046221	pyridine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
GO:0046222	aflatoxin metabolic process	biological_process	The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
GO:0046223	aflatoxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
GO:0046224	bacteriocin metabolic process	biological_process	The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
GO:0046225	bacteriocin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
GO:0046226	coumarin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
GO:0046228	2,4,5-trichlorophenoxyacetic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
GO:0046230	2-aminobenzenesulfonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
GO:0046232	carbazole catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
GO:0046236	mandelate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
GO:0046239	phthalate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid.
GO:0046244	salicylic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
GO:0046246	terpene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.
GO:0046247	terpene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.
GO:0046248	alpha-pinene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.
GO:0046249	alpha-pinene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.
GO:0046250	limonene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
GO:0046251	limonene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
GO:0046252	toluene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.
GO:0046253	anaerobic toluene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.
GO:0046254	anaerobic toluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.
GO:0046256	2,4,6-trinitrotoluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.
GO:0046258	anaerobic 2,4,6-trinitrotoluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.
GO:0046260	trinitrotoluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.
GO:0046263	nitrotoluene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.
GO:0046265	thiocyanate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.
GO:0046269	toluene-4-sulfonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.
GO:0046271	phenylpropanoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid.
GO:0046272	stilbene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.
GO:0046273	lignan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
GO:0046274	lignin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.
GO:0046275	flavonoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
GO:0046276	methylgallate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
GO:0046277	methylgallate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
GO:0046278	3,4-dihydroxybenzoate metabolic process	biological_process	The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).
GO:0046279	3,4-dihydroxybenzoate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.
GO:0046280	chalcone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.
GO:0046281	cinnamic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.
GO:0046282	cinnamic acid ester catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.
GO:0046283	anthocyanin-containing compound metabolic process	biological_process	The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.
GO:0046284	anthocyanin-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.
GO:0046285	flavonoid phytoalexin metabolic process	biological_process	The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0046286	flavonoid phytoalexin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0046287	isoflavonoid metabolic process	biological_process	The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.
GO:0046288	isoflavonoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
GO:0046289	isoflavonoid phytoalexin metabolic process	biological_process	The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0046290	isoflavonoid phytoalexin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
GO:0046292	formaldehyde metabolic process	biological_process	The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
GO:0046293	formaldehyde biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.
GO:0046294	formaldehyde catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
GO:0046295	glycolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
GO:0046296	glycolate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
GO:0046298	2,4-dichlorobenzoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
GO:0046300	2,4-dichlorophenoxyacetic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
GO:0046302	2-chloro-N-isopropylacetanilide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.
GO:0046304	2-nitropropane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.
GO:0046305	alkanesulfonate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
GO:0046306	alkanesulfonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
GO:0046307	Z-phenylacetaldoxime biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.
GO:0046308	Z-phenylacetaldoxime catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.
GO:0046311	prenylcysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
GO:0046312	phosphoarginine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine.
GO:0046313	phosphoarginine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine.
GO:0046314	phosphocreatine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.
GO:0046315	phosphocreatine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.
GO:0046316	gluconokinase activity	molecular_function	Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H+.
GO:0046317	regulation of glucosylceramide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
GO:0046318	negative regulation of glucosylceramide biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
GO:0046319	positive regulation of glucosylceramide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
GO:0046320	regulation of fatty acid oxidation	biological_process	Any process that modulates the frequency, rate or extent of fatty acid oxidation.
GO:0046321	positive regulation of fatty acid oxidation	biological_process	Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.
GO:0046322	negative regulation of fatty acid oxidation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
GO:0046323	glucose import	biological_process	The directed movement of the hexose monosaccharide glucose into a cell or organelle.
GO:0046324	regulation of glucose import	biological_process	Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
GO:0046325	negative regulation of glucose import	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
GO:0046326	positive regulation of glucose import	biological_process	Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
GO:0046327	glycerol biosynthetic process from pyruvate	biological_process	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate.
GO:0046328	regulation of JNK cascade	biological_process	Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
GO:0046329	negative regulation of JNK cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
GO:0046330	positive regulation of JNK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
GO:0046331	lateral inhibition	biological_process	Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
GO:0046332	SMAD binding	molecular_function	Binding to a SMAD signaling protein.
GO:0046333	octopamine metabolic process	biological_process	The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
GO:0046334	octopamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
GO:0046335	ethanolamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
GO:0046336	ethanolamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
GO:0046337	phosphatidylethanolamine metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.
GO:0046338	phosphatidylethanolamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
GO:0046339	diacylglycerol metabolic process	biological_process	The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
GO:0046340	diacylglycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
GO:0046341	CDP-diacylglycerol metabolic process	biological_process	The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.
GO:0046342	CDP-diacylglycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
GO:0046343	streptomycin metabolic process	biological_process	The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
GO:0046344	ecdysteroid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
GO:0046345	abscisic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
GO:0046346	mannosamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
GO:0046347	mannosamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
GO:0046348	amino sugar catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.
GO:0046349	amino sugar biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.
GO:0046350	galactosaminoglycan metabolic process	biological_process	The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose.
GO:0046351	disaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.
GO:0046352	disaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.
GO:0046353	aminoglycoside 3-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
GO:0046354	mannan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.
GO:0046355	mannan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.
GO:0046356	acetyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
GO:0046357	galactarate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.
GO:0046358	butyrate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.
GO:0046359	butyrate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.
GO:0046360	2-oxobutyrate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
GO:0046361	2-oxobutyrate metabolic process	biological_process	The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
GO:0046362	ribitol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
GO:0046363	ribitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
GO:0046364	monosaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
GO:0046365	monosaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
GO:0046366	allose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
GO:0046367	allose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
GO:0046368	GDP-L-fucose metabolic process	biological_process	The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
GO:0046369	galactose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.
GO:0046370	fructose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.
GO:0046371	dTDP-mannose metabolic process	biological_process	The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.
GO:0046372	D-arabinose metabolic process	biological_process	The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides.
GO:0046373	L-arabinose metabolic process	biological_process	The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.
GO:0046374	teichoic acid metabolic process	biological_process	The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
GO:0046375	K antigen metabolic process	biological_process	The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.
GO:0046376	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process	biological_process	The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.
GO:0046377	colanic acid metabolic process	biological_process	The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.
GO:0046378	enterobacterial common antigen metabolic process	biological_process	The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
GO:0046379	extracellular polysaccharide metabolic process	biological_process	The chemical reactions and pathways involving polysaccharides used in extracellular structures.
GO:0046380	N-acetylneuraminate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
GO:0046381	CMP-N-acetylneuraminate metabolic process	biological_process	The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.
GO:0046382	GDP-D-rhamnose metabolic process	biological_process	The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
GO:0046383	dTDP-rhamnose metabolic process	biological_process	The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
GO:0046384	2-deoxyribose 1-phosphate metabolic process	biological_process	The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
GO:0046385	deoxyribose phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
GO:0046386	deoxyribose phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
GO:0046387	deoxyribose 1,5-bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.
GO:0046389	deoxyribose 5-phosphate metabolic process	biological_process	The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose.
GO:0046390	ribose phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.
GO:0046391	5-phosphoribose 1-diphosphate metabolic process	biological_process	The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
GO:0046392	galactarate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.
GO:0046394	carboxylic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
GO:0046395	carboxylic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
GO:0046396	D-galacturonate metabolic process	biological_process	The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.
GO:0046397	galacturonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.
GO:0046398	UDP-glucuronate metabolic process	biological_process	The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
GO:0046399	glucuronate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.
GO:0046400	keto-3-deoxy-D-manno-octulosonic acid metabolic process	biological_process	The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.
GO:0046401	lipopolysaccharide core region metabolic process	biological_process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.
GO:0046402	O antigen metabolic process	biological_process	The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
GO:0046403	polynucleotide 3'-phosphatase activity	molecular_function	Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.
GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.
GO:0046405	glycerol dehydratase activity	molecular_function	Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O.
GO:0046406	magnesium protoporphyrin IX methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H+ + magnesium protoporphyrin IX 13-monomethyl ester.
GO:0046408	chlorophyll synthetase activity	molecular_function	Catalysis of the reaction: chlorophyllide a + 2 H+ + phytyl diphosphate = chlorophyll a + diphosphate.
GO:0046409	p-coumarate 3-hydroxylase activity	molecular_function	Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.
GO:0046411	2-keto-3-deoxygluconate transmembrane transport	biological_process	The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0046412	phenylmercury acetate metabolic process	biological_process	The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.
GO:0046413	organomercury catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom.
GO:0046414	organomercury biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.
GO:0046415	urate metabolic process	biological_process	The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
GO:0046416	D-amino acid metabolic process	biological_process	The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.
GO:0046417	chorismate metabolic process	biological_process	The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.
GO:0046418	nopaline metabolic process	biological_process	The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.
GO:0046419	octopine metabolic process	biological_process	The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.
GO:0046421	methylisocitrate lyase activity	molecular_function	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
GO:0046422	violaxanthin de-epoxidase activity	molecular_function	Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.
GO:0046423	allene-oxide cyclase activity	molecular_function	Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.
GO:0046424	ferulate 5-hydroxylase activity	molecular_function	Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	biological_process	Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	biological_process	Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
GO:0046428	1,4-dihydroxy-2-naphthoate octaprenyltransferase activity	molecular_function	Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.
GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	molecular_function	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.
GO:0046430	non-phosphorylated glucose metabolic process	biological_process	The chemical reactions and pathways involving non-phosphorylated forms of glucose.
GO:0046431	(R)-4-hydroxymandelate metabolic process	biological_process	The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).
GO:0046432	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process	biological_process	The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
GO:0046433	2-aminoethylphosphonate metabolic process	biological_process	The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms.
GO:0046434	organophosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.
GO:0046435	3-(3-hydroxy)phenylpropionate metabolic process	biological_process	The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.
GO:0046436	D-alanine metabolic process	biological_process	The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.
GO:0046437	D-amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.
GO:0046438	D-cysteine metabolic process	biological_process	The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.
GO:0046439	L-cysteine metabolic process	biological_process	The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.
GO:0046440	L-lysine metabolic process	biological_process	The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid.
GO:0046441	D-lysine metabolic process	biological_process	The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.
GO:0046442	aerobactin metabolic process	biological_process	The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
GO:0046443	FAD metabolic process	biological_process	The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.
GO:0046444	FMN metabolic process	biological_process	The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
GO:0046445	benzyl isoquinoline alkaloid metabolic process	biological_process	The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.
GO:0046446	purine alkaloid metabolic process	biological_process	The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.
GO:0046447	terpenoid indole alkaloid metabolic process	biological_process	The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).
GO:0046448	tropane alkaloid metabolic process	biological_process	The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.
GO:0046449	creatinine metabolic process	biological_process	The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.
GO:0046450	dethiobiotin metabolic process	biological_process	The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.
GO:0046451	diaminopimelate metabolic process	biological_process	The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
GO:0046452	dihydrofolate metabolic process	biological_process	The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.
GO:0046453	dipyrrin metabolic process	biological_process	The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.
GO:0046454	dimethylsilanediol metabolic process	biological_process	The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.
GO:0046455	organosilicon catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.
GO:0046456	icosanoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
GO:0046457	prostanoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.
GO:0046458	hexadecanal metabolic process	biological_process	The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
GO:0046459	short-chain fatty acid metabolic process	biological_process	The chemical reactions and pathways involving a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0046460	neutral lipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.
GO:0046461	neutral lipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.
GO:0046462	monoacylglycerol metabolic process	biological_process	The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
GO:0046463	acylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
GO:0046464	acylglycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
GO:0046465	dolichyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.
GO:0046466	membrane lipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
GO:0046467	membrane lipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.
GO:0046468	phosphatidyl-N-monomethylethanolamine metabolic process	biological_process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.
GO:0046469	platelet activating factor metabolic process	biological_process	The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
GO:0046470	phosphatidylcholine metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
GO:0046471	phosphatidylglycerol metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
GO:0046473	phosphatidic acid metabolic process	biological_process	The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
GO:0046474	glycerophospholipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
GO:0046475	glycerophospholipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
GO:0046476	glycosylceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
GO:0046477	glycosylceramide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
GO:0046478	lactosylceramide metabolic process	biological_process	The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
GO:0046479	glycosphingolipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
GO:0046480	galactolipid galactosyltransferase activity	molecular_function	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol.
GO:0046481	digalactosyldiacylglycerol synthase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H+ + UDP.
GO:0046482	para-aminobenzoic acid metabolic process	biological_process	The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.
GO:0046483	heterocycle metabolic process	biological_process	The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0046484	oxazole or thiazole metabolic process	biological_process	The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.
GO:0046485	ether lipid metabolic process	biological_process	The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
GO:0046486	glycerolipid metabolic process	biological_process	The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
GO:0046487	glyoxylate metabolic process	biological_process	The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
GO:0046488	phosphatidylinositol metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
GO:0046490	isopentenyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
GO:0046491	L-methylmalonyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.
GO:0046492	heme B metabolic process	biological_process	The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
GO:0046493	lipid A metabolic process	biological_process	The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.
GO:0046494	rhizobactin 1021 metabolic process	biological_process	The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.
GO:0046495	nicotinamide riboside metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
GO:0046496	nicotinamide nucleotide metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
GO:0046497	nicotinate nucleotide metabolic process	biological_process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin).
GO:0046498	S-adenosylhomocysteine metabolic process	biological_process	The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
GO:0046499	S-adenosylmethioninamine metabolic process	biological_process	The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.
GO:0046500	S-adenosylmethionine metabolic process	biological_process	The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
GO:0046501	protoporphyrinogen IX metabolic process	biological_process	The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
GO:0046502	uroporphyrinogen III metabolic process	biological_process	The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.
GO:0046503	glycerolipid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.
GO:0046504	glycerol ether biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
GO:0046505	sulfolipid metabolic process	biological_process	The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.
GO:0046506	sulfolipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.
GO:0046507	UDPsulfoquinovose synthase activity	molecular_function	Catalysis of the reaction: sulfite + UDP-D-glucose = H2O + UDP-6-sulfoquinovose.
GO:0046508	hydrolase activity, acting on carbon-sulfur bonds	molecular_function	Catalysis of the hydrolysis of any carbon-sulfur bond, C-S.
GO:0046509	1,2-diacylglycerol 3-beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H+ + UDP.
GO:0046510	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.
GO:0046511	sphinganine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.
GO:0046512	sphingosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
GO:0046513	ceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
GO:0046514	ceramide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.
GO:0046516	hypusine metabolic process	biological_process	The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
GO:0046517	octamethylcyclotetrasiloxane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.
GO:0046518	octamethylcyclotetrasiloxane metabolic process	biological_process	The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.
GO:0046519	sphingoid metabolic process	biological_process	The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
GO:0046520	sphingoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
GO:0046521	sphingoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
GO:0046522	S-methyl-5-thioribose kinase activity	molecular_function	Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H+.
GO:0046523	S-methyl-5-thioribose-1-phosphate isomerase activity	molecular_function	Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.
GO:0046524	sucrose-phosphate synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.
GO:0046525	xylosylprotein 4-beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.
GO:0046526	D-xylulose reductase activity	molecular_function	Catalysis of the reaction: NAD+ + xylitol = D-xylulose + H+ + NADH.
GO:0046527	glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0046528	imaginal disc fusion	biological_process	The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.
GO:0046529	imaginal disc fusion, thorax closure	biological_process	The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
GO:0046530	photoreceptor cell differentiation	biological_process	The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.
GO:0046532	regulation of photoreceptor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
GO:0046533	negative regulation of photoreceptor cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
GO:0046534	positive regulation of photoreceptor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
GO:0046535	detection of chemical stimulus involved in sensory perception of umami taste	biological_process	The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.
GO:0046536	dosage compensation complex	cellular_component	A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.
GO:0046537	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	molecular_function	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.
GO:0046538	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	molecular_function	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction mechanism uses 2,3-bisphosphoglycerate as a phosphate donor.
GO:0046539	histamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H+.
GO:0046540	U4/U6 x U5 tri-snRNP complex	cellular_component	A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs.
GO:0046541	saliva secretion	biological_process	The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.
GO:0046543	development of secondary female sexual characteristics	biological_process	The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.
GO:0046544	development of secondary male sexual characteristics	biological_process	The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.
GO:0046545	development of primary female sexual characteristics	biological_process	The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.
GO:0046546	development of primary male sexual characteristics	biological_process	The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.
GO:0046547	trans-aconitate 3-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine.
GO:0046548	retinal rod cell development	biological_process	Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.
GO:0046549	retinal cone cell development	biological_process	Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
GO:0046551	retinal cone cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.
GO:0046552	photoreceptor cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
GO:0046553	D-malate dehydrogenase (decarboxylating) activity	molecular_function	Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.
GO:0046554	malate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.
GO:0046555	acetylxylan esterase activity	molecular_function	Catalysis of the deacetylation of xylans and xylo-oligosaccharides.
GO:0046556	alpha-L-arabinofuranosidase activity	molecular_function	Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
GO:0046557	glucan endo-1,6-beta-glucosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.
GO:0046558	arabinan endo-1,5-alpha-L-arabinosidase activity	molecular_function	Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.
GO:0046559	alpha-glucuronidase activity	molecular_function	Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.
GO:0046562	glucose oxidase activity	molecular_function	Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.
GO:0046563	methanol oxidase activity	molecular_function	Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde.
GO:0046564	oxalate decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + oxalate = CO2 + formate.
GO:0046565	3-dehydroshikimate dehydratase activity	molecular_function	Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
GO:0046566	DOPA dioxygenase activity	molecular_function	Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.
GO:0046567	aphidicolan-16 beta-ol synthase activity	molecular_function	Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate.
GO:0046568	3-methylbutanol:NAD(P) oxidoreductase activity	molecular_function	Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.
GO:0046569	glyoxal oxidase activity	molecular_function	Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2.
GO:0046570	methylthioribulose 1-phosphate dehydratase activity	molecular_function	Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O.
GO:0046571	aspartate-2-keto-4-methylthiobutyrate transaminase activity	molecular_function	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate.
GO:0046572	versicolorin B synthase activity	molecular_function	Catalysis of the reaction: versiconal = versicolorin B + H2O.
GO:0046573	lactonohydrolase activity	molecular_function	Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.
GO:0046574	glycuronidase activity	molecular_function	Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.
GO:0046575	rhamnogalacturonan acetylesterase activity	molecular_function	Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.
GO:0046576	rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity	molecular_function	Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.
GO:0046577	long-chain-alcohol oxidase activity	molecular_function	Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.
GO:0046578	regulation of Ras protein signal transduction	biological_process	Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
GO:0046579	positive regulation of Ras protein signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.
GO:0046580	negative regulation of Ras protein signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
GO:0046581	intercellular canaliculus	cellular_component	An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.
GO:0046583	monoatomic cation efflux transmembrane transporter activity	molecular_function	Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.
GO:0046584	enniatin metabolic process	biological_process	The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.
GO:0046585	enniatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.
GO:0046586	regulation of calcium-dependent cell-cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.
GO:0046588	negative regulation of calcium-dependent cell-cell adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.
GO:0046589	ribonuclease T1 activity	molecular_function	Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.
GO:0046592	polyamine oxidase activity	molecular_function	Catalysis of the oxidative degradation or interconversion of polyamines.
GO:0046593	mandelonitrile lyase activity	molecular_function	Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde.
GO:0046594	maintenance of pole plasm mRNA location	biological_process	The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster.
GO:0046595	establishment of pole plasm mRNA localization	biological_process	Any process that results in the directed movement of mRNA to the oocyte pole plasm.
GO:0046596	regulation of viral entry into host cell	biological_process	Any process that modulates the frequency, rate or extent of the viral entry into the host cell.
GO:0046597	negative regulation of viral entry into host cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.
GO:0046598	positive regulation of viral entry into host cell	biological_process	Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.
GO:0046599	regulation of centriole replication	biological_process	Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
GO:0046600	negative regulation of centriole replication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.
GO:0046601	positive regulation of centriole replication	biological_process	Any process that activates or increases the frequency, rate or extent of centriole replication.
GO:0046602	regulation of mitotic centrosome separation	biological_process	Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.
GO:0046603	negative regulation of mitotic centrosome separation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.
GO:0046604	positive regulation of mitotic centrosome separation	biological_process	Any process that activates or increases the frequency, rate or extent of centrosome separation.
GO:0046605	regulation of centrosome cycle	biological_process	Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.
GO:0046606	negative regulation of centrosome cycle	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.
GO:0046607	positive regulation of centrosome cycle	biological_process	Any process that activates or increases the frequency, rate or extent of the centrosome cycle.
GO:0046608	carotenoid isomerase activity	molecular_function	Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.
GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	cellular_component	The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.
GO:0046611	lysosomal proton-transporting V-type ATPase complex	cellular_component	A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen.
GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	cellular_component	The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.
GO:0046618	xenobiotic export from cell	biological_process	The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0046619	lens placode formation involved in camera-type eye formation	biological_process	Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.
GO:0046620	regulation of organ growth	biological_process	Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
GO:0046621	negative regulation of organ growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
GO:0046622	positive regulation of organ growth	biological_process	Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
GO:0046623	sphingolipid floppase activity	molecular_function	Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0046624	sphingolipid transporter activity	molecular_function	Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0046625	sphingolipid binding	molecular_function	Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0046626	regulation of insulin receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of insulin receptor signaling.
GO:0046627	negative regulation of insulin receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
GO:0046628	positive regulation of insulin receptor signaling pathway	biological_process	Any process that increases the frequency, rate or extent of insulin receptor signaling.
GO:0046629	gamma-delta T cell activation	biological_process	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0046630	gamma-delta T cell proliferation	biological_process	The expansion of a gamma-delta T cell population by cell division.
GO:0046631	alpha-beta T cell activation	biological_process	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0046632	alpha-beta T cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
GO:0046633	alpha-beta T cell proliferation	biological_process	The expansion of an alpha-beta T cell population by cell division.
GO:0046634	regulation of alpha-beta T cell activation	biological_process	Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.
GO:0046635	positive regulation of alpha-beta T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.
GO:0046636	negative regulation of alpha-beta T cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.
GO:0046637	regulation of alpha-beta T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation.
GO:0046638	positive regulation of alpha-beta T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.
GO:0046639	negative regulation of alpha-beta T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
GO:0046640	regulation of alpha-beta T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.
GO:0046641	positive regulation of alpha-beta T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.
GO:0046642	negative regulation of alpha-beta T cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.
GO:0046643	regulation of gamma-delta T cell activation	biological_process	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation.
GO:0046644	negative regulation of gamma-delta T cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.
GO:0046645	positive regulation of gamma-delta T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.
GO:0046646	regulation of gamma-delta T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation.
GO:0046647	negative regulation of gamma-delta T cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.
GO:0046648	positive regulation of gamma-delta T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.
GO:0046649	lymphocyte activation	biological_process	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0046651	lymphocyte proliferation	biological_process	The expansion of a lymphocyte population by cell division.
GO:0046653	tetrahydrofolate metabolic process	biological_process	The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
GO:0046654	tetrahydrofolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
GO:0046655	folic acid metabolic process	biological_process	The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
GO:0046656	folic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.
GO:0046657	folic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.
GO:0046659	digestive hormone activity	molecular_function	The action characteristic of a hormone that takes part in the digestion process.
GO:0046660	female sex differentiation	biological_process	The establishment of the sex of a female organism by physical differentiation.
GO:0046661	male sex differentiation	biological_process	The establishment of the sex of a male organism by physical differentiation.
GO:0046662	regulation of egg-laying behavior	biological_process	Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
GO:0046663	dorsal closure, leading edge cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure.
GO:0046664	dorsal closure, amnioserosa morphology change	biological_process	The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.
GO:0046665	amnioserosa maintenance	biological_process	Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.
GO:0046666	retinal cell programmed cell death	biological_process	Programmed cell death that occurs in the developing retina.
GO:0046667	compound eye retinal cell programmed cell death	biological_process	Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.
GO:0046668	regulation of retinal cell programmed cell death	biological_process	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.
GO:0046669	regulation of compound eye retinal cell programmed cell death	biological_process	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
GO:0046670	positive regulation of retinal cell programmed cell death	biological_process	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.
GO:0046671	negative regulation of retinal cell programmed cell death	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.
GO:0046672	positive regulation of compound eye retinal cell programmed cell death	biological_process	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
GO:0046673	negative regulation of compound eye retinal cell programmed cell death	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
GO:0046676	negative regulation of insulin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
GO:0046677	response to antibiotic	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
GO:0046678	response to bacteriocin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
GO:0046679	response to streptomycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
GO:0046680	response to DDT	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.
GO:0046681	response to carbamate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.
GO:0046682	response to cyclodiene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring.
GO:0046683	response to organophosphorus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.
GO:0046684	response to pyrethroid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.
GO:0046685	response to arsenic-containing substance	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
GO:0046686	response to cadmium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
GO:0046687	response to chromate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
GO:0046688	response to copper ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
GO:0046689	response to mercury ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
GO:0046690	response to tellurium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.
GO:0046691	intracellular canaliculus	cellular_component	An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.
GO:0046692	sperm competition	biological_process	Any process that contributes to the success of sperm fertilization in multiply-mated females.
GO:0046693	sperm storage	biological_process	The retention of sperm by a female following mating.
GO:0046694	sperm incapacitation	biological_process	The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.
GO:0046695	SLIK (SAGA-like) complex	cellular_component	A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.
GO:0046696	lipopolysaccharide receptor complex	cellular_component	A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.
GO:0046697	decidualization	biological_process	The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
GO:0046700	heterocycle catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0046701	insecticide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects.
GO:0046702	galactoside 6-L-fucosyltransferase activity	molecular_function	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside.
GO:0046703	natural killer cell lectin-like receptor binding	molecular_function	Binding to a lectin-like natural killer cell receptor.
GO:0046704	CDP metabolic process	biological_process	The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.
GO:0046705	CDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.
GO:0046706	CDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.
GO:0046707	IDP metabolic process	biological_process	The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.
GO:0046708	IDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate.
GO:0046709	IDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.
GO:0046710	GDP metabolic process	biological_process	The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.
GO:0046711	GDP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.
GO:0046712	GDP catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.
GO:0046713	borate transport	biological_process	The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
GO:0046714	borate binding	molecular_function	Binding to borate, the anion (BO3)3-.
GO:0046715	active borate transmembrane transporter activity	molecular_function	Enables the transport of borate across a membrane against the concentration gradient.
GO:0046716	muscle cell cellular homeostasis	biological_process	The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
GO:0046717	acid secretion	biological_process	The controlled release of acid by a cell or a tissue.
GO:0046718	viral entry into host cell	biological_process	The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
GO:0046719	regulation by virus of viral protein levels in host cell	biological_process	Any virus-mediated process that modulates the levels of viral proteins in a cell.
GO:0046720	citric acid secretion	biological_process	The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue.
GO:0046721	formic acid secretion	biological_process	The controlled release of formic acid, HCOOH, by a cell or a tissue.
GO:0046722	lactic acid secretion	biological_process	The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue.
GO:0046723	malic acid secretion	biological_process	The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue.
GO:0046724	oxalic acid secretion	biological_process	The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.
GO:0046725	negative regulation by virus of viral protein levels in host cell	biological_process	Any process where the infecting virus reduces the levels of viral proteins in a cell.
GO:0046726	positive regulation by virus of viral protein levels in host cell	biological_process	Any process where the infecting virus increases the levels of viral proteins in a cell.
GO:0046727	capsomere	cellular_component	Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.
GO:0046729	viral procapsid	cellular_component	A stable empty viral capsid produced during the assembly of viruses.
GO:0046739	transport of virus in multicellular host	biological_process	The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).
GO:0046740	transport of virus in host, cell to cell	biological_process	The transport of a virus between adjacent cells in a multicellular organism.
GO:0046741	transport of virus in host, tissue to tissue	biological_process	The transport of a virus between tissues in a multicellular organism.
GO:0046745	viral capsid secondary envelopment	biological_process	The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.
GO:0046753	non-lytic viral release	biological_process	The exit of a viral particle from a host cell that does not involve cell lysis.
GO:0046754	viral exocytosis	biological_process	The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle.
GO:0046755	viral budding	biological_process	A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
GO:0046760	viral budding from Golgi membrane	biological_process	A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.
GO:0046761	viral budding from plasma membrane	biological_process	A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles.
GO:0046762	viral budding from endoplasmic reticulum membrane	biological_process	A viral budding that starts with formation of a membrane curvature in the host ER membrane.
GO:0046765	viral budding from nuclear membrane	biological_process	A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.
GO:0046771	viral budding from inner nuclear membrane	biological_process	The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.
GO:0046772	viral budding from outer nuclear membrane	biological_process	The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.
GO:0046773	suppression by virus of host translation termination	biological_process	Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA.
GO:0046774	suppression by virus of host intracellular interferon activity	biological_process	Any viral process that results in the inhibition of interferon activity within the host cell.
GO:0046775	suppression by virus of host cytokine production	biological_process	Any viral process that results in the inhibition of host cell cytokine production.
GO:0046776	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I	biological_process	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.
GO:0046777	protein autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
GO:0046778	modification by virus of host mRNA processing	biological_process	Any viral process that interferes with the processing of mRNA in the host cell.
GO:0046780	suppression by virus of host mRNA splicing	biological_process	Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production.
GO:0046782	regulation of viral transcription	biological_process	Any process that modulates the frequency, rate or extent of the transcription of the viral genome.
GO:0046783	modification by virus of host polysomes	biological_process	Any viral process that interferes with and inhibits the assembly and function of polysomes.
GO:0046784	viral mRNA export from host cell nucleus	biological_process	The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.
GO:0046785	microtubule polymerization	biological_process	The addition of tubulin heterodimers to one or both ends of a microtubule.
GO:0046786	viral replication complex formation and maintenance	biological_process	The process of organizing and assembling viral replication proteins in preparation for viral replication.
GO:0046787	viral DNA repair	biological_process	The process of restoring viral DNA after damage or errors in replication.
GO:0046789	host cell surface receptor binding	molecular_function	Binding to a receptor on the host cell surface.
GO:0046790	virion binding	molecular_function	Binding to a virion, either by binding to components of the capsid or the viral envelope.
GO:0046792	suppression by virus of host cell cycle arrest	biological_process	Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur.
GO:0046794	transport of virus	biological_process	The directed movement of a virus, or part of a virus, into, out of, or within a host cell.
GO:0046797	viral procapsid maturation	biological_process	The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.
GO:0046798	viral portal complex	cellular_component	A multimeric ring of proteins through which the DNA enters and exits the viral capsid.
GO:0046799	recruitment of helicase-primase complex to DNA lesions	biological_process	The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.
GO:0046802	exit of virus from host cell nucleus by nuclear egress	biological_process	The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.
GO:0046804	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide	biological_process	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine.
GO:0046805	protein-heme linkage via 1'-L-histidine	biological_process	The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).
GO:0046806	viral scaffold	cellular_component	A complex of proteins that form a scaffold around which the viral capsid is constructed.
GO:0046807	viral scaffold assembly and maintenance	biological_process	The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.
GO:0046809	replication compartment	cellular_component	Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.
GO:0046810	host cell extracellular matrix binding	molecular_function	Binding to the extracellular matrix of a host cell.
GO:0046811	histone deacetylase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.
GO:0046812	host cell surface binding	molecular_function	Binding to the surface of a host cell.
GO:0046813	receptor-mediated virion attachment to host cell	biological_process	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.
GO:0046814	coreceptor-mediated virion attachment to host cell	biological_process	The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.
GO:0046816	virion transport vesicle	cellular_component	A vesicle used to transport the partial or complete virion between cellular compartments.
GO:0046817	chemokine receptor antagonist activity	molecular_function	Interacts with chemokine receptors to reduce the action of a chemokine.
GO:0046818	dense nuclear body	cellular_component	A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.
GO:0046819	protein secretion by the type V secretion system	biological_process	The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.
GO:0046820	4-amino-4-deoxychorismate synthase activity	molecular_function	Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.
GO:0046821	extrachromosomal DNA	cellular_component	DNA structures that are not part of a chromosome.
GO:0046822	regulation of nucleocytoplasmic transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
GO:0046823	negative regulation of nucleocytoplasmic transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
GO:0046824	positive regulation of nucleocytoplasmic transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
GO:0046825	regulation of protein export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.
GO:0046826	negative regulation of protein export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.
GO:0046827	positive regulation of protein export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
GO:0046828	regulation of RNA import into nucleus	biological_process	Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.
GO:0046829	negative regulation of RNA import into nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.
GO:0046830	positive regulation of RNA import into nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.
GO:0046831	regulation of RNA export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.
GO:0046832	negative regulation of RNA export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.
GO:0046833	positive regulation of RNA export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.
GO:0046834	lipid phosphorylation	biological_process	The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
GO:0046835	carbohydrate phosphorylation	biological_process	The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.
GO:0046836	glycolipid transport	biological_process	The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0046839	phospholipid dephosphorylation	biological_process	The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
GO:0046841	trisporic acid metabolic process	biological_process	The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.
GO:0046842	trisporic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of trisporic acid.
GO:0046843	dorsal appendage formation	biological_process	Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
GO:0046844	chorion micropyle formation	biological_process	Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization.
GO:0046845	branched duct epithelial cell fate determination, open tracheal system	biological_process	Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.
GO:0046847	filopodium assembly	biological_process	The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
GO:0046848	hydroxyapatite binding	molecular_function	Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.
GO:0046849	bone remodeling	biological_process	The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
GO:0046850	regulation of bone remodeling	biological_process	Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
GO:0046851	negative regulation of bone remodeling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.
GO:0046852	positive regulation of bone remodeling	biological_process	Any process that activates or increases the frequency, rate or extent of bone remodeling.
GO:0046854	phosphatidylinositol phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.
GO:0046856	phosphatidylinositol dephosphorylation	biological_process	The process of removing one or more phosphate groups from a phosphatidylinositol.
GO:0046857	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.
GO:0046858	chlorosome	cellular_component	A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.
GO:0046859	hydrogenosomal membrane	cellular_component	The lipid bilayer surrounding a hydrogenosome.
GO:0046860	glycosome membrane	cellular_component	The lipid bilayer surrounding a glycosome.
GO:0046861	glyoxysomal membrane	cellular_component	The lipid bilayer surrounding a glyoxysome.
GO:0046862	chromoplast membrane	cellular_component	Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope.
GO:0046863	ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity	molecular_function	Binds to and iincreases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.
GO:0046864	isoprenoid transport	biological_process	The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0046865	terpenoid transport	biological_process	The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.
GO:0046866	tetraterpenoid transport	biological_process	The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.
GO:0046867	carotenoid transport	biological_process	The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
GO:0046868	mesosome	cellular_component	An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins.
GO:0046869	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide	biological_process	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.
GO:0046870	cadmium ion binding	molecular_function	Binding to a cadmium ion (Cd).
GO:0046871	N-acetylgalactosamine binding	molecular_function	Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.
GO:0046872	metal ion binding	molecular_function	Binding to a metal ion.
GO:0046873	metal ion transmembrane transporter activity	molecular_function	Enables the transfer of metal ions from one side of a membrane to the other.
GO:0046874	quinolinate metabolic process	biological_process	The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
GO:0046875	ephrin receptor binding	molecular_function	Binding to an ephrin receptor.
GO:0046876	3,4-didehydroretinal binding	molecular_function	Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).
GO:0046877	regulation of saliva secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.
GO:0046878	positive regulation of saliva secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.
GO:0046879	hormone secretion	biological_process	The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.
GO:0046880	regulation of follicle-stimulating hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
GO:0046881	positive regulation of follicle-stimulating hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
GO:0046882	negative regulation of follicle-stimulating hormone secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
GO:0046883	regulation of hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.
GO:0046884	follicle-stimulating hormone secretion	biological_process	The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
GO:0046885	regulation of hormone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
GO:0046886	positive regulation of hormone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
GO:0046887	positive regulation of hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.
GO:0046888	negative regulation of hormone secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
GO:0046889	positive regulation of lipid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GO:0046890	regulation of lipid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GO:0046891	peptidyl-cysteine S-carbamoylation	biological_process	The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine.
GO:0046892	peptidyl-S-carbamoyl-L-cysteine dehydration	biological_process	The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.
GO:0046893	iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation	biological_process	The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase.
GO:0046895	N-terminal peptidyl-isoleucine methylation	biological_process	The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine.
GO:0046896	N-terminal peptidyl-leucine methylation	biological_process	The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.
GO:0046897	N-terminal peptidyl-tyrosine methylation	biological_process	The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine.
GO:0046898	response to cycloheximide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
GO:0046899	nucleoside triphosphate adenylate kinase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
GO:0046900	tetrahydrofolylpolyglutamate metabolic process	biological_process	The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
GO:0046902	regulation of mitochondrial membrane permeability	biological_process	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
GO:0046903	secretion	biological_process	The controlled release of a substance by a cell or a tissue.
GO:0046904	calcium oxalate binding	molecular_function	Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.
GO:0046905	15-cis-phytoene synthase activity	molecular_function	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate.
GO:0046906	tetrapyrrole binding	molecular_function	Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.
GO:0046907	intracellular transport	biological_process	The directed movement of substances within a cell.
GO:0046910	pectinesterase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of pectinesterase.
GO:0046911	metal chelating activity	molecular_function	The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.
GO:0046912	acyltransferase activity, acyl groups converted into alkyl on transfer	molecular_function	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
GO:0046914	transition metal ion binding	molecular_function	Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
GO:0046915	transition metal ion transmembrane transporter activity	molecular_function	Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
GO:0046917	triphosphoribosyl-dephospho-CoA synthase activity	molecular_function	Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.
GO:0046918	N-terminal peptidyl-glycine N-palmitoylation	biological_process	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine.
GO:0046919	pyruvyltransferase activity	molecular_function	Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.
GO:0046920	alpha-(1->3)-fucosyltransferase activity	molecular_function	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.
GO:0046921	alpha-(1->6)-fucosyltransferase activity	molecular_function	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
GO:0046922	peptide-O-fucosyltransferase activity	molecular_function	Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
GO:0046923	ER retention sequence binding	molecular_function	Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.
GO:0046924	peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine	biological_process	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.
GO:0046925	peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine	biological_process	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine.
GO:0046926	peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine	biological_process	The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.
GO:0046927	peptidyl-threonine racemization	biological_process	The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.
GO:0046928	regulation of neurotransmitter secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
GO:0046929	negative regulation of neurotransmitter secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
GO:0046930	pore complex	cellular_component	A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.
GO:0046931	pore complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.
GO:0046932	sodium-transporting ATP synthase activity, rotational mechanism	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism.
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	molecular_function	Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
GO:0046934	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H+.
GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	molecular_function	Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.
GO:0046936	2'-deoxyadenosine deaminase activity	molecular_function	Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.
GO:0046937	phytochelatin metabolic process	biological_process	The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
GO:0046938	phytochelatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
GO:0046940	nucleoside monophosphate phosphorylation	biological_process	The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.
GO:0046941	azetidine-2-carboxylic acid acetyltransferase activity	molecular_function	Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.
GO:0046942	carboxylic acid transport	biological_process	The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0046943	carboxylic acid transmembrane transporter activity	molecular_function	Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0046944	protein carbamoylation	biological_process	The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.
GO:0046945	N-terminal peptidyl-alanine N-carbamoylation	biological_process	The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.
GO:0046946	hydroxylysine metabolic process	biological_process	The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases.
GO:0046947	hydroxylysine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.
GO:0046948	hydroxylysine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.
GO:0046949	fatty-acyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
GO:0046950	cellular ketone body metabolic process	biological_process	The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.
GO:0046951	ketone body biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
GO:0046952	ketone body catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
GO:0046956	positive phototaxis	biological_process	The directed movement of a cell or organism towards a source of light.
GO:0046957	negative phototaxis	biological_process	The directed movement of a cell or organism away from a source of light.
GO:0046958	nonassociative learning	biological_process	A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.
GO:0046959	habituation	biological_process	A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
GO:0046960	sensitization	biological_process	An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.
GO:0046961	proton-transporting ATPase activity, rotational mechanism	molecular_function	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out), by a rotational mechanism.
GO:0046962	sodium-transporting ATPase activity, rotational mechanism	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism.
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	biological_process	The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	molecular_function	Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.
GO:0046965	nuclear retinoid X receptor binding	molecular_function	Binding to a nuclear retinoid X receptor.
GO:0046966	nuclear thyroid hormone receptor binding	molecular_function	Binding to a nuclear thyroid hormone receptor.
GO:0046967	cytosol to endoplasmic reticulum transport	biological_process	The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.
GO:0046968	peptide antigen transport	biological_process	The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
GO:0046969	NAD-dependent histone H3K9 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
GO:0046970	NAD-dependent histone H4K16 deacetylase activity	molecular_function	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.
GO:0046972	histone H4K16 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.
GO:0046974	histone H3K9 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of up to three methyl groups to the lysine residue at position 9 of the histone H3 protein.
GO:0046975	histone H3K36 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group to the lysine residue at position 36 of the histone H3 protein.
GO:0046976	histone H3K27 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group to the lysine residue at position 27 of the histone H3 protein.
GO:0046977	TAP binding	molecular_function	Binding to TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2.
GO:0046978	TAP1 binding	molecular_function	Binding to the TAP1 subunit of TAP (transporter associated with antigen processing) protein.
GO:0046979	TAP2 binding	molecular_function	Binding to the TAP2 subunit of TAP (transporter associated with antigen processing) protein.
GO:0046980	tapasin binding	molecular_function	Binding to tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.
GO:0046981	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.
GO:0046982	protein heterodimerization activity	molecular_function	Binding to a nonidentical protein to form a heterodimer.
GO:0046983	protein dimerization activity	molecular_function	The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
GO:0046984	regulation of hemoglobin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
GO:0046985	positive regulation of hemoglobin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
GO:0046986	negative regulation of hemoglobin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
GO:0046987	N-acetyllactosamine beta-1,3-glucuronosyltransferase activity	molecular_function	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).
GO:0046988	asioloorosomucoid beta-1,3-glucuronosyltransferase activity	molecular_function	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.
GO:0046989	galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity	molecular_function	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.
GO:0046990	N-hydroxyarylamine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.
GO:0046992	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.
GO:0046993	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.
GO:0046994	oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound.
GO:0046995	oxidoreductase activity, acting on hydrogen as donor, with other known acceptors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.
GO:0046997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.
GO:0046998	(S)-usnate reductase activity	molecular_function	Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD+ = (S)-usnate + 2 H+ + NADH.
GO:0047000	2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H+ + NADPH.
GO:0047001	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.
GO:0047002	L-arabinitol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-arabinitol + NAD+ = L-ribulose + H+ + NADH.
GO:0047003	dTDP-6-deoxy-L-talose 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + H+ + NADPH.
GO:0047004	UDP-N-acetylglucosamine 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + 2 NAD+ + UDP-N-acetyl-alpha-D-glucosamine = 3 H+ + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate.
GO:0047005	16-alpha-hydroxysteroid dehydrogenase activity	molecular_function	Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.
GO:0047007	pregnan-21-ol dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: NAD+ + pregnan-21-ol = H+ + NADH + pregnan-21-al.
GO:0047008	pregnan-21-ol dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + pregnan-21-ol = H+ + NADPH + pregnan-21-al.
GO:0047009	3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.
GO:0047010	hydroxycyclohexanecarboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H+ + NADH.
GO:0047011	2-dehydropantolactone reductase (A-specific) activity	molecular_function	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
GO:0047012	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity	molecular_function	Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.
GO:0047013	cholate 12-alpha dehydrogenase activity	molecular_function	Catalysis of the reaction: cholate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.
GO:0047014	glycerol-3-phosphate 1-dehydrogenase [NADP+] activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + H+ + NADPH.
GO:0047015	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
GO:0047016	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
GO:0047017	prostaglandin-F synthase activity	molecular_function	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
GO:0047018	indole-3-acetaldehyde reductase (NADH) activity	molecular_function	Catalysis of the reaction: indole-3-ethanol + NAD+ = (indol-3-yl)acetaldehyde + H+ + NADH.
GO:0047019	indole-3-acetaldehyde reductase (NADPH) activity	molecular_function	Catalysis of the reaction: indole-3-ethanol + NADP+ = (indol-3-yl)acetaldehyde + H+ + NADPH.
GO:0047020	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H+ + NADPH.
GO:0047022	7-beta-hydroxysteroid dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.
GO:0047023	androsterone dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP+ = 17beta-hydroxy-5alpha-androstan-3-one + H+ + NADPH.
GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity	molecular_function	Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].
GO:0047026	androsterone dehydrogenase (A-specific) activity	molecular_function	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
GO:0047027	benzyl-2-methyl-hydroxybutyrate dehydrogenase activity	molecular_function	Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ = benzyl 2-methyl-3-oxobutanoate + H+ + NADPH.
GO:0047028	6-pyruvoyltetrahydropterin 2'-reductase activity	molecular_function	Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.
GO:0047029	(R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity	molecular_function	Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.
GO:0047030	4-hydroxycyclohexanecarboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + H+ + NADH.
GO:0047031	diethyl 2-methyl-3-oxosuccinate reductase activity	molecular_function	Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + H+ + NADPH.
GO:0047032	3-alpha-hydroxyglycyrrhetinate dehydrogenase activity	molecular_function	Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + H+ + NADPH.
GO:0047033	15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H+ + NADPH.
GO:0047034	15-hydroxyicosatetraenoate dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
GO:0047035	testosterone dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
GO:0047036	codeinone reductase (NADPH) activity	molecular_function	Catalysis of the reaction: codeine + NADP+ = codeinone + H+ + NADPH.
GO:0047037	salutaridine reductase (NADPH) activity	molecular_function	Catalysis of the reaction: (7S)-salutaridinol + NADP+ = H+ + NADPH + salutaridine.
GO:0047038	D-arabinitol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-arabinitol + NAD+ = D-ribulose + H+ + NADH.
GO:0047039	tetrahydroxynaphthalene reductase activity	molecular_function	Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.
GO:0047040	pteridine reductase activity	molecular_function	Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP+ = biopterin + 2 H+ + 2 NADPH.
GO:0047041	(S)-carnitine 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.
GO:0047042	androsterone dehydrogenase (B-specific) activity	molecular_function	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
GO:0047043	3-alpha-hydroxycholanate dehydrogenase activity	molecular_function	Catalysis of the reaction: lithocholate + NAD+ = 3-oxo-5beta-cholanate + H+ + NADH.
GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.
GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
GO:0047046	homoisocitrate dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.
GO:0047047	oxaloglycolate reductase (decarboxylating) activity	molecular_function	Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.
GO:0047048	3-hydroxybenzyl-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP+ = 3-hydroxybenzaldehyde + H+ + NADPH.
GO:0047049	(R)-2-hydroxy-fatty acid dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.
GO:0047050	(S)-2-hydroxy-fatty acid dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxystearate + NAD+ = 2-oxostearate + H+ + NADH.
GO:0047051	D-lactate dehydrogenase (cytochrome c-553) activity	molecular_function	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.
GO:0047052	(S)-stylopine synthase activity	molecular_function	Catalysis of the reaction: (S)-cheilanthifoline + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-stylopine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0047053	(S)-cheilanthifoline synthase activity	molecular_function	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0047054	berbamunine synthase activity	molecular_function	Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 = berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0047055	salutaridine synthase activity	molecular_function	Catalysis of the reaction: (R)-reticuline + [reduced NADPH--hemoprotein reductase] + O2 -> salutaridine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0047056	(S)-canadine synthase activity	molecular_function	Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0047057	vitamin-K-epoxide reductase (warfarin-sensitive) activity	molecular_function	Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues.
GO:0047058	vitamin-K-epoxide reductase (warfarin-insensitive) activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.
GO:0047059	polyvinyl alcohol dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.
GO:0047060	(R)-pantolactone dehydrogenase (flavin) activity	molecular_function	Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).
GO:0047061	glucose-fructose oxidoreductase activity	molecular_function	Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.
GO:0047062	trans-acenaphthene-1,2-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP+ = acenaphthene-1,2-dione + 2 H+ + 2 NADPH.
GO:0047064	sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity	molecular_function	Catalysis of the reaction: O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O.
GO:0047065	sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity	molecular_function	Catalysis of the reaction: O2 + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H2O.
GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity	molecular_function	Catalysis of the reaction: a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O.
GO:0047067	hydrogen:quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone.
GO:0047068	N5,N10-methenyltetrahydromethanopterin hydrogenase activity	molecular_function	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H+.
GO:0047069	7,8-dihydroxykynurenate 8,8a-dioxygenase activity	molecular_function	Catalysis of the reaction: 7,8-dihydroxykynurenate + O2 = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+.
GO:0047070	3-carboxyethylcatechol 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.
GO:0047071	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H+.
GO:0047072	2,3-dihydroxybenzoate 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H+.
GO:0047073	2,4'-dihydroxyacetophenone dioxygenase activity	molecular_function	Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H+.
GO:0047074	4-hydroxycatechol 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate.
GO:0047075	2,5-dihydroxypyridine 5,6-dioxygenase activity	molecular_function	Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.
GO:0047077	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	molecular_function	Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.
GO:0047078	3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity	molecular_function	Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.
GO:0047079	deoxyuridine 1'-dioxygenase activity	molecular_function	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil.
GO:0047080	deoxyuridine 2'-dioxygenase activity	molecular_function	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = CO2 + succinate + uridine.
GO:0047081	3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate.
GO:0047082	3,9-dihydroxypterocarpan 6a-monooxygenase activity	molecular_function	Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H+ + NADPH + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.
GO:0047083	5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.
GO:0047084	methyltetrahydroprotoberberine 14-monooxygenase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.
GO:0047085	hydroxyphenylacetonitrile 2-monooxygenase activity	molecular_function	Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H+ + NADPH + O2 = 4-hydroxymandelonitrile + H2O + NADP+.
GO:0047086	ketosteroid monooxygenase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.
GO:0047087	protopine 6-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + protopine = 6-hydroxyprotopine + H2O + NADP+.
GO:0047088	dihydrosanguinarine 10-monooxygenase activity	molecular_function	Catalysis of the reaction: dihydrosanguinarine + H+ + NADPH + O2 = 10-hydroxydihydrosanguinarine + H2O + NADP+.
GO:0047089	dihydrochelirubine 12-monooxygenase activity	molecular_function	Catalysis of the reaction: dihydrochelirubine + H+ + NADPH + O2 = 12-hydroxydihydrochelirubine + H2O + NADP+.
GO:0047090	benzoyl-CoA 3-monooxygenase activity	molecular_function	Catalysis of the reaction: benzoyl-CoA + H+ + NADPH + O2 = 3-hydroxybenzoyl-CoA + H2O + NADP+.
GO:0047091	L-lysine 6-monooxygenase (NADPH) activity	molecular_function	Catalysis of the reaction: L-lysine + NADPH + O2 = N(6)-hydroxy-L-lysine + H2O + NADP+.
GO:0047092	27-hydroxycholesterol 7-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.
GO:0047093	4-hydroxyquinoline 3-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADH + O2 + quinolin-4-ol = H2O + NAD+ + quinoline-3,4-diol.
GO:0047094	3-hydroxyphenylacetate 6-hydroxylase activity	molecular_function	Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.
GO:0047095	2-hydroxycyclohexanone 2-monooxygenase activity	molecular_function	Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + H2O + NADP+.
GO:0047096	androst-4-ene-3,17-dione monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O2 = A + H2O + testololactone.
GO:0047097	phylloquinone monooxygenase (2,3-epoxidizing) activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + phylloquinone = 2,3-epoxyphylloquinone + A + H2O.
GO:0047098	Latia-luciferin monooxygenase (demethylating) activity	molecular_function	Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.
GO:0047099	CDP-4-dehydro-6-deoxyglucose reductase activity	molecular_function	Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.
GO:0047100	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity	molecular_function	Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.
GO:0047101	2-oxoisovalerate dehydrogenase (acylating) activity	molecular_function	Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.
GO:0047102	aminomuconate-semialdehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.
GO:0047103	3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate.
GO:0047104	hexadecanal dehydrogenase (acylating) activity	molecular_function	Catalysis of the reaction: CoA + NAD+ + palmitaldehyde = H+ + NADH + palmitoyl-CoA.
GO:0047105	4-trimethylammoniobutyraldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.
GO:0047106	4-hydroxyphenylacetaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.
GO:0047107	gamma-guanidinobutyraldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-guanidinobutanal + H2O + NAD+ = 4-guanidinobutanoate + 2 H+ + NADH.
GO:0047108	(R)-3-hydroxyacid-ester dehydrogenase activity	molecular_function	Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.
GO:0047109	(S)-3-hydroxyacid-ester dehydrogenase activity	molecular_function	Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.
GO:0047110	phenylglyoxylate dehydrogenase (acylating) activity	molecular_function	Catalysis of the reaction: CoA + NAD+ + phenylglyoxylate = benzoyl-CoA + CO2 + NADH.
GO:0047111	formate dehydrogenase (cytochrome-c-553) activity	molecular_function	Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.
GO:0047112	pyruvate oxidase activity	molecular_function	Catalysis of the reaction: H+ + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2.
GO:0047113	aldehyde dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol.
GO:0047114	kynurenate-7,8-dihydrodiol dehydrogenase activity	molecular_function	Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.
GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
GO:0047116	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.
GO:0047117	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	molecular_function	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+.
GO:0047118	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity	molecular_function	Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H+ + NADPH.
GO:0047120	(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ = 3,4-dihydroxybenzoate + CO2 + NADH.
GO:0047121	isoquinoline 1-oxidoreductase activity	molecular_function	Catalysis of the reaction: A + H2O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.
GO:0047122	quinaldate 4-oxidoreductase activity	molecular_function	Catalysis of the reaction: A + H2O + quinaldate = AH(2) + kynurenate.
GO:0047123	quinoline-4-carboxylate 2-oxidoreductase activity	molecular_function	Catalysis of the reaction: A + H2O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2).
GO:0047124	L-erythro-3,5-diaminohexanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H2O + NAD+ = (S)-5-amino-3-oxo-hexanoate + H+ + NADH + NH4.
GO:0047125	delta1-piperideine-2-carboxylate reductase activity	molecular_function	Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate.
GO:0047126	N5-(carboxyethyl)ornithine synthase activity	molecular_function	Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H2O + NADP+ = L-ornithine + H+ + NADPH + pyruvate.
GO:0047127	thiomorpholine-carboxylate dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.
GO:0047128	1,2-dehydroreticulinium reductase (NADPH) activity	molecular_function	Catalysis of the reaction: (R)-reticuline + NADP+ = 1,2-dehydroreticuline + H+ + NADPH.
GO:0047129	opine dehydrogenase activity	molecular_function	Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H2O + NAD+ = L-2-aminopentanoate + H+ + NADH + pyruvate.
GO:0047130	saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	molecular_function	Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH.
GO:0047131	saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity	molecular_function	Catalysis of the reaction: L-saccharopine + H2O + NAD+ = L-glutamate + allysine + H+ + NADH.
GO:0047132	dihydrobenzophenanthridine oxidase activity	molecular_function	Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine.
GO:0047133	dimethylamine dehydrogenase activity	molecular_function	Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.
GO:0047134	protein-disulfide reductase (NAD(P)) activity	molecular_function	Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
GO:0047135	bis-gamma-glutamylcystine reductase activity	molecular_function	Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP+ = bis-gamma-glutamylcystine + H+ + NADPH.
GO:0047136	4-(dimethylamino)phenylazoxybenzene reductase activity	molecular_function	Catalysis of the reaction: 4-(dimethylamino)azobenzene + H2O + NADP+ = 4-(dimethylamino)phenylazoxybenzene + H+ + NADPH.
GO:0047137	N-hydroxy-2-acetamidofluorene reductase activity	molecular_function	Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.
GO:0047139	glutathione-homocystine transhydrogenase activity	molecular_function	Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.
GO:0047140	glutathione-CoA-glutathione transhydrogenase activity	molecular_function	Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.
GO:0047141	glutathione-cystine transhydrogenase activity	molecular_function	Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.
GO:0047142	enzyme-thiol transhydrogenase (glutathione-disulfide) activity	molecular_function	Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase.
GO:0047143	chlorate reductase activity	molecular_function	Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H2O + H+.
GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity	molecular_function	Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.
GO:0047145	demethylsterigmatocystin 6-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.
GO:0047146	sterigmatocystin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.
GO:0047147	trimethylsulfonium-tetrahydrofolate N-methyltransferase activity	molecular_function	Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H+.
GO:0047148	methylamine-glutamate N-methyltransferase activity	molecular_function	Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH4.
GO:0047149	thetin-homocysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H+.
GO:0047150	betaine-homocysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.
GO:0047151	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.
GO:0047152	methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity	molecular_function	Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.
GO:0047153	deoxycytidylate 5-hydroxymethyltransferase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.
GO:0047154	methylmalonyl-CoA carboxytransferase activity	molecular_function	Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.
GO:0047155	3-hydroxymethylcephem carbamoyltransferase activity	molecular_function	Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.
GO:0047156	acetoin-ribose-5-phosphate transaldolase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde.
GO:0047157	myelin-proteolipid O-palmitoyltransferase activity	molecular_function	Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.
GO:0047158	sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity	molecular_function	Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.
GO:0047159	1-alkenylglycerophosphocholine O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.
GO:0047160	alkylglycerophosphate 2-O-acetyltransferase activity	molecular_function	Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.
GO:0047161	tartronate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.
GO:0047162	17-O-deacetylvindoline O-acetyltransferase activity	molecular_function	Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.
GO:0047163	3,4-dichloroaniline N-malonyltransferase activity	molecular_function	Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA.
GO:0047164	isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.
GO:0047165	flavonol-3-O-beta-glucoside O-malonyltransferase activity	molecular_function	Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.
GO:0047166	1-alkenylglycerophosphoethanolamine O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.
GO:0047167	1-alkyl-2-acetylglycerol O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.
GO:0047168	isocitrate O-dihydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA.
GO:0047169	galactarate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.
GO:0047170	glucarate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.
GO:0047171	glucarolactone O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.
GO:0047172	shikimate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.
GO:0047173	phosphatidylcholine-retinol O-acyltransferase activity	molecular_function	Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.
GO:0047174	putrescine N-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H+.
GO:0047175	galactosylacylglycerol O-acyltransferase activity	molecular_function	Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].
GO:0047176	beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity	molecular_function	Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose.
GO:0047177	glycerophospholipid arachidonoyl-transferase (CoA-independent) activity	molecular_function	Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine.
GO:0047178	glycerophospholipid acyltransferase (CoA-dependent) activity	molecular_function	Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.
GO:0047179	platelet-activating factor acetyltransferase activity	molecular_function	Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.
GO:0047180	salutaridinol 7-O-acetyltransferase activity	molecular_function	Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.
GO:0047181	tetrahydroxybenzophenone synthase activity	molecular_function	Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.
GO:0047182	alcohol O-cinnamoyltransferase activity	molecular_function	Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.
GO:0047183	anthocyanin 5-aromatic acyltransferase activity	molecular_function	Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.
GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
GO:0047185	N-acetylneuraminate 4-O-acetyltransferase activity	molecular_function	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.
GO:0047186	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	molecular_function	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.
GO:0047187	deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity	molecular_function	Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate.
GO:0047188	aromatic-hydroxylamine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl.
GO:0047189	2,3-diaminopropionate N-oxalyltransferase activity	molecular_function	Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA.
GO:0047190	2-acylglycerophosphocholine O-acyltransferase activity	molecular_function	Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.
GO:0047191	1-alkylglycerophosphocholine O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.
GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.
GO:0047194	indoleacetylglucose-inositol O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.
GO:0047195	diacylglycerol-sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol.
GO:0047196	long-chain-alcohol O-fatty-acyltransferase activity	molecular_function	Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.
GO:0047197	triglyceride-sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.
GO:0047198	cysteine-S-conjugate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.
GO:0047199	phosphatidylcholine-dolichol O-acyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol.
GO:0047200	tetrahydrodipicolinate N-acetyltransferase activity	molecular_function	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6-oxopimelate + CoA.
GO:0047201	beta-glucogallin O-galloyltransferase activity	molecular_function	Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.
GO:0047202	sinapoylglucose-choline O-sinapoyltransferase activity	molecular_function	Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.
GO:0047203	13-hydroxylupinine O-tigloyltransferase activity	molecular_function	Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.
GO:0047204	chlorogenate-glucarate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.
GO:0047205	quinate O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.
GO:0047206	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala).
GO:0047207	1,2-beta-fructan 1F-fructosyltransferase activity	molecular_function	Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).
GO:0047208	o-dihydroxycoumarin 7-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H+ + UDP.
GO:0047209	coniferyl-alcohol glucosyltransferase activity	molecular_function	Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.
GO:0047211	alpha-1,4-glucan-protein synthase (ADP-forming) activity	molecular_function	Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.
GO:0047212	2-coumarate O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H+ + UDP.
GO:0047213	anthocyanidin 3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP.
GO:0047214	cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP.
GO:0047215	indole-3-acetate beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.
GO:0047216	inositol 3-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.
GO:0047217	sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity	molecular_function	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.
GO:0047218	hydroxycinnamate 4-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP.
GO:0047219	monoterpenol beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H+ + UDP.
GO:0047220	galactosylxylosylprotein 3-beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.
GO:0047221	sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H+ + UDP.
GO:0047222	mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.
GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.
GO:0047224	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP.
GO:0047225	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.
GO:0047227	indolylacetyl-myo-inositol galactosyltransferase activity	molecular_function	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H+ + UDP.
GO:0047228	1,2-diacylglycerol 3-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP.
GO:0047229	13-hydroxydocosanoate 13-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.
GO:0047230	flavonol-3-O-glucoside L-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.
GO:0047231	pyridoxine 5'-O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H+ + UDP.
GO:0047232	galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.
GO:0047233	N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.
GO:0047234	raffinose-raffinose alpha-galactotransferase activity	molecular_function	Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.
GO:0047235	sucrose 6F-alpha-galactotransferase activity	molecular_function	Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.
GO:0047236	methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.
GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.
GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.
GO:0047239	hydroxymandelonitrile glucosyltransferase activity	molecular_function	Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H+ + taxiphyllin + UDP.
GO:0047240	lactosylceramide beta-1,3-galactosyltransferase activity	molecular_function	Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H+ + UDP.
GO:0047241	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity	molecular_function	Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.
GO:0047242	hydroxyanthraquinone glucosyltransferase activity	molecular_function	Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.
GO:0047243	flavanone 7-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.
GO:0047244	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.
GO:0047245	N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.
GO:0047246	luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.
GO:0047247	luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.
GO:0047248	nuatigenin 3-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: nuatigenin + UDP-D-glucose = H+ + nuatigenin 3-beta-D-glucopyranoside + UDP.
GO:0047249	sarsapogenin 3-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H+ + UDP.
GO:0047250	4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H+ + UDP.
GO:0047251	thiohydroximate beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.
GO:0047252	beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity	molecular_function	Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.
GO:0047253	alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.
GO:0047254	2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.
GO:0047255	galactogen 6-beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.
GO:0047256	lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	molecular_function	Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.
GO:0047257	diglucosyl diacylglycerol synthase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.
GO:0047258	sphingosine beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: sphingosine + UDP-D-galactose = H+ + psychosine + UDP.
GO:0047259	glucomannan 4-beta-mannosyltransferase activity	molecular_function	Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.
GO:0047260	alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity	molecular_function	Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.
GO:0047261	steroid N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H+ + UDP.
GO:0047262	polygalacturonate 4-alpha-galacturonosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.
GO:0047263	N-acylsphingosine galactosyltransferase activity	molecular_function	Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP.
GO:0047264	heteroglycan alpha-mannosyltransferase activity	molecular_function	Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.
GO:0047265	poly(glycerol-phosphate) alpha-glucosyltransferase activity	molecular_function	Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.
GO:0047266	poly(ribitol-phosphate) beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.
GO:0047267	undecaprenyl-phosphate mannosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.
GO:0047268	galactinol-raffinose galactosyltransferase activity	molecular_function	Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.
GO:0047269	poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.
GO:0047270	lipopolysaccharide glucosyltransferase II activity	molecular_function	Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.
GO:0047271	glycosaminoglycan galactosyltransferase activity	molecular_function	Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.
GO:0047272	phosphopolyprenol glucosyltransferase activity	molecular_function	Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.
GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.
GO:0047274	galactinol-sucrose galactosyltransferase activity	molecular_function	Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.
GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.
GO:0047277	globoside alpha-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
GO:0047278	bilirubin-glucuronoside glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.
GO:0047279	sn-glycerol-3-phosphate 1-galactosyltransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H+ + UDP.
GO:0047280	nicotinamide phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H+ + nicotinamide.
GO:0047281	dioxotetrahydropyrimidine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.
GO:0047282	dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity	molecular_function	Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H+.
GO:0047283	dolichyl-phosphate D-xylosyltransferase activity	molecular_function	Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.
GO:0047284	dolichyl-xylosyl-phosphate-protein xylosyltransferase activity	molecular_function	Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.
GO:0047285	flavonol-3-O-glycoside xylosyltransferase activity	molecular_function	Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.
GO:0047286	NAD+-diphthamide ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.
GO:0047288	beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase	molecular_function	Catalysis of the reaction: beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+).
GO:0047289	galactosyldiacylglycerol alpha-2,3-sialyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H+.
GO:0047290	alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	molecular_function	Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.
GO:0047291	lactosylceramide alpha-2,3-sialyltransferase activity	molecular_function	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.
GO:0047292	trihydroxypterocarpan dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.
GO:0047293	4-hydroxybenzoate nonaprenyltransferase activity	molecular_function	Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.
GO:0047294	phosphoglycerol geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.
GO:0047295	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity	molecular_function	Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.
GO:0047296	homospermidine synthase activity	molecular_function	Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.
GO:0047297	asparagine-oxo-acid transaminase activity	molecular_function	Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate.
GO:0047298	(S)-3-amino-2-methylpropionate transaminase activity	molecular_function	Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.
GO:0047299	tryptophan-phenylpyruvate transaminase activity	molecular_function	Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine.
GO:0047300	pyridoxamine-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.
GO:0047301	valine-3-methyl-2-oxovalerate transaminase activity	molecular_function	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.
GO:0047302	UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.
GO:0047303	glycine-oxaloacetate transaminase activity	molecular_function	Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.
GO:0047304	2-aminoethylphosphonate-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.
GO:0047305	(R)-3-amino-2-methylpropionate-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.
GO:0047306	D-methionine-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.
GO:0047307	diaminobutyrate-pyruvate transaminase activity	molecular_function	Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.
GO:0047308	alanine-oxomalonate transaminase activity	molecular_function	Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.
GO:0047309	dihydroxyphenylalanine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate.
GO:0047310	glutamine-scyllo-inositol transaminase activity	molecular_function	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.
GO:0047311	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity	molecular_function	Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.
GO:0047312	L-phenylalanine:pyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.
GO:0047313	aromatic-amino-acid-glyoxylate transaminase activity	molecular_function	Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.
GO:0047315	kynurenine-glyoxylate transaminase activity	molecular_function	Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
GO:0047316	glutamine-phenylpyruvate transaminase activity	molecular_function	Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.
GO:0047317	N6-acetyl-beta-lysine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.
GO:0047319	aspartate-phenylpyruvate transaminase activity	molecular_function	Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.
GO:0047320	D-4-hydroxyphenylglycine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.
GO:0047321	diphosphate-protein phosphotransferase activity	molecular_function	Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.
GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	molecular_function	Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.
GO:0047323	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	molecular_function	Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.
GO:0047324	phosphoenolpyruvate-glycerone phosphotransferase activity	molecular_function	Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
GO:0047325	inositol tetrakisphosphate 1-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
GO:0047326	inositol tetrakisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
GO:0047327	glycerol-3-phosphate-glucose phosphotransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.
GO:0047328	acyl-phosphate-hexose phosphotransferase activity	molecular_function	Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.
GO:0047329	phosphoramidate-hexose phosphotransferase activity	molecular_function	Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.
GO:0047330	polyphosphate-glucose phosphotransferase activity	molecular_function	Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.
GO:0047331	diphosphate-glycerol phosphotransferase activity	molecular_function	Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H+ + phosphate.
GO:0047332	diphosphate-serine phosphotransferase activity	molecular_function	Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H+ + phosphate.
GO:0047333	dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity	molecular_function	Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H+.
GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	molecular_function	Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.
GO:0047335	3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity	molecular_function	Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.
GO:0047336	5-methyldeoxycytidine-5'-phosphate kinase activity	molecular_function	Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H+.
GO:0047337	dolichyl-diphosphate-polyphosphate phosphotransferase activity	molecular_function	Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.
GO:0047338	UTP:xylose-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.
GO:0047339	nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.
GO:0047341	fucose-1-phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP + H+ = diphosphate + GDP-beta-L-fucose.
GO:0047342	galactose-1-phosphate thymidylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.
GO:0047343	glucose-1-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.
GO:0047344	glucose-1-phosphate guanylyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.
GO:0047345	ribose-5-phosphate adenylyltransferase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + ADP + H+ = ADP-ribose + phosphate.
GO:0047346	aldose-1-phosphate adenylyltransferase activity	molecular_function	Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.
GO:0047347	aldose-1-phosphate nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.
GO:0047348	glycerol-3-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.
GO:0047349	D-ribitol-5-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.
GO:0047350	glucuronate-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.
GO:0047351	GTP guanylyltransferase activity	molecular_function	Catalysis of the reaction: 2 GTP + H+ = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H+.
GO:0047352	adenylylsulfate-ammonia adenylyltransferase activity	molecular_function	Catalysis of the reaction: 5'-adenylyl sulfate + NH4 = adenosine 5'-phosphoramidate + 2 H+ + sulfate.
GO:0047353	N-methylphosphoethanolamine cytidylyltransferase activity	molecular_function	Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.
GO:0047354	sphingosine cholinephosphotransferase activity	molecular_function	Catalysis of the reaction: CDP-choline + sphingosine = CMP + H+ + sphingosyl-phosphocholine.
GO:0047355	CDP-glycerol glycerophosphotransferase activity	molecular_function	Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.
GO:0047356	CDP-ribitol ribitolphosphotransferase activity	molecular_function	Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.
GO:0047357	UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H+ + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.
GO:0047358	UDP-glucose-glycoprotein glucose phosphotransferase activity	molecular_function	Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.
GO:0047359	1-alkenyl-2-acylglycerol choline phosphotransferase activity	molecular_function	Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.
GO:0047360	undecaprenyl-phosphate galactose phosphotransferase activity	molecular_function	Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.
GO:0047361	phosphomannan mannosephosphotransferase activity	molecular_function	Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.
GO:0047362	thiosulfate-dithiol sulfurtransferase activity	molecular_function	Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.
GO:0047363	triglucosylalkylacylglycerol sulfotransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.
GO:0047364	desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H+.
GO:0047365	quercetin-3-sulfate 3'-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,3'-disulfate.
GO:0047366	quercetin-3-sulfate 4'-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H+ + quercetin 3,4'-disulfate.
GO:0047367	quercetin-3,3'-bissulfate 7-sulfotransferase activity	molecular_function	Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.
GO:0047368	UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H+ + UDP-N-acetyl-D-galactosamine 4,6-disulfate.
GO:0047369	succinate-hydroxymethylglutarate CoA-transferase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.
GO:0047370	succinate-citramalate CoA-transferase activity	molecular_function	Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.
GO:0047371	butyrate-acetoacetate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.
GO:0047372	acylglycerol lipase activity	molecular_function	Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
GO:0047373	acetoxybutynylbithiophene deacetylase activity	molecular_function	Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H+.
GO:0047374	methylumbelliferyl-acetate deacetylase activity	molecular_function	Catalysis of the reaction: 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H+.
GO:0047375	N-acetylgalactosaminoglycan deacetylase activity	molecular_function	Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.
GO:0047376	all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity	molecular_function	Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.
GO:0047377	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity	molecular_function	Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H+.
GO:0047378	acetylalkylglycerol acetylhydrolase activity	molecular_function	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H2O = 1-alkyl-sn-glycerol + acetate + H+.
GO:0047379	ADP-dependent short-chain-acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.
GO:0047380	ADP-dependent medium-chain-acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP.
GO:0047381	dodecanoyl-[acyl-carrier-protein] hydrolase activity	molecular_function	Catalysis of the reaction: dodecanoyl-[ACP] + H2O = dodecanoate + H+ + holo-[ACP].
GO:0047382	methylphosphothioglycerate phosphatase activity	molecular_function	Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H2O = S-methyl-1-thio-D-glycerate + phosphate.
GO:0047383	guanidinodeoxy-scyllo-inositol-4-phosphatase activity	molecular_function	Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.
GO:0047384	[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity	molecular_function	Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].
GO:0047385	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity	molecular_function	Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)].
GO:0047386	fructose-2,6-bisphosphate 6-phosphatase activity	molecular_function	Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructofuranose 2-phosphate + phosphate.
GO:0047387	serine-ethanolaminephosphate phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + serine phosphoethanolamine = H+ + phosphoethanolamine + serine.
GO:0047388	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	molecular_function	Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].
GO:0047389	glycerophosphocholine phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.
GO:0047390	glycerophosphocholine cholinephosphodiesterase activity	molecular_function	Catalysis of the reaction: sn-glycero-3-phosphocholine + H2O = choline phosphate + glycerol + H+.
GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.
GO:0047392	CMP-N-acylneuraminate phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.
GO:0047393	glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity	molecular_function	Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H2O = glycerol 1-phosphate + H+.
GO:0047394	glycerophosphoinositol inositolphosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.
GO:0047395	glycerophosphoinositol glycerophosphodiesterase activity	molecular_function	Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.
GO:0047396	glycosylphosphatidylinositol diacylglycerol-lyase activity	molecular_function	Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.
GO:0047397	dolichylphosphate-glucose phosphodiesterase activity	molecular_function	Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.
GO:0047398	dolichylphosphate-mannose phosphodiesterase activity	molecular_function	Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.
GO:0047399	glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.
GO:0047400	phosphonoacetate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + phosphonoacetate = acetate + H+ + phosphate.
GO:0047401	trithionate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + trithionate = H+ + sulfate + thiosulfate.
GO:0047402	protein-glucosylgalactosylhydroxylysine glucosidase activity	molecular_function	Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.
GO:0047403	lacto-N-biosidase activity	molecular_function	Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.
GO:0047404	glucuronosyl-disulfoglucosamine glucuronidase activity	molecular_function	Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.
GO:0047405	pyrimidine-5'-nucleotide nucleosidase activity	molecular_function	Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.
GO:0047406	beta-aspartyl-N-acetylglucosaminidase activity	molecular_function	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-D-glucosamine + L-asparagine.
GO:0047407	ADP-ribosyl-[dinitrogen reductase] hydrolase activity	molecular_function	Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase].
GO:0047408	alkenylglycerophosphocholine hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.
GO:0047409	alkenylglycerophosphoethanolamine hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde.
GO:0047410	N-formylmethionylaminoacyl-tRNA deformylase activity	molecular_function	Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate.
GO:0047411	2-(acetamidomethylene)succinate hydrolase activity	molecular_function	Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate.
GO:0047412	N-(long-chain-acyl)ethanolamine deacylase activity	molecular_function	Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.
GO:0047413	N(alpha)-benzyloxycarbonylleucine hydrolase activity	molecular_function	Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H2O + H+ = L-leucine + benzyl alcohol + CO2.
GO:0047414	2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity	molecular_function	Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H2O + H+ = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4.
GO:0047415	D-benzoylarginine-4-nitroanilide amidase activity	molecular_function	Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H2O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H+.
GO:0047416	arylalkyl acylamidase activity	molecular_function	Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.
GO:0047417	N-carbamoyl-D-amino acid hydrolase activity	molecular_function	Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.
GO:0047418	phthalyl amidase activity	molecular_function	Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.
GO:0047419	N-acetylgalactosamine-6-phosphate deacetylase activity	molecular_function	Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.
GO:0047420	N-acyl-D-amino-acid deacylase activity	molecular_function	Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.
GO:0047421	N-acyl-D-glutamate deacylase activity	molecular_function	Catalysis of the reaction: N-acyl-D-glutamate + H2O = D-glutamate + a carboxylate.
GO:0047422	N-acyl-D-aspartate deacylase activity	molecular_function	Catalysis of the reaction: N-acyl-D-aspartate + H2O = D-aspartate + a carboxylate.
GO:0047423	N-methylhydantoinase (ATP-hydrolyzing) activity	molecular_function	Catalysis of the reaction: N-methylhydantoin + ATP + 2 H2O = N-carbamoylsarcosine + ADP + 3 H+ + phosphate.
GO:0047424	methylenediurea deaminase activity	molecular_function	Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.
GO:0047425	1-pyrroline-4-hydroxy-2-carboxylate deaminase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H2O + H+ = 2,5-dioxopentanoate + NH4.
GO:0047426	ricinine nitrilase activity	molecular_function	Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone.
GO:0047427	cyanoalanine nitrilase activity	molecular_function	Catalysis of the reaction: 3-cyano-L-alanine + 2 H2O + H+ = L-aspartate + NH4.
GO:0047428	arylacetonitrilase activity	molecular_function	Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3.
GO:0047429	nucleoside triphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.
GO:0047430	oligosaccharide-diphosphodolichol diphosphatase activity	molecular_function	Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.
GO:0047431	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity	molecular_function	Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H+ = 5-hydroxy-6-methylpyridine-3-carboxylate + CO2.
GO:0047432	2,2-dialkylglycine decarboxylase (pyruvate) activity	molecular_function	Catalysis of the reaction: 2,2-dialkylglycine + H+ + pyruvate = L-alanine + CO2 + dialkyl ketone.
GO:0047433	branched-chain-2-oxoacid decarboxylase activity	molecular_function	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H+ = 2-methylbutanal + CO2.
GO:0047434	indolepyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.
GO:0047435	5-guanidino-2-oxopentanoate decarboxylase activity	molecular_function	Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H+ = 4-guanidinobutanal + CO2.
GO:0047436	arylmalonate decarboxylase activity	molecular_function	Catalysis of the reaction: 2-aryl-2-methylmalonate + H+ = 2-arylpropionate + CO2.
GO:0047437	4-oxalocrotonate decarboxylase activity	molecular_function	Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.
GO:0047438	2-dehydro-3-deoxy-L-pentonate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.
GO:0047439	3-deoxy-D-manno-octulosonate aldolase activity	molecular_function	Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.
GO:0047440	2-dehydro-3-deoxy-D-pentonate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.
GO:0047441	5-dehydro-2-deoxyphosphogluconate aldolase activity	molecular_function	Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.
GO:0047442	17-alpha-hydroxyprogesterone aldolase activity	molecular_function	Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.
GO:0047443	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.
GO:0047444	N-acylneuraminate-9-phosphate synthase activity	molecular_function	Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.
GO:0047445	3-hydroxy-3-isohexenylglutaryl-CoA lyase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H+ = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.
GO:0047446	(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity	molecular_function	Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.
GO:0047447	erythro-3-hydroxyaspartate ammonia-lyase activity	molecular_function	Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.
GO:0047448	5-dehydro-4-deoxyglucarate dehydratase activity	molecular_function	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.
GO:0047449	2-dehydro-3-deoxy-L-arabinonate dehydratase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O.
GO:0047450	(3R)-hydroxybutanoyl-[acyl-carrier-protein] hydratase activity	molecular_function	Catalysis of the reaction: (3R)-hydroxybutanoyl-[acyl-carrier-protein] = (2E)-butenoyl-[acyl-carrier-protein] + H2O.
GO:0047451	(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O +  (2E)-octenoyl-[acyl-carrier protein].
GO:0047452	protoaphin-aglucone dehydratase (cyclizing) activity	molecular_function	Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin.
GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity	molecular_function	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H+ + NADH + phosphate.
GO:0047454	phaseollidin hydratase activity	molecular_function	Catalysis of the reaction: phaseollidin hydrate = H2O + phaseollidin.
GO:0047455	16-alpha-hydroxyprogesterone dehydratase activity	molecular_function	Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.
GO:0047456	2-methylisocitrate dehydratase activity	molecular_function	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H2O.
GO:0047457	exo-(1,4)-alpha-D-glucan lyase activity	molecular_function	Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.
GO:0047458	beta-pyrazolylalanine synthase activity	molecular_function	Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H+.
GO:0047459	3-aminobutyryl-CoA ammonia-lyase activity	molecular_function	Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH4.
GO:0047460	L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity	molecular_function	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H2O = 2-oxopent-4-enoate + chloride + H+ + NH4.
GO:0047461	(+)-delta-cadinene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.
GO:0047462	phenylalanine racemase (ATP-hydrolyzing) activity	molecular_function	Catalysis of the reaction: L-phenylalanine + ATP + H2O = D-phenylalanine + AMP + diphosphate + 2 H+.
GO:0047463	2-aminohexano-6-lactam racemase activity	molecular_function	Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.
GO:0047464	heparosan-N-sulfate-glucuronate 5-epimerase activity	molecular_function	Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.
GO:0047465	N-acylglucosamine-6-phosphate 2-epimerase activity	molecular_function	Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.
GO:0047466	2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity	molecular_function	Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.
GO:0047467	4-hydroxyphenylacetaldehyde-oxime isomerase activity	molecular_function	Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime.
GO:0047468	phosphoglucomutase (glucose-cofactor) activity	molecular_function	Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor.
GO:0047469	4-carboxymethyl-4-methylbutenolide mutase activity	molecular_function	Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.
GO:0047470	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity	molecular_function	Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.
GO:0047471	maltose alpha-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: maltose = trehalose.
GO:0047472	3-carboxy-cis,cis-muconate cycloisomerase activity	molecular_function	Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H+.
GO:0047473	D-alanine [D-alanyl carrier protein] ligase activity	molecular_function	Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.
GO:0047474	long-chain fatty acid luciferin component ligase activity	molecular_function	Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0047475	phenylacetate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H+ + phenylacetyl-CoA.
GO:0047476	3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity	molecular_function	Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.
GO:0047478	aspartate-ammonia ligase (ADP-forming) activity	molecular_function	Catalysis of the reaction: L-aspartate + ATP + NH4 = L-asparagine + ADP + 2 H+ + phosphate.
GO:0047479	trypanothione synthase activity	molecular_function	Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.
GO:0047480	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
GO:0047481	D-alanine-alanyl-poly(glycerolphosphate) ligase activity	molecular_function	Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.
GO:0047482	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity	molecular_function	Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.
GO:0047483	imidazoleacetate-phosphoribosyldiphosphate ligase activity	molecular_function	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H+ + phosphate.
GO:0047484	regulation of response to osmotic stress	biological_process	Any process that modulates the rate or extent of the response to osmotic stress.
GO:0047487	oligogalacturonide lyase activity	molecular_function	Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.
GO:0047488	heparin lyase activity	molecular_function	Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.
GO:0047489	pectate disaccharide-lyase activity	molecular_function	Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.
GO:0047490	pectin lyase activity	molecular_function	Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.
GO:0047491	poly(alpha-L-guluronate) lyase activity	molecular_function	Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.
GO:0047492	xanthan lyase activity	molecular_function	Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.
GO:0047493	ceramide cholinephosphotransferase activity	molecular_function	Catalysis of the reaction: CDP-choline + ceramide = CMP + H+ + sphingomyelin.
GO:0047494	serine-phosphoethanolamine synthase activity	molecular_function	Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H+.
GO:0047495	membrane-oligosaccharide glycerophosphotransferase activity	molecular_function	Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.
GO:0047496	vesicle transport along microtubule	biological_process	The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
GO:0047497	mitochondrion transport along microtubule	biological_process	The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
GO:0047498	calcium-dependent phospholipase A2 activity	molecular_function	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
GO:0047499	calcium-independent phospholipase A2 activity	molecular_function	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
GO:0047500	(+)-borneol dehydrogenase activity	molecular_function	Catalysis of the reaction: (+)-borneol + NAD+ = (1R, 4R)-camphor + H+ + NADH.
GO:0047501	(+)-neomenthol dehydrogenase activity	molecular_function	Catalysis of the reaction: (+)-neomenthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.
GO:0047502	(+)-sabinol dehydrogenase activity	molecular_function	Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (1S,5S)-sabinone + H+ + NADH.
GO:0047503	(-)-borneol dehydrogenase activity	molecular_function	Catalysis of the reaction: (-)-borneol + NAD+ = (1S,4S)-camphor + H+ + NADH.
GO:0047504	(-)-menthol dehydrogenase activity	molecular_function	Catalysis of the reaction: (-)-menthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.
GO:0047505	(-)-menthol monooxygenase activity	molecular_function	Catalysis of the reaction: (-)-menthol + H+ + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP+.
GO:0047506	(deoxy)adenylate kinase activity	molecular_function	Catalysis of the reaction: ATP + dAMP = ADP + dADP.
GO:0047507	(deoxy)nucleoside-phosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.
GO:0047508	(R)-2-methylmalate dehydratase activity	molecular_function	Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H2O.
GO:0047509	(R)-dehydropantoate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-4-dehydropantoate + H2O + NAD+ = (R)-3,3-dimethylmalate + 2 H+ + NADH.
GO:0047510	(S)-2-methylmalate dehydratase activity	molecular_function	Catalysis of the reaction: S-citramalate = H2O + mesaconate.
GO:0047511	(S)-methylmalonyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: (S)-methylmalonyl-CoA + H2O = CoA + H+ + methylmalonate.
GO:0047512	(S,S)-butanediol dehydrogenase activity	molecular_function	Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD+ = acetoin + H+ + NADH.
GO:0047513	1,2-alpha-L-fucosidase activity	molecular_function	Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.
GO:0047514	1,3-beta-D-glucan phosphorylase activity	molecular_function	Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
GO:0047515	1,3-beta-oligoglucan phosphorylase activity	molecular_function	Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.
GO:0047516	1,3-propanediol dehydrogenase activity	molecular_function	Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.
GO:0047517	1,4-beta-D-xylan synthase activity	molecular_function	Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).
GO:0047518	1-methyladenosine nucleosidase activity	molecular_function	Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + ribofuranose.
GO:0047519	quinate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.
GO:0047520	11-cis-retinyl-palmitate hydrolase activity	molecular_function	Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + H+ + palmitate.
GO:0047521	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	molecular_function	Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.
GO:0047522	15-oxoprostaglandin 13-oxidase activity	molecular_function	Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.
GO:0047524	16-hydroxysteroid epimerase activity	molecular_function	Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.
GO:0047525	2'-hydroxydaidzein reductase activity	molecular_function	Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.
GO:0047526	2'-hydroxyisoflavone reductase activity	molecular_function	Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.
GO:0047527	2,3-dihydroxybenzoate-serine ligase activity	molecular_function	Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.
GO:0047528	2,3-dihydroxyindole 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2 + H+.
GO:0047529	2,3-dimethylmalate lyase activity	molecular_function	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.
GO:0047530	2,4-diaminopentanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.
GO:0047532	2,5-dioxopiperazine hydrolase activity	molecular_function	Catalysis of the reaction: 2,5-dioxopiperazine + H2O = glycylglycine.
GO:0047533	2,5-dioxovalerate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.
GO:0047534	2-acetolactate mutase activity	molecular_function	Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.
GO:0047535	2-alkyn-1-ol dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.
GO:0047536	2-aminoadipate transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
GO:0047537	2-aminohexanoate transaminase activity	molecular_function	Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.
GO:0047538	2-carboxy-D-arabinitol-1-phosphatase activity	molecular_function	Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate.
GO:0047539	2-deoxyglucosidase activity	molecular_function	Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.
GO:0047540	2-enoate reductase activity	molecular_function	Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.
GO:0047541	2-furoate-CoA ligase activity	molecular_function	Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H+.
GO:0047542	2-furoyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH(2) + H+.
GO:0047543	2-hexadecenal reductase activity	molecular_function	Catalysis of the reaction: NADP+ + palmitaldehyde = trans-hexadec-2-enal + H+ + NADPH.
GO:0047544	2-hydroxybiphenyl 3-monooxygenase activity	molecular_function	Catalysis of the reaction: biphenyl-2-ol + H+ + NADH + O2 = biphenyl-2,3-diol + H2O + NAD+.
GO:0047545	2-hydroxyglutarate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
GO:0047546	2-hydroxypyridine 5-monooxygenase activity	molecular_function	Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O2 = 2,5-dihydroxypyridine + A + H2O.
GO:0047547	2-methylcitrate dehydratase activity	molecular_function	Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H2O.
GO:0047548	2-methyleneglutarate mutase activity	molecular_function	Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.
GO:0047549	2-nitrophenol 2-monooxygenase activity	molecular_function	Catalysis of the reaction: 2-nitrophenol + 2 H+ + 2 NADPH + O2 = catechol + H2O + 2 NADP+ + nitrite.
GO:0047550	2-oxoadipate reductase activity	molecular_function	Catalysis of the reaction: 2-hydroxyadipate + NAD+ = 2-oxoadipate + H+ + NADH.
GO:0047551	2-oxoaldehyde dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.
GO:0047552	2-oxoaldehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.
GO:0047553	2-oxoglutarate synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.
GO:0047554	2-pyrone-4,6-dicarboxylate lactonase activity	molecular_function	Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H2O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H+.
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	molecular_function	Catalysis of the reaction: 3',5'-cyclic GMP + H2O = GMP + H+.
GO:0047556	3,4-dihydroxyphthalate decarboxylase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxyphthalate + H+ = 3,4-dihydroxybenzoate + CO2.
GO:0047557	3-aci-nitropropanoate oxidase activity	molecular_function	Catalysis of the reaction: 3-aci-nitropropanoate + H2O + O2 = 3-oxopropanoate + H2O2 + nitrite.
GO:0047558	3-cyanoalanine hydratase activity	molecular_function	Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H2O + H+.
GO:0047559	3-dehydro-L-gulonate 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
GO:0047560	3-dehydrosphinganine reductase activity	molecular_function	Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH.
GO:0047561	3-hydroxyanthranilate oxidase activity	molecular_function	Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.
GO:0047562	3-hydroxyaspartate aldolase activity	molecular_function	Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.
GO:0047563	3-hydroxybenzoate 2-monooxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O2 = 2,3-dihydroxybenzoate + A + H2O.
GO:0047564	3-hydroxycyclohexanone dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.
GO:0047565	3-hydroxypropionate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + H+ + NADH.
GO:0047566	3-ketovalidoxylamine C-N-lyase activity	molecular_function	Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H+.
GO:0047567	3-methyleneoxindole reductase activity	molecular_function	Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + H+ + NADPH.
GO:0047568	3-oxo-5-beta-steroid 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.
GO:0047569	3-oxoadipate CoA-transferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.
GO:0047570	3-oxoadipate enol-lactonase activity	molecular_function	Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.
GO:0047571	3-oxosteroid 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.
GO:0047572	3-phosphoglycerate phosphatase activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glycerate + H2O = D-glycerate + phosphate.
GO:0047573	4-acetamidobutyrate deacetylase activity	molecular_function	Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.
GO:0047574	4-acetamidobutyryl-CoA deacetylase activity	molecular_function	Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate.
GO:0047575	4-carboxymuconolactone decarboxylase activity	molecular_function	Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H+ = 5-oxo-4,5-dihydro-2-furylacetate + CO2.
GO:0047576	4-chlorobenzoate dehalogenase activity	molecular_function	Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H+.
GO:0047577	4-hydroxybutyrate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-hydroxybutanoate + NAD+ = H+ + NADH + succinate semialdehyde.
GO:0047578	4-hydroxyglutamate transaminase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.
GO:0047579	4-hydroxymandelate oxidase activity	molecular_function	Catalysis of the reaction: (S)-4-hydroxymandelate + H+ + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2.
GO:0047580	4-hydroxyproline epimerase activity	molecular_function	Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.
GO:0047581	4-methyleneglutamate-ammonia ligase activity	molecular_function	Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH4 = 4-methylene-L-glutamine + AMP + diphosphate + 2 H+.
GO:0047582	4-methyleneglutaminase activity	molecular_function	Catalysis of the reaction: 4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH4.
GO:0047583	4-methyloxaloacetate esterase activity	molecular_function	Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H2O = H+ + methanol + oxaloacetate.
GO:0047584	4-oxalmesaconate hydratase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H2O.
GO:0047585	4-pyridoxolactonase activity	molecular_function	Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate + H+.
GO:0047586	5'-acylphosphoadenosine hydrolase activity	molecular_function	Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.
GO:0047587	5-alpha-hydroxysteroid dehydratase activity	molecular_function	Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H2O.
GO:0047588	5-aminopentanamidase activity	molecular_function	Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.
GO:0047589	5-aminovalerate transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.
GO:0047590	5-dehydro-2-deoxygluconokinase activity	molecular_function	Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.
GO:0047591	5-hydroxypentanoate CoA-transferase activity	molecular_function	Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.
GO:0047592	5-pyridoxate dioxygenase activity	molecular_function	Catalysis of the reaction: 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP+.
GO:0047593	6-acetylglucose deacetylase activity	molecular_function	Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate + H+.
GO:0047594	6-beta-hydroxyhyoscyamine epoxidase activity	molecular_function	Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H2O + H+ + scopolamine + succinate.
GO:0047595	6-hydroxynicotinate reductase activity	molecular_function	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.
GO:0047596	6-methylsalicylate decarboxylase activity	molecular_function	Catalysis of the reaction: 6-methylsalicylate + H+ = 3-cresol + CO2.
GO:0047597	6-oxocineole dehydrogenase activity	molecular_function	Catalysis of the reaction: 6-oxocineole + H+ + NADPH + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H2O + NADP+.
GO:0047598	7-dehydrocholesterol reductase activity	molecular_function	Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.
GO:0047599	8-oxocoformycin reductase activity	molecular_function	Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + 2 H+ + NADPH.
GO:0047600	abequosyltransferase activity	molecular_function	Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.
GO:0047601	acetate kinase (diphosphate) activity	molecular_function	Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.
GO:0047602	acetoacetate decarboxylase activity	molecular_function	Catalysis of the reaction: acetoacetate + H+ = acetone + CO2.
GO:0047603	acetoacetyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: acetoacetyl-CoA + H2O = acetoacetate + CoA + H+.
GO:0047604	acetoin racemase activity	molecular_function	Catalysis of the reaction: (S)-acetoin = (R)-acetoin.
GO:0047605	acetolactate decarboxylase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.
GO:0047606	hydroxynitrilase activity	molecular_function	Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.
GO:0047608	acetylindoxyl oxidase activity	molecular_function	Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.
GO:0047609	acetylputrescine deacetylase activity	molecular_function	Catalysis of the reaction: N-acetylputrescine + H2O = acetate + putrescine.
GO:0047610	acetylsalicylate deacetylase activity	molecular_function	Catalysis of the reaction: acetylsalicylate + H2O = acetate + H+ + salicylate.
GO:0047611	acetylspermidine deacetylase activity	molecular_function	Catalysis of the reaction: N(8)-acetylspermidine + H2O = acetate + spermidine.
GO:0047612	acid-CoA ligase (GDP-forming) activity	molecular_function	Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H+ + phosphate.
GO:0047613	aconitate decarboxylase activity	molecular_function	Catalysis of the reaction: cis-aconitate + H+ = CO2 + itaconate.
GO:0047614	aconitate delta-isomerase activity	molecular_function	Catalysis of the reaction: trans-aconitate = cis-aconitate.
GO:0047615	actinomycin lactonase activity	molecular_function	Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.
GO:0047616	acyl-CoA dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.
GO:0047617	acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.
GO:0047618	acylagmatine amidase activity	molecular_function	Catalysis of the reaction: N(4)-benzoylagmatine + H2O = agmatine + benzoate.
GO:0047619	acylcarnitine hydrolase activity	molecular_function	Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.
GO:0047620	acylglycerol kinase activity	molecular_function	Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.
GO:0047621	acylpyruvate hydrolase activity	molecular_function	Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.
GO:0047622	adenosine nucleosidase activity	molecular_function	Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.
GO:0047623	adenosine-phosphate deaminase activity	molecular_function	Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.
GO:0047624	adenosine-tetraphosphatase activity	molecular_function	Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.
GO:0047625	adenosylmethionine cyclotransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.
GO:0047627	adenylylsulfatase activity	molecular_function	Catalysis of the reaction: 5'-adenylyl sulfate + H2O = AMP + 2 H+ + sulfate.
GO:0047628	ADP-thymidine kinase activity	molecular_function	Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.
GO:0047629	ADP deaminase activity	molecular_function	Catalysis of the reaction: ADP + H2O = IDP + NH3.
GO:0047630	ADP-phosphoglycerate phosphatase activity	molecular_function	Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H2O = 3-ADP-glycerate + phosphate.
GO:0047631	ADP-ribose diphosphatase activity	molecular_function	Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
GO:0047632	agmatine deiminase activity	molecular_function	Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.
GO:0047633	agmatine kinase activity	molecular_function	Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H+.
GO:0047634	agmatine N4-coumaroyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H+.
GO:0047635	alanine-oxo-acid transaminase activity	molecular_function	Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.
GO:0047636	alanopine dehydrogenase activity	molecular_function	Catalysis of the reaction: 2,2'-iminodipropanoate + H2O + NAD+ = L-alanine + H+ + NADH + pyruvate.
GO:0047637	phosphatidylglycerol alanyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala).
GO:0047638	albendazole monooxygenase activity	molecular_function	Catalysis of the reaction: albendazole + H+ + NADPH + O2 = albendazole S-oxide + H2O + NADP+.
GO:0047639	alcohol oxidase activity	molecular_function	Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.
GO:0047640	aldose 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.
GO:0047641	aldose-6-phosphate reductase (NADPH) activity	molecular_function	Catalysis of the reaction: D-glucitol 6-phosphate + NADP+ = D-glucose 6-phosphate + H+ + NADPH.
GO:0047642	aldose beta-D-fructosyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.
GO:0047643	alginate synthase activity	molecular_function	Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).
GO:0047644	alizarin 2-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H+ + UDP.
GO:0047645	alkan-1-ol dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.
GO:0047646	alkanal monooxygenase (FMN-linked) activity	molecular_function	Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.
GO:0047647	alkylacetylglycerophosphatase activity	molecular_function	Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H2O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.
GO:0047648	alkylamidase activity	molecular_function	Catalysis of the reaction: N-methylhexanamide + H2O = hexanoate + methylammonium.
GO:0047649	alkylglycerol kinase activity	molecular_function	Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H+.
GO:0047650	alkylglycerone kinase activity	molecular_function	Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H+.
GO:0047651	alkylhalidase activity	molecular_function	Catalysis of the reaction: bromochloromethane + H2O = bromide + chloride + formaldehyde + 2 H+.
GO:0047652	allantoate deiminase activity	molecular_function	Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.
GO:0047653	allantoin racemase activity	molecular_function	Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.
GO:0047654	alliin lyase activity	molecular_function	Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.
GO:0047655	allyl-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + H+ + NADPH.
GO:0047656	alpha,alpha-trehalose phosphorylase activity	molecular_function	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
GO:0047657	alpha-1,3-glucan synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.
GO:0047658	alpha-amino-acid esterase activity	molecular_function	Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.
GO:0047659	alpha-santonin 1,2-reductase activity	molecular_function	Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.
GO:0047660	amidinoaspartase activity	molecular_function	Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea.
GO:0047661	amino-acid racemase activity	molecular_function	Catalysis of the reaction: an L-amino acid = a D-amino acid.
GO:0047662	aminobenzoate decarboxylase activity	molecular_function	Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.
GO:0047663	aminoglycoside 6'-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H+. This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.
GO:0047664	aminoimidazolase activity	molecular_function	Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH3.
GO:0047665	aminolevulinate transaminase activity	molecular_function	Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.
GO:0047666	ammonia kinase activity	molecular_function	Catalysis of the reaction: ATP + NH4 = ADP + 3 H+ + phosphoramidate.
GO:0047667	AMP-thymidine kinase activity	molecular_function	Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.
GO:0047668	amygdalin beta-glucosidase activity	molecular_function	Catalysis of the reaction: (R)-amygdalin + H2O = (R)-prunasin + D-glucose.
GO:0047669	amylosucrase activity	molecular_function	Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).
GO:0047670	anhydrotetracycline monooxygenase activity	molecular_function	Catalysis of the reaction: anhydrotetracycline + H+ + NADPH + O2 = 12-dehydrotetracycline + H2O + NADP+.
GO:0047671	anthranilate adenylyltransferase activity	molecular_function	Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H+.
GO:0047672	anthranilate N-benzoyltransferase activity	molecular_function	Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.
GO:0047673	anthranilate N-malonyltransferase activity	molecular_function	Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.
GO:0047674	apiose 1-reductase activity	molecular_function	Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.
GO:0047675	arabinonate dehydratase activity	molecular_function	Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.
GO:0047676	arachidonate-CoA ligase activity	molecular_function	Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H+.
GO:0047677	arachidonate 8(R)-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
GO:0047678	arginine 2-monooxygenase activity	molecular_function	Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O.
GO:0047679	arginine racemase activity	molecular_function	Catalysis of the reaction: L-arginine = D-arginine.
GO:0047680	aryl-acylamidase activity	molecular_function	Catalysis of the reaction: anilide + H2O = a carboxylate + aniline + H+.
GO:0047681	aryl-alcohol dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.
GO:0047682	aryl-alcohol oxidase activity	molecular_function	Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.
GO:0047683	aryl-aldehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.
GO:0047684	arylamine glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.
GO:0047685	amine sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.
GO:0047686	arylsulfate sulfotransferase activity	molecular_function	Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.
GO:0047688	aspartate 4-decarboxylase activity	molecular_function	Catalysis of the reaction: L-aspartate = L-alanine + CO2.
GO:0047689	aspartate racemase activity	molecular_function	Catalysis of the reaction: L-aspartate = D-aspartate.
GO:0047691	aspulvinone dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.
GO:0047692	ATP deaminase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ITP + NH3.
GO:0047693	ATP diphosphatase activity	molecular_function	Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate.
GO:0047694	barbiturase activity	molecular_function	Catalysis of the reaction: barbiturate + H2O = malonate + urea.
GO:0047695	benzoin aldolase activity	molecular_function	Catalysis of the reaction: benzoin = 2 benzaldehyde.
GO:0047696	beta-adrenergic receptor kinase activity	molecular_function	Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor.
GO:0047697	beta-alanopine dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-beta-alanopine + H2O + NAD+ = beta-alanine + H+ + NADH + pyruvate.
GO:0047698	beta-alanyl-CoA ammonia-lyase activity	molecular_function	Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.
GO:0047699	beta-diketone hydrolase activity	molecular_function	Catalysis of the reaction: H2O + nonane-4,6-dione = butanoate + H+ + pentan-2-one.
GO:0047700	beta-glucoside kinase activity	molecular_function	Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.
GO:0047701	beta-L-arabinosidase activity	molecular_function	Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.
GO:0047702	beta-lysine 5,6-aminomutase activity	molecular_function	Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.
GO:0047703	beta-nitroacrylate reductase activity	molecular_function	Catalysis of the reaction: 3-nitropropanoate + NADP+ = 3-nitroacrylate + H+ + NADPH.
GO:0047704	bile-salt sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.
GO:0047705	bilirubin oxidase activity	molecular_function	Catalysis of the reaction: 2 bilirubin + O2 = 2 biliverdin + 2 H2O.
GO:0047706	biochanin-A reductase activity	molecular_function	Catalysis of the reaction: dihydrobiochanin A + NADP+ = biochanin A + H+ + NADPH.
GO:0047707	biotin-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.
GO:0047708	biotinidase activity	molecular_function	Catalysis of the reaction: biotin amide + H2O = biotin + NH3.
GO:0047709	bis(2-ethylhexyl)phthalate esterase activity	molecular_function	Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H+.
GO:0047710	bis(5'-adenosyl)-triphosphatase activity	molecular_function	Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP + 2 H+.
GO:0047711	blasticidin-S deaminase activity	molecular_function	Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.
GO:0047712	Cypridina-luciferin 2-monooxygenase activity	molecular_function	Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.
GO:0047713	galactitol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: galactitol + NAD+ = D-tagatose + H+ + NADH.
GO:0047714	galactolipase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.
GO:0047715	hypotaurocyamine kinase activity	molecular_function	Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H+.
GO:0047716	imidazole N-acetyltransferase activity	molecular_function	Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.
GO:0047717	imidazoleacetate 4-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + imidazol-4-ylacetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD+.
GO:0047718	indanol dehydrogenase activity	molecular_function	Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.
GO:0047719	indole 2,3-dioxygenase activity	molecular_function	Catalysis of the reaction: indole + O2 = 2-formamidobenzaldehyde.
GO:0047720	indoleacetaldoxime dehydratase activity	molecular_function	Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O.
GO:0047721	indoleacetate-lysine synthetase activity	molecular_function	Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H+ + phosphate.
GO:0047722	indolelactate dehydrogenase (NADH) activity	molecular_function	Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD+ = 3-(indol-3-yl)pyruvate + H+ + NADH.
GO:0047723	inosinate nucleosidase activity	molecular_function	Catalysis of the reaction: H2O + IMP = D-ribose 5-phosphate + hypoxanthine.
GO:0047724	inosine nucleosidase activity	molecular_function	Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.
GO:0047725	inulosucrase activity	molecular_function	Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).
GO:0047726	iron-cytochrome-c reductase activity	molecular_function	Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.
GO:0047727	isobutyryl-CoA mutase activity	molecular_function	Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.
GO:0047728	carnitine 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.
GO:0047729	carnitine decarboxylase activity	molecular_function	Catalysis of the reaction: carnitine + H+ = 2-methylcholine + CO2.
GO:0047730	carnosine synthase activity	molecular_function	Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.
GO:0047731	catechol oxidase (dimerizing) activity	molecular_function	Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.
GO:0047732	CDP-abequose epimerase activity	molecular_function	Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.
GO:0047733	CDP-glucose 4,6-dehydratase activity	molecular_function	Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O.
GO:0047734	CDP-glycerol diphosphatase activity	molecular_function	Catalysis of the reaction: CDP-glycerol + H2O = sn-glycerol 3-phosphate + CMP + 2 H+.
GO:0047735	cellobiose dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.
GO:0047736	cellobiose epimerase activity	molecular_function	Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.
GO:0047738	cellobiose phosphorylase activity	molecular_function	Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.
GO:0047739	cephalosporin-C deacetylase activity	molecular_function	Catalysis of the reaction: cephalosporin C + H2O = acetate + deacetylcephalosporin C + H+.
GO:0047740	cephalosporin-C transaminase activity	molecular_function	Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.
GO:0047741	cetraxate benzylesterase activity	molecular_function	Catalysis of the reaction: benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+.
GO:0047742	chenodeoxycholoyltaurine hydrolase activity	molecular_function	Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.
GO:0047743	chlordecone reductase activity	molecular_function	Catalysis of the reaction: chlordecone alcohol + NADP+ = chlordecone + H+ + NADPH.
GO:0047744	chloridazon-catechol dioxygenase activity	molecular_function	Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H+.
GO:0047745	chlorogenate hydrolase activity	molecular_function	Catalysis of the reaction: chlorogenate + H2O = (-)-quinate + cis-caffeate + H+.
GO:0047746	chlorophyllase activity	molecular_function	Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.
GO:0047747	cholate-CoA ligase activity	molecular_function	Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA.
GO:0047748	cholestanetetraol 26-dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.
GO:0047749	cholestanetriol 26-monooxygenase activity	molecular_function	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.
GO:0047750	cholestenol delta-isomerase activity	molecular_function	Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.
GO:0047751	3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)	molecular_function	Catalysis of the reaction: 3-oxo-5alpha-steroid + NADP+ = a 3-oxo-delta(4)-steroid + H+ + NADPH.
GO:0047753	choline-sulfatase activity	molecular_function	Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.
GO:0047754	choline sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H+.
GO:0047755	isocitrate epimerase activity	molecular_function	Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.
GO:0047756	chondroitin 4-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.
GO:0047757	chondroitin-glucuronate 5-epimerase activity	molecular_function	Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.
GO:0047758	ATP:2-methylpropanoate phosphotransferase activity	molecular_function	Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H+.
GO:0047759	butanal dehydrogenase activity	molecular_function	Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.
GO:0047760	butyrate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.
GO:0047761	butyrate kinase activity	molecular_function	Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H+.
GO:0047762	caffeate 3,4-dioxygenase activity	molecular_function	Catalysis of the reaction: trans-caffeate + O2 = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H+.
GO:0047763	caffeate O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
GO:0047765	caldesmon-phosphatase activity	molecular_function	Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate.
GO:0047766	carbamoyl-serine ammonia-lyase activity	molecular_function	Catalysis of the reaction: O-carbamoyl-L-serine + H2O + H+ = CO2 + 2 NH4 + pyruvate.
GO:0047768	carboxy-cis,cis-muconate cyclase activity	molecular_function	Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.
GO:0047769	arogenate dehydratase activity	molecular_function	Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.
GO:0047770	carboxylate reductase activity	molecular_function	Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.
GO:0047771	carboxymethylhydantoinase activity	molecular_function	Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H+.
GO:0047772	carboxymethyloxysuccinate lyase activity	molecular_function	Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.
GO:0047773	carnitinamidase activity	molecular_function	Catalysis of the reaction: (R)-carnitinamide + H2O = (R)-carnitine + NH4.
GO:0047774	cis-2-enoyl-CoA reductase (NADPH) activity	molecular_function	Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.
GO:0047775	citramalate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.
GO:0047776	citramalate lyase activity	molecular_function	Catalysis of the reaction: S-citramalate = acetate + pyruvate.
GO:0047777	(S)-citramalyl-CoA lyase activity	molecular_function	Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.
GO:0047778	[citrate-(pro-3S)-lyase] thiolesterase activity	molecular_function	Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.
GO:0047779	citrate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.
GO:0047780	citrate dehydratase activity	molecular_function	Catalysis of the reaction: citrate = cis-aconitate + H2O.
GO:0047781	citrullinase activity	molecular_function	Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine.
GO:0047782	coniferin beta-glucosidase activity	molecular_function	Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.
GO:0047783	corticosterone 18-monooxygenase activity	molecular_function	Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.
GO:0047784	cortisol O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.
GO:0047785	cortisol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H+.
GO:0047787	delta4-3-oxosteroid 5beta-reductase activity	molecular_function	Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+.
GO:0047788	2-coumarate reductase activity	molecular_function	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD+ = trans-2-coumarate + H+ + NADH.
GO:0047789	creatininase activity	molecular_function	Catalysis of the reaction: creatinine + H2O = creatine.
GO:0047790	creatinine deaminase activity	molecular_function	Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.
GO:0047791	cucurbitacin delta23-reductase activity	molecular_function	Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+.
GO:0047792	cyanohydrin beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.
GO:0047793	cycloeucalenol cycloisomerase activity	molecular_function	Catalysis of the reaction: cycloeucalenol = obtusifoliol.
GO:0047794	cyclohexadienyl dehydrogenase activity	molecular_function	Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.
GO:0047795	cyclohexane-1,2-diol dehydrogenase activity	molecular_function	Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.
GO:0047796	cyclohexane-1,3-dione hydrolase activity	molecular_function	Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate + H+.
GO:0047797	cyclohexanone dehydrogenase activity	molecular_function	Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.
GO:0047798	cyclomaltodextrinase activity	molecular_function	Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.
GO:0047799	cyclopentanone monooxygenase activity	molecular_function	Catalysis of the reaction: cyclopentanone + H+ + NADPH + O2 = 5-valerolactone + H2O + NADP+.
GO:0047800	cysteamine dioxygenase activity	molecular_function	Catalysis of the reaction: cysteamine + O2 = H+ + hypotaurine.
GO:0047801	L-cysteine transaminase activity	molecular_function	Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
GO:0047802	cysteine-conjugate transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.
GO:0047803	cysteine lyase activity	molecular_function	Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.
GO:0047804	cysteine-S-conjugate beta-lyase activity	molecular_function	Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.
GO:0047805	cytidylate cyclase activity	molecular_function	Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.
GO:0047806	cytochrome-c3 hydrogenase activity	molecular_function	Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.
GO:0047807	cytokinin 7-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.
GO:0047808	D(-)-tartrate dehydratase activity	molecular_function	Catalysis of the reaction: D-tartrate = H2O + oxaloacetate.
GO:0047809	D-2-hydroxy-acid dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.
GO:0047810	D-alanine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.
GO:0047811	D-alanine gamma-glutamyltransferase activity	molecular_function	Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4.
GO:0047812	D-amino-acid N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.
GO:0047813	D-arabinitol 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.
GO:0047814	D-arabinokinase activity	molecular_function	Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.
GO:0047815	D-arabinonolactonase activity	molecular_function	Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate + H+.
GO:0047816	D-arabinose 1-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.
GO:0047817	D-arginase activity	molecular_function	Catalysis of the reaction: D-arginine + H2O = D-ornithine + urea.
GO:0047818	D-fuconate dehydratase activity	molecular_function	Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O.
GO:0047819	D-glutamate(D-aspartate) oxidase activity	molecular_function	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.
GO:0047820	D-glutamate cyclase activity	molecular_function	Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O.
GO:0047821	D-glutamate oxidase activity	molecular_function	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.
GO:0047822	hypotaurine dehydrogenase activity	molecular_function	Catalysis of the reaction: H+ + hypotaurine + NADPH + O2 = H2O + NADP+ + taurine.
GO:0047823	D-glutamyltransferase activity	molecular_function	Catalysis of the reaction:  D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.
GO:0047824	D-iditol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.
GO:0047825	D-lactate-2-sulfatase activity	molecular_function	Catalysis of the reaction: (R)-2-O-sulfolactate + H2O = (R)-lactate + H+ + sulfate.
GO:0047826	D-lysine 5,6-aminomutase activity	molecular_function	Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate.
GO:0047827	D-lysopine dehydrogenase activity	molecular_function	Catalysis of the reaction: D-lysopine + H2O + NADP+ = L-lysine + H+ + NADPH + pyruvate.
GO:0047828	D-lyxose ketol-isomerase activity	molecular_function	Catalysis of the reaction: D-lyxose = D-xylulose.
GO:0047829	D-nopaline dehydrogenase activity	molecular_function	Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.
GO:0047830	D-octopine dehydrogenase activity	molecular_function	Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.
GO:0047831	D-ornithine 4,5-aminomutase activity	molecular_function	Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.
GO:0047832	D-pinitol dehydrogenase activity	molecular_function	Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADPH.
GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.
GO:0047834	D-threo-aldose 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.
GO:0047835	D-tryptophan N-acetyltransferase activity	molecular_function	Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H+.
GO:0047836	D-tryptophan N-malonyltransferase activity	molecular_function	Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H+.
GO:0047837	D-xylose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-xylose + NADP+ = D-xylono-1,5-lactone + H+ + NADPH.
GO:0047838	D-xylose 1-dehydrogenase (NAD) activity	molecular_function	Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.
GO:0047839	dATP(dGTP)-DNA purinetransferase activity	molecular_function	Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.
GO:0047840	dCTP diphosphatase activity	molecular_function	Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.
GO:0047841	dehydrogluconokinase activity	molecular_function	Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H+.
GO:0047842	dehydro-L-gulonate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-dehydro-L-gulonate + H+ = L-xylulose + CO2.
GO:0047843	dehydrogluconate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).
GO:0047844	deoxycytidine deaminase activity	molecular_function	Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
GO:0047845	deoxylimonate A-ring-lactonase activity	molecular_function	Catalysis of the reaction: deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H+.
GO:0047846	deoxynucleotide 3'-phosphatase activity	molecular_function	Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.
GO:0047847	deoxyuridine phosphorylase activity	molecular_function	Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
GO:0047848	dephospho-[reductase kinase] kinase activity	molecular_function	Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].
GO:0047849	dextransucrase activity	molecular_function	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).
GO:0047850	diaminopimelate dehydrogenase activity	molecular_function	Catalysis of the reaction: meso-2,6-diaminopimelate + H2O + NADP+ = L-2-amino-6-oxopimelate + H+ + NADPH + NH4.
GO:0047851	dicarboxylate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA.
GO:0047852	diferric-transferrin reductase activity	molecular_function	Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.
GO:0047853	difructose-anhydride synthase activity	molecular_function	Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.
GO:0047854	diguanidinobutanase activity	molecular_function	Catalysis of the reaction: 1,4-diguanidinobutane + H2O = agmatine + urea.
GO:0047855	dihydrobunolol dehydrogenase activity	molecular_function	Catalysis of the reaction: dihydrobunolol + NADP+ = bunolol + H+ + NADPH.
GO:0047856	dihydrocoumarin hydrolase activity	molecular_function	Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.
GO:0047857	dihydrouracil oxidase activity	molecular_function	Catalysis of the reaction: 5,6-dihydrouracil + O2 = H2O2 + uracil.
GO:0047858	dihydroxyfumarate decarboxylase activity	molecular_function	Catalysis of the reaction: dihydroxyfumarate + H+ = 2-hydroxy-3-oxopropanoate + CO2.
GO:0047860	diiodophenylpyruvate reductase activity	molecular_function	Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H+ + NADH.
GO:0047861	diiodotyrosine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.
GO:0047862	diisopropyl-fluorophosphatase activity	molecular_function	Catalysis of the reaction: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + 2 H+ + hydrogen fluoride.
GO:0047863	dimethylallylcistransferase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.
GO:0047864	dimethylaniline-N-oxide aldolase activity	molecular_function	Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.
GO:0047865	dimethylglycine dehydrogenase activity	molecular_function	Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.
GO:0047866	dimethylglycine oxidase activity	molecular_function	Catalysis of the reaction: N,N-dimethylglycine + H2O + O2 = formaldehyde + H2O2 + sarcosine.
GO:0047867	dimethylmalate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH.
GO:0047868	dimethylmaleate hydratase activity	molecular_function	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O.
GO:0047869	dimethylpropiothetin dethiomethylase activity	molecular_function	Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H+.
GO:0047870	discadenine synthase activity	molecular_function	Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H+.
GO:0047871	disulfoglucosamine-6-sulfatase activity	molecular_function	Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + H+ + sulfate.
GO:0047872	dolichol O-acyltransferase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.
GO:0047873	dolichyl-phosphatase activity	molecular_function	Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.
GO:0047874	dolichyldiphosphatase activity	molecular_function	Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.
GO:0047875	ecdysone oxidase activity	molecular_function	Catalysis of the reaction: Ecdysone + O2 = 3-dehydroecdysone + H2O2.
GO:0047876	endoglycosylceramidase activity	molecular_function	Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.
GO:0047877	ephedrine dehydrogenase activity	molecular_function	Catalysis of the reaction: (1R,2S)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H+ + NADH.
GO:0047878	erythritol kinase activity	molecular_function	Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H+.
GO:0047879	erythronolide synthase activity	molecular_function	Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.
GO:0047880	erythrulose reductase activity	molecular_function	Catalysis of the reaction: D-threitol + NADP+ = D-erythrulose + H+ + NADPH.
GO:0047881	estradiol 17-alpha-dehydrogenase activity	molecular_function	Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.
GO:0047882	estradiol 6-beta-monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + estradiol-17beta + O2 = 6beta-hydroxyestradiol-17beta + A + H2O.
GO:0047883	ethanolamine oxidase activity	molecular_function	Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.
GO:0047884	FAD diphosphatase activity	molecular_function	Catalysis of the reaction: FAD + H2O = AMP + FMN.
GO:0047885	farnesol 2-isomerase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.
GO:0047886	farnesol dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + H+ + NADPH.
GO:0047887	farnesyl diphosphate kinase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.
GO:0047888	fatty acid peroxidase activity	molecular_function	Catalysis of the reaction: 2 H2O2 + H+ + palmitate = CO2 + 3 H2O + pentadecanal.
GO:0047889	ferredoxin-nitrate reductase activity	molecular_function	Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.
GO:0047890	flavanone 4-reductase activity	molecular_function	Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.
GO:0047891	flavone 7-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.
GO:0047892	flavone apiosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.
GO:0047893	flavonol 3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.
GO:0047894	flavonol 3-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H+ + quercetin 3-sulfate.
GO:0047895	formaldehyde dismutase activity	molecular_function	Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.
GO:0047896	formaldehyde transketolase activity	molecular_function	Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.
GO:0047897	formate-dihydrofolate ligase activity	molecular_function	Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H+ + phosphate.
GO:0047898	formate dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.
GO:0047899	formate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: formate + NADP+ = CO2 + NADPH.
GO:0047900	formate kinase activity	molecular_function	Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H+.
GO:0047901	formyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: formyl-CoA + H2O = CoA + formate + H+.
GO:0047902	formylaspartate deformylase activity	molecular_function	Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.
GO:0047903	fructose 5-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.
GO:0047904	fructose 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2).
GO:0047905	fructose-6-phosphate phosphoketolase activity	molecular_function	Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.
GO:0047906	fucosterol-epoxide lyase activity	molecular_function	Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.
GO:0047907	furylfuramide isomerase activity	molecular_function	Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.
GO:0047908	fusarinine-C ornithinesterase activity	molecular_function	Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.
GO:0047909	galactolipid O-acyltransferase activity	molecular_function	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.
GO:0047910	galactose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.
GO:0047911	galacturan 1,4-alpha-galacturonidase activity	molecular_function	Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.
GO:0047912	galacturonokinase activity	molecular_function	Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.
GO:0047913	gallate 1-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.
GO:0047914	gamma-glutamylhistamine synthase activity	molecular_function	Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.
GO:0047915	ganglioside galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.
GO:0047916	GDP-6-deoxy-D-talose 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.
GO:0047917	GDP-glucosidase activity	molecular_function	Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.
GO:0047918	GDP-mannose 3,5-epimerase activity	molecular_function	Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
GO:0047919	GDP-mannose 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose + H2O + 2 NAD+ = GDP-D-mannuronate + 3 H+ + 2 NADH.
GO:0047920	geissoschizine dehydrogenase activity	molecular_function	Catalysis of the reaction: geissoschizine + NADP+ = 4,21-dehydrogeissoschizine + H+ + NADPH.
GO:0047921	aminoglycoside 2'-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.
GO:0047922	gentisate 1,2-dioxygenase activity	molecular_function	Catalysis of the reaction: 2,5-dihydroxybenzoate + O2 = 3-maleylpyruvate + H+.
GO:0047923	gentisate decarboxylase activity	molecular_function	Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.
GO:0047924	geraniol dehydrogenase activity	molecular_function	Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.
GO:0047925	geranoyl-CoA carboxylase activity	molecular_function	Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H+ + phosphate.
GO:0047926	geranyl-diphosphate cyclase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.
GO:0047927	gibberellin-44 dioxygenase activity	molecular_function	Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.
GO:0047928	gibberellin beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.
GO:0047929	gluconate dehydratase activity	molecular_function	Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.
GO:0047930	glucosaminate ammonia-lyase activity	molecular_function	Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.
GO:0047931	glucosamine kinase activity	molecular_function	Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate.
GO:0047932	glucosamine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.
GO:0047933	glucose-1,6-bisphosphate synthase activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H+.
GO:0047934	glucose 1-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.
GO:0047935	glucose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.
GO:0047936	glucose 1-dehydrogenase [NAD(P)] activity	molecular_function	Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.
GO:0047937	glucose-1-phosphate phosphodismutase activity	molecular_function	Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.
GO:0047938	glucose-6-phosphate 1-epimerase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.
GO:0047939	L-glucuronate reductase activity	molecular_function	Catalysis of the reaction: L-gulonate + NADP+ = D-glucuronate + H+ + NADPH.
GO:0047940	glucuronokinase activity	molecular_function	Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H+.
GO:0047941	glucuronolactone reductase activity	molecular_function	Catalysis of the reaction: L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + H+ + NADPH.
GO:0047942	glutamate-ethylamine ligase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H+ + phosphate.
GO:0047943	glutamate-methylamine ligase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H+ + phosphate.
GO:0047945	L-glutamine:pyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.
GO:0047946	glutamine N-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.
GO:0047947	glutamine N-phenylacetyltransferase activity	molecular_function	Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.
GO:0047948	glutarate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H+ + phosphate.
GO:0047950	glutathione oxidase activity	molecular_function	Catalysis of the reaction: 2 glutathione + O2 = glutathione disulfide + H2O2.
GO:0047951	glutathione thiolesterase activity	molecular_function	Catalysis of the reaction: S-acylglutathione + H2O = a carboxylate + glutathione + H+.
GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.
GO:0047953	glycerol 2-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: glycerol + NADP+ = glycerone + H+ + NADPH.
GO:0047954	glycerol-2-phosphatase activity	molecular_function	Catalysis of the reaction: glycerol 2-phosphate + H2O = glycerol + phosphate.
GO:0047955	glycerol dehydrogenase (acceptor) activity	molecular_function	Catalysis of the reaction: A + glycerol = AH(2) + glycerone.
GO:0047956	glycerol dehydrogenase [NADP+] activity	molecular_function	Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.
GO:0047957	4'-methoxyisoflavone 2'-hydroxylase activity	molecular_function	Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O.
GO:0047958	glycine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.
GO:0047959	glycine dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.
GO:0047960	glycine dehydrogenase activity	molecular_function	Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.
GO:0047961	glycine N-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine.
GO:0047962	glycine N-benzoyltransferase activity	molecular_function	Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H+.
GO:0047963	glycine N-choloyltransferase activity	molecular_function	Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate.
GO:0047964	glyoxylate reductase (NAD+) activity	molecular_function	Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.
GO:0047965	glycoprotein O-fatty-acyltransferase activity	molecular_function	Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.
GO:0047966	glycosulfatase activity	molecular_function	Catalysis of the reaction: D-glucose 6-sulfate + H2O = D-glucose + H+ + sulfate.
GO:0047967	glycyrrhizinate beta-glucuronidase activity	molecular_function	Catalysis of the reaction: glycyrrhizate + H2O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.
GO:0047968	glyoxylate dehydrogenase (acylating) activity	molecular_function	Catalysis of the reaction: CoA + glyoxylate + NADP+ = H+ + NADPH + oxalyl-CoA.
GO:0047969	glyoxylate oxidase activity	molecular_function	Catalysis of the reaction: glyoxylate + H2O + O2 = H2O2 + H+ + oxalate.
GO:0047970	guanidinoacetase activity	molecular_function	Catalysis of the reaction: guanidinoacetate + H2O = glycine + urea.
GO:0047971	guanidinobutyrase activity	molecular_function	Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.
GO:0047972	guanidinopropionase activity	molecular_function	Catalysis of the reaction: 3-guanidinopropanoate + H2O = beta-alanine + urea.
GO:0047973	guanidinoacetate kinase activity	molecular_function	Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H+ + phosphoguanidinoacetate.
GO:0047974	guanosine deaminase activity	molecular_function	Catalysis of the reaction: guanosine + H2O = xanthosine + NH3.
GO:0047975	guanosine phosphorylase activity	molecular_function	Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate.
GO:0047976	hamamelose kinase activity	molecular_function	Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H+.
GO:0047977	hepoxilin-epoxide hydrolase activity	molecular_function	Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.
GO:0047978	hexadecanol dehydrogenase activity	molecular_function	Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.
GO:0047979	hexose oxidase activity	molecular_function	Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.
GO:0047980	hippurate hydrolase activity	molecular_function	Catalysis of the reaction: N-benzoylglycine + H2O = benzoate + glycine.
GO:0047981	histidine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.
GO:0047982	homocysteine desulfhydrase activity	molecular_function	Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate.
GO:0047983	homoglutathione synthase activity	molecular_function	Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H+ + phosphate.
GO:0047985	hydrogen dehydrogenase activity	molecular_function	Catalysis of the reaction: H2 + NAD+ = H+ + NADH.
GO:0047986	hydrogen-sulfide S-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.
GO:0047988	hydroxyacid-oxoacid transhydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
GO:0047989	hydroxybutyrate-dimer hydrolase activity	molecular_function	Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H2O = 2 (R)-3-hydroxybutanoate + H+.
GO:0047990	hydroxyglutamate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-L-glutamate + H+ = 4-amino-3-hydroxybutanoate + CO2.
GO:0047991	hydroxylamine oxidase activity	molecular_function	Catalysis of the reaction: hydroxylamine + O2 = H2O + H+ + nitrite.
GO:0047992	hydroxylysine kinase activity	molecular_function	Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H+.
GO:0047993	hydroxymalonate dehydrogenase activity	molecular_function	Catalysis of the reaction: hydroxymalonate + NAD+ = H+ + NADH + oxomalonate.
GO:0047994	hydroxymethylglutaryl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H+.
GO:0047995	hydroxyphenylpyruvate reductase activity	molecular_function	Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH.
GO:0047996	hydroxyphytanate oxidase activity	molecular_function	Catalysis of the reaction: (2S)-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2.
GO:0047997	hydroxypyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-hydroxypyruvate + H+ = CO2 + glycolaldehyde.
GO:0047998	hyoscyamine (6S)-dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate.
GO:0047999	hyponitrite reductase activity	molecular_function	Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = 2 H+ + hyponitrous acid + 2 NADH.
GO:0048000	isoflavone 3'-hydroxylase activity	molecular_function	Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.
GO:0048001	erythrose-4-phosphate dehydrogenase activity	molecular_function	Catalysis of the reaction: D-erythrose 4-phosphate + H2O + NAD+ = 4-phospho-D-erythronate + 2 H+ + NADH.
GO:0048002	antigen processing and presentation of peptide antigen	biological_process	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
GO:0048006	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	biological_process	The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
GO:0048008	platelet-derived growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048009	insulin-like growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048010	vascular endothelial growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048011	neurotrophin TRK receptor signaling pathway	biological_process	The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048012	hepatocyte growth factor receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048013	ephrin receptor signaling pathway	biological_process	The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048014	Tie signaling pathway	biological_process	The series of molecular signals initiated by an angiopoietin binding to the Tie receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048015	phosphatidylinositol-mediated signaling	biological_process	The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
GO:0048018	receptor ligand activity	molecular_function	The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
GO:0048019	receptor antagonist activity	molecular_function	The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
GO:0048020	CCR chemokine receptor binding	molecular_function	Binding to a CCR chemokine receptor.
GO:0048021	regulation of melanin biosynthetic process	biological_process	Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
GO:0048022	negative regulation of melanin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
GO:0048023	positive regulation of melanin biosynthetic process	biological_process	Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
GO:0048024	regulation of mRNA splicing, via spliceosome	biological_process	Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
GO:0048025	negative regulation of mRNA splicing, via spliceosome	biological_process	Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
GO:0048026	positive regulation of mRNA splicing, via spliceosome	biological_process	Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
GO:0048027	mRNA 5'-UTR binding	molecular_function	Binding to an mRNA molecule at its 5' untranslated region.
GO:0048028	galacturonan binding	molecular_function	Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.
GO:0048029	monosaccharide binding	molecular_function	Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
GO:0048030	disaccharide binding	molecular_function	Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units.
GO:0048031	trisaccharide binding	molecular_function	Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.
GO:0048032	galacturonate binding	molecular_function	Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
GO:0048033	heme O metabolic process	biological_process	The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
GO:0048034	heme O biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
GO:0048035	heme O catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
GO:0048036	central complex development	biological_process	The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.
GO:0048038	quinone binding	molecular_function	Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
GO:0048039	ubiquinone binding	molecular_function	Binding to ubiquinone, a quinone derivative with a tail of isoprene units.
GO:0048040	UDP-glucuronate decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = CO2 + UDP-alpha-D-xylose.
GO:0048041	focal adhesion assembly	biological_process	The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
GO:0048046	apoplast	cellular_component	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
GO:0048047	mating behavior, sex discrimination	biological_process	The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.
GO:0048048	embryonic eye morphogenesis	biological_process	The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
GO:0048050	post-embryonic eye morphogenesis	biological_process	The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.
GO:0048052	R1/R6 cell differentiation	biological_process	The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.
GO:0048053	R1/R6 development	biological_process	The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
GO:0048054	R2/R5 cell differentiation	biological_process	The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.
GO:0048055	R2/R5 development	biological_process	The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
GO:0048056	R3/R4 cell differentiation	biological_process	The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.
GO:0048057	R3/R4 development	biological_process	The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
GO:0048058	compound eye corneal lens development	biological_process	The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.
GO:0048060	negative gravitaxis	biological_process	The directed movement of a motile cell or organism away from the source of gravity.
GO:0048061	positive gravitaxis	biological_process	The directed movement of a motile cell or organism towards the source of gravity.
GO:0048065	male courtship behavior, veined wing extension	biological_process	The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.
GO:0048066	developmental pigmentation	biological_process	The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
GO:0048067	cuticle pigmentation	biological_process	Establishment of a pattern of pigment in the cuticle of an organism.
GO:0048069	eye pigmentation	biological_process	Establishment of a pattern of pigment in the eye of an organism.
GO:0048070	regulation of developmental pigmentation	biological_process	Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
GO:0048071	sex-specific pigmentation	biological_process	Establishment of a pattern of pigment in one sex that is not observed in the other sex.
GO:0048072	compound eye pigmentation	biological_process	Establishment of a pattern of pigment in the compound eye.
GO:0048073	regulation of eye pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
GO:0048074	negative regulation of eye pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
GO:0048075	positive regulation of eye pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
GO:0048076	regulation of compound eye pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
GO:0048077	negative regulation of compound eye pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
GO:0048078	positive regulation of compound eye pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
GO:0048079	regulation of cuticle pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
GO:0048080	negative regulation of cuticle pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
GO:0048081	positive regulation of cuticle pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
GO:0048082	regulation of adult chitin-containing cuticle pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
GO:0048083	negative regulation of adult chitin-containing cuticle pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
GO:0048084	positive regulation of adult chitin-containing cuticle pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
GO:0048085	adult chitin-containing cuticle pigmentation	biological_process	Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.
GO:0048086	negative regulation of developmental pigmentation	biological_process	Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
GO:0048087	positive regulation of developmental pigmentation	biological_process	Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
GO:0048088	regulation of male pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.
GO:0048089	regulation of female pigmentation	biological_process	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.
GO:0048090	negative regulation of female pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.
GO:0048091	positive regulation of female pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.
GO:0048092	negative regulation of male pigmentation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.
GO:0048093	positive regulation of male pigmentation	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.
GO:0048094	male pigmentation	biological_process	Establishment of a pattern of pigment in males.
GO:0048095	female pigmentation	biological_process	Establishment of a pattern of pigment in females.
GO:0048098	antennal joint development	biological_process	The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.
GO:0048099	anterior/posterior lineage restriction, imaginal disc	biological_process	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.
GO:0048100	wing disc anterior/posterior pattern formation	biological_process	The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	molecular_function	Catalysis of the reactions: nucleoside 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
GO:0048102	autophagic cell death	biological_process	A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
GO:0048103	somatic stem cell division	biological_process	The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
GO:0048104	establishment of body hair or bristle planar orientation	biological_process	Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.
GO:0048105	establishment of body hair planar orientation	biological_process	Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.
GO:0048106	establishment of thoracic bristle planar orientation	biological_process	Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.
GO:0048107	4-amino-3-isothiazolidinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.
GO:0048108	peptide cross-linking via 4-amino-3-isothiazolidinone	biological_process	The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.
GO:0048109	peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine	biological_process	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.
GO:0048132	female germ-line stem cell asymmetric division	biological_process	The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
GO:0048133	male germ-line stem cell asymmetric division	biological_process	The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
GO:0048134	germ-line cyst formation	biological_process	Formation of a group of interconnected cells derived from a single gonial founder cell.
GO:0048135	female germ-line cyst formation	biological_process	Formation of a group of interconnected cells derived from a single female gonial founder cell.
GO:0048136	male germ-line cyst formation	biological_process	Formation of a group of interconnected cells derived from a single male gonial founder cell.
GO:0048137	spermatocyte division	biological_process	The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.
GO:0048138	germ-line cyst encapsulation	biological_process	Formation of a single follicular epithelium around the germ-line derived cells of a cyst.
GO:0048139	female germ-line cyst encapsulation	biological_process	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.
GO:0048140	male germ-line cyst encapsulation	biological_process	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.
GO:0048142	germarium-derived cystoblast division	biological_process	The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.
GO:0048143	astrocyte activation	biological_process	A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0048144	fibroblast proliferation	biological_process	The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
GO:0048145	regulation of fibroblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GO:0048146	positive regulation of fibroblast proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GO:0048147	negative regulation of fibroblast proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
GO:0048148	behavioral response to cocaine	biological_process	Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
GO:0048149	behavioral response to ethanol	biological_process	Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
GO:0048150	behavioral response to ether	biological_process	Any process that results in a change in the behavior of an organism as a result of an ether stimulus.
GO:0048156	tau protein binding	molecular_function	Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
GO:0048158	oogonium stage	biological_process	The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.
GO:0048159	primary oocyte stage	biological_process	The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.
GO:0048160	primary follicle stage	biological_process	The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
GO:0048161	double layer follicle stage	biological_process	The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.
GO:0048162	multi-layer follicle stage	biological_process	The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.
GO:0048163	scattered antral spaces stage	biological_process	The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.
GO:0048164	distinct antral spaces stage	biological_process	The stage in oogenesis when the antral spaces become distinct and the first polar body forms.
GO:0048165	fused antrum stage	biological_process	The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.
GO:0048166	mature follicle stage	biological_process	The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.
GO:0048167	regulation of synaptic plasticity	biological_process	A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
GO:0048168	regulation of neuronal synaptic plasticity	biological_process	A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
GO:0048169	regulation of long-term neuronal synaptic plasticity	biological_process	A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	biological_process	A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
GO:0048171	negative regulation of long-term neuronal synaptic plasticity	biological_process	A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
GO:0048172	regulation of short-term neuronal synaptic plasticity	biological_process	A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
GO:0048173	positive regulation of short-term neuronal synaptic plasticity	biological_process	A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
GO:0048174	negative regulation of short-term neuronal synaptic plasticity	biological_process	A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
GO:0048179	activin receptor complex	cellular_component	A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.
GO:0048180	activin complex	cellular_component	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.
GO:0048183	activin AB complex	cellular_component	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.
GO:0048185	activin binding	molecular_function	Binding to activin, a dimer of inhibin-beta subunits.
GO:0048188	Set1C/COMPASS complex	cellular_component	A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
GO:0048189	Lid2 complex	cellular_component	A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1.
GO:0048190	wing disc dorsal/ventral pattern formation	biological_process	The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
GO:0048193	Golgi vesicle transport	biological_process	The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
GO:0048194	Golgi vesicle budding	biological_process	The evagination of the Golgi membrane, resulting in formation of a vesicle.
GO:0048195	Golgi membrane priming complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.
GO:0048197	Golgi membrane coat protein complex assembly	biological_process	The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.
GO:0048198	Golgi vesicle bud deformation and release	biological_process	The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.
GO:0048199	vesicle targeting, to, from or within Golgi	biological_process	The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
GO:0048200	Golgi transport vesicle coating	biological_process	The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.
GO:0048201	vesicle targeting, plasma membrane to endosome	biological_process	The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
GO:0048202	clathrin coating of Golgi vesicle	biological_process	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
GO:0048203	vesicle targeting, trans-Golgi to endosome	biological_process	The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.
GO:0048204	vesicle targeting, inter-Golgi cisterna	biological_process	The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.
GO:0048205	COPI coating of Golgi vesicle	biological_process	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
GO:0048206	vesicle targeting, cis-Golgi to rough endoplasmic reticulum	biological_process	The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.
GO:0048207	vesicle targeting, rough ER to cis-Golgi	biological_process	The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.
GO:0048208	COPII vesicle coating	biological_process	The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
GO:0048209	regulation of vesicle targeting, to, from or within Golgi	biological_process	Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
GO:0048210	Golgi vesicle fusion to target membrane	biological_process	The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.
GO:0048211	Golgi vesicle docking	biological_process	The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.
GO:0048212	Golgi vesicle uncoating	biological_process	The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.
GO:0048213	Golgi vesicle prefusion complex stabilization	biological_process	The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.
GO:0048214	regulation of Golgi vesicle fusion to target membrane	biological_process	Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.
GO:0048215	positive regulation of Golgi vesicle fusion to target membrane	biological_process	Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.
GO:0048216	negative regulation of Golgi vesicle fusion to target membrane	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.
GO:0048217	pectic matrix	cellular_component	The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.
GO:0048219	inter-Golgi cisterna vesicle-mediated transport	biological_process	The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.
GO:0048222	glycoprotein network	cellular_component	An extracellular matrix part that consists of cross-linked glycoproteins.
GO:0048223	hemicellulose network	cellular_component	Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.
GO:0048224	lignin network	cellular_component	An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.
GO:0048225	suberin network	cellular_component	An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.
GO:0048226	Casparian strip	cellular_component	Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.
GO:0048227	plasma membrane to endosome transport	biological_process	Transport of a vesicle from the plasma membrane to the endosome.
GO:0048229	gametophyte development	biological_process	The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.
GO:0048232	male gamete generation	biological_process	Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
GO:0048235	pollen sperm cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
GO:0048236	plant-type sporogenesis	biological_process	The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.
GO:0048237	rough endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the rough endoplasmic reticulum.
GO:0048238	smooth endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the smooth endoplasmic reticulum.
GO:0048239	negative regulation of DNA recombination at telomere	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.
GO:0048240	sperm capacitation	biological_process	A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
GO:0048241	epinephrine transport	biological_process	The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0048242	epinephrine secretion	biological_process	The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
GO:0048243	norepinephrine secretion	biological_process	The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
GO:0048244	phytanoyl-CoA dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.
GO:0048245	eosinophil chemotaxis	biological_process	The movement of an eosinophil in response to an external stimulus.
GO:0048246	macrophage chemotaxis	biological_process	The movement of a macrophage in response to an external stimulus.
GO:0048247	lymphocyte chemotaxis	biological_process	The directed movement of a lymphocyte in response to an external stimulus.
GO:0048248	CXCR3 chemokine receptor binding	molecular_function	Binding to a CXCR3 chemokine receptor.
GO:0048249	high-affinity phosphate transmembrane transporter activity	molecular_function	Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0048250	iron import into the mitochondrion	biological_process	The process in which iron is transported from the cytosol into the mitochondrial matrix.
GO:0048251	elastic fiber assembly	biological_process	Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
GO:0048252	lauric acid metabolic process	biological_process	The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
GO:0048254	snoRNA localization	biological_process	Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.
GO:0048255	mRNA stabilization	biological_process	Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
GO:0048256	flap endonuclease activity	molecular_function	Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.
GO:0048257	3'-flap endonuclease activity	molecular_function	Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.
GO:0048258	3-ketoglucose-reductase activity	molecular_function	Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.
GO:0048259	regulation of receptor-mediated endocytosis	biological_process	Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
GO:0048260	positive regulation of receptor-mediated endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
GO:0048261	negative regulation of receptor-mediated endocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
GO:0048262	determination of dorsal/ventral asymmetry	biological_process	Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.
GO:0048263	determination of dorsal identity	biological_process	Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0048264	determination of ventral identity	biological_process	The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0048265	response to pain	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
GO:0048266	behavioral response to pain	biological_process	Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
GO:0048268	clathrin coat assembly	biological_process	The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
GO:0048269	methionine adenosyltransferase complex	cellular_component	A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
GO:0048270	methionine adenosyltransferase regulator activity	molecular_function	Binds to and modulates the activity of methionine adenosyltransferase.
GO:0048273	mitogen-activated protein kinase p38 binding	molecular_function	Binding to mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.
GO:0048275	N-terminal peptidyl-arginine acetylation	biological_process	The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase.
GO:0048278	vesicle docking	biological_process	The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
GO:0048279	vesicle fusion with endoplasmic reticulum	biological_process	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.
GO:0048280	vesicle fusion with Golgi apparatus	biological_process	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.
GO:0048281	inflorescence morphogenesis	biological_process	The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.
GO:0048282	determinate inflorescence morphogenesis	biological_process	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.
GO:0048283	indeterminate inflorescence morphogenesis	biological_process	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.
GO:0048284	organelle fusion	biological_process	The creation of a single organelle from two or more organelles.
GO:0048285	organelle fission	biological_process	The creation of two or more organelles by division of one organelle.
GO:0048286	lung alveolus development	biological_process	The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
GO:0048288	nuclear membrane fusion involved in karyogamy	biological_process	The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.
GO:0048289	isotype switching to IgE isotypes	biological_process	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
GO:0048290	isotype switching to IgA isotypes	biological_process	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
GO:0048291	isotype switching to IgG isotypes	biological_process	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
GO:0048292	isotype switching to IgD isotypes	biological_process	The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
GO:0048293	regulation of isotype switching to IgE isotypes	biological_process	Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.
GO:0048294	negative regulation of isotype switching to IgE isotypes	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
GO:0048295	positive regulation of isotype switching to IgE isotypes	biological_process	Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
GO:0048296	regulation of isotype switching to IgA isotypes	biological_process	Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.
GO:0048297	negative regulation of isotype switching to IgA isotypes	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.
GO:0048298	positive regulation of isotype switching to IgA isotypes	biological_process	Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
GO:0048299	regulation of isotype switching to IgD isotypes	biological_process	Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.
GO:0048300	negative regulation of isotype switching to IgD isotypes	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.
GO:0048301	positive regulation of isotype switching to IgD isotypes	biological_process	Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.
GO:0048302	regulation of isotype switching to IgG isotypes	biological_process	Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
GO:0048303	negative regulation of isotype switching to IgG isotypes	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.
GO:0048304	positive regulation of isotype switching to IgG isotypes	biological_process	Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
GO:0048306	calcium-dependent protein binding	molecular_function	Binding to a protein or protein complex in the presence of calcium.
GO:0048307	ferredoxin-nitrite reductase activity	molecular_function	Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.
GO:0048308	organelle inheritance	biological_process	The partitioning of organelles between daughter cells at cell division.
GO:0048309	endoplasmic reticulum inheritance	biological_process	The partitioning of endoplasmic reticulum between daughter cells at cell division.
GO:0048311	mitochondrion distribution	biological_process	Any process that establishes the spatial arrangement of mitochondria between and within cells.
GO:0048312	intracellular distribution of mitochondria	biological_process	Any process that establishes the spatial arrangement of mitochondria within the cell.
GO:0048313	Golgi inheritance	biological_process	The partitioning of Golgi apparatus between daughter cells at cell division.
GO:0048314	embryo sac morphogenesis	biological_process	The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.
GO:0048315	conidium formation	biological_process	The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
GO:0048316	seed development	biological_process	The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
GO:0048317	seed morphogenesis	biological_process	The process in which the anatomical structures of the seed are generated and organized.
GO:0048318	axial mesoderm development	biological_process	The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.
GO:0048319	axial mesoderm morphogenesis	biological_process	The process in which the anatomical structures of the axial mesoderm are generated and organized.
GO:0048320	axial mesoderm formation	biological_process	The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
GO:0048321	axial mesodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.
GO:0048322	axial mesodermal cell fate commitment	biological_process	The process in which a cell becomes committed to become an axial mesoderm cell.
GO:0048323	axial mesodermal cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048324	regulation of axial mesodermal cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.
GO:0048325	negative regulation of axial mesodermal cell fate determination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.
GO:0048326	positive regulation of axial mesodermal cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.
GO:0048327	axial mesodermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0048328	regulation of axial mesodermal cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.
GO:0048329	negative regulation of axial mesodermal cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.
GO:0048330	positive regulation of axial mesodermal cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.
GO:0048331	axial mesoderm structural organization	biological_process	The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
GO:0048332	mesoderm morphogenesis	biological_process	The process in which the anatomical structures of the mesoderm are generated and organized.
GO:0048333	mesodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
GO:0048334	regulation of mesodermal cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.
GO:0048335	negative regulation of mesodermal cell fate determination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.
GO:0048336	positive regulation of mesodermal cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.
GO:0048337	positive regulation of mesodermal cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.
GO:0048338	mesoderm structural organization	biological_process	The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.
GO:0048339	paraxial mesoderm development	biological_process	The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
GO:0048340	paraxial mesoderm morphogenesis	biological_process	The process in which the anatomical structures of the paraxial mesoderm are generated and organized.
GO:0048341	paraxial mesoderm formation	biological_process	The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
GO:0048342	paraxial mesodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.
GO:0048343	paraxial mesodermal cell fate commitment	biological_process	The process in which a cell becomes committed to become a paraxial mesoderm cell.
GO:0048344	paraxial mesodermal cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048345	regulation of paraxial mesodermal cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.
GO:0048346	positive regulation of paraxial mesodermal cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.
GO:0048347	negative regulation of paraxial mesodermal cell fate determination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.
GO:0048348	paraxial mesodermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0048349	regulation of paraxial mesodermal cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.
GO:0048350	positive regulation of paraxial mesodermal cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.
GO:0048351	negative regulation of paraxial mesodermal cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.
GO:0048352	paraxial mesoderm structural organization	biological_process	The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
GO:0048353	primary endosperm nucleus	cellular_component	Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.
GO:0048354	mucilage biosynthetic process involved in seed coat development	biological_process	The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
GO:0048355	root cap mucilage biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.
GO:0048356	root epithelial mucilage biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.
GO:0048357	pedicel mucilage biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.
GO:0048358	mucilage pectin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.
GO:0048359	mucilage metabolic process involved in seed coat development	biological_process	The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
GO:0048360	root cap mucilage metabolic process	biological_process	The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth.
GO:0048361	root epithelial mucilage metabolic process	biological_process	The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.
GO:0048362	pedicel mucilage metabolic process	biological_process	The chemical reactions and pathways involving mucilage that occur in the flower stem.
GO:0048363	mucilage pectin metabolic process	biological_process	The chemical reactions and pathways involving the pectin component of mucilage.
GO:0048364	root development	biological_process	The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
GO:0048366	leaf development	biological_process	The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
GO:0048367	shoot system development	biological_process	The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.
GO:0048368	lateral mesoderm development	biological_process	The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.
GO:0048369	lateral mesoderm morphogenesis	biological_process	The process in which the anatomical structures of the lateral mesoderm are generated and organized.
GO:0048370	lateral mesoderm formation	biological_process	The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
GO:0048371	lateral mesodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.
GO:0048372	lateral mesodermal cell fate commitment	biological_process	The process in which a cell becomes committed to become a lateral mesoderm cell.
GO:0048373	lateral mesodermal cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048374	regulation of lateral mesodermal cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.
GO:0048375	negative regulation of lateral mesodermal cell fate determination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.
GO:0048376	positive regulation of lateral mesodermal cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.
GO:0048377	lateral mesodermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0048378	regulation of lateral mesodermal cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.
GO:0048379	positive regulation of lateral mesodermal cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.
GO:0048380	negative regulation of lateral mesodermal cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.
GO:0048381	lateral mesoderm structural organization	biological_process	The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.
GO:0048382	mesendoderm development	biological_process	The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
GO:0048383	mesectoderm development	biological_process	The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.
GO:0048384	retinoic acid receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
GO:0048385	regulation of retinoic acid receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
GO:0048388	endosomal lumen acidification	biological_process	Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.
GO:0048389	intermediate mesoderm development	biological_process	The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.
GO:0048390	intermediate mesoderm morphogenesis	biological_process	The process in which the anatomical structures of the intermediate mesoderm are generated and organized.
GO:0048391	intermediate mesoderm formation	biological_process	The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
GO:0048392	intermediate mesodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.
GO:0048393	intermediate mesodermal cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.
GO:0048394	intermediate mesodermal cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048395	regulation of intermediate mesodermal cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.
GO:0048396	negative regulation of intermediate mesodermal cell fate determination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.
GO:0048397	positive regulation of intermediate mesodermal cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.
GO:0048398	intermediate mesodermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0048399	regulation of intermediate mesodermal cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.
GO:0048400	positive regulation of intermediate mesodermal cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.
GO:0048401	negative regulation of intermediate mesodermal cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.
GO:0048402	intermediate mesoderm structural organization	biological_process	The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.
GO:0048403	brain-derived neurotrophic factor binding	molecular_function	Binding to brain-derived neurotrophic factor.
GO:0048406	nerve growth factor binding	molecular_function	Binding to nerve growth factor (NGF).
GO:0048407	platelet-derived growth factor binding	molecular_function	Binding to platelet-derived growth factor.
GO:0048408	epidermal growth factor binding	molecular_function	Binding to epidermal growth factor.
GO:0048437	floral organ development	biological_process	The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.
GO:0048438	floral whorl development	biological_process	The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.
GO:0048439	flower morphogenesis	biological_process	The process in which the anatomical structures of the flower are generated and organized.
GO:0048440	carpel development	biological_process	The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.
GO:0048441	petal development	biological_process	The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
GO:0048442	sepal development	biological_process	The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.
GO:0048443	stamen development	biological_process	The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.
GO:0048444	floral organ morphogenesis	biological_process	The process in which the anatomical structures of the floral organ are generated and organized.
GO:0048445	carpel morphogenesis	biological_process	The process in which the anatomical structures of the carpel are generated and organized.
GO:0048446	petal morphogenesis	biological_process	The process in which the anatomical structures of the petal are generated and organized.
GO:0048447	sepal morphogenesis	biological_process	The process in which the anatomical structures of the sepal are generated and organized.
GO:0048448	stamen morphogenesis	biological_process	The process in which the anatomical structures of the stamen are generated and organized.
GO:0048449	floral organ formation	biological_process	The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048450	floral organ structural organization	biological_process	The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.
GO:0048451	petal formation	biological_process	The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048452	petal structural organization	biological_process	The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.
GO:0048453	sepal formation	biological_process	The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048454	sepal structural organization	biological_process	The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.
GO:0048455	stamen formation	biological_process	The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048456	stamen structural organization	biological_process	The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.
GO:0048457	floral whorl morphogenesis	biological_process	The process in which the anatomical structures of the floral whorl are generated and organized.
GO:0048458	floral whorl formation	biological_process	The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048459	floral whorl structural organization	biological_process	The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.
GO:0048460	flower formation	biological_process	The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048461	flower structural organization	biological_process	The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.
GO:0048462	carpel formation	biological_process	The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.
GO:0048463	carpel structural organization	biological_process	The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.
GO:0048464	flower calyx development	biological_process	The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.
GO:0048465	corolla development	biological_process	The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.
GO:0048466	androecium development	biological_process	The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.
GO:0048467	gynoecium development	biological_process	The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.
GO:0048468	cell development	biological_process	The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.
GO:0048469	cell maturation	biological_process	The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state.
GO:0048471	perinuclear region of cytoplasm	cellular_component	Cytoplasm situated near, or occurring around, the nucleus.
GO:0048472	threonine-phosphate decarboxylase activity	molecular_function	Catalysis of the reaction: O-phospho-L-threonine + H+ = (R)-1-aminopropan-2-yl phosphate + CO2.
GO:0048473	D-methionine transport	biological_process	The directed movement of D-methionine into, out of, within, or between cells.
GO:0048475	coated membrane	cellular_component	A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.
GO:0048476	Holliday junction resolvase complex	cellular_component	An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.
GO:0048477	oogenesis	biological_process	The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
GO:0048479	style development	biological_process	The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.
GO:0048480	stigma development	biological_process	The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.
GO:0048481	plant ovule development	biological_process	The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
GO:0048482	plant ovule morphogenesis	biological_process	The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
GO:0048483	autonomic nervous system development	biological_process	The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.
GO:0048484	enteric nervous system development	biological_process	The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
GO:0048485	sympathetic nervous system development	biological_process	The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
GO:0048486	parasympathetic nervous system development	biological_process	The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
GO:0048487	beta-tubulin binding	molecular_function	Binding to the microtubule constituent protein beta-tubulin.
GO:0048488	synaptic vesicle endocytosis	biological_process	A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
GO:0048489	synaptic vesicle transport	biological_process	The directed movement of synaptic vesicles.
GO:0048490	anterograde synaptic vesicle transport	biological_process	The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
GO:0048491	retrograde synaptic vesicle transport	biological_process	The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body.
GO:0048492	ribulose bisphosphate carboxylase complex	cellular_component	A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
GO:0048493	plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex	cellular_component	A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
GO:0048494	chromatophore ribulose bisphosphate carboxylase complex	cellular_component	A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
GO:0048495	Roundabout binding	molecular_function	Binding to Roundabout (ROBO) receptor, a transmembrane receptor.
GO:0048496	maintenance of animal organ identity	biological_process	The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0048497	maintenance of floral organ identity	biological_process	The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0048498	establishment of petal orientation	biological_process	The process that determines the orientation of petals with reference to the central axis.
GO:0048499	synaptic vesicle membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.
GO:0048500	signal recognition particle	cellular_component	A complex of protein and RNA which facilitates translocation of proteins across membranes.
GO:0048501	signal recognition particle, plasma membrane targeting	cellular_component	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.
GO:0048502	ABC-type thiamine transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H+ + phosphate + thiamine(in).
GO:0048504	regulation of timing of animal organ formation	biological_process	Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development.
GO:0048505	regulation of timing of cell differentiation	biological_process	The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.
GO:0048506	regulation of timing of meristematic phase transition	biological_process	Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.
GO:0048507	meristem development	biological_process	The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
GO:0048508	embryonic meristem development	biological_process	The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.
GO:0048509	regulation of meristem development	biological_process	Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
GO:0048510	regulation of timing of transition from vegetative to reproductive phase	biological_process	The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
GO:0048511	rhythmic process	biological_process	Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.
GO:0048512	circadian behavior	biological_process	The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
GO:0048513	animal organ development	biological_process	Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0048514	blood vessel morphogenesis	biological_process	The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
GO:0048515	spermatid differentiation	biological_process	The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048518	positive regulation of biological process	biological_process	Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519	negative regulation of biological process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048520	positive regulation of behavior	biological_process	Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GO:0048521	negative regulation of behavior	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GO:0048522	positive regulation of cellular process	biological_process	Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048523	negative regulation of cellular process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048524	positive regulation of viral process	biological_process	Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.
GO:0048525	negative regulation of viral process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
GO:0048526	imaginal disc-derived wing expansion	biological_process	The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
GO:0048527	lateral root development	biological_process	The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
GO:0048528	post-embryonic root development	biological_process	The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.
GO:0048529	magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity	molecular_function	Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.
GO:0048530	fruit morphogenesis	biological_process	The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.
GO:0048531	beta-1,3-galactosyltransferase activity	molecular_function	Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.
GO:0048532	anatomical structure arrangement	biological_process	The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048533	sporocyte differentiation	biological_process	The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
GO:0048534	hematopoietic or lymphoid organ development	biological_process	The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
GO:0048535	lymph node development	biological_process	The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
GO:0048536	spleen development	biological_process	The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
GO:0048537	mucosa-associated lymphoid tissue development	biological_process	The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.
GO:0048538	thymus development	biological_process	The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
GO:0048539	bone marrow development	biological_process	The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
GO:0048540	bursa of Fabricius development	biological_process	The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.
GO:0048541	Peyer's patch development	biological_process	The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.
GO:0048542	lymph gland development	biological_process	The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
GO:0048543	phytochrome chromophore biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.
GO:0048544	recognition of pollen	biological_process	A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma.
GO:0048545	response to steroid hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
GO:0048546	digestive tract morphogenesis	biological_process	The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.
GO:0048548	regulation of pinocytosis	biological_process	Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
GO:0048549	positive regulation of pinocytosis	biological_process	Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
GO:0048550	negative regulation of pinocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
GO:0048555	generative cell nucleus	cellular_component	The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.
GO:0048556	microsporocyte nucleus	cellular_component	The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.
GO:0048557	embryonic digestive tract morphogenesis	biological_process	The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
GO:0048559	establishment of floral organ orientation	biological_process	The process that determines the orientation of the floral organs with reference to the central axis of the flower.
GO:0048560	establishment of anatomical structure orientation	biological_process	The process that determines the orientation of an anatomical structure with reference to an axis.
GO:0048561	establishment of animal organ orientation	biological_process	The process that determines the orientation of an animal organ or tissue with reference to an axis.
GO:0048562	embryonic organ morphogenesis	biological_process	Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0048563	post-embryonic animal organ morphogenesis	biological_process	Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0048564	photosystem I assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.
GO:0048565	digestive tract development	biological_process	The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
GO:0048566	embryonic digestive tract development	biological_process	The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
GO:0048567	ectodermal digestive tract morphogenesis	biological_process	The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.
GO:0048568	embryonic organ development	biological_process	Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0048569	post-embryonic animal organ development	biological_process	Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0048570	notochord morphogenesis	biological_process	The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
GO:0048571	long-day photoperiodism	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length.
GO:0048572	short-day photoperiodism	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.
GO:0048573	photoperiodism, flowering	biological_process	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
GO:0048574	long-day photoperiodism, flowering	biological_process	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.
GO:0048575	short-day photoperiodism, flowering	biological_process	A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.
GO:0048576	positive regulation of short-day photoperiodism, flowering	biological_process	Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048577	negative regulation of short-day photoperiodism, flowering	biological_process	Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048578	positive regulation of long-day photoperiodism, flowering	biological_process	Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048579	negative regulation of long-day photoperiodism, flowering	biological_process	Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048580	regulation of post-embryonic development	biological_process	Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
GO:0048581	negative regulation of post-embryonic development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
GO:0048582	positive regulation of post-embryonic development	biological_process	Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
GO:0048583	regulation of response to stimulus	biological_process	Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0048584	positive regulation of response to stimulus	biological_process	Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0048585	negative regulation of response to stimulus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0048586	regulation of long-day photoperiodism, flowering	biological_process	Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048587	regulation of short-day photoperiodism, flowering	biological_process	Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
GO:0048588	developmental cell growth	biological_process	The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.
GO:0048589	developmental growth	biological_process	The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
GO:0048592	eye morphogenesis	biological_process	The process in which the anatomical structures of the eye are generated and organized.
GO:0048593	camera-type eye morphogenesis	biological_process	The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
GO:0048596	embryonic camera-type eye morphogenesis	biological_process	The process in which the anatomical structures of the eye are generated and organized during embryonic development.
GO:0048597	post-embryonic camera-type eye morphogenesis	biological_process	The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.
GO:0048598	embryonic morphogenesis	biological_process	The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
GO:0048599	oocyte development	biological_process	The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0048600	oocyte fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.
GO:0048601	oocyte morphogenesis	biological_process	The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.
GO:0048608	reproductive structure development	biological_process	The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.
GO:0048609	multicellular organismal reproductive process	biological_process	The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
GO:0048611	embryonic ectodermal digestive tract development	biological_process	The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.
GO:0048612	post-embryonic ectodermal digestive tract development	biological_process	The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.
GO:0048613	embryonic ectodermal digestive tract morphogenesis	biological_process	The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
GO:0048614	post-embryonic ectodermal digestive tract morphogenesis	biological_process	The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.
GO:0048615	embryonic anterior midgut (ectodermal) morphogenesis	biological_process	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.
GO:0048616	post-embryonic anterior midgut (ectodermal) morphogenesis	biological_process	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.
GO:0048617	embryonic foregut morphogenesis	biological_process	The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.
GO:0048618	post-embryonic foregut morphogenesis	biological_process	The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.
GO:0048619	embryonic hindgut morphogenesis	biological_process	The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.
GO:0048620	post-embryonic hindgut morphogenesis	biological_process	The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.
GO:0048621	post-embryonic digestive tract morphogenesis	biological_process	The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.
GO:0048623	seed germination on parent plant	biological_process	The process in which a seed germinates before being shed from the parent plant.
GO:0048624	plantlet formation on parent plant	biological_process	The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.
GO:0048625	myoblast fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0048626	myoblast fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0048627	myoblast development	biological_process	The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0048628	myoblast maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0048629	trichome patterning	biological_process	The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.
GO:0048630	skeletal muscle tissue growth	biological_process	The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.
GO:0048631	regulation of skeletal muscle tissue growth	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle growth.
GO:0048632	negative regulation of skeletal muscle tissue growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.
GO:0048633	positive regulation of skeletal muscle tissue growth	biological_process	Any process that activates, maintains or increases the rate of skeletal muscle growth.
GO:0048634	regulation of muscle organ development	biological_process	Any process that modulates the frequency, rate or extent of muscle development.
GO:0048635	negative regulation of muscle organ development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
GO:0048636	positive regulation of muscle organ development	biological_process	Any process that activates, maintains or increases the rate of muscle development.
GO:0048638	regulation of developmental growth	biological_process	Any process that modulates the frequency, rate or extent of developmental growth.
GO:0048639	positive regulation of developmental growth	biological_process	Any process that activates, maintains or increases the rate of developmental growth.
GO:0048640	negative regulation of developmental growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.
GO:0048641	regulation of skeletal muscle tissue development	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.
GO:0048642	negative regulation of skeletal muscle tissue development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.
GO:0048643	positive regulation of skeletal muscle tissue development	biological_process	Any process that activates, maintains or increases the rate of skeletal muscle tissue development.
GO:0048644	muscle organ morphogenesis	biological_process	The process in which the anatomical structures of muscle are generated and organized.
GO:0048645	animal organ formation	biological_process	The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.
GO:0048646	anatomical structure formation involved in morphogenesis	biological_process	The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048647	polyphenic determination	biological_process	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.
GO:0048648	caste determination	biological_process	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
GO:0048649	caste determination, influence by genetic factors	biological_process	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
GO:0048650	caste determination, influence by environmental factors	biological_process	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
GO:0048651	polyphenic determination, influence by environmental factors	biological_process	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.
GO:0048652	polyphenic determination, influence by genetic factors	biological_process	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.
GO:0048653	anther development	biological_process	The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.
GO:0048654	anther morphogenesis	biological_process	The process in which the anatomical structures of the anther are generated and organized.
GO:0048655	anther wall tapetum morphogenesis	biological_process	The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
GO:0048656	anther wall tapetum formation	biological_process	The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
GO:0048657	anther wall tapetum cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
GO:0048658	anther wall tapetum development	biological_process	The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.
GO:0048659	smooth muscle cell proliferation	biological_process	The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.
GO:0048660	regulation of smooth muscle cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
GO:0048661	positive regulation of smooth muscle cell proliferation	biological_process	Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
GO:0048662	negative regulation of smooth muscle cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
GO:0048663	neuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
GO:0048664	neuron fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048665	neuron fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0048666	neuron development	biological_process	The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048667	cell morphogenesis involved in neuron differentiation	biological_process	The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
GO:0048668	collateral sprouting	biological_process	The process in which outgrowths develop from the shafts of existing axons.
GO:0048669	collateral sprouting in absence of injury	biological_process	The process in which outgrowths develop from the axons of intact undamaged neurons.
GO:0048670	regulation of collateral sprouting	biological_process	Any process that modulates the frequency, rate or extent of collateral sprouting.
GO:0048671	negative regulation of collateral sprouting	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.
GO:0048672	positive regulation of collateral sprouting	biological_process	Any process that activates or increases the frequency, rate or extent of collateral sprouting.
GO:0048673	collateral sprouting of intact axon in response to injury	biological_process	The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.
GO:0048674	collateral sprouting of injured axon	biological_process	The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.
GO:0048675	axon extension	biological_process	Long distance growth of a single axon process involved in cellular development.
GO:0048677	axon extension involved in regeneration	biological_process	Long distance growth of a single axon process involved in regeneration of the neuron.
GO:0048678	response to axon injury	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
GO:0048679	regulation of axon regeneration	biological_process	Any process that modulates the frequency, rate or extent of axon regeneration.
GO:0048680	positive regulation of axon regeneration	biological_process	Any process that activates, maintains or increases the rate of axon regeneration.
GO:0048681	negative regulation of axon regeneration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
GO:0048682	sprouting of injured axon	biological_process	The process involved in sprouting of an injured axon.
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	biological_process	Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.
GO:0048684	positive regulation of collateral sprouting of intact axon in response to injury	biological_process	Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.
GO:0048686	regulation of sprouting of injured axon	biological_process	Any process that modulates the frequency, rate or extent of sprouting of an injured axon.
GO:0048687	positive regulation of sprouting of injured axon	biological_process	Any process that activates, maintains or increases the rate of sprouting of an injured axon.
GO:0048688	negative regulation of sprouting of injured axon	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.
GO:0048689	formation of growth cone in injured axon	biological_process	The formation of a growth cone in an injured axon.
GO:0048690	regulation of axon extension involved in regeneration	biological_process	Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.
GO:0048691	positive regulation of axon extension involved in regeneration	biological_process	Any process that activates, maintains or increases the rate of axon extension involved in regeneration.
GO:0048692	negative regulation of axon extension involved in regeneration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.
GO:0048693	regulation of collateral sprouting of injured axon	biological_process	Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.
GO:0048694	positive regulation of collateral sprouting of injured axon	biological_process	Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.
GO:0048695	negative regulation of collateral sprouting of injured axon	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.
GO:0048696	regulation of collateral sprouting in absence of injury	biological_process	Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.
GO:0048697	positive regulation of collateral sprouting in absence of injury	biological_process	Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.
GO:0048698	negative regulation of collateral sprouting in absence of injury	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.
GO:0048699	generation of neurons	biological_process	The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
GO:0048700	acquisition of desiccation tolerance in seed	biological_process	The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.
GO:0048701	embryonic cranial skeleton morphogenesis	biological_process	The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
GO:0048702	embryonic neurocranium morphogenesis	biological_process	The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
GO:0048703	embryonic viscerocranium morphogenesis	biological_process	The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
GO:0048704	embryonic skeletal system morphogenesis	biological_process	The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
GO:0048705	skeletal system morphogenesis	biological_process	The process in which the anatomical structures of the skeleton are generated and organized.
GO:0048706	embryonic skeletal system development	biological_process	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.
GO:0048707	instar larval or pupal morphogenesis	biological_process	The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.
GO:0048708	astrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
GO:0048709	oligodendrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
GO:0048710	regulation of astrocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of astrocyte differentiation.
GO:0048711	positive regulation of astrocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.
GO:0048712	negative regulation of astrocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.
GO:0048713	regulation of oligodendrocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.
GO:0048714	positive regulation of oligodendrocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
GO:0048715	negative regulation of oligodendrocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.
GO:0048716	labrum morphogenesis	biological_process	The process in which the anatomical structures of labrum are generated and organized.
GO:0048717	anterior cibarial plate morphogenesis	biological_process	The process in which the anatomical structures of the anterior cibarial plate are generated and organized.
GO:0048718	cibarial fish-trap bristle morphogenesis	biological_process	The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
GO:0048719	epistomal sclerite morphogenesis	biological_process	The process in which the anatomical structures of the epistomal sclerite are generated and organized.
GO:0048720	posterior cibarial plate morphogenesis	biological_process	The process in which the anatomical structures of the posterior cibarial plate are generated and organized.
GO:0048721	clypeus morphogenesis	biological_process	The process in which the anatomical structures of the clypeus are generated and organized.
GO:0048722	anterior cibarial plate development	biological_process	The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.
GO:0048723	clypeus development	biological_process	The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.
GO:0048724	epistomal sclerite development	biological_process	The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.
GO:0048725	cibarial fish-trap bristle development	biological_process	The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
GO:0048726	labrum development	biological_process	The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.
GO:0048727	posterior cibarial plate development	biological_process	The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.
GO:0048728	proboscis development	biological_process	The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.
GO:0048729	tissue morphogenesis	biological_process	The process in which the anatomical structures of a tissue are generated and organized.
GO:0048730	epidermis morphogenesis	biological_process	The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
GO:0048731	system development	biological_process	The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0048732	gland development	biological_process	The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.
GO:0048733	sebaceous gland development	biological_process	The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.
GO:0048734	proboscis morphogenesis	biological_process	The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.
GO:0048735	haltere morphogenesis	biological_process	The process in which the anatomical structures of a haltere are generated and organized.
GO:0048736	appendage development	biological_process	The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
GO:0048737	imaginal disc-derived appendage development	biological_process	The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.
GO:0048738	cardiac muscle tissue development	biological_process	The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
GO:0048741	skeletal muscle fiber development	biological_process	The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
GO:0048742	regulation of skeletal muscle fiber development	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
GO:0048743	positive regulation of skeletal muscle fiber development	biological_process	Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
GO:0048744	negative regulation of skeletal muscle fiber development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
GO:0048745	smooth muscle tissue development	biological_process	The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.
GO:0048749	compound eye development	biological_process	The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
GO:0048750	compound eye corneal lens morphogenesis	biological_process	The process in which the anatomical structures of the compound eye corneal lens are generated and organized.
GO:0048752	semicircular canal morphogenesis	biological_process	The process in which the anatomical structures of the semicircular canals are generated and organized.
GO:0048753	pigment granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.
GO:0048754	branching morphogenesis of an epithelial tube	biological_process	The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
GO:0048755	branching morphogenesis of a nerve	biological_process	The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).
GO:0048756	sieve cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.
GO:0048757	pigment granule maturation	biological_process	Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
GO:0048758	companion cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.
GO:0048759	xylem vessel member cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
GO:0048760	plant parenchymal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.
GO:0048761	collenchyma cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.
GO:0048762	mesenchymal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
GO:0048763	calcium-induced calcium release activity	molecular_function	Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration.
GO:0048764	trichoblast maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.
GO:0048765	root hair cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
GO:0048766	root hair initiation	biological_process	The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.
GO:0048767	root hair elongation	biological_process	The process in which the root hair grows longer.
GO:0048768	root hair cell tip growth	biological_process	Localized growth of a plant root hair tip by extension of the cell wall.
GO:0048769	sarcomerogenesis	biological_process	The process in which sarcomeres are added in series within a fiber.
GO:0048770	pigment granule	cellular_component	A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.
GO:0048771	tissue remodeling	biological_process	The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.
GO:0048772	leucophore differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.
GO:0048773	erythrophore differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.
GO:0048774	cyanophore differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.
GO:0048775	regulation of leucophore differentiation	biological_process	Any process that modulates the frequency, rate or extent of leucophore differentiation.
GO:0048776	negative regulation of leucophore differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.
GO:0048777	positive regulation of leucophore differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of leucophore differentiation.
GO:0048778	regulation of erythrophore differentiation	biological_process	Any process that modulates the frequency, rate or extent of erythrophore differentiation.
GO:0048779	negative regulation of erythrophore differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.
GO:0048780	positive regulation of erythrophore differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.
GO:0048781	regulation of cyanophore differentiation	biological_process	Any process that modulates the frequency, rate or extent of cyanophore differentiation.
GO:0048782	negative regulation of cyanophore differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.
GO:0048783	positive regulation of cyanophore differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.
GO:0048784	pigment biosynthetic process involved in pigment granule maturation	biological_process	The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
GO:0048785	hatching gland development	biological_process	The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.
GO:0048786	presynaptic active zone	cellular_component	A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
GO:0048787	presynaptic active zone membrane	cellular_component	The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.
GO:0048788	cytoskeleton of presynaptic active zone	cellular_component	The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.
GO:0048789	cytoskeletal matrix organization at active zone	biological_process	The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
GO:0048790	maintenance of presynaptic active zone structure	biological_process	A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.
GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	biological_process	The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.
GO:0048792	spontaneous exocytosis of neurotransmitter	biological_process	The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.
GO:0048793	pronephros development	biological_process	The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
GO:0048794	swim bladder development	biological_process	The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
GO:0048795	swim bladder morphogenesis	biological_process	The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
GO:0048796	swim bladder maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
GO:0048797	swim bladder formation	biological_process	The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
GO:0048798	swim bladder inflation	biological_process	The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
GO:0048799	animal organ maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.
GO:0048800	antennal morphogenesis	biological_process	The process in which the anatomical structures of the antenna are generated and organized.
GO:0048801	antennal joint morphogenesis	biological_process	The process in which the anatomical structures of the antennal joint are generated and organized.
GO:0048802	notum morphogenesis	biological_process	The process in which the anatomical structures of the dorsal part of the body are generated and organized.
GO:0048803	imaginal disc-derived male genitalia morphogenesis	biological_process	The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.
GO:0048804	imaginal disc-derived female genitalia morphogenesis	biological_process	The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.
GO:0048805	imaginal disc-derived genitalia morphogenesis	biological_process	The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.
GO:0048806	genitalia development	biological_process	The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.
GO:0048807	female genitalia morphogenesis	biological_process	The process in which the anatomical structures of female genitalia are generated and organized.
GO:0048808	male genitalia morphogenesis	biological_process	The process in which the anatomical structures of male genitalia are generated and organized.
GO:0048809	analia morphogenesis	biological_process	The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.
GO:0048810	female analia morphogenesis	biological_process	The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
GO:0048811	male analia morphogenesis	biological_process	The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.
GO:0048812	neuron projection morphogenesis	biological_process	The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
GO:0048813	dendrite morphogenesis	biological_process	The process in which the anatomical structures of a dendrite are generated and organized.
GO:0048814	regulation of dendrite morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
GO:0048816	ocellus morphogenesis	biological_process	The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.
GO:0048817	negative regulation of hair follicle maturation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.
GO:0048818	positive regulation of hair follicle maturation	biological_process	Any process that activates or increases the frequency, rate or extent of hair follicle maturation.
GO:0048819	regulation of hair follicle maturation	biological_process	Any process that modulates the frequency, rate or extent of hair follicle maturation.
GO:0048820	hair follicle maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.
GO:0048821	erythrocyte development	biological_process	The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
GO:0048822	enucleate erythrocyte development	biological_process	The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048823	nucleate erythrocyte development	biological_process	The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048824	pigment cell precursor differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.
GO:0048825	cotyledon development	biological_process	The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
GO:0048826	cotyledon morphogenesis	biological_process	The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
GO:0048827	phyllome development	biological_process	The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.
GO:0048829	root cap development	biological_process	The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
GO:0048830	adventitious root development	biological_process	The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
GO:0048831	regulation of shoot system development	biological_process	Any process that modulates the frequency, rate or extent of shoot development.
GO:0048832	specification of plant organ number	biological_process	The regionalization process that modulates the quantity of a particular type of plant organ.
GO:0048833	specification of floral organ number	biological_process	Any process that modulates the number of floral organs formed in a floral whorl.
GO:0048834	specification of petal number	biological_process	Any process that modulates the number of petals formed in a flower.
GO:0048835	specification of decreased petal number	biological_process	Any process that reduces the number of petals produced in a developing flower.
GO:0048836	specification of increased petal number	biological_process	Any process that increases the number of petals produced in a developing flower.
GO:0048837	sorocarp sorus development	biological_process	The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp.
GO:0048838	release of seed from dormancy	biological_process	The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.
GO:0048839	inner ear development	biological_process	The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
GO:0048840	otolith development	biological_process	The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.
GO:0048841	regulation of axon extension involved in axon guidance	biological_process	Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.
GO:0048842	positive regulation of axon extension involved in axon guidance	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.
GO:0048843	negative regulation of axon extension involved in axon guidance	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.
GO:0048844	artery morphogenesis	biological_process	The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.
GO:0048845	venous blood vessel morphogenesis	biological_process	The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.
GO:0048846	axon extension involved in axon guidance	biological_process	The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
GO:0048847	adenohypophysis formation	biological_process	The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
GO:0048848	neurohypophysis morphogenesis	biological_process	The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
GO:0048849	neurohypophysis formation	biological_process	The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
GO:0048850	hypophysis morphogenesis	biological_process	The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
GO:0048851	hypophysis formation	biological_process	The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.
GO:0048852	diencephalon morphogenesis	biological_process	The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
GO:0048853	forebrain morphogenesis	biological_process	The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
GO:0048854	brain morphogenesis	biological_process	The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
GO:0048855	adenohypophysis morphogenesis	biological_process	The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
GO:0048856	anatomical structure development	biological_process	The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048857	neural nucleus development	biological_process	The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.
GO:0048858	cell projection morphogenesis	biological_process	The process in which the anatomical structures of a cell projection are generated and organized.
GO:0048859	formation of anatomical boundary	biological_process	The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048860	glioblast division	biological_process	The process resulting in the physical partitioning and separation of a glioblast into daughter cells.
GO:0048861	leukemia inhibitory factor signaling pathway	biological_process	The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0048863	stem cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
GO:0048864	stem cell development	biological_process	The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.
GO:0048865	stem cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.
GO:0048866	stem cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0048867	stem cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.
GO:0048868	pollen tube development	biological_process	The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.
GO:0048869	cellular developmental process	biological_process	A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0048870	cell motility	biological_process	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GO:0048871	multicellular organismal-level homeostasis	biological_process	Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.
GO:0048872	homeostasis of number of cells	biological_process	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
GO:0048873	homeostasis of number of cells within a tissue	biological_process	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.
GO:0048874	host-mediated regulation of intestinal microbiota composition	biological_process	The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.
GO:0048877	homeostasis of number of retina cells	biological_process	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.
GO:0048878	chemical homeostasis	biological_process	Any biological process involved in the maintenance of an internal steady state of a chemical.
GO:0048880	sensory system development	biological_process	The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
GO:0048881	mechanosensory lateral line system development	biological_process	The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
GO:0048882	lateral line development	biological_process	The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.
GO:0048883	neuromast primordium migration	biological_process	The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.
GO:0048884	neuromast development	biological_process	The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.
GO:0048885	neuromast deposition	biological_process	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.
GO:0048886	neuromast hair cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
GO:0048887	cupula development	biological_process	The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
GO:0048888	neuromast mantle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
GO:0048889	neuromast support cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
GO:0048890	lateral line ganglion development	biological_process	The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.
GO:0048891	lateral line ganglion neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.
GO:0048892	lateral line nerve development	biological_process	The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
GO:0048893	afferent axon development in lateral line nerve	biological_process	The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.
GO:0048894	efferent axon development in a lateral line nerve	biological_process	The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.
GO:0048895	lateral line nerve glial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.
GO:0048896	lateral line nerve glial cell migration	biological_process	The movement of a glial cell along the axons in a lateral line nerve.
GO:0048897	myelination of lateral line nerve axons	biological_process	The formation of compact myelin sheaths around the axons of a lateral line nerve.
GO:0048898	anterior lateral line system development	biological_process	The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
GO:0048899	anterior lateral line development	biological_process	The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
GO:0048900	anterior lateral line neuromast primordium migration	biological_process	The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
GO:0048901	anterior lateral line neuromast development	biological_process	The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
GO:0048902	anterior lateral line neuromast deposition	biological_process	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.
GO:0048903	anterior lateral line neuromast hair cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
GO:0048904	anterior lateral line neuromast cupula development	biological_process	The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
GO:0048905	anterior lateral line neuromast mantle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
GO:0048906	anterior lateral line neuromast support cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
GO:0048907	anterior lateral line ganglion development	biological_process	The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.
GO:0048908	anterior lateral line ganglion neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
GO:0048909	anterior lateral line nerve development	biological_process	The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
GO:0048910	afferent axon development in anterior lateral line nerve	biological_process	The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.
GO:0048911	efferent axon development in anterior lateral line nerve	biological_process	The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.
GO:0048912	glial cell migration in anterior lateral line nerve	biological_process	The movement of a glial cell along the axons in the anterior lateral line nerve.
GO:0048913	anterior lateral line nerve glial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
GO:0048914	myelination of anterior lateral line nerve axons	biological_process	The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.
GO:0048915	posterior lateral line system development	biological_process	The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
GO:0048916	posterior lateral line development	biological_process	The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
GO:0048917	posterior lateral line ganglion development	biological_process	The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.
GO:0048918	posterior lateral line nerve development	biological_process	The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
GO:0048919	posterior lateral line neuromast development	biological_process	The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
GO:0048920	posterior lateral line neuromast primordium migration	biological_process	The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
GO:0048921	posterior lateral line neuromast cupula development	biological_process	The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
GO:0048922	posterior lateral line neuromast deposition	biological_process	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.
GO:0048923	posterior lateral line neuromast hair cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
GO:0048924	posterior lateral line neuromast mantle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
GO:0048925	lateral line system development	biological_process	The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.
GO:0048926	electrosensory lateral line system development	biological_process	The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.
GO:0048927	posterior lateral line neuromast support cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
GO:0048928	posterior lateral line ganglion neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
GO:0048929	efferent axon development in posterior lateral line nerve	biological_process	The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.
GO:0048930	glial cell migration in posterior lateral line nerve	biological_process	The movement of a glial cell along the axons in the posterior lateral line nerve.
GO:0048931	posterior lateral line nerve glial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
GO:0048932	myelination of posterior lateral line nerve axons	biological_process	The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.
GO:0048933	afferent axon development in posterior lateral line nerve	biological_process	The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.
GO:0048934	peripheral nervous system neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.
GO:0048935	peripheral nervous system neuron development	biological_process	The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
GO:0048936	peripheral nervous system neuron axonogenesis	biological_process	Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
GO:0048937	lateral line nerve glial cell development	biological_process	The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048938	lateral line nerve glial cell morphogenesis involved in differentiation	biological_process	The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.
GO:0048939	anterior lateral line nerve glial cell development	biological_process	The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048940	anterior lateral line nerve glial cell morphogenesis involved in differentiation	biological_process	The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.
GO:0048941	posterior lateral line nerve glial cell development	biological_process	The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0048942	posterior lateral line nerve glial cell morphogenesis involved in differentiation	biological_process	The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.
GO:0050000	chromosome localization	biological_process	Any process in which a chromosome is transported to, or maintained in, a specific location.
GO:0050001	D-glutaminase activity	molecular_function	Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate.
GO:0050002	D-proline reductase (dithiol) activity	molecular_function	Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline.
GO:0050003	deoxycytidylate C-methyltransferase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.
GO:0050004	isoflavone 7-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.
GO:0050005	isohexenylglutaconyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O.
GO:0050006	isomaltulose synthase activity	molecular_function	Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.
GO:0050007	isonocardicin synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H+ + isonocardicin A.
GO:0050008	isopiperitenone delta-isomerase activity	molecular_function	Catalysis of the reaction: isopiperitenone = piperitenone.
GO:0050009	isopropanol dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + propan-2-ol = acetone + H+ + NADPH.
GO:0050010	isovitexin beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.
GO:0050011	itaconyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.
GO:0050012	juglone 3-hydroxylase activity	molecular_function	Catalysis of the reaction: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H+.
GO:0050013	2-dehydropantoate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.
GO:0050014	ketotetrose-phosphate aldolase activity	molecular_function	Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.
GO:0050015	kievitone hydratase activity	molecular_function	Catalysis of the reaction: kievitone hydrate = H2O + H+ + kievitone.
GO:0050016	kynurenine 7,8-hydroxylase activity	molecular_function	Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.
GO:0050017	L-3-cyanoalanine synthase activity	molecular_function	Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.
GO:0050018	L-amino-acid dehydrogenase activity	molecular_function	Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.
GO:0050019	L-arabinitol 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-arabinitol + NAD+ = L-xylulose + H+ + NADH.
GO:0050020	L-arabinonate dehydratase activity	molecular_function	Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O.
GO:0050021	L-arabinonolactonase activity	molecular_function	Catalysis of the reaction: L-arabinono-1,4-lactone + H2O = L-arabinonate + H+.
GO:0050022	L-arabinose 1-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.
GO:0050023	L-fuconate dehydratase activity	molecular_function	Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O.
GO:0050024	L-galactonolactone oxidase activity	molecular_function	Catalysis of the reaction: L-galactono-1,4-lactone + O2 = L-ascorbate + H2O2 + H+.
GO:0050025	L-glutamate oxidase activity	molecular_function	Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.
GO:0050026	L-glycol dehydrogenase activity	molecular_function	Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.
GO:0050028	L-lysine-lactamase activity	molecular_function	Catalysis of the reaction: L-2-aminohexano-6-lactam + H2O = L-lysine.
GO:0050029	L-lysine oxidase activity	molecular_function	Catalysis of the reaction: L-lysine + H2O + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4.
GO:0050030	L-pipecolate dehydrogenase activity	molecular_function	Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
GO:0050031	L-pipecolate oxidase activity	molecular_function	Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
GO:0050032	L-rhamnonate dehydratase activity	molecular_function	Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O.
GO:0050033	L-rhamnono-1,4-lactonase activity	molecular_function	Catalysis of the reaction: L-rhamnono-1,4-lactone + H2O = L-rhamnonate + H+.
GO:0050034	L-rhamnose 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-rhamnofuranose + NAD+ = L-rhamnono-1,4-lactone + H+ + NADH.
GO:0050035	L-sorbose oxidase activity	molecular_function	Catalysis of the reaction: L-sorbose + O2 = 5-dehydro-D-fructose + H2O2.
GO:0050036	L-threonate 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-threonate + NAD+ = 3-dehydro-L-threonate + H+ + NADH.
GO:0050037	L-xylose 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: aldehydo-L-xylose + NADP+ = L-xylono-1,4-lactone + H+ + NADPH.
GO:0050038	L-xylulose reductase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + xylitol = L-xylulose + H+ + NADPH.
GO:0050039	lactaldehyde reductase (NADPH) activity	molecular_function	Catalysis of the reaction: NADP+ + propane-1,2-diol = (S)-lactaldehyde + H+ + NADPH.
GO:0050040	lactate 2-monooxygenase activity	molecular_function	Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O.
GO:0050041	lactate aldolase activity	molecular_function	Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.
GO:0050042	lactate-malate transhydrogenase activity	molecular_function	Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.
GO:0050043	lactate racemase activity	molecular_function	Catalysis of the reaction: (S)-lactate = (R)-lactate.
GO:0050044	galactose-6-phosphate isomerase activity	molecular_function	Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.
GO:0050045	laminaribiose phosphorylase activity	molecular_function	Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.
GO:0050046	delta7-sterol 5(6)-desaturase activity	molecular_function	Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O.
GO:0050047	leucine 2,3-aminomutase activity	molecular_function	Catalysis of the reaction: L-leucine = (3R)-beta-leucine.
GO:0050048	L-leucine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
GO:0050049	leucine dehydrogenase activity	molecular_function	Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH.
GO:0050050	leucine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H+.
GO:0050051	leukotriene-B4 20-monooxygenase activity	molecular_function	Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
GO:0050052	leukotriene-E4 20-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + leukotriene E(4) + NADPH + O2 = 20-hydroxy-leukotriene E(4) + H2O + NADP+.
GO:0050053	levansucrase activity	molecular_function	Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).
GO:0050054	lignostilbene alpha beta-dioxygenase activity	molecular_function	Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.
GO:0050055	limonin-D-ring-lactonase activity	molecular_function	Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.
GO:0050056	linalool 8-monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + linalool + O2 = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H2O.
GO:0050057	linamarin synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.
GO:0050058	linoleate isomerase activity	molecular_function	Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.
GO:0050059	lombricine kinase activity	molecular_function	Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.
GO:0050060	long-chain-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.
GO:0050061	long-chain-aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
GO:0050062	long-chain-fatty-acyl-CoA reductase activity	molecular_function	Catalysis of the reaction: a long-chain fatty aldehyde + CoA + NADP+ = a long-chain fatty acyl-CoA + NADPH.
GO:0050064	luteolin 7-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.
GO:0050065	lysine-pyruvate 6-transaminase activity	molecular_function	Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine.
GO:0050066	lysine 2,3-aminomutase activity	molecular_function	Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.
GO:0050067	lysine 2-monooxygenase activity	molecular_function	Catalysis of the reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O.
GO:0050068	lysine carbamoyltransferase activity	molecular_function	Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H+ + phosphate.
GO:0050069	lysine dehydrogenase activity	molecular_function	Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH.
GO:0050070	lysolecithin acylmutase activity	molecular_function	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.
GO:0050071	phosphatidylglycerol lysyltransferase activity	molecular_function	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-lysyl-tRNA(Lys) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys).
GO:0050073	macrolide 2'-kinase activity	molecular_function	Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H+ + oleandomycin 2'-O-phosphate.
GO:0050074	malate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.
GO:0050075	maleate hydratase activity	molecular_function	Catalysis of the reaction: (R)-malate = H2O + maleate.
GO:0050076	maleate isomerase activity	molecular_function	Catalysis of the reaction: maleate = fumarate.
GO:0050077	maleylpyruvate isomerase activity	molecular_function	Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.
GO:0050078	malonate CoA-transferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.
GO:0050079	acetylenecarboxylate hydratase activity, producing 3-oxopropanoate	molecular_function	Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.
GO:0050080	malonyl-CoA decarboxylase activity	molecular_function	Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.
GO:0050081	maltose-6'-phosphate glucosidase activity	molecular_function	Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.
GO:0050082	maltose phosphorylase activity	molecular_function	Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
GO:0050083	malyl-CoA lyase activity	molecular_function	Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.
GO:0050084	mannitol-1-phosphatase activity	molecular_function	Catalysis of the reaction: D-mannitol 1-phosphate + H2O = D-mannitol + 2 H+ + phosphate.
GO:0050085	mannitol 2-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-mannitol + NADP+ = D-fructose + H+ + NADPH.
GO:0050086	mannitol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.
GO:0050087	mannitol dehydrogenase (cytochrome) activity	molecular_function	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + D-mannitol = 2 [Fe(II)cytochrome c] + D-fructose + 2 H+.
GO:0050088	mannose-6-phosphate 6-reductase activity	molecular_function	Catalysis of the reaction: D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + 3 H+ + NADPH.
GO:0050089	mannose isomerase activity	molecular_function	Catalysis of the reaction: D-mannose = D-fructose.
GO:0050090	mannuronate reductase activity	molecular_function	Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.
GO:0050091	melilotate 3-monooxygenase activity	molecular_function	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H+ + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+.
GO:0050092	meso-tartrate dehydrogenase activity	molecular_function	Catalysis of the reaction: (2R,3S)-tartrate + NAD+ = dihydroxyfumarate + H+ + NADH.
GO:0050093	methanol dehydrogenase activity	molecular_function	Catalysis of the reaction: methanol + NAD+ = formaldehyde + H+ + NADH.
GO:0050094	methionine-glyoxylate transaminase activity	molecular_function	Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.
GO:0050095	methionine decarboxylase activity	molecular_function	Catalysis of the reaction: L-methionine + H+ = 3-methylthiopropanamine + CO2.
GO:0050096	methylaspartate ammonia-lyase activity	molecular_function	Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH4.
GO:0050097	methylaspartate mutase activity	molecular_function	Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.
GO:0050098	methylguanidinase activity	molecular_function	Catalysis of the reaction: H2O + methylguanidine = methylammonium + urea.
GO:0050099	methylglutamate dehydrogenase activity	molecular_function	Catalysis of the reaction: N-methyl-L-glutamate + A + H2O = L-glutamate + AH(2) + formaldehyde.
GO:0050100	methylitaconate delta-isomerase activity	molecular_function	Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.
GO:0050101	mimosinase activity	molecular_function	Catalysis of the reaction: L-mimosine + H2O = 3-hydroxy-4H-pyrid-4-one + L-serine.
GO:0050102	cellodextrin phosphorylase activity	molecular_function	Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.
GO:0050103	dextrin dextranase activity	molecular_function	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).
GO:0050104	L-gulonate 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-gulonate + NAD+ = 3-dehydro-L-gulonate + H+ + NADH.
GO:0050105	L-gulonolactone oxidase activity	molecular_function	Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.
GO:0050106	monomethyl-sulfatase activity	molecular_function	Catalysis of the reaction: H2O + monomethyl sulfate = H+ + methanol + sulfate.
GO:0050107	monoterpenol O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.
GO:0050108	monoterpenyl-diphosphatase activity	molecular_function	Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.
GO:0050109	morphine 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.
GO:0050110	mucinaminylserine mucinaminidase activity	molecular_function	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.
GO:0050111	mycocerosate synthase activity	molecular_function	Catalysis of the reaction: acyl-CoA + 7n H+ + n methylmalonyl-CoA + 2n NADPH = n CO2 + n CoA + n H2O + multi-methyl-branched acyl-CoA + 2n NADP+.
GO:0050112	inositol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + H+ + NADH.
GO:0050113	inositol oxygenase activity	molecular_function	Catalysis of the reaction: myo-inositol + O2 = D-glucuronate + H2O + H+.
GO:0050114	myo-inosose-2 dehydratase activity	molecular_function	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O.
GO:0050115	myosin-light-chain-phosphatase activity	molecular_function	Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.
GO:0050116	N,N-dimethylformamidase activity	molecular_function	Catalysis of the reaction: N,N-dimethylformamide + H2O = dimethylamine + formate.
GO:0050117	N-acetyl-beta-alanine deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-beta-alanine + H2O = beta-alanine + acetate.
GO:0050118	N-acetyldiaminopimelate deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + acetate.
GO:0050119	N-acetylglucosamine deacetylase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosamine + H2O = D-glucosamine + acetate.
GO:0050120	N-acetylhexosamine 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + NAD+ = N-acetyl-D-glucosaminate + 2 H+ + NADH.
GO:0050121	N-acylglucosamine 2-epimerase activity	molecular_function	Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.
GO:0050122	N-acylhexosamine oxidase activity	molecular_function	Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + O2 = N-acetyl-D-glucosaminate + H2O2 + H+.
GO:0050123	N-acylmannosamine 1-dehydrogenase activity	molecular_function	Catalysis of the reaction: N-acyl-D-mannosamine + NAD+ = N-acyl-D-mannosaminolactone + H+ + NADH.
GO:0050124	N-acylneuraminate-9-phosphatase activity	molecular_function	Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.
GO:0050125	N-benzyloxycarbonylglycine hydrolase activity	molecular_function	Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O + H+ = benzyl alcohol + CO2 + glycine.
GO:0050126	N-carbamoylputrescine amidase activity	molecular_function	Catalysis of the reaction: N-carbamoylputrescine + H2O + 2 H+ = CO2 + NH4 + putrescine.
GO:0050127	N-carbamoylsarcosine amidase activity	molecular_function	Catalysis of the reaction: N-carbamoylsarcosine + H2O + 2 H+ = CO2 + NH4 + sarcosine.
GO:0050128	N-feruloylglycine deacylase activity	molecular_function	Catalysis of the reaction: N-feruloylglycine + H2O = ferulate + glycine.
GO:0050129	N-formylglutamate deformylase activity	molecular_function	Catalysis of the reaction: N-formyl-L-glutamate + H2O = L-glutamate + formate.
GO:0050130	N-methyl-2-oxoglutaramate hydrolase activity	molecular_function	Catalysis of the reaction: N-methyl-2-oxoglutaramate + H2O = 2-oxoglutarate + methylammonium.
GO:0050131	N-methyl-L-amino-acid oxidase activity	molecular_function	Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.
GO:0050132	N-methylalanine dehydrogenase activity	molecular_function	Catalysis of the reaction: N-methyl-L-alanine + H2O + NADP+ = H+ + methylammonium + NADPH + pyruvate.
GO:0050133	N6-hydroxylysine O-acetyltransferase activity	molecular_function	Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.
GO:0050134	N6-methyl-lysine oxidase activity	molecular_function	Catalysis of the reaction: N(6)-methyl-L-lysine + H2O + O2 = L-lysine + formaldehyde + H2O2.
GO:0050135	NAD(P)+ nucleosidase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide.
GO:0050136	NADH dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
GO:0050137	NADPH peroxidase activity	molecular_function	Catalysis of the reaction: H2O2 + H+ + NADPH = 2 H2O + NADP+.
GO:0050138	nicotinate dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NADP+ + nicotinate = 6-hydroxynicotinate + H+ + NADPH.
GO:0050139	nicotinate-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.
GO:0050140	nitrate reductase (cytochrome) activity	molecular_function	Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.
GO:0050141	nitroethane oxidase activity	molecular_function	Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2.
GO:0050142	nitrogenase (flavodoxin) activity	molecular_function	Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.
GO:0050143	nocardicin-A epimerase activity	molecular_function	Catalysis of the reaction: isonocardicin A = nocardicin A.
GO:0050144	nucleoside deoxyribosyltransferase activity	molecular_function	Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.
GO:0050145	nucleoside monophosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.
GO:0050146	nucleoside phosphotransferase activity	molecular_function	Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.
GO:0050147	nucleoside ribosyltransferase activity	molecular_function	Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.
GO:0050148	nucleotide diphosphokinase activity	molecular_function	Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.
GO:0050149	o-aminophenol oxidase activity	molecular_function	Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.
GO:0050150	o-pyrocatechuate decarboxylase activity	molecular_function	Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = catechol + CO2.
GO:0050151	oleate hydratase activity	molecular_function	Catalysis of the reaction: (R)-10-hydroxystearate = H2O + oleate.
GO:0050152	omega-amidase activity	molecular_function	Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.
GO:0050153	omega-hydroxydecanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: 10-hydroxydecanoate + NAD+ = 10-oxodecanoate + H+ + NADH.
GO:0050154	opheline kinase activity	molecular_function	Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H+.
GO:0050155	ornithine(lysine) transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate.
GO:0050156	ornithine N-benzoyltransferase activity	molecular_function	Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.
GO:0050157	ornithine racemase activity	molecular_function	Catalysis of the reaction: L-ornithine = D-ornithine.
GO:0050158	dihydroorotate dehydrogenase (NADPH) activity	molecular_function	Catalysis of the reaction: (S)-dihydroorotate + NADP+ = H+ + NADPH + orotate.
GO:0050159	orsellinate decarboxylase activity	molecular_function	Catalysis of the reaction: o-orsellinate + H+ = CO2 + orcinol.
GO:0050160	orsellinate-depside hydrolase activity	molecular_function	Catalysis of the reaction: H2O + orsellinate depside = 2 o-orsellinate + H+.
GO:0050161	succinyl-CoA:oxalate CoA-transferase	molecular_function	Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.
GO:0050162	oxalate oxidase activity	molecular_function	Catalysis of the reaction: 2 H+ + O2 + oxalate = 2 CO2 + H2O2.
GO:0050163	oxaloacetate tautomerase activity	molecular_function	Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.
GO:0050164	oxoglutarate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + CoA + NADP+ = CO2 + NADPH + succinyl-CoA.
GO:0050165	pantetheine kinase activity	molecular_function	Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.
GO:0050166	pantoate 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-pantoate + NAD+ = (R)-4-dehydropantoate + H+ + NADH.
GO:0050167	pantothenoylcysteine decarboxylase activity	molecular_function	Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H+ = (R)-pantetheine + CO2.
GO:0050168	pentanamidase activity	molecular_function	Catalysis of the reaction: H2O + pentanamide = NH4 + valerate.
GO:0050170	peptidyl-glutaminase activity	molecular_function	Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.
GO:0050171	phenol beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.
GO:0050172	phenylalanine 2-monooxygenase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O.
GO:0050174	phenylalanine decarboxylase activity	molecular_function	Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.
GO:0050175	phenylalanine dehydrogenase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH.
GO:0050176	phenylalanine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H+.
GO:0050177	phenylpyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.
GO:0050178	phenylpyruvate tautomerase activity	molecular_function	Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.
GO:0050179	phenylserine aldolase activity	molecular_function	Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.
GO:0050180	phloretin hydrolase activity	molecular_function	Catalysis of the reaction: H2O + phloretin = H+ + phloretate + phloroglucinol.
GO:0050181	phorbol-diester hydrolase activity	molecular_function	Catalysis of the reaction: H2O + phorbol 12,13-dibutanoate = butanoate + H+ + phorbol 13-butanoate.
GO:0050182	phosphate butyryltransferase activity	molecular_function	Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.
GO:0050183	phosphatidylcholine 12-monooxygenase activity	molecular_function	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H+ + NADH + O2 = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H2O + NAD+.
GO:0050184	phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: An oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a linoleoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.
GO:0050185	phosphatidylinositol deacylase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H2O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H+.
GO:0050186	phosphoadenylylsulfatase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.
GO:0050187	phosphoamidase activity	molecular_function	Catalysis of the reaction: N-phosphocreatine + H2O = creatine + phosphate.
GO:0050188	phosphoenolpyruvate mutase activity	molecular_function	Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.
GO:0050189	phosphoenolpyruvate phosphatase activity	molecular_function	Catalysis of the reaction: H2O + phosphoenolpyruvate = phosphate + pyruvate.
GO:0050190	phosphoglucokinase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H+.
GO:0050191	phosphoglycerate kinase (GTP) activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H+.
GO:0050192	phosphoglycerate phosphatase activity	molecular_function	Catalysis of the reaction: 2-phospho-D-glycerate + H2O = D-glycerate + phosphate.
GO:0050193	phosphoketolase activity	molecular_function	Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.
GO:0050194	phosphonoacetaldehyde hydrolase activity	molecular_function	Catalysis of the reaction: H2O + phosphonoacetaldehyde = acetaldehyde + H+ + phosphate.
GO:0050195	phosphoribokinase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H+.
GO:0050196	[phosphorylase] phosphatase activity	molecular_function	Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.
GO:0050197	phytanate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H+ + phytanoyl-CoA.
GO:0050198	pinosylvin synthase activity	molecular_function	Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H+ + 3 malonyl-CoA = 4 CO2 + 4 CoA + pinosylvin.
GO:0050199	piperidine N-piperoyltransferase activity	molecular_function	Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H+.
GO:0050200	plasmalogen synthase activity	molecular_function	Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.
GO:0050201	fucokinase activity	molecular_function	Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H+.
GO:0050202	octopamine dehydratase activity	molecular_function	Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH4.
GO:0050203	oxalate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H+ + oxalyl-CoA.
GO:0050204	oxalomalate lyase activity	molecular_function	Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.
GO:0050205	oxamate carbamoyltransferase activity	molecular_function	Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.
GO:0050206	oximinotransferase activity	molecular_function	Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.
GO:0050207	plasmanylethanolamine desaturase activity	molecular_function	Catalysis of the reaction:1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O.
GO:0050208	polysialic-acid O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.
GO:0050209	polyvinyl-alcohol oxidase activity	molecular_function	Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.
GO:0050210	prenyl-diphosphatase activity	molecular_function	Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.
GO:0050211	procollagen galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.
GO:0050212	progesterone 11-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + progesterone = 11alpha-hydroxyprogesterone + A + H2O.
GO:0050214	progesterone monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + progesterone = A + H2O + testosterone acetate.
GO:0050215	propanediol dehydratase activity	molecular_function	Catalysis of the reaction: propane-1,2-diol = H2O + propanal.
GO:0050216	propanediol-phosphate dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + propane-1,2-diol 1-phosphate = H+ + hydroxyacetone phosphate + NADH.
GO:0050217	propioin synthase activity	molecular_function	Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.
GO:0050218	propionate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.
GO:0050219	prostaglandin-A1 delta-isomerase activity	molecular_function	Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.
GO:0050220	prostaglandin-E synthase activity	molecular_function	Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).
GO:0050221	prostaglandin-E2 9-reductase activity	molecular_function	Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.
GO:0050223	protocatechuate decarboxylase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxybenzoate + H+ = catechol + CO2.
GO:0050224	prunasin beta-glucosidase activity	molecular_function	Catalysis of the reaction: (R)-prunasin + H2O = D-glucose + mandelonitrile.
GO:0050225	pseudouridine kinase activity	molecular_function	Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H+ + pseudouridine 5'-phosphate.
GO:0050226	psychosine sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.
GO:0050227	pteridine oxidase activity	molecular_function	Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.
GO:0050228	pterin deaminase activity	molecular_function	Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3.
GO:0050230	purine imidazole-ring cyclase activity	molecular_function	Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.
GO:0050231	putrescine carbamoyltransferase activity	molecular_function	Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H+ + phosphate.
GO:0050232	putrescine oxidase activity	molecular_function	Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.
GO:0050233	pyranose oxidase activity	molecular_function	Catalysis of the reaction: D-glucose + O2 = 2-dehydro-D-glucose + H2O2.
GO:0050234	pyrazolylalanine synthase activity	molecular_function	Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H2O.
GO:0050235	pyridoxal 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD+ + pyridoxal = 4-pyridoxolactone + H+ + NADH.
GO:0050236	pyridoxine:NADP 4-dehydrogenase activity	molecular_function	Catalysis of the reaction: NADP+ + pyridoxine = H+ + NADPH + pyridoxal.
GO:0050237	pyridoxine 4-oxidase activity	molecular_function	Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.
GO:0050238	pyridoxine 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.
GO:0050239	pyrithiamine deaminase activity	molecular_function	Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.
GO:0050240	pyrogallol 1,2-oxygenase activity	molecular_function	Catalysis of the reaction: O2 + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H+.
GO:0050241	pyrroline-2-carboxylate reductase activity	molecular_function	Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.
GO:0050242	pyruvate, phosphate dikinase activity	molecular_function	Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H+ + phosphoenolpyruvate.
GO:0050243	pyruvate dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: CoA + NADP+ + pyruvate = acetyl-CoA + CO2 + NADPH.
GO:0050244	pyruvate oxidase (CoA-acetylating) activity	molecular_function	Catalysis of the reaction: CoA + H+ + O2 + pyruvate = acetyl-CoA + CO2 + H2O2.
GO:0050245	quercitrinase activity	molecular_function	Catalysis of the reaction: H2O + quercitrin = L-rhamnose + quercetin.
GO:0050246	questin monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + questin = demethylsulochrin + NADP+.
GO:0050247	raucaffricine beta-glucosidase activity	molecular_function	Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine.
GO:0050248	Renilla-luciferin 2-monooxygenase activity	molecular_function	Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.
GO:0050249	Renilla-luciferin sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H+ + luciferyl sulfate.
GO:0050251	retinol isomerase activity	molecular_function	Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.
GO:0050252	retinol O-fatty-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.
GO:0050253	retinyl-palmitate esterase activity	molecular_function	Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.
GO:0050254	rhodopsin kinase activity	molecular_function	Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.
GO:0050255	ribitol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-ribitol + NAD+ = D-ribulose + H+ + NADH.
GO:0050256	ribitol-5-phosphate 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.
GO:0050257	riboflavin phosphotransferase activity	molecular_function	Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.
GO:0050258	riboflavinase activity	molecular_function	Catalysis of the reaction: H2O + H+ + riboflavin = D-ribitol + lumichrome.
GO:0050259	ribose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: H2O + NADP+ + ribofuranose = D-ribonate + 2 H+ + NADPH.
GO:0050260	ribose-5-phosphate-ammonia ligase activity	molecular_function	Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH4 = 5-phospho-D-ribosylamine + ADP + 2 H+ + phosphate.
GO:0050261	ribose isomerase activity	molecular_function	Catalysis of the reaction: ribofuranose = D-ribulose.
GO:0050262	ribosylnicotinamide kinase activity	molecular_function	Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H+ + nicotinamide mononucleotide.
GO:0050263	ribosylpyrimidine nucleosidase activity	molecular_function	Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.
GO:0050264	rifamycin-B oxidase activity	molecular_function	Catalysis of the reaction: 2 H+ + O2 + rifamycin B = H2O2 + rifamycin O.
GO:0050265	RNA uridylyltransferase activity	molecular_function	Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).
GO:0050266	rosmarinate synthase activity	molecular_function	Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.
GO:0050267	rubber cis-polyprenylcistransferase activity	molecular_function	Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.
GO:0050268	coniferyl-alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.
GO:0050269	coniferyl-aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.
GO:0050270	S-adenosylhomocysteine deaminase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O + H+ = S-inosyl-L-homocysteine + NH4.
GO:0050271	S-alkylcysteine lyase activity	molecular_function	Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.
GO:0050272	S-carboxymethylcysteine synthase activity	molecular_function	Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H+.
GO:0050273	S-succinylglutathione hydrolase activity	molecular_function	Catalysis of the reaction: S-succinylglutathione + H2O = glutathione + H+ + succinate.
GO:0050274	salicyl-alcohol beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H+ + salicin + UDP.
GO:0050275	scopoletin glucosyltransferase activity	molecular_function	Catalysis of the reaction: scopoletin + UDP-D-glucose = H+ + scopolin + UDP.
GO:0050276	scyllo-inosamine 4-kinase activity	molecular_function	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H+.
GO:0050277	sedoheptulokinase activity	molecular_function	Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H+ + sedoheptulose 7-phosphate.
GO:0050278	sedoheptulose-bisphosphatase activity	molecular_function	Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
GO:0050279	sepiapterin deaminase activity	molecular_function	Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.
GO:0050280	sequoyitol dehydrogenase activity	molecular_function	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADH.
GO:0050281	serine-glyoxylate transaminase activity	molecular_function	Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.
GO:0050282	serine 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.
GO:0050283	serine-sulfate ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate.
GO:0050284	sinapate 1-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.
GO:0050285	sinapine esterase activity	molecular_function	Catalysis of the reaction: O-sinapoylcholine + H2O = choline + H+ + sinapate.
GO:0050286	sorbitol-6-phosphatase activity	molecular_function	Catalysis of the reaction: D-glucitol 6-phosphate + H2O = D-glucitol + phosphate.
GO:0050287	sorbose 5-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: L-sorbose + NADP+ = 5-dehydro-D-fructose + H+ + NADPH.
GO:0050288	sorbose dehydrogenase activity	molecular_function	Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).
GO:0050289	spermidine dehydrogenase activity	molecular_function	Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.
GO:0050290	sphingomyelin phosphodiesterase D activity	molecular_function	Catalysis of the reaction: H2O + sphingomyelin = ceramide 1-phosphate + choline + H+.
GO:0050291	sphingosine N-acyltransferase activity	molecular_function	Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.
GO:0050292	steroid 9-alpha-monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O.
GO:0050293	steroid-lactonase activity	molecular_function	Catalysis of the reaction: H2O + testololactone = H+ + testolate.
GO:0050294	steroid sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.
GO:0050295	steryl-beta-glucosidase activity	molecular_function	Catalysis of the reaction: cholesteryl-beta-D-glucoside + H2O = D-glucose + cholesterol.
GO:0050296	stipitatonate decarboxylase activity	molecular_function	Catalysis of the reaction: H2O + stipitatonate = CO2 + H+ + stipitatate.
GO:0050297	stizolobate synthase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.
GO:0050298	stizolobinate synthase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.
GO:0050299	streptomycin 3''-kinase activity	molecular_function	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H+ + streptomycin 3''-phosphate.
GO:0050300	aminoglycoside 6-kinase activity	molecular_function	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H+ + streptomycin 6-phosphate.
GO:0050301	streptomycin-6-phosphatase activity	molecular_function	Catalysis of the reaction: H2O + streptomycin 6-phosphate = phosphate + streptomycin.
GO:0050302	indole-3-acetaldehyde oxidase activity	molecular_function	Catalysis of the reaction: (indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2 + H+.
GO:0050303	lysine 6-dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine.
GO:0050304	nitrous-oxide reductase activity	molecular_function	Catalysis of the reaction: H2O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.
GO:0050305	strombine dehydrogenase activity	molecular_function	Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H2O + NAD+ = glycine + H+ + NADH + pyruvate.
GO:0050306	sucrose 1F-fructosyltransferase activity	molecular_function	Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.
GO:0050307	sucrose-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.
GO:0050308	sugar-phosphatase activity	molecular_function	Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.
GO:0050309	sugar-terminal-phosphatase activity	molecular_function	Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.
GO:0050310	sulfite dehydrogenase activity	molecular_function	Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.
GO:0050311	sulfite reductase (ferredoxin) activity	molecular_function	Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.
GO:0050312	sulfoacetaldehyde lyase activity	molecular_function	Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.
GO:0050313	sulfur dioxygenase activity	molecular_function	Catalysis of the reaction: sulfur + O2 + H2O = sulfite.
GO:0050314	sym-norspermidine synthase activity	molecular_function	Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H+.
GO:0050315	synephrine dehydratase activity	molecular_function	Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.
GO:0050316	T2-induced deoxynucleotide kinase activity	molecular_function	Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP.
GO:0050317	tagatose kinase activity	molecular_function	Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H+.
GO:0050318	tannase activity	molecular_function	Catalysis of the reaction: digallate + H2O = 2 gallate + H+.
GO:0050319	tartrate decarboxylase activity	molecular_function	Catalysis of the reaction: L-tartrate + H+ = D-glycerate + CO2.
GO:0050320	tartrate epimerase activity	molecular_function	Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.
GO:0050321	tau-protein kinase activity	molecular_function	Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.
GO:0050322	taurine-2-oxoglutarate transaminase activity	molecular_function	Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.
GO:0050323	taurine dehydrogenase activity	molecular_function	Catalysis of the reaction: A + H2O + taurine = AH(2) + NH4 + sulfoacetaldehyde.
GO:0050324	taurocyamine kinase activity	molecular_function	Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H+.
GO:0050325	tauropine dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + tauropine = H+ + NADH + pyruvate + taurine.
GO:0050326	taxifolin 8-monooxygenase activity	molecular_function	Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.
GO:0050328	tetrahydroberberine oxidase activity	molecular_function	Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.
GO:0050329	tetrahydroxypteridine cycloisomerase activity	molecular_function	Catalysis of the reaction: tetrahydroxypteridine = H+ + xanthine-8-carboxylate.
GO:0050330	theanine hydrolase activity	molecular_function	Catalysis of the reaction: N(5)-ethyl-L-glutamine + H2O = L-glutamate + ethylamine.
GO:0050331	thiamine-diphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.
GO:0050332	thiamine pyridinylase activity	molecular_function	Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.
GO:0050333	thiamine triphosphate phosphatase activity	molecular_function	Catalysis of the reaction: H2O + thiamine triphosphate = thiamine diphosphate + H+ + phosphate.
GO:0050334	thiaminase activity	molecular_function	Catalysis of the reaction: H2O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H+.
GO:0050335	thiocyanate isomerase activity	molecular_function	Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.
GO:0050336	thioethanolamine S-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.
GO:0050337	thiosulfate-thiol sulfurtransferase activity	molecular_function	Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.
GO:0050338	thiosulfate dehydrogenase activity	molecular_function	Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.
GO:0050339	TTPase activity	molecular_function	Catalysis of the reaction: dTTP + H2O = dTDP + H+ + phosphate.
GO:0050340	thymidylate 5'-phosphatase activity	molecular_function	Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.
GO:0050341	thymine dioxygenase activity	molecular_function	Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.
GO:0050342	tocopherol O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.
GO:0050343	trans-2-enoyl-CoA reductase (NAD+) activity	molecular_function	Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.
GO:0050344	trans-cinnamate 2-monooxygenase activity	molecular_function	Catalysis of the reaction: trans-cinnamate + H+ + NADPH + O2 = 2-coumarate + H2O + NADP+.
GO:0050345	trans-epoxysuccinate hydrolase activity	molecular_function	Catalysis of the reaction: trans-2,3-epoxysuccinate + H2O = (2R,3S)-tartrate.
GO:0050346	trans-L-3-hydroxyproline dehydratase activity	molecular_function	Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H2O + H+.
GO:0050348	trehalose O-mycolyltransferase activity	molecular_function	Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.
GO:0050349	triacetate-lactonase activity	molecular_function	Catalysis of the reaction: H2O + triacetate lactone = triacetate.
GO:0050350	trihydroxystilbene synthase activity	molecular_function	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2.
GO:0050351	trimetaphosphatase activity	molecular_function	Catalysis of the reaction: H2O + trimetaphosphate = 2 H+ + triphosphate.
GO:0050352	trimethylamine-oxide aldolase activity	molecular_function	Catalysis of the reaction: H+ + trimethylamine N-oxide = dimethylamine + formaldehyde.
GO:0050353	trimethyllysine dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate.
GO:0050354	triokinase activity	molecular_function	Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H+.
GO:0050355	inorganic triphosphate phosphatase activity	molecular_function	Catalysis of the reaction: H2O + inorganic triphosphate = diphosphate + phosphate.
GO:0050356	tropine dehydrogenase activity	molecular_function	Catalysis of the reaction: NADP+ + tropine = H+ + NADPH + tropinone.
GO:0050357	tropinesterase activity	molecular_function	Catalysis of the reaction: atropine + H2O = H+ + tropate + tropine.
GO:0050358	tropinone reductase activity	molecular_function	Catalysis of the reaction: NADP+ + pseudotropine = H+ + NADPH + tropinone.
GO:0050359	tropomyosin kinase activity	molecular_function	Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.
GO:0050360	tryptophan 2'-dioxygenase activity	molecular_function	Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.
GO:0050361	tryptophan 2-monooxygenase activity	molecular_function	Catalysis of the reaction: L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide.
GO:0050362	L-tryptophan:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate.
GO:0050363	tryptophan dehydrogenase activity	molecular_function	Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+.
GO:0050364	tryptophan dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.
GO:0050365	tryptophanamidase activity	molecular_function	Catalysis of the reaction: L-tryptophanamide + H2O = L-tryptophan + NH4.
GO:0050366	tyramine N-feruloyltransferase activity	molecular_function	Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.
GO:0050367	tyrosine-arginine ligase activity	molecular_function	Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H+.
GO:0050368	tyrosine 2,3-aminomutase activity	molecular_function	Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.
GO:0050369	[tyrosine 3-monooxygenase] kinase activity	molecular_function	Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].
GO:0050370	tyrosine N-monooxygenase activity	molecular_function	Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.
GO:0050371	tyrosine phenol-lyase activity	molecular_function	Catalysis of the reaction: L-tyrosine + H2O = NH4 + phenol + pyruvate.
GO:0050373	UDP-arabinose 4-epimerase activity	molecular_function	Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.
GO:0050374	UDP-galacturonate decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + UDP-alpha-D-galacturonate = CO2 + UDP-L-arabinose.
GO:0050376	UDP-glucosamine 4-epimerase activity	molecular_function	Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.
GO:0050377	UDP-glucose 4,6-dehydratase activity	molecular_function	Catalysis of the reaction: UDP-D-glucose = H2O + UDP-4-dehydro-6-deoxy-D-glucose.
GO:0050378	UDP-glucuronate 4-epimerase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.
GO:0050379	UDP-glucuronate 5'-epimerase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.
GO:0050380	undecaprenyl-diphosphatase activity	molecular_function	Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.
GO:0050382	uracil-5-carboxylate decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + uracil 5-carboxylate = CO2 + uracil.
GO:0050383	uracil dehydrogenase activity	molecular_function	Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.
GO:0050384	urate-ribonucleotide phosphorylase activity	molecular_function	Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H+ + urate.
GO:0050385	ureidoglycolate lyase activity	molecular_function	Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.
GO:0050386	ureidosuccinase activity	molecular_function	Catalysis of the reaction: N-carbamoyl-L-aspartate + H2O + 2 H+ = L-aspartate + CO2 + NH4.
GO:0050387	urethanase activity	molecular_function	Catalysis of the reaction: H2O + H+ + urethane = CO2 + ethanol + NH4.
GO:0050388	uronate dehydrogenase activity	molecular_function	Catalysis of the reaction: D-galacturonate + H2O + NAD+ = galactarate + 2 H+ + NADH.
GO:0050389	uronolactonase activity	molecular_function	Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.
GO:0050390	valine decarboxylase activity	molecular_function	Catalysis of the reaction: L-valine + H+ = 2-methylpropanamine + CO2.
GO:0050391	valine dehydrogenase (NADP) activity	molecular_function	Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH.
GO:0050392	vicianin beta-glucosidase activity	molecular_function	Catalysis of the reaction: (R)-vicianin + H2O = mandelonitrile + vicianose.
GO:0050393	vinylacetyl-CoA delta-isomerase activity	molecular_function	Catalysis of the reaction: vinylacetyl-CoA = (2E)-butenoyl-CoA.
GO:0050394	viomycin kinase activity	molecular_function	Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.
GO:0050395	vitexin beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-glucose + vitexin = H+ + UDP + vitexin 2''-O-beta-D-glucoside.
GO:0050396	vomifoliol 4'-dehydrogenase activity	molecular_function	Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD+ = (6S)-6-hydroxy-3-oxo-alpha-ionone + H+ + NADH.
GO:0050397	Watasenia-luciferin 2-monooxygenase activity	molecular_function	Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.
GO:0050398	wax-ester hydrolase activity	molecular_function	Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.
GO:0050399	xanthommatin reductase activity	molecular_function	Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD+ = H+ + NADH + xanthommatin.
GO:0050400	xylitol kinase activity	molecular_function	Catalysis of the reaction: ATP + xylitol = ADP + 2 H+ + xylitol 5-phosphate.
GO:0050401	xylonate dehydratase activity	molecular_function	Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.
GO:0050402	xylono-1,4-lactonase activity	molecular_function	Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.
GO:0050403	trans-zeatin O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H+ + UDP.
GO:0050404	zeatin O-beta-D-xylosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H+ + UDP.
GO:0050405	[acetyl-CoA carboxylase] kinase activity	molecular_function	Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.
GO:0050406	[acetyl-CoA carboxylase]-phosphatase activity	molecular_function	Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.
GO:0050407	[glycogen-synthase-D] phosphatase activity	molecular_function	Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.
GO:0050408	[pyruvate kinase]-phosphatase activity	molecular_function	Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.
GO:0050409	indolylacetylinositol arabinosyltransferase activity	molecular_function	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H+ + UDP.
GO:0050410	3-oxolaurate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-oxolaurate + H+ = 2-undecanone + CO2.
GO:0050412	cinnamate beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.
GO:0050413	D-alanine 2-hydroxymethyltransferase activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.
GO:0050414	formimidoylaspartate deiminase activity	molecular_function	Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.
GO:0050415	formimidoylglutamase activity	molecular_function	Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide.
GO:0050416	formimidoylglutamate deiminase activity	molecular_function	Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3.
GO:0050417	glutamin-(asparagin-)ase activity	molecular_function	Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate.
GO:0050418	hydroxylamine reductase activity	molecular_function	Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.
GO:0050419	hydroxymandelonitrile lyase activity	molecular_function	Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.
GO:0050420	maltose synthase activity	molecular_function	Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.
GO:0050421	nitrite reductase (NO-forming) activity	molecular_function	Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.
GO:0050422	strictosidine beta-glucosidase activity	molecular_function	Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone.
GO:0050423	thiamine oxidase activity	molecular_function	Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	biological_process	The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
GO:0050429	calcium-dependent phospholipase C activity	molecular_function	Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.
GO:0050431	transforming growth factor beta binding	molecular_function	Binding to TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
GO:0050432	catecholamine secretion	biological_process	The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
GO:0050433	regulation of catecholamine secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.
GO:0050434	positive regulation of viral transcription	biological_process	Any process that activates or increases the frequency, rate or extent of viral transcription.
GO:0050435	amyloid-beta metabolic process	biological_process	The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).
GO:0050436	microfibril binding	molecular_function	Binding to a microfibril, any small fibril occurring in biological material.
GO:0050437	(-)-endo-fenchol synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate.
GO:0050438	2-ethylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H2O = (R)-2-ethylmalate + CoA + H+.
GO:0050439	2-hydroxy-3-oxoadipate synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H+ = 2-hydroxy-3-oxoadipate + CO2.
GO:0050440	2-methylcitrate synthase activity	molecular_function	Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+.
GO:0050441	3-ethylmalate synthase activity	molecular_function	Catalysis of the reaction: butanoyl-CoA + glyoxylate + H2O = 3-ethylmalate + CoA + H+.
GO:0050442	3-propylmalate synthase activity	molecular_function	Catalysis of the reaction: glyoxylate + H2O + pentanoyl-CoA = 3-propylmalate + CoA + H+.
GO:0050445	asparagusate reductase activity	molecular_function	Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD+ = asparagusate + H+ + NADH.
GO:0050446	azobenzene reductase activity	molecular_function	Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.
GO:0050447	zeatin 9-aminocarboxyethyltransferase activity	molecular_function	Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H+.
GO:0050448	beta-cyclopiazonate dehydrogenase activity	molecular_function	Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).
GO:0050449	casbene synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.
GO:0050450	citrate (Re)-synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.
GO:0050451	CoA-disulfide reductase (NADP) activity	molecular_function	Catalysis of the reaction: 2 CoA + NADP+ = CoA-disulfide + NADPH + H+.
GO:0050452	CoA-glutathione reductase (NADP) activity	molecular_function	Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.
GO:0050454	coenzyme F420 hydrogenase activity	molecular_function	Catalysis of the reaction: coenzyme F420 + H(2) + H+ = reduced coenzyme F420.
GO:0050455	columbamine oxidase activity	molecular_function	Catalysis of the reaction: 2 columbamine + O2 = 2 berberine + 2 H2O.
GO:0050456	cystine reductase activity	molecular_function	Catalysis of the reaction: 2 L-cysteine + NAD+ = L-cystine + H+ + NADH.
GO:0050457	decylcitrate synthase activity	molecular_function	Catalysis of the reaction: H2O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H+.
GO:0050458	decylhomocitrate synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + H2O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H+.
GO:0050459	ethanolamine-phosphate phospho-lyase activity	molecular_function	Catalysis of the reaction: H2O + phosphoethanolamine = acetaldehyde + NH4 + phosphate.
GO:0050460	hydroxylamine reductase (NADH) activity	molecular_function	Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.
GO:0050461	L-mimosine synthase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.
GO:0050462	N-acetylneuraminate synthase activity	molecular_function	Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.
GO:0050463	nitrate reductase [NAD(P)H] activity	molecular_function	Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.
GO:0050464	nitrate reductase (NADPH) activity	molecular_function	Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.
GO:0050465	nitroquinoline-N-oxide reductase activity	molecular_function	Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.
GO:0050467	pentalenene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.
GO:0050468	reticuline oxidase activity	molecular_function	Catalysis of the reaction: (S)-reticuline + O2 = (S)-scoulerine + H2O2 + H+.
GO:0050469	sabinene-hydrate synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + H2O = diphosphate + sabinene hydrate.
GO:0050470	trimethylamine dehydrogenase activity	molecular_function	Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.
GO:0050471	uracilylalanine synthase activity	molecular_function	Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.
GO:0050472	zeatin reductase activity	molecular_function	Catalysis of the reaction: dihydrozeatin + NADP+ = H+ + NADPH + zeatin.
GO:0050473	arachidonate 15-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
GO:0050474	(S)-norcoclaurine synthase activity	molecular_function	Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.
GO:0050476	acetylenedicarboxylate decarboxylase activity	molecular_function	Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.
GO:0050477	acyl-lysine deacylase activity	molecular_function	Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.
GO:0050479	glyceryl-ether monooxygenase activity	molecular_function	Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).
GO:0050480	imidazolonepropionase activity	molecular_function	Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H2O = N-formimidoyl-L-glutamate + H+.
GO:0050481	mandelate 4-monooxygenase activity	molecular_function	Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O2 = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H2O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.
GO:0050482	arachidonic acid secretion	biological_process	The controlled release of arachidonic acid from a cell or a tissue.
GO:0050483	IMP 5'-nucleotidase activity	molecular_function	Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate.
GO:0050484	GMP 5'-nucleotidase activity	molecular_function	Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate.
GO:0050485	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.
GO:0050486	intramolecular transferase activity, transferring hydroxy groups	molecular_function	Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.
GO:0050487	sulfoacetaldehyde acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.
GO:0050488	ecdysteroid UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.
GO:0050490	1,4-lactonase activity	molecular_function	Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.
GO:0050491	sulcatone reductase activity	molecular_function	Catalysis of the reaction: NAD+ + sulcatol = H+ + NADH + sulcatone.
GO:0050492	glycerol-1-phosphate dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.
GO:0050493	GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0050494	GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
GO:0050495	peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine	biological_process	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine.
GO:0050496	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine	biological_process	The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.
GO:0050497	alkylthioltransferase activity	molecular_function	Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).
GO:0050498	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.
GO:0050499	oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.
GO:0050500	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity	molecular_function	Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.
GO:0050501	hyaluronan synthase activity	molecular_function	Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.
GO:0050502	cis-zeatin O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H+ + UDP.
GO:0050503	trehalose 6-phosphate phosphorylase activity	molecular_function	Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.
GO:0050504	mannosyl-3-phosphoglycerate synthase activity	molecular_function	Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H+.
GO:0050505	hydroquinone glucosyltransferase activity	molecular_function	Catalysis of the reaction: hydroquinone + UDP-D-glucose = H+ + hydroquinone O-beta-D-glucopyranoside + UDP.
GO:0050506	vomilenine glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-glucose + vomilenine = H+ + raucaffricine + UDP.
GO:0050507	indoxyl-UDPG glucosyltransferase activity	molecular_function	Catalysis of the reaction: indoxyl + UDP-D-glucose = H+ + indican + UDP.
GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.
GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.
GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.
GO:0050511	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.
GO:0050512	lactosylceramide 4-alpha-galactosyltransferase activity	molecular_function	Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
GO:0050513	glycoprotein 2-beta-D-xylosyltransferase activity	molecular_function	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H+ + UDP.
GO:0050514	homospermidine synthase (spermidine-specific) activity	molecular_function	Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.
GO:0050515	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	molecular_function	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H+.
GO:0050518	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	molecular_function	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.
GO:0050519	holo-citrate lyase synthase activity	molecular_function	Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.
GO:0050520	phosphatidylcholine synthase activity	molecular_function	Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H+.
GO:0050521	alpha-glucan, water dikinase activity	molecular_function	Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate.
GO:0050522	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP.
GO:0050524	coenzyme-B sulfoethylthiotransferase activity	molecular_function	Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.
GO:0050525	cutinase activity	molecular_function	Catalysis of the reaction: cutin + H2O = cutin monomers.
GO:0050526	poly(3-hydroxybutyrate) depolymerase activity	molecular_function	Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.
GO:0050527	poly(3-hydroxyoctanoate) depolymerase activity	molecular_function	Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.
GO:0050528	acyloxyacyl hydrolase activity	molecular_function	Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.
GO:0050529	polyneuridine-aldehyde esterase activity	molecular_function	Catalysis of the reaction: H2O + polyneuridine aldehyde = 16-epivellosimine + CO2 + methanol.
GO:0050530	glucosylglycerol 3-phosphatase activity	molecular_function	Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H2O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.
GO:0050531	mannosyl-3-phosphoglycerate phosphatase activity	molecular_function	Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.
GO:0050532	2-phosphosulfolactate phosphatase activity	molecular_function	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H2O = (R)-3-sulfolactate + phosphate.
GO:0050533	5-phytase activity	molecular_function	Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.
GO:0050534	3-deoxyoctulosonase activity	molecular_function	Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.
GO:0050535	beta-primeverosidase activity	molecular_function	Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.
GO:0050536	(S)-N-acetyl-1-phenylethylamine hydrolase activity	molecular_function	Catalysis of the reaction: N-acetylphenylethylamine + H2O = acetate + phenylethylamine.
GO:0050537	mandelamide amidase activity	molecular_function	Catalysis of the reaction: (R)-mandelamide + H2O = (R)-mandelate + NH4.
GO:0050538	N-carbamoyl-L-amino-acid hydrolase activity	molecular_function	Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.
GO:0050539	maleimide hydrolase activity	molecular_function	Catalysis of the reaction: H2O + maleimide = H+ + maleamate.
GO:0050540	2-aminomuconate deaminase activity	molecular_function	Catalysis of the reaction: 2-aminomuconate + H2O + H+ = (Z)-5-oxohex-2-enedioate + NH4.
GO:0050541	beta,beta-carotene-9',10'-dioxygenase activity	molecular_function	Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.
GO:0050542	icosanoid binding	molecular_function	Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.
GO:0050543	icosatetraenoic acid binding	molecular_function	Binding to icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.
GO:0050544	arachidonic acid binding	molecular_function	Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
GO:0050545	sulfopyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-sulfopyruvate + H+ = CO2 + sulfoacetaldehyde.
GO:0050546	4-hydroxyphenylpyruvate decarboxylase activity	molecular_function	Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H+ = (4-hydroxyphenyl)acetaldehyde + CO2.
GO:0050547	vanillin synthase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.
GO:0050548	trans-feruloyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA.
GO:0050549	cyclohexyl-isocyanide hydratase activity	molecular_function	Catalysis of the reaction: N-cyclohexylformamide + H+ = cyclohexyl isocyanide + H2O.
GO:0050550	pinene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate.
GO:0050551	myrcene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.
GO:0050552	(4S)-limonene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.
GO:0050553	taxadiene synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.
GO:0050554	abietadiene synthase activity	molecular_function	Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.
GO:0050555	2-hydroxypropyl-CoM lyase activity	molecular_function	Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.
GO:0050556	deacetylisoipecoside synthase activity	molecular_function	Catalysis of the reaction: deacetylisoipecoside + H2O = dopamine + secologanin.
GO:0050557	deacetylipecoside synthase activity	molecular_function	Catalysis of the reaction: deacetylipecoside + H2O = dopamine + secologanin.
GO:0050558	maltose epimerase activity	molecular_function	Catalysis of the reaction: alpha-maltose = beta-maltose.
GO:0050559	copalyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.
GO:0050560	aspartate-tRNA(Asn) ligase activity	molecular_function	Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.
GO:0050561	glutamate-tRNA(Gln) ligase activity	molecular_function	Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.
GO:0050562	lysine-tRNA(Pyl) ligase activity	molecular_function	Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.
GO:0050563	trans-feruloyl-CoA synthase activity	molecular_function	Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate.
GO:0050564	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity	molecular_function	Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H2O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H+.
GO:0050565	aerobactin synthase activity	molecular_function	Catalysis of the reaction: ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine = aerobactin + AMP + diphosphate + H+.
GO:0050566	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.
GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.
GO:0050568	protein-glutamine glutaminase activity	molecular_function	Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.
GO:0050569	glycolaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: glycolaldehyde + H2O + NAD(+) = glycolate + 2 H+ + NADH.
GO:0050570	4-hydroxythreonine-4-phosphate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.
GO:0050571	1,5-anhydro-D-fructose reductase activity	molecular_function	Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.
GO:0050572	L-idonate 5-dehydrogenase activity	molecular_function	Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.
GO:0050573	dTDP-4-dehydro-6-deoxyglucose reductase activity	molecular_function	Catalysis of the reaction: dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H+ + NADPH.
GO:0050574	2-(R)-hydroxypropyl-CoM dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.
GO:0050575	2-(S)-hydroxypropyl-CoM dehydrogenase activity	molecular_function	Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.
GO:0050577	GDP-L-fucose synthase activity	molecular_function	Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.
GO:0050578	(R)-2-hydroxyacid dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+.
GO:0050579	vellosimine dehydrogenase activity	molecular_function	Catalysis of the reaction: 10-deoxysarpagine + NADP+ = H+ + NADPH + vellosimine.
GO:0050580	2,5-didehydrogluconate reductase activity	molecular_function	Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.
GO:0050581	D-mannitol oxidase activity	molecular_function	Catalysis of the reaction: mannitol + O2 = mannose + H2O2.
GO:0050582	xylitol oxidase activity	molecular_function	Catalysis of the reaction: xylitol + O2 = xylose + H2O2.
GO:0050583	hydrogen dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: NADP+ + H2 = NADPH + H+.
GO:0050584	linoleate 11-lipoxygenase activity	molecular_function	Catalysis of the reaction: linoleate + O2 = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.
GO:0050585	4-hydroxymandelate synthase activity	molecular_function	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.
GO:0050586	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity	molecular_function	Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H+ + O2 = N-acetylanthranilate + CO.
GO:0050587	chlorite O2-lyase activity	molecular_function	Catalysis of the reaction: chloride + O2 = chlorite.
GO:0050588	apo-beta-carotenoid-14',13'-dioxygenase activity	molecular_function	Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.
GO:0050589	leucocyanidin oxygenase activity	molecular_function	Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.
GO:0050590	desacetoxyvindoline 4-hydroxylase activity	molecular_function	Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.
GO:0050591	quinine 3-monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + quinine = 3-hydroxyquinine + H2O + NADP+.
GO:0050592	4-hydroxyphenylacetaldehyde oxime monooxygenase activity	molecular_function	Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H+ + NADPH + O2 = (S)-4-hydroxymandelonitrile + 2 H2O + NADP+.
GO:0050593	N-methylcoclaurine 3'-monooxygenase activity	molecular_function	Catalysis of the reaction: (S)-N-methylcoclaurine + H+ + NADPH + O2 = (S)-3'-hydroxy-N-methylcoclaurine + H2O + NADP+.
GO:0050594	tabersonine 16-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + tabersonine = 16-hydroxytabersonine + H2O + NADP+.
GO:0050595	7-deoxyloganin 7-hydroxylase activity	molecular_function	Catalysis of the reaction: 7-deoxyloganin + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganin + oxidized [NADPH-hemoprotein reductase].
GO:0050596	vinorine hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + vinorine = H2O + NADP+ + vomilenine.
GO:0050597	taxane 10-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP+.
GO:0050598	taxane 13-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-ol = H2O + NADP+ + taxa-4(20),11-dien-5alpha,13alpha-diol.
GO:0050599	deacetoxycephalosporin-C synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate.
GO:0050600	acyl-CoA 11-(E)-desaturase activity	molecular_function	Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11E)-delta11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.
GO:0050603	thiophene-2-carbonyl-CoA monooxygenase activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H+.
GO:0050604	taxadiene 5-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: AH(2) + O2 + taxa-4,11-diene = A + H2O + taxa-4(20),11-dien-5alpha-ol.
GO:0050605	superoxide reductase activity	molecular_function	Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.
GO:0050606	4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP+ = 2-oxo-2H-pyran-4,6-dicarboxylate + H+ + NADPH.
GO:0050607	mycothiol-dependent formaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.
GO:0050608	vanillin dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + vanillin = 2 H+ + NADH + vanillate.
GO:0050609	phosphonate dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + NAD+ + phosphonate = 2 H+ + NADH + phosphate.
GO:0050610	methylarsonate reductase activity	molecular_function	Catalysis of the reaction: 2 glutathione + H+ + methylarsonate = glutathione disulfide + H2O + methylarsonous acid.
GO:0050611	arsenate reductase (azurin) activity	molecular_function	Catalysis of the reaction: H2O + arsenite + 2 oxidized azurin = 2 H+ + 2 reduced azurin + arsenate.
GO:0050612	arsenate reductase (donor) activity	molecular_function	Catalysis of the reaction: A + arsenite + H2O = AH(2) + arsenate + 2 H+.
GO:0050613	delta14-sterol reductase activity	molecular_function	Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.
GO:0050614	delta24-sterol reductase activity	molecular_function	Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.
GO:0050615	1,2-dihydrovomilenine reductase activity	molecular_function	Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + H+ + NADPH.
GO:0050616	secologanin synthase activity	molecular_function	Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.
GO:0050617	15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
GO:0050618	phycoerythrobilin:ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.
GO:0050619	phytochromobilin:ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
GO:0050620	phycocyanobilin:ferredoxin oxidoreductase activity	molecular_function	Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
GO:0050621	tryptophan alpha,beta-oxidase activity	molecular_function	Catalysis of the reaction: L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2 + H+.
GO:0050622	glycine dehydrogenase (cyanide-forming) activity	molecular_function	Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.
GO:0050623	berberine reductase activity	molecular_function	Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + H+ + 2 NADPH.
GO:0050624	vomilenine reductase activity	molecular_function	Catalysis of the reaction: 1,2-dihydrovomilenine + NADP+ = H+ + NADPH + vomilenine.
GO:0050625	2-hydroxy-1,4-benzoquinone reductase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H+ + NADH = benzene-1,2,4-triol + NAD+.
GO:0050626	trimethylamine-N-oxide reductase (cytochrome c) activity	molecular_function	Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.
GO:0050627	mycothione reductase activity	molecular_function	Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.
GO:0050628	2-oxopropyl-CoM reductase (carboxylating) activity	molecular_function	Catalysis of the reaction: acetoacetate + coenzyme M + NADP+ = 2-oxopropyl-coenzyme M + CO2 + NADPH.
GO:0050629	tetrachloroethene reductive dehalogenase activity	molecular_function	Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor.
GO:0050630	(iso)eugenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.
GO:0050631	corydaline synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP+.
GO:0050632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	molecular_function	Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.
GO:0050633	acetyl-CoA C-myristoyltransferase activity	molecular_function	Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.
GO:0050634	phloroisovalerophenone synthase activity	molecular_function	Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.
GO:0050635	acridone synthase activity	molecular_function	Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H+ + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O.
GO:0050636	vinorine synthase activity	molecular_function	Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.
GO:0050637	lovastatin nonaketide synthase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+.
GO:0050638	taxadien-5-alpha-ol O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.
GO:0050639	10-hydroxytaxane O-acetyltransferase activity	molecular_function	Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.
GO:0050640	isopenicillin-N N-acyltransferase activity	molecular_function	Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.
GO:0050641	6-methylsalicylic acid synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+.
GO:0050642	2-alpha-hydroxytaxane 2-O-benzoyltransferase activity	molecular_function	Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.
GO:0050643	10-deacetylbaccatin III 10-O-acetyltransferase activity	molecular_function	Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.
GO:0050644	cis-p-coumarate glucosyltransferase activity	molecular_function	Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H+ + UDP.
GO:0050645	limonoid glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.
GO:0050646	5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding	molecular_function	Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
GO:0050647	5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	molecular_function	Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
GO:0050648	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	molecular_function	Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
GO:0050649	testosterone 6-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O.
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological_process	The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.
GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	biological_process	The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.
GO:0050654	chondroitin sulfate proteoglycan metabolic process	biological_process	The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
GO:0050655	dermatan sulfate proteoglycan metabolic process	biological_process	The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	molecular_function	Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
GO:0050657	nucleic acid transport	biological_process	The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0050658	RNA transport	biological_process	The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	molecular_function	Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
GO:0050660	flavin adenine dinucleotide binding	molecular_function	Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
GO:0050661	NADP binding	molecular_function	Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.
GO:0050665	hydrogen peroxide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
GO:0050666	regulation of homocysteine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.
GO:0050667	homocysteine metabolic process	biological_process	The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.
GO:0050668	positive regulation of homocysteine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
GO:0050669	negative regulation of homocysteine metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
GO:0050670	regulation of lymphocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of lymphocyte proliferation.
GO:0050671	positive regulation of lymphocyte proliferation	biological_process	Any process that activates or increases the rate or extent of lymphocyte proliferation.
GO:0050672	negative regulation of lymphocyte proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.
GO:0050673	epithelial cell proliferation	biological_process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
GO:0050674	urothelial cell proliferation	biological_process	The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.
GO:0050675	regulation of urothelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of urothelial cell proliferation.
GO:0050676	negative regulation of urothelial cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.
GO:0050677	positive regulation of urothelial cell proliferation	biological_process	Any process that activates or increases the rate or extent of urothelial cell proliferation.
GO:0050678	regulation of epithelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell proliferation.
GO:0050679	positive regulation of epithelial cell proliferation	biological_process	Any process that activates or increases the rate or extent of epithelial cell proliferation.
GO:0050680	negative regulation of epithelial cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
GO:0050681	nuclear androgen receptor binding	molecular_function	Binding to a nuclear androgen receptor.
GO:0050682	AF-2 domain binding	molecular_function	Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.
GO:0050683	AF-1 domain binding	molecular_function	Binding to an AF-1 protein domain, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.
GO:0050684	regulation of mRNA processing	biological_process	Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
GO:0050685	positive regulation of mRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA processing.
GO:0050686	negative regulation of mRNA processing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.
GO:0050687	negative regulation of defense response to virus	biological_process	Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
GO:0050688	regulation of defense response to virus	biological_process	Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
GO:0050689	negative regulation of defense response to virus by host	biological_process	Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0050691	regulation of defense response to virus by host	biological_process	Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.
GO:0050692	DNA binding domain binding	molecular_function	Binding to a protein's DNA binding domain (DBD).
GO:0050693	LBD domain binding	molecular_function	Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.
GO:0050694	galactose 3-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.
GO:0050695	benzoylformate decarboxylase activity	molecular_function	Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.
GO:0050696	trichloroethylene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
GO:0050697	1,1,2-trichloroethene reductive dehalogenase activity	molecular_function	Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.
GO:0050698	proteoglycan sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
GO:0050699	WW domain binding	molecular_function	Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
GO:0050700	CARD domain binding	molecular_function	Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
GO:0050708	regulation of protein secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
GO:0050709	negative regulation of protein secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
GO:0050714	positive regulation of protein secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
GO:0050727	regulation of inflammatory response	biological_process	Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
GO:0050728	negative regulation of inflammatory response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
GO:0050729	positive regulation of inflammatory response	biological_process	Any process that activates or increases the frequency, rate or extent of the inflammatory response.
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
GO:0050733	RS domain binding	molecular_function	Binding to an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.
GO:0050734	hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.
GO:0050735	N-malonyltransferase activity	molecular_function	Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.
GO:0050736	O-malonyltransferase activity	molecular_function	Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.
GO:0050737	O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.
GO:0050738	fructosyltransferase activity	molecular_function	Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0050739	peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium	biological_process	The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium.
GO:0050745	peptide cross-linking via L-cysteinyl-5-imidazolinone glycine	biological_process	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.
GO:0050746	regulation of lipoprotein metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0050747	positive regulation of lipoprotein metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0050748	negative regulation of lipoprotein metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
GO:0050750	low-density lipoprotein particle receptor binding	molecular_function	Binding to a low-density lipoprotein receptor.
GO:0050761	depsipeptide metabolic process	biological_process	The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
GO:0050762	depsipeptide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
GO:0050763	depsipeptide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
GO:0050764	regulation of phagocytosis	biological_process	Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.
GO:0050765	negative regulation of phagocytosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.
GO:0050766	positive regulation of phagocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of phagocytosis.
GO:0050767	regulation of neurogenesis	biological_process	Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.
GO:0050768	negative regulation of neurogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
GO:0050769	positive regulation of neurogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
GO:0050770	regulation of axonogenesis	biological_process	Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
GO:0050771	negative regulation of axonogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.
GO:0050772	positive regulation of axonogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of axonogenesis.
GO:0050773	regulation of dendrite development	biological_process	Any process that modulates the frequency, rate or extent of dendrite development.
GO:0050774	negative regulation of dendrite morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
GO:0050775	positive regulation of dendrite morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
GO:0050776	regulation of immune response	biological_process	Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GO:0050777	negative regulation of immune response	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GO:0050778	positive regulation of immune response	biological_process	Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
GO:0050779	RNA destabilization	biological_process	Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.
GO:0050780	dopamine receptor binding	molecular_function	Binding to a dopamine receptor.
GO:0050781	ortho-trichlorophenol reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.
GO:0050782	galactose uniporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).
GO:0050783	cocaine metabolic process	biological_process	The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
GO:0050784	cocaine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
GO:0050785	advanced glycation end-product receptor activity	molecular_function	Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
GO:0050786	RAGE receptor binding	molecular_function	Binding to a RAGE receptor, the receptor for advanced glycation end-products.
GO:0050787	detoxification of mercury ion	biological_process	Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).
GO:0050788	sequestering of mercury	biological_process	The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.
GO:0050789	regulation of biological process	biological_process	Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0050790	regulation of catalytic activity	biological_process	Any process that modulates the activity of an enzyme.
GO:0050792	regulation of viral process	biological_process	Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.
GO:0050793	regulation of developmental process	biological_process	Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0050794	regulation of cellular process	biological_process	Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050795	regulation of behavior	biological_process	Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
GO:0050796	regulation of insulin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of insulin.
GO:0050797	thymidylate synthase (FAD) activity	molecular_function	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.
GO:0050798	activated T cell proliferation	biological_process	The expansion of a T cell population following activation by an antigenic stimulus.
GO:0050799	cocaine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
GO:0050801	monoatomic ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0050802	circadian sleep/wake cycle, sleep	biological_process	The part of the circadian sleep/wake cycle where the organism is asleep.
GO:0050803	regulation of synapse structure or activity	biological_process	Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
GO:0050804	modulation of chemical synaptic transmission	biological_process	Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
GO:0050805	negative regulation of synaptic transmission	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
GO:0050806	positive regulation of synaptic transmission	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
GO:0050807	regulation of synapse organization	biological_process	Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
GO:0050808	synapse organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
GO:0050809	diazepam binding	molecular_function	Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.
GO:0050810	regulation of steroid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
GO:0050811	GABA receptor binding	molecular_function	Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
GO:0050812	regulation of acyl-CoA biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.
GO:0050813	epothilone metabolic process	biological_process	The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.
GO:0050814	epothilone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.
GO:0050815	phosphoserine residue binding	molecular_function	Binding to a phosphorylated serine residue within a protein.
GO:0050816	phosphothreonine residue binding	molecular_function	Binding to a phosphorylated threonine residue within a protein.
GO:0050817	coagulation	biological_process	The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
GO:0050818	regulation of coagulation	biological_process	Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
GO:0050819	negative regulation of coagulation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
GO:0050820	positive regulation of coagulation	biological_process	Any process that activates or increases the frequency, rate or extent of coagulation.
GO:0050821	protein stabilization	biological_process	Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
GO:0050822	peptide stabilization	biological_process	Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.
GO:0050823	peptide antigen stabilization	biological_process	Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
GO:0050825	ice binding	molecular_function	Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.
GO:0050826	response to freezing	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
GO:0050829	defense response to Gram-negative bacterium	biological_process	Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
GO:0050830	defense response to Gram-positive bacterium	biological_process	Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
GO:0050831	male-specific defense response to bacterium	biological_process	A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.
GO:0050832	defense response to fungus	biological_process	Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
GO:0050833	pyruvate transmembrane transporter activity	molecular_function	Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.
GO:0050834	molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	biological_process	The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.
GO:0050835	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.
GO:0050836	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide	biological_process	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.
GO:0050837	peptide cross-linking via L-cysteinyl-L-selenocysteine	biological_process	The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P.
GO:0050838	peptidyl-5-hydroxy-L-lysine trimethylation	biological_process	The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.
GO:0050839	cell adhesion molecule binding	molecular_function	Binding to a cell adhesion molecule.
GO:0050840	extracellular matrix binding	molecular_function	Binding to a component of the extracellular matrix.
GO:0050841	peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine	biological_process	The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.
GO:0050842	copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	biological_process	The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.
GO:0050843	S-adenosylmethionine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
GO:0050844	peptidyl-selenocysteine modification	biological_process	The modification of peptidyl-selenocysteine.
GO:0050845	teichuronic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.
GO:0050846	teichuronic acid metabolic process	biological_process	The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.
GO:0050847	progesterone receptor signaling pathway	biological_process	The series of molecular signals initiated by progesterone binding to its receptor in the cytoplasm.
GO:0050848	regulation of calcium-mediated signaling	biological_process	Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
GO:0050849	negative regulation of calcium-mediated signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
GO:0050850	positive regulation of calcium-mediated signaling	biological_process	Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.
GO:0050851	antigen receptor-mediated signaling pathway	biological_process	The series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.
GO:0050852	T cell receptor signaling pathway	biological_process	The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
GO:0050853	B cell receptor signaling pathway	biological_process	The series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
GO:0050854	regulation of antigen receptor-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
GO:0050855	regulation of B cell receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
GO:0050856	regulation of T cell receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
GO:0050859	negative regulation of B cell receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
GO:0050860	negative regulation of T cell receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
GO:0050861	positive regulation of B cell receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
GO:0050862	positive regulation of T cell receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
GO:0050863	regulation of T cell activation	biological_process	Any process that modulates the frequency, rate or extent of T cell activation.
GO:0050864	regulation of B cell activation	biological_process	Any process that modulates the frequency, rate or extent of B cell activation.
GO:0050865	regulation of cell activation	biological_process	Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0050866	negative regulation of cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
GO:0050867	positive regulation of cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of activation.
GO:0050868	negative regulation of T cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
GO:0050869	negative regulation of B cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
GO:0050870	positive regulation of T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of T cell activation.
GO:0050871	positive regulation of B cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of B cell activation.
GO:0050872	white fat cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
GO:0050873	brown fat cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
GO:0050877	nervous system process	biological_process	A organ system process carried out by any of the organs or tissues of neurological system.
GO:0050878	regulation of body fluid levels	biological_process	Any process that modulates the levels of body fluids.
GO:0050879	multicellular organismal movement	biological_process	Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.
GO:0050881	musculoskeletal movement	biological_process	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.
GO:0050882	voluntary musculoskeletal movement	biological_process	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.
GO:0050883	musculoskeletal movement, spinal reflex action	biological_process	Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.
GO:0050884	neuromuscular process controlling posture	biological_process	Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
GO:0050885	neuromuscular process controlling balance	biological_process	Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
GO:0050886	endocrine process	biological_process	The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
GO:0050887	determination of sensory modality	biological_process	The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.
GO:0050888	determination of stimulus location	biological_process	The determination of where on the body surface, within the body or in the environment a stimulus originates.
GO:0050889	determination of stimulus intensity	biological_process	The determination of the perceived strength of a sensory stimulus.
GO:0050890	cognition	biological_process	The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
GO:0050891	multicellular organismal-level water homeostasis	biological_process	A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
GO:0050892	intestinal absorption	biological_process	Any process in which nutrients are taken up from the contents of the intestine.
GO:0050893	sensory processing	biological_process	Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.
GO:0050894	determination of affect	biological_process	Any process in which an emotional response is associated with a particular sensory stimulation.
GO:0050896	response to stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0050897	cobalt ion binding	molecular_function	Binding to a cobalt ion (Co).
GO:0050898	nitrile metabolic process	biological_process	The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.
GO:0050899	nitrile catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.
GO:0050900	leukocyte migration	biological_process	The movement of a leukocyte within or between different tissues and organs of the body.
GO:0050901	leukocyte tethering or rolling	biological_process	Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).
GO:0050902	leukocyte adhesive activation	biological_process	The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.
GO:0050903	leukocyte activation-dependent arrest	biological_process	The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.
GO:0050904	diapedesis	biological_process	The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
GO:0050905	neuromuscular process	biological_process	Any process pertaining to the functions of the nervous and muscular systems of an organism.
GO:0050906	detection of stimulus involved in sensory perception	biological_process	The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.
GO:0050907	detection of chemical stimulus involved in sensory perception	biological_process	The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.
GO:0050908	detection of light stimulus involved in visual perception	biological_process	The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
GO:0050909	sensory perception of taste	biological_process	The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	biological_process	The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	biological_process	The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	biological_process	The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.
GO:0050913	sensory perception of bitter taste	biological_process	The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050914	sensory perception of salty taste	biological_process	The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050915	sensory perception of sour taste	biological_process	The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050916	sensory perception of sweet taste	biological_process	The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050917	sensory perception of umami taste	biological_process	The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.
GO:0050918	positive chemotaxis	biological_process	The directed movement of a motile cell or organism towards a higher concentration of a chemical.
GO:0050919	negative chemotaxis	biological_process	The directed movement of a motile cell or organism towards a lower concentration of a chemical.
GO:0050920	regulation of chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
GO:0050921	positive regulation of chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
GO:0050922	negative regulation of chemotaxis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
GO:0050923	regulation of negative chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
GO:0050924	positive regulation of negative chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
GO:0050925	negative regulation of negative chemotaxis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
GO:0050926	regulation of positive chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
GO:0050927	positive regulation of positive chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
GO:0050928	negative regulation of positive chemotaxis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
GO:0050929	induction of negative chemotaxis	biological_process	Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
GO:0050930	induction of positive chemotaxis	biological_process	Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
GO:0050931	pigment cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.
GO:0050932	regulation of pigment cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of pigmented cell differentiation.
GO:0050933	early stripe melanocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).
GO:0050934	late stripe melanocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).
GO:0050935	iridophore differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.
GO:0050936	xanthophore differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.
GO:0050937	regulation of iridophore differentiation	biological_process	Any process that modulates the frequency, rate or extent of iridophore differentiation.
GO:0050938	regulation of xanthophore differentiation	biological_process	Any process that modulates the frequency, rate or extent of xanthophore differentiation.
GO:0050939	regulation of early stripe melanocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.
GO:0050940	regulation of late stripe melanocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.
GO:0050941	negative regulation of pigment cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.
GO:0050942	positive regulation of pigment cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.
GO:0050943	negative regulation of iridophore differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.
GO:0050944	negative regulation of xanthophore differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.
GO:0050945	positive regulation of iridophore differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of iridophore differentiation.
GO:0050946	positive regulation of xanthophore differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.
GO:0050947	negative regulation of early stripe melanocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.
GO:0050948	positive regulation of early stripe melanocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.
GO:0050949	negative regulation of late stripe melanocyte differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.
GO:0050950	positive regulation of late stripe melanocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.
GO:0050951	sensory perception of temperature stimulus	biological_process	The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050952	sensory perception of electrical stimulus	biological_process	The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050953	sensory perception of light stimulus	biological_process	The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050954	sensory perception of mechanical stimulus	biological_process	The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0050955	thermoception	biological_process	The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).
GO:0050956	electroception	biological_process	The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.
GO:0050957	equilibrioception	biological_process	The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.
GO:0050958	magnetoreception	biological_process	The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.
GO:0050959	echolocation	biological_process	Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.
GO:0050960	detection of temperature stimulus involved in thermoception	biological_process	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.
GO:0050961	detection of temperature stimulus involved in sensory perception	biological_process	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.
GO:0050962	detection of light stimulus involved in sensory perception	biological_process	The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.
GO:0050963	detection of electrical stimulus involved in sensory perception	biological_process	The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.
GO:0050964	detection of electrical stimulus involved in electroception	biological_process	The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	biological_process	The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	biological_process	The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
GO:0050967	detection of electrical stimulus involved in sensory perception of pain	biological_process	The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	biological_process	The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.
GO:0050969	detection of chemical stimulus involved in magnetoreception	biological_process	The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.
GO:0050970	detection of electrical stimulus involved in magnetoreception	biological_process	The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.
GO:0050971	detection of mechanical stimulus involved in magnetoreception	biological_process	The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.
GO:0050972	detection of mechanical stimulus involved in echolocation	biological_process	The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.
GO:0050973	detection of mechanical stimulus involved in equilibrioception	biological_process	The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.
GO:0050974	detection of mechanical stimulus involved in sensory perception	biological_process	The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
GO:0050975	sensory perception of touch	biological_process	The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).
GO:0050976	detection of mechanical stimulus involved in sensory perception of touch	biological_process	The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
GO:0050977	magnetoreception by sensory perception of chemical stimulus	biological_process	The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.
GO:0050978	magnetoreception by sensory perception of electrical stimulus	biological_process	The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.
GO:0050979	magnetoreception by sensory perception of mechanical stimulus	biological_process	The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.
GO:0050980	detection of light stimulus involved in magnetoreception	biological_process	The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.
GO:0050981	detection of electrical stimulus	biological_process	The series of events by which an electrical stimulus is received and converted into a molecular signal.
GO:0050982	detection of mechanical stimulus	biological_process	The series of events by which a mechanical stimulus is received and converted into a molecular signal.
GO:0050984	peptidyl-serine sulfation	biological_process	The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.
GO:0050985	peptidyl-threonine sulfation	biological_process	The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.
GO:0050986	isopeptide cross-linking via N-(L-isoglutamyl)-glycine	biological_process	The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.
GO:0050988	N-terminal peptidyl-methionine carboxylation	biological_process	The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.
GO:0050989	N-terminal protein amino acid carboxylation	biological_process	The carboxylation of the N-terminal amino acid of proteins.
GO:0050990	N-terminal protein amino acid carbamoylation	biological_process	The carbamoylation of the N-terminal amino acid of proteins.
GO:0050992	dimethylallyl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.
GO:0050993	dimethylallyl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving dimethylallyl diphosphate.
GO:0050994	regulation of lipid catabolic process	biological_process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GO:0050995	negative regulation of lipid catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GO:0050996	positive regulation of lipid catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GO:0050997	quaternary ammonium group binding	molecular_function	Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
GO:0050998	nitric-oxide synthase binding	molecular_function	Binding to nitric-oxide synthase.
GO:0050999	regulation of nitric-oxide synthase activity	biological_process	Any process that modulates the activity of the enzyme nitric-oxide synthase.
GO:0051000	positive regulation of nitric-oxide synthase activity	biological_process	Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
GO:0051001	negative regulation of nitric-oxide synthase activity	biological_process	Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.
GO:0051002	ligase activity, forming nitrogen-metal bonds	molecular_function	Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0051003	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	molecular_function	Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.
GO:0051004	regulation of lipoprotein lipase activity	biological_process	Any process that modulates the activity of the enzyme lipoprotein lipase.
GO:0051005	negative regulation of lipoprotein lipase activity	biological_process	Any process that stops or reduces the activity of the enzyme lipoprotein lipase.
GO:0051006	positive regulation of lipoprotein lipase activity	biological_process	Any process that activates or increases the activity of the enzyme lipoprotein lipase.
GO:0051007	squalene-hopene cyclase activity	molecular_function	Catalysis of the reaction: squalene = hop-22(29)-ene.
GO:0051008	Hsp27 protein binding	molecular_function	Binding to Hsp27 proteins, a lightweight heat shock protein.
GO:0051009	O-acetylhomoserine sulfhydrylase activity	molecular_function	Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.
GO:0051010	microtubule plus-end binding	molecular_function	Binding to the plus end of a microtubule.
GO:0051011	microtubule minus-end binding	molecular_function	Binding to the minus end of a microtubule.
GO:0051012	microtubule sliding	biological_process	The movement of one microtubule along another microtubule.
GO:0051013	microtubule severing	biological_process	The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.
GO:0051014	actin filament severing	biological_process	The process in which an actin filament is broken down into smaller filaments.
GO:0051015	actin filament binding	molecular_function	Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
GO:0051016	barbed-end actin filament capping	biological_process	The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
GO:0051017	actin filament bundle assembly	biological_process	The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
GO:0051018	protein kinase A binding	molecular_function	Binding to a protein kinase A.
GO:0051019	mitogen-activated protein kinase binding	molecular_function	Binding to a mitogen-activated protein kinase.
GO:0051020	GTPase binding	molecular_function	Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
GO:0051021	GDP-dissociation inhibitor binding	molecular_function	Binding to a GDP-dissociation inhibitor protein.
GO:0051022	Rho GDP-dissociation inhibitor binding	molecular_function	Binding to a Rho GDP-dissociation inhibitor protein.
GO:0051026	chiasma assembly	biological_process	The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.
GO:0051027	DNA transport	biological_process	The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051028	mRNA transport	biological_process	The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051029	rRNA transport	biological_process	The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051030	snRNA transport	biological_process	The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051031	tRNA transport	biological_process	The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051032	nucleic acid transmembrane transporter activity	molecular_function	Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.
GO:0051033	RNA transmembrane transporter activity	molecular_function	Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.
GO:0051034	tRNA transmembrane transporter activity	molecular_function	Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.
GO:0051035	DNA transmembrane transporter activity	molecular_function	Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.
GO:0051036	regulation of endosome size	biological_process	Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.
GO:0051037	regulation of transcription involved in meiotic cell cycle	biological_process	Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.
GO:0051038	negative regulation of transcription involved in meiotic cell cycle	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.
GO:0051039	positive regulation of transcription involved in meiotic cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
GO:0051040	regulation of calcium-independent cell-cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.
GO:0051042	negative regulation of calcium-independent cell-cell adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.
GO:0051043	regulation of membrane protein ectodomain proteolysis	biological_process	Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	biological_process	Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.
GO:0051046	regulation of secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GO:0051047	positive regulation of secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GO:0051048	negative regulation of secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GO:0051049	regulation of transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051050	positive regulation of transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051051	negative regulation of transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051052	regulation of DNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GO:0051053	negative regulation of DNA metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GO:0051054	positive regulation of DNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GO:0051055	negative regulation of lipid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GO:0051056	regulation of small GTPase mediated signal transduction	biological_process	Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
GO:0051057	positive regulation of small GTPase mediated signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
GO:0051058	negative regulation of small GTPase mediated signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.
GO:0051059	NF-kappaB binding	molecular_function	Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
GO:0051060	pullulanase activity	molecular_function	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.
GO:0051061	ADP reductase activity	molecular_function	Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.
GO:0051062	UDP reductase activity	molecular_function	Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.
GO:0051063	CDP reductase activity	molecular_function	Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.
GO:0051064	TTP reductase activity	molecular_function	Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0051065	CTP reductase activity	molecular_function	Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0051066	dihydrobiopterin metabolic process	biological_process	The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.
GO:0051067	dihydropteridine metabolic process	biological_process	The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.
GO:0051068	dihydrolipoamide metabolic process	biological_process	The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.
GO:0051069	galactomannan metabolic process	biological_process	The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.
GO:0051070	galactomannan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.
GO:0051071	4,6-pyruvylated galactose residue metabolic process	biological_process	The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.
GO:0051072	4,6-pyruvylated galactose residue biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.
GO:0051073	adenosylcobinamide-GDP ribazoletransferase activity	molecular_function	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.
GO:0051075	S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity	molecular_function	Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.
GO:0051077	secondary cell septum	cellular_component	Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.
GO:0051078	meiotic nuclear membrane disassembly	biological_process	The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.
GO:0051079	meiosis I nuclear membrane disassembly	biological_process	The controlled breakdown of the nuclear membranes during the first division of meiosis.
GO:0051080	meiosis II nuclear membrane disassembly	biological_process	The controlled breakdown of the nuclear membranes during the second division of meiosis.
GO:0051081	nuclear membrane disassembly	biological_process	The controlled breakdown of the nuclear membranes, for example during cellular division.
GO:0051082	unfolded protein binding	molecular_function	Binding to an unfolded protein.
GO:0051083	'de novo' cotranslational protein folding	biological_process	The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.
GO:0051084	'de novo' post-translational protein folding	biological_process	The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.
GO:0051085	chaperone cofactor-dependent protein refolding	biological_process	The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
GO:0051086	chaperone mediated protein folding independent of cofactor	biological_process	The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.
GO:0051087	protein-folding chaperone binding	molecular_function	Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
GO:0051089	constitutive protein ectodomain proteolysis	biological_process	The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.
GO:0051090	regulation of DNA-binding transcription factor activity	biological_process	Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GO:0051091	positive regulation of DNA-binding transcription factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GO:0051092	positive regulation of NF-kappaB transcription factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
GO:0051093	negative regulation of developmental process	biological_process	Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0051094	positive regulation of developmental process	biological_process	Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0051095	regulation of helicase activity	biological_process	Any process that modulates the frequency, rate or extent of helicase activity.
GO:0051096	positive regulation of helicase activity	biological_process	Any process that activates or increases the activity of a helicase.
GO:0051097	negative regulation of helicase activity	biological_process	Any process that stops or reduces the activity of a helicase.
GO:0051098	regulation of binding	biological_process	Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GO:0051099	positive regulation of binding	biological_process	Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GO:0051100	negative regulation of binding	biological_process	Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GO:0051101	regulation of DNA binding	biological_process	Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO:0051102	DNA ligation involved in DNA recombination	biological_process	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.
GO:0051103	DNA ligation involved in DNA repair	biological_process	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.
GO:0051104	DNA-dependent DNA replication DNA ligation	biological_process	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.
GO:0051105	regulation of DNA ligation	biological_process	Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
GO:0051106	positive regulation of DNA ligation	biological_process	Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
GO:0051107	negative regulation of DNA ligation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
GO:0051108	carnitine-CoA ligase activity	molecular_function	Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.
GO:0051109	crotonobetaine-CoA ligase activity	molecular_function	Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.
GO:0051110	peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine	biological_process	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).
GO:0051111	peptidyl-histidine adenylylation	biological_process	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).
GO:0051112	peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine	biological_process	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).
GO:0051114	peptidyl-histidine uridylylation	biological_process	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).
GO:0051116	cobaltochelatase activity	molecular_function	Catalysis of the reaction: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H+ + phosphate.
GO:0051117	ATPase binding	molecular_function	Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
GO:0051118	glucan endo-1,3-alpha-glucosidase activity	molecular_function	Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.
GO:0051119	sugar transmembrane transporter activity	molecular_function	Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
GO:0051120	hepoxilin A3 synthase activity	molecular_function	Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
GO:0051121	hepoxilin metabolic process	biological_process	The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
GO:0051122	hepoxilin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
GO:0051123	RNA polymerase II preinitiation complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
GO:0051124	synaptic assembly at neuromuscular junction	biological_process	The assembly of a synapse at a neuromuscular junction.
GO:0051125	regulation of actin nucleation	biological_process	Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
GO:0051126	negative regulation of actin nucleation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
GO:0051127	positive regulation of actin nucleation	biological_process	Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
GO:0051128	regulation of cellular component organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0051129	negative regulation of cellular component organization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0051130	positive regulation of cellular component organization	biological_process	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0051131	chaperone-mediated protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
GO:0051132	NK T cell activation	biological_process	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0051133	regulation of NK T cell activation	biological_process	Any process that modulates the frequency, rate or extent of natural killer T cell activation.
GO:0051134	negative regulation of NK T cell activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.
GO:0051135	positive regulation of NK T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.
GO:0051136	regulation of NK T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.
GO:0051137	negative regulation of NK T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.
GO:0051138	positive regulation of NK T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.
GO:0051139	metal cation:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).
GO:0051140	regulation of NK T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.
GO:0051141	negative regulation of NK T cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.
GO:0051142	positive regulation of NK T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.
GO:0051143	propanediol metabolic process	biological_process	The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.
GO:0051144	propanediol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.
GO:0051145	smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
GO:0051146	striated muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
GO:0051147	regulation of muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of muscle cell differentiation.
GO:0051148	negative regulation of muscle cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.
GO:0051149	positive regulation of muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.
GO:0051150	regulation of smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.
GO:0051151	negative regulation of smooth muscle cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
GO:0051152	positive regulation of smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.
GO:0051153	regulation of striated muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.
GO:0051154	negative regulation of striated muscle cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
GO:0051155	positive regulation of striated muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.
GO:0051156	glucose 6-phosphate metabolic process	biological_process	The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
GO:0051157	arabitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
GO:0051158	L-arabitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
GO:0051159	D-arabitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
GO:0051160	L-xylitol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.
GO:0051161	arabitol metabolic process	biological_process	The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
GO:0051162	L-arabitol metabolic process	biological_process	The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
GO:0051163	D-arabitol metabolic process	biological_process	The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
GO:0051164	L-xylitol metabolic process	biological_process	The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.
GO:0051165	2,5-dihydroxypyridine metabolic process	biological_process	The chemical reactions and pathways involving 2,5-dihydroxypyridine.
GO:0051166	2,5-dihydroxypyridine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.
GO:0051167	xylulose 5-phosphate metabolic process	biological_process	The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.
GO:0051168	nuclear export	biological_process	The directed movement of substances out of the nucleus.
GO:0051169	nuclear transport	biological_process	The directed movement of substances into, out of, or within the nucleus.
GO:0051170	import into nucleus	biological_process	The directed movement of substances into the nucleus.
GO:0051171	regulation of nitrogen compound metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GO:0051172	negative regulation of nitrogen compound metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GO:0051173	positive regulation of nitrogen compound metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GO:0051174	regulation of phosphorus metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
GO:0051175	negative regulation of sulfur metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GO:0051176	positive regulation of sulfur metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GO:0051177	meiotic sister chromatid cohesion	biological_process	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.
GO:0051179	localization	biological_process	Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0051180	vitamin transport	biological_process	The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
GO:0051189	prosthetic group metabolic process	biological_process	The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
GO:0051190	prosthetic group catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
GO:0051191	prosthetic group biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
GO:0051192	prosthetic group binding	molecular_function	Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
GO:0051202	phytochromobilin metabolic process	biological_process	The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.
GO:0051203	peptidyl-aspartic acid reduction to form L-aspartyl aldehyde	biological_process	The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.
GO:0051204	protein insertion into mitochondrial membrane	biological_process	The process that results in the incorporation of a protein into a mitochondrial membrane.
GO:0051205	protein insertion into membrane	biological_process	The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
GO:0051206	silicate metabolic process	biological_process	The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
GO:0051208	sequestering of calcium ion	biological_process	The process of binding or confining calcium ions such that they are separated from other components of a biological system.
GO:0051209	release of sequestered calcium ion into cytosol	biological_process	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
GO:0051210	isotropic cell growth	biological_process	The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.
GO:0051211	anisotropic cell growth	biological_process	The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.
GO:0051212	vanadium ion binding	molecular_function	Binding to a vanadium ion (V).
GO:0051213	dioxygenase activity	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.
GO:0051214	RNAi-mediated antiviral immunity against RNA virus	biological_process	An RNAi-mediated post-transcriptional gene silencing pathway induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL4 is the primary Dicer to detect RNA viruses.
GO:0051215	RNAi-mediated antiviral immunity against DNA virus	biological_process	An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses.
GO:0051216	cartilage development	biological_process	The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0051217	molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)	biological_process	The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).
GO:0051218	tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)	biological_process	The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).
GO:0051219	phosphoprotein binding	molecular_function	Binding to a phosphorylated protein.
GO:0051220	cytoplasmic sequestering of protein	biological_process	The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.
GO:0051221	tungsten incorporation into metallo-sulfur cluster	biological_process	The incorporation of tungsten into a metallo-sulfur cluster.
GO:0051222	positive regulation of protein transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051223	regulation of protein transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051224	negative regulation of protein transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051225	spindle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0051228	mitotic spindle disassembly	biological_process	The controlled breakdown of the spindle during a mitotic cell cycle.
GO:0051229	meiotic spindle disassembly	biological_process	The controlled breakdown of the spindle during a meiotic cell cycle.
GO:0051230	spindle disassembly	biological_process	The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0051231	spindle elongation	biological_process	The cell cycle process in which the distance is lengthened between poles of the spindle.
GO:0051232	meiotic spindle elongation	biological_process	The lengthening of the distance between poles of the spindle during a meiotic cell cycle.
GO:0051233	spindle midzone	cellular_component	The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
GO:0051234	establishment of localization	biological_process	Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051235	maintenance of location	biological_process	Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.
GO:0051236	establishment of RNA localization	biological_process	The directed movement of RNA to a specific location.
GO:0051237	maintenance of RNA location	biological_process	Any process in which RNA is maintained in a location and prevented from moving elsewhere.
GO:0051238	sequestering of metal ion	biological_process	The process of binding or confining metal ions such that they are separated from other components of a biological system.
GO:0051239	regulation of multicellular organismal process	biological_process	Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
GO:0051240	positive regulation of multicellular organismal process	biological_process	Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GO:0051241	negative regulation of multicellular organismal process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GO:0051245	negative regulation of cellular defense response	biological_process	Any process that stops, prevents, or reduces the rate of the cellular defense response.
GO:0051246	regulation of protein metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GO:0051247	positive regulation of protein metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GO:0051248	negative regulation of protein metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
GO:0051249	regulation of lymphocyte activation	biological_process	Any process that modulates the frequency, rate or extent of lymphocyte activation.
GO:0051250	negative regulation of lymphocyte activation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.
GO:0051251	positive regulation of lymphocyte activation	biological_process	Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
GO:0051252	regulation of RNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0051253	negative regulation of RNA metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0051254	positive regulation of RNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GO:0051255	spindle midzone assembly	biological_process	The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
GO:0051256	mitotic spindle midzone assembly	biological_process	The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.
GO:0051257	meiotic spindle midzone assembly	biological_process	The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.
GO:0051258	protein polymerization	biological_process	The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.
GO:0051259	protein complex oligomerization	biological_process	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO:0051260	protein homooligomerization	biological_process	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO:0051261	protein depolymerization	biological_process	The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
GO:0051262	protein tetramerization	biological_process	The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
GO:0051264	mono-olein transacylation activity	molecular_function	Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.
GO:0051265	diolein transacylation activity	molecular_function	Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.
GO:0051266	sirohydrochlorin ferrochelatase activity	molecular_function	Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.
GO:0051267	CP2 mannose-ethanolamine phosphotransferase activity	molecular_function	Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.
GO:0051268	alpha-keto amide reductase activity	molecular_function	Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.
GO:0051269	alpha-keto ester reductase activity	molecular_function	Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.
GO:0051273	beta-glucan metabolic process	biological_process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.
GO:0051274	beta-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-glucans.
GO:0051275	beta-glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-glucans.
GO:0051276	chromosome organization	biological_process	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0051278	fungal-type cell wall polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.
GO:0051279	regulation of release of sequestered calcium ion into cytosol	biological_process	Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	biological_process	Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
GO:0051282	regulation of sequestering of calcium ion	biological_process	Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
GO:0051283	negative regulation of sequestering of calcium ion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
GO:0051284	positive regulation of sequestering of calcium ion	biological_process	Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
GO:0051285	cell cortex of cell tip	cellular_component	The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
GO:0051286	cell tip	cellular_component	The region at the end of the longest axis of a cylindrical or elongated cell.
GO:0051287	NAD binding	molecular_function	Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
GO:0051289	protein homotetramerization	biological_process	The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
GO:0051290	protein heterotetramerization	biological_process	The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
GO:0051291	protein heterooligomerization	biological_process	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO:0051292	nuclear pore complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.
GO:0051293	establishment of spindle localization	biological_process	The directed movement of the spindle to a specific location in the cell.
GO:0051294	establishment of spindle orientation	biological_process	Any process that set the alignment of spindle relative to other cellular structures.
GO:0051295	establishment of meiotic spindle localization	biological_process	The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.
GO:0051296	establishment of meiotic spindle orientation	biological_process	Any process that set the alignment of meiotic spindle relative to other cellular structures.
GO:0051298	centrosome duplication	biological_process	The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
GO:0051299	centrosome separation	biological_process	The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
GO:0051300	spindle pole body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.
GO:0051301	cell division	biological_process	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
GO:0051302	regulation of cell division	biological_process	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
GO:0051303	establishment of chromosome localization	biological_process	The directed movement of a chromosome to a specific location.
GO:0051304	chromosome separation	biological_process	The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
GO:0051305	chromosome movement towards spindle pole	biological_process	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.
GO:0051306	mitotic sister chromatid separation	biological_process	The process in which sister chromatids are physically detached from each other during mitosis.
GO:0051307	meiotic chromosome separation	biological_process	The process in which chromosomes are physically detached from each other during meiosis.
GO:0051308	male meiosis chromosome separation	biological_process	The process in which paired chromosomes are physically detached from each other during male meiosis.
GO:0051309	female meiosis chromosome separation	biological_process	The process in which paired chromosomes are physically detached from each other during female meiosis.
GO:0051310	metaphase chromosome alignment	biological_process	A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
GO:0051311	meiotic metaphase chromosome alignment	biological_process	A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
GO:0051315	attachment of mitotic spindle microtubules to kinetochore	biological_process	The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.
GO:0051316	attachment of meiotic spindle microtubules to kinetochore	biological_process	The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis.
GO:0051318	G1 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
GO:0051319	G2 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
GO:0051320	S phase	biological_process	The cell cycle phase, following G1, during which DNA synthesis takes place.
GO:0051321	meiotic cell cycle	biological_process	Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
GO:0051322	anaphase	biological_process	The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
GO:0051323	metaphase	biological_process	The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
GO:0051324	prophase	biological_process	The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
GO:0051325	interphase	biological_process	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
GO:0051326	telophase	biological_process	The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
GO:0051327	meiotic M phase	biological_process	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
GO:0051328	meiotic interphase	biological_process	The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
GO:0051329	mitotic interphase	biological_process	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
GO:0051330	meiotic G1 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.
GO:0051331	meiotic G2 phase	biological_process	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.
GO:0051332	meiotic S phase	biological_process	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.
GO:0051333	meiotic nuclear membrane reassembly	biological_process	The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.
GO:0051334	meiosis I nuclear membrane reassembly	biological_process	The reformation of the nuclear membranes during meiosis I.
GO:0051335	meiosis II nuclear membrane reassembly	biological_process	The reformation of the nuclear membrane during meiosis II.
GO:0051336	regulation of hydrolase activity	biological_process	Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0051337	amitosis	biological_process	Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.
GO:0051338	regulation of transferase activity	biological_process	Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0051339	regulation of lyase activity	biological_process	Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0051340	regulation of ligase activity	biological_process	Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
GO:0051341	regulation of oxidoreductase activity	biological_process	Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	biological_process	Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	biological_process	Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
GO:0051345	positive regulation of hydrolase activity	biological_process	Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GO:0051346	negative regulation of hydrolase activity	biological_process	Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GO:0051347	positive regulation of transferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GO:0051348	negative regulation of transferase activity	biological_process	Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GO:0051349	positive regulation of lyase activity	biological_process	Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0051350	negative regulation of lyase activity	biological_process	Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0051351	positive regulation of ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GO:0051352	negative regulation of ligase activity	biological_process	Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GO:0051353	positive regulation of oxidoreductase activity	biological_process	Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GO:0051354	negative regulation of oxidoreductase activity	biological_process	Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GO:0051355	proprioception involved in equilibrioception	biological_process	The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
GO:0051356	visual perception involved in equilibrioception	biological_process	The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
GO:0051363	peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein	biological_process	The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
GO:0051364	N-terminal peptidyl-proline N-formylation	biological_process	The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.
GO:0051365	cellular response to potassium ion starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.
GO:0051366	protein decanoylation	biological_process	The modification of a protein amino acid by formation of an ester or amide with decanoic acid.
GO:0051367	peptidyl-serine decanoylation	biological_process	The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.
GO:0051368	peptidyl-threonine octanoylation	biological_process	The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.
GO:0051369	peptidyl-threonine decanoylation	biological_process	The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.
GO:0051371	muscle alpha-actinin binding	molecular_function	Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
GO:0051373	FATZ binding	molecular_function	Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.
GO:0051377	mannose-ethanolamine phosphotransferase activity	molecular_function	Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.
GO:0051378	serotonin binding	molecular_function	Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
GO:0051379	epinephrine binding	molecular_function	Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
GO:0051380	norepinephrine binding	molecular_function	Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
GO:0051381	histamine binding	molecular_function	Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0051382	kinetochore assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
GO:0051383	kinetochore organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
GO:0051384	response to glucocorticoid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
GO:0051385	response to mineralocorticoid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
GO:0051391	tRNA acetylation	biological_process	The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0051392	tRNA N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.
GO:0051393	alpha-actinin binding	molecular_function	Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
GO:0051394	regulation of nerve growth factor receptor activity	biological_process	Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
GO:0051395	negative regulation of nerve growth factor receptor activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
GO:0051396	positive regulation of nerve growth factor receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
GO:0051400	BH domain binding	molecular_function	Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.
GO:0051401	CH domain binding	molecular_function	Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.
GO:0051402	neuron apoptotic process	biological_process	Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
GO:0051403	stress-activated MAPK cascade	biological_process	The series of molecular signals in which a stress-activated MAP kinase cascade relays a signal; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.
GO:0051407	glycerone phosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).
GO:0051408	glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).
GO:0051409	response to nitrosative stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
GO:0051410	detoxification of nitrogen compound	biological_process	Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
GO:0051412	response to corticosterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
GO:0051413	response to cortisone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.
GO:0051414	response to cortisol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
GO:0051415	microtubule nucleation by interphase microtubule organizing center	biological_process	The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.
GO:0051417	microtubule nucleation by spindle pole body	biological_process	The 'de novo' formation of a microtubule, mediated by the spindle pole body.
GO:0051418	microtubule nucleation by microtubule organizing center	biological_process	The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.
GO:0051424	corticotropin-releasing hormone binding	molecular_function	Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
GO:0051425	PTB domain binding	molecular_function	Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain.
GO:0051427	hormone receptor binding	molecular_function	Binding to a receptor for a hormone.
GO:0051428	peptide hormone receptor binding	molecular_function	Binding to a receptor for a peptide hormone.
GO:0051429	corticotropin-releasing hormone receptor binding	molecular_function	Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
GO:0051430	corticotropin-releasing hormone receptor 1 binding	molecular_function	Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.
GO:0051431	corticotropin-releasing hormone receptor 2 binding	molecular_function	Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.
GO:0051432	BH1 domain binding	molecular_function	Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
GO:0051433	BH2 domain binding	molecular_function	Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
GO:0051434	BH3 domain binding	molecular_function	Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.
GO:0051435	BH4 domain binding	molecular_function	Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.
GO:0051438	regulation of ubiquitin-protein transferase activity	biological_process	Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.
GO:0051443	positive regulation of ubiquitin-protein transferase activity	biological_process	Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
GO:0051444	negative regulation of ubiquitin-protein transferase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
GO:0051445	regulation of meiotic cell cycle	biological_process	Any process that modulates the rate or extent of progression through the meiotic cell cycle.
GO:0051446	positive regulation of meiotic cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
GO:0051447	negative regulation of meiotic cell cycle	biological_process	Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
GO:0051448	gonadotropin-releasing hormone binding	molecular_function	Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
GO:0051449	thyrotropin-releasing hormone binding	molecular_function	Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.
GO:0051450	myoblast proliferation	biological_process	The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0051451	myoblast migration	biological_process	The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
GO:0051452	intracellular pH reduction	biological_process	Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.
GO:0051453	regulation of intracellular pH	biological_process	Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
GO:0051454	intracellular pH elevation	biological_process	Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
GO:0051455	spindle attachment to meiosis I kinetochore	biological_process	The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.
GO:0051456	attachment of meiotic spindle microtubules to meiosis II kinetochore	biological_process	The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.
GO:0051457	maintenance of protein location in nucleus	biological_process	Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.
GO:0051458	corticotropin secretion	biological_process	The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.
GO:0051459	regulation of corticotropin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
GO:0051460	negative regulation of corticotropin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
GO:0051461	positive regulation of corticotropin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.
GO:0051462	regulation of cortisol secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.
GO:0051463	negative regulation of cortisol secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.
GO:0051464	positive regulation of cortisol secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.
GO:0051465	negative regulation of corticotropin-releasing hormone secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.
GO:0051467	detection of steroid hormone stimulus	biological_process	The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.
GO:0051468	detection of glucocorticoid hormone stimulus	biological_process	The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
GO:0051469	vesicle fusion with vacuole	biological_process	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.
GO:0051470	ectoine transport	biological_process	The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
GO:0051472	glucosylglycerol metabolic process	biological_process	The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
GO:0051473	glucosylglycerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
GO:0051474	glucosylglycerol transmembrane transporter activity	molecular_function	Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
GO:0051475	glucosylglycerol transmembrane transport	biological_process	The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane.
GO:0051476	phosphoenolpyruvate-dependent mannosylglycerate phosphotransferase system	biological_process	A phosphoenolpyruvate-dependent sugar phosphotransferase transport specific for mammosylglycerate.
GO:0051477	mannosylglycerate transmembrane transporter activity	molecular_function	Enables the transfer of a mannosylglycerate from one side of a membrane to the other.
GO:0051478	mannosylglycerate metabolic process	biological_process	The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.
GO:0051479	mannosylglycerate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.
GO:0051480	regulation of cytosolic calcium ion concentration	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
GO:0051481	negative regulation of cytosolic calcium ion concentration	biological_process	Any process that decreases the concentration of calcium ions in the cytosol.
GO:0051483	terpenoid biosynthetic process, mevalonate-independent	biological_process	The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.
GO:0051484	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
GO:0051485	terpenoid biosynthetic process, mevalonate-dependent	biological_process	The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.
GO:0051486	isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.
GO:0051489	regulation of filopodium assembly	biological_process	Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
GO:0051490	negative regulation of filopodium assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
GO:0051491	positive regulation of filopodium assembly	biological_process	Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
GO:0051492	regulation of stress fiber assembly	biological_process	Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
GO:0051493	regulation of cytoskeleton organization	biological_process	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0051494	negative regulation of cytoskeleton organization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0051495	positive regulation of cytoskeleton organization	biological_process	Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0051496	positive regulation of stress fiber assembly	biological_process	Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
GO:0051497	negative regulation of stress fiber assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
GO:0051498	syn-copalyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.
GO:0051499	D-aminoacyl-tRNA deacylase activity	molecular_function	Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA.
GO:0051500	D-tyrosyl-tRNA(Tyr) deacylase activity	molecular_function	Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA.
GO:0051501	diterpene phytoalexin metabolic process	biological_process	The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.
GO:0051502	diterpene phytoalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.
GO:0051503	adenine nucleotide transport	biological_process	The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051504	diterpene phytoalexin precursor biosynthetic process pathway	biological_process	A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.
GO:0051506	ergosterol UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol.
GO:0051507	beta-sitosterol UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol.
GO:0051508	stigmasterol UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol.
GO:0051509	tomatidine UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine.
GO:0051510	regulation of unidimensional cell growth	biological_process	Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
GO:0051511	negative regulation of unidimensional cell growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
GO:0051512	positive regulation of unidimensional cell growth	biological_process	Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
GO:0051513	regulation of monopolar cell growth	biological_process	Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
GO:0051514	negative regulation of monopolar cell growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
GO:0051515	positive regulation of monopolar cell growth	biological_process	Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
GO:0051516	regulation of bipolar cell growth	biological_process	Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
GO:0051517	negative regulation of bipolar cell growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
GO:0051518	positive regulation of bipolar cell growth	biological_process	Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
GO:0051519	activation of bipolar cell growth	biological_process	Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.
GO:0051520	termination of bipolar cell growth	biological_process	Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.
GO:0051521	termination of monopolar cell growth	biological_process	Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.
GO:0051522	activation of monopolar cell growth	biological_process	Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.
GO:0051523	cell growth mode switching, monopolar to bipolar	biological_process	The process in which a cell switches from monopolar cell growth to bipolar cell growth.
GO:0051524	cell growth mode switching, bipolar to monopolar	biological_process	The process in which a cell switches from bipolar cell growth to monopolar cell growth.
GO:0051525	NFAT protein binding	molecular_function	Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
GO:0051536	iron-sulfur cluster binding	molecular_function	Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.
GO:0051537	2 iron, 2 sulfur cluster binding	molecular_function	Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
GO:0051538	3 iron, 4 sulfur cluster binding	molecular_function	Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
GO:0051539	4 iron, 4 sulfur cluster binding	molecular_function	Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
GO:0051540	metal cluster binding	molecular_function	Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.
GO:0051541	elastin metabolic process	biological_process	The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
GO:0051542	elastin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
GO:0051543	regulation of elastin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
GO:0051544	positive regulation of elastin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
GO:0051545	negative regulation of elastin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
GO:0051546	keratinocyte migration	biological_process	The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.
GO:0051547	regulation of keratinocyte migration	biological_process	Any process that modulates the frequency, rate or extent of keratinocyte migration.
GO:0051548	negative regulation of keratinocyte migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.
GO:0051549	positive regulation of keratinocyte migration	biological_process	Any process that activates or increases the frequency, rate or extent of keratinocyte migration.
GO:0051550	aurone metabolic process	biological_process	The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.
GO:0051551	aurone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.
GO:0051552	flavone metabolic process	biological_process	The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
GO:0051553	flavone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
GO:0051554	flavonol metabolic process	biological_process	The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
GO:0051555	flavonol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
GO:0051556	leucoanthocyanidin metabolic process	biological_process	The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
GO:0051557	leucoanthocyanidin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
GO:0051558	phlobaphene metabolic process	biological_process	The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
GO:0051559	phlobaphene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
GO:0051560	mitochondrial calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
GO:0051561	positive regulation of mitochondrial calcium ion concentration	biological_process	Any process that increases the concentration of calcium ions in mitochondria.
GO:0051562	negative regulation of mitochondrial calcium ion concentration	biological_process	Any process that decreases the concentration of calcium ions in mitochondria.
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.
GO:0051564	positive regulation of smooth endoplasmic reticulum calcium ion concentration	biological_process	Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.
GO:0051565	negative regulation of smooth endoplasmic reticulum calcium ion concentration	biological_process	Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.
GO:0051566	anthocyanidin-3-glucoside rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.
GO:0051567	histone H3-K9 methylation	biological_process	The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
GO:0051568	histone H3-K4 methylation	biological_process	The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
GO:0051569	regulation of histone H3-K4 methylation	biological_process	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
GO:0051570	regulation of histone H3-K9 methylation	biological_process	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
GO:0051571	positive regulation of histone H3-K4 methylation	biological_process	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
GO:0051572	negative regulation of histone H3-K4 methylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
GO:0051573	negative regulation of histone H3-K9 methylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
GO:0051574	positive regulation of histone H3-K9 methylation	biological_process	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	molecular_function	Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.
GO:0051580	regulation of neurotransmitter uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
GO:0051581	negative regulation of neurotransmitter uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
GO:0051582	positive regulation of neurotransmitter uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
GO:0051583	dopamine uptake involved in synaptic transmission	biological_process	The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0051584	regulation of dopamine uptake involved in synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.
GO:0051585	negative regulation of dopamine uptake involved in synaptic transmission	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.
GO:0051586	positive regulation of dopamine uptake involved in synaptic transmission	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.
GO:0051587	inhibition of dopamine uptake involved in synaptic transmission	biological_process	Any process that prevents the activation of the directed movement of dopamine into a cell.
GO:0051588	regulation of neurotransmitter transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051589	negative regulation of neurotransmitter transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051590	positive regulation of neurotransmitter transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051591	response to cAMP	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
GO:0051592	response to calcium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
GO:0051593	response to folic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
GO:0051594	detection of glucose	biological_process	The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.
GO:0051595	response to methylglyoxal	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
GO:0051596	methylglyoxal catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
GO:0051597	response to methylmercury	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
GO:0051598	meiotic recombination checkpoint signaling	biological_process	A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
GO:0051599	response to hydrostatic pressure	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
GO:0051600	regulation of endocytosis by exocyst localization	biological_process	Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
GO:0051601	exocyst localization	biological_process	Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
GO:0051602	response to electrical stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
GO:0051603	proteolysis involved in protein catabolic process	biological_process	The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
GO:0051604	protein maturation	biological_process	Any process leading to the attainment of the full functional capacity of a protein.
GO:0051606	detection of stimulus	biological_process	The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
GO:0051607	defense response to virus	biological_process	Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
GO:0051608	histamine transport	biological_process	The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0051609	inhibition of neurotransmitter uptake	biological_process	Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.
GO:0051610	serotonin uptake	biological_process	The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
GO:0051611	regulation of serotonin uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.
GO:0051612	negative regulation of serotonin uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.
GO:0051613	positive regulation of serotonin uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.
GO:0051614	inhibition of serotonin uptake	biological_process	Any process that prevents the activation of the directed movement of serotonin into a cell.
GO:0051615	histamine uptake	biological_process	The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
GO:0051616	regulation of histamine uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.
GO:0051617	negative regulation of histamine uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.
GO:0051618	positive regulation of histamine uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.
GO:0051619	inhibition of histamine uptake	biological_process	Any process that prevents the activation of the directed movement of histamine into a cell.
GO:0051620	norepinephrine uptake	biological_process	The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
GO:0051621	regulation of norepinephrine uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.
GO:0051622	negative regulation of norepinephrine uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.
GO:0051623	positive regulation of norepinephrine uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.
GO:0051624	inhibition of norepinephrine uptake	biological_process	Any process that prevents the activation of the directed movement of norepinephrine into a cell.
GO:0051625	epinephrine uptake	biological_process	The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
GO:0051626	regulation of epinephrine uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.
GO:0051627	negative regulation of epinephrine uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.
GO:0051628	positive regulation of epinephrine uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.
GO:0051629	inhibition of epinephrine uptake	biological_process	Any process that prevents the activation of the directed movement of epinephrine into a cell.
GO:0051630	acetylcholine uptake	biological_process	The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
GO:0051631	regulation of acetylcholine uptake	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.
GO:0051632	negative regulation of acetylcholine uptake	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.
GO:0051633	positive regulation of acetylcholine uptake	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.
GO:0051634	inhibition of acetylcholine uptake	biological_process	Any process that prevents the activation of the directed movement of acetylcholine into a cell.
GO:0051638	barbed-end actin filament uncapping	biological_process	The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
GO:0051639	actin filament network formation	biological_process	The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
GO:0051640	organelle localization	biological_process	Any process in which an organelle is transported to, and/or maintained in, a specific location.
GO:0051641	cellular localization	biological_process	A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0051642	centrosome localization	biological_process	Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
GO:0051643	endoplasmic reticulum localization	biological_process	Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.
GO:0051644	plastid localization	biological_process	Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.
GO:0051645	Golgi localization	biological_process	Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
GO:0051646	mitochondrion localization	biological_process	Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
GO:0051647	nucleus localization	biological_process	Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
GO:0051648	vesicle localization	biological_process	Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
GO:0051649	establishment of localization in cell	biological_process	Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051650	establishment of vesicle localization	biological_process	The directed movement of a vesicle to a specific location.
GO:0051651	maintenance of location in cell	biological_process	Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
GO:0051652	maintenance of chromosome location	biological_process	Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051653	spindle localization	biological_process	Any process in which is the spindle is transported to, and/or maintained in, a specific location.
GO:0051654	establishment of mitochondrion localization	biological_process	The directed movement of the mitochondrion to a specific location.
GO:0051655	maintenance of vesicle location	biological_process	Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051656	establishment of organelle localization	biological_process	The directed movement of an organelle to a specific location.
GO:0051657	maintenance of organelle location	biological_process	Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051658	maintenance of nucleus location	biological_process	Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051659	maintenance of mitochondrion location	biological_process	Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051660	establishment of centrosome localization	biological_process	The directed movement of the centrosome to a specific location.
GO:0051661	maintenance of centrosome location	biological_process	Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification	biological_process	The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.
GO:0051664	nuclear pore localization	biological_process	Any process in which nuclear pores are transported to, or maintained in, a specific location.
GO:0051665	membrane raft localization	biological_process	Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
GO:0051666	actin cortical patch localization	biological_process	Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
GO:0051667	establishment of plastid localization	biological_process	The directed movement of a plastid to a specific location in the cell.
GO:0051668	localization within membrane	biological_process	Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
GO:0051669	fructan beta-fructosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.
GO:0051670	inulinase activity	molecular_function	Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.
GO:0051673	disruption of plasma membrane integrity in another organism	biological_process	The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane.
GO:0051674	localization of cell	biological_process	Any process in which a cell is transported to, and/or maintained in, a specific location.
GO:0051675	isopullulanase activity	molecular_function	Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).
GO:0051676	pullulan metabolic process	biological_process	The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
GO:0051677	pullulan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
GO:0051678	pullulan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
GO:0051679	6-alpha-maltosylglucose metabolic process	biological_process	The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.
GO:0051680	6-alpha-maltosylglucose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.
GO:0051681	6-alpha-maltosylglucose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.
GO:0051682	galactomannan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.
GO:0051683	establishment of Golgi localization	biological_process	The directed movement of the Golgi to a specific location.
GO:0051684	maintenance of Golgi location	biological_process	Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051685	maintenance of ER location	biological_process	Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051686	establishment of ER localization	biological_process	The directed movement of the endoplasmic reticulum to a specific location.
GO:0051687	maintenance of spindle location	biological_process	Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051688	maintenance of plastid location	biological_process	Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.
GO:0051693	actin filament capping	biological_process	The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
GO:0051694	pointed-end actin filament capping	biological_process	The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
GO:0051695	actin filament uncapping	biological_process	The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
GO:0051696	pointed-end actin filament uncapping	biological_process	The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
GO:0051697	protein delipidation	biological_process	The breakage of covalent bonds to detach lipid groups from a protein.
GO:0051698	saccharopine oxidase activity	molecular_function	Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.
GO:0051700	fructosyl-amino acid oxidase activity	molecular_function	Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.
GO:0051701	biological process involved in interaction with host	biological_process	An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
GO:0051702	biological process involved in interaction with symbiont	biological_process	An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
GO:0051703	biological process involved in intraspecies interaction between organisms	biological_process	Any process in which an organism has an effect on an organism of the same species.
GO:0051707	response to other organism	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
GO:0051709	regulation of killing of cells of another organism	biological_process	Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.
GO:0051711	negative regulation of killing of cells of another organism	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.
GO:0051712	positive regulation of killing of cells of another organism	biological_process	Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.
GO:0051715	cytolysis in another organism	biological_process	The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.
GO:0051716	cellular response to stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
GO:0051718	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).
GO:0051719	DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.
GO:0051720	DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.
GO:0051721	protein phosphatase 2A binding	molecular_function	Binding to protein phosphatase 2A.
GO:0051722	protein C-terminal methylesterase activity	molecular_function	Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.
GO:0051723	protein methylesterase activity	molecular_function	Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.
GO:0051724	NAD transmembrane transporter activity	molecular_function	Enables the transfer of NAD from one side of a membrane to the other.
GO:0051725	protein de-ADP-ribosylation	biological_process	The process of removing one or more ADP-ribose residues from a protein.
GO:0051726	regulation of cell cycle	biological_process	Any process that modulates the rate or extent of progression through the cell cycle.
GO:0051728	cell cycle switching, mitotic to meiotic cell cycle	biological_process	The process in which a cell switches cell cycle mode from mitotic to meiotic division.
GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle	biological_process	The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.
GO:0051730	GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.
GO:0051731	polynucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
GO:0051734	ATP-dependent polynucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
GO:0051735	GTP-dependent polynucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
GO:0051736	ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.
GO:0051737	GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	molecular_function	Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.
GO:0051738	xanthophyll binding	molecular_function	Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.
GO:0051740	ethylene binding	molecular_function	Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
GO:0051741	2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.
GO:0051742	2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.
GO:0051743	red chlorophyll catabolite reductase activity	molecular_function	Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.
GO:0051744	3,8-divinyl protochlorophyllide a 8-vinyl reductase activity	molecular_function	Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.
GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	molecular_function	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
GO:0051746	thalianol synthase activity	molecular_function	Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).
GO:0051747	cytosine C-5 DNA demethylase activity	molecular_function	Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.
GO:0051748	UTP-monosaccharide-1-phosphate uridylyltransferase activity	molecular_function	Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.
GO:0051749	indole acetic acid carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.
GO:0051750	delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity	molecular_function	Catalysis of the reaction: a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.
GO:0051751	alpha-1,4-mannosyltransferase activity	molecular_function	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.
GO:0051752	phosphoglucan, water dikinase activity	molecular_function	Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate.
GO:0051753	mannan synthase activity	molecular_function	Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.
GO:0051754	meiotic sister chromatid cohesion, centromeric	biological_process	The cell cycle process in which centromeres of sister chromatids are joined during meiosis.
GO:0051755	meiotic sister chromatid arm separation	biological_process	The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
GO:0051756	meiotic sister chromatid centromere separation	biological_process	The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.
GO:0051757	meiotic sister chromatid separation	biological_process	The process in which sister chromatids are physically detached from each other during meiosis.
GO:0051758	homologous chromosome movement towards spindle pole in meiosis I anaphase	biological_process	The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.
GO:0051759	sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation	biological_process	The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.
GO:0051760	meiotic sister chromatid cohesion, arms	biological_process	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis.
GO:0051761	sesquiterpene metabolic process	biological_process	The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
GO:0051762	sesquiterpene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
GO:0051763	sesquiterpene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
GO:0051764	actin crosslink formation	biological_process	The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
GO:0051765	inositol tetrakisphosphate kinase activity	molecular_function	Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.
GO:0051766	inositol trisphosphate kinase activity	molecular_function	Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP.
GO:0051767	nitric-oxide synthase biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.
GO:0051775	response to redox state	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
GO:0051776	detection of redox state	biological_process	The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
GO:0051777	ent-kaurenoate oxidase activity	molecular_function	Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
GO:0051778	ent-7-alpha-hydroxykaurenoate oxidase activity	molecular_function	Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
GO:0051779	gibberellin 12-aldehyde oxidase activity	molecular_function	Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
GO:0051780	behavioral response to nutrient	biological_process	Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.
GO:0051781	positive regulation of cell division	biological_process	Any process that activates or increases the frequency, rate or extent of cell division.
GO:0051782	negative regulation of cell division	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
GO:0051783	regulation of nuclear division	biological_process	Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GO:0051784	negative regulation of nuclear division	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GO:0051785	positive regulation of nuclear division	biological_process	Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GO:0051786	all-trans-retinol 13,14-reductase activity	molecular_function	Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.
GO:0051787	misfolded protein binding	molecular_function	Binding to a misfolded protein.
GO:0051788	response to misfolded protein	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
GO:0051790	short-chain fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons.
GO:0051791	medium-chain fatty acid metabolic process	biological_process	The chemical reactions and pathways involving a medium-chain fatty acid, a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0051792	medium-chain fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0051793	medium-chain fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0051794	regulation of timing of catagen	biological_process	Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
GO:0051795	positive regulation of timing of catagen	biological_process	Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
GO:0051796	negative regulation of timing of catagen	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
GO:0051797	regulation of hair follicle development	biological_process	Any process that modulates the frequency, rate or extent of hair follicle development.
GO:0051798	positive regulation of hair follicle development	biological_process	Any process that activates or increases the frequency, rate or extent of hair follicle development.
GO:0051799	negative regulation of hair follicle development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.
GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
GO:0051819	induction by symbiont of tumor or growth in host	biological_process	The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.
GO:0051823	regulation of synapse structural plasticity	biological_process	Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.
GO:0051826	negative regulation of synapse structural plasticity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.
GO:0051835	positive regulation of synapse structural plasticity	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.
GO:0051838	cytolysis by host of symbiont cells	biological_process	The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051844	translocation of peptides or proteins into symbiont	biological_process	The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051850	acquisition of nutrients from symbiont	biological_process	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051851	modulation by host of symbiont process	biological_process	The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051861	glycolipid binding	molecular_function	Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.
GO:0051862	translocation of molecules into symbiont	biological_process	The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051864	histone H3K36 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0051865	protein autoubiquitination	biological_process	The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
GO:0051866	general adaptation syndrome	biological_process	General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.
GO:0051867	general adaptation syndrome, behavioral process	biological_process	The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.
GO:0051870	methotrexate binding	molecular_function	Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
GO:0051871	dihydrofolic acid binding	molecular_function	Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.
GO:0051872	sphingosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
GO:0051873	killing by host of symbiont cells	biological_process	Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0051874	sphinganine-1-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
GO:0051875	pigment granule localization	biological_process	Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.
GO:0051876	pigment granule dispersal	biological_process	The directed movement of pigment granules within a cell towards the cell periphery.
GO:0051877	pigment granule aggregation in cell center	biological_process	The directed movement of dispersed pigment granules towards the center of the cell.
GO:0051878	lateral element assembly	biological_process	The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements.
GO:0051879	Hsp90 protein binding	molecular_function	Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
GO:0051880	G-quadruplex DNA binding	molecular_function	Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
GO:0051881	regulation of mitochondrial membrane potential	biological_process	Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0051882	mitochondrial depolarization	biological_process	The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
GO:0051884	regulation of timing of anagen	biological_process	Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.
GO:0051885	positive regulation of timing of anagen	biological_process	Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.
GO:0051886	negative regulation of timing of anagen	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.
GO:0051887	regulation of timing of exogen	biological_process	Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.
GO:0051888	positive regulation of timing of exogen	biological_process	Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.
GO:0051889	negative regulation of timing of exogen	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.
GO:0051890	regulation of cardioblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0051891	positive regulation of cardioblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0051892	negative regulation of cardioblast differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0051893	regulation of focal adhesion assembly	biological_process	Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.
GO:0051894	positive regulation of focal adhesion assembly	biological_process	Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
GO:0051895	negative regulation of focal adhesion assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
GO:0051898	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
GO:0051899	membrane depolarization	biological_process	The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0051900	regulation of mitochondrial depolarization	biological_process	Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
GO:0051901	positive regulation of mitochondrial depolarization	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
GO:0051902	negative regulation of mitochondrial depolarization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	molecular_function	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
GO:0051904	pigment granule transport	biological_process	The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051905	establishment of pigment granule localization	biological_process	The directed movement of a pigment granule to a specific location.
GO:0051906	maintenance of pigment granule location	biological_process	Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.
GO:0051907	S-(hydroxymethyl)glutathione synthase activity	molecular_function	Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione.
GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	molecular_function	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.
GO:0051909	acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate	molecular_function	Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O.
GO:0051911	Methanosarcina-phenazine hydrogenase activity	molecular_function	Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine.
GO:0051912	CoB--CoM heterodisulfide reductase activity	molecular_function	Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.
GO:0051913	regulation of synaptic plasticity by chemical substance	biological_process	The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require.
GO:0051914	positive regulation of synaptic plasticity by chemical substance	biological_process	The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.
GO:0051915	induction of synaptic plasticity by chemical substance	biological_process	The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.
GO:0051916	granulocyte colony-stimulating factor binding	molecular_function	Binding to granulocyte colony-stimulating factor, G-CSF.
GO:0051917	regulation of fibrinolysis	biological_process	Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
GO:0051918	negative regulation of fibrinolysis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
GO:0051919	positive regulation of fibrinolysis	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
GO:0051920	peroxiredoxin activity	molecular_function	Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.
GO:0051921	adenosylcobyric acid synthase (glutamine-hydrolyzing) activity	molecular_function	Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H+ + 4 phosphate.
GO:0051922	cholesterol sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate + H+.
GO:0051923	sulfation	biological_process	The addition of a sulfate group to a molecule.
GO:0051924	regulation of calcium ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051926	negative regulation of calcium ion transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051928	positive regulation of calcium ion transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051930	regulation of sensory perception of pain	biological_process	Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GO:0051931	regulation of sensory perception	biological_process	Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GO:0051932	synaptic transmission, GABAergic	biological_process	The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0051933	amino acid neurotransmitter reuptake	biological_process	The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
GO:0051934	catecholamine uptake involved in synaptic transmission	biological_process	The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
GO:0051935	glutamate reuptake	biological_process	The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
GO:0051936	gamma-aminobutyric acid reuptake	biological_process	The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
GO:0051937	catecholamine transport	biological_process	The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
GO:0051938	L-glutamate import	biological_process	The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.
GO:0051939	gamma-aminobutyric acid import	biological_process	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.
GO:0051940	regulation of catecholamine uptake involved in synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
GO:0051941	regulation of amino acid uptake involved in synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
GO:0051942	negative regulation of amino acid uptake involved in synaptic transmission	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
GO:0051943	positive regulation of amino acid uptake involved in synaptic transmission	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
GO:0051946	regulation of glutamate uptake involved in transmission of nerve impulse	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
GO:0051947	regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
GO:0051948	negative regulation of glutamate uptake involved in transmission of nerve impulse	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
GO:0051949	negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
GO:0051950	positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
GO:0051951	positive regulation of glutamate uptake involved in transmission of nerve impulse	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
GO:0051952	regulation of amine transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051953	negative regulation of amine transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051954	positive regulation of amine transport	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051955	regulation of amino acid transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051956	negative regulation of amino acid transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051957	positive regulation of amino acid transport	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0051958	methotrexate transport	biological_process	The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
GO:0051959	dynein light intermediate chain binding	molecular_function	Binding to a light intermediate chain of the dynein complex.
GO:0051960	regulation of nervous system development	biological_process	Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GO:0051961	negative regulation of nervous system development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GO:0051962	positive regulation of nervous system development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GO:0051963	regulation of synapse assembly	biological_process	Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
GO:0051964	negative regulation of synapse assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
GO:0051965	positive regulation of synapse assembly	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
GO:0051966	regulation of synaptic transmission, glutamatergic	biological_process	Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
GO:0051967	negative regulation of synaptic transmission, glutamatergic	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
GO:0051968	positive regulation of synaptic transmission, glutamatergic	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
GO:0051969	regulation of transmission of nerve impulse	biological_process	Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
GO:0051970	negative regulation of transmission of nerve impulse	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
GO:0051971	positive regulation of transmission of nerve impulse	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
GO:0051972	regulation of telomerase activity	biological_process	Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
GO:0051973	positive regulation of telomerase activity	biological_process	Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
GO:0051974	negative regulation of telomerase activity	biological_process	Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
GO:0051975	lysine biosynthetic process via alpha-aminoadipate and saccharopine	biological_process	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.
GO:0051976	lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate	biological_process	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.
GO:0051977	lysophospholipid transport	biological_process	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
GO:0051978	lysophospholipid:sodium symporter activity	molecular_function	Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
GO:0051979	alginic acid acetylation	biological_process	The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.
GO:0051980	iron-nicotianamine transmembrane transporter activity	molecular_function	Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other.
GO:0051981	copper chelate transmembrane transporter activity	molecular_function	Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
GO:0051982	copper-nicotianamine transmembrane transporter activity	molecular_function	Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.
GO:0051983	regulation of chromosome segregation	biological_process	Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GO:0051984	positive regulation of chromosome segregation	biological_process	Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GO:0051985	negative regulation of chromosome segregation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GO:0051986	negative regulation of attachment of spindle microtubules to kinetochore	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	biological_process	Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
GO:0051989	coproporphyrinogen dehydrogenase activity	molecular_function	Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
GO:0051991	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity	molecular_function	Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.
GO:0051992	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol.
GO:0051993	abscisic acid glucose ester beta-glucosidase activity	molecular_function	Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.
GO:0051994	P-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.
GO:0051995	Se-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.
GO:0051996	squalene synthase activity	molecular_function	Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.
GO:0051997	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity	molecular_function	Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.
GO:0051998	protein carboxyl O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group to a carboxyl group on a protein.
GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
GO:0052001	adhesion to host cell via type IV pili	biological_process	Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052003	symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway	biological_process	A process in which a virus interferes with, inhibits or disrupts a host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052005	suppression by symbiont of host ethylene-mediated defense response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052008	disruption by symbiont of host cellular component	biological_process	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052009	disruption by symbiont of host cell wall	biological_process	A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052019	modulation by symbiont of host hormone or growth regulator levels	biological_process	The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052020	modification by symbiont of host cell wall	biological_process	The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052021	modulation by symbiont of ethylene levels in host	biological_process	The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052022	modulation by symbiont of jasmonic acid levels in host	biological_process	The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052023	modulation by symbiont of salicylic acid levels in host	biological_process	The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052024	positive regulation by symbiont of hormone or growth regulator levels in host	biological_process	The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052025	disruption by symbiont of host cell membrane	biological_process	The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052026	modulation by symbiont of host transcription	biological_process	Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052027	perturbation of host signal transduction pathway	biological_process	A process in which a symbiont alters or subverts a signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052028	symbiont-mediated activation of host signal transduction pathway	biological_process	A process in which a symbiont subverts a signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052029	symbiont-mediated suppression of host signal transduction pathway	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a host signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052031	modulation by symbiont of host defense response	biological_process	Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052032	perturbation by symbiont of host inflammatory response	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052034	effector-mediated suppression of host pattern-triggered immunity	biological_process	A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052036	suppression by symbiont of host inflammatory response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052038	modulation by symbiont of host intracellular transport	biological_process	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052039	perturbation by symbiont of host cytoskeleton	biological_process	The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052040	modulation by symbiont of host programmed cell death	biological_process	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052041	suppression by symbiont of host programmed cell death	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052042	induction by symbiont of host programmed cell death	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052053	negative regulation by symbiont of host catalytic activity	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052055	modulation by symbiont of host molecular function	biological_process	The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052062	induction by symbiont of host phytoalexin production	biological_process	The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052064	induction by symbiont of defense-related host reactive oxygen species production	biological_process	The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052067	disruption of host phagocytosis	biological_process	A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052074	positive regulation by symbiont of host salicylic acid-mediated defense response	biological_process	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052075	induction by symbiont of host jasmonic acid-mediated defense response	biological_process	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052078	symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway	biological_process	A process in which a virus interferes with, inhibits or disrupts a PAMP signaling pathway in its host organism, initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052080	perturbation of host MAPK signal transduction pathway	biological_process	A process in which a symbiont alters or subverts a MAP kinase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052081	perturbation of defense-related host salicylic acid-mediated signal transduction pathway	biological_process	A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052083	suppression by symbiont of host cell-mediated immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052084	modulation by symbiont of host ethylene-mediated defense response	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052085	suppression of host T-cell mediated immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052086	suppression of host B-cell mediated immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052088	symbiont defense to host-produced jasmonic acid	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052089	modulation by symbiont of host salicylic acid-mediated defense response	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052091	modulation of nutrient release by host	biological_process	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052092	positive regulation of nutrient release by host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052093	formation of specialized structure for nutrient acquisition	biological_process	The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052094	formation of haustorium for nutrient acquisition	biological_process	The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052096	formation of syncytium involving giant cell for nutrient acquisition	biological_process	The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052098	formation by host of specialized structure for nutrient acquisition from symbiont	biological_process	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052102	positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052103	induction of host induced systemic resistance	biological_process	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052104	induction by symbiont of host systemic acquired resistance	biological_process	Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052110	occlusion by symbiont of host vascular system	biological_process	The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052111	disruption by symbiont of host anatomical structure	biological_process	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052112	occlusion by symbiont of host xylem	biological_process	The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052128	positive energy taxis	biological_process	The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
GO:0052129	negative energy taxis	biological_process	The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
GO:0052130	negative aerotaxis	biological_process	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.
GO:0052131	positive aerotaxis	biological_process	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.
GO:0052148	modulation by symbiont of host catalytic activity	biological_process	The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052150	modulation by symbiont of host apoptotic process	biological_process	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052151	positive regulation by symbiont of host apoptotic process	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052154	perturbation of host B-cell mediated immune response	biological_process	A process in which an organism effects a change that affects the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052155	perturbation of host cell-mediated immune response	biological_process	A process in which an organism effects a change that affects cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052156	perturbation of host T-cell mediated immune response	biological_process	A process in which an organism effects a change that affects the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052158	modulation by symbiont of host resistance gene-dependent defense response	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052159	perturbation of host induced systemic resistance	biological_process	A process in which an organism effects a change that affects the induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052160	perturbation of host systemic acquired resistance	biological_process	A process in which an organism effects a change that affects systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052162	modulation by symbiont of defense-related host calcium ion flux	biological_process	Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052163	symbiont defense to host-produced nitric oxide	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052164	symbiont defense to host-produced reactive oxygen species	biological_process	A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response.
GO:0052165	symbiont defense to host-produced phytoalexin	biological_process	Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052167	perturbation of host innate immune response	biological_process	A process in which an organism effects a change that affects the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052168	modulation by symbiont of defense-related host calcium-dependent protein kinase pathway	biological_process	Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052170	suppression of host innate immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052173	response to defenses of other organism	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism.
GO:0052183	disruption of symbiont cellular component	biological_process	The process in which a host organism destabilizes a cellular component of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052200	response to host defenses	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052201	response to symbiont defenses	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052314	phytoalexin metabolic process	biological_process	The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.
GO:0052315	phytoalexin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.
GO:0052316	phytoalexin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.
GO:0052317	camalexin metabolic process	biological_process	The chemical reactions and pathways involving camalexin, an indole phytoalexin.
GO:0052318	regulation of phytoalexin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.
GO:0052319	regulation of phytoalexin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
GO:0052320	positive regulation of phytoalexin metabolic process	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.
GO:0052321	negative regulation of phytoalexin metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.
GO:0052322	positive regulation of phytoalexin biosynthetic process	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
GO:0052323	negative regulation of phytoalexin biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
GO:0052324	plant-type cell wall cellulose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
GO:0052325	cell wall pectin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.
GO:0052344	positive regulation by symbiont of host phytoalexin production	biological_process	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052372	modulation by symbiont of entry into host	biological_process	Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.
GO:0052373	suppression of symbiont entry into host	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.
GO:0052381	tRNA dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.
GO:0052386	cell wall thickening	biological_process	A type of cell wall modification in which the cell wall is reinforced and made thicker.
GO:0052390	induction by symbiont of host innate immune response	biological_process	The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052391	induction by symbiont of defense-related host calcium ion flux	biological_process	The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052403	negative regulation by host of symbiont catalytic activity	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052422	modulation by host of symbiont catalytic activity	biological_process	The process in which a host organism effects a change in the enzyme activity of its symbiont organism.
GO:0052460	modulation of nutrient release by symbiont	biological_process	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052472	modulation by host of symbiont transcription	biological_process	Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription.
GO:0052482	defense response by cell wall thickening	biological_process	A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism.
GO:0052489	negative regulation by host of symbiont programmed cell death	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052519	positive regulation of nutrient release by symbiont	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0052541	plant-type cell wall cellulose metabolic process	biological_process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
GO:0052542	defense response by callose deposition	biological_process	Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0052543	callose deposition in cell wall	biological_process	Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0052544	defense response by callose deposition in cell wall	biological_process	Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0052545	callose localization	biological_process	Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0052546	cell wall pectin metabolic process	biological_process	The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.
GO:0052547	regulation of peptidase activity	biological_process	Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GO:0052548	regulation of endopeptidase activity	biological_process	Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GO:0052553	perturbation of host immune response	biological_process	A process in which an organism effects a change that affects the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052559	induction by symbiont of host immune response	biological_process	Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052562	suppression by symbiont of host immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052572	response to host immune response	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0052573	UDP-D-galactose metabolic process	biological_process	The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.
GO:0052574	UDP-galactose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.
GO:0052575	carbohydrate localization	biological_process	Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0052576	carbohydrate storage	biological_process	The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0052577	germacrene-D synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate.
GO:0052578	alpha-farnesene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate.
GO:0052579	(+)-pulegone reductase, (+)-isomenthone as substrate, activity	molecular_function	Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+.
GO:0052580	(+)-pulegone reductase, (-)-menthone as substrate, activity	molecular_function	Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+.
GO:0052581	(-)-isopiperitenone reductase activity	molecular_function	Catalysis of the reaction: (6R)-isoperitenone + H+ + NADPH = (2R,5R)-isopulegone + NADP+.
GO:0052582	(+)-menthofuran synthase activity	molecular_function	Catalysis of the reaction: (R)-pulegone + H+ + NADPH + O2 = (R)-menthofuran + 2 H2O + NADP+.
GO:0052585	oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.
GO:0052586	oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound.
GO:0052587	diacetyl reductase ((R)-acetoin forming) activity	molecular_function	Catalysis of the reaction: (R)-acetoin + NAD+ = diacetyl + H+ + NADH.
GO:0052588	diacetyl reductase ((S)-acetoin forming) activity	molecular_function	Catalysis of the reaction: (S)-acetoin + NAD+ = diacetyl + H+ + NADH.
GO:0052589	malate dehydrogenase (menaquinone) activity	molecular_function	Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.
GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol.
GO:0052591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.
GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity	molecular_function	Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+.
GO:0052594	aminoacetone:oxygen oxidoreductase(deaminating) activity	molecular_function	Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+.
GO:0052595	aliphatic amine oxidase activity	molecular_function	Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+.
GO:0052596	phenethylamine:oxygen oxidoreductase (deaminating) activity	molecular_function	Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+.
GO:0052597	diamine oxidase activity	molecular_function	Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.
GO:0052598	histamine oxidase activity	molecular_function	Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+.
GO:0052599	methylputrescine oxidase activity	molecular_function	Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+.
GO:0052600	propane-1,3-diamine oxidase activity	molecular_function	Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.
GO:0052601	(S)-limonene 1,2-monooxygenase activity	molecular_function	Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.
GO:0052602	4-chloronitrobenzene nitroreductase activity	molecular_function	Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O.
GO:0052603	1-chloro-4-nitrosobenzene nitroreductase activity	molecular_function	Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O.
GO:0052604	delta-tocopherol cyclase activity	molecular_function	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol.
GO:0052605	gamma-tocopherol cyclase activity	molecular_function	Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol.
GO:0052606	chlorophyllide a oxygenase activity	molecular_function	Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O.
GO:0052607	7-hydroxy-chlorophyllide a oxygenase activity	molecular_function	Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O.
GO:0052608	echinenone 3-hydroxylase activity	molecular_function	Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O.
GO:0052609	4-ketotorulene 3-hydroxylase activity	molecular_function	Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.
GO:0052610	beta-cryptoxanthin hydroxylase activity	molecular_function	Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O.
GO:0052611	beta-carotene 3-hydroxylase activity	molecular_function	Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.
GO:0052612	adonirubin 3-hydroxylase activity	molecular_function	Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O.
GO:0052613	canthaxanthin 3-hydroxylase activity	molecular_function	Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.
GO:0052614	uracil oxygenase activity	molecular_function	Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate.
GO:0052615	ent-kaurene oxidase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.
GO:0052616	ent-kaur-16-en-19-ol oxidase activity	molecular_function	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al.
GO:0052617	ent-kaur-16-en-19-al oxidase activity	molecular_function	Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate.
GO:0052618	coenzyme F420-0:L-glutamate ligase activity	molecular_function	Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.
GO:0052619	coenzyme F420-1:gamma-L-glutamate ligase activity	molecular_function	Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.
GO:0052620	thymine dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.
GO:0052621	diguanylate cyclase activity	molecular_function	Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H+.
GO:0052622	ATP dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.
GO:0052623	ADP dimethylallyltransferase activity	molecular_function	Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.
GO:0052624	2-phytyl-1,4-naphthoquinone methyltransferase activity	molecular_function	Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.
GO:0052625	4-aminobenzoate amino acid synthetase activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.
GO:0052626	benzoate amino acid synthetase activity	molecular_function	Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate.
GO:0052627	vanillate amino acid synthetase activity	molecular_function	Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate.
GO:0052628	4-hydroxybenzoate amino acid synthetase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.
GO:0052630	UDP-N-acetylgalactosamine diphosphorylase activity	molecular_function	Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine.
GO:0052631	sphingolipid delta-8 desaturase activity	molecular_function	Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).
GO:0052633	isocitrate hydro-lyase (cis-aconitate-forming) activity	molecular_function	Catalysis of the reaction: cis-aconitate + H2O = isocitrate.
GO:0052634	C-19 gibberellin 2-beta-dioxygenase activity	molecular_function	Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.
GO:0052635	C-20 gibberellin 2-beta-dioxygenase activity	molecular_function	Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.
GO:0052636	arabinosyltransferase activity	molecular_function	Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).
GO:0052637	delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol.
GO:0052638	indole-3-butyrate beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.
GO:0052639	salicylic acid glucosyltransferase (ester-forming) activity	molecular_function	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP.
GO:0052640	salicylic acid glucosyltransferase (glucoside-forming) activity	molecular_function	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.
GO:0052641	benzoic acid glucosyltransferase activity	molecular_function	Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP.
GO:0052642	lysophosphatidic acid phosphatase activity	molecular_function	Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.
GO:0052643	chlorophyllide metabolic process	biological_process	The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl.
GO:0052644	chlorophyllide a metabolic process	biological_process	The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a.
GO:0052645	F420-0 metabolic process	biological_process	The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.
GO:0052646	alditol phosphate metabolic process	biological_process	The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
GO:0052647	pentitol phosphate metabolic process	biological_process	The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.
GO:0052648	ribitol phosphate metabolic process	biological_process	The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
GO:0052649	coenzyme gamma-F420-2 metabolic process	biological_process	The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid.
GO:0052650	NADP-retinol dehydrogenase activity	molecular_function	Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.
GO:0052651	monoacylglycerol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
GO:0052652	cyclic purine nucleotide metabolic process	biological_process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.
GO:0052653	3',5'-cyclic diguanylic acid metabolic process	biological_process	The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.
GO:0052654	L-leucine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.
GO:0052655	L-valine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.
GO:0052656	L-isoleucine transaminase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.
GO:0052657	guanine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.
GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
GO:0052660	R-lactaldehyde reductase activity	molecular_function	Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.
GO:0052661	S-lactaldehyde reductase activity	molecular_function	Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+.
GO:0052662	zeaxanthin epoxidase activity	molecular_function	Catalysis of the reaction: all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].
GO:0052664	nitroalkane oxidase activity	molecular_function	Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2.
GO:0052665	tRNA (uracil-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil.
GO:0052666	tRNA (cytosine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine.
GO:0052667	phosphomethylethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H+.
GO:0052668	CTP:farnesol kinase activity	molecular_function	Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+.
GO:0052670	geraniol kinase activity	molecular_function	Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate.
GO:0052671	geranylgeraniol kinase activity	molecular_function	Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate.
GO:0052672	CTP:geranylgeraniol kinase activity	molecular_function	Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.
GO:0052673	prenol kinase activity	molecular_function	Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.
GO:0052674	ent-pimara-9(11),15-diene synthase activity	molecular_function	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.
GO:0052675	3-methylbutanol:NADP oxidoreductase activity	molecular_function	Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde.
GO:0052676	3-methylbutanol:NAD oxidoreductase activity	molecular_function	Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.
GO:0052677	D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity	molecular_function	Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+.
GO:0052678	levopimaradiene synthase activity	molecular_function	Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.
GO:0052679	terpentetriene synthase activity	molecular_function	Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.
GO:0052680	epi-isozizaene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.
GO:0052681	alpha-bisabolene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate.
GO:0052682	epi-cedrol synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.
GO:0052683	(Z)-gamma-bisabolene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.
GO:0052684	L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity	molecular_function	Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O.
GO:0052685	perillic acid-CoA ligase (ADP-forming) activity	molecular_function	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA.
GO:0052686	perillic acid-CoA ligase (AMP-forming) activity	molecular_function	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA.
GO:0052687	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity	molecular_function	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
GO:0052688	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity	molecular_function	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
GO:0052689	carboxylic ester hydrolase activity	molecular_function	Catalysis of the hydrolysis of a carboxylic ester bond.
GO:0052690	trichloro-p-hydroquinone reductive dehalogenase activity	molecular_function	Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.
GO:0052691	UDP-arabinopyranose mutase activity	molecular_function	Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.
GO:0052692	raffinose alpha-galactosidase activity	molecular_function	Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose.
GO:0052693	epoxyqueuosine reductase activity	molecular_function	Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.
GO:0052694	jasmonoyl-isoleucine-12-hydroxylase activity	molecular_function	Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O.
GO:0052695	cellular glucuronidation	biological_process	The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.
GO:0052696	flavonoid glucuronidation	biological_process	The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.
GO:0052697	xenobiotic glucuronidation	biological_process	The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.
GO:0052698	ergothioneine metabolic process	biological_process	The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
GO:0052699	ergothioneine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
GO:0052700	ergothioneine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
GO:0052701	cellular modified histidine metabolic process	biological_process	The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0052702	cellular modified histidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0052703	cellular modified histidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
GO:0052704	ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide	biological_process	The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate.
GO:0052705	methylhistidine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine.
GO:0052706	histidine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.
GO:0052707	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine	biological_process	The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).
GO:0052708	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process	biological_process	The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
GO:0052709	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
GO:0052710	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
GO:0052712	inositol phosphosphingolipid phospholipase activity	molecular_function	Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.
GO:0052713	inositol phosphorylceramide phospholipase activity	molecular_function	Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.
GO:0052714	mannosyl-inositol phosphorylceramide phospholipase activity	molecular_function	Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.
GO:0052715	mannosyl-diinositol phosphorylceramide phospholipase activity	molecular_function	Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol.
GO:0052716	hydroquinone:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.
GO:0052717	tRNA-specific adenosine-34 deaminase activity	molecular_function	Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule.
GO:0052718	tRNA-specific adenosine-34 deaminase complex	cellular_component	A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human.
GO:0052719	apurinic/apyrimidinic endoribonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.
GO:0052720	class II DNA-(apurinic or apyrimidinic site) endonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
GO:0052722	fatty acid in-chain hydroxylase activity	molecular_function	Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.
GO:0052723	inositol hexakisphosphate 1-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate.
GO:0052724	inositol hexakisphosphate 3-kinase activity	molecular_function	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.
GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H+.
GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H+.
GO:0052727	capsanthin synthase activity	molecular_function	Catalysis of the reaction: antheraxanthin = capsanthin.
GO:0052728	capsorubin synthase activity	molecular_function	Catalysis of the reaction: violaxanthin = capsorubin.
GO:0052729	dimethylglycine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.
GO:0052730	sarcosine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.
GO:0052731	phosphocholine phosphatase activity	molecular_function	Catalysis of the reaction: choline phosphate + H2O = choline + phosphate.
GO:0052732	phosphoethanolamine phosphatase activity	molecular_function	Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate.
GO:0052733	quinate 3-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+.
GO:0052734	shikimate 3-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.
GO:0052735	tRNA (cytosine-3-)-methyltransferase activity	molecular_function	Catalysis of the reaction: a cytidine in tRNA + S-adenosyl-L-methionine = an N3-methylcytidine in tRNA + H+ + S-adenosyl-L-homocysteine.
GO:0052736	beta-glucanase activity	molecular_function	Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds.
GO:0052737	pyruvate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.
GO:0052738	oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.
GO:0052739	phosphatidylserine 1-acylhydrolase activity	molecular_function	Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid.
GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity	molecular_function	Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate.
GO:0052741	(R)-limonene 6-monooxygenase activity	molecular_function	Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+.
GO:0052742	phosphatidylinositol kinase activity	molecular_function	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate.
GO:0052743	inositol tetrakisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidyl-1D-myo-inositol monophosphate + H2O = phosphatidylinositol + phosphate.
GO:0052745	inositol phosphate phosphatase activity	molecular_function	Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.
GO:0052747	sinapyl alcohol dehydrogenase activity	molecular_function	Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+.
GO:0052748	baicalin beta-D-glucuronidase activity	molecular_function	Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.
GO:0052749	glucose-6-phosphate dehydrogenase (coenzyme F420) activity	molecular_function	Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.
GO:0052750	reactive-black-5:hydrogen-peroxide oxidoreductase activity	molecular_function	Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O.
GO:0052751	GDP-mannose hydrolase activity	molecular_function	Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.
GO:0052752	reduced coenzyme F420:heterodisulfide oxidoreductase activity	molecular_function	Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH.
GO:0052753	propan-2-ol:coenzyme F420 oxidoreductase activity	molecular_function	Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420.
GO:0052754	GTP:coenzyme F420 guanyltransferase activity	molecular_function	Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.
GO:0052755	reduced coenzyme F420:quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.
GO:0052756	chitobiose phosphorylase activity	molecular_function	Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.
GO:0052757	chondroitin hydrolase activity	molecular_function	Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].
GO:0052758	coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity	molecular_function	Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.
GO:0052759	coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity	molecular_function	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction.
GO:0052760	coenzyme F420-dependent 2,4-dinitrophenol reductase activity	molecular_function	Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.
GO:0052761	exo-1,4-beta-D-glucosaminidase activity	molecular_function	Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.
GO:0052762	gellan lyase activity	molecular_function	Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).
GO:0052763	ulvan lyase activity	molecular_function	Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.
GO:0052764	exo-oligoalginate lyase activity	molecular_function	Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
GO:0052765	reduced coenzyme F420 oxidase activity	molecular_function	Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.
GO:0052766	mannoside alpha-1,4-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
GO:0052767	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
GO:0052768	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity	molecular_function	Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
GO:0052769	beta-6-sulfate-N-acetylglucosaminidase activity	molecular_function	Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.
GO:0052770	coenzyme F390-A hydrolase activity	molecular_function	Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420.
GO:0052771	coenzyme F390-G hydrolase activity	molecular_function	Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420.
GO:0052772	brefeldin A esterase activity	molecular_function	Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.
GO:0052773	diacetylchitobiose deacetylase activity	molecular_function	Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc).
GO:0052774	glucosyl-N-acetylglucosamine glucosaminidase activity	molecular_function	Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.
GO:0052775	endo-1,3-alpha-L-rhamnosidase activity	molecular_function	Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.
GO:0052776	diacetylchitobiose catabolic process to glucosamine and acetate	biological_process	The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.
GO:0052777	diacetylchitobiose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.
GO:0052778	diacetylchitobiose metabolic process	biological_process	The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose.
GO:0052779	amino disaccharide metabolic process	biological_process	The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
GO:0052780	chitobiose metabolic process	biological_process	The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.
GO:0052781	chitobiose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.
GO:0052782	amino disaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
GO:0052783	reuteran metabolic process	biological_process	The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.
GO:0052784	reuteran biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.
GO:0052785	cellulose catabolism by endo-processive cellulases	biological_process	The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.
GO:0052786	alpha-linked polysaccharide catabolism to maltotriose	biological_process	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.
GO:0052787	alpha-linked polysaccharide catabolism to maltopentaose	biological_process	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.
GO:0052788	d-4,5 unsaturated beta-glucuronyl hydrolase activity	molecular_function	Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.
GO:0052789	mannan 1,3-beta-mannosidase activity	molecular_function	Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.
GO:0052790	chitooligosaccharide deacetylase activity	molecular_function	Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.
GO:0052791	3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity	molecular_function	Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain.
GO:0052792	endo-xylogalacturonan hydrolase activity	molecular_function	Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position.
GO:0052793	pectin acetylesterase activity	molecular_function	Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.
GO:0052794	exo-alpha-(2->3)-sialidase activity	molecular_function	Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.
GO:0052795	exo-alpha-(2->6)-sialidase activity	molecular_function	Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates.
GO:0052796	exo-alpha-(2->8)-sialidase activity	molecular_function	Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.
GO:0052797	4-O-methyl-glucuronoyl methylesterase activity	molecular_function	Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].
GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity	molecular_function	Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.
GO:0052799	coenzyme F420-dependent bicyclic nitroimidazole catabolic process	biological_process	The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.
GO:0052800	bicyclic nitroimidazole catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.
GO:0052801	bicyclic nitroimidazole metabolic process	biological_process	The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.
GO:0052802	nitroimidazole metabolic process	biological_process	The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.
GO:0052803	imidazole-containing compound metabolic process	biological_process	The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
GO:0052804	nitroimidazole catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.
GO:0052805	imidazole-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
GO:0052806	sulfite reductase (coenzyme F420) activity	molecular_function	Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
GO:0052807	aflatoxin reductase (coenzyme F420) activity	molecular_function	Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
GO:0052808	reduced coenzyme F420:NADP+ oxidoreductase activity	molecular_function	Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
GO:0052809	acharan sulfate lyase activity	molecular_function	Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid.
GO:0052810	1-phosphatidylinositol-5-kinase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H+.
GO:0052811	1-phosphatidylinositol-3-phosphate 4-kinase activity	molecular_function	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H+.
GO:0052814	medium-chain-aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.
GO:0052815	medium-chain acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length.
GO:0052816	long-chain acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.
GO:0052817	very long chain acyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18.
GO:0052818	heteroglycan 3-alpha-mannosyltransferase activity	molecular_function	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP.
GO:0052819	heteroglycan 2-alpha-mannosyltransferase activity	molecular_function	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP.
GO:0052820	DNA-1,N6-ethenoadenine N-glycosylase activity	molecular_function	Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.
GO:0052821	DNA-7-methyladenine glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.
GO:0052822	DNA-3-methylguanine glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.
GO:0052823	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity	molecular_function	Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+.
GO:0052825	inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.
GO:0052826	inositol hexakisphosphate 2-phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.
GO:0052827	inositol pentakisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.
GO:0052828	inositol-3,4-bisphosphate 4-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.
GO:0052829	inositol-1,3,4-trisphosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.
GO:0052830	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.
GO:0052831	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	molecular_function	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.
GO:0052832	inositol monophosphate 3-phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.
GO:0052833	inositol monophosphate 4-phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.
GO:0052834	inositol monophosphate phosphatase activity	molecular_function	Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.
GO:0052835	inositol-3,4,6-trisphosphate 1-kinase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H+.
GO:0052836	inositol 5-diphosphate pentakisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate.
GO:0052837	thiazole biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.
GO:0052838	thiazole metabolic process	biological_process	The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.
GO:0052839	inositol diphosphate tetrakisphosphate kinase activity	molecular_function	Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate.
GO:0052840	inositol diphosphate tetrakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: diphospho-1D-myo-inositol tetrakisphosphate + H2O = 1D-myo-inositol pentakisphosphate + phosphate.
GO:0052841	inositol bisdiphosphate tetrakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: bisdiphospho-1D-myo-inositol tetrakisphosphate + H2O = diphospho-1D-myo-inositol pentakisphosphate + phosphate.
GO:0052842	inositol diphosphate pentakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.
GO:0052843	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.
GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.
GO:0052845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + H+.
GO:0052846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	molecular_function	Catalysis of the reaction: 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.
GO:0052847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	molecular_function	Catalysis of the reaction: 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+.
GO:0052848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	molecular_function	Catalysis of the reaction: 3,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H+.
GO:0052849	NADPH-dependent curcumin reductase activity	molecular_function	Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+.
GO:0052850	NADPH-dependent dihydrocurcumin reductase activity	molecular_function	Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+.
GO:0052851	ferric-chelate reductase (NADPH) activity	molecular_function	Catalysis of the reaction: 2 Fe3+-siderophore + NADP+ + H+ -> 2 Fe2+-siderophore + NADPH.
GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity	molecular_function	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H+ + NADH + phosphate.
GO:0052856	NADHX epimerase activity	molecular_function	Catalysis of the reaction: (R)-NADHX = (S)-NADHX.
GO:0052857	NADPHX epimerase activity	molecular_function	Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX.
GO:0052858	peptidyl-lysine acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
GO:0052859	glucan endo-1,4-beta-glucosidase activity	molecular_function	Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans.
GO:0052860	2'-deoxymugineic-acid 3-dioxygenase activity	molecular_function	Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2.
GO:0052861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group	molecular_function	Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.
GO:0052862	glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group	molecular_function	Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.
GO:0052863	1-deoxy-D-xylulose 5-phosphate metabolic process	biological_process	The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
GO:0052864	1-deoxy-D-xylulose 5-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
GO:0052865	1-deoxy-D-xylulose 5-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
GO:0052866	phosphatidylinositol phosphate phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.
GO:0052867	phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.
GO:0052868	protein-lysine lysyltransferase activity	molecular_function	Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.
GO:0052869	arachidonic acid omega-hydroxylase activity	molecular_function	Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.
GO:0052870	tocopherol omega-hydroxylase activity	molecular_function	Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O .
GO:0052871	alpha-tocopherol omega-hydroxylase activity	molecular_function	Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O .
GO:0052872	tocotrienol omega-hydroxylase activity	molecular_function	Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O .
GO:0052873	FMN reductase (NADPH) activity	molecular_function	Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.
GO:0052874	FMN reductase (NADH) activity	molecular_function	Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.
GO:0052875	riboflavin reductase (NAD(P)H) activity	molecular_function	Catalysis of the reaction: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+. This reaction can utilize NADH and NADPH.
GO:0052876	methylamine dehydrogenase (amicyanin) activity	molecular_function	Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin].
GO:0052877	oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.
GO:0052878	linoleate 8R-lipoxygenase activity	molecular_function	Catalysis of the reaction: O2 + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.
GO:0052879	9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity	molecular_function	Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate.
GO:0052880	oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.
GO:0052881	4-hydroxyphenylacetate 3-monooxygenase activity	molecular_function	Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O2 = 3,4-dihydroxyphenylacetate + FAD + H+ + H2O.
GO:0052882	oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.
GO:0052883	tyrosine ammonia-lyase activity	molecular_function	Catalysis of the reaction: L-tyrosine = NH4 + trans-4-coumarate.
GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity	molecular_function	Catalysis of the reaction: H2O + all-trans-retinyl palmitate = 11-cis-retinol + H+ + palmitate.
GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	molecular_function	Catalysis of the reaction: H2O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.
GO:0052886	9,9'-dicis-carotene:quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol.
GO:0052887	7,9,9'-tricis-neurosporene:quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol.
GO:0052889	9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene	biological_process	The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene.
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.
GO:0052891	aliphatic (S)-hydroxynitrile lyase activity	molecular_function	Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.
GO:0052892	aromatic (S)-hydroxynitrile lyase activity	molecular_function	Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.
GO:0052893	N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	molecular_function	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide.
GO:0052894	norspermine:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.
GO:0052895	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity	molecular_function	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide.
GO:0052896	spermidine oxidase (propane-1,3-diamine-forming) activity	molecular_function	Catalysis of the reaction: H2O + O2 + spermidine = 1,3-diaminopropane + 4-aminobutanal + H2O2.
GO:0052897	N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	molecular_function	Catalysis of the reaction: H2O + N(8)-acetylspermidine + O2 = 1,3-diaminopropane + 4-acetamidobutanal + H2O2.
GO:0052899	N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	molecular_function	Catalysis of the reaction: H2O + N(1),N(12)-diacetylspermine + O2 = 3-acetamidopropanal + H2O2 + N(1)-acetylspermidine.
GO:0052900	spermine oxidase (propane-1,3-diamine-forming) activity	molecular_function	Catalysis of the reaction: H2O + O2 + spermine = 1,3-diaminopropane + H2O2 + N-(3-aminopropyl)-4-aminobutanal.
GO:0052901	spermine:oxygen oxidoreductase (spermidine-forming) activity	molecular_function	Catalysis of the reaction: H2O + O2 + spermine = 3-aminopropanal + H2O2 + spermidine.
GO:0052902	spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity	molecular_function	Catalysis of the reaction: H2O + O2 + spermidine = 3-aminopropanal + H2O2 + putrescine.
GO:0052903	N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	molecular_function	Catalysis of the reaction: H2O + N(1)-acetylspermine + O2 = 3-acetamidopropanal + H2O2 + spermidine.
GO:0052904	N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	molecular_function	Catalysis of the reaction: H2O + N(1)-acetylspermidine + O2 = 3-acetamidopropanal + H2O2 + putrescine.
GO:0052905	tRNA (guanine(9)-N(1))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine.
GO:0052906	tRNA (guanine(37)-N(1))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.
GO:0052907	23S rRNA (adenine(1618)-N(6))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.
GO:0052908	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	molecular_function	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.
GO:0052909	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	molecular_function	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.
GO:0052910	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.
GO:0052911	23S rRNA (guanine(745)-N(1))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.
GO:0052912	23S rRNA (guanine(748)-N(1))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.
GO:0052913	16S rRNA (guanine(966)-N(2))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.
GO:0052914	16S rRNA (guanine(1207)-N(2))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine.
GO:0052915	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
GO:0052916	23S rRNA (guanine(1835)-N(2))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine.
GO:0052917	dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase	molecular_function	Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.
GO:0052918	dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
GO:0052919	aliphatic (R)-hydroxynitrile lyase activity	molecular_function	Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.
GO:0052922	hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.
GO:0052923	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.
GO:0052924	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity	molecular_function	Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.
GO:0052925	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity	molecular_function	Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
GO:0052926	dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	molecular_function	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
GO:0052927	CTP:tRNA cytidylyltransferase activity	molecular_function	Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' CC end + 2 diphosphate.
GO:0052929	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	molecular_function	Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.
GO:0052933	alcohol dehydrogenase (cytochrome c(L)) activity	molecular_function	Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.
GO:0052934	alcohol dehydrogenase (cytochrome c) activity	molecular_function	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.
GO:0055001	muscle cell development	biological_process	The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.
GO:0055002	striated muscle cell development	biological_process	The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
GO:0055003	cardiac myofibril assembly	biological_process	The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
GO:0055004	atrial cardiac myofibril assembly	biological_process	The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
GO:0055005	ventricular cardiac myofibril assembly	biological_process	The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
GO:0055006	cardiac cell development	biological_process	The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.
GO:0055007	cardiac muscle cell differentiation	biological_process	The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
GO:0055008	cardiac muscle tissue morphogenesis	biological_process	The process in which the anatomical structures of cardiac muscle tissue are generated and organized.
GO:0055009	atrial cardiac muscle tissue morphogenesis	biological_process	The process in which the anatomical structure of cardiac atrium muscle is generated and organized.
GO:0055010	ventricular cardiac muscle tissue morphogenesis	biological_process	The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.
GO:0055011	atrial cardiac muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
GO:0055012	ventricular cardiac muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
GO:0055013	cardiac muscle cell development	biological_process	The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.
GO:0055014	atrial cardiac muscle cell development	biological_process	The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
GO:0055015	ventricular cardiac muscle cell development	biological_process	The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
GO:0055016	hypochord development	biological_process	The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.
GO:0055017	cardiac muscle tissue growth	biological_process	The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
GO:0055018	regulation of cardiac muscle fiber development	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.
GO:0055019	negative regulation of cardiac muscle fiber development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.
GO:0055020	positive regulation of cardiac muscle fiber development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.
GO:0055021	regulation of cardiac muscle tissue growth	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle growth.
GO:0055022	negative regulation of cardiac muscle tissue growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.
GO:0055023	positive regulation of cardiac muscle tissue growth	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.
GO:0055024	regulation of cardiac muscle tissue development	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.
GO:0055025	positive regulation of cardiac muscle tissue development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.
GO:0055026	negative regulation of cardiac muscle tissue development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.
GO:0055028	cortical microtubule	cellular_component	Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.
GO:0055029	nuclear DNA-directed RNA polymerase complex	cellular_component	A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.
GO:0055034	Bolwig's organ development	biological_process	The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
GO:0055035	plastid thylakoid membrane	cellular_component	The lipid bilayer membrane of any thylakoid within a plastid.
GO:0055036	virion membrane	cellular_component	The lipid bilayer surrounding a virion.
GO:0055037	recycling endosome	cellular_component	An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
GO:0055038	recycling endosome membrane	cellular_component	The lipid bilayer surrounding a recycling endosome.
GO:0055039	trichocyst	cellular_component	A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft.
GO:0055040	periplasmic flagellum	cellular_component	Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella.
GO:0055041	cyclopentanol dehydrogenase activity	molecular_function	Catalysis of the reaction: cyclopentanol + NAD+ = cyclopentanone + H+ + NADH.
GO:0055042	5-valerolactone hydrolase activity	molecular_function	Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.
GO:0055043	5-oxovalerate dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+.
GO:0055044	symplast	cellular_component	The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.
GO:0055045	antipodal cell degeneration	biological_process	The process in which the antipodal cells undergo programmed cell death.
GO:0055046	microgametogenesis	biological_process	The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.
GO:0055047	generative cell mitosis	biological_process	The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.
GO:0055048	anastral spindle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.
GO:0055051	ATP-binding cassette (ABC) transporter complex, integrated substrate binding	cellular_component	A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	cellular_component	A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
GO:0055053	mannose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.
GO:0055054	fructose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.
GO:0055055	D-glucose:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose.
GO:0055056	D-glucose transmembrane transporter activity	molecular_function	Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.
GO:0055057	neuroblast division	biological_process	The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.
GO:0055058	symmetric neuroblast division	biological_process	The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells.
GO:0055059	asymmetric neuroblast division	biological_process	The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
GO:0055060	asymmetric neuroblast division resulting in ganglion mother cell formation	biological_process	Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.
GO:0055062	phosphate ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
GO:0055063	sulfate ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.
GO:0055064	chloride ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.
GO:0055068	cobalt ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell.
GO:0055070	copper ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
GO:0055071	manganese ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.
GO:0055074	calcium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
GO:0055075	potassium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
GO:0055077	gap junction hemi-channel activity	molecular_function	A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.
GO:0055078	sodium ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
GO:0055080	monoatomic cation homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.
GO:0055081	monoatomic anion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of monoatomic anions within an organism or cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom.
GO:0055082	intracellular chemical homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell.
GO:0055085	transmembrane transport	biological_process	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0055086	nucleobase-containing small molecule metabolic process	biological_process	The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GO:0055087	Ski complex	cellular_component	A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.
GO:0055088	lipid homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
GO:0055089	fatty acid homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.
GO:0055090	acylglycerol homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.
GO:0055091	phospholipid homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.
GO:0055092	sterol homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
GO:0055093	response to hyperoxia	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
GO:0055094	response to lipoprotein particle	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.
GO:0055095	lipoprotein particle mediated signaling	biological_process	The series of molecular signals mediated by the detection of a lipoprotein particle.
GO:0055096	low-density lipoprotein particle mediated signaling	biological_process	The series of molecular signals mediated by the detection of low-density lipoprotein particle.
GO:0055097	high density lipoprotein particle mediated signaling	biological_process	The series of molecular signals mediated by the detection of high density lipoprotein particle.
GO:0055100	adiponectin binding	molecular_function	Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.
GO:0055102	lipase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
GO:0055103	ligase regulator activity	molecular_function	Binds to and modulates the activity of a ligase.
GO:0055104	ligase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a ligase.
GO:0055105	ubiquitin-protein transferase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.
GO:0055106	ubiquitin-protein transferase regulator activity	molecular_function	Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
GO:0055107	Golgi to secretory granule transport	biological_process	The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.
GO:0055108	Golgi to transport vesicle transport	biological_process	The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.
GO:0055109	invagination involved in gastrulation with mouth forming second	biological_process	The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.
GO:0055110	involution involved in gastrulation with mouth forming second	biological_process	The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.
GO:0055111	ingression involved in gastrulation with mouth forming second	biological_process	The migration of individual cells into the embryo involved in deuterostomic gastrulation.
GO:0055112	delamination involved in gastrulation with mouth forming second	biological_process	The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation.
GO:0055113	epiboly involved in gastrulation with mouth forming second	biological_process	The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
GO:0055115	entry into diapause	biological_process	The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
GO:0055116	entry into reproductive diapause	biological_process	The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0055117	regulation of cardiac muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle contraction.
GO:0055118	negative regulation of cardiac muscle contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.
GO:0055119	relaxation of cardiac muscle	biological_process	The process in which the extent of cardiac muscle contraction is reduced.
GO:0055120	striated muscle dense body	cellular_component	A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
GO:0055121	response to high fluence blue light stimulus by blue high-fluence system	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2.
GO:0055122	response to very low light intensity stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
GO:0055123	digestive system development	biological_process	The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0055127	vibrational conductance of sound to the inner ear	biological_process	The transmission of vibrations via ossicles to the inner ear.
GO:0055129	L-proline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
GO:0055130	D-alanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine.
GO:0055131	C3HC4-type RING finger domain binding	molecular_function	Binding to a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
GO:0060001	minus-end directed microfilament motor activity	molecular_function	A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.
GO:0060002	plus-end directed microfilament motor activity	molecular_function	A motor activity that generates movement along a microfilament towards the plus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.
GO:0060003	copper ion export	biological_process	The directed movement of copper ions out of a cell or organelle.
GO:0060004	reflex	biological_process	An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.
GO:0060005	vestibular reflex	biological_process	A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
GO:0060006	angular vestibuloocular reflex	biological_process	A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
GO:0060007	linear vestibuloocular reflex	biological_process	A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
GO:0060008	Sertoli cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
GO:0060009	Sertoli cell development	biological_process	The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
GO:0060010	Sertoli cell fate commitment	biological_process	The process in which the cellular identity of Sertoli cells is acquired and determined.
GO:0060011	Sertoli cell proliferation	biological_process	The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
GO:0060012	synaptic transmission, glycinergic	biological_process	The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0060013	righting reflex	biological_process	A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
GO:0060014	granulosa cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
GO:0060015	granulosa cell fate commitment	biological_process	The cell fate commitment of precursor cells that will become granulosa cells.
GO:0060016	granulosa cell development	biological_process	The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.
GO:0060017	parathyroid gland development	biological_process	The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.
GO:0060018	astrocyte fate commitment	biological_process	The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.
GO:0060019	radial glial cell differentiation	biological_process	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0060020	Bergmann glial cell differentiation	biological_process	The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0060021	roof of mouth development	biological_process	The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
GO:0060022	hard palate development	biological_process	The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
GO:0060023	soft palate development	biological_process	The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.
GO:0060024	rhythmic synaptic transmission	biological_process	Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
GO:0060025	regulation of synaptic activity	biological_process	Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
GO:0060026	convergent extension	biological_process	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
GO:0060027	convergent extension involved in gastrulation	biological_process	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
GO:0060028	convergent extension involved in axis elongation	biological_process	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
GO:0060029	convergent extension involved in organogenesis	biological_process	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.
GO:0060030	dorsal convergence	biological_process	The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
GO:0060031	mediolateral intercalation	biological_process	The interdigitation of cells along the mediolateral axis during gastrulation.
GO:0060032	notochord regression	biological_process	The developmental process in which the stucture of the notochord is destroyed in an embryo.
GO:0060033	anatomical structure regression	biological_process	The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.
GO:0060034	notochord cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
GO:0060035	notochord cell development	biological_process	The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060036	notochord cell vacuolation	biological_process	The assembly and arrangement of a vacuole within a cell of the notochord.
GO:0060037	pharyngeal system development	biological_process	The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
GO:0060038	cardiac muscle cell proliferation	biological_process	The expansion of a cardiac muscle cell population by cell division.
GO:0060039	pericardium development	biological_process	The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
GO:0060040	retinal bipolar neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.
GO:0060041	retina development in camera-type eye	biological_process	The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
GO:0060042	retina morphogenesis in camera-type eye	biological_process	The process in which the anatomical structure of the retina is generated and organized.
GO:0060043	regulation of cardiac muscle cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
GO:0060044	negative regulation of cardiac muscle cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.
GO:0060045	positive regulation of cardiac muscle cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
GO:0060046	regulation of acrosome reaction	biological_process	Any process that modulates the frequency, rate or extent of the acrosome reaction.
GO:0060047	heart contraction	biological_process	The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
GO:0060048	cardiac muscle contraction	biological_process	Muscle contraction of cardiac muscle tissue.
GO:0060049	regulation of protein glycosylation	biological_process	Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GO:0060050	positive regulation of protein glycosylation	biological_process	Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GO:0060051	negative regulation of protein glycosylation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
GO:0060052	neurofilament cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
GO:0060053	neurofilament cytoskeleton	cellular_component	Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	biological_process	Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
GO:0060055	angiogenesis involved in wound healing	biological_process	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
GO:0060056	mammary gland involution	biological_process	The tissue remodeling that removes differentiated mammary epithelia during weaning.
GO:0060057	apoptotic process involved in mammary gland involution	biological_process	Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.
GO:0060058	positive regulation of apoptotic process involved in mammary gland involution	biological_process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.
GO:0060059	embryonic retina morphogenesis in camera-type eye	biological_process	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	biological_process	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage.
GO:0060061	Spemann organizer formation	biological_process	Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.
GO:0060062	Spemann organizer formation at the dorsal lip of the blastopore	biological_process	Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.
GO:0060063	Spemann organizer formation at the embryonic shield	biological_process	Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.
GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	biological_process	Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.
GO:0060065	uterus development	biological_process	The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
GO:0060066	oviduct development	biological_process	The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
GO:0060067	cervix development	biological_process	The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.
GO:0060068	vagina development	biological_process	The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.
GO:0060069	Wnt signaling pathway, regulating spindle positioning	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.
GO:0060070	canonical Wnt signaling pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
GO:0060072	large conductance calcium-activated potassium channel activity	molecular_function	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
GO:0060073	micturition	biological_process	The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
GO:0060074	synapse maturation	biological_process	The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
GO:0060075	regulation of resting membrane potential	biological_process	Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
GO:0060076	excitatory synapse	cellular_component	A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
GO:0060077	inhibitory synapse	cellular_component	A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
GO:0060078	regulation of postsynaptic membrane potential	biological_process	Any process that modulates the potential difference across a post-synaptic membrane.
GO:0060079	excitatory postsynaptic potential	biological_process	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
GO:0060080	inhibitory postsynaptic potential	biological_process	A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
GO:0060081	membrane hyperpolarization	biological_process	The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
GO:0060082	eye blink reflex	biological_process	The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.
GO:0060083	smooth muscle contraction involved in micturition	biological_process	The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.
GO:0060084	synaptic transmission involved in micturition	biological_process	The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.
GO:0060085	smooth muscle relaxation of the bladder outlet	biological_process	A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.
GO:0060086	circadian temperature homeostasis	biological_process	Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.
GO:0060087	relaxation of vascular associated smooth muscle	biological_process	A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
GO:0060088	auditory receptor cell stereocilium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
GO:0060089	molecular transducer activity	molecular_function	A compound molecular function in which an effector function is controlled by one or more regulatory components.
GO:0060090	molecular adaptor activity	molecular_function	The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0060091	kinocilium	cellular_component	A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.
GO:0060092	regulation of synaptic transmission, glycinergic	biological_process	Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
GO:0060093	negative regulation of synaptic transmission, glycinergic	biological_process	Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
GO:0060094	positive regulation of synaptic transmission, glycinergic	biological_process	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
GO:0060095	zinc potentiation of synaptic transmission, glycinergic	biological_process	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
GO:0060096	serotonin secretion, neurotransmission	biological_process	The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.
GO:0060097	cytoskeletal rearrangement involved in phagocytosis, engulfment	biological_process	The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
GO:0060098	membrane reorganization involved in phagocytosis, engulfment	biological_process	The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
GO:0060099	regulation of phagocytosis, engulfment	biological_process	Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
GO:0060100	positive regulation of phagocytosis, engulfment	biological_process	Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
GO:0060101	negative regulation of phagocytosis, engulfment	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
GO:0060102	collagen and cuticulin-based cuticle extracellular matrix	cellular_component	A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.
GO:0060104	surface coat of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans.
GO:0060105	epicuticle of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans.
GO:0060106	cortical layer of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.
GO:0060107	annuli extracellular matrix	cellular_component	The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present.
GO:0060108	annular furrow extracellular matrix	cellular_component	The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.
GO:0060109	medial layer of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.
GO:0060110	basal layer of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans.
GO:0060111	alae of collagen and cuticulin-based cuticle extracellular matrix	cellular_component	Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.
GO:0060112	generation of ovulation cycle rhythm	biological_process	The process which controls the timing of the type of sexual cycle seen in female mammals.
GO:0060113	inner ear receptor cell differentiation	biological_process	The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.
GO:0060114	vestibular receptor cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.
GO:0060115	vestibular receptor cell fate commitment	biological_process	The process in which a cell becomes committed to become a vestibular receptor cell.
GO:0060116	vestibular receptor cell morphogenesis	biological_process	Any process that alters the size or shape of a vestibular receptor cell.
GO:0060117	auditory receptor cell development	biological_process	The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060118	vestibular receptor cell development	biological_process	The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060119	inner ear receptor cell development	biological_process	The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060120	inner ear receptor cell fate commitment	biological_process	The process in which a cell becomes committed to become an inner ear receptor cell.
GO:0060121	vestibular receptor cell stereocilium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells.
GO:0060122	inner ear receptor cell stereocilium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
GO:0060123	regulation of growth hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.
GO:0060124	positive regulation of growth hormone secretion	biological_process	Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.
GO:0060125	negative regulation of growth hormone secretion	biological_process	Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.
GO:0060126	somatotropin secreting cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
GO:0060127	prolactin secreting cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.
GO:0060128	corticotropin hormone secreting cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.
GO:0060130	thyroid-stimulating hormone-secreting cell development	biological_process	The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.
GO:0060131	corticotropin hormone secreting cell development	biological_process	The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
GO:0060132	prolactin secreting cell development	biological_process	The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.
GO:0060133	somatotropin secreting cell development	biological_process	The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
GO:0060134	prepulse inhibition	biological_process	The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
GO:0060135	maternal process involved in female pregnancy	biological_process	A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.
GO:0060136	embryonic process involved in female pregnancy	biological_process	A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.
GO:0060137	maternal process involved in parturition	biological_process	A reproductive process occurring in the mother that results in birth.
GO:0060138	fetal process involved in parturition	biological_process	A reproductive process occurring in the embryo that results in birth.
GO:0060140	modulation by virus of syncytium formation via plasma membrane fusion	biological_process	The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0060141	positive regulation of syncytium formation by virus	biological_process	The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0060142	regulation of syncytium formation by plasma membrane fusion	biological_process	Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	biological_process	Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
GO:0060147	regulation of post-transcriptional gene silencing	biological_process	Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GO:0060148	positive regulation of post-transcriptional gene silencing	biological_process	Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GO:0060149	negative regulation of post-transcriptional gene silencing	biological_process	Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
GO:0060151	peroxisome localization	biological_process	Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GO:0060152	microtubule-based peroxisome localization	biological_process	The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GO:0060153	perturbation by virus of host cell cycle progression	biological_process	A process in which a virus interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0060155	platelet dense granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.
GO:0060156	milk ejection reflex	biological_process	A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.
GO:0060157	urinary bladder development	biological_process	The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.
GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	biological_process	A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0060159	regulation of dopamine receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
GO:0060160	negative regulation of dopamine receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
GO:0060161	positive regulation of dopamine receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
GO:0060162	negative regulation of phospholipase C-activating dopamine receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway.
GO:0060163	subpallium neuron fate commitment	biological_process	The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.
GO:0060164	regulation of timing of neuron differentiation	biological_process	The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.
GO:0060165	regulation of timing of subpallium neuron differentiation	biological_process	The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.
GO:0060166	olfactory pit development	biological_process	The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.
GO:0060167	regulation of adenosine receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
GO:0060168	positive regulation of adenosine receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
GO:0060169	negative regulation of adenosine receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
GO:0060170	ciliary membrane	cellular_component	The portion of the plasma membrane surrounding a cilium.
GO:0060171	stereocilium membrane	cellular_component	The portion of the plasma membrane surrounding a stereocilium.
GO:0060172	astral microtubule depolymerization	biological_process	The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
GO:0060173	limb development	biological_process	The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
GO:0060174	limb bud formation	biological_process	The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
GO:0060175	brain-derived neurotrophic factor receptor activity	molecular_function	Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
GO:0060176	regulation of aggregation involved in sorocarp development	biological_process	Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
GO:0060177	regulation of angiotensin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.
GO:0060178	regulation of exocyst localization	biological_process	Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
GO:0060179	male mating behavior	biological_process	The specific behavior of a male organism that is associated with reproduction.
GO:0060180	female mating behavior	biological_process	The specific behavior of a female organism that is associated with reproduction.
GO:0060182	apelin receptor activity	molecular_function	Combining with the peptide apelin to initiate a change in cell activity.
GO:0060183	apelin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by apelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0060184	cell cycle switching	biological_process	The process in which a cell switches cell cycle mode.
GO:0060185	outer ear unfolding	biological_process	The opening and spreading out of the outer ear.
GO:0060186	outer ear emergence	biological_process	The growth of the outer ear.
GO:0060187	cell pole	cellular_component	Either of two different areas at opposite ends of an axis of a cell.
GO:0060188	regulation of protein desumoylation	biological_process	Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
GO:0060189	positive regulation of protein desumoylation	biological_process	Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
GO:0060190	negative regulation of protein desumoylation	biological_process	Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
GO:0060191	regulation of lipase activity	biological_process	Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
GO:0060192	negative regulation of lipase activity	biological_process	Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
GO:0060193	positive regulation of lipase activity	biological_process	Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
GO:0060194	regulation of antisense RNA transcription	biological_process	Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
GO:0060195	negative regulation of antisense RNA transcription	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
GO:0060196	positive regulation of antisense RNA transcription	biological_process	Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
GO:0060197	cloacal septation	biological_process	The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.
GO:0060198	clathrin-sculpted vesicle	cellular_component	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release.
GO:0060199	clathrin-sculpted glutamate transport vesicle	cellular_component	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.
GO:0060200	clathrin-sculpted acetylcholine transport vesicle	cellular_component	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine.
GO:0060201	clathrin-sculpted acetylcholine transport vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.
GO:0060202	clathrin-sculpted acetylcholine transport vesicle lumen	cellular_component	The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle.
GO:0060203	clathrin-sculpted glutamate transport vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle.
GO:0060204	clathrin-sculpted glutamate transport vesicle lumen	cellular_component	The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.
GO:0060205	cytoplasmic vesicle lumen	cellular_component	The volume enclosed by a cytoplasmic vesicle.
GO:0060206	estrous cycle phase	biological_process	The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.
GO:0060207	diestrus	biological_process	The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.
GO:0060208	proestrus	biological_process	The estrous cycle phase in which there is heightened follicular activity.
GO:0060209	estrus	biological_process	The estrous cycle phase in which a female is sexually receptive.
GO:0060210	metestrus	biological_process	The estrous cycle phase in which there is subsiding follicular function.
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	biological_process	Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	biological_process	Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	biological_process	Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
GO:0060214	endocardium formation	biological_process	Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0060215	primitive hemopoiesis	biological_process	A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
GO:0060216	definitive hemopoiesis	biological_process	A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
GO:0060217	hemangioblast cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
GO:0060218	hematopoietic stem cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
GO:0060219	camera-type eye photoreceptor cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
GO:0060220	camera-type eye photoreceptor cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.
GO:0060221	retinal rod cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
GO:0060222	regulation of retinal cone cell fate commitment	biological_process	Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
GO:0060223	retinal rod cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
GO:0060224	regulation of retinal rod cell fate commitment	biological_process	Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
GO:0060225	positive regulation of retinal rod cell fate commitment	biological_process	Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
GO:0060226	negative regulation of retinal cone cell fate commitment	biological_process	Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
GO:0060227	Notch signaling pathway involved in camera-type eye photoreceptor fate commitment	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.
GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	molecular_function	Binds to and increases the activity of phosphatidylcholine-sterol O-acyltransferase.
GO:0060229	lipase activator activity	molecular_function	Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
GO:0060230	lipoprotein lipase activator activity	molecular_function	Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
GO:0060231	mesenchymal to epithelial transition	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
GO:0060232	delamination	biological_process	The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.
GO:0060233	oenocyte delamination	biological_process	The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet.
GO:0060234	neuroblast delamination	biological_process	The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.
GO:0060235	lens induction in camera-type eye	biological_process	Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.
GO:0060236	regulation of mitotic spindle organization	biological_process	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
GO:0060237	regulation of fungal-type cell wall organization	biological_process	Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
GO:0060238	regulation of signal transduction involved in conjugation with cellular fusion	biological_process	Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion.
GO:0060239	positive regulation of signal transduction involved in conjugation with cellular fusion	biological_process	Any process that increases the rate, frequency or extent of signal transduction involved in conjugation with cellular fusion.
GO:0060240	negative regulation of signal transduction involved in conjugation with cellular fusion	biological_process	Any process that decreases the rate, frequency or extent of the series signal transduction involved in conjugation with cellular fusion.
GO:0060241	lysozyme inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of lysozyme.
GO:0060242	contact inhibition	biological_process	The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.
GO:0060243	negative regulation of cell growth involved in contact inhibition	biological_process	The negative regulation of cell growth in response to increased cell density.
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	biological_process	Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.
GO:0060245	detection of cell density	biological_process	The series of events in which information about the density of cells in a population is received and converted into a molecular signal.
GO:0060249	anatomical structure homeostasis	biological_process	A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0060250	germ-line stem-cell niche homeostasis	biological_process	A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.
GO:0060251	regulation of glial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of glial cell proliferation.
GO:0060252	positive regulation of glial cell proliferation	biological_process	Any process that activates or increases the rate or extent of glial cell proliferation.
GO:0060253	negative regulation of glial cell proliferation	biological_process	Any process that stops or decreases the rate or extent of glial cell proliferation.
GO:0060254	regulation of N-terminal protein palmitoylation	biological_process	Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
GO:0060255	regulation of macromolecule metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0060256	regulation of flocculation	biological_process	Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.
GO:0060257	negative regulation of flocculation	biological_process	Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.
GO:0060258	negative regulation of filamentous growth	biological_process	Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
GO:0060259	regulation of feeding behavior	biological_process	Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
GO:0060260	regulation of transcription initiation by RNA polymerase II	biological_process	Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
GO:0060261	positive regulation of transcription initiation by RNA polymerase II	biological_process	Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
GO:0060262	negative regulation of N-terminal protein palmitoylation	biological_process	Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
GO:0060263	regulation of respiratory burst	biological_process	Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060264	regulation of respiratory burst involved in inflammatory response	biological_process	Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060265	positive regulation of respiratory burst involved in inflammatory response	biological_process	Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	biological_process	Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060267	positive regulation of respiratory burst	biological_process	Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060268	negative regulation of respiratory burst	biological_process	Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
GO:0060269	centripetally migrating follicle cell migration	biological_process	The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.
GO:0060270	main body follicle cell migration	biological_process	The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.
GO:0060271	cilium assembly	biological_process	The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0060272	embryonic skeletal joint morphogenesis	biological_process	The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.
GO:0060273	crying behavior	biological_process	The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
GO:0060274	maintenance of stationary phase	biological_process	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment.
GO:0060275	maintenance of stationary phase in response to starvation	biological_process	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.
GO:0060276	maintenance of stationary phase in response to toxin	biological_process	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment.
GO:0060278	regulation of ovulation	biological_process	Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GO:0060279	positive regulation of ovulation	biological_process	Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GO:0060280	negative regulation of ovulation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
GO:0060281	regulation of oocyte development	biological_process	Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0060282	positive regulation of oocyte development	biological_process	Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0060283	negative regulation of oocyte development	biological_process	Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
GO:0060284	regulation of cell development	biological_process	Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060285	cilium-dependent cell motility	biological_process	Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	biological_process	The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.
GO:0060288	formation of a compartment boundary	biological_process	Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
GO:0060289	compartment boundary maintenance	biological_process	A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
GO:0060290	transdifferentiation	biological_process	The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.
GO:0060291	long-term synaptic potentiation	biological_process	A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
GO:0060292	long-term synaptic depression	biological_process	A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
GO:0060293	germ plasm	cellular_component	Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.
GO:0060294	cilium movement involved in cell motility	biological_process	Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
GO:0060295	regulation of cilium movement involved in cell motility	biological_process	Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	biological_process	Any process that modulates the frequency of cilium beating involved in ciliary motility.
GO:0060297	regulation of sarcomere organization	biological_process	Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
GO:0060298	positive regulation of sarcomere organization	biological_process	Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
GO:0060299	negative regulation of sarcomere organization	biological_process	Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
GO:0060300	regulation of cytokine activity	biological_process	Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
GO:0060301	positive regulation of cytokine activity	biological_process	Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
GO:0060302	negative regulation of cytokine activity	biological_process	Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
GO:0060304	regulation of phosphatidylinositol dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
GO:0060305	regulation of cell diameter	biological_process	Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.
GO:0060306	regulation of membrane repolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
GO:0060308	GTP cyclohydrolase I regulator activity	molecular_function	Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
GO:0060309	elastin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
GO:0060310	regulation of elastin catabolic process	biological_process	Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
GO:0060311	negative regulation of elastin catabolic process	biological_process	Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
GO:0060312	regulation of blood vessel remodeling	biological_process	Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
GO:0060313	negative regulation of blood vessel remodeling	biological_process	Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	biological_process	Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	biological_process	Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	biological_process	Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
GO:0060317	cardiac epithelial to mesenchymal transition	biological_process	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0060318	definitive erythrocyte differentiation	biological_process	Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.
GO:0060319	primitive erythrocyte differentiation	biological_process	Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
GO:0060320	rejection of self pollen	biological_process	The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.
GO:0060321	acceptance of pollen	biological_process	The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.
GO:0060322	head development	biological_process	The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
GO:0060323	head morphogenesis	biological_process	The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
GO:0060324	face development	biological_process	The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.
GO:0060325	face morphogenesis	biological_process	The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
GO:0060326	cell chemotaxis	biological_process	The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0060327	cytoplasmic actin-based contraction involved in cell motility	biological_process	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
GO:0060328	cytoplasmic actin-based contraction involved in forward cell motility	biological_process	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.
GO:0060329	cytoplasmic actin-based contraction involved in rearward cell motility	biological_process	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.
GO:0060330	regulation of response to type II interferon	biological_process	Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
GO:0060331	negative regulation of response to type II interferon	biological_process	Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
GO:0060332	positive regulation of response to type II interferon	biological_process	Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
GO:0060333	type II interferon-mediated signaling pathway	biological_process	The series of molecular signals initiated by interferon-gamma binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
GO:0060334	regulation of type II interferon-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
GO:0060335	positive regulation of type II interferon-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
GO:0060336	negative regulation of type II interferon-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
GO:0060337	type I interferon-mediated signaling pathway	biological_process	The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0060338	regulation of type I interferon-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway.
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
GO:0060341	regulation of cellular localization	biological_process	Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
GO:0060342	photoreceptor inner segment membrane	cellular_component	The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
GO:0060343	trabecula formation	biological_process	The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
GO:0060344	liver trabecula formation	biological_process	The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.
GO:0060345	spleen trabecula formation	biological_process	The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.
GO:0060346	bone trabecula formation	biological_process	The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
GO:0060347	heart trabecula formation	biological_process	The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.
GO:0060348	bone development	biological_process	The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
GO:0060349	bone morphogenesis	biological_process	The process in which bones are generated and organized.
GO:0060350	endochondral bone morphogenesis	biological_process	The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.
GO:0060351	cartilage development involved in endochondral bone morphogenesis	biological_process	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.
GO:0060352	cell adhesion molecule production	biological_process	The appearance of a cell adhesion molecule due to biosynthesis or secretion.
GO:0060353	regulation of cell adhesion molecule production	biological_process	Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
GO:0060354	negative regulation of cell adhesion molecule production	biological_process	Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
GO:0060355	positive regulation of cell adhesion molecule production	biological_process	Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
GO:0060357	regulation of leucine import	biological_process	Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.
GO:0060358	negative regulation of leucine import	biological_process	Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.
GO:0060359	response to ammonium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.
GO:0060360	negative regulation of leucine import in response to ammonium ion	biological_process	Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.
GO:0060361	flight	biological_process	Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
GO:0060362	flight involved in flight behavior	biological_process	Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.
GO:0060363	cranial suture morphogenesis	biological_process	The process in which any suture between cranial bones is generated and organized.
GO:0060364	frontal suture morphogenesis	biological_process	The process in which the frontal suture is generated and organized.
GO:0060365	coronal suture morphogenesis	biological_process	The process in which the coronal suture is generated and organized.
GO:0060366	lambdoid suture morphogenesis	biological_process	The process in which the lambdoid suture is generated and organized.
GO:0060367	sagittal suture morphogenesis	biological_process	The process in which the sagittal suture is generated and organized.
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway..
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	biological_process	Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.
GO:0060370	susceptibility to T cell mediated cytotoxicity	biological_process	The process of causing a cell to become susceptible to T cell mediated cytotoxicity.
GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.
GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.
GO:0060374	mast cell differentiation	biological_process	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
GO:0060375	regulation of mast cell differentiation	biological_process	Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
GO:0060376	positive regulation of mast cell differentiation	biological_process	Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
GO:0060377	negative regulation of mast cell differentiation	biological_process	Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
GO:0060378	regulation of brood size	biological_process	Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
GO:0060379	cardiac muscle cell myoblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
GO:0060380	regulation of single-stranded telomeric DNA binding	biological_process	Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.
GO:0060381	positive regulation of single-stranded telomeric DNA binding	biological_process	Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.
GO:0060382	regulation of DNA strand elongation	biological_process	Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
GO:0060383	positive regulation of DNA strand elongation	biological_process	Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
GO:0060384	innervation	biological_process	The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
GO:0060385	axonogenesis involved in innervation	biological_process	The neurite development process that generates a long process of a neuron, as it invades a target tissue.
GO:0060386	synapse assembly involved in innervation	biological_process	The assembly of a synapse within a target tissue in which a nerve is invading.
GO:0060387	fertilization envelope	cellular_component	A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.
GO:0060388	vitelline envelope	cellular_component	A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.
GO:0060390	regulation of SMAD protein signal transduction	biological_process	Any process that modulates the rate, frequency or extent of SMAD protein signal transduction.
GO:0060391	positive regulation of SMAD protein signal transduction	biological_process	Any process that increases the rate, frequency or extent of SMAD protein signal transduction.
GO:0060392	negative regulation of SMAD protein signal transduction	biological_process	Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway.
GO:0060395	SMAD protein signal transduction	biological_process	An intracellular signal transduction pathway that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus, where it regulates transcription of specific target genes.
GO:0060396	growth hormone receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
GO:0060397	growth hormone receptor signaling pathway via JAK-STAT	biological_process	The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
GO:0060398	regulation of growth hormone receptor signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
GO:0060399	positive regulation of growth hormone receptor signaling pathway	biological_process	Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
GO:0060400	negative regulation of growth hormone receptor signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
GO:0060402	calcium ion transport into cytosol	biological_process	The directed movement of calcium ions (Ca2+) into the cytosol.
GO:0060404	axonemal microtubule depolymerization	biological_process	The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
GO:0060405	regulation of penile erection	biological_process	Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
GO:0060406	positive regulation of penile erection	biological_process	Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
GO:0060407	negative regulation of penile erection	biological_process	Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
GO:0060408	regulation of acetylcholine metabolic process	biological_process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
GO:0060409	positive regulation of acetylcholine metabolic process	biological_process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
GO:0060410	negative regulation of acetylcholine metabolic process	biological_process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
GO:0060411	cardiac septum morphogenesis	biological_process	The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.
GO:0060412	ventricular septum morphogenesis	biological_process	The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
GO:0060413	atrial septum morphogenesis	biological_process	The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
GO:0060414	aorta smooth muscle tissue morphogenesis	biological_process	The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
GO:0060415	muscle tissue morphogenesis	biological_process	The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.
GO:0060416	response to growth hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
GO:0060417	yolk	cellular_component	The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.
GO:0060418	yolk plasma	cellular_component	Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.
GO:0060419	heart growth	biological_process	The increase in size or mass of the heart.
GO:0060420	regulation of heart growth	biological_process	Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
GO:0060421	positive regulation of heart growth	biological_process	Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
GO:0060422	peptidyl-dipeptidase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.
GO:0060423	foregut regionalization	biological_process	The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.
GO:0060424	lung field specification	biological_process	The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.
GO:0060425	lung morphogenesis	biological_process	The process in which the anatomical structures of the lung are generated and organized.
GO:0060426	lung vasculature development	biological_process	The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.
GO:0060427	lung connective tissue development	biological_process	The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.
GO:0060428	lung epithelium development	biological_process	The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
GO:0060429	epithelium development	biological_process	The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
GO:0060430	lung saccule development	biological_process	The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.
GO:0060431	primary lung bud formation	biological_process	The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.
GO:0060432	lung pattern specification process	biological_process	Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.
GO:0060433	bronchus development	biological_process	The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.
GO:0060434	bronchus morphogenesis	biological_process	The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.
GO:0060435	bronchiole development	biological_process	The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
GO:0060436	bronchiole morphogenesis	biological_process	The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
GO:0060437	lung growth	biological_process	The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
GO:0060438	trachea development	biological_process	The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.
GO:0060439	trachea morphogenesis	biological_process	The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
GO:0060440	trachea formation	biological_process	The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.
GO:0060441	epithelial tube branching involved in lung morphogenesis	biological_process	The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
GO:0060442	branching involved in prostate gland morphogenesis	biological_process	The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.
GO:0060443	mammary gland morphogenesis	biological_process	The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
GO:0060444	branching involved in mammary gland duct morphogenesis	biological_process	The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
GO:0060445	branching involved in salivary gland morphogenesis	biological_process	The process in which the branching structure of the salivary gland is generated and organized.
GO:0060446	branching involved in open tracheal system development	biological_process	The process in which the anatomical structures of branches in the open tracheal system are generated and organized.
GO:0060447	bud outgrowth involved in lung branching	biological_process	The process in which a region of the lung epithelium initiates an outgrowth.
GO:0060448	dichotomous subdivision of terminal units involved in lung branching	biological_process	The process in which a lung bud bifurcates.
GO:0060449	bud elongation involved in lung branching	biological_process	The process in which a bud in the lung grows out from the point where it is formed.
GO:0060450	positive regulation of hindgut contraction	biological_process	Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
GO:0060451	negative regulation of hindgut contraction	biological_process	Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
GO:0060452	positive regulation of cardiac muscle contraction	biological_process	Any process that increases the frequency, rate or extent of cardiac muscle contraction.
GO:0060453	regulation of gastric acid secretion	biological_process	Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
GO:0060454	positive regulation of gastric acid secretion	biological_process	Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
GO:0060455	negative regulation of gastric acid secretion	biological_process	Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
GO:0060456	positive regulation of digestive system process	biological_process	Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0060457	negative regulation of digestive system process	biological_process	Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
GO:0060458	right lung development	biological_process	The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.
GO:0060459	left lung development	biological_process	The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.
GO:0060460	left lung morphogenesis	biological_process	The process in which anatomical structures of the left lung are generated and organized.
GO:0060461	right lung morphogenesis	biological_process	The process in which anatomical structures of the right lung are generated and organized.
GO:0060462	lung lobe development	biological_process	The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.
GO:0060463	lung lobe morphogenesis	biological_process	The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.
GO:0060464	lung lobe formation	biological_process	The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.
GO:0060465	pharynx development	biological_process	The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
GO:0060466	activation of meiosis involved in egg activation	biological_process	Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.
GO:0060467	negative regulation of fertilization	biological_process	Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GO:0060468	prevention of polyspermy	biological_process	The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.
GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	biological_process	The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.
GO:0060471	cortical granule exocytosis	biological_process	The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
GO:0060472	positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration	biological_process	Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.
GO:0060473	cortical granule	cellular_component	A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
GO:0060474	positive regulation of flagellated sperm motility involved in capacitation	biological_process	The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
GO:0060476	protein localization involved in acrosome reaction	biological_process	The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.
GO:0060478	acrosomal vesicle exocytosis	biological_process	The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.
GO:0060479	lung cell differentiation	biological_process	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
GO:0060480	lung goblet cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.
GO:0060481	lobar bronchus epithelium development	biological_process	The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.
GO:0060482	lobar bronchus development	biological_process	The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.
GO:0060483	lobar bronchus mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.
GO:0060484	lung-associated mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.
GO:0060485	mesenchyme development	biological_process	The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.
GO:0060486	club cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
GO:0060487	lung epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	biological_process	The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	biological_process	The process in which a lung bud bifurcates parallel to the plane of the previous bud.
GO:0060490	lateral sprouting involved in lung morphogenesis	biological_process	The process in which a branch forms along the side of the lung epithelial tube.
GO:0060491	regulation of cell projection assembly	biological_process	Any process that modulates the rate, frequency, or extent of cell projection assembly.
GO:0060492	lung induction	biological_process	The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.
GO:0060493	mesenchymal-endodermal cell signaling involved in lung induction	biological_process	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.
GO:0060494	inductive mesenchymal-endodermal cell signaling	biological_process	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.
GO:0060495	cell-cell signaling involved in lung development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.
GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	biological_process	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.
GO:0060497	mesenchymal-endodermal cell signaling	biological_process	Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.
GO:0060498	retinoic acid receptor signaling pathway involved in lung bud formation	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.
GO:0060499	fibroblast growth factor receptor signaling pathway involved in lung induction	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	biological_process	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	biological_process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.
GO:0060503	bud dilation involved in lung branching	biological_process	The process in which a bud in the lung increases radially.
GO:0060504	positive regulation of epithelial cell proliferation involved in lung bud dilation	biological_process	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.
GO:0060505	epithelial cell proliferation involved in lung bud dilation	biological_process	The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.
GO:0060506	smoothened signaling pathway involved in lung development	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.
GO:0060507	epidermal growth factor receptor signaling pathway involved in lung development	biological_process	The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.
GO:0060508	lung basal cell differentiation	biological_process	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.
GO:0060509	type I pneumocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
GO:0060510	type II pneumocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
GO:0060512	prostate gland morphogenesis	biological_process	The process in which the anatomical structures of a prostate gland are generated and organized.
GO:0060513	prostatic bud formation	biological_process	The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
GO:0060514	prostate induction	biological_process	The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.
GO:0060515	prostate field specification	biological_process	The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.
GO:0060516	primary prostatic bud elongation	biological_process	The increase in size of the prostatic bud as it forms.
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	biological_process	The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.
GO:0060518	cell migration involved in prostatic bud elongation	biological_process	The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.
GO:0060519	cell adhesion involved in prostatic bud elongation	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	biological_process	The series of molecular signals initiated by androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.
GO:0060521	mesenchymal-epithelial cell signaling involved in prostate induction	biological_process	Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.
GO:0060522	inductive mesenchymal to epithelial cell signaling	biological_process	Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.
GO:0060523	prostate epithelial cord elongation	biological_process	The developmental growth process in which solid chords of prostate epithelium increase in length.
GO:0060524	dichotomous subdivision of prostate epithelial cord terminal unit	biological_process	The process in which a prostate epithelial cord bifurcates at its end.
GO:0060525	prostate glandular acinus development	biological_process	The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.
GO:0060526	prostate glandular acinus morphogenesis	biological_process	The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	biological_process	The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	biological_process	The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	biological_process	The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.
GO:0060530	smooth muscle cell differentiation involved in prostate glandular acinus development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.
GO:0060531	neuroendocrine cell differentiation involved in prostate gland acinus development	biological_process	The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.
GO:0060532	bronchus cartilage development	biological_process	The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0060533	bronchus cartilage morphogenesis	biological_process	The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.
GO:0060534	trachea cartilage development	biological_process	The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0060535	trachea cartilage morphogenesis	biological_process	The process in which the anatomical structures of cartilage in the trachea are generated and organized.
GO:0060536	cartilage morphogenesis	biological_process	The process in which the anatomical structures of cartilage are generated and organized.
GO:0060537	muscle tissue development	biological_process	The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.
GO:0060538	skeletal muscle organ development	biological_process	The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.
GO:0060539	diaphragm development	biological_process	The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.
GO:0060540	diaphragm morphogenesis	biological_process	The process in which the anatomical structures of the diaphragm are generated and organized.
GO:0060541	respiratory system development	biological_process	The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.
GO:0060542	regulation of strand invasion	biological_process	Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
GO:0060543	negative regulation of strand invasion	biological_process	Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
GO:0060544	regulation of necroptotic process	biological_process	Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
GO:0060545	positive regulation of necroptotic process	biological_process	Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
GO:0060546	negative regulation of necroptotic process	biological_process	Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
GO:0060549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity	biological_process	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
GO:0060550	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity	biological_process	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
GO:0060551	regulation of fructose 1,6-bisphosphate metabolic process	biological_process	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process	biological_process	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
GO:0060556	regulation of vitamin D biosynthetic process	biological_process	Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0060557	positive regulation of vitamin D biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
GO:0060558	regulation of calcidiol 1-monooxygenase activity	biological_process	Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	biological_process	Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
GO:0060560	developmental growth involved in morphogenesis	biological_process	The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.
GO:0060561	apoptotic process involved in morphogenesis	biological_process	Any apoptotic process that contributes to the shaping of an anatomical structure.
GO:0060562	epithelial tube morphogenesis	biological_process	The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
GO:0060563	neuroepithelial cell differentiation	biological_process	The process in which epiblast cells acquire specialized features of neuroepithelial cells.
GO:0060566	positive regulation of termination of DNA-templated transcription	biological_process	Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
GO:0060567	negative regulation of termination of DNA-templated transcription	biological_process	Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
GO:0060568	regulation of peptide hormone processing	biological_process	Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
GO:0060569	positive regulation of peptide hormone processing	biological_process	Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
GO:0060570	negative regulation of peptide hormone processing	biological_process	Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
GO:0060571	morphogenesis of an epithelial fold	biological_process	The morphogenetic process in which an epithelial sheet bends along a linear axis.
GO:0060572	morphogenesis of an epithelial bud	biological_process	The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.
GO:0060573	cell fate specification involved in pattern specification	biological_process	The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.
GO:0060574	intestinal epithelial cell maturation	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.
GO:0060575	intestinal epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.
GO:0060576	intestinal epithelial cell development	biological_process	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.
GO:0060577	pulmonary vein morphogenesis	biological_process	The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.
GO:0060578	superior vena cava morphogenesis	biological_process	The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.
GO:0060579	ventral spinal cord interneuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
GO:0060580	ventral spinal cord interneuron fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
GO:0060581	cell fate commitment involved in pattern specification	biological_process	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.
GO:0060582	cell fate determination involved in pattern specification	biological_process	A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
GO:0060583	regulation of actin cortical patch localization	biological_process	Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
GO:0060584	regulation of prostaglandin-endoperoxide synthase activity	biological_process	Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	biological_process	Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
GO:0060586	multicellular organismal-level iron ion homeostasis	biological_process	A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
GO:0060587	regulation of lipoprotein lipid oxidation	biological_process	Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.
GO:0060588	negative regulation of lipoprotein lipid oxidation	biological_process	Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.
GO:0060589	nucleoside-triphosphatase regulator activity	molecular_function	Binds to and modulates the activity of an NTPase.
GO:0060590	ATPase regulator activity	molecular_function	Binds to and modulates the activity of an ATP hydrolysis activity.
GO:0060591	chondroblast differentiation	biological_process	The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.
GO:0060592	mammary gland formation	biological_process	The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.
GO:0060593	Wnt signaling pathway involved in mammary gland specification	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
GO:0060594	mammary gland specification	biological_process	The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	biological_process	The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
GO:0060596	mammary placode formation	biological_process	The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.
GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	biological_process	The process in which the terminal end of a mammary duct bifurcates.
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	biological_process	The process in which a branch forms along the side of a mammary duct.
GO:0060600	dichotomous subdivision of an epithelial terminal unit	biological_process	The process in which an epithelial cord, rod or tube bifurcates at its end.
GO:0060601	lateral sprouting from an epithelium	biological_process	The process in which a branch forms along the side of an epithelium.
GO:0060602	branch elongation of an epithelium	biological_process	The growth process in which a branch increases in length from its base to its tip.
GO:0060603	mammary gland duct morphogenesis	biological_process	The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
GO:0060604	mammary gland duct cavitation	biological_process	Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.
GO:0060605	tube lumen cavitation	biological_process	The formation of a lumen by hollowing out a solid rod or cord.
GO:0060606	tube closure	biological_process	Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.
GO:0060607	cell-cell adhesion involved in sealing an epithelial fold	biological_process	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.
GO:0060608	cell-cell adhesion involved in neural tube closure	biological_process	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.
GO:0060609	apoptotic process involved in tube lumen cavitation	biological_process	Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.
GO:0060610	mesenchymal cell differentiation involved in mammary gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.
GO:0060611	mammary gland fat development	biological_process	The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.
GO:0060612	adipose tissue development	biological_process	The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.
GO:0060613	fat pad development	biological_process	The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.
GO:0060614	negative regulation of mammary gland development in males by androgen receptor signaling pathway	biological_process	Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.
GO:0060615	mammary gland bud formation	biological_process	The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.
GO:0060616	mammary gland cord formation	biological_process	The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.
GO:0060617	positive regulation of mammary placode formation by mesenchymal-epithelial signaling	biological_process	Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.
GO:0060618	nipple development	biological_process	The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.
GO:0060619	cell migration involved in mammary placode formation	biological_process	The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.
GO:0060620	regulation of cholesterol import	biological_process	Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.
GO:0060621	negative regulation of cholesterol import	biological_process	Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.
GO:0060622	regulation of ascospore wall beta-glucan biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
GO:0060623	regulation of chromosome condensation	biological_process	Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
GO:0060624	regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.
GO:0060625	regulation of protein deneddylation	biological_process	Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.
GO:0060627	regulation of vesicle-mediated transport	biological_process	Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	biological_process	Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
GO:0060629	regulation of homologous chromosome segregation	biological_process	Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
GO:0060631	regulation of meiosis I	biological_process	Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
GO:0060632	regulation of microtubule-based movement	biological_process	Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
GO:0060633	negative regulation of transcription initiation by RNA polymerase II	biological_process	Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
GO:0060634	regulation of 4,6-pyruvylated galactose residue biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.
GO:0060635	positive regulation of (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
GO:0060636	negative regulation of (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
GO:0060637	positive regulation of lactation by mesenchymal-epithelial cell signaling	biological_process	The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.
GO:0060638	mesenchymal-epithelial cell signaling	biological_process	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.
GO:0060639	positive regulation of salivary gland formation by mesenchymal-epithelial signaling	biological_process	Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.
GO:0060640	positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling	biological_process	Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.
GO:0060641	mammary gland duct regression in males	biological_process	The process in which the epithelium of the mammary duct is destroyed in males.
GO:0060642	white fat cell differentiation involved in mammary gland fat development	biological_process	The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
GO:0060643	epithelial cell differentiation involved in mammary gland bud morphogenesis	biological_process	The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.
GO:0060644	mammary gland epithelial cell differentiation	biological_process	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.
GO:0060645	peripheral mammary gland bud epithelial cell differentiation	biological_process	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.
GO:0060646	internal mammary gland bud epithelial cell differentiation	biological_process	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.
GO:0060647	mesenchymal cell condensation involved in mammary fat development	biological_process	The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.
GO:0060648	mammary gland bud morphogenesis	biological_process	The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.
GO:0060649	mammary gland bud elongation	biological_process	The process in which the mammary gland bud grows along its axis.
GO:0060650	epithelial cell proliferation involved in mammary gland bud elongation	biological_process	The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.
GO:0060651	regulation of epithelial cell proliferation involved in mammary gland bud elongation	biological_process	Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.
GO:0060652	mammary gland cord morphogenesis	biological_process	The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.
GO:0060653	epithelial cell differentiation involved in mammary gland cord morphogenesis	biological_process	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.
GO:0060654	mammary gland cord elongation	biological_process	The process in which the mammary gland sprout grows along its axis.
GO:0060655	branching involved in mammary gland cord morphogenesis	biological_process	The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.
GO:0060656	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling	biological_process	Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.
GO:0060657	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling	biological_process	Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.
GO:0060658	nipple morphogenesis	biological_process	The process in which the nipple is generated and organized.
GO:0060659	nipple sheath formation	biological_process	The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.
GO:0060660	epidermis morphogenesis involved in nipple formation	biological_process	The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.
GO:0060661	submandibular salivary gland formation	biological_process	The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.
GO:0060662	salivary gland cavitation	biological_process	The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.
GO:0060663	apoptotic process involved in salivary gland cavitation	biological_process	Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	biological_process	The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	biological_process	Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	biological_process	The process in which a salivary epithelial cord bifurcates at its end.
GO:0060667	branch elongation involved in salivary gland morphogenesis	biological_process	The differential growth of the salivary branches along their axis, resulting in the growth of a branch.
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	biological_process	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.
GO:0060669	embryonic placenta morphogenesis	biological_process	The process in which the embryonic placenta is generated and organized.
GO:0060670	branching involved in labyrinthine layer morphogenesis	biological_process	The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.
GO:0060671	epithelial cell differentiation involved in embryonic placenta development	biological_process	The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.
GO:0060672	epithelial cell morphogenesis involved in placental branching	biological_process	The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.
GO:0060673	cell-cell signaling involved in placenta development	biological_process	Any process that mediates the transfer of information from one cell to another.
GO:0060674	placenta blood vessel development	biological_process	The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.
GO:0060675	ureteric bud morphogenesis	biological_process	The process in which the ureteric bud is generated and organized.
GO:0060676	ureteric bud formation	biological_process	The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.
GO:0060677	ureteric bud elongation	biological_process	The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	biological_process	The process in which a ureteric bud bifurcates at its end.
GO:0060679	trifid subdivision of terminal units involved in ureteric bud branching	biological_process	The process in which a ureteric bud splits into three units at its end.
GO:0060680	lateral sprouting involved in ureteric bud morphogenesis	biological_process	The process in which a branch forms along the side of a ureteric bud.
GO:0060681	branch elongation involved in ureteric bud branching	biological_process	The growth of a branch of the ureteric bud along its axis.
GO:0060682	primary ureteric bud growth	biological_process	The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	biological_process	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.
GO:0060684	epithelial-mesenchymal cell signaling	biological_process	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.
GO:0060685	regulation of prostatic bud formation	biological_process	Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
GO:0060686	negative regulation of prostatic bud formation	biological_process	Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
GO:0060687	regulation of branching involved in prostate gland morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.
GO:0060688	regulation of morphogenesis of a branching structure	biological_process	Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.
GO:0060689	cell differentiation involved in salivary gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.
GO:0060690	epithelial cell differentiation involved in salivary gland development	biological_process	The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.
GO:0060691	epithelial cell maturation involved in salivary gland development	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.
GO:0060692	mesenchymal cell differentiation involved in salivary gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
GO:0060693	regulation of branching involved in salivary gland morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.
GO:0060694	regulation of cholesterol transporter activity	biological_process	Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.
GO:0060695	negative regulation of cholesterol transporter activity	biological_process	Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.
GO:0060696	regulation of phospholipid catabolic process	biological_process	Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0060697	positive regulation of phospholipid catabolic process	biological_process	Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
GO:0060698	endoribonuclease inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of endoribonuclease.
GO:0060699	regulation of endoribonuclease activity	biological_process	Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0060700	regulation of ribonuclease activity	biological_process	Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0060701	negative regulation of ribonuclease activity	biological_process	Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
GO:0060702	negative regulation of endoribonuclease activity	biological_process	Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
GO:0060703	deoxyribonuclease inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of deoxyribonuclease.
GO:0060704	acinar cell differentiation involved in salivary gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.
GO:0060705	neuron differentiation involved in salivary gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.
GO:0060706	cell differentiation involved in embryonic placenta development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.
GO:0060707	trophoblast giant cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.
GO:0060708	spongiotrophoblast differentiation	biological_process	The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.
GO:0060709	glycogen cell differentiation involved in embryonic placenta development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.
GO:0060710	chorio-allantoic fusion	biological_process	The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.
GO:0060711	labyrinthine layer development	biological_process	The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.
GO:0060712	spongiotrophoblast layer development	biological_process	The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.
GO:0060713	labyrinthine layer morphogenesis	biological_process	The process in which the labyrinthine layer of the placenta is generated and organized.
GO:0060714	labyrinthine layer formation	biological_process	The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.
GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	biological_process	The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.
GO:0060716	labyrinthine layer blood vessel development	biological_process	The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.
GO:0060717	chorion development	biological_process	The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.
GO:0060718	chorionic trophoblast cell differentiation	biological_process	The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
GO:0060719	chorionic trophoblast cell development	biological_process	The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GO:0060720	spongiotrophoblast cell proliferation	biological_process	The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.
GO:0060721	regulation of spongiotrophoblast cell proliferation	biological_process	Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.
GO:0060722	cell proliferation involved in embryonic placenta development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.
GO:0060723	regulation of cell proliferation involved in embryonic placenta development	biological_process	Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.
GO:0060725	regulation of coreceptor activity	biological_process	Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
GO:0060729	intestinal epithelial structure maintenance	biological_process	A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
GO:0060730	regulation of intestinal epithelial structure maintenance	biological_process	Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
GO:0060731	positive regulation of intestinal epithelial structure maintenance	biological_process	Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
GO:0060732	positive regulation of inositol phosphate biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	biological_process	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.
GO:0060735	regulation of eIF2 alpha phosphorylation by dsRNA	biological_process	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.
GO:0060736	prostate gland growth	biological_process	The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.
GO:0060737	prostate gland morphogenetic growth	biological_process	The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	biological_process	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	biological_process	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.
GO:0060740	prostate gland epithelium morphogenesis	biological_process	The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
GO:0060741	prostate gland stromal morphogenesis	biological_process	The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.
GO:0060742	epithelial cell differentiation involved in prostate gland development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.
GO:0060743	epithelial cell maturation involved in prostate gland development	biological_process	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
GO:0060744	mammary gland branching involved in thelarche	biological_process	The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
GO:0060745	mammary gland branching involved in pregnancy	biological_process	The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.
GO:0060746	parental behavior	biological_process	A reproductive behavior in which a parent cares for and rears offspring.
GO:0060747	oral incubation	biological_process	A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.
GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	biological_process	The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.
GO:0060749	mammary gland alveolus development	biological_process	The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	biological_process	The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.
GO:0060751	branch elongation involved in mammary gland duct branching	biological_process	The developmental growth process in which a branch of a mammary gland duct elongates.
GO:0060752	intestinal phytosterol absorption	biological_process	Any process in which phytosterols are taken up from the contents of the intestine.
GO:0060753	regulation of mast cell chemotaxis	biological_process	Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
GO:0060754	positive regulation of mast cell chemotaxis	biological_process	Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
GO:0060755	negative regulation of mast cell chemotaxis	biological_process	Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
GO:0060756	foraging behavior	biological_process	Behavior by which an organism locates food.
GO:0060757	adult foraging behavior	biological_process	Behavior by which an adult locates food.
GO:0060758	foraging behavior by probing substrate	biological_process	Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.
GO:0060759	regulation of response to cytokine stimulus	biological_process	Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.
GO:0060760	positive regulation of response to cytokine stimulus	biological_process	Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.
GO:0060761	negative regulation of response to cytokine stimulus	biological_process	Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.
GO:0060763	mammary duct terminal end bud growth	biological_process	The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.
GO:0060764	cell-cell signaling involved in mammary gland development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.
GO:0060765	regulation of androgen receptor signaling pathway	biological_process	Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
GO:0060766	negative regulation of androgen receptor signaling pathway	biological_process	Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.
GO:0060767	epithelial cell proliferation involved in prostate gland development	biological_process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	biological_process	Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	biological_process	Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	biological_process	Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
GO:0060771	phyllotactic patterning	biological_process	The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.
GO:0060772	leaf phyllotactic patterning	biological_process	The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.
GO:0060773	flower phyllotactic patterning	biological_process	The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.
GO:0060774	auxin mediated signaling pathway involved in phyllotactic patterning	biological_process	The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.
GO:0060775	planar cell polarity pathway involved in gastrula mediolateral intercalation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.
GO:0060776	simple leaf morphogenesis	biological_process	The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.
GO:0060777	compound leaf morphogenesis	biological_process	The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.
GO:0060778	primary leaflet morphogenesis	biological_process	The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.
GO:0060779	secondary leaflet morphogenesis	biological_process	The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.
GO:0060780	intercalary leaflet morphogenesis	biological_process	The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.
GO:0060781	mesenchymal cell proliferation involved in prostate gland development	biological_process	The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.
GO:0060785	regulation of apoptosis involved in tissue homeostasis	biological_process	Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.
GO:0060786	regulation of cell differentiation involved in tissue homeostasis	biological_process	Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.
GO:0060787	positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway	biological_process	Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
GO:0060788	ectodermal placode formation	biological_process	The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
GO:0060789	hair follicle placode formation	biological_process	The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
GO:0060790	tooth placode formation	biological_process	The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.
GO:0060791	sebaceous gland placode formation	biological_process	The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.
GO:0060792	sweat gland development	biological_process	The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.
GO:0060793	sweat gland placode formation	biological_process	The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.
GO:0060794	leaflet morphogenesis	biological_process	The process in which the anatomical structures of the leaflet are generated and organized.
GO:0060795	cell fate commitment involved in formation of primary germ layer	biological_process	The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.
GO:0060800	regulation of cell differentiation involved in embryonic placenta development	biological_process	Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.
GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	biological_process	Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	biological_process	Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.
GO:0060808	positive regulation of mesodermal to mesenchymal transition involved in gastrulation	biological_process	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	biological_process	The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.
GO:0060810	intracellular mRNA localization involved in pattern specification process	biological_process	Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.
GO:0060811	intracellular mRNA localization involved in anterior/posterior axis specification	biological_process	Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.
GO:0060812	orthodenticle mRNA localization	biological_process	Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.
GO:0060813	anterior mRNA localization involved in anterior/posterior axis specification	biological_process	Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
GO:0060814	posterior mRNA localization involved in anterior/posterior axis specification	biological_process	Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
GO:0060815	regulation of translation involved in anterior/posterior axis specification	biological_process	Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.
GO:0060816	random inactivation of X chromosome	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.
GO:0060817	inactivation of paternal X chromosome	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.
GO:0060818	inactivation of paternal X chromosome by genomic imprinting	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting.
GO:0060819	inactivation of X chromosome by genomic imprinting	biological_process	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genomic imprinting.
GO:0060820	inactivation of X chromosome by heterochromatin formation	biological_process	Compensating for the two-fold variation in X-chromosome: autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
GO:0060823	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.
GO:0060824	retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.
GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.
GO:0060827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.
GO:0060828	regulation of canonical Wnt signaling pathway	biological_process	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	biological_process	Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	biological_process	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
GO:0060832	oocyte animal/vegetal axis specification	biological_process	The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.
GO:0060833	Wnt signaling pathway involved in animal/vegetal axis specification	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.
GO:0060834	oral/aboral axis specification	biological_process	The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.
GO:0060836	lymphatic endothelial cell differentiation	biological_process	The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.
GO:0060837	blood vessel endothelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.
GO:0060838	lymphatic endothelial cell fate commitment	biological_process	The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.
GO:0060839	endothelial cell fate commitment	biological_process	The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.
GO:0060840	artery development	biological_process	The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.
GO:0060841	venous blood vessel development	biological_process	The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.
GO:0060842	arterial endothelial cell differentiation	biological_process	The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.
GO:0060843	venous endothelial cell differentiation	biological_process	The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.
GO:0060844	arterial endothelial cell fate commitment	biological_process	The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.
GO:0060845	venous endothelial cell fate commitment	biological_process	The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.
GO:0060846	blood vessel endothelial cell fate commitment	biological_process	The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.
GO:0060847	endothelial cell fate specification	biological_process	The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
GO:0060848	endothelial cell fate determination	biological_process	A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
GO:0060851	vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment	biological_process	The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.
GO:0060853	Notch signaling pathway involved in arterial endothelial cell fate commitment	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.
GO:0060854	branching involved in lymph vessel morphogenesis	biological_process	The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.
GO:0060855	venous endothelial cell migration involved in lymph vessel development	biological_process	The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.
GO:0060856	establishment of blood-brain barrier	biological_process	Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
GO:0060857	establishment of glial blood-brain barrier	biological_process	Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
GO:0060858	vesicle-mediated transport involved in floral organ abscission	biological_process	The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.
GO:0060860	regulation of floral organ abscission	biological_process	Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.
GO:0060861	positive regulation of floral organ abscission	biological_process	Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.
GO:0060862	negative regulation of floral organ abscission	biological_process	Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.
GO:0060863	regulation of floral organ abscission by signal transduction	biological_process	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.
GO:0060865	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway	biological_process	The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.
GO:0060866	leaf abscission	biological_process	The controlled shedding of a leaf.
GO:0060867	fruit abscission	biological_process	The controlled shedding of a fruit.
GO:0060869	transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission	biological_process	The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.
GO:0060870	cell wall disassembly involved in floral organ abscission	biological_process	A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.
GO:0060872	semicircular canal development	biological_process	The progression of the semicircular canal from its initial formation to the mature structure.
GO:0060873	anterior semicircular canal development	biological_process	The progession of the anterior semicircular canal from its initial formation to the mature structure.
GO:0060874	posterior semicircular canal development	biological_process	The progession of the posterior semicircular canal from its initial formation to the mature structure.
GO:0060875	lateral semicircular canal development	biological_process	The progession of the lateral semicircular canal from its initial formation to the mature structure.
GO:0060876	semicircular canal formation	biological_process	The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.
GO:0060877	regionalization involved in semicircular canal formation	biological_process	The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.
GO:0060878	pouch outgrowth involved in semicircular canal formation	biological_process	The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.
GO:0060879	semicircular canal fusion	biological_process	Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.
GO:0060880	cell morphogenesis involved in semicircular canal fusion	biological_process	The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.
GO:0060882	basement membrane disassembly involved in semicircular canal fusion	biological_process	A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.
GO:0060884	clearance of cells from fusion plate	biological_process	The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.
GO:0060885	clearance of cells from fusion plate by apoptotic process	biological_process	Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.
GO:0060886	clearance of cells from fusion plate by epithelial to mesenchymal transition	biological_process	The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.
GO:0060887	limb epidermis development	biological_process	The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.
GO:0060888	limb epidermis stratification	biological_process	The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.
GO:0060889	limb basal epidermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.
GO:0060890	limb spinous cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.
GO:0060891	limb granular cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.
GO:0060892	limb basal epidermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0060893	limb granular cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0060894	limb spinous cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0060895	retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.
GO:0060896	neural plate pattern specification	biological_process	The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.
GO:0060897	neural plate regionalization	biological_process	The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
GO:0060898	eye field cell fate commitment involved in camera-type eye formation	biological_process	The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.
GO:0060900	embryonic camera-type eye formation	biological_process	The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.
GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.
GO:0060903	positive regulation of meiosis I	biological_process	Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
GO:0060904	regulation of protein folding in endoplasmic reticulum	biological_process	Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
GO:0060905	regulation of induction of conjugation upon nitrogen starvation	biological_process	Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.
GO:0060906	negative regulation of regulatory ncRNA-mediated heterochromatin formation	biological_process	Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation.
GO:0060907	positive regulation of macrophage cytokine production	biological_process	Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0060908	plasmid copy number maintenance	biological_process	The maintenance of the number of copies of extrachromosomal plasmid DNA.
GO:0060909	regulation of DNA replication initiation involved in plasmid copy number maintenance	biological_process	Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.
GO:0060910	negative regulation of DNA replication initiation involved in plasmid copy number maintenance	biological_process	Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.
GO:0060911	cardiac cell fate commitment	biological_process	The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.
GO:0060912	cardiac cell fate specification	biological_process	The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
GO:0060913	cardiac cell fate determination	biological_process	The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
GO:0060914	heart formation	biological_process	The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.
GO:0060915	mesenchymal cell differentiation involved in lung development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
GO:0060916	mesenchymal cell proliferation involved in lung development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0060917	regulation of (1->6)-beta-D-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
GO:0060918	auxin transport	biological_process	The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth.
GO:0060919	auxin import into cell	biological_process	The directed movement of auxins from outside of a cell into a cell.
GO:0060920	cardiac pacemaker cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
GO:0060921	sinoatrial node cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.
GO:0060922	atrioventricular node cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.
GO:0060923	cardiac muscle cell fate commitment	biological_process	The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
GO:0060924	atrial cardiac muscle cell fate commitment	biological_process	The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
GO:0060925	ventricular cardiac muscle cell fate commitment	biological_process	The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
GO:0060926	cardiac pacemaker cell development	biological_process	The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
GO:0060927	cardiac pacemaker cell fate commitment	biological_process	The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
GO:0060928	atrioventricular node cell development	biological_process	The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.
GO:0060929	atrioventricular node cell fate commitment	biological_process	The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.
GO:0060930	sinoatrial node cell fate commitment	biological_process	The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.
GO:0060931	sinoatrial node cell development	biological_process	The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.
GO:0060932	His-Purkinje system cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.
GO:0060933	His-Purkinje system cell development	biological_process	The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.
GO:0060934	His-Purkinje system cell fate commitment	biological_process	The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.
GO:0060935	cardiac fibroblast cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060936	cardiac fibroblast cell development	biological_process	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060937	cardiac fibroblast cell fate commitment	biological_process	The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060938	epicardium-derived cardiac fibroblast cell differentiation	biological_process	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060939	epicardium-derived cardiac fibroblast cell development	biological_process	The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development	biological_process	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.
GO:0060941	epicardium-derived cardiac fibroblast cell fate commitment	biological_process	The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060942	neural crest-derived cardiac fibroblast cell differentiation	biological_process	The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060943	neural crest-derived cardiac fibroblast cell development	biological_process	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060944	neural crest-derived cardiac fibroblast cell fate commitment	biological_process	The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
GO:0060945	cardiac neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.
GO:0060946	cardiac blood vessel endothelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.
GO:0060947	cardiac vascular smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
GO:0060948	cardiac vascular smooth muscle cell development	biological_process	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.
GO:0060949	cardiac vascular smooth muscle cell fate commitment	biological_process	The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.
GO:0060950	cardiac glial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.
GO:0060951	neural crest-derived cardiac glial cell differentiation	biological_process	The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.
GO:0060952	cardiac glial cell development	biological_process	The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.
GO:0060953	cardiac glial cell fate commitment	biological_process	The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.
GO:0060954	neural crest-derived cardiac glial cell development	biological_process	The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0060955	neural crest-derived cardiac glial cell fate commitment	biological_process	The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.
GO:0060956	endocardial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0060957	endocardial cell fate commitment	biological_process	The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.
GO:0060958	endocardial cell development	biological_process	The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.
GO:0060959	cardiac neuron development	biological_process	The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.
GO:0060960	cardiac neuron fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.
GO:0060961	phospholipase D inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of phospholipase D.
GO:0060962	regulation of ribosomal protein gene transcription by RNA polymerase II	biological_process	Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.
GO:0060963	positive regulation of ribosomal protein gene transcription by RNA polymerase II	biological_process	Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.
GO:0060964	regulation of miRNA-mediated gene silencing	biological_process	A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs).
GO:0060965	negative regulation of miRNA-mediated gene silencing	biological_process	A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA).
GO:0060966	regulation of gene silencing by regulatory ncRNA	biological_process	Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
GO:0060967	negative regulation of gene silencing by regulatory ncRNA	biological_process	Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
GO:0060970	embryonic heart tube dorsal/ventral pattern formation	biological_process	The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.
GO:0060971	embryonic heart tube left/right pattern formation	biological_process	The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.
GO:0060972	left/right pattern formation	biological_process	The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
GO:0060973	cell migration involved in heart development	biological_process	The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.
GO:0060974	cell migration involved in heart formation	biological_process	The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.
GO:0060975	cardioblast migration to the midline involved in heart field formation	biological_process	The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
GO:0060976	coronary vasculature development	biological_process	The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.
GO:0060977	coronary vasculature morphogenesis	biological_process	The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	biological_process	Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis	biological_process	The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.
GO:0060980	cell migration involved in coronary vasculogenesis	biological_process	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.
GO:0060981	cell migration involved in coronary angiogenesis	biological_process	The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.
GO:0060982	coronary artery morphogenesis	biological_process	The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.
GO:0060983	epicardium-derived cardiac vascular smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
GO:0060984	epicardium-derived cardiac vascular smooth muscle cell development	biological_process	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.
GO:0060985	epicardium-derived cardiac vascular smooth muscle cell fate commitment	biological_process	The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.
GO:0060986	endocrine hormone secretion	biological_process	The regulated release of a hormone into the circulatory system.
GO:0060987	lipid tube	cellular_component	A macromolecular complex that contains a tube of lipid surrounded by a protein coat.
GO:0060988	lipid tube assembly	biological_process	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.
GO:0060989	lipid tube assembly involved in organelle fusion	biological_process	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.
GO:0060990	lipid tube assembly involved in organelle fission	biological_process	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.
GO:0060992	response to fungicide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.
GO:0060993	kidney morphogenesis	biological_process	Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0060995	cell-cell signaling involved in kidney development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.
GO:0060996	dendritic spine development	biological_process	The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
GO:0060997	dendritic spine morphogenesis	biological_process	The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
GO:0060998	regulation of dendritic spine development	biological_process	Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
GO:0060999	positive regulation of dendritic spine development	biological_process	Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
GO:0061000	negative regulation of dendritic spine development	biological_process	Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
GO:0061001	regulation of dendritic spine morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
GO:0061002	negative regulation of dendritic spine morphogenesis	biological_process	Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
GO:0061003	positive regulation of dendritic spine morphogenesis	biological_process	Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
GO:0061004	pattern specification involved in kidney development	biological_process	Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.
GO:0061005	cell differentiation involved in kidney development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.
GO:0061006	regulation of cell proliferation involved in kidney morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.
GO:0061007	hepaticobiliary system process	biological_process	An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
GO:0061008	hepaticobiliary system development	biological_process	The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
GO:0061009	common bile duct development	biological_process	The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine.
GO:0061010	gallbladder development	biological_process	The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile.
GO:0061011	hepatic duct development	biological_process	The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.
GO:0061013	regulation of mRNA catabolic process	biological_process	Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0061014	positive regulation of mRNA catabolic process	biological_process	Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GO:0061015	snRNA import into nucleus	biological_process	The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.
GO:0061016	snRNA localization to Cajal body	biological_process	The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.
GO:0061017	hepatoblast differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.
GO:0061024	membrane organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0061025	membrane fusion	biological_process	The membrane organization process that joins two lipid bilayers to form a single membrane.
GO:0061026	cardiac muscle tissue regeneration	biological_process	The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
GO:0061027	umbilical cord development	biological_process	The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.
GO:0061028	establishment of endothelial barrier	biological_process	The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
GO:0061029	eyelid development in camera-type eye	biological_process	The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	biological_process	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.
GO:0061031	endodermal digestive tract morphogenesis	biological_process	The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.
GO:0061032	visceral serous pericardium development	biological_process	The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.
GO:0061033	secretion by lung epithelial cell involved in lung growth	biological_process	The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.
GO:0061034	olfactory bulb mitral cell layer development	biological_process	The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.
GO:0061035	regulation of cartilage development	biological_process	Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0061036	positive regulation of cartilage development	biological_process	Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0061037	negative regulation of cartilage development	biological_process	Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
GO:0061038	uterus morphogenesis	biological_process	The process in which anatomical structures of the uterus are generated and organized.
GO:0061040	female gonad morphogenesis	biological_process	The process in which a female gonad is generated and organized.
GO:0061041	regulation of wound healing	biological_process	Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GO:0061042	vascular wound healing	biological_process	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GO:0061043	regulation of vascular wound healing	biological_process	Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GO:0061044	negative regulation of vascular wound healing	biological_process	Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
GO:0061045	negative regulation of wound healing	biological_process	Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GO:0061046	regulation of branching involved in lung morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
GO:0061047	positive regulation of branching involved in lung morphogenesis	biological_process	Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
GO:0061048	negative regulation of branching involved in lung morphogenesis	biological_process	Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
GO:0061049	cell growth involved in cardiac muscle cell development	biological_process	The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	biological_process	Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	biological_process	Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	biological_process	Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
GO:0061053	somite development	biological_process	The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
GO:0061054	dermatome development	biological_process	The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
GO:0061055	myotome development	biological_process	The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.
GO:0061056	sclerotome development	biological_process	The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
GO:0061057	peptidoglycan recognition protein signaling pathway	biological_process	The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
GO:0061058	regulation of peptidoglycan recognition protein signaling pathway	biological_process	Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
GO:0061059	positive regulation of peptidoglycan recognition protein signaling pathway	biological_process	Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
GO:0061060	negative regulation of peptidoglycan recognition protein signaling pathway	biological_process	Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
GO:0061061	muscle structure development	biological_process	The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
GO:0061062	regulation of nematode larval development	biological_process	Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
GO:0061063	positive regulation of nematode larval development	biological_process	Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
GO:0061064	negative regulation of nematode larval development	biological_process	Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
GO:0061065	regulation of dauer larval development	biological_process	Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
GO:0061066	positive regulation of dauer larval development	biological_process	Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
GO:0061067	negative regulation of dauer larval development	biological_process	Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
GO:0061068	urethra development	biological_process	The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.
GO:0061069	male urethra development	biological_process	The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.
GO:0061070	female urethra development	biological_process	The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.
GO:0061071	urethra epithelium development	biological_process	The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.
GO:0061072	iris morphogenesis	biological_process	The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.
GO:0061073	ciliary body morphogenesis	biological_process	The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
GO:0061074	regulation of neural retina development	biological_process	Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
GO:0061075	positive regulation of neural retina development	biological_process	Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
GO:0061076	negative regulation of neural retina development	biological_process	Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
GO:0061077	chaperone-mediated protein folding	biological_process	The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
GO:0061078	positive regulation of prostaglandin secretion involved in immune response	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.
GO:0061079	left horn of sinus venosus development	biological_process	The progression of the left horn of the sinus venosus from its initial formation to the mature structure.
GO:0061080	right horn of sinus venosus development	biological_process	The progression of the right horn of the sinus venosus from its formation to the mature structure.
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	biological_process	Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.
GO:0061082	myeloid leukocyte cytokine production	biological_process	Any process that contributes to cytokine production by a myeloid cell.
GO:0061083	regulation of protein refolding	biological_process	Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
GO:0061084	negative regulation of protein refolding	biological_process	Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
GO:0061085	regulation of histone H3-K27 methylation	biological_process	Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
GO:0061086	negative regulation of histone H3-K27 methylation	biological_process	Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
GO:0061087	positive regulation of histone H3-K27 methylation	biological_process	Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
GO:0061091	regulation of phospholipid translocation	biological_process	Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
GO:0061092	positive regulation of phospholipid translocation	biological_process	Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
GO:0061093	negative regulation of phospholipid translocation	biological_process	Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
GO:0061094	regulation of turning behavior involved in mating	biological_process	Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
GO:0061095	positive regulation of turning behavior involved in mating	biological_process	Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
GO:0061096	negative regulation of turning behavior involved in mating	biological_process	Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
GO:0061097	regulation of protein tyrosine kinase activity	biological_process	Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.
GO:0061098	positive regulation of protein tyrosine kinase activity	biological_process	Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
GO:0061099	negative regulation of protein tyrosine kinase activity	biological_process	Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
GO:0061100	lung neuroendocrine cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.
GO:0061101	neuroendocrine cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.
GO:0061102	stomach neuroendocrine cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
GO:0061103	carotid body glomus cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.
GO:0061104	adrenal chromaffin cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
GO:0061105	regulation of stomach neuroendocrine cell differentiation	biological_process	Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	biological_process	Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
GO:0061107	seminal vesicle development	biological_process	The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.
GO:0061108	seminal vesicle epithelium development	biological_process	The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.
GO:0061109	dense core granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.
GO:0061110	dense core granule biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.
GO:0061111	epithelial-mesenchymal cell signaling involved in lung development	biological_process	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.
GO:0061112	negative regulation of bud outgrowth involved in lung branching	biological_process	Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.
GO:0061113	pancreas morphogenesis	biological_process	Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.
GO:0061114	branching involved in pancreas morphogenesis	biological_process	The process in which the branches of the pancreas are generated and organized.
GO:0061115	lung proximal/distal axis specification	biological_process	The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.
GO:0061116	ductus venosus closure	biological_process	The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.
GO:0061117	negative regulation of heart growth	biological_process	Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
GO:0061118	regulation of positive chemotaxis to cAMP	biological_process	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
GO:0061119	regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	biological_process	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
GO:0061120	regulation of positive chemotaxis to cAMP by DIF-1	biological_process	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
GO:0061121	regulation of positive chemotaxis to cAMP by DIF-2	biological_process	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
GO:0061122	positive regulation of positive chemotaxis to cAMP	biological_process	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
GO:0061123	negative regulation of positive chemotaxis to cAMP	biological_process	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
GO:0061124	positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	biological_process	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
GO:0061125	negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	biological_process	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
GO:0061126	positive regulation of positive chemotaxis to cAMP by DIF-1	biological_process	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
GO:0061127	negative regulation of positive chemotaxis to cAMP by DIF-1	biological_process	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
GO:0061128	positive regulation of chemotaxis to cAMP by DIF-2	biological_process	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
GO:0061129	negative regulation of positive chemotaxis to cAMP by DIF-2	biological_process	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
GO:0061130	pancreatic bud formation	biological_process	The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.
GO:0061131	pancreas field specification	biological_process	The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.
GO:0061132	pancreas induction	biological_process	The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.
GO:0061133	endopeptidase activator activity	molecular_function	Binds to and increases the activity of an endopeptidase.
GO:0061134	peptidase regulator activity	molecular_function	Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
GO:0061135	endopeptidase regulator activity	molecular_function	Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
GO:0061136	regulation of proteasomal protein catabolic process	biological_process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
GO:0061137	bud dilation	biological_process	The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.
GO:0061138	morphogenesis of a branching epithelium	biological_process	The process in which the anatomical structures of a branched epithelium are generated and organized.
GO:0061139	bud field specification	biological_process	The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0061140	lung secretory cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.
GO:0061141	lung ciliated cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.
GO:0061142	mesothelial-mesenchymal cell signaling involved in early lung development	biological_process	Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.
GO:0061143	alveolar primary septum development	biological_process	The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.
GO:0061144	alveolar secondary septum development	biological_process	The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.
GO:0061145	lung smooth muscle development	biological_process	The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.
GO:0061146	Peyer's patch morphogenesis	biological_process	The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.
GO:0061147	endocardial endothelium development	biological_process	The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0061148	extracellular matrix organization involved in endocardium development	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
GO:0061150	renal system segmentation	biological_process	The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.
GO:0061152	trachea submucosa development	biological_process	The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.
GO:0061153	trachea gland development	biological_process	The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.
GO:0061154	endothelial tube morphogenesis	biological_process	The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
GO:0061155	pulmonary artery endothelial tube morphogenesis	biological_process	The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.
GO:0061156	pulmonary artery morphogenesis	biological_process	The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.
GO:0061157	mRNA destabilization	biological_process	Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.
GO:0061158	3'-UTR-mediated mRNA destabilization	biological_process	An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
GO:0061159	establishment of bipolar cell polarity involved in cell morphogenesis	biological_process	The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.
GO:0061160	regulation of establishment of bipolar cell polarity regulating cell shape	biological_process	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.
GO:0061161	positive regulation of establishment of bipolar cell polarity regulating cell shape	biological_process	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.
GO:0061162	establishment of monopolar cell polarity	biological_process	The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.
GO:0061163	endoplasmic reticulum polarization	biological_process	The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.
GO:0061168	regulation of hair follicle placode formation	biological_process	Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
GO:0061169	positive regulation of hair placode formation	biological_process	Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
GO:0061170	negative regulation of hair follicle placode formation	biological_process	Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
GO:0061171	establishment of bipolar cell polarity	biological_process	The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.
GO:0061172	regulation of establishment of bipolar cell polarity	biological_process	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.
GO:0061173	positive regulation of establishment of bipolar cell polarity	biological_process	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.
GO:0061174	type I terminal bouton	cellular_component	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
GO:0061175	type II terminal bouton	cellular_component	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
GO:0061176	type Ib terminal bouton	cellular_component	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.
GO:0061177	type Is terminal bouton	cellular_component	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	biological_process	Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
GO:0061180	mammary gland epithelium development	biological_process	The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
GO:0061181	regulation of chondrocyte development	biological_process	Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
GO:0061182	negative regulation of chondrocyte development	biological_process	Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
GO:0061183	regulation of dermatome development	biological_process	Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
GO:0061184	positive regulation of dermatome development	biological_process	Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
GO:0061185	negative regulation of dermatome development	biological_process	Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
GO:0061186	negative regulation of silent mating-type cassette heterochromatin formation	biological_process	Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.
GO:0061187	regulation of rDNA heterochromatin formation	biological_process	Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation.
GO:0061188	negative regulation of rDNA heterochromatin formation	biological_process	Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation.
GO:0061189	positive regulation of sclerotome development	biological_process	Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
GO:0061190	regulation of sclerotome development	biological_process	Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
GO:0061191	positive regulation of vacuole fusion, non-autophagic	biological_process	Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
GO:0061192	negative regulation of vacuole fusion, non-autophagic	biological_process	Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
GO:0061193	taste bud development	biological_process	The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.
GO:0061194	taste bud morphogenesis	biological_process	The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.
GO:0061195	taste bud formation	biological_process	The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.
GO:0061196	fungiform papilla development	biological_process	The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.
GO:0061197	fungiform papilla morphogenesis	biological_process	The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.
GO:0061198	fungiform papilla formation	biological_process	The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.
GO:0061199	striated muscle contraction involved in embryonic body morphogenesis	biological_process	The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.
GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle	cellular_component	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.
GO:0061201	clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen	cellular_component	The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.
GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.
GO:0061203	striated muscle paramyosin thick filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.
GO:0061204	paramyosin filament assembly or disassembly	biological_process	The formation or disassembly of a filament composed of paramyosin molecules.
GO:0061205	paramesonephric duct development	biological_process	The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.
GO:0061206	mesonephros morphogenesis	biological_process	The process in which the anatomical structures of the mesonephros are generated and organized.
GO:0061207	mesonephric juxtaglomerulus cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.
GO:0061208	cell differentiation involved in mesonephros development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.
GO:0061209	cell proliferation involved in mesonephros development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.
GO:0061210	cell-cell signaling involved in mesonephros development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.
GO:0061211	mesonephric collecting duct development	biological_process	The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
GO:0061212	mesonephric juxtaglomerular apparatus development	biological_process	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.
GO:0061213	positive regulation of mesonephros development	biological_process	Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0061214	mesonephric smooth muscle tissue development	biological_process	The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.
GO:0061215	mesonephric nephron development	biological_process	The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
GO:0061217	regulation of mesonephros development	biological_process	Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0061218	negative regulation of mesonephros development	biological_process	Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0061219	mesonephric mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.
GO:0061220	mesonephric macula densa development	biological_process	The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.
GO:0061221	mesonephric mesenchyme morphogenesis	biological_process	The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.
GO:0061222	mesonephric mesenchymal cell proliferation involved in mesonephros development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.
GO:0061223	mesonephric mesenchymal cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.
GO:0061224	mesonephric glomerulus development	biological_process	The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.
GO:0061225	mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development	biological_process	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
GO:0061226	proximal/distal pattern formation involved in mesonephric nephron development	biological_process	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).
GO:0061227	pattern specification involved in mesonephros development	biological_process	Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.
GO:0061228	mesonephric nephron morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.
GO:0061229	mesonephric juxtaglomerulus cell development	biological_process	The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.
GO:0061230	mesonephric juxtaglomerulus cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.
GO:0061231	mesonephric glomerulus vasculature development	biological_process	The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.
GO:0061232	mesonephric glomerular epithelium development	biological_process	The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
GO:0061233	mesonephric glomerular basement membrane development	biological_process	The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.
GO:0061234	mesonephric glomerulus morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.
GO:0061235	mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis	biological_process	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0061236	mesonephric comma-shaped body morphogenesis	biological_process	The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.
GO:0061237	convergent extension involved in mesonephric nephron morphogenesis	biological_process	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.
GO:0061238	establishment of planar polarity involved in mesonephric nephron morphogenesis	biological_process	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.
GO:0061239	mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0061240	mesonephric nephron tubule morphogenesis	biological_process	The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.
GO:0061241	mesonephric nephron epithelium development	biological_process	The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.
GO:0061242	mesonephric nephron tubule development	biological_process	The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.
GO:0061243	mesonephric renal vesicle morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
GO:0061244	mesonephric S-shaped body morphogenesis	biological_process	The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.
GO:0061245	establishment or maintenance of bipolar cell polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.
GO:0061246	establishment or maintenance of bipolar cell polarity regulating cell shape	biological_process	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.
GO:0061247	mesonephric glomerular mesangium development	biological_process	The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.
GO:0061248	mesonephric glomerulus vasculature morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.
GO:0061249	mesonephric glomerular capillary formation	biological_process	The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
GO:0061250	mesonephric glomerular epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
GO:0061251	mesonephric glomerular epithelial cell development	biological_process	The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
GO:0061252	mesonephric glomerular epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
GO:0061253	mesonephric glomerular parietal epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0061254	mesonephric glomerular parietal epithelial cell development	biological_process	The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0061255	mesonephric glomerular parietal epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
GO:0061256	mesonephric podocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
GO:0061257	mesonephric podocyte development	biological_process	The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
GO:0061258	mesonephric podocyte cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
GO:0061259	mesonephric glomerular mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.
GO:0061260	mesonephric mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.
GO:0061261	mesenchymal to epithelial transition involved in mesonephros morphogenesis	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.
GO:0061262	mesonephric renal vesicle formation	biological_process	The developmental process pertaining to the initial formation of the mesonephros.
GO:0061263	mesonephric glomerular mesangial cell development	biological_process	The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.
GO:0061264	mesonephric glomerular mesangial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.
GO:0061265	mesonephric nephron tubule epithelial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.
GO:0061266	mesonephric interstitial fibroblast differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.
GO:0061267	mesonephric interstitial fibroblast development	biological_process	The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.
GO:0061268	mesonephric interstitial fibroblast fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.
GO:0061269	mesonephric glomerular mesangial cell proliferation involved in mesonephros development	biological_process	The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.
GO:0061270	mesonephric intraglomerular mesangial cell proliferation	biological_process	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
GO:0061271	mesenchymal to epithelial transition involved in mesonephric renal vesicle formation	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.
GO:0061272	mesonephric connecting tubule development	biological_process	The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.
GO:0061273	mesonephric distal tubule morphogenesis	biological_process	The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.
GO:0061274	mesonephric distal tubule development	biological_process	The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.
GO:0061275	mesonephric proximal tubule development	biological_process	The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.
GO:0061276	mesonephric proximal tubule morphogenesis	biological_process	The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.
GO:0061277	mesonephric nephron tubule formation	biological_process	The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.
GO:0061278	epithelial cell migration involved in mesonephric nephron tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.
GO:0061279	epithelial cell migration involved in mesonephric distal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.
GO:0061280	epithelial cell migration involved in mesonephric proximal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.
GO:0061281	specification of mesonephric connecting tubule identity	biological_process	The process in which the connecting tubule of the mesonephric nephron acquires its identity.
GO:0061282	specification of mesonephric nephron tubule identity	biological_process	The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.
GO:0061283	specification of mesonephric distal tubule identity	biological_process	The process in which the distal tubule of the mesonephric nephron acquires its identity.
GO:0061284	specification of mesonephric proximal tubule identity	biological_process	The process in which the proximal tubule of the mesonephric nephron acquires its identity.
GO:0061285	mesonephric capsule development	biological_process	The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.
GO:0061286	mesonephric capsule morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
GO:0061287	mesonephric capsule formation	biological_process	The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
GO:0061288	mesonephric capsule specification	biological_process	The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0061289	Wnt signaling pathway involved in kidney development	biological_process	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.
GO:0061290	canonical Wnt signaling pathway involved in metanephric kidney development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061291	canonical Wnt signaling pathway involved in ureteric bud branching	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061292	canonical Wnt signaling pathway involved in mesonephros development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061293	canonical Wnt signaling pathway involved in mesonephric nephron development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061294	mesonephric renal vesicle induction	biological_process	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.
GO:0061295	regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	biological_process	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
GO:0061296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	biological_process	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
GO:0061297	positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	biological_process	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
GO:0061298	retina vasculature development in camera-type eye	biological_process	The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.
GO:0061299	retina vasculature morphogenesis in camera-type eye	biological_process	The process in which the vasculature of the retina is generated and organized.
GO:0061300	cerebellum vasculature development	biological_process	The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.
GO:0061301	cerebellum vasculature morphogenesis	biological_process	The process in which the vasculature of the cerebellum is generated and organized.
GO:0061302	smooth muscle cell-matrix adhesion	biological_process	The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.
GO:0061303	cornea development in camera-type eye	biological_process	The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.
GO:0061304	retinal blood vessel morphogenesis	biological_process	The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.
GO:0061305	maintenance of bipolar cell polarity regulating cell shape	biological_process	The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.
GO:0061307	cardiac neural crest cell differentiation involved in heart development	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.
GO:0061308	cardiac neural crest cell development involved in heart development	biological_process	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	biological_process	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.
GO:0061310	canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.
GO:0061311	cell surface receptor signaling pathway involved in heart development	biological_process	The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.
GO:0061313	fibroblast growth factor receptor signaling pathway involved in heart development	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.
GO:0061314	Notch signaling involved in heart development	biological_process	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.
GO:0061315	canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation	biological_process	The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells.
GO:0061316	canonical Wnt signaling pathway involved in heart development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
GO:0061318	renal filtration cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0061319	nephrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0061320	pericardial nephrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0061321	garland nephrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0061322	disseminated nephrocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0061323	cell proliferation involved in heart morphogenesis	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.
GO:0061324	canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	biological_process	The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.
GO:0061325	cell proliferation involved in outflow tract morphogenesis	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.
GO:0061326	renal tubule development	biological_process	The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
GO:0061327	anterior Malpighian tubule development	biological_process	The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.
GO:0061328	posterior Malpighian tubule development	biological_process	The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.
GO:0061329	Malpighian tubule principal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.
GO:0061330	Malpighian tubule stellate cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.
GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis	biological_process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.
GO:0061332	Malpighian tubule bud morphogenesis	biological_process	The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.
GO:0061333	renal tubule morphogenesis	biological_process	The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
GO:0061334	cell rearrangement involved in Malpighian tubule morphogenesis	biological_process	The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.
GO:0061335	cell growth involved in Malpighian tubule morphogenesis	biological_process	The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.
GO:0061336	cell morphogenesis involved in Malpighian tubule morphogenesis	biological_process	The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.
GO:0061337	cardiac conduction	biological_process	Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
GO:0061339	establishment or maintenance of monopolar cell polarity	biological_process	Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.
GO:0061340	establishment or maintenance of monopolar cell polarity regulating cell shape	biological_process	Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.
GO:0061341	non-canonical Wnt signaling pathway involved in heart development	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.
GO:0061342	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway	biological_process	Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.
GO:0061343	cell adhesion involved in heart morphogenesis	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
GO:0061344	regulation of cell adhesion involved in heart morphogenesis	biological_process	Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.
GO:0061345	planar cell polarity pathway involved in cardiac muscle cell fate commitment	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.
GO:0061346	planar cell polarity pathway involved in heart morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.
GO:0061351	neural precursor cell proliferation	biological_process	The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.
GO:0061352	cell chemotaxis involved in Malpighian tubule morphogenesis	biological_process	The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.
GO:0061355	Wnt protein secretion	biological_process	The controlled release of a Wnt protein from a cell.
GO:0061356	regulation of Wnt protein secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
GO:0061357	positive regulation of Wnt protein secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
GO:0061358	negative regulation of Wnt protein secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
GO:0061359	regulation of Wnt signaling pathway by Wnt protein secretion	biological_process	Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell.
GO:0061360	optic chiasma development	biological_process	The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.
GO:0061361	positive regulation of maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.
GO:0061362	negative regulation of maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.
GO:0061363	negative regulation of progesterone biosynthesis involved in luteolysis	biological_process	Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.
GO:0061364	apoptotic process involved in luteolysis	biological_process	The apoptotic process that contributes to luteolysis.
GO:0061365	positive regulation of triglyceride lipase activity	biological_process	Any process that increases the activity of triglyceride lipase.
GO:0061366	behavioral response to chemical pain	biological_process	Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.
GO:0061367	behavioral response to acetic acid induced pain	biological_process	Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.
GO:0061368	behavioral response to formalin induced pain	biological_process	Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.
GO:0061369	negative regulation of testicular blood vessel morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.
GO:0061370	testosterone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.
GO:0061371	determination of heart left/right asymmetry	biological_process	Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
GO:0061373	mammillary axonal complex development	biological_process	The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.
GO:0061374	mammillothalamic axonal tract development	biological_process	The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.
GO:0061375	mammillotectal axonal tract development	biological_process	The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.
GO:0061376	mammillotegmental axonal tract development	biological_process	The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.
GO:0061377	mammary gland lobule development	biological_process	The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.
GO:0061378	corpora quadrigemina development	biological_process	The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.
GO:0061379	inferior colliculus development	biological_process	The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.
GO:0061380	superior colliculus development	biological_process	The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.
GO:0061381	cell migration in diencephalon	biological_process	The orderly movement of a cell that will reside in the diencephalon.
GO:0061382	Malpighian tubule tip cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.
GO:0061383	trabecula morphogenesis	biological_process	The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
GO:0061384	heart trabecula morphogenesis	biological_process	The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
GO:0061385	fibroblast proliferation involved in heart morphogenesis	biological_process	The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.
GO:0061386	closure of optic fissure	biological_process	The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
GO:0061387	regulation of extent of cell growth	biological_process	Any process that modulates the extent of cell growth.
GO:0061388	regulation of rate of cell growth	biological_process	Any process that modulates the rate of cell growth.
GO:0061389	regulation of direction of cell growth	biological_process	Any process that modulates the direction of cell growth.
GO:0061390	positive regulation of direction of cell growth	biological_process	Any process that increases the direction of cell growth.
GO:0061391	negative regulation of direction of cell growth	biological_process	Any process that decreases the direction of cell growth.
GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.
GO:0061406	positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.
GO:0061407	positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.
GO:0061408	positive regulation of transcription from RNA polymerase II promoter in response to heat stress	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0061411	positive regulation of transcription from RNA polymerase II promoter in response to cold	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
GO:0061413	regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	biological_process	A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
GO:0061414	positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	biological_process	A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
GO:0061415	negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	biological_process	A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
GO:0061417	negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress	biological_process	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	biological_process	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	biological_process	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
GO:0061425	positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter	biological_process	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process.
GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia	biological_process	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
GO:0061429	positive regulation of transcription from RNA polymerase II promoter by oleic acid	biological_process	Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:0061430	bone trabecula morphogenesis	biological_process	The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
GO:0061431	cellular response to methionine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.
GO:0061433	cellular response to caloric restriction	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.
GO:0061435	positive regulation of transcription from a mobile element promoter	biological_process	Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.
GO:0061436	establishment of skin barrier	biological_process	Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
GO:0061437	renal system vasculature development	biological_process	The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.
GO:0061438	renal system vasculature morphogenesis	biological_process	The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.
GO:0061439	kidney vasculature morphogenesis	biological_process	The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.
GO:0061440	kidney vasculature development	biological_process	The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.
GO:0061441	renal artery morphogenesis	biological_process	The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.
GO:0061442	cardiac muscle cell fate determination	biological_process	The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
GO:0061443	endocardial cushion cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.
GO:0061444	endocardial cushion cell development	biological_process	The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.
GO:0061445	endocardial cushion cell fate commitment	biological_process	The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.
GO:0061446	endocardial cushion cell fate determination	biological_process	The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
GO:0061447	endocardial cushion cell fate specification	biological_process	The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
GO:0061448	connective tissue development	biological_process	The progression of a connective tissue over time, from its formation to the mature structure.
GO:0061449	olfactory bulb tufted cell development	biological_process	The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0061450	trophoblast cell migration	biological_process	Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.
GO:0061451	retrotrapezoid nucleus development	biological_process	The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.
GO:0061452	retrotrapezoid nucleus neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.
GO:0061453	interstitial cell of Cajal differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.
GO:0061454	release of sequestered calcium ion into cytosol by Golgi	biological_process	The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.
GO:0061456	mesenchymal stem cell migration involved in uteric bud morphogenesis	biological_process	The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0061457	mesonephric cell migration involved in male gonad development	biological_process	The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.
GO:0061458	reproductive system development	biological_process	The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.
GO:0061459	L-arginine transmembrane transporter activity	molecular_function	Enables the transfer of L-arginine from one side of a membrane to the other.
GO:0061462	protein localization to lysosome	biological_process	A process in which a protein is transported to, or maintained in, a location within a lysosome.
GO:0061463	O-acetyl-ADP-ribose deacetylase activity	molecular_function	Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.
GO:0061468	karyomere	cellular_component	A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.
GO:0061469	regulation of type B pancreatic cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.
GO:0061470	T follicular helper cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.
GO:0061471	karyomere assembly	biological_process	The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.
GO:0061472	karyomere membrane fusion	biological_process	Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.
GO:0061473	murein tripeptide carboxypeptidase activity	molecular_function	Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.
GO:0061474	phagolysosome membrane	cellular_component	The lipid bilayer surrounding a phagolysosome.
GO:0061475	cytosolic valyl-tRNA aminoacylation	biological_process	The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0061476	response to anticoagulant	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.
GO:0061477	response to aromatase inhibitor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.
GO:0061478	response to platelet aggregation inhibitor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.
GO:0061479	response to reverse transcriptase inhibitor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.
GO:0061480	response to asparaginase	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.
GO:0061481	response to TNF agonist	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.
GO:0061482	response to irinotecan	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.
GO:0061483	sulfinylpropanyl adenylate synthase	molecular_function	Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H+ + phosphate.
GO:0061484	hematopoietic stem cell homeostasis	biological_process	Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.
GO:0061485	memory T cell proliferation	biological_process	The expansion of a memory T cell population by cell division.
GO:0061486	high-affinity fructose transmembrane transporter activity	molecular_function	Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0061492	asymmetric protein localization to old or new spindle pole body	biological_process	Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.
GO:0061493	central plaque of mitotic spindle pole body	cellular_component	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.
GO:0061496	half bridge of mitotic spindle pole body	cellular_component	Structure adjacent to the plaques of the mitotic spindle pole body.
GO:0061497	inner plaque of mitotic spindle pole body	cellular_component	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.
GO:0061498	intermediate layer of mitotic spindle pole body	cellular_component	Structure between the central and outer plaques of the mitotic spindle pole body.
GO:0061499	outer plaque of mitotic spindle pole body	cellular_component	One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.
GO:0061501	2',3'-cyclic GMP-AMP synthase activity	molecular_function	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).
GO:0061502	early endosome to recycling endosome transport	biological_process	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.
GO:0061503	tRNA threonylcarbamoyladenosine dehydratase	molecular_function	Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.
GO:0061504	cyclic threonylcarbamoyladenosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
GO:0061507	2',3'-cyclic GMP-AMP binding	molecular_function	Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.
GO:0061509	asymmetric protein localization to old mitotic spindle pole body	biological_process	Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.
GO:0061510	asymmetric protein localization to new mitotic spindle pole body	biological_process	Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.
GO:0061511	centriole elongation	biological_process	The centrosome organization process by which a centriole increases in length as part of the process of replication.
GO:0061512	protein localization to cilium	biological_process	A process in which a protein is transported to, or maintained in, a location within a cilium.
GO:0061513	glucose 6-phosphate:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).
GO:0061514	interleukin-34-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-34 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0061515	myeloid cell development	biological_process	The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.
GO:0061516	monocyte proliferation	biological_process	The expansion of a monocyte population by cell division.
GO:0061517	macrophage proliferation	biological_process	The expansion of a macrophage population by cell division.
GO:0061518	microglial cell proliferation	biological_process	The expansion of a microglial cell population by cell division.
GO:0061519	macrophage homeostasis	biological_process	The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0061520	Langerhans cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a Langerhans cell.
GO:0061521	hepatic stellate cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.
GO:0061522	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity	molecular_function	Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA.
GO:0061523	cilium disassembly	biological_process	A cellular process that results in the breakdown of a cilium.
GO:0061524	central canal development	biological_process	The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.
GO:0061525	hindgut development	biological_process	The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.
GO:0061526	acetylcholine secretion	biological_process	The regulated release of acetylcholine by a cell.
GO:0061527	dopamine secretion, neurotransmission	biological_process	The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.
GO:0061528	aspartate secretion	biological_process	The regulated release of aspartate by a cell.
GO:0061529	epinephrine secretion, neurotransmission	biological_process	The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.
GO:0061530	aspartate secretion, neurotransmission	biological_process	The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter.
GO:0061531	primary amine secretion	biological_process	The regulated release of a primary amine by a cell.
GO:0061532	primary amine secretion, neurotransmission	biological_process	The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.
GO:0061533	norepinephrine secretion, neurotransmission	biological_process	The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.
GO:0061534	gamma-aminobutyric acid secretion, neurotransmission	biological_process	The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.
GO:0061535	glutamate secretion, neurotransmission	biological_process	The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.
GO:0061536	glycine secretion	biological_process	The controlled release of glycine by a cell.
GO:0061537	glycine secretion, neurotransmission	biological_process	The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter.
GO:0061538	histamine secretion, neurotransmission	biological_process	The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.
GO:0061539	octopamine secretion	biological_process	The controlled release of octopamine by a cell.
GO:0061540	octopamine secretion, neurotransmission	biological_process	The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter.
GO:0061541	rhabdomere morphogenesis	biological_process	The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
GO:0061542	3-demethylubiquinol-n 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.
GO:0061543	3-demethylubiquinol-6 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6.
GO:0061544	peptide secretion, neurotransmission	biological_process	The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter.
GO:0061545	tyramine secretion	biological_process	The regulated release of a tyramine by a cell.
GO:0061546	tyramine secretion, neurotransmission	biological_process	The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter.
GO:0061547	glycogen synthase activity, transferring glucose-1-phosphate	molecular_function	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.
GO:0061548	ganglion development	biological_process	The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.
GO:0061549	sympathetic ganglion development	biological_process	The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.
GO:0061550	cranial ganglion development	biological_process	The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.
GO:0061551	trigeminal ganglion development	biological_process	The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.
GO:0061552	ganglion morphogenesis	biological_process	The process in which the anatomical structures of ganglion are generated and organized.
GO:0061553	ganglion maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.
GO:0061554	ganglion formation	biological_process	The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.
GO:0061555	ganglion structural organization	biological_process	The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.
GO:0061556	trigeminal ganglion morphogenesis	biological_process	The process in which the anatomical structure of a trigeminal ganglion is generated and organized.
GO:0061557	trigeminal ganglion maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.
GO:0061558	cranial ganglion maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.
GO:0061559	cranial ganglion morphogenesis	biological_process	The process in which the anatomical structure of a cranial ganglion is generated and organized.
GO:0061560	cranial ganglion formation	biological_process	The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.
GO:0061561	trigeminal ganglion formation	biological_process	The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.
GO:0061562	cranial ganglion structural organization	biological_process	The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.
GO:0061563	trigeminal ganglion structural organization	biological_process	The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.
GO:0061564	axon development	biological_process	The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).
GO:0061565	dAMP phosphorylation	biological_process	The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.
GO:0061566	CMP phosphorylation	biological_process	The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.
GO:0061567	dCMP phosphorylation	biological_process	The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.
GO:0061572	actin filament bundle organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.
GO:0061573	actin filament bundle retrograde transport	biological_process	A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.
GO:0061574	ASAP complex	cellular_component	A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	molecular_function	Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.
GO:0061576	acyl-CoA ceramide synthase complex	cellular_component	A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.
GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	biological_process	A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.
GO:0061578	K63-linked deubiquitinase activity	molecular_function	Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys63 residue of ubiquitin.
GO:0061579	N-acyl homoserine lactone synthase activity	molecular_function	Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.
GO:0061580	colon epithelial cell migration	biological_process	The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.
GO:0061581	corneal epithelial cell migration	biological_process	The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.
GO:0061582	intestinal epithelial cell migration	biological_process	The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.
GO:0061583	colon epithelial cell chemotaxis	biological_process	The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0061584	orexin secretion	biological_process	The controlled release of orexin from a cell or a tissue.
GO:0061585	orexin secretion, neurotransmission	biological_process	The controlled release of orexin from a cell in which orexin acts as a neurotransmitter.
GO:0061586	positive regulation of transcription by transcription factor localization	biological_process	Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.
GO:0061588	calcium activated phospholipid scrambling	biological_process	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
GO:0061589	calcium activated phosphatidylserine scrambling	biological_process	The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
GO:0061590	calcium activated phosphatidylcholine scrambling	biological_process	The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
GO:0061591	calcium activated galactosylceramide scrambling	biological_process	The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
GO:0061592	phosphatidylserine exposure on osteoblast involved in bone mineralization	biological_process	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization.
GO:0061593	sulfoquinovose isomerase activity	molecular_function	Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose.
GO:0061594	6-deoxy-6-sulfofructose kinase activity	molecular_function	Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.
GO:0061595	6-deoxy-6-sulfofructose-1-phosphate aldolase activity	molecular_function	Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.
GO:0061596	3-sulfolactaldehyde reductase activity	molecular_function	Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.
GO:0061598	molybdopterin adenylyltransferase activity	molecular_function	Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
GO:0061599	molybdopterin molybdotransferase activity	molecular_function	Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
GO:0061602	molybdenum cofactor cytidylyltransferase activity	molecular_function	Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.
GO:0061603	molybdenum cofactor guanylyltransferase activity	molecular_function	Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.
GO:0061604	molybdopterin-synthase sulfurtransferase activity	molecular_function	Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.
GO:0061605	molybdopterin-synthase adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.
GO:0061606	N-terminal protein amino acid propionylation	biological_process	The propionylation of the N-terminal amino acid of proteins.
GO:0061607	peptide alpha-N-propionyltransferase activity	molecular_function	Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.
GO:0061608	nuclear import signal receptor activity	molecular_function	Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
GO:0061609	fructose-1-phosphate aldolase activity	molecular_function	Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
GO:0061610	glycerol to glycerone phosphate metabolic process	biological_process	The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.
GO:0061611	mannose to fructose-6-phosphate metabolic process	biological_process	The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.
GO:0061612	galactose to glucose-1-phosphate metabolic process	biological_process	The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.
GO:0061613	glycolytic process from glycerol	biological_process	The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.
GO:0061614	miRNA transcription	biological_process	The cellular synthesis of microRNA (miRNA) transcripts. MicroRNA genes are synthesized as primary (pri) miRNA transcripts and subsequently processed to produce the ~22nt miRNAs that function in gene regulation.
GO:0061615	glycolytic process through fructose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
GO:0061616	glycolytic process from fructose through fructose-6-phosphate	biological_process	The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.
GO:0061617	MICOS complex	cellular_component	Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.
GO:0061619	glycolytic process from mannose through fructose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
GO:0061620	glycolytic process through glucose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.
GO:0061621	canonical glycolysis	biological_process	The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
GO:0061622	glycolytic process through glucose-1-phosphate	biological_process	The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
GO:0061623	glycolytic process from galactose	biological_process	The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.
GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
GO:0061625	glycolytic process through fructose-1-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.
GO:0061626	pharyngeal arch artery morphogenesis	biological_process	The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.
GO:0061627	S-methylmethionine-homocysteine S-methyltransferase activity	molecular_function	Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.
GO:0061628	H3K27me3 modified histone binding	molecular_function	Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	molecular_function	Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
GO:0061630	ubiquitin protein ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
GO:0061631	ubiquitin conjugating enzyme activity	molecular_function	Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y = Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
GO:0061632	RNA lariat debranching enzyme activator activity	molecular_function	Binds to and increases the activity of an RNA lariat debranching enzyme.
GO:0061633	transport-coupled glycolytic process through glucose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.
GO:0061634	alpha-D-xyloside xylohydrolase	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.
GO:0061635	regulation of protein complex stability	biological_process	Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.
GO:0061638	CENP-A containing chromatin	cellular_component	The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.
GO:0061639	Cdv-dependent cytokinesis	biological_process	A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.
GO:0061640	cytoskeleton-dependent cytokinesis	biological_process	A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.
GO:0061642	chemoattraction of axon	biological_process	The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
GO:0061643	chemorepulsion of axon	biological_process	The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
GO:0061644	protein localization to CENP-A containing chromatin	biological_process	Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.
GO:0061645	endocytic patch	cellular_component	The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle.
GO:0061646	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.
GO:0061647	histone H3-K9 modification	biological_process	The modification of histone H3 at a lysine in position 9 of the histone.
GO:0061648	tooth replacement	biological_process	The process whose specific outcome is the replacement of an existing tooth with another tooth.
GO:0061649	ubiquitin modification-dependent histone binding	molecular_function	Binding to a histone protein in which a residue has been modified by ubiquitination.
GO:0061650	ubiquitin-like protein conjugating enzyme activity	molecular_function	Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.
GO:0061651	Atg12 conjugating enzyme activity	molecular_function	Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.
GO:0061652	FAT10 conjugating enzyme activity	molecular_function	Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.
GO:0061653	ISG15 conjugating enzyme activity	molecular_function	Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.
GO:0061654	NEDD8 conjugating enzyme activity	molecular_function	Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.
GO:0061655	Pup conjugating enzyme activity	molecular_function	Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.
GO:0061656	SUMO conjugating enzyme activity	molecular_function	Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.
GO:0061657	UFM1 conjugating enzyme activity	molecular_function	Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.
GO:0061658	URM1 conjugating enzyme activity	molecular_function	Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y = Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.
GO:0061659	ubiquitin-like protein ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
GO:0061660	Atg12 ligase activity	molecular_function	Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.
GO:0061661	FAT10 ligase activity	molecular_function	Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S = X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.
GO:0061662	ISG15 ligase activity	molecular_function	Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S = X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.
GO:0061663	NEDD8 ligase activity	molecular_function	Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S = X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.
GO:0061664	Pup ligase activity	molecular_function	Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S = X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.
GO:0061665	SUMO ligase activity	molecular_function	Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
GO:0061666	UFM1 ligase activity	molecular_function	Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S = X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.
GO:0061667	URM1 ligase activity	molecular_function	Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S = X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.
GO:0061668	mitochondrial ribosome assembly	biological_process	The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.
GO:0061669	spontaneous neurotransmitter secretion	biological_process	Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.
GO:0061670	evoked neurotransmitter secretion	biological_process	Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.
GO:0061671	Cbp3p-Cbp6 complex	cellular_component	A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.
GO:0061672	glutathione hydrolase complex	cellular_component	Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.
GO:0061673	mitotic spindle astral microtubule	cellular_component	Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
GO:0061674	gap filling involved in double-strand break repair via nonhomologous end joining	biological_process	Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.
GO:0061675	RBL family protein binding	molecular_function	Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.
GO:0061676	importin-alpha family protein binding	molecular_function	Binding to a member of the importin-alpha family.
GO:0061677	2-dehydro-3-deoxy-D-gluconate aldolase activity	molecular_function	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate = pyruvate + D-glyceraldehyde.
GO:0061678	Entner-Doudoroff pathway	biological_process	A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.
GO:0061679	Entner-Doudoroff pathway through gluconate	biological_process	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.
GO:0061680	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde	biological_process	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.
GO:0061681	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate	biological_process	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.
GO:0061682	seminal vesicle morphogenesis	biological_process	The process in which the anatomical structures of a seminal vesicle are generated and organized.
GO:0061683	branching involved in seminal vesicle morphogenesis	biological_process	The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.
GO:0061684	chaperone-mediated autophagy	biological_process	The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
GO:0061685	diphthine methylesterase activity	molecular_function	Catalysis of the reaction: diphthine methyl ester + H2O = diphthine + H+ + methanol.
GO:0061686	hercynylcysteine sulfoxide synthase activity	molecular_function	Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 = hercynylcysteine sulfoxide + H2O.
GO:0061687	detoxification of inorganic compound	biological_process	Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.
GO:0061688	glycolytic process via Entner-Doudoroff Pathway	biological_process	A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.
GO:0061689	tricellular tight junction	cellular_component	An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.
GO:0061690	lipoamidase activity	molecular_function	Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.
GO:0061691	detoxification of hydrogen peroxide	biological_process	Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
GO:0061692	cellular detoxification of hydrogen peroxide	biological_process	Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
GO:0061693	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity	molecular_function	Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.
GO:0061694	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex	cellular_component	A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.
GO:0061695	transferase complex, transferring phosphorus-containing groups	cellular_component	A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0061696	pituitary gonadotropin complex	cellular_component	A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.
GO:0061697	protein-glutaryllysine deglutarylase activity	molecular_function	Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0061698	protein deglutarylation	biological_process	The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.
GO:0061699	peptidyl-lysine deglutarylation	biological_process	The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.
GO:0061700	GATOR2 complex	cellular_component	A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.
GO:0061701	bacterial outer membrane vesicle	cellular_component	A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.
GO:0061702	canonical inflammasome complex	cellular_component	A cytosolic protein complex that is capable of activating caspase-1.
GO:0061703	pyroptosome complex	cellular_component	A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.
GO:0061704	glycolytic process from sucrose	biological_process	The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
GO:0061705	sucrose catabolic process to fructose-6-phosphate through glucose and fructose	biological_process	The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.
GO:0061706	glycolytic process from sucrose through glucose and fructose	biological_process	The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
GO:0061707	extracellular exosome macropinocytosis	biological_process	The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.
GO:0061708	tRNA-5-taurinomethyluridine 2-sulfurtransferase	molecular_function	Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.
GO:0061709	reticulophagy	biological_process	The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.
GO:0061710	L-threonylcarbamoyladenylate synthase	molecular_function	Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H2O.
GO:0061711	N(6)-L-threonylcarbamoyladenine synthase activity	molecular_function	Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.
GO:0061712	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase	molecular_function	Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.
GO:0061713	anterior neural tube closure	biological_process	The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.
GO:0061714	folic acid receptor activity	molecular_function	Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.
GO:0061716	miRNA export from nucleus	biological_process	The directed movement of a processed miRNA from the nucleus to the cytoplasm.
GO:0061718	glucose catabolic process to pyruvate	biological_process	The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.
GO:0061719	glucose catabolic process to pyruvate utilizing ADP	biological_process	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.
GO:0061720	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
GO:0061721	6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).
GO:0061722	sulphoglycolysis	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.
GO:0061723	glycophagy	biological_process	The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.
GO:0061724	lipophagy	biological_process	The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.
GO:0061725	cytosolic lipolysis	biological_process	The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.
GO:0061726	mitochondrion disassembly	biological_process	The disaggregation of a mitochondrion into its constituent components.
GO:0061727	methylglyoxal catabolic process to lactate	biological_process	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.
GO:0061728	GDP-mannose biosynthetic process from mannose	biological_process	The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.
GO:0061729	GDP-mannose biosynthetic process from fructose-6-phosphate	biological_process	The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate.
GO:0061730	C-rich strand telomeric DNA binding	molecular_function	Binding to C-rich, single-stranded, telomere-associated DNA.
GO:0061731	ribonucleoside-diphosphate reductase activity	molecular_function	Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
GO:0061733	peptide-lysine-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological_process	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.
GO:0061735	DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological_process	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule.
GO:0061736	engulfment of target by autophagosome	biological_process	The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.
GO:0061737	leukotriene signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by leukotriene binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0061738	late endosomal microautophagy	biological_process	The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.
GO:0061739	protein lipidation involved in autophagosome assembly	biological_process	The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.
GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	biological_process	The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.
GO:0061742	chaperone-mediated autophagy translocation complex	cellular_component	A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.
GO:0061743	motor learning	biological_process	Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.
GO:0061744	motor behavior	biological_process	The specific neuromuscular movement of a single organism in response to external or internal stimuli.
GO:0061749	forked DNA-dependent helicase activity	molecular_function	Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.
GO:0061750	acid sphingomyelin phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment.
GO:0061751	neutral sphingomyelin phosphodiesterase activity	molecular_function	Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in a neutral environment.
GO:0061752	telomeric repeat-containing RNA binding	molecular_function	Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.
GO:0061753	substrate localization to autophagosome	biological_process	The localization process by which an autophagic substrate is delivered to a forming autophagosome.
GO:0061754	negative regulation of circulating fibrinogen levels	biological_process	Any process that reduces the quantity of fibrinogen circulating in the bloodstream.
GO:0061755	positive regulation of circulating fibrinogen levels	biological_process	Any process that increases the quantity of fibrinogen circulating in the bloodstream.
GO:0061756	leukocyte adhesion to vascular endothelial cell	biological_process	The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.
GO:0061757	leukocyte adhesion to arterial endothelial cell	biological_process	The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.
GO:0061758	2-hydroxyglutarate dehydrogenase activity, forward reaction	molecular_function	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.
GO:0061759	alpha-ketoglutarate reductase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + reduced acceptor = (S)-2-hydroxyglutarate + acceptor.
GO:0061760	antifungal innate immune response	biological_process	An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0061761	alpha-latrotoxin receptor binding	molecular_function	Binding to an alpha-latrotoxin receptor.
GO:0061762	CAMKK-AMPK signaling cascade	biological_process	The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.
GO:0061763	multivesicular body-lysosome fusion	biological_process	The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.
GO:0061764	late endosome to lysosome transport via multivesicular body sorting pathway	biological_process	The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
GO:0061765	perturbation by virus of host non-canonical NF-kappaB signal transduction	biological_process	A process in which a symbiont alters or subverts a non-canonical NF-kappaB signaling cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0061766	positive regulation of lung blood pressure	biological_process	The process that increases the force with which blood travels through the lungs.
GO:0061767	negative regulation of lung blood pressure	biological_process	The process that decreases the force with which blood travels through the lungs.
GO:0061768	magnesium:sodium antiporter activity	molecular_function	Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).
GO:0061769	ribosylnicotinate kinase activity	molecular_function	Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H+ + nicotinate mononucleotide.
GO:0061770	translation elongation factor binding	molecular_function	Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.
GO:0061771	response to caloric restriction	biological_process	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.
GO:0061772	xenobiotic transport across blood-nerve barrier	biological_process	The directed movement of a xenobiotic through the blood-nerve barrier.
GO:0061773	eNoSc complex	cellular_component	A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.
GO:0061774	cohesin unloading	biological_process	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.
GO:0061775	cohesin loader activity	molecular_function	Facilitating a conformational change to load a cohesin complex around sister chromatids.
GO:0061776	topological DNA co-entrapment activity	molecular_function	A DNA binding activity in which a protein complex interacts with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring.
GO:0061778	intracellular chloride channel activity	molecular_function	Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
GO:0061779	Tapasin-ERp57 complex	cellular_component	Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.
GO:0061780	mitotic cohesin loading	biological_process	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.
GO:0061781	mitotic cohesin unloading	biological_process	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.
GO:0061782	vesicle fusion with vesicle	biological_process	Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.
GO:0061783	peptidoglycan muralytic activity	molecular_function	A catalytic activity that contributes to the degradation of peptidoglycan.
GO:0061784	peptidoglycan N-acetylglucosaminidase activity	molecular_function	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.
GO:0061785	peptidoglycan endopeptidase activity	molecular_function	An endopeptidase activity that uses peptidoglycan as a substrate.
GO:0061786	peptidoglycan stem peptide endopeptidase activity	molecular_function	A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.
GO:0061787	peptidoglycan cross-bridge peptide endopeptidase activity	molecular_function	A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge.
GO:0061788	EGF repeat binding	molecular_function	Binding to Epidermal Growth Factor (EGF) repeats.
GO:0061789	dense core granule priming	biological_process	A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.
GO:0061790	dense core granule docking	biological_process	The initial attachment of a dense core granule membrane to the plasma membrane.
GO:0061791	GTPase motor activity	molecular_function	A motor activity driven by GTP hydrolysis.
GO:0061792	secretory granule maturation	biological_process	Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.
GO:0061793	chromatin lock complex	cellular_component	A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.
GO:0061794	conidium development	biological_process	The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
GO:0061795	Golgi lumen acidification	biological_process	Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.
GO:0061796	membrane addition at site of mitotic cytokinesis	biological_process	A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
GO:0061797	pH-gated chloride channel activity	molecular_function	A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.
GO:0061798	GTP 3',8'-cyclase activity	molecular_function	Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
GO:0061799	cyclic pyranopterin monophosphate synthase activity	molecular_function	Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.
GO:0061800	fibronectin fibril	cellular_component	A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.
GO:0061801	laminin-5B complex	cellular_component	A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.
GO:0061802	anterior cell cortex	cellular_component	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.
GO:0061803	posterior cell cortex	cellular_component	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.
GO:0061804	mitotic spindle formation (spindle phase one)	biological_process	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
GO:0061805	mitotic spindle elongation (spindle phase three)	biological_process	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.
GO:0061806	regulation of DNA recombination at centromere	biological_process	Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.
GO:0061807	positive regulation of DNA recombination at centromere	biological_process	Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.
GO:0061808	negative regulation of DNA recombination at centromere	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.
GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	molecular_function	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.
GO:0061810	NAD glycohydrolase activity	molecular_function	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate.
GO:0061811	ADP-ribosyl cyclase activity	molecular_function	Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide.
GO:0061812	cyclic ADP-ribose hydrolase	molecular_function	Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).
GO:0061815	Met1-linked polyubiquitin deubiquitinase activity	molecular_function	Catalysis of the hydrolysis of ubiquitin units from Met1-linked (or linear) polyubiquitin chains.
GO:0061816	proteaphagy	biological_process	The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.
GO:0061817	endoplasmic reticulum-plasma membrane tethering	biological_process	The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers.
GO:0061818	tRNA folding	biological_process	The process of assisting in the folding of tRNAs into the correct tertiary structure.
GO:0061819	telomeric DNA-containing double minutes formation	biological_process	A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.
GO:0061820	telomeric D-loop disassembly	biological_process	A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
GO:0061821	telomeric D-loop binding	molecular_function	Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
GO:0061822	ciliary cap	cellular_component	An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole.
GO:0061823	ring centriole	cellular_component	A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum.
GO:0061824	cytosolic ciliogenesis	biological_process	The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm.
GO:0061825	podosome core	cellular_component	The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.
GO:0061826	podosome ring	cellular_component	The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.
GO:0061827	sperm head	cellular_component	The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.
GO:0061828	apical tubulobulbar complex	cellular_component	Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.
GO:0061829	basal tubulobulbar complex	cellular_component	Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell.
GO:0061830	concave side of sperm head	cellular_component	The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.
GO:0061831	apical ectoplasmic specialization	cellular_component	Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.
GO:0061832	basal ectoplasmic specialization	cellular_component	Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.
GO:0061833	protein localization to tricellular tight junction	biological_process	A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction.
GO:0061834	actin filament branch point	cellular_component	The part of an actin filament where the structure forks.
GO:0061835	ventral surface of cell	cellular_component	The surface of a migrating cell that is in contact with the substratum or cell layer.
GO:0061836	intranuclear rod	cellular_component	A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions.
GO:0061837	neuropeptide processing	biological_process	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.
GO:0061838	CENP-T-W-S-X complex	cellular_component	A histone-variant containing protein complex which forms a centromere specific nucleosome-like structure, involved in centromeric chromatin organization.
GO:0061840	high-affinity ferrous iron transmembrane transporter activity	molecular_function	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0061841	high-affinity iron exporter complex	cellular_component	A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.
GO:0061842	microtubule organizing center localization	biological_process	Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.
GO:0061843	Sertoli cell barrier remodeling	biological_process	The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	biological_process	An immune response against microbes mediated by anti-microbial peptides in body fluid.
GO:0061845	neuron projection branch point	cellular_component	The location where a secondary projection arises from a neuron projection.
GO:0061846	dendritic spine cytoplasm	cellular_component	The region of the neuronal cytoplasm located in dendritic spines.
GO:0061847	response to cholecystokinin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.
GO:0061848	cellular response to cholecystokinin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.
GO:0061849	telomeric G-quadruplex DNA binding	molecular_function	Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.
GO:0061850	growth cone leading edge	cellular_component	That part of the growth cone which represents the distal part of the structure.
GO:0061851	leading edge of lamellipodium	cellular_component	That part of the lamellipodium which represents the distal part of the structure.
GO:0061852	retrograde transporter complex, Golgi to ER	cellular_component	Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles.
GO:0061853	regulation of neuroblast migration	biological_process	Any process that modulates the frequency, rate or extent of neuroblast migration.
GO:0061854	positive regulation of neuroblast migration	biological_process	Any process that activates or increases the frequency, rate or extent of neuroblast migration.
GO:0061855	negative regulation of neuroblast migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.
GO:0061856	Golgi calcium ion transmembrane transport	biological_process	A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.
GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control	biological_process	The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.
GO:0061860	DNA clamp unloader activity	molecular_function	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.
GO:0061862	cellular response to differentiation-inducing factor 2	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.
GO:0061863	microtubule plus end polymerase	molecular_function	Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.
GO:0061864	basement membrane constituent secretion	biological_process	The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell.
GO:0061865	polarized secretion of basement membrane proteins in epithelium	biological_process	The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium.
GO:0061867	establishment of mitotic spindle asymmetry	biological_process	The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.
GO:0061868	hepatic stellate cell migration	biological_process	The orderly movement of a hepatic stellate cell from one site to another.
GO:0061869	regulation of hepatic stellate cell migration	biological_process	Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.
GO:0061870	positive regulation of hepatic stellate cell migration	biological_process	Any process that increases the frequency, rate or extent of hepatic stellate cell migration.
GO:0061871	negative regulation of hepatic stellate cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.
GO:0061872	hepatic stellate cell contraction	biological_process	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.
GO:0061873	regulation of hepatic stellate cell contraction	biological_process	Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.
GO:0061874	positive regulation of hepatic stellate cell contraction	biological_process	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.
GO:0061875	negative regulation of hepatic stellate cell contraction	biological_process	Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction.
GO:0061880	regulation of anterograde axonal transport of mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
GO:0061881	positive regulation of anterograde axonal transport of mitochondrion	biological_process	Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
GO:0061882	negative regulation of anterograde axonal transport of mitochondrion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
GO:0061883	clathrin-dependent endocytosis involved in vitellogenesis	biological_process	A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition.
GO:0061884	regulation of mini excitatory postsynaptic potential	biological_process	Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.
GO:0061885	positive regulation of mini excitatory postsynaptic potential	biological_process	Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.
GO:0061886	negative regulation of mini excitatory postsynaptic potential	biological_process	Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.
GO:0061888	regulation of astrocyte activation	biological_process	Any process that modulates the frequency, rate or extent of astrocyte activation.
GO:0061889	negative regulation of astrocyte activation	biological_process	Any process that decreases the frequency, rate or extent of astrocyte activation.
GO:0061890	positive regulation of astrocyte activation	biological_process	Any process that increases the frequency, rate or extent of astrocyte activation.
GO:0061891	calcium ion sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).
GO:0061896	all-trans retinol 3,4-desaturase activity	molecular_function	Catalysis of the reaction: all-trans-retinol + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin].
GO:0061897	all-trans retinal 3,4-desaturase activity	molecular_function	Catalysis of the reaction: all-trans-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].
GO:0061898	all-trans retinoic acid 3,4-desaturase activity	molecular_function	Catalysis of the reaction: all-trans-retinoic acid + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].
GO:0061899	11-cis-retinal 3,4-desaturase activity	molecular_function	Catalysis of the reaction: 11-cis-retinal + 2 H+ + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].
GO:0061900	glial cell activation	biological_process	A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
GO:0061903	positive regulation of 1-phosphatidylinositol-3-kinase activity	biological_process	Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.
GO:0061906	autophagosome localization	biological_process	Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.
GO:0061907	negative regulation of AMPA receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.
GO:0061908	phagophore	cellular_component	A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.
GO:0061909	autophagosome-lysosome fusion	biological_process	The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.
GO:0061910	autophagosome-endosome fusion	biological_process	The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.
GO:0061911	amphisome-lysosome fusion	biological_process	The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome.
GO:0061912	selective autophagy	biological_process	The macroautophagy process in which specific structures are targeted by the autophagy process.
GO:0061913	positive regulation of growth plate cartilage chondrocyte proliferation	biological_process	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
GO:0061914	negative regulation of growth plate cartilage chondrocyte proliferation	biological_process	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
GO:0061916	leading edge of axonal growth cone	cellular_component	That part of the axonal growth cone which represents the distal part of the structure.
GO:0061917	leading edge of dendritic growth cone	cellular_component	That part of the dendritic growth cone which represents the distal part of the structure.
GO:0061919	process utilizing autophagic mechanism	biological_process	A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
GO:0061920	protein propionyltransferase activity	molecular_function	Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.
GO:0061921	peptidyl-lysine propionylation	biological_process	The propionylation of peptidyl-lysine.
GO:0061922	histone propionyltransferase activity	molecular_function	Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.
GO:0061923	(2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.
GO:0061924	regulation of formation of radial glial scaffolds	biological_process	Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.
GO:0061925	negative regulation of formation of radial glial scaffolds	biological_process	Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.
GO:0061926	positive regulation of formation of radial glial scaffolds	biological_process	Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds.
GO:0061927	TOC-TIC supercomplex I	cellular_component	The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110.
GO:0061928	glutathione specific gamma-glutamylcyclotransferase activity	molecular_function	Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.
GO:0061929	gamma-glutamylaminecyclotransferase activity	molecular_function	Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.
GO:0061930	regulation of erythrocyte enucleation	biological_process	Any process that modulates the frequency, rate or extent of erythrocyte enucleation.
GO:0061931	positive regulation of erythrocyte enucleation	biological_process	Any process that increases the frequency, rate or extent of erythrocyte enucleation.
GO:0061932	negative regulation of erythrocyte enucleation	biological_process	Any process that decreases the frequency, rate or extent of erythrocyte enucleation.
GO:0061934	regulation of adenine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.
GO:0061935	fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes	biological_process	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes.
GO:0061936	fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm	biological_process	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.
GO:0061938	protein localization to somatodendritic compartment	biological_process	A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.
GO:0061939	c-di-GMP signaling	biological_process	Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.
GO:0061940	regulation of c-di-GMP signaling	biological_process	Any process that modulates the rate frequency or extent of c-di-GMP signaling.
GO:0061941	positive regulation of c-di-GMP signaling	biological_process	Any process that increases the rate, frequency or extent of c-di-GMP signaling.
GO:0061942	negative regulation of c-di-GMP signaling	biological_process	Any process that decreases the rate, frequency or extent of c-di-GMP signaling.
GO:0061944	negative regulation of protein K48-linked ubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
GO:0061945	regulation of protein K48-linked ubiquitination	biological_process	Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
GO:0061948	premature acrosome loss	biological_process	The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.
GO:0061949	regulation of premature acrosome loss	biological_process	Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.
GO:0061950	negative regulation of premature acrosome loss	biological_process	Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.
GO:0061951	establishment of protein localization to plasma membrane	biological_process	The directed movement of a protein to a specific location in a plasma membrane.
GO:0061952	midbody abscission	biological_process	The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.
GO:0061953	mRNA (adenine-N1-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.
GO:0061956	penetration of cumulus oophorus	biological_process	The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
GO:0061957	NVT complex	cellular_component	A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1.
GO:0061959	response to (R)-carnitine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.
GO:0061960	regulation of heme oxygenase activity	biological_process	Any process that modulates the frequency, or rate of heme oxygenase activity.
GO:0061961	positive regulation of heme oxygenase activity	biological_process	Any process that activates or increases the frequency or rate of heme oxygenase activity.
GO:0061962	negative regulation of heme oxygenase activity	biological_process	Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity.
GO:0061963	regulation of entry into reproductive diapause	biological_process	Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0061964	negative regulation of entry into reproductive diapause	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0061965	positive regulation of entry into reproductive diapause	biological_process	Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0061966	establishment of left/right asymmetry	biological_process	The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.
GO:0061967	establishment of left sidedness	biological_process	The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.
GO:0061968	maintenance of left/right asymmetry	biological_process	The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.
GO:0061969	maintenance of left sidedness	biological_process	The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.
GO:0061970	maintenance of right sidedness	biological_process	The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.
GO:0061971	replacement bone morphogenesis	biological_process	The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.
GO:0061972	dermal bone morphogenesis	biological_process	The process in which bone which forms superficially in the organism are generated and organized.
GO:0061973	membrane bone morphogenesis	biological_process	The process in which bone which forms deep in the organism are generated and organized.
GO:0061974	perichondral bone morphogenesis	biological_process	The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.
GO:0061975	articular cartilage development	biological_process	The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.
GO:0061976	temporomandibular joint articular cartilage development	biological_process	The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.
GO:0061977	hip joint articular cartilage development	biological_process	The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.
GO:0061978	mandibular condyle articular cartilage development	biological_process	The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.
GO:0061979	femoral head articular cartilage development	biological_process	The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.
GO:0061980	regulatory RNA binding	molecular_function	Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.
GO:0061981	3-hydroxykynureninase activity	molecular_function	Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.
GO:0061982	meiosis I cell cycle process	biological_process	A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.
GO:0061983	meiosis II cell cycle process	biological_process	A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.
GO:0061984	catabolite repression	biological_process	A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.
GO:0061985	carbon catabolite repression	biological_process	A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.
GO:0061986	negative regulation of transcription by glucose	biological_process	Any process involving glucose that decreases the frequency, rate or extent or transcription.
GO:0061987	negative regulation of transcription from RNA polymerase II promoter by glucose	biological_process	Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.
GO:0061988	karyosome formation	biological_process	The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0061989	sperm karyosome formation	biological_process	The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0061990	beta-ketodecanoyl-[acyl-carrier-protein] synthase activity	molecular_function	Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.
GO:0061993	calcium:proton antiporter complex	cellular_component	A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
GO:0061995	ATP-dependent protein-DNA complex displacement activity	molecular_function	An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.
GO:0061999	regulation of cardiac endothelial to mesenchymal transition	biological_process	Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.
GO:0062000	positive regulation of cardiac endothelial to mesenchymal transition	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.
GO:0062001	negative regulation of cardiac endothelial to mesenchymal transition	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.
GO:0062002	regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	biological_process	Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.
GO:0062003	negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	biological_process	Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.
GO:0062009	secondary palate development	biological_process	The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
GO:0062010	primitive palate development	biological_process	The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.
GO:0062011	mitochondrial respiratory chain complex IV pre-assembly complex	cellular_component	A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.
GO:0062012	regulation of small molecule metabolic process	biological_process	Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
GO:0062013	positive regulation of small molecule metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
GO:0062014	negative regulation of small molecule metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
GO:0062021	mitotic cohesin dsDNA (leading strand) loading	biological_process	The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.
GO:0062022	mitotic cohesin ssDNA (lagging strand) loading	biological_process	The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.
GO:0062023	collagen-containing extracellular matrix	cellular_component	An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
GO:0062025	regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	biological_process	Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
GO:0062026	negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	biological_process	Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
GO:0062027	positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	biological_process	Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
GO:0062028	regulation of stress granule assembly	biological_process	Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
GO:0062029	positive regulation of stress granule assembly	biological_process	Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
GO:0062030	negative regulation of stress granule assembly	biological_process	Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
GO:0062031	filamentous growth MAPK cascade	biological_process	The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth.
GO:0062032	cichorine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.
GO:0062033	positive regulation of mitotic sister chromatid segregation	biological_process	Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.
GO:0062034	L-pipecolic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.
GO:0062035	sensory perception of cold stimulus	biological_process	The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GO:0062036	sensory perception of hot stimulus	biological_process	The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
GO:0062037	D-loop DNA binding	molecular_function	Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.
GO:0062038	positive regulation of pheromone response MAPK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.
GO:0062039	biofilm matrix	cellular_component	A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells.
GO:0062040	fungal biofilm matrix	cellular_component	An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
GO:0062041	positive regulation of meiotic sister chromatid arm separation	biological_process	Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
GO:0062042	regulation of cardiac epithelial to mesenchymal transition	biological_process	Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0062043	positive regulation of cardiac epithelial to mesenchymal transition	biological_process	Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0062044	negative regulation of cardiac epithelial to mesenchymal transition	biological_process	Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0062045	L-lysine alpha-aminotransferase	molecular_function	Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.
GO:0062046	dehydropipecolic acid reductase	molecular_function	Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.
GO:0062047	pipecolic acid N-hydroxylase	molecular_function	Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.
GO:0062048	lymphotoxin complex	cellular_component	A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.
GO:0062049	protein phosphatase inhibitor complex	cellular_component	A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.
GO:0062050	GPI-mannose ethanolamine phosphate phosphodiesterase activity	molecular_function	A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.
GO:0062051	lipopolysaccharide transport system	cellular_component	A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.
GO:0062052	starch granule initiation	biological_process	The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.
GO:0062054	fluoride channel activity	molecular_function	Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0062055	photosynthetic state transition	biological_process	A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.
GO:0062056	compound eye pigment cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.
GO:0062057	L-aspartate:fumarate antiporter activity	molecular_function	Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).
GO:0062058	transcription factor TFIIH holo complex binding	molecular_function	Binding to a transcription factor TFIIH holo complex.
GO:0062059	FACT complex binding	molecular_function	Binding to a FACT complex.
GO:0062060	NuA4 histone acetyltransferase complex binding	molecular_function	Binding to a NuA4 histone acetyltransferase complex.
GO:0062061	TAP complex binding	molecular_function	Binding to a TAP complex.
GO:0062062	oligosaccharyltransferase complex binding	molecular_function	Binding to an oligosaccharyltransferase complex.
GO:0062063	BBSome binding	molecular_function	Binding to a BBSome complex.
GO:0062064	box C/D snoRNP complex binding	molecular_function	Binding to a box C/D snoRNP complex.
GO:0062065	box H/ACA snoRNP complex binding	molecular_function	Binding to a box H/ACA snoRNP complex.
GO:0062066	PSII associated light-harvesting complex II binding	molecular_function	Binding to a PSII associated light-harvesting complex II.
GO:0062067	chloroplast photosystem I binding	molecular_function	Binding to a chloroplast photosystem I.
GO:0062068	chloroplast photosystem II binding	molecular_function	Binding to a chloroplast photosystem II.
GO:0062069	GARP complex binding	molecular_function	Binding to a GARP complex.
GO:0062070	SAGA complex binding	molecular_function	Binding to a SAGA complex.
GO:0062071	Pi Mi complex	cellular_component	A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.
GO:0062072	H3K9me3 modified histone binding	molecular_function	Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation.
GO:0062073	histone mRNA stem-loop binding complex	cellular_component	A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export.
GO:0062074	pollen aperture	cellular_component	An area where exine is reduced or absent, in the pollen wall.
GO:0062075	pollen aperture formation	biological_process	The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.
GO:0062076	acyl-CoA delta5-desaturase activity	molecular_function	Catalysis of the reaction: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA) and add a fourth double bond (a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA).
GO:0062077	phenylacetyl-CoA 1,2-epoxidase complex	cellular_component	A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.
GO:0062078	TSC1-TSC2 complex binding	molecular_function	Binding to a TSC1-TSC2 complex.
GO:0062079	ATG2-ATG18 complex	cellular_component	A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.
GO:0062080	inhibitory MHC class Ib receptor activity	molecular_function	Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.
GO:0062081	activating MHC class Ib receptor activity	molecular_function	Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.
GO:0062082	HLA-E specific inhibitory MHC class Ib receptor activity	molecular_function	Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
GO:0062083	HLA-G specific inhibitory MHC class Ib receptor activity	molecular_function	Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.
GO:0062084	regulation of capsule polysaccharide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0062085	positive regulation of capsule polysaccharide biosynthetic process	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
GO:0062086	regulation of vein smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.
GO:0062087	positive regulation of vein smooth muscle contraction	biological_process	Any process that increases the frequency, rate or extent of vein smooth muscle contraction.
GO:0062088	negative regulation of vein smooth muscle contraction	biological_process	Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.
GO:0062089	regulation of taurine biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of taurine biosynthesis.
GO:0062090	positive regulation of taurine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of taurine biosynthesis.
GO:0062091	Ycf2/FtsHi complex	cellular_component	A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.
GO:0062092	Yae1-Lto1 complex	cellular_component	A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.
GO:0062093	lysophagy	biological_process	The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.
GO:0062094	stomach development	biological_process	The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.
GO:0062095	endoplasmic reticulum-peroxisome tethering	biological_process	The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other.
GO:0062096	kinetochore disassembly	biological_process	The disaggregation of a kinetochore into its constituent components.
GO:0062097	chemosynthesis	biological_process	The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.
GO:0062098	regulation of programmed necrotic cell death	biological_process	Any process that modulates the frequency, rate or extent of programmed necrotic cell death.
GO:0062099	negative regulation of programmed necrotic cell death	biological_process	Any process that decreases the frequency, rate or extent of programmed necrotic cell death.
GO:0062100	positive regulation of programmed necrotic cell death	biological_process	Any process that increases the frequency, rate or extent of programmed necrotic cell death.
GO:0062101	peptidyl-aspartic acid 3-dioxygenase activity	molecular_function	Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.
GO:0062102	female germline stem cell symmetric division	biological_process	Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.
GO:0062104	pumilio-response element binding	molecular_function	Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.
GO:0062105	RNA 2'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.
GO:0062107	regulation of protein localization to non-growing cell tip	biological_process	Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.
GO:0062108	negative regulation of protein localization to non-growing cell tip	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.
GO:0062109	regulation of DNA recombinase disassembly	biological_process	Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.
GO:0062110	negative regulation of DNA recombinase disassembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.
GO:0062111	zinc ion import into organelle	biological_process	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.
GO:0062112	fatty acid primary amide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a fatty acid primary amide.
GO:0062113	early phagosome lumen	cellular_component	The volume enclosed by the membrane of an eary phagosome.
GO:0062116	phenyloplast	cellular_component	A chloroplast-derived plastid in which the solid form of phenol is stored.
GO:0062119	LinE complex	cellular_component	A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.
GO:0062120	LinE complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.
GO:0062121	linear element maturation	biological_process	The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.
GO:0062122	histone H3K37 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group to the lysine residue at position 37 of the histone H3 protein.
GO:0062123	regulation of linear element maturation	biological_process	Any process that modulates the rate, frequency or extent of linear element maturation.
GO:0062124	4-hydroxybutyrate receptor activity	molecular_function	Combining with 4-hydroxybutyrte to initiate a change in cell activity.
GO:0062125	regulation of mitochondrial gene expression	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
GO:0062126	fatty acid primary amide metabolic process	biological_process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.
GO:0062127	fatty acid primary amide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of primary fatty amides.
GO:0062128	MutSgamma complex	cellular_component	A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.
GO:0062129	chitin-based extracellular matrix	cellular_component	Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.
GO:0062130	adhesive extracellular matrix	cellular_component	A extracellular matrix which attaches an organism to a substrate.
GO:0062131	3-butenylglucosinolate 2-hydroxylase activity	molecular_function	Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.
GO:0062132	regulation of L-glutamine biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.
GO:0062133	negative regulation of L-glutamine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.
GO:0062134	positive regulation of L-glutamine biosynthetic process	biological_process	Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis.
GO:0062136	low-density lipoprotein receptor complex	cellular_component	A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.
GO:0062137	cargo receptor complex	cellular_component	Any protein complex that is part of a membrane and which functions as a cargo receptor.
GO:0062139	camera-type eye photoreceptor cell development	biological_process	The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.
GO:0062140	hyphae septin collar	cellular_component	A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.
GO:0062141	nuclear exosome targeting complex	cellular_component	A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.
GO:0062142	L-beta-ethynylserine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.
GO:0062143	L-propargylglycine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.
GO:0062144	L-propargylglycine synthase activity	molecular_function	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H+ + L-propargylglycine.
GO:0062145	L-propargylglycine--L-glutamate ligase activity	molecular_function	Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate.
GO:0062146	4-chloro-allylglycine synthase activity	molecular_function	Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+).
GO:0062147	L-lysine 4-chlorinase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.
GO:0062148	L-gamma-glutamyl-L-propargylglycine hydroxylase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.
GO:0062149	detection of stimulus involved in sensory perception of pain	biological_process	The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.
GO:0062150	amorpha-4,11-diene 12-monooxygenase activity	molecular_function	Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].
GO:0062151	catalase complex	cellular_component	A protein-containing complex that is capable of catalase activity.
GO:0062152	mRNA (cytidine-5-)-methyltransferase activity	molecular_function	Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.
GO:0062153	C5-methylcytidine-containing RNA binding	molecular_function	Binding to an RNA molecule modified by C5-methylcytidine.
GO:0062154	N6-methyl-AMP deaminase activity	molecular_function	Catalysis of the reaction: H+ + H2O + N6-methyl-AMP = IMP + methylamine. Can also use N6-methyl-dAMP as a substrate.
GO:0062155	curli secretion complex	cellular_component	A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms.
GO:0062156	mitochondrial ATP-gated potassium channel activity	molecular_function	Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.
GO:0062157	mitochondrial ATP-gated potassium channel complex	cellular_component	A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.
GO:0062158	chloride:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).
GO:0062159	contractile vacuole complex	cellular_component	A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.
GO:0062160	spongiome	cellular_component	A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.
GO:0062161	regulation of pyocyanine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.
GO:0062162	positive regulation of pyocyanine biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.
GO:0062163	pseudohyphal septin ring assembly	biological_process	The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.
GO:0062164	regulation of pseudohyphal septin ring assembly	biological_process	Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.
GO:0062165	positive regulation of pseudohyphal septin ring assembly	biological_process	Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.
GO:0062166	negative regulation of pseudohyphal septin ring assembly	biological_process	Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly.
GO:0062167	complement component C1q complex	cellular_component	A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.
GO:0062168	negative regulation of plus-end directed microtubule sliding	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.
GO:0062169	regulation of plus-end directed microtubule sliding	biological_process	Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.
GO:0062170	lutein metabolic process	biological_process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.
GO:0062171	lutein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lutein.
GO:0062172	lutein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lutein.
GO:0062173	brexanolone metabolic process	biological_process	The chemical reactions and pathways by which living organisms transform brexanolone.
GO:0062174	brexanolone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of brexanolone.
GO:0062175	brexanolone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of brexanolone.
GO:0062176	R-loop processing	biological_process	A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.
GO:0062177	radial spoke assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.
GO:0062179	vitamin D 23-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of C-23 of any form of vitamin D.
GO:0062180	25-hydroxycholecalciferol-23-hydroxylase activity	molecular_function	Catalysis of the reaction: calcidiol + 2 H+ + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].
GO:0062181	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	molecular_function	Catatlysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].
GO:0062182	all-trans retinoic acid 4-hydrolase activity	molecular_function	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0062183	all-trans retinoic acid 18-hydroxylase activity	molecular_function	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0062184	testosterone 16-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0062185	secalciferol 1-monooxygenase activity	molecular_function	Catalysis of the reaction:2 H+ + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].
GO:0062186	anandamide epoxidase activity	molecular_function	Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.
GO:0062187	anandamide 8,9 epoxidase activity	molecular_function	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
GO:0062188	anandamide 11,12 epoxidase activity	molecular_function	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
GO:0062189	anandamide 14,15 epoxidase activity	molecular_function	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
GO:0062191	galactoxylomannan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.
GO:0062192	L-rhamnose mutarotase activity	molecular_function	Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.
GO:0062193	D-ribose pyranase activity	molecular_function	Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose.
GO:0062194	cytoplasmic microtubule minus-end	cellular_component	A microtubule minus end that is part of a cytoplasmic microtubule.
GO:0062195	microtubule bundle maintenance	biological_process	The organization process that preserves a microtubule bundle in a stable functional or structural state.
GO:0062196	regulation of lysosome size	biological_process	Any process that modulates the size of a lysosome.
GO:0062197	cellular response to chemical stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.
GO:0062200	RAM/MOR signaling pathway	biological_process	An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase.
GO:0062201	actin wave	cellular_component	A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.
GO:0062202	Labd-13(16),14-diene-9-ol synthase activity	molecular_function	Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.
GO:0062203	Viteagnusin D synthase activity	molecular_function	Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.
GO:0062204	(13S)-vitexifolin A synthase activity	molecular_function	Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.
GO:0062205	miltiradiene synthase activity	molecular_function	Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene.
GO:0062206	manoyl oxide synthase activity	molecular_function	Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.
GO:0062207	regulation of pattern recognition receptor signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.
GO:0062209	spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	biological_process	Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.
GO:0062210	shoot regeneration	biological_process	The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.
GO:0062211	root regeneration	biological_process	The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.
GO:0062212	regulation of mitotic DNA replication initiation from early origin	biological_process	Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.
GO:0062213	peroxynitrite isomerase activity	molecular_function	Catalysis of the reaction: peroxynitrite = nitrate.
GO:0062223	regulation of somatic muscle development	biological_process	Any process that regulates the rate, frequency or extent of somatic muscle development.
GO:0062224	positive regulation of somatic muscle development	biological_process	Any process that increases the rate, frequency or extent of somatic muscle development.
GO:0062225	negative regulation of somatic muscle development	biological_process	Any process that decreases the rate, frequency or extent of somatic muscle development.
GO:0062226	regulation of adult somatic muscle development	biological_process	Any process that modulates the rate, frequency or extent of adult somatic muscle development.
GO:0062227	positive regulation of adult somatic muscle development	biological_process	Any process that increases the rate, frequency or extent of adult somatic muscle development.
GO:0062228	negative regulation of adult somatic muscle development	biological_process	Any process that decreases the rate, frequency or extent of adult somatic muscle development.
GO:0062229	regulation of larval somatic muscle development	biological_process	Any process that modulates the rate, frequency or extent of larval somatic muscle development.
GO:0062230	negative regulation of larval somatic muscle development	biological_process	Any process that decreases the rate, frequency or extent of larval somatic muscle development.
GO:0062231	positive regulation of larval somatic muscle development	biological_process	Any process that increases the rate, frequency or extent of larval somatic muscle development.
GO:0062232	prostanoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prostanoids.
GO:0062233	F2-isoprostane catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.
GO:0062234	platelet activating factor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.
GO:0062235	axonemal basal plate assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.
GO:0062236	ionocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.
GO:0062237	protein localization to postsynapse	biological_process	Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.
GO:0062238	Smp focus	cellular_component	A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.
GO:0062239	heterochromatin-nuclear membrane anchor activity	molecular_function	Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.
GO:0062240	euchromatin-nuclear membrane anchor activity	molecular_function	Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.
GO:0062241	double strand break-nuclear membrane anchor activity	molecular_function	Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.
GO:0062242	double membrane vesicle viral factory membrane	cellular_component	One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
GO:0062243	double membrane vesicle viral factory outer membrane	cellular_component	The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
GO:0062244	double membrane vesicle viral factory lumen	cellular_component	The volume surrounded by the inner membrane of a double membrane vesicle viral factory.
GO:0062245	double membrane vesicle viral factory inner membrane	cellular_component	The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
GO:0062246	exocytic vesicle lumen	cellular_component	The volume enclosed by an exocytic vesicle.
GO:0062247	chloroplast vesicle	cellular_component	A intracellular vesicle that is part of a chloroplast.
GO:0062248	cleistothecium formation	biological_process	The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
GO:0065001	specification of axis polarity	biological_process	The pattern specification process in which the polarity of a body or organ axis is established and maintained.
GO:0065002	intracellular protein transmembrane transport	biological_process	The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
GO:0065003	protein-containing complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
GO:0065004	protein-DNA complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.
GO:0065005	protein-lipid complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.
GO:0065007	biological regulation	biological_process	Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0065008	regulation of biological quality	biological_process	Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GO:0065009	regulation of molecular function	biological_process	Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0065010	extracellular membrane-bounded organelle	cellular_component	Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.
GO:0070001	aspartic-type peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
GO:0070002	glutamic-type peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
GO:0070003	threonine-type peptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
GO:0070004	cysteine-type exopeptidase activity	molecular_function	Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0070005	cysteine-type aminopeptidase activity	molecular_function	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0070006	metalloaminopeptidase activity	molecular_function	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0070007	glutamic-type endopeptidase activity	molecular_function	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
GO:0070008	serine-type exopeptidase activity	molecular_function	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0070009	serine-type aminopeptidase activity	molecular_function	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
GO:0070012	oligopeptidase activity	molecular_function	Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.
GO:0070013	intracellular organelle lumen	cellular_component	An organelle lumen that is part of an intracellular organelle.
GO:0070014	sucrase-isomaltase complex	cellular_component	A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.
GO:0070016	armadillo repeat domain binding	molecular_function	Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signaling and cytoskeletal regulation.
GO:0070017	alphav-beta3 integrin-thrombospondin complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.
GO:0070021	transforming growth factor beta ligand-receptor complex	cellular_component	A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.
GO:0070023	interleukin-12-interleukin-12 receptor complex	cellular_component	A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.
GO:0070024	CD19-Vav-PIK3R1 complex	cellular_component	A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).
GO:0070025	carbon monoxide binding	molecular_function	Binding to carbon monoxide (CO).
GO:0070026	nitric oxide binding	molecular_function	Binding to nitric oxide (NO).
GO:0070027	carbon monoxide sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).
GO:0070029	alphav-beta3 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.
GO:0070030	alphav-beta1 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.
GO:0070031	alphav-beta5 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.
GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).
GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).
GO:0070034	telomerase RNA binding	molecular_function	Binding to the telomerase RNA template.
GO:0070037	rRNA (pseudouridine) methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
GO:0070038	rRNA (pseudouridine-N3-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
GO:0070039	rRNA (guanosine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.
GO:0070040	rRNA (adenine-C2-)-methyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.
GO:0070041	rRNA (uridine-C5-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
GO:0070042	rRNA (uridine-N3-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.
GO:0070043	rRNA (guanine-N7-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).
GO:0070045	synaptobrevin 2-SNAP-25-syntaxin-2 complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).
GO:0070046	synaptobrevin 2-SNAP-25-syntaxin-3 complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).
GO:0070047	synaptobrevin 2-SNAP-25-syntaxin-4 complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).
GO:0070048	endobrevin-SNAP-25-syntaxin-1a complex	cellular_component	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).
GO:0070049	endobrevin-SNAP-25-syntaxin-2 complex	cellular_component	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).
GO:0070050	neuron cellular homeostasis	biological_process	The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.
GO:0070051	fibrinogen binding	molecular_function	Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
GO:0070052	collagen V binding	molecular_function	Binding to a type V collagen trimer.
GO:0070053	thrombospondin receptor activity	molecular_function	Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.
GO:0070054	mRNA splicing, via endonucleolytic cleavage and ligation	biological_process	Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
GO:0070056	prospore membrane leading edge	cellular_component	The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.
GO:0070057	prospore membrane spindle pole body attachment site	cellular_component	The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.
GO:0070058	tRNA gene clustering	biological_process	The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GO:0070060	'de novo' actin filament nucleation	biological_process	The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.
GO:0070061	fructose binding	molecular_function	Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
GO:0070062	extracellular exosome	cellular_component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
GO:0070063	RNA polymerase binding	molecular_function	Binding to an RNA polymerase molecule or complex.
GO:0070064	proline-rich region binding	molecular_function	Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.
GO:0070065	cellubrevin-VAMP4-syntaxin-16 complex	cellular_component	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).
GO:0070066	cellubrevin-VAMP4-endobrevin-syntaxin-6 complex	cellular_component	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).
GO:0070067	syntaxin-6-syntaxin-16-Vti1a complex	cellular_component	A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
GO:0070068	VAMP4-syntaxin-6-syntaxin-16-Vti1a complex	cellular_component	A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
GO:0070069	cytochrome complex	cellular_component	A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
GO:0070070	proton-transporting V-type ATPase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.
GO:0070071	proton-transporting two-sector ATPase complex assembly	biological_process	The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	biological_process	The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
GO:0070073	clustering of voltage-gated calcium channels	biological_process	The process in which voltage-gated calcium channels become localized together in high densities.
GO:0070074	mononeme	cellular_component	A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.
GO:0070075	tear secretion	biological_process	The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.
GO:0070076	histone lysine demethylation	biological_process	The modification of a histone by the removal of a methyl group from a lysine residue.
GO:0070078	histone H3-R2 demethylation	biological_process	The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.
GO:0070079	histone H4-R3 demethylation	biological_process	The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.
GO:0070080	titin Z domain binding	molecular_function	Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
GO:0070081	clathrin-sculpted monoamine transport vesicle	cellular_component	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.
GO:0070082	clathrin-sculpted monoamine transport vesicle lumen	cellular_component	The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.
GO:0070083	clathrin-sculpted monoamine transport vesicle membrane	cellular_component	The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.
GO:0070085	glycosylation	biological_process	The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
GO:0070086	ubiquitin-dependent endocytosis	biological_process	Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
GO:0070087	chromo shadow domain binding	molecular_function	Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.
GO:0070088	polyhydroxyalkanoate granule	cellular_component	An inclusion body located in the cytoplasm of prokaryotes that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.
GO:0070089	chloride-activated potassium channel activity	molecular_function	Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
GO:0070090	metaphase plate	cellular_component	The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
GO:0070091	glucagon secretion	biological_process	The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).
GO:0070092	regulation of glucagon secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of glucagon.
GO:0070093	negative regulation of glucagon secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.
GO:0070094	positive regulation of glucagon secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.
GO:0070095	fructose-6-phosphate binding	molecular_function	Binding to fructose 6-phosphate.
GO:0070096	mitochondrial outer membrane translocase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.
GO:0070097	delta-catenin binding	molecular_function	Binding to the delta subunit of the catenin complex.
GO:0070098	chemokine-mediated signaling pathway	biological_process	The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070099	regulation of chemokine-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway.
GO:0070100	negative regulation of chemokine-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway.
GO:0070101	positive regulation of chemokine-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway.
GO:0070102	interleukin-6-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070103	regulation of interleukin-6-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
GO:0070104	negative regulation of interleukin-6-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
GO:0070106	interleukin-27-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070107	regulation of interleukin-27-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
GO:0070108	negative regulation of interleukin-27-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
GO:0070109	positive regulation of interleukin-27-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
GO:0070110	ciliary neurotrophic factor receptor complex	cellular_component	A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.
GO:0070111	organellar chromatophore	cellular_component	A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.
GO:0070112	organellar chromatophore membrane	cellular_component	Either of the lipid bilayers that surround an organellar chromatophore.
GO:0070113	organellar chromatophore inner membrane	cellular_component	The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.
GO:0070114	organellar chromatophore outer membrane	cellular_component	The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.
GO:0070115	organellar chromatophore intermembrane space	cellular_component	The region between the inner and outer lipid bilayers that surround an organellar chromatophore.
GO:0070116	organellar chromatophore thylakoid	cellular_component	A thylakoid located in an organellar chromatophore.
GO:0070117	organellar chromatophore thylakoid lumen	cellular_component	The volume enclosed by an organellar chromatophore thylakoid membrane.
GO:0070118	organellar chromatophore thylakoid membrane	cellular_component	The lipid bilayer membrane of any thylakoid within an organellar chromatophore.
GO:0070119	ciliary neurotrophic factor binding	molecular_function	Binding to the cytokine ciliary neurotrophic factor.
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070121	Kupffer's vesicle development	biological_process	The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
GO:0070123	transforming growth factor beta receptor activity, type III	molecular_function	Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.
GO:0070124	mitochondrial translational initiation	biological_process	The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GO:0070125	mitochondrial translational elongation	biological_process	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
GO:0070126	mitochondrial translational termination	biological_process	The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	biological_process	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
GO:0070129	regulation of mitochondrial translation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GO:0070130	negative regulation of mitochondrial translation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GO:0070131	positive regulation of mitochondrial translation	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GO:0070132	regulation of mitochondrial translational initiation	biological_process	Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GO:0070133	negative regulation of mitochondrial translational initiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GO:0070134	positive regulation of mitochondrial translational initiation	biological_process	Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GO:0070135	beta-1,2-oligomannoside metabolic process	biological_process	The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
GO:0070136	beta-1,2-oligomannoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
GO:0070137	ubiquitin-like protein-specific endopeptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).
GO:0070139	SUMO-specific endopeptidase activity	molecular_function	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.
GO:0070141	response to UV-A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
GO:0070142	synaptic vesicle budding	biological_process	Evagination of a membrane to form a synaptic vesicle.
GO:0070143	mitochondrial alanyl-tRNA aminoacylation	biological_process	The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070144	mitochondrial arginyl-tRNA aminoacylation	biological_process	The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	biological_process	The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070146	mitochondrial aspartyl-tRNA aminoacylation	biological_process	The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070147	mitochondrial cysteinyl-tRNA aminoacylation	biological_process	The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070148	mitochondrial glutaminyl-tRNA aminoacylation	biological_process	The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070149	mitochondrial glutamyl-tRNA aminoacylation	biological_process	The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070150	mitochondrial glycyl-tRNA aminoacylation	biological_process	The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070151	mitochondrial histidyl-tRNA aminoacylation	biological_process	The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070152	mitochondrial isoleucyl-tRNA aminoacylation	biological_process	The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070153	mitochondrial leucyl-tRNA aminoacylation	biological_process	The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070154	mitochondrial lysyl-tRNA aminoacylation	biological_process	The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070155	mitochondrial methionyl-tRNA aminoacylation	biological_process	The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070156	mitochondrial phenylalanyl-tRNA aminoacylation	biological_process	The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070157	mitochondrial prolyl-tRNA aminoacylation	biological_process	The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070158	mitochondrial seryl-tRNA aminoacylation	biological_process	The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	biological_process	The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070160	tight junction	cellular_component	A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
GO:0070161	anchoring junction	cellular_component	A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
GO:0070162	adiponectin secretion	biological_process	The regulated release of adiponectin, a protein hormone, by adipose tissue.
GO:0070163	regulation of adiponectin secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.
GO:0070164	negative regulation of adiponectin secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.
GO:0070165	positive regulation of adiponectin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.
GO:0070166	enamel mineralization	biological_process	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
GO:0070167	regulation of biomineral tissue development	biological_process	Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
GO:0070168	negative regulation of biomineral tissue development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
GO:0070169	positive regulation of biomineral tissue development	biological_process	Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
GO:0070170	regulation of tooth mineralization	biological_process	Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
GO:0070171	negative regulation of tooth mineralization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
GO:0070172	positive regulation of tooth mineralization	biological_process	Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
GO:0070173	regulation of enamel mineralization	biological_process	Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
GO:0070174	negative regulation of enamel mineralization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
GO:0070175	positive regulation of enamel mineralization	biological_process	Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
GO:0070176	DRM complex	cellular_component	A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.
GO:0070177	contractile vacuole discharge	biological_process	The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.
GO:0070178	D-serine metabolic process	biological_process	The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.
GO:0070179	D-serine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.
GO:0070180	large ribosomal subunit rRNA binding	molecular_function	Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
GO:0070181	small ribosomal subunit rRNA binding	molecular_function	Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.
GO:0070182	DNA polymerase binding	molecular_function	Binding to a DNA polymerase.
GO:0070183	mitochondrial tryptophanyl-tRNA aminoacylation	biological_process	The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070184	mitochondrial tyrosyl-tRNA aminoacylation	biological_process	The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070185	mitochondrial valyl-tRNA aminoacylation	biological_process	The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
GO:0070186	growth hormone activity	molecular_function	The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.
GO:0070187	shelterin complex	cellular_component	A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.
GO:0070189	kynurenine metabolic process	biological_process	The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
GO:0070192	chromosome organization involved in meiotic cell cycle	biological_process	A process of chromosome organization that is involved in a meiotic cell cycle.
GO:0070193	synaptonemal complex organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.
GO:0070194	synaptonemal complex disassembly	biological_process	The controlled breakdown of a synaptonemal complex.
GO:0070195	growth hormone receptor complex	cellular_component	A receptor complex that consists of two identical subunits and binds growth hormone.
GO:0070196	eukaryotic translation initiation factor 3 complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.
GO:0070197	meiotic attachment of telomere to nuclear envelope	biological_process	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.
GO:0070198	protein localization to chromosome, telomeric region	biological_process	Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
GO:0070199	establishment of protein localization to chromosome	biological_process	The directed movement of a protein to a specific location on a chromosome.
GO:0070200	establishment of protein localization to telomere	biological_process	The directed movement of a protein to a specific location in the telomeric region of a chromosome.
GO:0070201	regulation of establishment of protein localization	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
GO:0070202	regulation of establishment of protein localization to chromosome	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
GO:0070203	regulation of establishment of protein localization to telomere	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.
GO:0070204	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + H+ + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2.
GO:0070205	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	molecular_function	Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.
GO:0070206	protein trimerization	biological_process	The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
GO:0070207	protein homotrimerization	biological_process	The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
GO:0070208	protein heterotrimerization	biological_process	The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.
GO:0070209	ASTRA complex	cellular_component	A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.
GO:0070210	Rpd3L-Expanded complex	cellular_component	A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.
GO:0070211	Snt2C complex	cellular_component	A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.
GO:0070212	protein poly-ADP-ribosylation	biological_process	The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
GO:0070213	protein auto-ADP-ribosylation	biological_process	The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
GO:0070214	CSK-GAP-A.p62 complex	cellular_component	A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.
GO:0070217	transcription factor TFIIIB complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.
GO:0070220	aerobic sulfur oxidation	biological_process	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.
GO:0070221	sulfide oxidation, using sulfide:quinone oxidoreductase	biological_process	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.
GO:0070222	sulfide oxidation, using sulfide dehydrogenase	biological_process	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.
GO:0070223	sulfide oxidation, using sulfur dioxygenase	biological_process	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.
GO:0070224	sulfide:quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.
GO:0070225	sulfide dehydrogenase activity	molecular_function	Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.
GO:0070226	sulfur:ferric ion oxidoreductase activity	molecular_function	Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.
GO:0070227	lymphocyte apoptotic process	biological_process	Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0070228	regulation of lymphocyte apoptotic process	biological_process	Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.
GO:0070229	negative regulation of lymphocyte apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.
GO:0070230	positive regulation of lymphocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.
GO:0070231	T cell apoptotic process	biological_process	Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
GO:0070232	regulation of T cell apoptotic process	biological_process	Any process that modulates the occurrence or rate of T cell death by apoptotic process.
GO:0070233	negative regulation of T cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.
GO:0070234	positive regulation of T cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.
GO:0070235	regulation of activation-induced cell death of T cells	biological_process	Any process that modulates the occurrence or rate of activation-induced cell death of T cells.
GO:0070236	negative regulation of activation-induced cell death of T cells	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.
GO:0070237	positive regulation of activation-induced cell death of T cells	biological_process	Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.
GO:0070238	activated T cell autonomous cell death	biological_process	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.
GO:0070239	regulation of activated T cell autonomous cell death	biological_process	Any process that modulates the occurrence or rate of activated T cell autonomous cell death.
GO:0070240	negative regulation of activated T cell autonomous cell death	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.
GO:0070241	positive regulation of activated T cell autonomous cell death	biological_process	Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.
GO:0070242	thymocyte apoptotic process	biological_process	Any apoptotic process in a thymocyte, an immature T cell located in the thymus.
GO:0070243	regulation of thymocyte apoptotic process	biological_process	Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.
GO:0070244	negative regulation of thymocyte apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.
GO:0070245	positive regulation of thymocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.
GO:0070246	natural killer cell apoptotic process	biological_process	Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.
GO:0070247	regulation of natural killer cell apoptotic process	biological_process	Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.
GO:0070248	negative regulation of natural killer cell apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.
GO:0070249	positive regulation of natural killer cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.
GO:0070250	mating projection membrane	cellular_component	The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.
GO:0070251	pristanate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.
GO:0070252	actin-mediated cell contraction	biological_process	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
GO:0070253	somatostatin secretion	biological_process	The regulated release of somatostatin from secretory granules in the D cells of the pancreas.
GO:0070254	mucus secretion	biological_process	The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.
GO:0070255	regulation of mucus secretion	biological_process	Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
GO:0070256	negative regulation of mucus secretion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
GO:0070257	positive regulation of mucus secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
GO:0070258	inner membrane pellicle complex	cellular_component	A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.
GO:0070259	tyrosyl-DNA phosphodiesterase activity	molecular_function	Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.
GO:0070260	5'-tyrosyl-DNA phosphodiesterase activity	molecular_function	Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.
GO:0070262	peptidyl-serine dephosphorylation	biological_process	The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.
GO:0070263	external side of fungal-type cell wall	cellular_component	The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.
GO:0070264	transcription factor TFIIIE complex	cellular_component	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.
GO:0070266	necroptotic process	biological_process	A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.
GO:0070268	cornification	biological_process	A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
GO:0070269	pyroptosis	biological_process	A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.
GO:0070273	phosphatidylinositol-4-phosphate binding	molecular_function	Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
GO:0070274	RES complex	cellular_component	A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.
GO:0070275	aerobic ammonia oxidation to nitrite via pyruvic oxime	biological_process	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.
GO:0070276	halogen metabolic process	biological_process	The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.
GO:0070277	iodide oxidation	biological_process	The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.
GO:0070278	extracellular matrix constituent secretion	biological_process	The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.
GO:0070279	vitamin B6 binding	molecular_function	Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.
GO:0070280	pyridoxal binding	molecular_function	Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.
GO:0070281	pyridoxamine binding	molecular_function	Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
GO:0070282	pyridoxine binding	molecular_function	Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
GO:0070284	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity	molecular_function	Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine.
GO:0070285	pigment cell development	biological_process	The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.
GO:0070286	axonemal dynein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
GO:0070287	ferritin receptor activity	molecular_function	Combining with ferritin, and delivering ferritin into the cell via endocytosis.
GO:0070288	ferritin complex	cellular_component	A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.
GO:0070289	extracellular ferritin complex	cellular_component	A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.
GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity	molecular_function	Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).
GO:0070291	N-acylethanolamine metabolic process	biological_process	The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.
GO:0070292	N-acylphosphatidylethanolamine metabolic process	biological_process	The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.
GO:0070293	renal absorption	biological_process	A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).
GO:0070294	renal sodium ion absorption	biological_process	A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
GO:0070295	renal water absorption	biological_process	A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
GO:0070296	sarcoplasmic reticulum calcium ion transport	biological_process	The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.
GO:0070297	regulation of phosphorelay signal transduction system	biological_process	Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
GO:0070298	negative regulation of phosphorelay signal transduction system	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
GO:0070299	positive regulation of phosphorelay signal transduction system	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
GO:0070300	phosphatidic acid binding	molecular_function	Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
GO:0070301	cellular response to hydrogen peroxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
GO:0070302	regulation of stress-activated protein kinase signaling cascade	biological_process	Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
GO:0070305	response to cGMP	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.
GO:0070306	lens fiber cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
GO:0070307	lens fiber cell development	biological_process	The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
GO:0070308	lens fiber cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
GO:0070309	lens fiber cell morphogenesis	biological_process	The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
GO:0070310	ATR-ATRIP complex	cellular_component	A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.
GO:0070311	nucleosomal methylation activator complex	cellular_component	A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.
GO:0070312	RAD52-ERCC4-ERCC1 complex	cellular_component	A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.
GO:0070313	RGS6-DNMT1-DMAP1 complex	cellular_component	A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.
GO:0070314	G1 to G0 transition	biological_process	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.
GO:0070315	G1 to G0 transition involved in cell differentiation	biological_process	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.
GO:0070316	regulation of G0 to G1 transition	biological_process	A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.
GO:0070317	negative regulation of G0 to G1 transition	biological_process	A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
GO:0070318	positive regulation of G0 to G1 transition	biological_process	A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.
GO:0070319	Golgi to plasma membrane transport vesicle	cellular_component	A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.
GO:0070320	inward rectifier potassium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.
GO:0070324	thyroid hormone binding	molecular_function	Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
GO:0070325	lipoprotein particle receptor binding	molecular_function	Binding to a lipoprotein particle receptor.
GO:0070326	very-low-density lipoprotein particle receptor binding	molecular_function	Binding to a very-low-density lipoprotein receptor.
GO:0070327	thyroid hormone transport	biological_process	The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0070328	triglyceride homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
GO:0070329	tRNA seleno-modification	biological_process	The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.
GO:0070330	aromatase activity	molecular_function	Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.
GO:0070331	CD20-Lck-Fyn complex	cellular_component	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.
GO:0070332	CD20-Lck-Lyn-Fyn complex	cellular_component	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.
GO:0070333	alpha6-beta4 integrin-Shc-Grb2 complex	cellular_component	A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.
GO:0070334	alpha6-beta4 integrin-laminin 5 complex	cellular_component	A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.
GO:0070335	aspartate binding	molecular_function	Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.
GO:0070336	flap-structured DNA binding	molecular_function	Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.
GO:0070337	3'-flap-structured DNA binding	molecular_function	Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.
GO:0070338	5'-flap-structured DNA binding	molecular_function	Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.
GO:0070339	response to bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
GO:0070340	detection of bacterial lipopeptide	biological_process	The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.
GO:0070341	fat cell proliferation	biological_process	The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.
GO:0070342	brown fat cell proliferation	biological_process	The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.
GO:0070343	white fat cell proliferation	biological_process	The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.
GO:0070344	regulation of fat cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of fat cell proliferation.
GO:0070345	negative regulation of fat cell proliferation	biological_process	Any process that stops or decreases the rate or extent of fat cell proliferation.
GO:0070346	positive regulation of fat cell proliferation	biological_process	Any process that activates or increases the rate or extent of fat cell proliferation.
GO:0070347	regulation of brown fat cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of brown fat cell proliferation.
GO:0070348	negative regulation of brown fat cell proliferation	biological_process	Any process that stops or decreases the rate or extent of brown fat cell proliferation.
GO:0070349	positive regulation of brown fat cell proliferation	biological_process	Any process that activates or increases the rate or extent of brown fat cell proliferation.
GO:0070350	regulation of white fat cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of white fat cell proliferation.
GO:0070351	negative regulation of white fat cell proliferation	biological_process	Any process that stops or decreases the rate or extent of white fat cell proliferation.
GO:0070352	positive regulation of white fat cell proliferation	biological_process	Any process that activates or increases the rate or extent of white fat cell proliferation.
GO:0070353	GATA1-TAL1-TCF3-Lmo2 complex	cellular_component	A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
GO:0070354	GATA2-TAL1-TCF3-Lmo2 complex	cellular_component	A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
GO:0070355	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex	cellular_component	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).
GO:0070356	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex	cellular_component	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).
GO:0070357	alphav-beta3 integrin-CD47 complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).
GO:0070358	actin polymerization-dependent cell motility	biological_process	A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
GO:0070360	actin polymerization-dependent cell migration in host	biological_process	The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0070365	hepatocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.
GO:0070366	regulation of hepatocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of hepatocyte differentiation.
GO:0070367	negative regulation of hepatocyte differentiation	biological_process	Any process that stops or decreases the rate or extent of hepatocyte differentiation.
GO:0070368	positive regulation of hepatocyte differentiation	biological_process	Any process that activates or increases the rate or extent of hepatocyte differentiation.
GO:0070369	beta-catenin-TCF7L2 complex	cellular_component	A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
GO:0070370	cellular heat acclimation	biological_process	Any process that increases heat tolerance of a cell in response to high temperatures.
GO:0070371	ERK1 and ERK2 cascade	biological_process	An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
GO:0070372	regulation of ERK1 and ERK2 cascade	biological_process	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
GO:0070373	negative regulation of ERK1 and ERK2 cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
GO:0070374	positive regulation of ERK1 and ERK2 cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
GO:0070375	ERK5 cascade	biological_process	An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
GO:0070376	regulation of ERK5 cascade	biological_process	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
GO:0070377	negative regulation of ERK5 cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
GO:0070378	positive regulation of ERK5 cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
GO:0070379	high mobility group box 1 binding	molecular_function	Binding to high mobility group box 1 (HMBGB1).
GO:0070380	high mobility group box 1 receptor activity	molecular_function	Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0070381	endosome to plasma membrane transport vesicle	cellular_component	A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis.
GO:0070382	exocytic vesicle	cellular_component	A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.
GO:0070383	DNA cytosine deamination	biological_process	The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
GO:0070384	Harderian gland development	biological_process	The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.
GO:0070385	egasyn-beta-glucuronidase complex	cellular_component	A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.
GO:0070386	procollagen-proline 4-dioxygenase complex, alpha(I) type	cellular_component	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).
GO:0070387	procollagen-proline 4-dioxygenase complex, alpha(II) type	cellular_component	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.
GO:0070388	procollagen-proline 4-dioxygenase complex, alpha(III) type	cellular_component	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.
GO:0070390	transcription export complex 2	cellular_component	A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
GO:0070391	response to lipoteichoic acid	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0070392	detection of lipoteichoic acid	biological_process	The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0070393	teichoic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.
GO:0070394	lipoteichoic acid metabolic process	biological_process	The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0070395	lipoteichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0070396	lipoteichoic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0070397	wall teichoic acid metabolic process	biological_process	The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
GO:0070398	wall teichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
GO:0070399	wall teichoic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
GO:0070400	teichoic acid D-alanylation	biological_process	The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.
GO:0070401	NADP+ binding	molecular_function	Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
GO:0070402	NADPH binding	molecular_function	Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
GO:0070403	NAD+ binding	molecular_function	Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
GO:0070404	NADH binding	molecular_function	Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
GO:0070405	ammonium ion binding	molecular_function	Binding to ammonium ions (NH4+).
GO:0070406	glutamine binding	molecular_function	Binding to glutamine, 2,5-diamino-5-oxopentanoic acid.
GO:0070407	oxidation-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.
GO:0070408	carbamoyl phosphate metabolic process	biological_process	The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
GO:0070409	carbamoyl phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
GO:0070410	co-SMAD binding	molecular_function	Binding to a common mediator SMAD signaling protein.
GO:0070411	I-SMAD binding	molecular_function	Binding to an inhibitory SMAD signaling protein.
GO:0070412	R-SMAD binding	molecular_function	Binding to a receptor-regulated SMAD signaling protein.
GO:0070413	trehalose metabolism in response to stress	biological_process	The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.
GO:0070414	trehalose metabolism in response to heat stress	biological_process	The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0070415	trehalose metabolism in response to cold stress	biological_process	The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
GO:0070416	trehalose metabolism in response to water deprivation	biological_process	The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.
GO:0070417	cellular response to cold	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
GO:0070418	DNA-dependent protein kinase complex	cellular_component	A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.
GO:0070419	nonhomologous end joining complex	cellular_component	A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.
GO:0070420	Ku-DNA ligase complex	cellular_component	A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.
GO:0070421	DNA ligase III-XRCC1 complex	cellular_component	A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.
GO:0070422	G-protein beta/gamma-Raf-1 complex	cellular_component	A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing (NOD) protein receptor, and ending with regulation of a downstream cellular process.
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.
GO:0070425	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.
GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 1 (NOD1) protein receptor, and ending with regulation of a downstream cellular process.
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	biological_process	The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	biological_process	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	biological_process	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
GO:0070435	Shc-EGFR complex	cellular_component	A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070436	Grb2-EGFR complex	cellular_component	A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070437	Grb2-Shc complex	cellular_component	A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.
GO:0070439	Mad-Max-mSin3A complex	cellular_component	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.
GO:0070440	Mad-Max-mSin3B complex	cellular_component	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.
GO:0070441	G-protein beta/gamma-Btk complex	cellular_component	A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.
GO:0070442	integrin alphaIIb-beta3 complex	cellular_component	An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.
GO:0070443	Mad-Max complex	cellular_component	A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.
GO:0070444	oligodendrocyte progenitor proliferation	biological_process	The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.
GO:0070445	regulation of oligodendrocyte progenitor proliferation	biological_process	Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.
GO:0070446	negative regulation of oligodendrocyte progenitor proliferation	biological_process	Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.
GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	biological_process	Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.
GO:0070448	laricitrin 5'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.
GO:0070449	elongin complex	cellular_component	A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.
GO:0070450	interleukin4-interleukin-4 receptor complex	cellular_component	A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.
GO:0070451	cell hair	cellular_component	A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.
GO:0070452	positive regulation of ergosterol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
GO:0070453	regulation of heme biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
GO:0070454	negative regulation of heme biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
GO:0070455	positive regulation of heme biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
GO:0070456	galactose-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.
GO:0070457	D-galactose-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.
GO:0070458	cellular detoxification of nitrogen compound	biological_process	Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
GO:0070459	prolactin secretion	biological_process	The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
GO:0070460	thyroid-stimulating hormone secretion	biological_process	The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.
GO:0070461	SAGA-type complex	cellular_component	A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).
GO:0070462	plus-end specific microtubule depolymerization	biological_process	The removal of tubulin heterodimers from the plus end of a microtubule.
GO:0070463	tubulin-dependent ATPase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.
GO:0070464	alphav-beta3 integrin-collagen alpha3(VI) complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.
GO:0070465	alpha1-beta1 integrin-alpha3(VI) complex	cellular_component	A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
GO:0070466	alpha2-beta1 integrin-alpha3(VI) complex	cellular_component	A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
GO:0070467	RC-1 DNA recombination complex	cellular_component	A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.
GO:0070468	dentin extracellular matrix secretion	biological_process	The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.
GO:0070469	respirasome	cellular_component	The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
GO:0070470	plasma membrane respirasome	cellular_component	A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
GO:0070471	uterine smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.
GO:0070472	regulation of uterine smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.
GO:0070473	negative regulation of uterine smooth muscle contraction	biological_process	Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.
GO:0070474	positive regulation of uterine smooth muscle contraction	biological_process	Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.
GO:0070475	rRNA base methylation	biological_process	The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
GO:0070476	rRNA (guanine-N7)-methylation	biological_process	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
GO:0070477	endospore core	cellular_component	An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.
GO:0070478	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	biological_process	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
GO:0070479	nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay	biological_process	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.
GO:0070480	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay	biological_process	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.
GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay	biological_process	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
GO:0070482	response to oxygen levels	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
GO:0070483	detection of hypoxia	biological_process	The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
GO:0070484	dehydro-D-arabinono-1,4-lactone metabolic process	biological_process	The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
GO:0070485	dehydro-D-arabinono-1,4-lactone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
GO:0070486	leukocyte aggregation	biological_process	The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.
GO:0070487	monocyte aggregation	biological_process	The adhesion of one monocyte to one or more other monocytes via adhesion molecules.
GO:0070488	neutrophil aggregation	biological_process	The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.
GO:0070489	T cell aggregation	biological_process	The adhesion of one T cell to one or more other T cells via adhesion molecules.
GO:0070490	protein pupylation	biological_process	The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.
GO:0070492	oligosaccharide binding	molecular_function	Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
GO:0070493	thrombin-activated receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0070494	regulation of thrombin-activated receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
GO:0070495	negative regulation of thrombin-activated receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
GO:0070496	positive regulation of thrombin-activated receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
GO:0070497	6-carboxy-5,6,7,8-tetrahydropterin synthase activity	molecular_function	Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.
GO:0070498	interleukin-1-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070499	exosporium assembly	biological_process	A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.
GO:0070501	poly-gamma-glutamate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.
GO:0070502	capsule poly-gamma-glutamate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.
GO:0070503	selenium-containing prosthetic group metabolic process	biological_process	The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.
GO:0070504	selenium-containing prosthetic group biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.
GO:0070505	pollen coat	cellular_component	A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.
GO:0070506	high-density lipoprotein particle receptor activity	molecular_function	Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.
GO:0070507	regulation of microtubule cytoskeleton organization	biological_process	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GO:0070508	cholesterol import	biological_process	The directed movement of cholesterol into a cell or organelle.
GO:0070509	calcium ion import	biological_process	The directed movement of calcium ions into a cell or organelle.
GO:0070512	positive regulation of histone H4-K20 methylation	biological_process	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
GO:0070513	death domain binding	molecular_function	Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
GO:0070514	SRF-myogenin-E12 complex	cellular_component	A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.
GO:0070515	alphaIIb-beta3 integrin-talin complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.
GO:0070516	CAK-ERCC2 complex	cellular_component	A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.
GO:0070517	DNA replication factor C core complex	cellular_component	A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.
GO:0070518	alpha4-beta1 integrin-CD53 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.
GO:0070519	alpha4-beta1 integrin-CD63 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.
GO:0070520	alpha4-beta1 integrin-CD81 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.
GO:0070521	alpha4-beta1 integrin-CD82 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.
GO:0070522	ERCC4-ERCC1 complex	cellular_component	A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.
GO:0070523	11-beta-hydroxysteroid dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.
GO:0070524	11-beta-hydroxysteroid dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.
GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	biological_process	The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
GO:0070527	platelet aggregation	biological_process	The adhesion of one platelet to one or more other platelets via adhesion molecules.
GO:0070528	protein kinase C signaling	biological_process	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
GO:0070529	L-tryptophan aminotransferase activity	molecular_function	Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.
GO:0070531	BRCA1-A complex	cellular_component	A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.
GO:0070532	BRCA1-B complex	cellular_component	A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.
GO:0070533	BRCA1-C complex	cellular_component	A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.
GO:0070534	protein K63-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
GO:0070535	histone H2A K63-linked ubiquitination	biological_process	A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.
GO:0070536	protein K63-linked deubiquitination	biological_process	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
GO:0070537	histone H2A K63-linked deubiquitination	biological_process	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.
GO:0070538	oleic acid binding	molecular_function	Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.
GO:0070539	linoleic acid binding	molecular_function	Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
GO:0070540	stearic acid binding	molecular_function	Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.
GO:0070541	response to platinum ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.
GO:0070542	response to fatty acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
GO:0070543	response to linoleic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.
GO:0070544	histone H3-K36 demethylation	biological_process	The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.
GO:0070545	PeBoW complex	cellular_component	A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.
GO:0070546	L-phenylalanine aminotransferase activity	molecular_function	Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.
GO:0070547	L-tyrosine aminotransferase activity	molecular_function	Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.
GO:0070548	L-glutamine aminotransferase activity	molecular_function	Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.
GO:0070549	siRNA-mediated gene silencing by inhibition of translation	biological_process	An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs.
GO:0070550	rDNA chromatin condensation	biological_process	The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.
GO:0070551	endoribonuclease activity, cleaving siRNA-paired mRNA	molecular_function	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.
GO:0070552	BRISC complex	cellular_component	A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.
GO:0070553	nicotinic acid receptor activity	molecular_function	Combining with nicotinic acid to initiate a change in cell activity.
GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex	cellular_component	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).
GO:0070555	response to interleukin-1	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
GO:0070556	TAF4B-containing transcription factor TFIID complex	cellular_component	A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.
GO:0070557	PCNA-p21 complex	cellular_component	A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.
GO:0070558	alphaM-beta2 integrin-CD63 complex	cellular_component	A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.
GO:0070559	lysosomal multienzyme complex	cellular_component	A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.
GO:0070560	protein secretion by platelet	biological_process	The regulated release of proteins by a platelet or group of platelets.
GO:0070561	vitamin D receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.
GO:0070562	regulation of vitamin D receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.
GO:0070563	negative regulation of vitamin D receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.
GO:0070564	positive regulation of vitamin D receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.
GO:0070565	telomere-telomerase complex	cellular_component	A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.
GO:0070566	adenylyltransferase activity	molecular_function	Catalysis of the transfer of an adenylyl group to an acceptor.
GO:0070567	cytidylyltransferase activity	molecular_function	Catalysis of the transfer of a cytidylyl group to an acceptor.
GO:0070568	guanylyltransferase activity	molecular_function	Catalysis of the transfer of a guanylyl group to an acceptor.
GO:0070569	uridylyltransferase activity	molecular_function	Catalysis of the transfer of an uridylyl group to an acceptor.
GO:0070570	regulation of neuron projection regeneration	biological_process	Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
GO:0070571	negative regulation of neuron projection regeneration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
GO:0070572	positive regulation of neuron projection regeneration	biological_process	Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
GO:0070573	metallodipeptidase activity	molecular_function	Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0070574	cadmium ion transmembrane transport	biological_process	A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0070575	peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation	biological_process	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.
GO:0070576	vitamin D 24-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of C-24 of any form of vitamin D.
GO:0070577	lysine-acetylated histone binding	molecular_function	Binding to a histone in which a lysine residue has been modified by acetylation.
GO:0070578	RISC-loading complex	cellular_component	A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.
GO:0070579	methylcytosine dioxygenase activity	molecular_function	Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.
GO:0070580	base J metabolic process	biological_process	The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.
GO:0070581	rolling circle DNA replication	biological_process	A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.
GO:0070582	theta DNA replication	biological_process	A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.
GO:0070583	spore membrane bending pathway	biological_process	The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.
GO:0070584	mitochondrion morphogenesis	biological_process	The process in which the anatomical structures of a mitochondrion are generated and organized.
GO:0070585	protein localization to mitochondrion	biological_process	A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
GO:0070586	cell-cell adhesion involved in gastrulation	biological_process	The attachment of one cell to another cell affecting gastrulation.
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	biological_process	Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.
GO:0070588	calcium ion transmembrane transport	biological_process	A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0070590	spore wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.
GO:0070591	ascospore wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.
GO:0070592	cell wall polysaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.
GO:0070593	dendrite self-avoidance	biological_process	The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
GO:0070594	juvenile hormone response element binding	molecular_function	Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.
GO:0070595	(1->3)-alpha-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
GO:0070596	(1->3)-alpha-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
GO:0070597	cell wall (1->3)-alpha-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
GO:0070598	cell wall (1->3)-alpha-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.
GO:0070599	fungal-type cell wall (1->3)-alpha-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
GO:0070600	fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
GO:0070601	centromeric sister chromatid cohesion	biological_process	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.
GO:0070602	regulation of centromeric sister chromatid cohesion	biological_process	Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.
GO:0070603	SWI/SNF superfamily-type complex	cellular_component	A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
GO:0070605	regulation of (1->3)-alpha-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
GO:0070606	regulation of (1->3)-alpha-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
GO:0070607	regulation of cell wall (1->3)-alpha-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
GO:0070608	regulation of cell wall (1->3)-alpha-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
GO:0070609	regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
GO:0070610	regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
GO:0070611	histone H3R2 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.
GO:0070612	histone H2AR3 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H2A.
GO:0070613	regulation of protein processing	biological_process	Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
GO:0070614	tungstate ion transport	biological_process	The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.
GO:0070616	regulation of thiamine diphosphate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
GO:0070617	negative regulation of thiamine diphosphate biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
GO:0070618	Grb2-Sos complex	cellular_component	A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070619	Shc-Grb2-Sos complex	cellular_component	A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070620	EGFR-Grb2-Sos complex	cellular_component	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070621	EGFR-Shc-Grb2-Sos complex	cellular_component	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
GO:0070622	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	cellular_component	A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.
GO:0070623	regulation of thiamine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
GO:0070624	negative regulation of thiamine biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
GO:0070625	zymogen granule exocytosis	biological_process	The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.
GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity	molecular_function	Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
GO:0070628	proteasome binding	molecular_function	Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
GO:0070629	(1->4)-alpha-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
GO:0070630	(1->4)-alpha-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
GO:0070631	spindle pole body localization	biological_process	Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
GO:0070633	transepithelial transport	biological_process	The directed movement of a substance from one side of an epithelium to the other.
GO:0070634	transepithelial ammonium transport	biological_process	The directed movement of ammonium ions from one side of an epithelium to the other.
GO:0070635	nicotinamide riboside hydrolase activity	molecular_function	Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
GO:0070636	nicotinic acid riboside hydrolase activity	molecular_function	Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
GO:0070637	pyridine nucleoside metabolic process	biological_process	The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
GO:0070638	pyridine nucleoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
GO:0070639	vitamin D2 metabolic process	biological_process	The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.
GO:0070640	vitamin D3 metabolic process	biological_process	The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
GO:0070641	vitamin D4 metabolic process	biological_process	The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.
GO:0070642	vitamin D5 metabolic process	biological_process	The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.
GO:0070643	vitamin D 25-hydroxylase activity	molecular_function	Catalysis of the hydroxylation of C-25 of any form of vitamin D.
GO:0070644	vitamin D response element binding	molecular_function	Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
GO:0070645	Ubisch body	cellular_component	A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.
GO:0070646	protein modification by small protein removal	biological_process	A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.
GO:0070647	protein modification by small protein conjugation or removal	biological_process	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
GO:0070648	formin-nucleated actin cable	cellular_component	An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.
GO:0070649	formin-nucleated actin cable assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
GO:0070650	actin filament bundle distribution	biological_process	Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.
GO:0070651	nonfunctional rRNA decay	biological_process	An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.
GO:0070652	HAUS complex	cellular_component	A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.
GO:0070653	high-density lipoprotein particle receptor binding	molecular_function	Binding to a high-density lipoprotein receptor.
GO:0070654	sensory epithelium regeneration	biological_process	The regrowth of a sensory epithelium following its loss or destruction.
GO:0070655	mechanosensory epithelium regeneration	biological_process	The regrowth of lost or destroyed mechanosensory epithelia.
GO:0070656	mechanoreceptor differentiation involved in mechanosensory epithelium regeneration	biological_process	Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.
GO:0070657	neuromast regeneration	biological_process	The regrowth of a neuromast following its loss or destruction.
GO:0070658	neuromast hair cell differentiation involved in neuromast regeneration	biological_process	Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.
GO:0070659	inner ear sensory epithelium regeneration	biological_process	The regrowth of lost or destroyed inner ear sensory epithelia.
GO:0070660	inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration	biological_process	Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.
GO:0070661	leukocyte proliferation	biological_process	The expansion of a leukocyte population by cell division.
GO:0070662	mast cell proliferation	biological_process	The expansion of a mast cell population by cell division.
GO:0070663	regulation of leukocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of leukocyte proliferation.
GO:0070664	negative regulation of leukocyte proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.
GO:0070665	positive regulation of leukocyte proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.
GO:0070666	regulation of mast cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mast cell proliferation.
GO:0070667	negative regulation of mast cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
GO:0070668	positive regulation of mast cell proliferation	biological_process	Any process that activates or increases the rate or extent of mast cell proliferation.
GO:0070669	response to interleukin-2	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
GO:0070670	response to interleukin-4	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
GO:0070671	response to interleukin-12	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
GO:0070672	response to interleukin-15	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
GO:0070673	response to interleukin-18	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
GO:0070674	hypoxanthine dehydrogenase activity	molecular_function	Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.
GO:0070675	hypoxanthine oxidase activity	molecular_function	Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.
GO:0070676	intralumenal vesicle formation	biological_process	The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
GO:0070677	rRNA (cytosine-2'-O-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.
GO:0070678	preprotein binding	molecular_function	Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.
GO:0070679	inositol 1,4,5 trisphosphate binding	molecular_function	Binding to inositol 1,4,5 trisphosphate.
GO:0070680	asparaginyl-tRNAAsn biosynthesis via transamidation	biological_process	A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	biological_process	A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.
GO:0070682	proteasome regulatory particle assembly	biological_process	The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.
GO:0070684	seminal clot liquefaction	biological_process	The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.
GO:0070685	macropinocytic cup	cellular_component	A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.
GO:0070686	macropinocytic cup membrane	cellular_component	The portion of the plasma membrane surrounding a macropinocytic cup.
GO:0070687	macropinocytic cup cytoskeleton	cellular_component	The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.
GO:0070689	L-threonine catabolic process to propionate	biological_process	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.
GO:0070690	L-threonine catabolic process to acetyl-CoA	biological_process	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.
GO:0070691	P-TEFb complex	cellular_component	A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.
GO:0070692	CTDK-1 complex	cellular_component	A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).
GO:0070693	P-TEFb-cap methyltransferase complex	cellular_component	A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.
GO:0070694	deoxyribonucleoside 5'-monophosphate N-glycosidase activity	molecular_function	Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.
GO:0070695	FHF complex	cellular_component	A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	molecular_function	Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.
GO:0070697	activin receptor binding	molecular_function	Binding to an activin receptor.
GO:0070698	type I activin receptor binding	molecular_function	Binding to a type I activin receptor.
GO:0070699	type II activin receptor binding	molecular_function	Binding to a type II activin receptor.
GO:0070700	BMP receptor binding	molecular_function	Binding to a BMP receptor.
GO:0070701	mucus layer	cellular_component	An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.
GO:0070702	inner mucus layer	cellular_component	The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.
GO:0070703	outer mucus layer	cellular_component	The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.
GO:0070704	sterol desaturase activity	molecular_function	Catalysis of the introduction of a double bond into a sterol molecule.
GO:0070705	RNA nucleotide insertion	biological_process	The modification of an RNA molecule by insertion of one or more nucleotides.
GO:0070706	RNA nucleotide deletion	biological_process	The modification of an RNA molecule by removal of a single nucleotide.
GO:0070707	RNA dinucleotide insertion	biological_process	The modification of an RNA molecule by insertion of a dinucleotide.
GO:0070708	RNA cytidine insertion	biological_process	The modification of an RNA molecule by insertion of a cytidine nucleotide.
GO:0070709	RNA guanosine insertion	biological_process	The modification of an RNA molecule by insertion of a guanosine nucleotide.
GO:0070710	RNA uridine deletion	biological_process	The modification of an RNA molecule by removal of a uridine nucleotide.
GO:0070711	RNA adenosine-uridine insertion	biological_process	The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.
GO:0070712	RNA cytidine-uridine insertion	biological_process	The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.
GO:0070713	RNA guanosine-cytidine insertion	biological_process	The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.
GO:0070714	RNA guanosine-uridine insertion	biological_process	The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.
GO:0070715	sodium-dependent organic cation transport	biological_process	The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0070716	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	biological_process	A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.
GO:0070717	poly-purine tract binding	molecular_function	Binding to a stretch of purines (adenine or guanine) in an RNA molecule.
GO:0070718	alphaPDGFR-SHP-2 complex	cellular_component	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.
GO:0070719	alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex	cellular_component	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.
GO:0070720	Grb2-SHP-2 complex	cellular_component	A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.
GO:0070721	ISGF3 complex	cellular_component	A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.
GO:0070722	Tle3-Aes complex	cellular_component	A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.
GO:0070723	response to cholesterol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
GO:0070724	BMP receptor complex	cellular_component	A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.
GO:0070725	Yb body	cellular_component	A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.
GO:0070726	cell wall assembly	biological_process	The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
GO:0070727	cellular macromolecule localization	biological_process	Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0070728	leucine binding	molecular_function	Binding to 2-amino-4-methylpentanoic acid.
GO:0070729	cyclic nucleotide transport	biological_process	The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.
GO:0070730	cAMP transport	biological_process	The directed movement of cyclic AMP (cAMP), into, out of or within a cell.
GO:0070731	cGMP transport	biological_process	The directed movement of cyclic GMP (cGMP), into, out of or within a cell.
GO:0070732	spindle envelope	cellular_component	An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.
GO:0070733	protein adenylyltransferase activity	molecular_function	Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to L-serine, L-threonine, and L-tyrosine residues in target proteins.
GO:0070734	histone H3-K27 methylation	biological_process	The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.
GO:0070735	protein-glycine ligase activity	molecular_function	Catalysis of the reaction: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H+ + phosphate.
GO:0070736	protein-glycine ligase activity, initiating	molecular_function	Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.
GO:0070737	protein-glycine ligase activity, elongating	molecular_function	Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.
GO:0070738	tubulin-glycine ligase activity	molecular_function	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.
GO:0070739	protein-glutamic acid ligase activity	molecular_function	Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.
GO:0070740	tubulin-glutamic acid ligase activity	molecular_function	Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.
GO:0070741	response to interleukin-6	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
GO:0070742	C2H2 zinc finger domain binding	molecular_function	Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
GO:0070743	interleukin-23 complex	cellular_component	A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.
GO:0070744	interleukin-27 complex	cellular_component	A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
GO:0070745	interleukin-35 complex	cellular_component	A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.
GO:0070746	interleukin-35 binding	molecular_function	Binding to interleukin-35.
GO:0070747	interleukin-35 receptor activity	molecular_function	Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0070748	interleukin-35 receptor binding	molecular_function	Binding to an interleukin-35 receptor.
GO:0070753	interleukin-35 production	biological_process	The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0070754	regulation of interleukin-35 production	biological_process	Any process that modulates the frequency, rate, or extent of interleukin-35 production.
GO:0070755	negative regulation of interleukin-35 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.
GO:0070756	positive regulation of interleukin-35 production	biological_process	Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.
GO:0070757	interleukin-35-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-35 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0070758	regulation of interleukin-35-mediated signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway.
GO:0070759	negative regulation of interleukin-35-mediated signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.
GO:0070760	positive regulation of interleukin-35-mediated signaling pathway	biological_process	Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.
GO:0070761	pre-snoRNP complex	cellular_component	A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
GO:0070762	nuclear pore transmembrane ring	cellular_component	A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
GO:0070763	Delta1 complex	cellular_component	A protein complex that consists of homodimer of the Notch ligand Delta1.
GO:0070764	gamma-secretase-Delta1 complex	cellular_component	A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.
GO:0070765	gamma-secretase complex	cellular_component	A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein.
GO:0070766	endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex	cellular_component	A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).
GO:0070767	BRCA1-Rad51 complex	cellular_component	A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.
GO:0070768	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex	cellular_component	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).
GO:0070769	alphaIIb-beta3 integrin-CIB complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.
GO:0070770	alphaIIb-beta3 integrin-CD47-FAK complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.
GO:0070771	alphaIIb-beta3 integrin-CD47-Src complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.
GO:0070772	PAS complex	cellular_component	A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.
GO:0070773	protein-N-terminal glutamine amidohydrolase activity	molecular_function	Catalysis of the reaction: N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.
GO:0070774	phytoceramidase activity	molecular_function	Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.
GO:0070775	H3 histone acetyltransferase complex	cellular_component	A multisubunit complex that catalyzes the acetylation of histone H3.
GO:0070776	MOZ/MORF histone acetyltransferase complex	cellular_component	A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
GO:0070777	D-aspartate transport	biological_process	The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0070778	L-aspartate transmembrane transport	biological_process	The directed movement of L-aspartate across a membrane.
GO:0070779	D-aspartate import across plasma membrane	biological_process	The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.
GO:0070780	dihydrosphingosine-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.
GO:0070781	response to biotin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.
GO:0070782	phosphatidylserine exposure on apoptotic cell surface	biological_process	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.
GO:0070783	growth of unicellular organism as a thread of attached cells	biological_process	A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.
GO:0070784	regulation of growth of unicellular organism as a thread of attached cells	biological_process	Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
GO:0070785	negative regulation of growth of unicellular organism as a thread of attached cells	biological_process	Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
GO:0070786	positive regulation of growth of unicellular organism as a thread of attached cells	biological_process	Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
GO:0070787	conidiophore development	biological_process	The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
GO:0070788	conidiophore stalk development	biological_process	The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
GO:0070789	metula development	biological_process	The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
GO:0070790	phialide development	biological_process	The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.
GO:0070791	cleistothecium development	biological_process	The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
GO:0070792	Hulle cell development	biological_process	The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
GO:0070793	regulation of conidiophore development	biological_process	Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
GO:0070794	negative regulation of conidiophore development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
GO:0070795	positive regulation of conidiophore development	biological_process	Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
GO:0070796	regulation of cleistothecium development	biological_process	Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
GO:0070797	negative regulation of cleistothecium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
GO:0070798	positive regulation of cleistothecium development	biological_process	Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
GO:0070799	regulation of conidiophore stalk development	biological_process	Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
GO:0070800	negative regulation of conidiophore stalk development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
GO:0070801	positive regulation of conidiophore stalk development	biological_process	Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
GO:0070802	regulation of metula development	biological_process	Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
GO:0070803	negative regulation of metula development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
GO:0070804	positive regulation of metula development	biological_process	Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
GO:0070805	regulation of phialide development	biological_process	Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
GO:0070806	negative regulation of phialide development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
GO:0070807	positive regulation of phialide development	biological_process	Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
GO:0070808	regulation of Hulle cell development	biological_process	Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
GO:0070809	negative regulation of Hulle cell development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
GO:0070810	positive regulation of Hulle cell development	biological_process	Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
GO:0070811	glycerol-2-phosphate transmembrane transport	biological_process	The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.
GO:0070813	hydrogen sulfide metabolic process	biological_process	The chemical reactions and pathways involving hydrogen sulfide, H2S.
GO:0070814	hydrogen sulfide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
GO:0070815	peptidyl-lysine 5-dioxygenase activity	molecular_function	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
GO:0070817	P-TEFb-cap methyltransferase complex localization	biological_process	Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.
GO:0070818	protoporphyrinogen oxidase activity	molecular_function	Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.
GO:0070819	menaquinone-dependent protoporphyrinogen oxidase activity	molecular_function	Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.
GO:0070820	tertiary granule	cellular_component	A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.
GO:0070821	tertiary granule membrane	cellular_component	The lipid bilayer surrounding a tertiary granule.
GO:0070822	Sin3-type complex	cellular_component	Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.
GO:0070823	HDA1 complex	cellular_component	A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.
GO:0070824	SHREC complex	cellular_component	A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.
GO:0070825	chrorion micropyle	cellular_component	A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.
GO:0070826	paraferritin complex	cellular_component	A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.
GO:0070828	heterochromatin organization	biological_process	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.
GO:0070830	bicellular tight junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
GO:0070831	basement membrane assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.
GO:0070832	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline	biological_process	The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
GO:0070833	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine	biological_process	The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
GO:0070834	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine	biological_process	The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
GO:0070835	chromium ion transmembrane transporter activity	molecular_function	Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.
GO:0070836	caveola assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.
GO:0070837	dehydroascorbic acid transport	biological_process	The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
GO:0070840	dynein complex binding	molecular_function	Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
GO:0070841	inclusion body assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an inclusion body.
GO:0070842	aggresome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.
GO:0070843	misfolded protein transport	biological_process	The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
GO:0070844	polyubiquitinated protein transport	biological_process	The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
GO:0070845	polyubiquitinated misfolded protein transport	biological_process	The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
GO:0070846	Hsp90 deacetylation	biological_process	The modification of an Hsp90 protein by removal of acetyl groups.
GO:0070847	core mediator complex	cellular_component	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
GO:0070848	response to growth factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
GO:0070849	response to epidermal growth factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
GO:0070850	TACC/TOG complex	cellular_component	A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.
GO:0070851	growth factor receptor binding	molecular_function	Binding to a growth factor receptor.
GO:0070852	cell body fiber	cellular_component	A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.
GO:0070853	myosin VI binding	molecular_function	Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
GO:0070854	myosin VI heavy chain binding	molecular_function	Binding to a heavy chain of a myosin VI complex.
GO:0070855	myosin VI head/neck binding	molecular_function	Binding to the head/neck region of a myosin VI heavy chain.
GO:0070856	myosin VI light chain binding	molecular_function	Binding to a light chain of a myosin VI complex.
GO:0070857	regulation of bile acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
GO:0070858	negative regulation of bile acid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
GO:0070859	positive regulation of bile acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
GO:0070860	RNA polymerase I core factor complex	cellular_component	A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.
GO:0070861	regulation of protein exit from endoplasmic reticulum	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
GO:0070862	negative regulation of protein exit from endoplasmic reticulum	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	biological_process	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
GO:0070864	sperm individualization complex	cellular_component	A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.
GO:0070865	investment cone	cellular_component	A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.
GO:0070866	sterol-dependent protein binding	molecular_function	Binding to a protein or protein complex in the presence of sterols.
GO:0070867	mating projection tip membrane	cellular_component	The portion of the plasma membrane surrounding a mating projection tip.
GO:0070871	cell wall organization involved in conjugation with cellular fusion	biological_process	A process of cell wall organization that contributes to conjugation with cellular fusion.
GO:0070873	regulation of glycogen metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
GO:0070874	negative regulation of glycogen metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
GO:0070875	positive regulation of glycogen metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
GO:0070876	SOSS complex	cellular_component	A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.
GO:0070877	microprocessor complex	cellular_component	A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.
GO:0070878	primary miRNA binding	molecular_function	Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.
GO:0070879	fungal-type cell wall beta-glucan metabolic process	biological_process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
GO:0070880	fungal-type cell wall beta-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
GO:0070881	regulation of proline transport	biological_process	Any process that modulates the frequency, rate or extent of proline transport.
GO:0070883	pre-miRNA binding	molecular_function	Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
GO:0070884	regulation of calcineurin-NFAT signaling cascade	biological_process	Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	biological_process	Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
GO:0070887	cellular response to chemical stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0070888	E-box binding	molecular_function	Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
GO:0070889	platelet alpha granule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.
GO:0070891	lipoteichoic acid binding	molecular_function	Binding to lipoteichoic acid.
GO:0070892	lipoteichoic acid immune receptor activity	molecular_function	Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.
GO:0070897	transcription preinitiation complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.
GO:0070898	RNA polymerase III preinitiation complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.
GO:0070899	mitochondrial tRNA wobble uridine modification	biological_process	The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.
GO:0070900	mitochondrial tRNA modification	biological_process	The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.
GO:0070901	mitochondrial tRNA methylation	biological_process	The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
GO:0070902	mitochondrial tRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.
GO:0070903	mitochondrial tRNA thio-modification	biological_process	The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.
GO:0070905	serine binding	molecular_function	Binding to 2-amino-3-hydroxypropanoic acid.
GO:0070906	aspartate:alanine antiporter activity	molecular_function	Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).
GO:0070907	histidine:histamine antiporter activity	molecular_function	Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out).
GO:0070908	tyrosine:tyramine antiporter activity	molecular_function	Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).
GO:0070909	glutamate:gamma-aminobutyric acid antiporter activity	molecular_function	Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).
GO:0070910	cell wall macromolecule catabolic process involved in cell wall disassembly	biological_process	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.
GO:0070911	global genome nucleotide-excision repair	biological_process	The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
GO:0070912	Ddb1-Ckn1 complex	cellular_component	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
GO:0070913	Ddb1-Wdr21 complex	cellular_component	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
GO:0070914	UV-damage excision repair	biological_process	A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
GO:0070915	lysophosphatidic acid receptor activity	molecular_function	Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.
GO:0070916	inositol phosphoceramide synthase complex	cellular_component	A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).
GO:0070917	inositol phosphoceramide synthase regulator activity	molecular_function	Binds to and modulates the activity of inositol phosphoceramide synthase.
GO:0070918	regulatory ncRNA processing	biological_process	A process leading to the generation of a functional regulatory non-coding RNA.
GO:0070920	regulation of regulatory ncRNA processing	biological_process	Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing.
GO:0070921	regulation of siRNA processing	biological_process	Any process that modulates the frequency, rate or extent of siRNA processing.
GO:0070922	RISC complex assembly	biological_process	The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA.
GO:0070925	organelle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0070926	regulation of ATP:ADP antiporter activity	biological_process	Any process that modulates the activity of an ATP:ADP antiporter.
GO:0070927	negative regulation of ATP:ADP antiporter activity	biological_process	Any process that stops or reduces the activity of an ATP:ADP antiporter.
GO:0070929	trans-translation	biological_process	A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.
GO:0070930	trans-translation-dependent protein tagging	biological_process	A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.
GO:0070931	Golgi-associated vesicle lumen	cellular_component	The volume enclosed by the membrane of a Golgi-associated vesicle.
GO:0070932	histone H3 deacetylation	biological_process	The modification of histone H3 by the removal of one or more acetyl groups.
GO:0070933	histone H4 deacetylation	biological_process	The modification of histone H4 by the removal of one or more acetyl groups.
GO:0070934	CRD-mediated mRNA stabilization	biological_process	An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).
GO:0070935	3'-UTR-mediated mRNA stabilization	biological_process	An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
GO:0070936	protein K48-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
GO:0070937	CRD-mediated mRNA stability complex	cellular_component	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
GO:0070938	contractile ring	cellular_component	A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.
GO:0070939	Dsl1/NZR complex	cellular_component	A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.
GO:0070941	eisosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.
GO:0070942	neutrophil mediated cytotoxicity	biological_process	The directed killing of a target cell by a neutrophil.
GO:0070943	neutrophil-mediated killing of symbiont cell	biological_process	The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0070944	neutrophil-mediated killing of bacterium	biological_process	The directed killing of a bacterium by a neutrophil.
GO:0070945	neutrophil-mediated killing of gram-negative bacterium	biological_process	The directed killing of a gram-negative bacterium by a neutrophil.
GO:0070946	neutrophil-mediated killing of gram-positive bacterium	biological_process	The directed killing of a gram-positive bacterium by a neutrophil.
GO:0070947	neutrophil-mediated killing of fungus	biological_process	The directed killing of a fungal cell by a neutrophil.
GO:0070948	regulation of neutrophil mediated cytotoxicity	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.
GO:0070949	regulation of neutrophil mediated killing of symbiont cell	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.
GO:0070950	regulation of neutrophil mediated killing of bacterium	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.
GO:0070951	regulation of neutrophil mediated killing of gram-negative bacterium	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.
GO:0070952	regulation of neutrophil mediated killing of gram-positive bacterium	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.
GO:0070953	regulation of neutrophil mediated killing of fungus	biological_process	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.
GO:0070954	negative regulation of neutrophil mediated cytotoxicity	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.
GO:0070955	negative regulation of neutrophil mediated killing of symbiont cell	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.
GO:0070956	negative regulation of neutrophil mediated killing of bacterium	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.
GO:0070957	negative regulation of neutrophil mediated killing of gram-negative bacterium	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
GO:0070958	negative regulation of neutrophil mediated killing of gram-positive bacterium	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
GO:0070959	negative regulation of neutrophil mediated killing of fungus	biological_process	Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
GO:0070960	positive regulation of neutrophil mediated cytotoxicity	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.
GO:0070961	positive regulation of neutrophil mediated killing of symbiont cell	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.
GO:0070962	positive regulation of neutrophil mediated killing of bacterium	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
GO:0070964	positive regulation of neutrophil mediated killing of gram-positive bacterium	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
GO:0070965	positive regulation of neutrophil mediated killing of fungus	biological_process	Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay	biological_process	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
GO:0070967	coenzyme F420 binding	molecular_function	Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0070968	pyrroloquinoline quinone binding	molecular_function	Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.
GO:0070971	endoplasmic reticulum exit site	cellular_component	An endoplasmic reticulum part at which COPII-coated vesicles are produced.
GO:0070972	protein localization to endoplasmic reticulum	biological_process	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
GO:0070973	protein localization to endoplasmic reticulum exit site	biological_process	A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.
GO:0070974	POU domain binding	molecular_function	Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.
GO:0070975	FHA domain binding	molecular_function	Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.
GO:0070976	TIR domain binding	molecular_function	Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.
GO:0070977	bone maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.
GO:0070978	voltage-gated calcium channel complex assembly	biological_process	Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.
GO:0070979	protein K11-linked ubiquitination	biological_process	A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
GO:0070980	biphenyl catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
GO:0070981	L-asparagine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
GO:0070982	L-asparagine metabolic process	biological_process	The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
GO:0070983	dendrite guidance	biological_process	The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.
GO:0070984	SET domain binding	molecular_function	Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.
GO:0070985	transcription factor TFIIK complex	cellular_component	A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.
GO:0070986	left/right axis specification	biological_process	The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).
GO:0070987	error-free translesion synthesis	biological_process	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.
GO:0070988	demethylation	biological_process	The process of removing one or more methyl groups from a molecule.
GO:0070989	oxidative demethylation	biological_process	The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.
GO:0070990	snRNP binding	molecular_function	Binding to a small nuclear ribonucleoprotein particle.
GO:0070991	medium-chain-acyl-CoA dehydrogenase activity	molecular_function	Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.
GO:0070992	translation initiation complex	cellular_component	A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
GO:0070993	translation preinitiation complex	cellular_component	A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.
GO:0070994	detection of oxidative stress	biological_process	The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.
GO:0070995	NADPH oxidation	biological_process	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
GO:0070996	type 1 melanocortin receptor binding	molecular_function	Binding to a type 1 melanocortin receptor.
GO:0070998	sensory perception of gravity	biological_process	The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0070999	detection of mechanical stimulus involved in sensory perception of gravity	biological_process	The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.
GO:0071000	response to magnetism	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
GO:0071001	U4/U6 snRNP	cellular_component	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.
GO:0071002	U4atac/U6atac snRNP	cellular_component	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.
GO:0071003	penta-snRNP complex	cellular_component	A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.
GO:0071004	U2-type prespliceosome	cellular_component	A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
GO:0071005	U2-type precatalytic spliceosome	cellular_component	A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.
GO:0071006	U2-type catalytic step 1 spliceosome	cellular_component	A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
GO:0071007	U2-type catalytic step 2 spliceosome	cellular_component	A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.
GO:0071008	U2-type post-mRNA release spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.
GO:0071009	U4atac/U6atac x U5 tri-snRNP complex	cellular_component	A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.
GO:0071010	prespliceosome	cellular_component	A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.
GO:0071011	precatalytic spliceosome	cellular_component	A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
GO:0071012	catalytic step 1 spliceosome	cellular_component	A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
GO:0071013	catalytic step 2 spliceosome	cellular_component	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
GO:0071014	post-mRNA release spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, either U2 or U12, U5, and either U6 or U6atac.
GO:0071015	U12-type prespliceosome	cellular_component	A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
GO:0071016	U12-type precatalytic spliceosome	cellular_component	A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.
GO:0071017	U12-type catalytic step 1 spliceosome	cellular_component	A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.
GO:0071018	U12-type catalytic step 2 spliceosome	cellular_component	A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.
GO:0071019	U12-type post-mRNA release spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.
GO:0071020	post-spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.
GO:0071021	U2-type post-spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.
GO:0071022	U12-type post-spliceosomal complex	cellular_component	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.
GO:0071023	trans spliceosomal complex	cellular_component	A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.
GO:0071024	SL snRNP	cellular_component	A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.
GO:0071025	RNA surveillance	biological_process	A process that identifies and degrades defective or aberrant RNAs.
GO:0071026	cytoplasmic RNA surveillance	biological_process	The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.
GO:0071027	nuclear RNA surveillance	biological_process	A process that identifies and degrades defective or aberrant RNAs within the nucleus.
GO:0071028	nuclear mRNA surveillance	biological_process	A process that identifies and degrades defective or aberrant mRNAs within the nucleus.
GO:0071029	nuclear ncRNA surveillance	biological_process	The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.
GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing	biological_process	The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.
GO:0071031	nuclear mRNA surveillance of mRNA 3'-end processing	biological_process	The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.
GO:0071032	nuclear mRNA surveillance of mRNP export	biological_process	The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.
GO:0071034	CUT catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.
GO:0071036	nuclear polyadenylation-dependent snoRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.
GO:0071037	nuclear polyadenylation-dependent snRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.
GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.
GO:0071039	nuclear polyadenylation-dependent CUT catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.
GO:0071040	nuclear polyadenylation-dependent antisense transcript catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.
GO:0071041	antisense RNA transcript catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
GO:0071043	CUT metabolic process	biological_process	The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.
GO:0071044	histone mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).
GO:0071045	nuclear histone mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.
GO:0071046	nuclear polyadenylation-dependent ncRNA catabolic process	biological_process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
GO:0071047	polyadenylation-dependent mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
GO:0071051	polyadenylation-dependent snoRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.
GO:0071052	alpha9-beta1 integrin-ADAM1 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.
GO:0071053	alpha9-beta1 integrin-ADAM2 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.
GO:0071054	alpha9-beta1 integrin-ADAM3 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.
GO:0071055	alpha9-beta1 integrin-ADAM9 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.
GO:0071056	alpha9-beta1 integrin-ADAM15 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.
GO:0071057	alphav-beta3 integrin-ADAM15 complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.
GO:0071058	alpha3-beta1 integrin-CD151 complex	cellular_component	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.
GO:0071059	alpha6-beta1 integrin-CD151 complex	cellular_component	A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.
GO:0071060	alpha7-beta1 integrin-CD151 complex	cellular_component	A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.
GO:0071061	alpha6-beta4 integrin-CD151 complex	cellular_component	A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.
GO:0071062	alphav-beta3 integrin-vitronectin complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.
GO:0071063	sensory perception of wind	biological_process	The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.
GO:0071064	alphaE-beta7 integrin-E-cadherin complex	cellular_component	A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.
GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.
GO:0071066	detection of mechanical stimulus involved in sensory perception of wind	biological_process	The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.
GO:0071067	alphav-beta3 integrin-ADAM23 complex	cellular_component	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.
GO:0071068	alpha9-beta1 integrin-ADAM12 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.
GO:0071069	alpha4-beta1 integrin-thrombospondin-1 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.
GO:0071070	alpha4-beta1 integrin-thrombospondin-2 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.
GO:0071071	regulation of phospholipid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
GO:0071072	negative regulation of phospholipid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
GO:0071073	positive regulation of phospholipid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
GO:0071074	eukaryotic initiation factor eIF2 binding	molecular_function	Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.
GO:0071075	CUGBP1-eIF2 complex	cellular_component	A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.
GO:0071076	RNA 3' uridylation	biological_process	The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.
GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity	molecular_function	Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.
GO:0071078	fibronectin-tissue transglutaminase complex	cellular_component	A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.
GO:0071079	alpha2-beta1 integrin-chondroadherin complex	cellular_component	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.
GO:0071080	alpha3-beta1 integrin-basigin complex	cellular_component	A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.
GO:0071081	alpha3-beta1 integrin-CD63 complex	cellular_component	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.
GO:0071082	alpha9-beta1 integrin-tenascin complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.
GO:0071083	alphaV-beta3 integrin-CD47-FCER2 complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).
GO:0071084	alpha2-beta1 integrin-CD47 complex	cellular_component	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.
GO:0071085	alphaIIb-beta3 integrin-CD9 complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.
GO:0071086	alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.
GO:0071087	alpha11-beta1 integrin-collagen type I complex	cellular_component	A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.
GO:0071088	alpha5-beta1 integrin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.
GO:0071089	alphaV-beta3 integrin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.
GO:0071090	alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.
GO:0071091	alpha1-beta1 integrin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.
GO:0071092	alpha3-beta1 integrin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.
GO:0071093	alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.
GO:0071094	alpha6-beta4 integrin-CD9 complex	cellular_component	A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.
GO:0071095	alpha3-beta1 integrin-thrombospondin complex	cellular_component	A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.
GO:0071096	alphaV-beta3 integrin-gelsolin complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.
GO:0071097	alphaV-beta3 integrin-paxillin-Pyk2 complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.
GO:0071098	alpha6-beta4 integrin-Fyn complex	cellular_component	A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.
GO:0071099	alphaV-beta6 integrin-TGFbeta-3 complex	cellular_component	A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).
GO:0071100	alphaV-beta8 integrin-MMP14-TGFbeta-1 complex	cellular_component	A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).
GO:0071101	alpha4-beta1 integrin-JAM2 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.
GO:0071102	alpha4-beta1 integrin-paxillin complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.
GO:0071103	DNA conformation change	biological_process	A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.
GO:0071104	response to interleukin-9	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.
GO:0071105	response to interleukin-11	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.
GO:0071106	adenosine 3',5'-bisphosphate transmembrane transport	biological_process	The process in which adenosine 3',5'-bisphosphate is transported across a membrane.
GO:0071107	response to parathyroid hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
GO:0071108	protein K48-linked deubiquitination	biological_process	A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
GO:0071109	superior temporal gyrus development	biological_process	The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.
GO:0071111	cyclic-guanylate-specific phosphodiesterase activity	molecular_function	Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.
GO:0071112	alpha4-beta4 integrin-EMILIN-1 complex	cellular_component	A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).
GO:0071113	alphaIIb-beta3 integrin-ICAM-4 complex	cellular_component	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.
GO:0071114	alphaV-beta3 integrin-tumstatin complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.
GO:0071115	alpha5-beta1 integrin-endostatin complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.
GO:0071116	alpha6-beta1 integrin-CYR61 complex	cellular_component	A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.
GO:0071117	alpha5-beta1 integrin-fibronectin-NOV complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.
GO:0071118	alphaV-beta3 integrin-NOV complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.
GO:0071119	alpha7-beta1 integrin-nicotinamide riboside kinase complex	cellular_component	A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).
GO:0071120	alpha4-beta1 integrin-CD47 complex	cellular_component	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.
GO:0071121	alpha9-beta1 integrin-VEGF-D complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.
GO:0071122	alpha9-beta1 integrin-VEGF-A complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.
GO:0071123	alpha9-beta1 integrin-VEGF-C complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.
GO:0071124	alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex	cellular_component	A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.
GO:0071125	alphaV-beta3 integrin-EGFR complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.
GO:0071126	alphaV-beta6 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.
GO:0071127	alpha9-beta1 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.
GO:0071128	alpha5-beta1 integrin-osteopontin complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.
GO:0071129	alphaV-beta3 integrin-LPP3 complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.
GO:0071130	alpha5-beta1 integrin-LPP3 complex	cellular_component	A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.
GO:0071131	alphaV-beta3 integrin-laminin alpha-4 complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.
GO:0071132	alphaX-beta2 integrin-ICAM-4 complex	cellular_component	A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.
GO:0071133	alpha9-beta1 integrin-ADAM8 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.
GO:0071134	alpha9-beta1 integrin-thrombospondin-1 complex	cellular_component	A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.
GO:0071135	alpha7-beta1 integrin-focal adhesion kinase complex	cellular_component	A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.
GO:0071136	alpha7-beta1 integrin-laminin alpha-2 complex	cellular_component	A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.
GO:0071137	alphaV-beta3 integrin-CD98 complex	cellular_component	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.
GO:0071138	alpha5-beta5-fibronectin-SFRP2 complex	cellular_component	A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.
GO:0071139	resolution of recombination intermediates	biological_process	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.
GO:0071140	resolution of mitotic recombination intermediates	biological_process	The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.
GO:0071141	SMAD protein complex	cellular_component	A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.
GO:0071142	homomeric SMAD protein complex	cellular_component	A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.
GO:0071144	heteromeric SMAD protein complex	cellular_component	A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.
GO:0071152	G-protein alpha(q)-synembrin complex	cellular_component	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.
GO:0071153	G-protein alpha(o)-synembrin complex	cellular_component	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.
GO:0071154	G-protein alpha(i)1-synembrin complex	cellular_component	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.
GO:0071155	G-protein alpha(13)-synembrin complex	cellular_component	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.
GO:0071159	NF-kappaB complex	cellular_component	A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.
GO:0071160	cyanophycin synthetase activity (L-aspartate-adding)	molecular_function	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.
GO:0071161	cyanophycin synthetase activity (L-arginine-adding)	molecular_function	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.
GO:0071162	CMG complex	cellular_component	A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.
GO:0071163	DNA replication preinitiation complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.
GO:0071164	RNA trimethylguanosine synthase activity	molecular_function	Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.
GO:0071165	GINS complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.
GO:0071166	ribonucleoprotein complex localization	biological_process	Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.
GO:0071168	protein localization to chromatin	biological_process	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
GO:0071169	establishment of protein localization to chromatin	biological_process	The directed movement of a protein to a part of a chromosome that is organized into chromatin.
GO:0071170	site-specific DNA replication termination	biological_process	A DNA replication termination process that takes place at a specific termination site.
GO:0071171	site-specific DNA replication termination at RTS1 barrier	biological_process	A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.
GO:0071172	dihydromonapterin reductase activity	molecular_function	Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.
GO:0071173	spindle assembly checkpoint signaling	biological_process	A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.
GO:0071174	mitotic spindle checkpoint signaling	biological_process	A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.
GO:0071175	MAML2-RBP-Jkappa-ICN1 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071176	MAML2-RBP-Jkappa-ICN2 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071177	MAML2-RBP-Jkappa-ICN3 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071178	MAML2-RBP-Jkappa-ICN4 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071179	MAML3-RBP-Jkappa-ICN1 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071180	MAML3-RBP-Jkappa-ICN2 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071181	MAML3-RBP-Jkappa-ICN3 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071182	MAML3-RBP-Jkappa-ICN4 complex	cellular_component	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
GO:0071183	protocadherin-alpha-protocadherin-gamma complex	cellular_component	A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071184	protocadherin-alpha-v4-protocadherin-gamma-a1 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071185	protocadherin-alpha-v4-protocadherin-gamma-a3 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071186	protocadherin-alpha-v4-protocadherin-gamma-b2 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071187	protocadherin-alpha-v4-protocadherin-gamma-b4 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071188	protocadherin-alpha-v7-protocadherin-gamma-a1 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071189	protocadherin-alpha-v7-protocadherin-gamma-a3 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071190	protocadherin-alpha-v7-protocadherin-gamma-b2 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071191	protocadherin-alpha-v7-protocadherin-gamma-b4 complex	cellular_component	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.
GO:0071192	Kv4.2-KChIP1 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.
GO:0071193	Kv4.2-KChIP2 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.
GO:0071194	Kv4.2-KChIP3 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.
GO:0071195	Kv4.2-KChIP4 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.
GO:0071196	Kv4.3-KChIP1 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.
GO:0071197	Kv4.2-Kv4.3 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.
GO:0071198	Kv4.1-DPP6 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.
GO:0071199	Kv4.1-DPP10 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.
GO:0071200	Kv4.2-DPP6 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.
GO:0071201	Kv4.3-DPP6 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.
GO:0071202	Kv4.3-DPP10 channel complex	cellular_component	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.
GO:0071203	WASH complex	cellular_component	A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.
GO:0071204	histone pre-mRNA 3'end processing complex	cellular_component	A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.
GO:0071205	protein localization to juxtaparanode region of axon	biological_process	Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.
GO:0071206	establishment of protein localization to juxtaparanode region of axon	biological_process	The directed movement of a protein to the juxtaparanode region of an axon.
GO:0071207	histone pre-mRNA stem-loop binding	molecular_function	Binding to a conserved stem-loop structure found in histone pre-mRNAs.
GO:0071208	histone pre-mRNA DCP binding	molecular_function	Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.
GO:0071209	U7 snRNA binding	molecular_function	Binding to a U7 small nuclear RNA (U7 snRNA).
GO:0071210	protein insertion into membrane raft	biological_process	The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
GO:0071211	protein targeting to vacuole involved in autophagy	biological_process	The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.
GO:0071212	subsynaptic reticulum	cellular_component	An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
GO:0071213	cellular response to 1-aminocyclopropane-1-carboxylic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.
GO:0071214	cellular response to abiotic stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
GO:0071215	cellular response to abscisic acid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
GO:0071216	cellular response to biotic stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0071217	cellular response to external biotic stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
GO:0071218	cellular response to misfolded protein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
GO:0071219	cellular response to molecule of bacterial origin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
GO:0071220	cellular response to bacterial lipoprotein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.
GO:0071221	cellular response to bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
GO:0071222	cellular response to lipopolysaccharide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
GO:0071223	cellular response to lipoteichoic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
GO:0071224	cellular response to peptidoglycan	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
GO:0071225	cellular response to muramyl dipeptide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
GO:0071226	cellular response to molecule of fungal origin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
GO:0071227	cellular response to molecule of oomycetes origin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.
GO:0071228	cellular response to tumor cell	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
GO:0071229	cellular response to acid chemical	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GO:0071230	cellular response to amino acid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
GO:0071231	cellular response to folic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
GO:0071232	cellular response to histidine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.
GO:0071233	cellular response to leucine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
GO:0071234	cellular response to phenylalanine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.
GO:0071235	cellular response to proline	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.
GO:0071236	cellular response to antibiotic	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
GO:0071237	cellular response to bacteriocin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
GO:0071238	cellular response to brefeldin A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.
GO:0071239	cellular response to streptomycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
GO:0071240	cellular response to food	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
GO:0071241	cellular response to inorganic substance	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
GO:0071242	cellular response to ammonium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.
GO:0071243	cellular response to arsenic-containing substance	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
GO:0071244	cellular response to carbon dioxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
GO:0071245	cellular response to carbon monoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
GO:0071246	cellular response to chlorate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.
GO:0071247	cellular response to chromate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
GO:0071248	cellular response to metal ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
GO:0071249	cellular response to nitrate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
GO:0071250	cellular response to nitrite	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.
GO:0071251	cellular response to silicon dioxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.
GO:0071252	cellular response to sulfur dioxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.
GO:0071253	connexin binding	molecular_function	Binding to a connexin, any of a group of related proteins that assemble to form gap junctions.
GO:0071254	cytoplasmic U snRNP body	cellular_component	A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.
GO:0071255	Cvt vesicle assembly	biological_process	A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).
GO:0071256	translocon complex	cellular_component	A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.
GO:0071257	cellular response to electrical stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
GO:0071258	cellular response to gravity	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.
GO:0071259	cellular response to magnetism	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
GO:0071260	cellular response to mechanical stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
GO:0071261	Ssh1 translocon complex	cellular_component	A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.
GO:0071262	regulation of translational initiation in response to starvation	biological_process	Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
GO:0071263	negative regulation of translational initiation in response to starvation	biological_process	Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.
GO:0071264	positive regulation of translational initiation in response to starvation	biological_process	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
GO:0071265	L-methionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.
GO:0071266	'de novo' L-methionine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.
GO:0071267	L-methionine salvage	biological_process	Any process that generates L-methionine from derivatives of it, without de novo synthesis.
GO:0071268	homocysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.
GO:0071269	L-homocysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.
GO:0071270	1-butanol metabolic process	biological_process	The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.
GO:0071271	1-butanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.
GO:0071272	morphine metabolic process	biological_process	The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
GO:0071273	morphine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
GO:0071274	isoquinoline alkaloid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
GO:0071275	cellular response to aluminum ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.
GO:0071276	cellular response to cadmium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
GO:0071277	cellular response to calcium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
GO:0071278	cellular response to cesium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.
GO:0071279	cellular response to cobalt ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
GO:0071280	cellular response to copper ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
GO:0071281	cellular response to iron ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
GO:0071282	cellular response to iron(II) ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
GO:0071283	cellular response to iron(III) ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.
GO:0071284	cellular response to lead ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
GO:0071285	cellular response to lithium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
GO:0071286	cellular response to magnesium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
GO:0071287	cellular response to manganese ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
GO:0071288	cellular response to mercury ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
GO:0071289	cellular response to nickel ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.
GO:0071290	cellular response to platinum ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.
GO:0071291	cellular response to selenium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.
GO:0071292	cellular response to silver ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
GO:0071293	cellular response to tellurium ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.
GO:0071294	cellular response to zinc ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
GO:0071295	cellular response to vitamin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
GO:0071296	cellular response to biotin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.
GO:0071297	cellular response to cobalamin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.
GO:0071298	cellular response to L-ascorbic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
GO:0071299	cellular response to vitamin A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
GO:0071300	cellular response to retinoic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
GO:0071301	cellular response to vitamin B1	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.
GO:0071302	cellular response to vitamin B2	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
GO:0071303	cellular response to vitamin B3	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.
GO:0071304	cellular response to vitamin B6	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
GO:0071305	cellular response to vitamin D	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
GO:0071306	cellular response to vitamin E	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
GO:0071307	cellular response to vitamin K	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
GO:0071308	cellular response to menaquinone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.
GO:0071309	cellular response to phylloquinone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.
GO:0071310	cellular response to organic substance	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GO:0071311	cellular response to acetate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.
GO:0071312	cellular response to alkaloid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
GO:0071313	cellular response to caffeine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
GO:0071314	cellular response to cocaine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
GO:0071315	cellular response to morphine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
GO:0071316	cellular response to nicotine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
GO:0071317	cellular response to isoquinoline alkaloid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
GO:0071318	cellular response to ATP	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
GO:0071319	cellular response to benzoic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.
GO:0071320	cellular response to cAMP	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
GO:0071321	cellular response to cGMP	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.
GO:0071322	cellular response to carbohydrate stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
GO:0071323	cellular response to chitin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
GO:0071324	cellular response to disaccharide stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.
GO:0071325	cellular response to mannitol stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.
GO:0071326	cellular response to monosaccharide stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
GO:0071327	cellular response to trehalose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.
GO:0071328	cellular response to maltose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.
GO:0071329	cellular response to sucrose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
GO:0071330	cellular response to trehalose-6-phosphate stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.
GO:0071331	cellular response to hexose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.
GO:0071332	cellular response to fructose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
GO:0071333	cellular response to glucose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
GO:0071334	cellular response to rhamnose stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.
GO:0071335	hair follicle cell proliferation	biological_process	The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.
GO:0071336	regulation of hair follicle cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.
GO:0071337	negative regulation of hair follicle cell proliferation	biological_process	Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.
GO:0071338	positive regulation of hair follicle cell proliferation	biological_process	Any process that activates or increases the rate or extent of hair follicle cell proliferation.
GO:0071339	MLL1 complex	cellular_component	A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.
GO:0071340	skeletal muscle acetylcholine-gated channel clustering	biological_process	The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.
GO:0071341	medial cortical node	cellular_component	A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.
GO:0071344	diphosphate metabolic process	biological_process	The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.
GO:0071345	cellular response to cytokine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
GO:0071346	cellular response to type II interferon	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.
GO:0071347	cellular response to interleukin-1	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
GO:0071348	cellular response to interleukin-11	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.
GO:0071349	cellular response to interleukin-12	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
GO:0071350	cellular response to interleukin-15	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
GO:0071351	cellular response to interleukin-18	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
GO:0071352	cellular response to interleukin-2	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
GO:0071353	cellular response to interleukin-4	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
GO:0071354	cellular response to interleukin-6	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
GO:0071355	cellular response to interleukin-9	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.
GO:0071356	cellular response to tumor necrosis factor	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
GO:0071357	cellular response to type I interferon	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
GO:0071358	cellular response to type III interferon	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.
GO:0071359	cellular response to dsRNA	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
GO:0071360	cellular response to exogenous dsRNA	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
GO:0071361	cellular response to ethanol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
GO:0071362	cellular response to ether	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
GO:0071363	cellular response to growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
GO:0071364	cellular response to epidermal growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
GO:0071365	cellular response to auxin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
GO:0071366	cellular response to indolebutyric acid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.
GO:0071367	cellular response to brassinosteroid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
GO:0071368	cellular response to cytokinin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
GO:0071369	cellular response to ethylene stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
GO:0071370	cellular response to gibberellin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
GO:0071371	cellular response to gonadotropin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
GO:0071372	cellular response to follicle-stimulating hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
GO:0071373	cellular response to luteinizing hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
GO:0071374	cellular response to parathyroid hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
GO:0071375	cellular response to peptide hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
GO:0071376	cellular response to corticotropin-releasing hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
GO:0071377	cellular response to glucagon stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
GO:0071378	cellular response to growth hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
GO:0071379	cellular response to prostaglandin stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.
GO:0071380	cellular response to prostaglandin E stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
GO:0071381	cellular response to prostaglandin F stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.
GO:0071382	cellular response to prostaglandin I stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.
GO:0071383	cellular response to steroid hormone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
GO:0071384	cellular response to corticosteroid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
GO:0071385	cellular response to glucocorticoid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
GO:0071386	cellular response to corticosterone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
GO:0071387	cellular response to cortisol stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
GO:0071388	cellular response to cortisone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.
GO:0071389	cellular response to mineralocorticoid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
GO:0071390	cellular response to ecdysone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
GO:0071391	cellular response to estrogen stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
GO:0071392	cellular response to estradiol stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
GO:0071393	cellular response to progesterone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
GO:0071394	cellular response to testosterone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
GO:0071395	cellular response to jasmonic acid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
GO:0071396	cellular response to lipid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
GO:0071397	cellular response to cholesterol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
GO:0071398	cellular response to fatty acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
GO:0071399	cellular response to linoleic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.
GO:0071400	cellular response to oleic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.
GO:0071401	cellular response to triglyceride	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.
GO:0071402	cellular response to lipoprotein particle stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.
GO:0071403	cellular response to high density lipoprotein particle stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
GO:0071404	cellular response to low-density lipoprotein particle stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
GO:0071405	cellular response to methanol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.
GO:0071406	cellular response to methylmercury	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
GO:0071407	cellular response to organic cyclic compound	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
GO:0071408	cellular response to cycloalkane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.
GO:0071409	cellular response to cycloheximide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
GO:0071410	cellular response to cyclopentenone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.
GO:0071411	cellular response to fluoxetine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
GO:0071412	cellular response to genistein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.
GO:0071413	cellular response to hydroxyisoflavone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.
GO:0071414	cellular response to methotrexate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
GO:0071415	cellular response to purine-containing compound	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
GO:0071416	cellular response to tropane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.
GO:0071417	cellular response to organonitrogen compound	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
GO:0071418	cellular response to amine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
GO:0071419	cellular response to amphetamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
GO:0071420	cellular response to histamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
GO:0071421	manganese ion transmembrane transport	biological_process	A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0071422	succinate transmembrane transport	biological_process	The process in which succinate is transported across a membrane.
GO:0071423	malate transmembrane transport	biological_process	A process in which a malate ion is transported across a membrane.
GO:0071424	rRNA (cytosine-N4-)-methyltransferase activity	molecular_function	Catalysis of the reaction: a cytidine in rRNA + S-adenosyl-L-methionine = an N(4)-methylcytidine in rRNA + H+ + S-adenosyl-L-homocysteine.
GO:0071425	hematopoietic stem cell proliferation	biological_process	The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.
GO:0071432	peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion	biological_process	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.
GO:0071433	cell wall repair	biological_process	A process of cell wall organization that results in the restoration of the cell wall following damage.
GO:0071434	cell chemotaxis to angiotensin	biological_process	The directed movement of a motile cell in response to the presence of angiotensin.
GO:0071439	clathrin complex	cellular_component	A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.
GO:0071443	tDNA binding	molecular_function	Binding to DNA sequences encoding transfer RNA.
GO:0071444	cellular response to pheromone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
GO:0071446	cellular response to salicylic acid stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
GO:0071447	cellular response to hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
GO:0071448	cellular response to alkyl hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.
GO:0071449	cellular response to lipid hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.
GO:0071450	cellular response to oxygen radical	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
GO:0071451	cellular response to superoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
GO:0071452	cellular response to singlet oxygen	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
GO:0071453	cellular response to oxygen levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
GO:0071454	cellular response to anoxia	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
GO:0071455	cellular response to hyperoxia	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
GO:0071456	cellular response to hypoxia	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
GO:0071457	cellular response to ozone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
GO:0071459	protein localization to chromosome, centromeric region	biological_process	Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.
GO:0071460	cellular response to cell-matrix adhesion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.
GO:0071461	cellular response to redox state	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
GO:0071462	cellular response to water stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
GO:0071463	cellular response to humidity	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.
GO:0071464	cellular response to hydrostatic pressure	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
GO:0071465	cellular response to desiccation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
GO:0071466	cellular response to xenobiotic stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:0071467	cellular response to pH	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0071468	cellular response to acidic pH	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0071469	cellular response to alkaline pH	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
GO:0071470	cellular response to osmotic stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
GO:0071471	cellular response to non-ionic osmotic stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
GO:0071472	cellular response to salt stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0071473	cellular response to cation stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
GO:0071474	cellular hyperosmotic response	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
GO:0071475	cellular hyperosmotic salinity response	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0071476	cellular hypotonic response	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
GO:0071477	cellular hypotonic salinity response	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0071478	cellular response to radiation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
GO:0071479	cellular response to ionizing radiation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
GO:0071480	cellular response to gamma radiation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
GO:0071481	cellular response to X-ray	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
GO:0071482	cellular response to light stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
GO:0071483	cellular response to blue light	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
GO:0071484	cellular response to light intensity	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
GO:0071485	cellular response to absence of light	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
GO:0071486	cellular response to high light intensity	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
GO:0071487	cellular response to low light intensity stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
GO:0071488	cellular response to very low light intensity stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
GO:0071489	cellular response to red or far red light	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0071490	cellular response to far red light	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0071491	cellular response to red light	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
GO:0071492	cellular response to UV-A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
GO:0071493	cellular response to UV-B	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
GO:0071494	cellular response to UV-C	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
GO:0071495	cellular response to endogenous stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GO:0071496	cellular response to external stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0071497	cellular response to freezing	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
GO:0071498	cellular response to fluid shear stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
GO:0071499	cellular response to laminar fluid shear stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.
GO:0071500	cellular response to nitrosative stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
GO:0071501	cellular response to sterol depletion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
GO:0071502	cellular response to temperature stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
GO:0071503	response to heparin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
GO:0071504	cellular response to heparin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
GO:0071505	response to mycophenolic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
GO:0071506	cellular response to mycophenolic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
GO:0071507	pheromone response MAPK cascade	biological_process	A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.
GO:0071513	phosphopantothenoylcysteine decarboxylase complex	cellular_component	A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
GO:0071514	genomic imprinting	biological_process	The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.
GO:0071515	mating-type locus imprinting	biological_process	A genomic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.
GO:0071518	autoinducer-2 kinase activity	molecular_function	Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.
GO:0071519	actomyosin contractile ring actin filament bundle assembly	biological_process	A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.
GO:0071520	actomyosin contractile ring assembly actin filament bundle convergence	biological_process	A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.
GO:0071521	Cdc42 GTPase complex	cellular_component	A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signaling pathway.
GO:0071522	ureidoglycine aminohydrolase activity	molecular_function	Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3.
GO:0071524	pyrrolysine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.
GO:0071525	pyrrolysine metabolic process	biological_process	The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.
GO:0071526	semaphorin-plexin signaling pathway	biological_process	The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
GO:0071527	semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	biological_process	The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.
GO:0071528	tRNA re-export from nucleus	biological_process	The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.
GO:0071529	cementum mineralization	biological_process	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.
GO:0071532	ankyrin repeat binding	molecular_function	Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.
GO:0071535	RING-like zinc finger domain binding	molecular_function	Binding to a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.
GO:0071539	protein localization to centrosome	biological_process	A process in which a protein is transported to, or maintained at, the centrosome.
GO:0071540	eukaryotic translation initiation factor 3 complex, eIF3e	cellular_component	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	cellular_component	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.
GO:0071542	dopaminergic neuron differentiation	biological_process	The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
GO:0071543	diphosphoinositol polyphosphate metabolic process	biological_process	The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
GO:0071544	diphosphoinositol polyphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
GO:0071545	inositol phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
GO:0071546	pi-body	cellular_component	A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
GO:0071547	piP-body	cellular_component	A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
GO:0071548	response to dexamethasone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
GO:0071549	cellular response to dexamethasone stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
GO:0071550	death-inducing signaling complex assembly	biological_process	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.
GO:0071551	RIP homotypic interaction motif binding	molecular_function	Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.
GO:0071553	G protein-coupled pyrimidinergic nucleotide receptor activity	molecular_function	Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0071554	cell wall organization or biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
GO:0071555	cell wall organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0071557	histone H3-K27 demethylation	biological_process	The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.
GO:0071558	histone H3K27me2/H3K27me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0071559	response to transforming growth factor beta	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
GO:0071560	cellular response to transforming growth factor beta stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
GO:0071561	nucleus-vacuole junction	cellular_component	An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.
GO:0071562	nucleus-vacuole junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway.
GO:0071563	Myo2p-Vac17p-Vac8p transport complex	cellular_component	A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.
GO:0071564	npBAF complex	cellular_component	A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.
GO:0071565	nBAF complex	cellular_component	A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
GO:0071566	UFM1 activating enzyme activity	molecular_function	Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.
GO:0071567	deUFMylase activity	molecular_function	A thiol-dependent isopeptidase activity that cleaves UFM1 from a target protein to which it is conjugated.
GO:0071568	UFM1 transferase activity	molecular_function	Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.
GO:0071569	protein ufmylation	biological_process	Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
GO:0071570	cement gland development	biological_process	The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.
GO:0071572	histone H3-K56 deacetylation	biological_process	The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.
GO:0071573	shelterin complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.
GO:0071574	protein localization to medial cortex	biological_process	A process in which a protein is transported to, or maintained in, the medial cortex.
GO:0071576	tetrahydrodictyopterin binding	molecular_function	Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.
GO:0071577	zinc ion transmembrane transport	biological_process	A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0071578	zinc ion import across plasma membrane	biological_process	The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0071579	regulation of zinc ion transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071580	regulation of zinc ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.
GO:0071581	regulation of zinc ion transmembrane import	biological_process	Any process that modulates the frequency, rate or extent of zinc ion import.
GO:0071582	negative regulation of zinc ion transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071583	negative regulation of zinc ion transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.
GO:0071584	negative regulation of zinc ion transmembrane import	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.
GO:0071585	detoxification of cadmium ion	biological_process	Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
GO:0071586	CAAX-box protein processing	biological_process	The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.
GO:0071587	CAAX-box protein modification	biological_process	The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.
GO:0071588	hydrogen peroxide mediated signaling pathway	biological_process	The series of molecular signals mediated by the detection of hydrogen peroxide (H2O2).
GO:0071589	pyridine nucleoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.
GO:0071590	nicotinamide riboside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
GO:0071591	nicotinic acid riboside metabolic process	biological_process	The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.
GO:0071592	nicotinic acid riboside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.
GO:0071593	lymphocyte aggregation	biological_process	The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules.
GO:0071594	thymocyte aggregation	biological_process	The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.
GO:0071595	Nem1-Spo7 phosphatase complex	cellular_component	A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.
GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.
GO:0071597	cellular birth scar	cellular_component	Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.
GO:0071598	neuronal ribonucleoprotein granule	cellular_component	A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.
GO:0071599	otic vesicle development	biological_process	The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
GO:0071600	otic vesicle morphogenesis	biological_process	The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
GO:0071601	sphere organelle	cellular_component	A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.
GO:0071602	phytosphingosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.
GO:0071603	endothelial cell-cell adhesion	biological_process	The attachment of an endothelial cell to another endothelial cell via adhesion molecules.
GO:0071604	transforming growth factor beta production	biological_process	The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.
GO:0071605	monocyte chemotactic protein-1 production	biological_process	The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071606	chemokine (C-C motif) ligand 4 production	biological_process	The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071607	macrophage inflammatory protein-1 gamma production	biological_process	The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071608	macrophage inflammatory protein-1 alpha production	biological_process	The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071609	chemokine (C-C motif) ligand 5 production	biological_process	The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071610	chemokine (C-C motif) ligand 1 production	biological_process	The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071611	granulocyte colony-stimulating factor production	biological_process	The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071612	IP-10 production	biological_process	The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071613	granzyme B production	biological_process	The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071614	linoleic acid epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.
GO:0071616	acyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
GO:0071617	lysophospholipid acyltransferase activity	molecular_function	Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.
GO:0071618	lysophosphatidylethanolamine acyltransferase activity	molecular_function	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.
GO:0071621	granulocyte chemotaxis	biological_process	The movement of a granulocyte in response to an external stimulus.
GO:0071622	regulation of granulocyte chemotaxis	biological_process	Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
GO:0071623	negative regulation of granulocyte chemotaxis	biological_process	Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
GO:0071624	positive regulation of granulocyte chemotaxis	biological_process	Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
GO:0071625	vocalization behavior	biological_process	The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
GO:0071626	mastication	biological_process	The process of biting and mashing food with the teeth prior to swallowing.
GO:0071629	cytoplasm protein quality control by the ubiquitin-proteasome system	biological_process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.
GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	biological_process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.
GO:0071631	mating pheromone secretion involved in positive regulation of conjugation with cellular fusion	biological_process	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types.
GO:0071632	optomotor response	biological_process	Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.
GO:0071633	dihydroceramidase activity	molecular_function	Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine.
GO:0071634	regulation of transforming growth factor beta production	biological_process	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.
GO:0071635	negative regulation of transforming growth factor beta production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
GO:0071636	positive regulation of transforming growth factor beta production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
GO:0071637	regulation of monocyte chemotactic protein-1 production	biological_process	Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.
GO:0071640	regulation of macrophage inflammatory protein 1 alpha production	biological_process	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
GO:0071641	negative regulation of macrophage inflammatory protein 1 alpha production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
GO:0071642	positive regulation of macrophage inflammatory protein 1 alpha production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
GO:0071643	regulation of chemokine (C-C motif) ligand 4 production	biological_process	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
GO:0071644	negative regulation of chemokine (C-C motif) ligand 4 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
GO:0071645	positive regulation of chemokine (C-C motif) ligand 4 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
GO:0071646	regulation of macrophage inflammatory protein-1 gamma production	biological_process	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
GO:0071647	negative regulation of macrophage inflammatory protein-1 gamma production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
GO:0071648	positive regulation of macrophage inflammatory protein-1 gamma production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
GO:0071649	regulation of chemokine (C-C motif) ligand 5 production	biological_process	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
GO:0071650	negative regulation of chemokine (C-C motif) ligand 5 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
GO:0071652	regulation of chemokine (C-C motif) ligand 1 production	biological_process	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
GO:0071653	negative regulation of chemokine (C-C motif) ligand 1 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
GO:0071654	positive regulation of chemokine (C-C motif) ligand 1 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
GO:0071655	regulation of granulocyte colony-stimulating factor production	biological_process	Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
GO:0071656	negative regulation of granulocyte colony-stimulating factor production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.
GO:0071657	positive regulation of granulocyte colony-stimulating factor production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
GO:0071658	regulation of IP-10 production	biological_process	Any process that modulates the frequency, rate, or extent of production of IP-10.
GO:0071659	negative regulation of IP-10 production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.
GO:0071660	positive regulation of IP-10 production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of IP-10.
GO:0071661	regulation of granzyme B production	biological_process	Any process that modulates the frequency, rate, or extent of production of granzyme B.
GO:0071662	negative regulation of granzyme B production	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.
GO:0071663	positive regulation of granzyme B production	biological_process	Any process that activates or increases the frequency, rate, or extent of production of granzyme B.
GO:0071664	catenin-TCF7L2 complex	cellular_component	A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
GO:0071665	gamma-catenin-TCF7L2 complex	cellular_component	A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
GO:0071666	Slit-Robo signaling complex	cellular_component	A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.
GO:0071667	DNA/RNA hybrid binding	molecular_function	Binding to a RNA/DNA hybrid.
GO:0071668	plant-type cell wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.
GO:0071669	plant-type cell wall organization or biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.
GO:0071670	smooth muscle cell chemotaxis	biological_process	The directed movement of a smooth muscle cell in response to an external stimulus.
GO:0071671	regulation of smooth muscle cell chemotaxis	biological_process	Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.
GO:0071672	negative regulation of smooth muscle cell chemotaxis	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.
GO:0071673	positive regulation of smooth muscle cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.
GO:0071674	mononuclear cell migration	biological_process	The movement of a mononuclear cell within or between different tissues and organs of the body.
GO:0071675	regulation of mononuclear cell migration	biological_process	Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
GO:0071676	negative regulation of mononuclear cell migration	biological_process	Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
GO:0071677	positive regulation of mononuclear cell migration	biological_process	Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
GO:0071678	olfactory bulb axon guidance	biological_process	The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.
GO:0071679	commissural neuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.
GO:0071680	response to indole-3-methanol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.
GO:0071681	cellular response to indole-3-methanol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.
GO:0071682	endocytic vesicle lumen	cellular_component	The volume enclosed by the membrane of an endocytic vesicle.
GO:0071683	sensory dendrite	cellular_component	A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.
GO:0071684	organism emergence from protective structure	biological_process	The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.
GO:0071685	NADH dehydrogenase complex (plastoquinone)	cellular_component	An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.
GO:0071688	striated muscle myosin thick filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.
GO:0071689	muscle thin filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
GO:0071690	cardiac muscle myosin thick filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.
GO:0071691	cardiac muscle thin filament assembly	biological_process	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.
GO:0071692	protein localization to extracellular region	biological_process	Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
GO:0071693	protein transport within extracellular region	biological_process	The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.
GO:0071694	maintenance of protein location in extracellular region	biological_process	Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.
GO:0071695	anatomical structure maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.
GO:0071696	ectodermal placode development	biological_process	The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
GO:0071697	ectodermal placode morphogenesis	biological_process	The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
GO:0071698	olfactory placode development	biological_process	The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
GO:0071699	olfactory placode morphogenesis	biological_process	The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
GO:0071700	olfactory placode maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
GO:0071701	regulation of MAPK export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.
GO:0071702	organic substance transport	biological_process	The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0071703	detection of organic substance	biological_process	The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal.
GO:0071704	organic substance metabolic process	biological_process	The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0071705	nitrogen compound transport	biological_process	The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071706	tumor necrosis factor superfamily cytokine production	biological_process	The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071707	immunoglobulin heavy chain V-D-J recombination	biological_process	The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
GO:0071708	immunoglobulin light chain V-J recombination	biological_process	The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
GO:0071709	membrane assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a membrane.
GO:0071710	membrane macromolecule biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.
GO:0071711	basement membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
GO:0071712	ER-associated misfolded protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.
GO:0071713	para-aminobenzoyl-glutamate hydrolase activity	molecular_function	Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.
GO:0071714	icosanoid transmembrane transporter activity	molecular_function	Enables the transfer of icosanoids from one side of a membrane to the other.
GO:0071715	icosanoid transport	biological_process	The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.
GO:0071716	leukotriene transport	biological_process	The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.
GO:0071717	thromboxane transport	biological_process	The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
GO:0071718	sodium-independent icosanoid transport	biological_process	The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.
GO:0071719	sodium-independent leukotriene transport	biological_process	The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.
GO:0071720	sodium-independent prostaglandin transport	biological_process	The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071721	sodium-independent thromboxane transport	biological_process	The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
GO:0071722	detoxification of arsenic-containing substance	biological_process	Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.
GO:0071723	lipopeptide binding	molecular_function	Binding to a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids.
GO:0071724	response to diacyl bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.
GO:0071725	response to triacyl bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.
GO:0071726	cellular response to diacyl bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.
GO:0071727	cellular response to triacyl bacterial lipopeptide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.
GO:0071728	beak development	biological_process	The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
GO:0071729	beak morphogenesis	biological_process	The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
GO:0071730	beak formation	biological_process	The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
GO:0071731	response to nitric oxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
GO:0071732	cellular response to nitric oxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
GO:0071734	biotin-[pyruvate-carboxylase] ligase activity	molecular_function	Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase).
GO:0071735	IgG immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071736	IgG immunoglobulin complex, circulating	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071737	IgG B cell receptor complex	cellular_component	An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0071738	IgD immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071739	IgD immunoglobulin complex, circulating	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071740	IgD B cell receptor complex	cellular_component	An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0071741	IgD immunoglobulin complex, GPI-anchored	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.
GO:0071742	IgE immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071743	IgE immunoglobulin complex, circulating	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071744	IgE B cell receptor complex	cellular_component	An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0071745	IgA immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071746	IgA immunoglobulin complex, circulating	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071747	IgA B cell receptor complex	cellular_component	An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0071748	monomeric IgA immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071749	polymeric IgA immunoglobulin complex	cellular_component	A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071750	dimeric IgA immunoglobulin complex	cellular_component	A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071751	secretory IgA immunoglobulin complex	cellular_component	A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.
GO:0071752	secretory dimeric IgA immunoglobulin complex	cellular_component	A dimeric form of secretory IgA immunoglobulin complex.
GO:0071753	IgM immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071754	IgM immunoglobulin complex, circulating	cellular_component	A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.
GO:0071755	IgM B cell receptor complex	cellular_component	An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
GO:0071756	pentameric IgM immunoglobulin complex	cellular_component	A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.
GO:0071757	hexameric IgM immunoglobulin complex	cellular_component	A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.
GO:0071758	IgW immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071759	IgX immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071760	IgY immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
GO:0071761	IgZ immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.
GO:0071762	heavy chain immunoglobulin complex	cellular_component	A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.
GO:0071763	nuclear membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.
GO:0071764	nuclear outer membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.
GO:0071765	nuclear inner membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.
GO:0071766	Actinobacterium-type cell wall biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
GO:0071767	mycolic acid metabolic process	biological_process	The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
GO:0071768	mycolic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
GO:0071769	mycolate cell wall layer assembly	biological_process	The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.
GO:0071770	DIM/DIP cell wall layer assembly	biological_process	The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
GO:0071771	aldehyde decarbonylase activity	molecular_function	Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.
GO:0071772	response to BMP	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
GO:0071773	cellular response to BMP stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
GO:0071774	response to fibroblast growth factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.
GO:0071781	endoplasmic reticulum cisternal network	cellular_component	A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells.
GO:0071782	endoplasmic reticulum tubular network	cellular_component	A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
GO:0071783	endoplasmic reticulum cisternal network organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
GO:0071784	endoplasmic reticulum cisternal network assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
GO:0071785	endoplasmic reticulum cisternal network maintenance	biological_process	The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
GO:0071786	endoplasmic reticulum tubular network organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
GO:0071787	endoplasmic reticulum tubular network formation	biological_process	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
GO:0071788	endoplasmic reticulum tubular network maintenance	biological_process	The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
GO:0071791	chemokine (C-C motif) ligand 5 binding	molecular_function	Binding to chemokine (C-C motif) ligand 5.
GO:0071792	bacillithiol metabolic process	biological_process	The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
GO:0071793	bacillithiol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
GO:0071794	CAP-Gly domain binding	molecular_function	Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.
GO:0071795	K11-linked polyubiquitin modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.
GO:0071796	K6-linked polyubiquitin modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.
GO:0071797	LUBAC complex	cellular_component	A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.
GO:0071798	response to prostaglandin D	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
GO:0071799	cellular response to prostaglandin D stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
GO:0071800	podosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.
GO:0071801	regulation of podosome assembly	biological_process	Any process that modulates the frequency, rate or extent of podosome assembly.
GO:0071802	negative regulation of podosome assembly	biological_process	Any process that stops, prevents or reduces the rate or extent of podosome assembly.
GO:0071803	positive regulation of podosome assembly	biological_process	Any process that activates or increases the rate or extent of podosome assembly.
GO:0071805	potassium ion transmembrane transport	biological_process	A process in which a potassium ion is transported from one side of a membrane to the other.
GO:0071806	protein transmembrane transport	biological_process	The process in which a protein is transported across a membrane.
GO:0071807	replication fork arrest involved in DNA replication termination	biological_process	A replication fork arrest process that contributes to the termination of DNA replication.
GO:0071808	satellite fibril	cellular_component	An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).
GO:0071809	regulation of fever generation by regulation of prostaglandin biosynthesis	biological_process	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
GO:0071810	regulation of fever generation by regulation of prostaglandin secretion	biological_process	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
GO:0071811	positive regulation of fever generation by positive regulation of prostaglandin biosynthesis	biological_process	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion	biological_process	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
GO:0071813	lipoprotein particle binding	molecular_function	Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
GO:0071814	protein-lipid complex binding	molecular_function	Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.
GO:0071815	intermediate-density lipoprotein particle binding	molecular_function	Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.
GO:0071816	tail-anchored membrane protein insertion into ER membrane	biological_process	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
GO:0071817	MMXD complex	cellular_component	A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.
GO:0071818	BAT3 complex	cellular_component	A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.
GO:0071819	DUBm complex	cellular_component	A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.
GO:0071820	N-box binding	molecular_function	Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.
GO:0071821	FANCM-MHF complex	cellular_component	A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.
GO:0071823	protein-carbohydrate complex subunit organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.
GO:0071824	protein-DNA complex organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.
GO:0071825	protein-lipid complex organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.
GO:0071826	protein-RNA complex organization	biological_process	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.
GO:0071827	plasma lipoprotein particle organization	biological_process	A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.
GO:0071828	apolipoprotein E recycling	biological_process	The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.
GO:0071829	plasma lipoprotein particle disassembly	biological_process	The disaggregation of a plasma lipoprotein particle into its constituent components.
GO:0071830	triglyceride-rich lipoprotein particle clearance	biological_process	The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0071831	intermediate-density lipoprotein particle clearance	biological_process	The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0071834	mating pheromone secretion	biological_process	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.
GO:0071835	mating pheromone secretion involved in regulation of conjugation with cellular fusion	biological_process	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
GO:0071836	nectar secretion	biological_process	The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.
GO:0071837	HMG box domain binding	molecular_function	Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.
GO:0071838	cell proliferation in bone marrow	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.
GO:0071839	apoptotic process in bone marrow cell	biological_process	The apoptotic process in cells in the bone marrow.
GO:0071840	cellular component organization or biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0071846	actin filament debranching	biological_process	An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.
GO:0071847	TNFSF11-mediated signaling pathway	biological_process	The series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	biological_process	Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade.
GO:0071852	fungal-type cell wall organization or biogenesis	biological_process	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.
GO:0071853	fungal-type cell wall disassembly	biological_process	A cellular process that results in the breakdown of a fungal-type cell wall.
GO:0071854	cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly	biological_process	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.
GO:0071855	neuropeptide receptor binding	molecular_function	Binding to a neuropeptide receptor.
GO:0071857	beta-endorphin receptor binding	molecular_function	Binding to a beta-endorphin receptor.
GO:0071858	corazonin receptor binding	molecular_function	Binding to a corazonin receptor.
GO:0071859	neuropeptide F receptor binding	molecular_function	Binding to a neuropeptide F receptor.
GO:0071860	proctolin receptor binding	molecular_function	Binding to a proctolin receptor.
GO:0071861	tachykinin receptor binding	molecular_function	Binding to a tachykinin receptor.
GO:0071863	regulation of cell proliferation in bone marrow	biological_process	A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.
GO:0071864	positive regulation of cell proliferation in bone marrow	biological_process	A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
GO:0071865	regulation of apoptotic process in bone marrow cell	biological_process	Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.
GO:0071866	negative regulation of apoptotic process in bone marrow cell	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
GO:0071867	response to monoamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
GO:0071868	cellular response to monoamine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
GO:0071869	response to catecholamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
GO:0071870	cellular response to catecholamine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
GO:0071871	response to epinephrine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.
GO:0071872	cellular response to epinephrine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.
GO:0071873	response to norepinephrine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.
GO:0071874	cellular response to norepinephrine stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.
GO:0071875	adrenergic receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0071877	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
GO:0071878	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
GO:0071879	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	biological_process	An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
GO:0071881	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	biological_process	An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor, and ending with the regulation of a downstream cellular process.
GO:0071882	phospholipase C-activating adrenergic receptor signaling pathway	biological_process	A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0071883	MAPK-activating adrenergic receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.
GO:0071885	N-terminal protein N-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding	molecular_function	Binding to the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.
GO:0071887	leukocyte apoptotic process	biological_process	Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0071888	macrophage apoptotic process	biological_process	Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.
GO:0071889	14-3-3 protein binding	molecular_function	Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
GO:0071890	bicarbonate binding	molecular_function	Binding to bicarbonate ions (CHO3-).
GO:0071891	N-terminal peptidyl-proline dimethylation involved in translation	biological_process	An N-terminal peptidyl-proline dimethylation process that contributes to translation.
GO:0071892	thrombocyte activation	biological_process	A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	biological_process	A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals.
GO:0071895	odontoblast differentiation	biological_process	The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.
GO:0071896	protein localization to adherens junction	biological_process	Any process in which a protein is transported to, and/or maintained at the adherens junction.
GO:0071897	DNA biosynthetic process	biological_process	The biosynthetic process resulting in the formation of DNA.
GO:0071900	regulation of protein serine/threonine kinase activity	biological_process	Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.
GO:0071901	negative regulation of protein serine/threonine kinase activity	biological_process	Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.
GO:0071902	positive regulation of protein serine/threonine kinase activity	biological_process	Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
GO:0071903	protein N-linked N-acetylglucosaminylation via asparagine	biological_process	A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.
GO:0071904	protein N-linked N-acetylgalactosaminylation via asparagine	biological_process	A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue.
GO:0071905	protein N-linked glucosylation via asparagine	biological_process	A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.
GO:0071906	CRD domain binding	molecular_function	Binding to a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.
GO:0071907	determination of digestive tract left/right asymmetry	biological_process	Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.
GO:0071908	determination of intestine left/right asymmetry	biological_process	Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.
GO:0071909	determination of stomach left/right asymmetry	biological_process	Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.
GO:0071910	determination of liver left/right asymmetry	biological_process	Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.
GO:0071911	synchronous neurotransmitter secretion	biological_process	Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.
GO:0071912	asynchronous neurotransmitter secretion	biological_process	Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.
GO:0071913	citrate secondary active transmembrane transporter activity	molecular_function	Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:0071914	prominosome	cellular_component	An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.
GO:0071915	protein-lysine lysylation	biological_process	The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
GO:0071916	dipeptide transmembrane transporter activity	molecular_function	Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
GO:0071917	triose-phosphate transmembrane transporter activity	molecular_function	Enables the transfer of a triose phosphate from one side of a membrane to the other.
GO:0071918	urea transmembrane transport	biological_process	The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0071919	G-quadruplex DNA formation	biological_process	A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.
GO:0071920	cleavage body	cellular_component	A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
GO:0071921	cohesin loading	biological_process	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA.
GO:0071922	regulation of cohesin loading	biological_process	Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
GO:0071923	negative regulation of cohesin loading	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
GO:0071924	chemokine (C-C motif) ligand 22 production	biological_process	The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071925	thymic stromal lymphopoietin production	biological_process	The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071926	endocannabinoid signaling pathway	biological_process	The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.
GO:0071927	octopamine signaling pathway	biological_process	The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.
GO:0071928	tyramine signaling pathway	biological_process	The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.
GO:0071929	alpha-tubulin acetylation	biological_process	The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	biological_process	Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.
GO:0071931	positive regulation of transcription involved in G1/S transition of mitotic cell cycle	biological_process	Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
GO:0071932	replication fork reversal	biological_process	Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.
GO:0071933	Arp2/3 complex binding	molecular_function	Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
GO:0071934	thiamine transmembrane transport	biological_process	The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
GO:0071935	octopamine signaling pathway involved in response to food	biological_process	The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.
GO:0071938	vitamin A transport	biological_process	The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.
GO:0071939	vitamin A import into cell	biological_process	The directed movement of vitamin A from outside of a cell, across the plasma membrane and into the cytosol. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.
GO:0071940	fungal-type cell wall assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.
GO:0071941	nitrogen cycle metabolic process	biological_process	A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.
GO:0071942	XPC complex	cellular_component	A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.
GO:0071943	Myc-Max complex	cellular_component	A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.
GO:0071944	cell periphery	cellular_component	The broad region around and including the plasma membrane of a cell,  encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.
GO:0071945	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	biological_process	A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.
GO:0071946	cis-acting DNA replication termination	biological_process	A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	biological_process	The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.
GO:0071948	activation-induced B cell apoptotic process	biological_process	B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.
GO:0071949	FAD binding	molecular_function	Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0071950	FADH2 binding	molecular_function	Binding to the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	biological_process	The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).
GO:0071952	conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA	biological_process	The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.
GO:0071953	elastic fiber	cellular_component	An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.
GO:0071954	chemokine (C-C motif) ligand 11 production	biological_process	The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0071955	recycling endosome to Golgi transport	biological_process	The directed movement of substances from recycling endosomes to the Golgi.
GO:0071957	old mitotic spindle pole body	cellular_component	The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.
GO:0071958	new mitotic spindle pole body	cellular_component	The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.
GO:0071959	maintenance of mitotic sister chromatid cohesion, arms	biological_process	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
GO:0071960	maintenance of mitotic sister chromatid cohesion, centromeric	biological_process	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
GO:0071961	mitotic sister chromatid cohesion, arms	biological_process	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.
GO:0071962	mitotic sister chromatid cohesion, centromeric	biological_process	The cell cycle process in which centromeres of sister chromatids are joined during mitosis.
GO:0071963	establishment or maintenance of cell polarity regulating cell shape	biological_process	Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
GO:0071964	establishment of cell polarity regulating cell shape	biological_process	Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.
GO:0071965	multicellular organismal locomotion	biological_process	Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.
GO:0071966	fungal-type cell wall polysaccharide metabolic process	biological_process	The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.
GO:0071967	lipopolysaccharide core heptosyltransferase activity	molecular_function	Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.
GO:0071968	lipid A-core heptosyltransferase activity	molecular_function	Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.
GO:0071969	fungal-type cell wall (1->3)-beta-D-glucan metabolic process	biological_process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.
GO:0071970	fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.
GO:0071971	extracellular exosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.
GO:0071972	peptidoglycan L,D-transpeptidase activity	molecular_function	Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.
GO:0071973	bacterial-type flagellum-dependent cell motility	biological_process	Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
GO:0071975	cell swimming	biological_process	Cell motility that results in the smooth movement of a cell through a liquid medium.
GO:0071976	cell gliding	biological_process	Cell motility that results in the smooth movement of a cell along a solid surface.
GO:0071977	bacterial-type flagellum-dependent swimming motility	biological_process	Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.
GO:0071978	bacterial-type flagellum-dependent swarming motility	biological_process	Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
GO:0071979	cytoskeleton-mediated cell swimming	biological_process	Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.
GO:0071980	cell surface adhesin-mediated gliding motility	biological_process	Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.
GO:0071981	exit from diapause	biological_process	The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
GO:0071982	maintenance of diapause	biological_process	The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
GO:0071983	exit from reproductive diapause	biological_process	The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0071984	maintenance of reproductive diapause	biological_process	The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
GO:0071985	multivesicular body sorting pathway	biological_process	A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.
GO:0071986	Ragulator complex	cellular_component	A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signaling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified).
GO:0071987	WD40-repeat domain binding	molecular_function	Binding to a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.
GO:0071988	protein localization to spindle pole body	biological_process	A process in which a protein is transported to, or maintained at, the spindle pole body.
GO:0071989	establishment of protein localization to spindle pole body	biological_process	The directed movement of a protein to a specific location at the spindle pole body.
GO:0071990	maintenance of protein location to spindle pole body	biological_process	Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.
GO:0071993	phytochelatin transport	biological_process	The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
GO:0071994	phytochelatin transmembrane transport	biological_process	The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
GO:0071995	phytochelatin import into vacuole	biological_process	The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
GO:0071996	glutathione transmembrane import into vacuole	biological_process	The directed movement of glutathione into the vacuole across the vacuolar membrane.
GO:0071998	ascospore release from ascus	biological_process	A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.
GO:0071999	extracellular polysaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures.
GO:0072000	extracellular polysaccharide catabolic process involved in ascospore release from ascus	biological_process	The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.
GO:0072001	renal system development	biological_process	The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.
GO:0072002	Malpighian tubule development	biological_process	The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
GO:0072003	kidney rudiment formation	biological_process	The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0072004	kidney field specification	biological_process	The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.
GO:0072005	maintenance of kidney identity	biological_process	The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0072006	nephron development	biological_process	The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
GO:0072007	mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.
GO:0072008	glomerular mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.
GO:0072009	nephron epithelium development	biological_process	The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.
GO:0072010	glomerular epithelium development	biological_process	The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
GO:0072011	glomerular endothelium development	biological_process	The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.
GO:0072012	glomerulus vasculature development	biological_process	The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.
GO:0072013	glomus development	biological_process	The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.
GO:0072014	proximal tubule development	biological_process	The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
GO:0072015	podocyte development	biological_process	The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.
GO:0072016	glomerular parietal epithelial cell development	biological_process	The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0072017	distal tubule development	biological_process	The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
GO:0072019	proximal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.
GO:0072020	proximal straight tubule development	biological_process	The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.
GO:0072021	ascending thin limb development	biological_process	The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.
GO:0072022	descending thin limb development	biological_process	The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.
GO:0072023	thick ascending limb development	biological_process	The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.
GO:0072024	macula densa development	biological_process	The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.
GO:0072025	distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.
GO:0072027	connecting tubule development	biological_process	The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.
GO:0072028	nephron morphogenesis	biological_process	The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.
GO:0072029	long nephron development	biological_process	The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.
GO:0072030	short nephron development	biological_process	The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.
GO:0072031	proximal convoluted tubule segment 1 development	biological_process	The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
GO:0072032	proximal convoluted tubule segment 2 development	biological_process	The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.
GO:0072033	renal vesicle formation	biological_process	The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
GO:0072034	renal vesicle induction	biological_process	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.
GO:0072035	pre-tubular aggregate formation	biological_process	The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.
GO:0072036	mesenchymal to epithelial transition involved in renal vesicle formation	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.
GO:0072037	mesenchymal stem cell differentiation involved in nephron morphogenesis	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis	biological_process	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0072039	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	biological_process	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
GO:0072040	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	biological_process	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
GO:0072041	positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	biological_process	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
GO:0072042	regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.
GO:0072043	regulation of pre-tubular aggregate formation by cell-cell signaling	biological_process	Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.
GO:0072044	collecting duct development	biological_process	The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
GO:0072045	convergent extension involved in nephron morphogenesis	biological_process	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.
GO:0072046	establishment of planar polarity involved in nephron morphogenesis	biological_process	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.
GO:0072047	proximal/distal pattern formation involved in nephron development	biological_process	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
GO:0072048	renal system pattern specification	biological_process	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.
GO:0072049	comma-shaped body morphogenesis	biological_process	The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.
GO:0072050	S-shaped body morphogenesis	biological_process	The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.
GO:0072051	juxtaglomerular apparatus development	biological_process	The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.
GO:0072052	juxtaglomerulus cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.
GO:0072053	renal inner medulla development	biological_process	The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.
GO:0072054	renal outer medulla development	biological_process	The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.
GO:0072055	renal cortex development	biological_process	The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.
GO:0072056	pyramid development	biological_process	The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.
GO:0072057	inner stripe development	biological_process	The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.
GO:0072058	outer stripe development	biological_process	The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.
GO:0072059	cortical collecting duct development	biological_process	The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.
GO:0072060	outer medullary collecting duct development	biological_process	The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.
GO:0072061	inner medullary collecting duct development	biological_process	The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.
GO:0072062	proximal convoluted tubule segment 1 cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.
GO:0072063	short descending thin limb development	biological_process	The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.
GO:0072064	long descending thin limb development	biological_process	The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.
GO:0072065	long descending thin limb bend development	biological_process	The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.
GO:0072066	prebend segment development	biological_process	The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
GO:0072067	early distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.
GO:0072068	late distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
GO:0072069	DCT cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.
GO:0072070	loop of Henle development	biological_process	The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.
GO:0072071	kidney interstitial fibroblast differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.
GO:0072072	kidney stroma development	biological_process	The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.
GO:0072073	kidney epithelium development	biological_process	The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
GO:0072074	kidney mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
GO:0072075	metanephric mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
GO:0072076	nephrogenic mesenchyme development	biological_process	The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
GO:0072077	renal vesicle morphogenesis	biological_process	The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
GO:0072078	nephron tubule morphogenesis	biological_process	The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
GO:0072079	nephron tubule formation	biological_process	The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
GO:0072080	nephron tubule development	biological_process	The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
GO:0072081	specification of nephron tubule identity	biological_process	The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.
GO:0072082	specification of proximal tubule identity	biological_process	The process in which the proximal tubule of the kidney nephron acquires its identity.
GO:0072084	specification of distal tubule identity	biological_process	The process in which the distal tubule of the kidney nephron acquires its identity.
GO:0072085	specification of connecting tubule identity	biological_process	The process in which the connecting tubule of the kidney nephron acquires its identity.
GO:0072086	specification of loop of Henle identity	biological_process	The process in which the loop of Henle of the kidney nephron acquires its identity.
GO:0072087	renal vesicle development	biological_process	The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
GO:0072088	nephron epithelium morphogenesis	biological_process	The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.
GO:0072089	stem cell proliferation	biological_process	The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
GO:0072090	mesenchymal stem cell proliferation involved in nephron morphogenesis	biological_process	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.
GO:0072091	regulation of stem cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
GO:0072092	ureteric bud invasion	biological_process	The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.
GO:0072093	metanephric renal vesicle formation	biological_process	The developmental process pertaining to the initial formation of the metanephros.
GO:0072094	metanephric renal vesicle induction	biological_process	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.
GO:0072095	regulation of branch elongation involved in ureteric bud branching	biological_process	Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
GO:0072096	negative regulation of branch elongation involved in ureteric bud branching	biological_process	Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
GO:0072098	anterior/posterior pattern specification involved in kidney development	biological_process	The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
GO:0072099	anterior/posterior pattern specification involved in ureteric bud development	biological_process	The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
GO:0072100	specification of ureteric bud anterior/posterior symmetry	biological_process	The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
GO:0072102	glomerulus morphogenesis	biological_process	The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
GO:0072103	glomerulus vasculature morphogenesis	biological_process	The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.
GO:0072104	glomerular capillary formation	biological_process	The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
GO:0072105	ureteric peristalsis	biological_process	A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.
GO:0072106	regulation of ureteric bud formation	biological_process	Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.
GO:0072107	positive regulation of ureteric bud formation	biological_process	Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	biological_process	Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
GO:0072109	glomerular mesangium development	biological_process	The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.
GO:0072110	glomerular mesangial cell proliferation	biological_process	The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.
GO:0072111	cell proliferation involved in kidney development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.
GO:0072112	podocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.
GO:0072113	head kidney development	biological_process	The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.
GO:0072114	pronephros morphogenesis	biological_process	The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
GO:0072115	head kidney morphogenesis	biological_process	The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
GO:0072116	pronephros formation	biological_process	The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
GO:0072117	head kidney formation	biological_process	The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
GO:0072118	pronephros structural organization	biological_process	The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
GO:0072119	head kidney structural organization	biological_process	The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
GO:0072120	pronephros maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
GO:0072121	head kidney maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
GO:0072122	extraglomerular mesangial cell proliferation	biological_process	The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
GO:0072123	intraglomerular mesangial cell proliferation	biological_process	The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
GO:0072124	regulation of glomerular mesangial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.
GO:0072125	negative regulation of glomerular mesangial cell proliferation	biological_process	Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.
GO:0072126	positive regulation of glomerular mesangial cell proliferation	biological_process	Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
GO:0072127	renal capsule development	biological_process	The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
GO:0072128	renal capsule morphogenesis	biological_process	The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
GO:0072129	renal capsule formation	biological_process	The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
GO:0072130	renal capsule specification	biological_process	The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0072131	kidney mesenchyme morphogenesis	biological_process	The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
GO:0072132	mesenchyme morphogenesis	biological_process	The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.
GO:0072133	metanephric mesenchyme morphogenesis	biological_process	The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
GO:0072134	nephrogenic mesenchyme morphogenesis	biological_process	The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
GO:0072135	kidney mesenchymal cell proliferation	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.
GO:0072137	condensed mesenchymal cell proliferation	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.
GO:0072139	glomerular parietal epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0072140	DCT cell development	biological_process	The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.
GO:0072141	renal interstitial fibroblast development	biological_process	The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.
GO:0072142	juxtaglomerulus cell development	biological_process	The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.
GO:0072143	mesangial cell development	biological_process	The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.
GO:0072144	glomerular mesangial cell development	biological_process	The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.
GO:0072145	proximal convoluted tubule segment 1 cell development	biological_process	The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.
GO:0072146	DCT cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.
GO:0072147	glomerular parietal epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
GO:0072148	epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.
GO:0072149	podocyte cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.
GO:0072150	juxtaglomerulus cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.
GO:0072151	mesangial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.
GO:0072152	glomerular mesangial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.
GO:0072153	renal interstitial fibroblast fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.
GO:0072154	proximal convoluted tubule segment 1 cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.
GO:0072155	epithelial cell migration involved in nephron tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.
GO:0072156	distal tubule morphogenesis	biological_process	The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
GO:0072157	epithelial cell migration involved in distal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.
GO:0072158	proximal tubule morphogenesis	biological_process	The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
GO:0072159	epithelial cell migration involved in proximal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.
GO:0072160	nephron tubule epithelial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
GO:0072161	mesenchymal cell differentiation involved in kidney development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.
GO:0072162	metanephric mesenchymal cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
GO:0072163	mesonephric epithelium development	biological_process	The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
GO:0072164	mesonephric tubule development	biological_process	The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
GO:0072165	anterior mesonephric tubule development	biological_process	The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.
GO:0072166	posterior mesonephric tubule development	biological_process	The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.
GO:0072167	specification of mesonephric tubule identity	biological_process	The process in which the tubules of the mesonephros acquire their identity.
GO:0072168	specification of anterior mesonephric tubule identity	biological_process	The process in which the tubules of the anterior mesonephros acquire their identity.
GO:0072169	specification of posterior mesonephric tubule identity	biological_process	The process in which the tubules of the posterior mesonephros acquire their identity.
GO:0072170	metanephric tubule development	biological_process	The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.
GO:0072171	mesonephric tubule morphogenesis	biological_process	The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
GO:0072172	mesonephric tubule formation	biological_process	The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
GO:0072173	metanephric tubule morphogenesis	biological_process	The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
GO:0072174	metanephric tubule formation	biological_process	The developmental process pertaining to the initial formation of a metanephric tubule.
GO:0072175	epithelial tube formation	biological_process	The developmental process pertaining to the initial formation of an epithelial tube.
GO:0072176	nephric duct development	biological_process	The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.
GO:0072177	mesonephric duct development	biological_process	The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.
GO:0072178	nephric duct morphogenesis	biological_process	The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.
GO:0072179	nephric duct formation	biological_process	The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.
GO:0072180	mesonephric duct morphogenesis	biological_process	The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.
GO:0072181	mesonephric duct formation	biological_process	The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.
GO:0072182	regulation of nephron tubule epithelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	biological_process	Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.
GO:0072184	renal vesicle progenitor cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.
GO:0072185	metanephric cap development	biological_process	The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
GO:0072186	metanephric cap morphogenesis	biological_process	The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
GO:0072187	metanephric cap formation	biological_process	The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
GO:0072188	metanephric cap specification	biological_process	The process in which the metanephric cap acquires its identity.
GO:0072189	ureter development	biological_process	The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.
GO:0072190	ureter urothelium development	biological_process	The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.
GO:0072191	ureter smooth muscle development	biological_process	The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.
GO:0072192	ureter epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.
GO:0072193	ureter smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.
GO:0072194	kidney smooth muscle tissue development	biological_process	The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.
GO:0072195	kidney smooth muscle cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.
GO:0072196	proximal/distal pattern formation involved in pronephric nephron development	biological_process	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
GO:0072197	ureter morphogenesis	biological_process	The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
GO:0072198	mesenchymal cell proliferation involved in ureter development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	biological_process	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0072201	negative regulation of mesenchymal cell proliferation	biological_process	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
GO:0072202	cell differentiation involved in metanephros development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.
GO:0072203	cell proliferation involved in metanephros development	biological_process	The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.
GO:0072204	cell-cell signaling involved in metanephros development	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.
GO:0072205	metanephric collecting duct development	biological_process	The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
GO:0072206	metanephric juxtaglomerular apparatus development	biological_process	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.
GO:0072207	metanephric epithelium development	biological_process	The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
GO:0072208	metanephric smooth muscle tissue development	biological_process	The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.
GO:0072209	metanephric mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.
GO:0072210	metanephric nephron development	biological_process	The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
GO:0072211	metanephric pyramids development	biological_process	The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.
GO:0072213	metanephric capsule development	biological_process	The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
GO:0072214	metanephric cortex development	biological_process	The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.
GO:0072215	regulation of metanephros development	biological_process	Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0072216	positive regulation of metanephros development	biological_process	Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0072217	negative regulation of metanephros development	biological_process	Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0072218	metanephric ascending thin limb development	biological_process	The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.
GO:0072219	metanephric cortical collecting duct development	biological_process	The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.
GO:0072220	metanephric descending thin limb development	biological_process	The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.
GO:0072221	metanephric distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.
GO:0072222	metanephric early distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.
GO:0072223	metanephric glomerular mesangium development	biological_process	The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.
GO:0072224	metanephric glomerulus development	biological_process	The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
GO:0072225	metanephric late distal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
GO:0072226	metanephric long descending thin limb bend development	biological_process	The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.
GO:0072227	metanephric macula densa development	biological_process	The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.
GO:0072228	metanephric prebend segment development	biological_process	The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
GO:0072229	metanephric proximal convoluted tubule development	biological_process	The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.
GO:0072230	metanephric proximal straight tubule development	biological_process	The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.
GO:0072231	metanephric proximal convoluted tubule segment 1 development	biological_process	The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
GO:0072232	metanephric proximal convoluted tubule segment 2 development	biological_process	The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.
GO:0072233	metanephric thick ascending limb development	biological_process	The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.
GO:0072234	metanephric nephron tubule development	biological_process	The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
GO:0072235	metanephric distal tubule development	biological_process	The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.
GO:0072236	metanephric loop of Henle development	biological_process	The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.
GO:0072237	metanephric proximal tubule development	biological_process	The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.
GO:0072238	metanephric long nephron development	biological_process	The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.
GO:0072239	metanephric glomerulus vasculature development	biological_process	The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.
GO:0072240	metanephric DCT cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.
GO:0072241	metanephric DCT cell development	biological_process	The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.
GO:0072242	metanephric DCT cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.
GO:0072243	metanephric nephron epithelium development	biological_process	The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.
GO:0072244	metanephric glomerular epithelium development	biological_process	The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
GO:0072245	metanephric glomerular parietal epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0072246	metanephric glomerular parietal epithelial cell development	biological_process	The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
GO:0072247	metanephric glomerular parietal epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
GO:0072248	metanephric podocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
GO:0072249	metanephric podocyte development	biological_process	The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
GO:0072250	metanephric podocyte cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
GO:0072251	metanephric juxtaglomerulus cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.
GO:0072252	metanephric juxtaglomerulus cell development	biological_process	The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.
GO:0072253	metanephric juxtaglomerulus cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.
GO:0072254	metanephric glomerular mesangial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.
GO:0072255	metanephric glomerular mesangial cell development	biological_process	The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.
GO:0072256	metanephric glomerular mesangial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.
GO:0072257	metanephric nephron tubule epithelial cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.
GO:0072258	metanephric interstitial fibroblast differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.
GO:0072259	metanephric interstitial fibroblast development	biological_process	The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.
GO:0072260	metanephric interstitial fibroblast fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.
GO:0072261	metanephric extraglomerular mesangial cell proliferation involved in metanephros development	biological_process	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	biological_process	The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.
GO:0072263	metanephric intraglomerular mesangial cell proliferation	biological_process	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
GO:0072264	metanephric glomerular endothelium development	biological_process	The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.
GO:0072265	metanephric capsule morphogenesis	biological_process	The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
GO:0072266	metanephric capsule formation	biological_process	The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
GO:0072267	metanephric capsule specification	biological_process	The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0072268	pattern specification involved in metanephros development	biological_process	Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.
GO:0072269	metanephric long descending thin limb development	biological_process	The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.
GO:0072270	metanephric short nephron development	biological_process	The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.
GO:0072271	metanephric short descending thin limb development	biological_process	The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	biological_process	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
GO:0072273	metanephric nephron morphogenesis	biological_process	The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.
GO:0072274	metanephric glomerular basement membrane development	biological_process	The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.
GO:0072275	metanephric glomerulus morphogenesis	biological_process	The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
GO:0072276	metanephric glomerulus vasculature morphogenesis	biological_process	The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.
GO:0072277	metanephric glomerular capillary formation	biological_process	The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
GO:0072278	metanephric comma-shaped body morphogenesis	biological_process	The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
GO:0072279	convergent extension involved in metanephric nephron morphogenesis	biological_process	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.
GO:0072280	establishment of planar polarity involved in metanephric nephron morphogenesis	biological_process	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.
GO:0072281	mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0072282	metanephric nephron tubule morphogenesis	biological_process	The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
GO:0072283	metanephric renal vesicle morphogenesis	biological_process	The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
GO:0072284	metanephric S-shaped body morphogenesis	biological_process	The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	biological_process	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.
GO:0072286	metanephric connecting tubule development	biological_process	The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.
GO:0072287	metanephric distal tubule morphogenesis	biological_process	The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.
GO:0072288	metanephric proximal tubule morphogenesis	biological_process	The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.
GO:0072289	metanephric nephron tubule formation	biological_process	The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.
GO:0072290	epithelial cell migration involved in metanephric nephron tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.
GO:0072291	epithelial cell migration involved in metanephric distal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.
GO:0072292	epithelial cell migration involved in metanephric proximal tubule morphogenesis	biological_process	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.
GO:0072293	specification of metanephric nephron tubule identity	biological_process	The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.
GO:0072294	specification of metanephric connecting tubule identity	biological_process	The process in which the connecting tubule of the metanephric nephron acquires its identity.
GO:0072295	specification of metanephric distal tubule identity	biological_process	The process in which the distal tubule of the metanephric nephron acquires its identity.
GO:0072296	specification of metanephric loop of Henle identity	biological_process	The process in which the loop of Henle of the metanephric nephron acquires its identity.
GO:0072297	specification of metanephric proximal tubule identity	biological_process	The process in which the proximal tubule of the metanephric nephron acquires its identity.
GO:0072298	regulation of metanephric glomerulus development	biological_process	Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
GO:0072299	negative regulation of metanephric glomerulus development	biological_process	Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
GO:0072300	positive regulation of metanephric glomerulus development	biological_process	Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	biological_process	Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	biological_process	Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
GO:0072304	regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	biological_process	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
GO:0072305	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	biological_process	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
GO:0072306	positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	biological_process	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
GO:0072308	negative regulation of metanephric nephron tubule epithelial cell differentiation	biological_process	Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis	biological_process	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0072310	glomerular epithelial cell development	biological_process	The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
GO:0072311	glomerular epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
GO:0072312	metanephric glomerular epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
GO:0072313	metanephric glomerular epithelial cell development	biological_process	The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
GO:0072314	glomerular epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
GO:0072315	metanephric glomerular epithelial cell fate commitment	biological_process	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
GO:0072316	alpha-glucan catabolic process involved in ascospore release from ascus	biological_process	The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.
GO:0072318	clathrin coat disassembly	biological_process	The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.
GO:0072319	vesicle uncoating	biological_process	A protein depolymerization process that results in the disassembly of vesicle coat proteins.
GO:0072320	volume-sensitive chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
GO:0072322	protein transport across periplasmic space	biological_process	The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.
GO:0072324	ascus epiplasm	cellular_component	Ascus cytoplasm that is not packaged into ascospores.
GO:0072325	vulval cell fate commitment	biological_process	The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
GO:0072326	vulval cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
GO:0072327	vulval cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
GO:0072328	alkene binding	molecular_function	Binding to an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
GO:0072329	monocarboxylic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.
GO:0072330	monocarboxylic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.
GO:0072331	signal transduction by p53 class mediator	biological_process	An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
GO:0072334	UDP-galactose transmembrane transport	biological_process	The process in which UDP-galactose is transported across a membrane.
GO:0072335	regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	biological_process	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0072336	negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	biological_process	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0072337	modified amino acid transport	biological_process	The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0072338	lactam metabolic process	biological_process	The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
GO:0072339	lactam biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
GO:0072340	lactam catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
GO:0072341	modified amino acid binding	molecular_function	Binding to a modified amino acid.
GO:0072342	response to anion stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.
GO:0072343	pancreatic stellate cell proliferation	biological_process	The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.
GO:0072344	rescue of stalled ribosome	biological_process	A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.
GO:0072345	NAADP-sensitive calcium-release channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.
GO:0072346	cADPR-sensitive calcium-release channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.
GO:0072347	response to anesthetic	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
GO:0072348	sulfur compound transport	biological_process	The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0072349	modified amino acid transmembrane transporter activity	molecular_function	Enables the transfer of modified amino acids from one side of a membrane to the other.
GO:0072350	tricarboxylic acid metabolic process	biological_process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).
GO:0072351	tricarboxylic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
GO:0072352	tricarboxylic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
GO:0072354	histone H3T3 kinase activity	molecular_function	Catalysis of the reaction: histone H3-threonine (position 3) + ATP = histone H3-phosphothreonine (position 3) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 3 of histone H3.
GO:0072356	chromosome passenger complex localization to kinetochore	biological_process	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.
GO:0072357	PTW/PP1 phosphatase complex	cellular_component	A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
GO:0072359	circulatory system development	biological_process	The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
GO:0072360	vascular cord development	biological_process	The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.
GO:0072371	histone H2AS121 kinase activity	molecular_function	Catalysis of the reaction: histone H2A-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A.
GO:0072373	alpha-carotene epsilon hydroxylase activity	molecular_function	Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.
GO:0072374	carotene epsilon hydroxylase activity	molecular_function	Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.
GO:0072375	medium-term memory	biological_process	The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
GO:0072376	protein activation cascade	biological_process	A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.
GO:0072377	blood coagulation, common pathway	biological_process	A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.
GO:0072378	blood coagulation, fibrin clot formation	biological_process	A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
GO:0072379	ER membrane insertion complex	cellular_component	A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.
GO:0072380	TRC complex	cellular_component	A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.
GO:0072381	positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	biological_process	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0072382	minus-end-directed vesicle transport along microtubule	biological_process	The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
GO:0072383	plus-end-directed vesicle transport along microtubule	biological_process	The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
GO:0072384	organelle transport along microtubule	biological_process	The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
GO:0072385	minus-end-directed organelle transport along microtubule	biological_process	The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
GO:0072386	plus-end-directed organelle transport along microtubule	biological_process	The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
GO:0072387	flavin adenine dinucleotide metabolic process	biological_process	The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0072388	flavin adenine dinucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0072389	flavin adenine dinucleotide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
GO:0072390	phenol metabolic process	biological_process	The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
GO:0072391	phenol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
GO:0072392	phenol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
GO:0072393	microtubule anchoring at microtubule organizing center	biological_process	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.
GO:0072396	response to cell cycle checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.
GO:0072398	signal transduction involved in cytokinesis checkpoint	biological_process	A signal transduction process that contributes to a cytokinesis checkpoint.
GO:0072399	response to cytokinesis checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.
GO:0072402	response to DNA integrity checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.
GO:0072410	response to meiotic cell cycle checkpoint signaling	biological_process	A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.
GO:0072414	response to mitotic cell cycle checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.
GO:0072417	response to spindle checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of spindle checkpoint signaling.
GO:0072423	response to DNA damage checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.
GO:0072426	response to G2 DNA damage checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.
GO:0072429	response to intra-S DNA damage checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.
GO:0072432	response to G1 DNA damage checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.
GO:0072435	response to mitotic G2 DNA damage checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.
GO:0072438	response to DNA replication checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.
GO:0072441	response to meiotic DNA replication checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.
GO:0072444	response to mitotic DNA replication checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.
GO:0072449	response to G1 cell size control checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.
GO:0072452	response to G2 transition size control checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.
GO:0072461	response to meiotic recombination checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.
GO:0072464	response to meiotic spindle assembly checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.
GO:0072470	response to cell size control checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.
GO:0072476	response to mitotic spindle checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.
GO:0072479	response to mitotic cell cycle spindle assembly checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.
GO:0072482	response to mitotic cell cycle spindle orientation checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.
GO:0072485	response to spindle assembly checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.
GO:0072487	MSL complex	cellular_component	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3.
GO:0072488	ammonium transmembrane transport	biological_process	The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
GO:0072489	methylammonium transmembrane transport	biological_process	The process in which methylammonium is transported across a membrane.
GO:0072490	toluene-containing compound metabolic process	biological_process	The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.
GO:0072491	toluene-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.
GO:0072492	host cell mitochondrial intermembrane space	cellular_component	The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.
GO:0072493	host cell endosome lumen	cellular_component	The volume enclosed by the membranes of the host cell endosome.
GO:0072494	host multivesicular body	cellular_component	A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
GO:0072495	host cell Cajal body	cellular_component	A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.
GO:0072496	Pup transferase activity	molecular_function	Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.
GO:0072497	mesenchymal stem cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0072498	embryonic skeletal joint development	biological_process	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
GO:0072499	photoreceptor cell axon guidance	biological_process	The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
GO:0072514	trehalose transport in response to water deprivation	biological_process	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.
GO:0072515	trehalose transport in response to desiccation	biological_process	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.
GO:0072517	host cell viral assembly compartment	cellular_component	A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.
GO:0072518	Rho-dependent protein serine/threonine kinase activity	molecular_function	Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
GO:0072520	seminiferous tubule development	biological_process	The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
GO:0072521	purine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
GO:0072522	purine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
GO:0072523	purine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
GO:0072524	pyridine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
GO:0072525	pyridine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
GO:0072526	pyridine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
GO:0072527	pyrimidine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
GO:0072528	pyrimidine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
GO:0072529	pyrimidine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
GO:0072530	purine-containing compound transmembrane transport	biological_process	The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.
GO:0072531	pyrimidine-containing compound transmembrane transport	biological_process	The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.
GO:0072532	tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity	molecular_function	Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.
GO:0072533	tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity	molecular_function	Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.
GO:0072534	perineuronal net	cellular_component	A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.
GO:0072535	tumor necrosis factor (ligand) superfamily member 11 production	biological_process	The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072536	interleukin-23 receptor complex	cellular_component	A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
GO:0072537	fibroblast activation	biological_process	A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0072538	T-helper 17 type immune response	biological_process	An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
GO:0072539	T-helper 17 cell differentiation	biological_process	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
GO:0072540	T-helper 17 cell lineage commitment	biological_process	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
GO:0072541	peroxynitrite reductase activity	molecular_function	Catalysis of the reaction: [protein]-dithiol + ONOO- = [protein]-disulfide + NO2- + H2O.
GO:0072542	protein phosphatase activator activity	molecular_function	Binds to and increases the activity of a protein phosphatase.
GO:0072544	L-DOPA binding	molecular_function	Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.
GO:0072545	tyrosine binding	molecular_function	Binding to 2-amino-3-(4-hydroxyphenyl)propanoic acid.
GO:0072546	EMC complex	cellular_component	A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.
GO:0072547	tricoumaroylspermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.
GO:0072548	dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.
GO:0072549	monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.
GO:0072550	triferuloylspermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.
GO:0072551	diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.
GO:0072552	monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity	molecular_function	Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.
GO:0072553	terminal button organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
GO:0072554	blood vessel lumenization	biological_process	The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.
GO:0072555	17-beta-ketosteroid reductase activity	molecular_function	Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.
GO:0072557	IPAF inflammasome complex	cellular_component	An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
GO:0072558	NLRP1 inflammasome complex	cellular_component	An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.
GO:0072559	NLRP3 inflammasome complex	cellular_component	An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus.
GO:0072560	type B pancreatic cell maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
GO:0072562	blood microparticle	cellular_component	A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
GO:0072563	endothelial microparticle	cellular_component	A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.
GO:0072564	blood microparticle formation	biological_process	The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.
GO:0072565	endothelial microparticle formation	biological_process	The cellular component organization process in which microparticles bud off from an endothelial cell.
GO:0072566	chemokine (C-X-C motif) ligand 1 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072567	chemokine (C-X-C motif) ligand 2 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072570	ADP-D-ribose binding	molecular_function	Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
GO:0072571	mono-ADP-D-ribose binding	molecular_function	Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
GO:0072572	poly-ADP-D-ribose binding	molecular_function	Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
GO:0072573	tolerance induction to lipopolysaccharide	biological_process	Tolerance induction directed at lipopolysaccharide antigens.
GO:0072574	hepatocyte proliferation	biological_process	The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	biological_process	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
GO:0072576	liver morphogenesis	biological_process	The process in which the anatomical structures of the liver are generated and organized.
GO:0072577	endothelial cell apoptotic process	biological_process	Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
GO:0072578	neurotransmitter-gated ion channel clustering	biological_process	The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
GO:0072579	glycine receptor clustering	biological_process	The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.
GO:0072580	bacterial-type EF-P lysine modification	biological_process	The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
GO:0072581	protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine	biological_process	The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
GO:0072583	clathrin-dependent endocytosis	biological_process	An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
GO:0072584	caveolin-mediated endocytosis	biological_process	An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.
GO:0072585	xanthosine nucleotidase activity	molecular_function	Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
GO:0072586	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity	molecular_function	Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0072587	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity	molecular_function	Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0072588	box H/ACA RNP complex	cellular_component	A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.
GO:0072589	box H/ACA scaRNP complex	cellular_component	A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.
GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity	molecular_function	Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
GO:0072591	citrate-L-glutamate ligase activity	molecular_function	Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
GO:0072592	oxygen metabolic process	biological_process	The chemical reactions and pathways involving diatomic oxygen (O2).
GO:0072593	reactive oxygen species metabolic process	biological_process	The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
GO:0072594	establishment of protein localization to organelle	biological_process	The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
GO:0072595	maintenance of protein localization in organelle	biological_process	Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
GO:0072596	establishment of protein localization to chloroplast	biological_process	The directed movement of a protein to a specific location in a chloroplast.
GO:0072597	maintenance of protein location in chloroplast	biological_process	Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.
GO:0072598	protein localization to chloroplast	biological_process	A process in which a protein is transported to, or maintained at, a location in a chloroplast.
GO:0072599	establishment of protein localization to endoplasmic reticulum	biological_process	The directed movement of a protein to a specific location in the endoplasmic reticulum.
GO:0072627	interleukin-28A production	biological_process	The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072629	interleukin-28B production	biological_process	The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072631	interleukin-29 production	biological_process	The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072633	interleukin-30 production	biological_process	The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072635	interleukin-31 production	biological_process	The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072637	interleukin-32 production	biological_process	The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072639	interleukin-33 production	biological_process	The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072645	interferon-delta production	biological_process	The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072647	interferon-epsilon production	biological_process	The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072649	interferon-kappa production	biological_process	The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072651	interferon-tau production	biological_process	The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072653	interferon-omega production	biological_process	The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0072655	establishment of protein localization to mitochondrion	biological_process	The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
GO:0072656	maintenance of protein location in mitochondrion	biological_process	Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
GO:0072657	protein localization to membrane	biological_process	A process in which a protein is transported to, or maintained in, a specific location in a membrane.
GO:0072658	maintenance of protein location in membrane	biological_process	Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
GO:0072659	protein localization to plasma membrane	biological_process	A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
GO:0072660	maintenance of protein location in plasma membrane	biological_process	Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
GO:0072662	protein localization to peroxisome	biological_process	A process in which a protein is transported to, or maintained at, a location in a peroxisome.
GO:0072663	establishment of protein localization to peroxisome	biological_process	The directed movement of a protein to a specific location in a peroxisome.
GO:0072664	maintenance of protein location in peroxisome	biological_process	Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.
GO:0072665	protein localization to vacuole	biological_process	A process in which a protein is transported to, or maintained at, a location in a vacuole.
GO:0072666	establishment of protein localization to vacuole	biological_process	The directed movement of a protein to a specific location in a vacuole.
GO:0072667	maintenance of protein location in vacuole	biological_process	Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.
GO:0072669	tRNA-splicing ligase complex	cellular_component	A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.
GO:0072670	mitochondrial tRNA threonylcarbamoyladenosine modification	biological_process	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).
GO:0072671	mitochondria-associated ubiquitin-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
GO:0072672	neutrophil extravasation	biological_process	The migration of a neutrophil from the blood vessels into the surrounding tissue.
GO:0072673	lamellipodium morphogenesis	biological_process	A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.
GO:0072674	multinuclear osteoclast differentiation	biological_process	The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
GO:0072675	osteoclast fusion	biological_process	The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.
GO:0072676	lymphocyte migration	biological_process	The movement of a lymphocyte within or between different tissues and organs of the body.
GO:0072677	eosinophil migration	biological_process	The movement of an eosinophil within or between different tissues and organs of the body.
GO:0072678	T cell migration	biological_process	The movement of a T cell within or between different tissues and organs of the body.
GO:0072679	thymocyte migration	biological_process	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.
GO:0072680	extracellular matrix-dependent thymocyte migration	biological_process	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.
GO:0072681	fibronectin-dependent thymocyte migration	biological_process	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.
GO:0072682	eosinophil extravasation	biological_process	The migration of an eosinophil from the blood vessels into the surrounding tissue.
GO:0072683	T cell extravasation	biological_process	The migration of a T cell from the blood vessels into the surrounding tissue.
GO:0072685	Mre11 complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.
GO:0072686	mitotic spindle	cellular_component	A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
GO:0072687	meiotic spindle	cellular_component	A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
GO:0072688	SHREC complex localization	biological_process	Any process in which a SHREC complex is transported to, or maintained in, a specific location.
GO:0072689	MCM complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.
GO:0072690	single-celled organism vegetative growth phase	biological_process	A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.
GO:0072695	regulation of DNA recombination at telomere	biological_process	Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.
GO:0072696	positive regulation of DNA recombination at telomere	biological_process	Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.
GO:0072697	protein localization to cell cortex	biological_process	A process in which a protein is transported to, or maintained in, the cell cortex.
GO:0072698	protein localization to microtubule cytoskeleton	biological_process	A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.
GO:0072699	protein localization to cortical microtubule cytoskeleton	biological_process	A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton.
GO:0072700	response to bismuth	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.
GO:0072701	cellular response to bismuth	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.
GO:0072702	response to methyl methanesulfonate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.
GO:0072703	cellular response to methyl methanesulfonate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.
GO:0072704	response to mercaptoethanol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
GO:0072705	cellular response to mercaptoethanol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
GO:0072706	response to sodium dodecyl sulfate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
GO:0072707	cellular response to sodium dodecyl sulfate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
GO:0072708	response to sorbitol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
GO:0072709	cellular response to sorbitol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
GO:0072710	response to hydroxyurea	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
GO:0072711	cellular response to hydroxyurea	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
GO:0072712	response to thiabendazole	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.
GO:0072713	cellular response to thiabendazole	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.
GO:0072714	response to selenite ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
GO:0072715	cellular response to selenite ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
GO:0072716	response to actinomycin D	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
GO:0072717	cellular response to actinomycin D	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
GO:0072718	response to cisplatin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
GO:0072719	cellular response to cisplatin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
GO:0072720	response to dithiothreitol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
GO:0072721	cellular response to dithiothreitol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
GO:0072722	response to amitrole	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.
GO:0072723	cellular response to amitrole	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.
GO:0072724	response to 4-nitroquinoline N-oxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.
GO:0072725	cellular response to 4-nitroquinoline N-oxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.
GO:0072728	response to Gentian violet	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.
GO:0072729	cellular response to Gentian violet	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.
GO:0072730	response to papulacandin B	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.
GO:0072731	cellular response to papulacandin B	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.
GO:0072732	cellular response to calcium ion starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.
GO:0072733	response to staurosporine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
GO:0072734	cellular response to staurosporine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
GO:0072735	response to tert-butyl hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.
GO:0072736	cellular response to tert-butyl hydroperoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.
GO:0072737	response to diamide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
GO:0072738	cellular response to diamide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
GO:0072739	response to anisomycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
GO:0072740	cellular response to anisomycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
GO:0072741	protein localization to cell division site	biological_process	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division.
GO:0072742	SAGA complex localization to transcription regulatory region	biological_process	Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.
GO:0072743	cellular response to erythromycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.
GO:0072744	cellular response to trichodermin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.
GO:0072745	cellular response to antimycin A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.
GO:0072746	cellular response to tetracycline	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.
GO:0072747	cellular response to chloramphenicol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.
GO:0072748	cellular response to tacrolimus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus.
GO:0072749	cellular response to cytochalasin B	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.
GO:0072750	cellular response to leptomycin B	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.
GO:0072751	cellular response to L-thialysine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.
GO:0072752	cellular response to rapamycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
GO:0072753	cellular response to glutathione	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.
GO:0072754	cellular response to purvalanol A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.
GO:0072756	cellular response to paraquat	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
GO:0072757	cellular response to camptothecin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
GO:0072758	response to topoisomerase inhibitor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
GO:0072759	cellular response to topoisomerase inhibitor	biological_process	Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
GO:0072760	cellular response to GW 7647	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.
GO:0072761	cellular response to capsazepine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.
GO:0072762	cellular response to carbendazim	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.
GO:0072763	cellular response to hesperadin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.
GO:0072764	cellular response to reversine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.
GO:0072765	centromere localization	biological_process	A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.
GO:0072766	centromere clustering at the mitotic interphase nuclear envelope	biological_process	The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei.
GO:0075000	response to host osmotic environment	biological_process	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075001	adhesion of symbiont infection structure to host	biological_process	The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075002	adhesion of symbiont germination tube to host	biological_process	The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075003	adhesion of symbiont appressorium to host	biological_process	The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075004	adhesion of symbiont spore to host	biological_process	The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075009	germ tube formation	biological_process	Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075010	regulation of germ tube formation	biological_process	Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075011	positive regulation of germ tube formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075012	negative regulation of germ tube formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075015	formation of infection structure	biological_process	The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075016	appressorium formation	biological_process	The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.
GO:0075017	regulation of appressorium formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont appressorium formation.
GO:0075018	positive regulation of appressorium formation	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation.
GO:0075019	negative regulation of appressorium formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.
GO:0075025	initiation of appressorium formation	biological_process	The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075029	formation of appressorium germ tube hook structure	biological_process	The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation.
GO:0075030	modulation of formation of symbiont germ tube hook structure for appressorium development	biological_process	Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation.
GO:0075031	positive regulation of formation of symbiont germ tube hook structure for appressorium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation.
GO:0075032	negative regulation of formation of symbiont germ tube hook structure for appressorium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation.
GO:0075035	appressorium maturation	biological_process	The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075039	establishment of turgor in appressorium	biological_process	The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075043	melanization of appressorium wall	biological_process	The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium.
GO:0075045	regulation of formation by symbiont of haustorium for nutrient acquisition from host	biological_process	Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075046	positive regulation of formation by symbiont of haustorium for nutrient acquisition from host	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075047	negative regulation of formation by symbiont of haustorium for nutrient acquisition from host	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075053	penetration peg formation	biological_process	The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075054	modulation of penetration peg formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075055	positive regulation of penetration peg formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075069	adhesion of symbiont infection cushion to host	biological_process	The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075070	adhesion of symbiont hyphopodium to host	biological_process	The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075071	symbiont-mediated perturbation of host autophagy	biological_process	Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075109	perturbation of host receptor-mediated signal transduction	biological_process	A process in which a symbiont alters or subverts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075111	symbiont-mediated suppression of host receptor-mediated signal transduction	biological_process	A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075112	perturbation of host transmembrane receptor-mediated signal transduction	biological_process	Any process in which the symbiont alters a transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075114	symbiont-mediated suppression of host transmembrane receptor-mediated signal transduction	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075118	perturbation of host G protein-coupled receptor signal transduction pathway	biological_process	Any process in which the symbiont alters a host G protein-coupled receptor signal transduction pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075120	symbiont-mediated suppression of host G protein-coupled receptor signal transduction	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a G protein-coupled receptor signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075133	perturbation of host calcium or calmodulin-mediated signal transduction	biological_process	A process in which a symbiont alters or subverts a calcium or calmodulin-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075135	symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction	biological_process	A process in which a virus interferes with, inhibits or disrupts a calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075136	response to host	biological_process	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075137	response to host redox environment	biological_process	Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075138	response to host oxygen tension environment	biological_process	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075139	response to host iron concentration	biological_process	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075183	infection cushion formation	biological_process	The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.
GO:0075184	regulation of infection cushion formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont infection cushion formation.
GO:0075185	positive regulation of infection cushion formation	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075186	negative regulation of infection cushion formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075187	hyphopodium formation	biological_process	The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075188	regulation of hyphopodium formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075189	positive regulation of hyphopodium formation	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075190	negative regulation of hyphopodium formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075192	haustorium mother cell formation	biological_process	The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075193	regulation of haustorium mother cell formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075194	positive regulation of haustorium mother cell formation	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075195	negative regulation of haustorium mother cell formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075196	adhesion of symbiont haustorium mother cell to host	biological_process	The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075197	haustorium neck formation	biological_process	The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075198	modulation of symbiont haustorium neck formation for entry into host	biological_process	Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075199	positive regulation of symbiont haustorium neck formation for entry into host	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075201	penetration hypha formation	biological_process	The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075202	regulation of penetration hypha formation	biological_process	Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075203	positive regulation of penetration hypha formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075210	symbiont-mediated suppression of host cAMP-mediated signal transduction	biological_process	A process in which a virus interferes with, inhibits or disrupts a cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075214	spore encystment	biological_process	The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075215	modulation of spore encystment on host	biological_process	Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075216	positive regulation of spore encystment on host	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075217	negative regulation of spore encystment on host	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075218	zoospore encystment on host	biological_process	The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075219	modulation of zoospore encystment on host	biological_process	Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075220	positive regulation of zoospore encystment on host	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075221	negative regulation of zoospore encystment on host	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075222	sporangium germination	biological_process	The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores.
GO:0075223	regulation of sporangium germination	biological_process	Any process that modulates the frequency, rate or extent of sporangium germination.
GO:0075224	positive regulation of sporangium germination	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination.
GO:0075225	negative regulation of sporangium germination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination.
GO:0075226	encysted zoospore germination	biological_process	The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075227	regulation of encysted zoospore germination	biological_process	Any process that modulates the frequency, rate or extent of an encysted zoospore germination.
GO:0075228	positive regulation of encysted zoospore germination	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination.
GO:0075229	negative regulation of encysted zoospore germination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination.
GO:0075239	zoospore formation	biological_process	The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
GO:0075240	regulation of zoospore formation	biological_process	Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
GO:0075241	positive regulation of zoospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
GO:0075242	negative regulation of zoospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
GO:0075243	oospore formation	biological_process	The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.
GO:0075244	regulation of oospore formation	biological_process	Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
GO:0075245	positive regulation of oospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
GO:0075246	negative regulation of oospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
GO:0075247	aeciospore formation	biological_process	The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host.
GO:0075248	regulation of aeciospore formation	biological_process	Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
GO:0075249	positive regulation of aeciospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
GO:0075250	negative regulation of aeciospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
GO:0075251	uredospore formation	biological_process	The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus.
GO:0075252	regulation of uredospore formation	biological_process	Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
GO:0075253	positive regulation of uredospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
GO:0075254	negative regulation of uredospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
GO:0075255	teliospore formation	biological_process	The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
GO:0075256	regulation of teliospore formation	biological_process	Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
GO:0075257	positive regulation of teliospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
GO:0075258	negative regulation of teliospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
GO:0075259	spore-bearing structure development	biological_process	The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.
GO:0075260	regulation of spore-bearing organ development	biological_process	Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
GO:0075261	positive regulation of spore-bearing organ development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
GO:0075262	negative regulation of spore-bearing organ development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
GO:0075263	oogonium development	biological_process	The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.
GO:0075264	regulation of oogonium development	biological_process	Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
GO:0075265	positive regulation of oogonium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
GO:0075266	negative regulation of oogonium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
GO:0075267	aecium development	biological_process	The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium.
GO:0075268	regulation of aecium development	biological_process	Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
GO:0075269	positive regulation of aecium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
GO:0075270	negative regulation of aecium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
GO:0075271	zygosporangium development	biological_process	The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.
GO:0075272	regulation of zygosporangium development	biological_process	Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
GO:0075273	positive regulation of zygosporangium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
GO:0075274	negative regulation of zygosporangium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
GO:0075275	telium development	biological_process	The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.
GO:0075276	regulation of telium development	biological_process	Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
GO:0075277	positive regulation of telium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
GO:0075278	negative regulation of telium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
GO:0075279	uredinium development	biological_process	The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
GO:0075280	regulation of uredinium development	biological_process	Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
GO:0075281	positive regulation of uredinium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
GO:0075282	negative regulation of uredinium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
GO:0075283	sporulation resulting in formation of a multicellular or syncytial spore	biological_process	The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.
GO:0075284	asexual sporulation resulting in formation of a multicellular or syncytial spore	biological_process	The formation of a multicellular or syncytial spore via septations derived from mitosis.
GO:0075285	sexual sporulation resulting in formation of a multicellular or syncytial spore	biological_process	The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
GO:0075286	regulation of sporangiospore formation	biological_process	Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
GO:0075287	positive regulation of sporangiospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
GO:0075288	negative regulation of sporangiospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
GO:0075289	aplanospore formation	biological_process	The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
GO:0075290	regulation of aplanospore formation	biological_process	Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
GO:0075291	positive regulation of aplanospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
GO:0075292	negative regulation of aplanospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
GO:0075293	response to host pH environment	biological_process	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075294	positive regulation by symbiont of entry into host	biological_process	Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.
GO:0075296	positive regulation of ascospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
GO:0075297	negative regulation of ascospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
GO:0075298	regulation of zygospore formation	biological_process	Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
GO:0075299	positive regulation of zygospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
GO:0075300	negative regulation of zygospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
GO:0075302	regulation of basidiospore formation	biological_process	Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.
GO:0075303	positive regulation of basidiospore formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
GO:0075304	negative regulation of basidiospore formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
GO:0075306	regulation of conidium formation	biological_process	Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
GO:0075307	positive regulation of conidium formation	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
GO:0075308	negative regulation of conidium formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
GO:0075310	regulation of sporangium development	biological_process	Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
GO:0075311	positive regulation of sporangium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
GO:0075312	negative regulation of sporangium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
GO:0075313	basidium development	biological_process	The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.
GO:0075314	regulation of basidium development	biological_process	Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.
GO:0075315	positive regulation of basidium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.
GO:0075316	negative regulation of basidium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.
GO:0075317	ascus development	biological_process	The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
GO:0075318	regulation of ascus development	biological_process	Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
GO:0075319	positive regulation of ascus development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
GO:0075320	negative regulation of ascus development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
GO:0075321	oomycete sporangium development	biological_process	The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.
GO:0075322	regulation of oomycete sporangium development	biological_process	Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
GO:0075323	positive regulation of oomycete sporangium development	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
GO:0075324	negative regulation of oomycete sporangium development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
GO:0075325	spore dispersal	biological_process	Any process in which an organism disseminates its spores.
GO:0075328	formation of arbuscule for nutrient acquisition	biological_process	The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075329	regulation of arbuscule formation for nutrient acquisition from host	biological_process	Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075330	positive regulation of arbuscule formation for nutrient acquisition from host	biological_process	Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075331	negative regulation of arbuscule formation for nutrient acquisition from host	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075341	host cell PML body	cellular_component	A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism.
GO:0075342	disruption by symbiont of host cell PML body	biological_process	The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075343	modulation by symbiont of abscisic acid levels in host	biological_process	The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0075502	endosome membrane permeabilization involved in viral entry into host cell	biological_process	Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.
GO:0075503	fusion of virus membrane with host macropinosome membrane	biological_process	Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.
GO:0075504	macropinosomal membrane permeabilization involved in viral entry into host cell	biological_process	Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm.
GO:0075505	entry of intact viral capsid into host nucleus through nuclear pore complex	biological_process	Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC).
GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	biological_process	Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.
GO:0075507	entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome	biological_process	Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm.
GO:0075508	entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm	biological_process	Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm.
GO:0075509	endocytosis involved in viral entry into host cell	biological_process	Any endocytosis that is involved in the uptake of a virus into a host cell.
GO:0075510	macropinocytosis involved in viral entry into host cell	biological_process	Any macropinocytosis that is involved in the uptake of a virus into a host cell.
GO:0075511	macropinosome lysis involved in viral entry into host cell	biological_process	Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm.
GO:0075512	clathrin-dependent endocytosis of virus by host cell	biological_process	Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.
GO:0075513	caveolin-mediated endocytosis of virus by host cell	biological_process	Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus.
GO:0075514	endosome lysis involved in viral entry into host cell	biological_process	Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.
GO:0075519	microtubule-dependent intracellular transport of viral material	biological_process	The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus.
GO:0075520	actin-dependent intracellular transport of virus	biological_process	The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.
GO:0075521	microtubule-dependent intracellular transport of viral material towards nucleus	biological_process	The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.
GO:0075522	IRES-dependent viral translational initiation	biological_process	Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.
GO:0075523	viral translational frameshifting	biological_process	A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.
GO:0075524	ribosomal skipping	biological_process	A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.
GO:0075525	viral translational termination-reinitiation	biological_process	A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.
GO:0075526	cap snatching	biological_process	A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.
GO:0075527	viral RNA editing	biological_process	The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon.
GO:0075528	perturbation by virus of host immune response	biological_process	A process in which a virus effects a change in the host immune response.
GO:0075529	establishment of latency as a circular episome	biological_process	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.
GO:0075530	establishment of latency as a linear episome	biological_process	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.
GO:0075606	transport of viral material towards nucleus	biological_process	The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.
GO:0075713	establishment of integrated proviral latency	biological_process	A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
GO:0075720	establishment of episomal latency	biological_process	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.
GO:0075732	viral penetration into host nucleus	biological_process	The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.
GO:0075733	intracellular transport of virus	biological_process	The directed movement of a virus, or part of a virus, within the host cell.
GO:0080001	mucilage extrusion from seed coat	biological_process	The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.
GO:0080002	UDP-glucose:4-aminobenzoate acylglucosyltransferase activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.
GO:0080003	thalianol metabolic process	biological_process	The chemical reactions and pathways involving the triterpene thalianol.
GO:0080004	thalian-diol desaturase activity	molecular_function	Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15.
GO:0080005	photosystem stoichiometry adjustment	biological_process	Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.
GO:0080006	internode patterning	biological_process	Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.
GO:0080007	S-nitrosoglutathione reductase activity	molecular_function	Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
GO:0080009	mRNA methylation	biological_process	The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
GO:0080011	baruol synthase activity	molecular_function	Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.
GO:0080012	trihydroxyferuloyl spermidine O-methyltransferase activity	molecular_function	Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.
GO:0080013	(E,E)-geranyllinalool synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate.
GO:0080014	thalianol hydroxylase activity	molecular_function	Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.
GO:0080015	sabinene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.
GO:0080016	(-)-E-beta-caryophyllene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.
GO:0080017	alpha-humulene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate.
GO:0080018	anthocyanin 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP.
GO:0080019	alcohol-forming very long-chain fatty acyl-CoA reductase activity	molecular_function	Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA. A very long chain fatty acid (VLCFA) is a fatty acid with an aliphatic tail of 22 or more carbons.
GO:0080020	regulation of coenzyme A biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.
GO:0080021	response to benzoic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.
GO:0080022	primary root development	biological_process	The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.
GO:0080024	indolebutyric acid metabolic process	biological_process	The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	molecular_function	Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.
GO:0080026	response to indolebutyric acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.
GO:0080027	response to herbivore	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.
GO:0080028	nitrile biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.
GO:0080029	cellular response to boron-containing substance levels	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.
GO:0080030	methyl indole-3-acetate esterase activity	molecular_function	Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.
GO:0080031	methyl salicylate esterase activity	molecular_function	Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+.
GO:0080032	methyl jasmonate esterase activity	molecular_function	Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol.
GO:0080033	response to nitrite	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.
GO:0080034	host response to induction by symbiont of tumor, nodule or growth in host	biological_process	Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0080035	2-hydroxy-but-3-enyl glucosinolate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.
GO:0080036	regulation of cytokinin-activated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of cytokinin signaling.
GO:0080037	negative regulation of cytokinin-activated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.
GO:0080038	positive regulation of cytokinin-activated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of cytokinin signaling.
GO:0080040	positive regulation of cellular response to phosphate starvation	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation.
GO:0080041	ADP-ribose pyrophosphohydrolase activity	molecular_function	Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.
GO:0080042	ADP-glucose pyrophosphohydrolase activity	molecular_function	Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.
GO:0080043	quercetin 3-O-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.
GO:0080044	quercetin 7-O-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.
GO:0080045	quercetin 3'-O-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule.
GO:0080046	quercetin 4'-O-glucosyltransferase activity	molecular_function	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.
GO:0080047	GDP-L-galactose phosphorylase activity	molecular_function	Catalysis of the reaction: GDP-beta-L-galactose + phosphate = beta-L-galactose-1-phosphate + GDP.
GO:0080048	GDP-D-glucose phosphorylase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-glucose + phosphate = alpha-D-glucose-1-phosphate + GDP.
GO:0080049	L-gulono-1,4-lactone dehydrogenase activity	molecular_function	Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.
GO:0080050	regulation of seed development	biological_process	Any process that modulates the frequency, rate or extent of seed development.
GO:0080051	cutin transport	biological_process	The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface.
GO:0080052	response to histidine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.
GO:0080053	response to phenylalanine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.
GO:0080054	low-affinity nitrate transmembrane transporter activity	molecular_function	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0080056	petal vascular tissue pattern formation	biological_process	Vascular tissue pattern formation as it occurs in the petal of vascular plants.
GO:0080057	sepal vascular tissue pattern formation	biological_process	Vascular tissue pattern formation as it occurs in the sepal of vascular plants.
GO:0080058	protein deglutathionylation	biological_process	The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.
GO:0080059	flavonol 3-O-arabinosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.
GO:0080060	integument development	biological_process	The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.
GO:0080061	indole-3-acetonitrile nitrilase activity	molecular_function	Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3.
GO:0080062	cytokinin 9-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.
GO:0080064	4,4-dimethyl-9beta,19-cyclopropylsterol oxidation	biological_process	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.
GO:0080065	4-alpha-methyl-delta7-sterol oxidation	biological_process	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.
GO:0080066	3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080067	4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080068	5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080069	7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080070	8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080071	indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate.
GO:0080072	spermidine:sinapoyl CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.
GO:0080073	spermidine:coumaroyl CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.
GO:0080074	spermidine:caffeoyl CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.
GO:0080075	spermidine:feruloyl CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.
GO:0080076	caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule.
GO:0080077	trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.
GO:0080078	tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.
GO:0080079	cellobiose glucosidase activity	molecular_function	Catalysis of the reaction: D-cellobiose + H2O = 2 D-glucose.
GO:0080081	4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity	molecular_function	Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.
GO:0080082	esculin beta-glucosidase activity	molecular_function	Catalysis of the hydrolysis of glucosidic link in esculin.
GO:0080083	beta-gentiobiose beta-glucosidase activity	molecular_function	Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.
GO:0080084	5S rDNA binding	molecular_function	Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.
GO:0080085	signal recognition particle, chloroplast targeting	cellular_component	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast.
GO:0080086	stamen filament development	biological_process	The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen.
GO:0080088	spermidine hydroxycinnamate conjugate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.
GO:0080089	sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity	molecular_function	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.
GO:0080090	regulation of primary metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0080091	regulation of raffinose metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.
GO:0080092	regulation of pollen tube growth	biological_process	Any process that modulates the frequency, rate or extent of pollen tube growth.
GO:0080093	regulation of photorespiration	biological_process	Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved.
GO:0080094	response to trehalose-6-phosphate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.
GO:0080095	phosphatidylethanolamine-sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.
GO:0080096	phosphatidate-sterol O-acyltransferase activity	molecular_function	Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.
GO:0080097	L-tryptophan:pyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine.
GO:0080098	L-tyrosine:pyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.
GO:0080099	L-methionine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.
GO:0080100	L-glutamine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.
GO:0080101	phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.
GO:0080102	3-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate.
GO:0080103	4-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate.
GO:0080104	5-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate.
GO:0080105	6-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.
GO:0080106	7-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.
GO:0080107	8-methylthiopropyl glucosinolate S-oxygenase activity	molecular_function	Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate.
GO:0080108	S-alkylthiohydroximate lyase activity	molecular_function	Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.
GO:0080109	indole-3-acetonitrile nitrile hydratase activity	molecular_function	Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide.
GO:0080110	sporopollenin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.
GO:0080111	DNA demethylation	biological_process	The removal of a methyl group from one or more nucleotides within an DNA molecule.
GO:0080112	seed growth	biological_process	The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo.
GO:0080113	regulation of seed growth	biological_process	Any process that modulates the frequency, rate or extent of growth of the seed of an plant.
GO:0080114	positive regulation of glycine hydroxymethyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
GO:0080115	myosin XI tail binding	molecular_function	Binding to the tail region of a myosin XI heavy chain.
GO:0080116	glucuronoxylan glucuronosyltransferase activity	molecular_function	Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.
GO:0080117	secondary growth	biological_process	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium.
GO:0080118	brassinosteroid sulfotransferase activity	molecular_function	Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.
GO:0080119	ER body organization	biological_process	A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.
GO:0080120	CAAX-box protein maturation	biological_process	A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.
GO:0080121	AMP transport	biological_process	The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0080122	AMP transmembrane transporter activity	molecular_function	Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.
GO:0080123	jasmonate-amino synthetase activity	molecular_function	Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate).
GO:0080124	pheophytinase activity	molecular_function	Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.
GO:0080126	ovary septum development	biological_process	The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).
GO:0080127	fruit septum development	biological_process	The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit.
GO:0080128	anther septum development	biological_process	The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone.
GO:0080129	proteasome core complex assembly	biological_process	The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.
GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.
GO:0080131	hydroxyjasmonate sulfotransferase activity	molecular_function	Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.
GO:0080132	fatty acid alpha-hydroxylase activity	molecular_function	Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
GO:0080133	midchain alkane hydroxylase activity	molecular_function	Catalysis of the conversion of an alkane to a secondary alcohol.
GO:0080134	regulation of response to stress	biological_process	Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0080135	regulation of cellular response to stress	biological_process	Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0080136	priming of cellular response to stress	biological_process	The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress.
GO:0080139	borate efflux transmembrane transporter activity	molecular_function	Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane.
GO:0080140	regulation of jasmonic acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid.
GO:0080141	regulation of jasmonic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid.
GO:0080142	regulation of salicylic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid.
GO:0080143	regulation of amino acid export	biological_process	Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.
GO:0080144	intracellular amino acid homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell.
GO:0080145	intracellular cysteine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of cysteine within a cell.
GO:0080146	L-cysteine desulfhydrase activity	molecular_function	Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.
GO:0080147	root hair cell development	biological_process	The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.
GO:0080148	negative regulation of response to water deprivation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
GO:0080149	sucrose induced translational repression	biological_process	Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level.
GO:0080150	S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity	molecular_function	Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.
GO:0080151	positive regulation of salicylic acid mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.
GO:0080152	regulation of reductive pentose-phosphate cycle	biological_process	Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.
GO:0080153	negative regulation of reductive pentose-phosphate cycle	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.
GO:0080154	regulation of fertilization	biological_process	Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
GO:0080155	regulation of double fertilization forming a zygote and endosperm	biological_process	Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
GO:0080156	mitochondrial mRNA modification	biological_process	The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:0080157	regulation of plant-type cell wall organization or biogenesis	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.
GO:0080159	zygote elongation	biological_process	The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana.
GO:0080160	selenate transport	biological_process	The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0080161	auxin transmembrane transporter activity	molecular_function	Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.
GO:0080162	endoplasmic reticulum to cytosol auxin transport	biological_process	The directed movement of auxins from endoplasmic reticulum to cytosol.
GO:0080163	regulation of protein serine/threonine phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
GO:0080164	regulation of nitric oxide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
GO:0080165	callose deposition in phloem sieve plate	biological_process	Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0080166	stomium development	biological_process	The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.
GO:0080167	response to karrikin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).
GO:0080168	abscisic acid transport	biological_process	The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore.
GO:0080169	cellular response to boron-containing substance deprivation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances.
GO:0080170	hydrogen peroxide transmembrane transport	biological_process	The process in which hydrogen peroxide is transported across a membrane.
GO:0080171	lytic vacuole organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
GO:0080172	petal epidermis patterning	biological_process	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.
GO:0080173	male-female gamete recognition during double fertilization forming a zygote and endosperm	biological_process	The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.
GO:0080175	phragmoplast microtubule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.
GO:0080176	xyloglucan 1,6-alpha-xylosidase activity	molecular_function	Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.
GO:0080177	plastoglobule organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.
GO:0080178	5-carbamoylmethyl uridine residue modification	biological_process	The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA.
GO:0080179	1-methylguanosine metabolic process	biological_process	The chemical reactions and pathways involving 1-methylguanosine.
GO:0080180	2-methylguanosine metabolic process	biological_process	The chemical reactions and pathways involving 2-methylguanosine.
GO:0080181	lateral root branching	biological_process	Any process involved in the formation of branches in lateral roots.
GO:0080182	histone H3-K4 trimethylation	biological_process	The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.
GO:0080183	response to photooxidative stress	biological_process	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0080184	response to phenylpropanoid	biological_process	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.
GO:0080185	effector-mediated induction of plant hypersensitive response by symbiont	biological_process	A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes).
GO:0080186	developmental vegetative growth	biological_process	The increase in size or mass of non-reproductive plant parts.
GO:0080187	floral organ senescence	biological_process	The last stage of flower development during which programmed degradation of macromolecules and nutrient recycling take place.
GO:0080188	gene silencing by RNA-directed DNA methylation	biological_process	A small RNA-based gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism.
GO:0080189	primary growth	biological_process	Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed.
GO:0080190	lateral growth	biological_process	Growth of a plant axis (shoot axis or root) that originates from a lateral meristem.
GO:0080191	secondary thickening	biological_process	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.
GO:0080192	primary thickening	biological_process	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem.
GO:0080193	diffuse secondary thickening	biological_process	Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem.
GO:0085001	formation of stylet for nutrient acquisition	biological_process	The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0085014	dormancy entry of symbiont in host	biological_process	Entry into a dormant state of the symbiont within the host organism.
GO:0085015	dormancy maintenance of symbiont in host	biological_process	Any process in which a dormant state is maintained by the symbiont within the host organism.
GO:0085016	dormancy exit of symbiont in host	biological_process	Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.
GO:0085017	entry into host cell by a symbiont-containing vacuole	biological_process	The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.
GO:0085019	formation of tubovesicular network for nutrient acquisition	biological_process	The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0085020	protein K6-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.
GO:0085026	tubovesicular membrane network	cellular_component	A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains.
GO:0085029	extracellular matrix assembly	biological_process	The aggregation, arrangement and bonding together of the extracellular matrix.
GO:0085030	symbiotic process benefiting host	biological_process	A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism.
GO:0085032	pertubation of host canonical NF-kappaB cascade	biological_process	A process in which a symbiont alters or subverts a canonical NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0085033	induction of host canonical NF-kappaB signal transduction	biological_process	A process that initiates, promotes, or enhances a canonical NF-kappaB-mediated signaling cascade. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0085034	symbiont-mediated suppression of host canonical NF-kappaB cascade	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a canonical  NF-kappaB-mediated signaling cascade in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0085035	haustorium	cellular_component	A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.
GO:0085036	extrahaustorial matrix	cellular_component	The space between the symbiont plasma membrane and the extrahaustorial membrane of the host.
GO:0085037	extrahaustorial membrane	cellular_component	The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane.
GO:0085039	hyphal membrane	cellular_component	A host-derived membrane surrounding the symbiont hypha during infection.
GO:0085041	arbuscule	cellular_component	Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange.
GO:0085042	periarbuscular membrane	cellular_component	A host-derived membrane surrounding the symbiont arbuscule during symbiosis.
GO:0085044	disassembly by symbiont of host cuticle	biological_process	The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0086001	cardiac muscle cell action potential	biological_process	An action potential that occurs in a cardiac muscle cell.
GO:0086002	cardiac muscle cell action potential involved in contraction	biological_process	An action potential that occurs in a cardiac muscle cell and is involved in its contraction.
GO:0086003	cardiac muscle cell contraction	biological_process	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell.
GO:0086004	regulation of cardiac muscle cell contraction	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.
GO:0086005	ventricular cardiac muscle cell action potential	biological_process	An action potential that occurs in a ventricular cardiac muscle cell.
GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086009	membrane repolarization	biological_process	The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
GO:0086010	membrane depolarization during action potential	biological_process	The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086011	membrane repolarization during action potential	biological_process	The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086012	membrane depolarization during cardiac muscle cell action potential	biological_process	The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086013	membrane repolarization during cardiac muscle cell action potential	biological_process	The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086014	atrial cardiac muscle cell action potential	biological_process	An action potential that occurs in an atrial cardiac muscle cell.
GO:0086015	SA node cell action potential	biological_process	An action potential that occurs in a sinoatrial node cardiac muscle cell.
GO:0086016	AV node cell action potential	biological_process	An action potential that occurs in an atrioventricular node cardiac muscle cell.
GO:0086017	Purkinje myocyte action potential	biological_process	An action potential that occurs in a Purkinje myocyte.
GO:0086018	SA node cell to atrial cardiac muscle cell signaling	biological_process	Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.
GO:0086019	cell-cell signaling involved in cardiac conduction	biological_process	Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.
GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling	biological_process	The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0086022	SA node cell-atrial cardiac muscle cell adhesion involved in cell communication	biological_process	The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
GO:0086023	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	biological_process	The series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.
GO:0086024	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate	biological_process	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	biological_process	Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell.
GO:0086027	AV node cell to bundle of His cell signaling	biological_process	Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.
GO:0086028	bundle of His cell to Purkinje myocyte signaling	biological_process	Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.
GO:0086029	Purkinje myocyte to ventricular cardiac muscle cell signaling	biological_process	Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.
GO:0086030	adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation	biological_process	An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation.
GO:0086033	G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	biological_process	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate.
GO:0086036	regulation of cardiac muscle cell membrane potential	biological_process	Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
GO:0086037	P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell.
GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.
GO:0086039	P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential	molecular_function	A calcium-transporting P-type ATPase activity involved in regulation of the plasma membrane potential.
GO:0086040	sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential	molecular_function	Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential.
GO:0086041	voltage-gated potassium channel activity involved in SA node cell action potential depolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion	biological_process	The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.
GO:0086043	bundle of His cell action potential	biological_process	An action potential that occurs in a bundle of His cell.
GO:0086044	atrial cardiac muscle cell to AV node cell communication by electrical coupling	biological_process	The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0086045	membrane depolarization during AV node cell action potential	biological_process	The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086046	membrane depolarization during SA node cell action potential	biological_process	The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086047	membrane depolarization during Purkinje myocyte cell action potential	biological_process	The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086048	membrane depolarization during bundle of His cell action potential	biological_process	The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0086049	membrane repolarization during AV node cell action potential	biological_process	The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086050	membrane repolarization during bundle of His cell action potential	biological_process	The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086051	membrane repolarization during Purkinje myocyte action potential	biological_process	The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086052	membrane repolarization during SA node cell action potential	biological_process	The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0086053	AV node cell to bundle of His cell communication by electrical coupling	biological_process	The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0086054	bundle of His cell to Purkinje myocyte communication by electrical coupling	biological_process	The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0086055	Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling	biological_process	The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086057	voltage-gated calcium channel activity involved in bundle of His cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086058	voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086060	voltage-gated sodium channel activity involved in AV node cell action potential	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086061	voltage-gated sodium channel activity involved in bundle of His cell action potential	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086063	voltage-gated sodium channel activity involved in SA node cell action potential	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	biological_process	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.
GO:0086065	cell communication involved in cardiac conduction	biological_process	Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086066	atrial cardiac muscle cell to AV node cell communication	biological_process	The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086067	AV node cell to bundle of His cell communication	biological_process	The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086068	Purkinje myocyte to ventricular cardiac muscle cell communication	biological_process	The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086069	bundle of His cell to Purkinje myocyte communication	biological_process	The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086070	SA node cell to atrial cardiac muscle cell communication	biological_process	The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0086071	atrial cardiac muscle cell-AV node cell adhesion involved in cell communication	biological_process	The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
GO:0086072	AV node cell-bundle of His cell adhesion involved in cell communication	biological_process	The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	biological_process	The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
GO:0086074	Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication	biological_process	The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086076	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086078	gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086079	gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling	molecular_function	A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	molecular_function	Binding to a protein or protein complex contributing to the adhesion of two different types of cells.
GO:0086081	cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication	molecular_function	Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells.
GO:0086082	cell adhesive protein binding involved in AV node cell-bundle of His cell communication	molecular_function	Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.
GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	molecular_function	Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.
GO:0086084	cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication	molecular_function	Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells.
GO:0086085	cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication	molecular_function	Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells.
GO:0086086	voltage-gated potassium channel activity involved in AV node cell action potential repolarization	molecular_function	Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086087	voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086088	voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086090	voltage-gated potassium channel activity involved in SA node cell action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0086091	regulation of heart rate by cardiac conduction	biological_process	A cardiac conduction process that modulates the frequency or rate of heart contraction.
GO:0086092	regulation of the force of heart contraction by cardiac conduction	biological_process	A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.
GO:0086093	G protein-coupled acetylcholine receptor signaling pathway involved in heart process	biological_process	A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.
GO:0086094	positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction	biological_process	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction.
GO:0086095	positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	biological_process	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.
GO:0086096	adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	biological_process	An adenylate cyclase-inhibiting adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway	biological_process	A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by angiotensin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0086098	angiotensin-activated signaling pathway involved in heart process	biological_process	An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
GO:0086099	phospholipase C-activating angiotensin-activated signaling pathway involved in heart process	biological_process	An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.
GO:0086100	endothelin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0086101	endothelin receptor signaling pathway involved in heart process	biological_process	An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
GO:0086102	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	biological_process	An adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate.
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	biological_process	An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
GO:0089700	protein kinase D signaling	biological_process	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound.
GO:0089701	U2AF complex	cellular_component	A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.
GO:0089702	undecaprenyl-phosphate glucose phosphotransferase activity	molecular_function	Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol.
GO:0089703	L-aspartate transmembrane export from vacuole	biological_process	The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane.
GO:0089704	L-glutamate transmembrane export from vacuole	biological_process	The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.
GO:0089705	protein localization to outer membrane	biological_process	A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.
GO:0089706	L-ornithine transmembrane export from vacuole	biological_process	The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane.
GO:0089707	L-lysine transmembrane export from vacuole	biological_process	The directed movement of L-lysine out of the vacuole, across the vacuolar membrane.
GO:0089708	L-histidine transmembrane export from vacuole	biological_process	The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.
GO:0089709	L-histidine transmembrane transport	biological_process	The directed movement of L-histidine across a membrane.
GO:0089710	endocytic targeting sequence binding	molecular_function	Binding to a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits.
GO:0089713	Cbf1-Met4-Met28 complex	cellular_component	A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.
GO:0089714	UDP-N-acetyl-D-mannosamine dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.
GO:0089715	tRNA m6t6A37 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine at position 37 = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine at position 37.
GO:0089716	Pip2-Oaf1 complex	cellular_component	A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.
GO:0089718	amino acid import across plasma membrane	biological_process	The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.
GO:0089719	RHG protein domain binding	molecular_function	Binding to an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif).
GO:0089720	caspase binding	molecular_function	Binding to a caspase family protein.
GO:0089721	phosphoenolpyruvate transmembrane transporter activity	molecular_function	Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other.
GO:0089722	phosphoenolpyruvate transmembrane transport	biological_process	The directed movement of phosphoenolpytuvate across a membrane.
GO:0090001	replication fork arrest at tRNA locus	biological_process	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.
GO:0090006	regulation of linear element assembly	biological_process	Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.
GO:0090008	hypoblast development	biological_process	The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.
GO:0090009	primitive streak formation	biological_process	The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
GO:0090011	Wnt signaling pathway involved in primitive streak formation	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak.
GO:0090014	leaflet formation	biological_process	The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf.
GO:0090015	positive regulation of leaflet formation by auxin mediated signaling pathway	biological_process	Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.
GO:0090016	regulation of leaflet formation	biological_process	Any process that modulates the frequency, rate or extent of leaflet formation.
GO:0090017	anterior neural plate formation	biological_process	The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
GO:0090018	posterior neural plate formation	biological_process	The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
GO:0090021	positive regulation of posterior neural plate formation by Wnt signaling pathway	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation.
GO:0090022	regulation of neutrophil chemotaxis	biological_process	Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
GO:0090023	positive regulation of neutrophil chemotaxis	biological_process	Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
GO:0090024	negative regulation of neutrophil chemotaxis	biological_process	Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
GO:0090025	regulation of monocyte chemotaxis	biological_process	Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.
GO:0090026	positive regulation of monocyte chemotaxis	biological_process	Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
GO:0090027	negative regulation of monocyte chemotaxis	biological_process	Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.
GO:0090028	positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	biological_process	Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
GO:0090029	negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	biological_process	Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
GO:0090030	regulation of steroid hormone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
GO:0090031	positive regulation of steroid hormone biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
GO:0090032	negative regulation of steroid hormone biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
GO:0090033	positive regulation of filamentous growth	biological_process	Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
GO:0090034	regulation of chaperone-mediated protein complex assembly	biological_process	Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
GO:0090035	positive regulation of chaperone-mediated protein complex assembly	biological_process	Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
GO:0090036	regulation of protein kinase C signaling	biological_process	Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
GO:0090037	positive regulation of protein kinase C signaling	biological_process	Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
GO:0090038	negative regulation of protein kinase C signaling	biological_process	Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
GO:0090042	tubulin deacetylation	biological_process	The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0090043	regulation of tubulin deacetylation	biological_process	Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
GO:0090044	positive regulation of tubulin deacetylation	biological_process	Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
GO:0090045	positive regulation of deacetylase activity	biological_process	Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	biological_process	Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	biological_process	Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
GO:0090052	regulation of pericentric heterochromatin formation	biological_process	Any process that modulates the frequency, rate or extent of heterochromatin formation at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.
GO:0090053	positive regulation of pericentric heterochromatin formation	biological_process	Any process that increases the frequency, rate or extent of pericentric heterochromatin formation.
GO:0090054	regulation of silent mating-type cassette heterochromatin formation	biological_process	Any process that modulates the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.
GO:0090055	positive regulation of silent mating-type cassette heterochromatin formation	biological_process	Any process that increases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.
GO:0090056	regulation of chlorophyll metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll.
GO:0090057	root radial pattern formation	biological_process	The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.
GO:0090058	metaxylem development	biological_process	The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.
GO:0090059	protoxylem development	biological_process	The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem.
GO:0090060	regulation of metaxylem development	biological_process	Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.
GO:0090062	regulation of trehalose metabolic process	biological_process	Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
GO:0090063	positive regulation of microtubule nucleation	biological_process	Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
GO:0090064	activation of microtubule nucleation	biological_process	Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
GO:0090066	regulation of anatomical structure size	biological_process	Any process that modulates the size of an anatomical structure.
GO:0090067	regulation of thalamus size	biological_process	Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.
GO:0090068	positive regulation of cell cycle process	biological_process	Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GO:0090069	regulation of ribosome biogenesis	biological_process	Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GO:0090070	positive regulation of ribosome biogenesis	biological_process	Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GO:0090071	negative regulation of ribosome biogenesis	biological_process	Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GO:0090073	positive regulation of protein homodimerization activity	biological_process	Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
GO:0090074	negative regulation of protein homodimerization activity	biological_process	Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
GO:0090075	relaxation of muscle	biological_process	A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.
GO:0090076	relaxation of skeletal muscle	biological_process	A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
GO:0090077	foam cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0090078	smooth muscle derived foam cell differentiation	biological_process	The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
GO:0090079	translation regulator activity, nucleic acid binding	molecular_function	Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0090083	regulation of inclusion body assembly	biological_process	Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
GO:0090084	negative regulation of inclusion body assembly	biological_process	Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
GO:0090085	regulation of protein deubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
GO:0090086	negative regulation of protein deubiquitination	biological_process	Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
GO:0090087	regulation of peptide transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090088	regulation of oligopeptide transport	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0090089	regulation of dipeptide transport	biological_process	Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090090	negative regulation of canonical Wnt signaling pathway	biological_process	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0090091	positive regulation of extracellular matrix disassembly	biological_process	Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological_process	Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
GO:0090093	regulation of fungal-type cell wall beta-glucan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	biological_process	The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
GO:0090095	regulation of metanephric cap mesenchymal cell proliferation	biological_process	Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	biological_process	Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological_process	Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	biological_process	Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
GO:0090102	cochlea development	biological_process	The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.
GO:0090103	cochlea morphogenesis	biological_process	The process in which the cochlea is generated and organized.
GO:0090104	pancreatic epsilon cell differentiation	biological_process	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.
GO:0090105	pancreatic E cell development	biological_process	The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.
GO:0090106	pancreatic E cell fate commitment	biological_process	The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.
GO:0090107	regulation of high-density lipoprotein particle assembly	biological_process	Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
GO:0090108	positive regulation of high-density lipoprotein particle assembly	biological_process	Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
GO:0090109	regulation of cell-substrate junction assembly	biological_process	Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
GO:0090110	COPII-coated vesicle cargo loading	biological_process	The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
GO:0090111	regulation of COPII vesicle uncoating	biological_process	Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.
GO:0090112	COPII vesicle uncoating	biological_process	The process in which COPII vesicle coat proteins are disassembled, and released.
GO:0090114	COPII-coated vesicle budding	biological_process	The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
GO:0090116	C-5 methylation of cytosine	biological_process	The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.
GO:0090117	endosome to lysosome transport of low-density lipoprotein particle	biological_process	The directed movement of low-density lipoprotein particle from endosomes to lysosomes.
GO:0090118	receptor-mediated endocytosis involved in cholesterol transport	biological_process	A receptor-mediated endocytosis process involved in intracellular cholesterol transport.
GO:0090119	vesicle-mediated cholesterol transport	biological_process	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.
GO:0090120	lysosome to ER cholesterol transport	biological_process	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.
GO:0090121	low-density lipoprotein particle disassembly involved in cholesterol transport	biological_process	The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.
GO:0090122	cholesterol ester hydrolysis involved in cholesterol transport	biological_process	The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
GO:0090123	lysosomal glycocalyx	cellular_component	The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes.
GO:0090124	N-4 methylation of cytosine	biological_process	The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule.
GO:0090125	cell-cell adhesion involved in synapse maturation	biological_process	The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.
GO:0090126	protein-containing complex assembly involved in synapse maturation	biological_process	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.
GO:0090127	positive regulation of synapse maturation by synaptic transmission	biological_process	Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.
GO:0090128	regulation of synapse maturation	biological_process	Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
GO:0090129	positive regulation of synapse maturation	biological_process	Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
GO:0090130	tissue migration	biological_process	The process in which the population of cells that make up a tissue undergo directed movement.
GO:0090131	mesenchyme migration	biological_process	The process in which the population of cells that make up a mesenchyme undergo directed movement.
GO:0090132	epithelium migration	biological_process	The process in which the population of cells that make up an epithelium undergo directed movement.
GO:0090133	mesendoderm migration	biological_process	The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.
GO:0090134	cell migration involved in mesendoderm migration	biological_process	The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.
GO:0090135	actin filament branching	biological_process	The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.
GO:0090136	epithelial cell-cell adhesion	biological_process	The attachment of an epithelial cell to another epithelial cell via adhesion molecules.
GO:0090137	epithelial cell-cell adhesion involved in epithelium migration	biological_process	The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	biological_process	Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
GO:0090139	mitochondrial chromosome packaging	biological_process	A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure.
GO:0090140	regulation of mitochondrial fission	biological_process	Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GO:0090141	positive regulation of mitochondrial fission	biological_process	Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GO:0090143	nucleoid organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.
GO:0090144	mitochondrial nucleoid organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.
GO:0090148	membrane fission	biological_process	A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.
GO:0090149	mitochondrial membrane fission	biological_process	A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.
GO:0090150	establishment of protein localization to membrane	biological_process	The directed movement of a protein to a specific location in a membrane.
GO:0090151	establishment of protein localization to mitochondrial membrane	biological_process	The directed movement of a protein to a specific location in the mitochondrial membrane.
GO:0090152	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	biological_process	The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission.
GO:0090153	regulation of sphingolipid biosynthetic process	biological_process	Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0090154	positive regulation of sphingolipid biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0090155	negative regulation of sphingolipid biosynthetic process	biological_process	Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
GO:0090156	intracellular sphingolipid homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell.
GO:0090158	endoplasmic reticulum membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.
GO:0090159	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization	biological_process	The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization.
GO:0090160	Golgi to lysosome transport	biological_process	The directed movement of substances from the Golgi to lysosomes.
GO:0090161	Golgi ribbon formation	biological_process	The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
GO:0090162	establishment of epithelial cell polarity	biological_process	The specification and formation of anisotropic intracellular organization of an epithelial cell.
GO:0090163	establishment of epithelial cell planar polarity	biological_process	The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.
GO:0090164	asymmetric Golgi ribbon formation	biological_process	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.
GO:0090165	regulation of secretion by asymmetric Golgi ribbon formation	biological_process	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell.
GO:0090166	Golgi disassembly	biological_process	A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
GO:0090167	Golgi distribution to daughter cells	biological_process	Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division.
GO:0090168	Golgi reassembly	biological_process	The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.
GO:0090169	regulation of spindle assembly	biological_process	Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0090170	regulation of Golgi inheritance	biological_process	Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.
GO:0090171	chondrocyte morphogenesis	biological_process	The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
GO:0090172	microtubule cytoskeleton organization involved in homologous chromosome segregation	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis.
GO:0090173	regulation of synaptonemal complex assembly	biological_process	Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.
GO:0090174	organelle membrane fusion	biological_process	The joining of two lipid bilayers to form a single organelle membrane.
GO:0090175	regulation of establishment of planar polarity	biological_process	Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.
GO:0090177	establishment of planar polarity involved in neural tube closure	biological_process	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
GO:0090178	regulation of establishment of planar polarity involved in neural tube closure	biological_process	Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
GO:0090179	planar cell polarity pathway involved in neural tube closure	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
GO:0090180	positive regulation of thiamine biosynthetic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
GO:0090181	regulation of cholesterol metabolic process	biological_process	Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0090182	regulation of secretion of lysosomal enzymes	biological_process	Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
GO:0090183	regulation of kidney development	biological_process	Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0090184	positive regulation of kidney development	biological_process	Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0090185	negative regulation of kidney development	biological_process	Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
GO:0090186	regulation of pancreatic juice secretion	biological_process	Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
GO:0090187	positive regulation of pancreatic juice secretion	biological_process	Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
GO:0090188	negative regulation of pancreatic juice secretion	biological_process	Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	biological_process	Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	biological_process	Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	biological_process	Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
GO:0090192	regulation of glomerulus development	biological_process	Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
GO:0090193	positive regulation of glomerulus development	biological_process	Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
GO:0090194	negative regulation of glomerulus development	biological_process	Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
GO:0090199	regulation of release of cytochrome c from mitochondria	biological_process	Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
GO:0090200	positive regulation of release of cytochrome c from mitochondria	biological_process	Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
GO:0090201	negative regulation of release of cytochrome c from mitochondria	biological_process	Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
GO:0090204	protein localization to nuclear pore	biological_process	A process in which a protein is transported to, or maintained in, a nuclear pore.
GO:0090205	positive regulation of cholesterol metabolic process	biological_process	Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0090206	negative regulation of cholesterol metabolic process	biological_process	Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
GO:0090207	regulation of triglyceride metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
GO:0090208	positive regulation of triglyceride metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
GO:0090209	negative regulation of triglyceride metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
GO:0090210	regulation of establishment of blood-brain barrier	biological_process	Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
GO:0090211	positive regulation of establishment of blood-brain barrier	biological_process	Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
GO:0090212	negative regulation of establishment of blood-brain barrier	biological_process	Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
GO:0090213	regulation of radial pattern formation	biological_process	Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
GO:0090214	spongiotrophoblast layer developmental growth	biological_process	The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.
GO:0090215	regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	biological_process	Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:0090216	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	biological_process	Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:0090217	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	biological_process	Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:0090218	positive regulation of lipid kinase activity	biological_process	Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
GO:0090219	negative regulation of lipid kinase activity	biological_process	Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation	biological_process	The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis.
GO:0090221	mitotic spindle-templated microtubule nucleation	biological_process	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.
GO:0090222	centrosome-templated microtubule nucleation	biological_process	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.
GO:0090223	chromatin-templated microtubule nucleation	biological_process	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.
GO:0090224	regulation of spindle organization	biological_process	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.
GO:0090226	regulation of microtubule nucleation by Ran protein signal transduction	biological_process	The series of molecular signals in which a Ran GTPase relays a signal resulting in the modulation of the rate, frequency or extent of microtubule nucleation.
GO:0090227	regulation of red or far-red light signaling pathway	biological_process	Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GO:0090228	positive regulation of red or far-red light signaling pathway	biological_process	Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GO:0090229	negative regulation of red or far-red light signaling pathway	biological_process	Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
GO:0090230	regulation of centromere complex assembly	biological_process	Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex.
GO:0090231	regulation of spindle checkpoint	biological_process	Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GO:0090232	positive regulation of spindle checkpoint	biological_process	Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GO:0090233	negative regulation of spindle checkpoint	biological_process	Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GO:0090234	regulation of kinetochore assembly	biological_process	Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
GO:0090235	regulation of metaphase plate congression	biological_process	Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.
GO:0090237	regulation of arachidonic acid secretion	biological_process	Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
GO:0090238	positive regulation of arachidonic acid secretion	biological_process	Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
GO:0090239	regulation of histone H4 acetylation	biological_process	Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
GO:0090240	positive regulation of histone H4 acetylation	biological_process	Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
GO:0090241	negative regulation of histone H4 acetylation	biological_process	Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
GO:0090242	retinoic acid receptor signaling pathway involved in somitogenesis	biological_process	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.
GO:0090243	fibroblast growth factor receptor signaling pathway involved in somitogenesis	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.
GO:0090244	Wnt signaling pathway involved in somitogenesis	biological_process	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.
GO:0090245	axis elongation involved in somitogenesis	biological_process	The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.
GO:0090246	convergent extension involved in somitogenesis	biological_process	The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.
GO:0090248	cell migration involved in somitogenic axis elongation	biological_process	Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
GO:0090249	regulation of cell migration involved in somitogenic axis elongation	biological_process	Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
GO:0090250	cell-cell adhesion involved in establishment of planar polarity	biological_process	The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity.
GO:0090251	protein localization involved in establishment of planar polarity	biological_process	Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
GO:0090252	epithelium migration involved in imaginal disc-derived wing morphogenesis	biological_process	The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
GO:0090253	convergent extension involved in imaginal disc-derived wing morphogenesis	biological_process	The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis.
GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis	biological_process	The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.
GO:0090255	cell proliferation involved in imaginal disc-derived wing morphogenesis	biological_process	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.
GO:0090256	regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis	biological_process	Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.
GO:0090257	regulation of muscle system process	biological_process	Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.
GO:0090258	negative regulation of mitochondrial fission	biological_process	Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GO:0090259	regulation of retinal ganglion cell axon guidance	biological_process	Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
GO:0090260	negative regulation of retinal ganglion cell axon guidance	biological_process	Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
GO:0090261	positive regulation of inclusion body assembly	biological_process	Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
GO:0090262	regulation of transcription-coupled nucleotide-excision repair	biological_process	Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
GO:0090263	positive regulation of canonical Wnt signaling pathway	biological_process	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
GO:0090264	regulation of immune complex clearance by monocytes and macrophages	biological_process	Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	biological_process	Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	biological_process	Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	biological_process	Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
GO:0090268	activation of mitotic cell cycle spindle assembly checkpoint	biological_process	Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.
GO:0090269	fibroblast growth factor production	biological_process	The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090270	regulation of fibroblast growth factor production	biological_process	Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090271	positive regulation of fibroblast growth factor production	biological_process	Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090272	negative regulation of fibroblast growth factor production	biological_process	Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090273	regulation of somatostatin secretion	biological_process	Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
GO:0090274	positive regulation of somatostatin secretion	biological_process	Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
GO:0090275	negative regulation of somatostatin secretion	biological_process	Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
GO:0090276	regulation of peptide hormone secretion	biological_process	Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
GO:0090277	positive regulation of peptide hormone secretion	biological_process	Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
GO:0090278	negative regulation of peptide hormone secretion	biological_process	Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
GO:0090279	regulation of calcium ion import	biological_process	Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
GO:0090280	positive regulation of calcium ion import	biological_process	Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
GO:0090281	negative regulation of calcium ion import	biological_process	Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
GO:0090282	positive regulation of transcription involved in G2/M transition of mitotic cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
GO:0090287	regulation of cellular response to growth factor stimulus	biological_process	Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
GO:0090288	negative regulation of cellular response to growth factor stimulus	biological_process	Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
GO:0090289	regulation of osteoclast proliferation	biological_process	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
GO:0090290	positive regulation of osteoclast proliferation	biological_process	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
GO:0090291	negative regulation of osteoclast proliferation	biological_process	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
GO:0090292	nuclear matrix anchoring at nuclear membrane	biological_process	The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.
GO:0090293	nitrogen catabolite regulation of transcription	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
GO:0090294	nitrogen catabolite activation of transcription	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
GO:0090295	nitrogen catabolite repression of transcription	biological_process	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
GO:0090296	regulation of mitochondrial DNA replication	biological_process	Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
GO:0090297	positive regulation of mitochondrial DNA replication	biological_process	Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
GO:0090298	negative regulation of mitochondrial DNA replication	biological_process	Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
GO:0090299	regulation of neural crest formation	biological_process	Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.
GO:0090300	positive regulation of neural crest formation	biological_process	Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
GO:0090301	negative regulation of neural crest formation	biological_process	Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
GO:0090303	positive regulation of wound healing	biological_process	Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
GO:0090304	nucleic acid metabolic process	biological_process	Any cellular metabolic process involving nucleic acids.
GO:0090305	nucleic acid phosphodiester bond hydrolysis	biological_process	The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
GO:0090306	meiotic spindle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
GO:0090307	mitotic spindle assembly	biological_process	Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.
GO:0090308	regulation of DNA methylation-dependent heterochromatin formation	biological_process	Any process that modulates the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation.
GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	biological_process	Any process that increases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation.
GO:0090310	negative regulation of DNA methylation-dependent heterochromatin formation	biological_process	Any process that decreases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation.
GO:0090311	regulation of protein deacetylation	biological_process	Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0090312	positive regulation of protein deacetylation	biological_process	Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:0090313	regulation of protein targeting to membrane	biological_process	Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GO:0090314	positive regulation of protein targeting to membrane	biological_process	Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GO:0090315	negative regulation of protein targeting to membrane	biological_process	Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GO:0090316	positive regulation of intracellular protein transport	biological_process	Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
GO:0090317	negative regulation of intracellular protein transport	biological_process	Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
GO:0090318	regulation of chylomicron remodeling	biological_process	Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0090319	positive regulation of chylomicron remodeling	biological_process	Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
GO:0090320	regulation of chylomicron remnant clearance	biological_process	Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
GO:0090321	positive regulation of chylomicron remnant clearance	biological_process	Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
GO:0090322	regulation of superoxide metabolic process	biological_process	Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
GO:0090323	prostaglandin secretion involved in immune response	biological_process	The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring.
GO:0090324	negative regulation of oxidative phosphorylation	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
GO:0090325	regulation of locomotion involved in locomotory behavior	biological_process	Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GO:0090326	positive regulation of locomotion involved in locomotory behavior	biological_process	Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GO:0090327	negative regulation of locomotion involved in locomotory behavior	biological_process	Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
GO:0090328	regulation of olfactory learning	biological_process	Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
GO:0090329	regulation of DNA-templated DNA replication	biological_process	Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.
GO:0090330	regulation of platelet aggregation	biological_process	Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GO:0090331	negative regulation of platelet aggregation	biological_process	Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GO:0090332	stomatal closure	biological_process	The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
GO:0090333	regulation of stomatal closure	biological_process	Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
GO:0090334	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
GO:0090335	regulation of brown fat cell differentiation	biological_process	Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
GO:0090336	positive regulation of brown fat cell differentiation	biological_process	Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
GO:0090337	regulation of formin-nucleated actin cable assembly	biological_process	Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
GO:0090338	positive regulation of formin-nucleated actin cable assembly	biological_process	Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
GO:0090339	negative regulation of formin-nucleated actin cable assembly	biological_process	Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
GO:0090340	positive regulation of secretion of lysosomal enzymes	biological_process	Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
GO:0090341	negative regulation of secretion of lysosomal enzymes	biological_process	Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
GO:0090345	cellular organohalogen metabolic process	biological_process	The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
GO:0090346	cellular organofluorine metabolic process	biological_process	The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
GO:0090347	regulation of cellular organohalogen metabolic process	biological_process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
GO:0090348	regulation of cellular organofluorine metabolic process	biological_process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
GO:0090349	negative regulation of cellular organohalogen metabolic process	biological_process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
GO:0090350	negative regulation of cellular organofluorine metabolic process	biological_process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
GO:0090351	seedling development	biological_process	The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.
GO:0090352	regulation of nitrate assimilation	biological_process	Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.
GO:0090353	polygalacturonase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of polygalacturonase.
GO:0090354	regulation of auxin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
GO:0090355	positive regulation of auxin metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
GO:0090356	negative regulation of auxin metabolic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
GO:0090357	regulation of tryptophan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0090358	positive regulation of tryptophan metabolic process	biological_process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0090359	negative regulation of abscisic acid biosynthetic process	biological_process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
GO:0090360	platelet-derived growth factor production	biological_process	The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090361	regulation of platelet-derived growth factor production	biological_process	Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090362	positive regulation of platelet-derived growth factor production	biological_process	Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0090363	regulation of proteasome core complex assembly	biological_process	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.
GO:0090364	regulation of proteasome assembly	biological_process	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
GO:0090365	regulation of mRNA modification	biological_process	Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:0090366	positive regulation of mRNA modification	biological_process	Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:0090367	negative regulation of mRNA modification	biological_process	Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:0090368	regulation of ornithine metabolic process	biological_process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
GO:0090369	ornithine carbamoyltransferase inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of ornithine carbamoyltransferase.
GO:0090370	negative regulation of cholesterol efflux	biological_process	Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
GO:0090371	regulation of glycerol transport	biological_process	Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090372	positive regulation of glycerol transport	biological_process	Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090373	negative regulation of glycerol transport	biological_process	Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0090374	oligopeptide export from mitochondrion	biological_process	The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
GO:0090375	negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	biological_process	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
GO:0090376	seed trichome differentiation	biological_process	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.
GO:0090377	seed trichome initiation	biological_process	The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.
GO:0090378	seed trichome elongation	biological_process	The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.
GO:0090379	secondary cell wall biogenesis involved in seed trichome differentiation	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
GO:0090380	seed trichome maturation	biological_process	A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.
GO:0090381	regulation of heart induction	biological_process	Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
GO:0090382	phagosome maturation	biological_process	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.
GO:0090383	phagosome acidification	biological_process	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
GO:0090384	phagosome-lysosome docking	biological_process	The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.
GO:0090385	phagosome-lysosome fusion	biological_process	The creation of a phagolysosome from a phagosome and a lysosome.
GO:0090386	phagosome maturation involved in apoptotic cell clearance	biological_process	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.
GO:0090387	phagolysosome assembly involved in apoptotic cell clearance	biological_process	The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.
GO:0090388	phagosome-lysosome docking involved in apoptotic cell clearance	biological_process	The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere.
GO:0090389	phagosome-lysosome fusion involved in apoptotic cell clearance	biological_process	The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance.
GO:0090390	phagosome acidification involved in apoptotic cell clearance	biological_process	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance.
GO:0090391	granum assembly	biological_process	A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts.
GO:0090392	sepal giant cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.
GO:0090393	sepal giant cell development	biological_process	The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0090394	negative regulation of excitatory postsynaptic potential	biological_process	Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
GO:0090395	plant cell papilla	cellular_component	A cell projection that is a short, rounded projection from a plant epidermal cell.
GO:0090396	leaf papilla	cellular_component	A plant cell papilla that is part of a leaf papilla cell.
GO:0090397	stigma papilla	cellular_component	A plant cell papilla that is part of a stigma papilla cell.
GO:0090398	cellular senescence	biological_process	A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
GO:0090399	replicative senescence	biological_process	A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
GO:0090400	stress-induced premature senescence	biological_process	A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.
GO:0090402	oncogene-induced cell senescence	biological_process	A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.
GO:0090403	oxidative stress-induced premature senescence	biological_process	A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
GO:0090404	pollen tube tip	cellular_component	The region at growing end of the pollen tube cell, where polarized growth occurs.
GO:0090405	unicellular trichome branch	cellular_component	A cell projection part that is a branch of a unicellular trichome.
GO:0090406	pollen tube	cellular_component	A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
GO:0090407	organophosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
GO:0090408	phloem nitrate loading	biological_process	The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
GO:0090409	malonyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate.
GO:0090410	malonate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.
GO:0090411	brassinosteroid binding	molecular_function	Binding to a brassinosteroid.
GO:0090414	molybdate ion export from vacuole	biological_process	The directed movement of molybdate ions out of the vacuole.
GO:0090415	7-hydroxymethyl chlorophyll a reductase activity	molecular_function	Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O.
GO:0090416	nicotinate transmembrane transporter activity	molecular_function	Enables the transfer of nicotinate from one side of a membrane to the other.
GO:0090417	N-methylnicotinate transmembrane transporter activity	molecular_function	Enables the transfer of N-methylnicotinate from one side of a membrane to the other.
GO:0090419	negative regulation of transcription involved in G2/M transition of mitotic cell cycle	biological_process	Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
GO:0090421	embryonic meristem initiation	biological_process	Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.
GO:0090422	thiamine pyrophosphate transmembrane transporter activity	molecular_function	Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.
GO:0090423	phytochelatin-metal complex formation	biological_process	A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.
GO:0090424	phytochelatin-metal-sulfur complex formation	biological_process	A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.
GO:0090425	acinar cell differentiation	biological_process	The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.
GO:0090426	actin filament bundle convergence	biological_process	A process of actin filament bundle distribution that results in the compaction of actin filaments.
GO:0090427	activation of meiosis	biological_process	Any process that starts the inactive process of meiosis.
GO:0090428	perianth development	biological_process	The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.
GO:0090429	detection of endogenous biotic stimulus	biological_process	The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal.
GO:0090430	caffeoyl-CoA: alcohol caffeoyl transferase activity	molecular_function	Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.
GO:0090431	alkyl caffeate ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate.
GO:0090432	myristoyl-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA.
GO:0090433	palmitoyl-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.
GO:0090434	oleoyl-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA.
GO:0090435	protein localization to nuclear envelope	biological_process	A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.
GO:0090436	leaf pavement cell development	biological_process	The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.
GO:0090437	socket cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support.
GO:0090438	camelliol C synthase activity	molecular_function	Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C.
GO:0090439	tetraketide alpha-pyrone synthase activity	molecular_function	Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A .
GO:0090440	abscisic acid transmembrane transporter activity	molecular_function	Enables the transfer of abscisic acid from one side of a membrane to the other.
GO:0090441	trehalose biosynthesis in response to heat stress	biological_process	The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0090442	trehalose catabolism in response to heat stress	biological_process	The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO:0090443	FAR/SIN/STRIPAK complex	cellular_component	A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body.
GO:0090444	regulation of nematode larval development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.
GO:0090445	positive regulation of nematode larval development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.
GO:0090446	negative regulation of nematode larval development, heterochronic	biological_process	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.
GO:0090447	glycerol-3-phosphate 2-O-acyltransferase activity	molecular_function	Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.
GO:0090448	glucosinolate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).
GO:0090449	phloem glucosinolate loading	biological_process	The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
GO:0090451	cotyledon boundary formation	biological_process	The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.
GO:0090452	lithium ion transmembrane transport	biological_process	The directed movement of lithium ions across a membrane.
GO:0090453	aspartate transmembrane import into vacuole	biological_process	The directed movement of aspartate into the vacuole across the vacuolar membrane.
GO:0090454	glutamate transmembrane import into vacuole	biological_process	The directed movement of glutamate into the vacuole across the vacuolar membrane.
GO:0090455	ornithine transmembrane import into vacuole	biological_process	The directed movement of ornithine into the vacuole across the vacuolar membrane.
GO:0090459	intracellular aspartate homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of aspartate within a cell.
GO:0090460	intracellular threonine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of threonine within a cell.
GO:0090461	intracellular glutamate homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell.
GO:0090462	intracellular ornithine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell.
GO:0090463	intracellular lysine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of lysine within a cell.
GO:0090464	intracellular histidine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of histidine within a cell.
GO:0090465	intracellular arginine homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of arginine within a cell.
GO:0090470	shoot organ boundary specification	biological_process	The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.
GO:0090471	9,15,9'-tri-cis-zeta-carotene isomerase activity	molecular_function	Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene.
GO:0090472	dibasic protein processing	biological_process	Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.
GO:0090473	lys-arg specific dibasic protein processing	biological_process	Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein.
GO:0090474	arg-arg specific dibasic protein processing	biological_process	Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.
GO:0090475	lys-lys specific dibasic protein processing	biological_process	Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein.
GO:0090480	purine nucleotide-sugar transmembrane transport	biological_process	The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0090481	pyrimidine nucleotide-sugar transmembrane transport	biological_process	The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
GO:0090482	vitamin transmembrane transporter activity	molecular_function	Enables the transfer of a vitamin from one side of a membrane to the other.
GO:0090483	phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.
GO:0090486	small RNA 2'-O-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA = S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.
GO:0090487	secondary metabolite catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GO:0090488	polo box domain specific binding	molecular_function	Binding to a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases.
GO:0090489	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)	molecular_function	Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.
GO:0090490	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	molecular_function	Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O.
GO:0090491	N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	molecular_function	Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O.
GO:0090492	N,N-Dihydroxy-L-tryptophan decarboxylase activity	molecular_function	Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O.
GO:0090493	catecholamine uptake	biological_process	The directed movement of catecholamine into a cell.
GO:0090494	dopamine uptake	biological_process	The directed movement of dopamine into a cell.
GO:0090495	low-density lipoprotein particle disassembly	biological_process	The disaggregation of a low-density lipoprotein particle into its constituent components.
GO:0090496	mesenchyme migration involved in limb bud formation	biological_process	The migration of mesenchymal tissue that contributes to the formation of a limb bud.
GO:0090497	mesenchymal cell migration	biological_process	The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.
GO:0090498	extrinsic component of Golgi membrane	cellular_component	The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0090499	pimelyl-[acyl-carrier protein] methyl ester esterase activity	molecular_function	Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol.
GO:0090500	endocardial cushion to mesenchymal transition	biological_process	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
GO:0090504	epiboly	biological_process	The expansion of one cell sheet over other cells or yolk.
GO:0090505	epiboly involved in wound healing	biological_process	The expansion of one cell sheet over other cells involved in wound healing.
GO:0090506	axillary shoot meristem initiation	biological_process	A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf.
GO:0090507	phenylethylamine metabolic process involved in synaptic transmission	biological_process	The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission.
GO:0090508	phenylethylamine biosynthetic process involved in synaptic transmission	biological_process	The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission.
GO:0090510	anticlinal cell division	biological_process	A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file.
GO:0090511	periclinal cell division	biological_process	A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file.
GO:0090512	eisosome membrane domain/MCC	cellular_component	A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins.
GO:0090513	L-histidine transmembrane import into vacuole	biological_process	The directed movement of L-histidine into the vacuole across the vacuolar membrane.
GO:0090514	L-tyrosine transmembrane import into vacuole	biological_process	The directed movement of L-tyrosine into the vacuole across the vacuolar membrane.
GO:0090515	L-glutamate transmembrane import into vacuole	biological_process	The directed movement of L-glutamate into the vacuole across the vacuolar membrane.
GO:0090516	L-serine transmembrane import into vacuole	biological_process	The directed movement of L-serine into the vacuole across the vacuolar membrane.
GO:0090517	L-lysine transmembrane import into vacuole	biological_process	The directed movement of L-lysine into the vacuole across the vacuolar membrane.
GO:0090518	L-arginine transmembrane import into vacuole	biological_process	The directed movement of L-arginine into the vacuole across the vacuolar membrane.
GO:0090519	anoxia protection	biological_process	Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia.
GO:0090520	sphingolipid mediated signaling pathway	biological_process	The series of molecular signals mediated by a sphingolipid.
GO:0090521	podocyte cell migration	biological_process	The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.
GO:0090522	vesicle tethering involved in exocytosis	biological_process	The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.
GO:0090523	cytochrome-b5 reductase activity, acting on NADPH	molecular_function	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5).
GO:0090524	cytochrome-b5 reductase activity, acting on NADH	molecular_function	Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5).
GO:0090528	smooth septate junction assembly	biological_process	The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.
GO:0090529	cell septum assembly	biological_process	The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
GO:0090531	L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	biological_process	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose.
GO:0090532	L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	biological_process	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate.
GO:0090533	cation-transporting ATPase complex	cellular_component	Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
GO:0090534	calcium ion-transporting ATPase complex	cellular_component	Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).
GO:0090535	WICH complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.
GO:0090536	NoRC complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.
GO:0090537	CERF complex	cellular_component	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.
GO:0090538	peptide pheromone secretion	biological_process	The regulated release of a peptide pheromone from a cell.
GO:0090539	peptide pheromone export by transmembrane transport	biological_process	The directed movement of a peptide pheromone across a membrane and out of a cell.
GO:0090540	bacterial cellulose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.
GO:0090541	MIT domain binding	molecular_function	Binding to a MIT protein domain. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.
GO:0090542	ELYC domain binding	molecular_function	Binding to a ELYC protein domain. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC.
GO:0090543	Flemming body	cellular_component	A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
GO:0090545	CHD-type complex	cellular_component	A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure.
GO:0090546	chlorophyll fluorescence	biological_process	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light.
GO:0090547	response to low humidity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere.
GO:0090548	response to nitrate starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.
GO:0090549	response to carbon starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source.
GO:0090550	response to molybdenum starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.
GO:0090551	response to manganese starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.
GO:0090552	unicellular trichome apex	cellular_component	A cell projection part that is the apical most portion of a unicellular trichome.
GO:0090553	unicellular trichome tip	cellular_component	A cell projection part that is the apical most portion of a unicellular trichome apex.
GO:0090554	phosphatidylcholine floppase activity	molecular_function	Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0090555	phosphatidylethanolamine flippase activity	molecular_function	Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0090556	phosphatidylserine floppase activity	molecular_function	Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0090557	establishment of endothelial intestinal barrier	biological_process	The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
GO:0090558	plant epidermis development	biological_process	The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.
GO:0090559	regulation of membrane permeability	biological_process	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.
GO:0090560	2-(3-amino-3-carboxypropyl)histidine synthase activity	molecular_function	Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].
GO:0090561	nuclear migration during mitotic telophase	biological_process	The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.
GO:0090562	protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).
GO:0090563	protein-phosphocysteine-sugar phosphotransferase activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0090564	protein-phosphocysteine-glucose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0090565	protein-phosphocysteine-mannitol phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
GO:0090566	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).
GO:0090567	reproductive shoot system development	biological_process	The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.
GO:0090570	RNA polymerase I transcription repressor complex	cellular_component	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.
GO:0090571	RNA polymerase II transcription repressor complex	cellular_component	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter.
GO:0090572	RNA polymerase III transcription repressor complex	cellular_component	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.
GO:0090573	RNA polymerase IV transcription repressor complex	cellular_component	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.
GO:0090574	RNA polymerase V transcription repressor complex	cellular_component	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.
GO:0090575	RNA polymerase II transcription regulator complex	cellular_component	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
GO:0090576	RNA polymerase III transcription regulator complex	cellular_component	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.
GO:0090577	RNA polymerase IV transcription regulator complex	cellular_component	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.
GO:0090578	RNA polymerase V transcription regulator complex	cellular_component	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.
GO:0090580	phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	molecular_function	Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.
GO:0090581	protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).
GO:0090582	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).
GO:0090583	protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in).
GO:0090584	protein-phosphocysteine-galactitol-phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).
GO:0090585	protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).
GO:0090586	protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).
GO:0090587	protein-phosphocysteine-glucosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).
GO:0090588	protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).
GO:0090589	protein-phosphocysteine-trehalose phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).
GO:0090590	protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).
GO:0090591	protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity	molecular_function	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in).
GO:0090592	DNA synthesis involved in DNA replication	biological_process	Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.
GO:0090593	peptidyl-histidine autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.
GO:0090594	inflammatory response to wounding	biological_process	The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.
GO:0090595	acetyl-CoA:L-lysine N6-acetyltransferase	molecular_function	Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H+.
GO:0090596	sensory organ morphogenesis	biological_process	Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0090597	nematode male tail mating organ morphogenesis	biological_process	The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.
GO:0090598	male anatomical structure morphogenesis	biological_process	The processes by which anatomical structures that are only present in the male organism are generated and organized.
GO:0090599	alpha-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.
GO:0090600	alpha-1,3-glucosidase activity	molecular_function	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose.
GO:0090601	enucleation	biological_process	The process in which nucleated precursor cells lose their nucleus.
GO:0090602	sieve element enucleation	biological_process	The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.
GO:0090603	sieve element differentiation	biological_process	The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.
GO:0090604	surface biofilm formation	biological_process	A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0090605	submerged biofilm formation	biological_process	A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0090606	single-species surface biofilm formation	biological_process	A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.
GO:0090609	single-species submerged biofilm formation	biological_process	A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GO:0090610	bundle sheath cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
GO:0090612	cAMP deaminase activity	molecular_function	Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3.
GO:0090613	5'-deoxyadenosine deaminase activity	molecular_function	Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3.
GO:0090614	5'-methylthioadenosine deaminase activity	molecular_function	Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3.
GO:0090615	mitochondrial mRNA processing	biological_process	Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
GO:0090616	mitochondrial mRNA 3'-end processing	biological_process	Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.
GO:0090617	mitochondrial mRNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.
GO:0090618	DNA clamp unloading	biological_process	The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates.
GO:0090619	meiotic spindle pole	cellular_component	Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
GO:0090624	endoribonuclease activity, cleaving miRNA-paired mRNA	molecular_function	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.
GO:0090625	siRNA-mediated gene silencing by mRNA destabilization	biological_process	An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
GO:0090626	plant epidermis morphogenesis	biological_process	The process in which the anatomical structures of the plant epidermis are generated and organized.
GO:0090627	plant epidermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.
GO:0090628	plant epidermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0090629	lagging strand initiation	biological_process	The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.
GO:0090630	activation of GTPase activity	biological_process	Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
GO:0090632	N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.
GO:0090633	keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity	molecular_function	Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.
GO:0090634	microglial cell mediated cytotoxicity	biological_process	The directed killing of a target cell by a microglial cell.
GO:0090635	extracellular core region of desmosome	cellular_component	The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.
GO:0090636	outer dense plaque of desmosome	cellular_component	The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.
GO:0090637	inner dense plaque of desmosome	cellular_component	The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.
GO:0090638	phosphatidylcholine biosynthesis from phosphatidylethanolamine	biological_process	The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations.
GO:0090639	phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol	biological_process	The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.
GO:0090640	phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine	biological_process	The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.
GO:0090641	microsporidian-type endospore	cellular_component	The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.
GO:0090642	microsporidian-type exospore	cellular_component	The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.
GO:0090643	inflorescence phyllotactic patterning	biological_process	The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.
GO:0090644	age-related resistance	biological_process	An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).
GO:0090646	mitochondrial tRNA processing	biological_process	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
GO:0090648	response to environmental enrichment	biological_process	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.
GO:0090649	response to oxygen-glucose deprivation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
GO:0090650	cellular response to oxygen-glucose deprivation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
GO:0090651	apical cytoplasm	cellular_component	The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.
GO:0090652	basolateral cytoplasm	cellular_component	The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.
GO:0090653	apical recycling endosome	cellular_component	Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.
GO:0090654	basolateral recycling endosome	cellular_component	Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.
GO:0090655	double-stranded/single-stranded junction telomeric DNA binding	molecular_function	Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.
GO:0090656	t-circle formation	biological_process	A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).
GO:0090657	telomeric loop disassembly	biological_process	The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
GO:0090658	cone matrix sheath	cellular_component	A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.
GO:0090659	walking behavior	biological_process	The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
GO:0090660	cerebrospinal fluid circulation	biological_process	The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.
GO:0090661	box H/ACA telomerase RNP complex	cellular_component	A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.
GO:0090663	galanin-activated signaling pathway	biological_process	The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.
GO:0090664	response to high population density	biological_process	Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.
GO:0090665	glycoprotein complex	cellular_component	A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.
GO:0090666	scaRNA localization to Cajal body	biological_process	A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
GO:0090667	cell chemotaxis to vascular endothelial growth factor	biological_process	The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).
GO:0090668	endothelial cell chemotaxis to vascular endothelial growth factor	biological_process	The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).
GO:0090669	telomerase RNA stabilization	biological_process	Prevention of degradation of telomerase RNA (TERC) molecules.
GO:0090670	RNA localization to Cajal body	biological_process	A process in which an RNA is transported to, or maintained in, a Cajal body.
GO:0090671	telomerase RNA localization to Cajal body	biological_process	A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.
GO:0090672	telomerase RNA localization	biological_process	Any process in which telomerase RNA is transported to, or maintained in, a specific location.
GO:0090673	endothelial cell-matrix adhesion	biological_process	The binding of an endothelial cell to the extracellular matrix via adhesion molecules.
GO:0090674	endothelial cell-matrix adhesion via fibronectin	biological_process	The binding of an endothelial cell to the extracellular matrix via fibronectin.
GO:0090675	intermicrovillar adhesion	biological_process	The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.
GO:0090676	calcium ion transmembrane transport via low voltage-gated calcium channel	biological_process	A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.
GO:0090677	reversible differentiation	biological_process	A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.
GO:0090678	cell dedifferentiation involved in phenotypic switching	biological_process	A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
GO:0090679	cell differentiation involved in phenotypic switching	biological_process	A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
GO:0090680	viral release via disruption of host outer membrane	biological_process	The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane.
GO:0090681	GPCR taste receptor activity	molecular_function	A G protein-coupled receptor activity that is responsible for the sense of taste.
GO:0090682	GPCR bitter taste receptor activity	molecular_function	A G protein-coupled receptor activity that is responsible for the sense of bitter taste.
GO:0090683	GPCR sweet taste receptor activity	molecular_function	A G protein-coupled receptor activity that is responsible for the sense of sweet taste.
GO:0090684	contact chemoreceptor activity	molecular_function	A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.
GO:0090685	RNA localization to nucleus	biological_process	A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
GO:0090686	glycine betaine-activated nonselective monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.
GO:0090687	activation of meiosis I spindle assembly checkpoint	biological_process	Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.
GO:0090688	cleavage furrow rim	cellular_component	The part of the cleavage furrow closest to the cell surface.
GO:0090689	cleavage furrow leading edge	cellular_component	The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.
GO:0090691	formation of plant organ boundary	biological_process	The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.
GO:0090692	mitochondrial membrane scission site	cellular_component	The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.
GO:0090693	plant organ senescence	biological_process	A plant organ developmental process during which a plant dismantles cellular components to reclaim the cellular building blocks and nutrients that have been deposited in the plant organs during growth.
GO:0090694	Scc2-Scc4 cohesin loading complex	cellular_component	A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.
GO:0090695	Wpl/Pds5 cohesin loading/unloading complex	cellular_component	A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.
GO:0090696	post-embryonic plant organ development	biological_process	Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0090697	post-embryonic plant organ morphogenesis	biological_process	Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0090698	post-embryonic plant morphogenesis	biological_process	The process, occurring after plant embryonic development, by which anatomical structures are generated and organized.
GO:0090700	maintenance of plant organ identity	biological_process	The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0090701	specification of plant organ identity	biological_process	The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
GO:0090704	nicotinate-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.
GO:0090705	trichome papilla	cellular_component	A plant cell papilla that is part of a trichome cell.
GO:0090706	specification of plant organ position	biological_process	The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.
GO:0090707	establishment of plant organ orientation	biological_process	The process that determines the orientation of a plant organ or tissue with reference to an axis.
GO:0090708	specification of plant organ axis polarity	biological_process	The process in which the polarity of a plant organ axis is specified.
GO:0090709	regulation of timing of plant organ formation	biological_process	Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.
GO:0090710	phosphomevalonate decarboxylase activity	molecular_function	Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate.
GO:0090711	FMN hydrolase activity	molecular_function	Catalysis of the reaction: FMN + H2O = riboflavin + phosphate.
GO:0090712	basal pole of outer hair cell	cellular_component	The end of the outer hair cell which receives and transmits neural signals.
GO:0090713	immunological memory process	biological_process	Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.
GO:0090714	innate immunity memory response	biological_process	An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.
GO:0090715	immunological memory formation process	biological_process	Any immunological memory process that can contribute to the formation of immunological memory.
GO:0090716	adaptive immune memory response	biological_process	An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
GO:0090717	adaptive immune memory response involving T cells and B cells	biological_process	An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
GO:0090718	adaptive immune effector response	biological_process	An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response.
GO:0090719	adaptive immune effector response involving T cells and B lineage cells	biological_process	An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.
GO:0090720	primary adaptive immune response	biological_process	An adaptive immune response against an antigen not previously encountered by immune system.
GO:0090721	primary adaptive immune response involving T cells and B cells	biological_process	An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.
GO:0090722	receptor-receptor interaction	molecular_function	The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function.
GO:0090724	central region of growth cone	cellular_component	The center of the migrating motile tip of a growing nerve cell axon or dendrite.
GO:0090725	peripheral region of growth cone	cellular_component	The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.
GO:0090726	cortical dynamic polarity patch	cellular_component	A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.
GO:0090727	positive regulation of brood size	biological_process	Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
GO:0090728	negative regulation of brood size	biological_process	Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
GO:0090729	toxin activity	molecular_function	Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.
GO:0090730	Las1 complex	cellular_component	A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).
GO:0090731	cellular response to very-low-density lipoprotein particle stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.
GO:0090732	cofilin-actin rod	cellular_component	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers.
GO:0090733	tenascin complex	cellular_component	A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R.
GO:0090734	site of DNA damage	cellular_component	A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
GO:0090735	DNA repair complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex.
GO:0090736	MATH domain binding	molecular_function	Binding to a meprin and TRAF homology (MATH) domain.
GO:0090737	telomere maintenance via telomere trimming	biological_process	A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.
GO:0090741	pigment granule membrane	cellular_component	Any membrane that is part of a pigment granule.
GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate	biological_process	The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.
GO:0093002	response to nematicide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.
GO:0095500	acetylcholine receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
GO:0097001	ceramide binding	molecular_function	Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.
GO:0097002	mitochondrial inner boundary membrane	cellular_component	The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.
GO:0097003	adipokinetic hormone receptor activity	molecular_function	Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
GO:0097004	adipokinetic hormone binding	molecular_function	Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
GO:0097005	adipokinetic hormone receptor binding	molecular_function	Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
GO:0097006	regulation of plasma lipoprotein particle levels	biological_process	Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.
GO:0097007	4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity	molecular_function	Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.
GO:0097008	(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity	molecular_function	Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.
GO:0097009	energy homeostasis	biological_process	Any process involved in the balance between food intake (energy input) and energy expenditure.
GO:0097010	eukaryotic translation initiation factor 4F complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
GO:0097012	response to granulocyte macrophage colony-stimulating factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
GO:0097013	phagocytic vesicle lumen	cellular_component	The volume enclosed by the membrane of a phagocytic vesicle.
GO:0097014	ciliary plasm	cellular_component	All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
GO:0097016	L27 domain binding	molecular_function	Binding to a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
GO:0097017	renal protein absorption	biological_process	A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).
GO:0097018	renal albumin absorption	biological_process	A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.
GO:0097019	neurotransmitter receptor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors.
GO:0097020	COPII receptor activity	molecular_function	Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
GO:0097021	lymphocyte migration into lymphoid organs	biological_process	The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
GO:0097022	lymphocyte migration into lymph node	biological_process	The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
GO:0097023	fructose 6-phosphate aldolase activity	molecular_function	Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.
GO:0097025	MPP7-DLG1-LIN7 complex	cellular_component	A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.
GO:0097026	dendritic cell dendrite assembly	biological_process	Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
GO:0097027	ubiquitin-protein transferase activator activity	molecular_function	Binds to and increases the activity of a ubiquitin-protein transferase.
GO:0097028	dendritic cell differentiation	biological_process	The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
GO:0097029	mature conventional dendritic cell differentiation	biological_process	The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
GO:0097030	CENP-A containing nucleosome binding	molecular_function	Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
GO:0097035	regulation of membrane lipid distribution	biological_process	Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.
GO:0097036	regulation of plasma membrane sterol distribution	biological_process	Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.
GO:0097037	heme export	biological_process	The directed movement of heme out of a cell or organelle.
GO:0097038	perinuclear endoplasmic reticulum	cellular_component	The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.
GO:0097039	protein linear polyubiquitination	biological_process	A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
GO:0097040	phthiocerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.
GO:0097041	phenolic phthiocerol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.
GO:0097043	histone H3-K56 acetylation	biological_process	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone.
GO:0097045	phosphatidylserine exposure on blood platelet	biological_process	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.
GO:0097046	replication fork progression beyond termination site	biological_process	Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.
GO:0097047	DNA replication termination region	cellular_component	A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks.
GO:0097048	dendritic cell apoptotic process	biological_process	Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
GO:0097049	motor neuron apoptotic process	biological_process	Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
GO:0097050	type B pancreatic cell apoptotic process	biological_process	Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.
GO:0097051	establishment of protein localization to endoplasmic reticulum membrane	biological_process	The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.
GO:0097052	L-kynurenine metabolic process	biological_process	The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
GO:0097053	L-kynurenine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
GO:0097054	L-glutamate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.
GO:0097055	agmatine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.
GO:0097057	TRAF2-GSTP1 complex	cellular_component	A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses.
GO:0097058	CRLF-CLCF1 complex	cellular_component	A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex.
GO:0097059	CNTFR-CLCF1 complex	cellular_component	A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space.
GO:0097060	synaptic membrane	cellular_component	A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0097061	dendritic spine organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
GO:0097062	dendritic spine maintenance	biological_process	The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
GO:0097063	cadmium ion sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).
GO:0097064	ncRNA export from nucleus	biological_process	The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm.
GO:0097065	anterior head development	biological_process	The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure.
GO:0097066	response to thyroid hormone	biological_process	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
GO:0097067	cellular response to thyroid hormone stimulus	biological_process	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
GO:0097068	response to thyroxine	biological_process	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
GO:0097069	cellular response to thyroxine stimulus	biological_process	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
GO:0097070	ductus arteriosus closure	biological_process	The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.
GO:0097071	interferon regulatory factor complex	cellular_component	A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
GO:0097072	interferon regulatory factor 3 complex	cellular_component	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.
GO:0097073	interferon regulatory factor 5 complex	cellular_component	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5.
GO:0097074	interferon regulatory factor 7 complex	cellular_component	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7.
GO:0097075	interferon regulatory factor 3-interferon regulatory factor 7 complex	cellular_component	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.
GO:0097076	transforming growth factor beta activated kinase 1 complex	cellular_component	A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).
GO:0097077	copper ion sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).
GO:0097078	FAL1-SGD1 complex	cellular_component	A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits.
GO:0097079	selenite:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in).
GO:0097080	plasma membrane selenite transport	biological_process	The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane.
GO:0097081	vascular associated smooth muscle cell fate commitment	biological_process	The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
GO:0097082	vascular associated smooth muscle cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
GO:0097083	vascular associated smooth muscle cell fate determination	biological_process	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
GO:0097084	vascular associated smooth muscle cell development	biological_process	The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
GO:0097085	interferon regulatory factor 3-interferon regulatory factor 5 complex	cellular_component	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5.
GO:0097086	amniotic stem cell differentiation	biological_process	The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone.
GO:0097087	interleukin-17A production	biological_process	The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097088	interleukin-17F production	biological_process	The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097089	methyl-branched fatty acid metabolic process	biological_process	The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
GO:0097090	presynaptic membrane organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
GO:0097091	synaptic vesicle clustering	biological_process	The process that results in grouping synaptic vesicles in presynaptic structures.
GO:0097092	polyacyltrehalose metabolic process	biological_process	The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.
GO:0097093	polyacyltrehalose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.
GO:0097094	craniofacial suture morphogenesis	biological_process	The process in which any suture between cranial and/or facial bones is generated and organized.
GO:0097095	frontonasal suture morphogenesis	biological_process	The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.
GO:0097096	facial suture morphogenesis	biological_process	The process in which any suture between facial bones is generated and organized.
GO:0097097	nasal suture morphogenesis	biological_process	The process in which the nasal suture is generated and organized.
GO:0097098	DNA/RNA hybrid annealing activity	molecular_function	An activity that facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops.
GO:0097099	structural constituent of albumen	molecular_function	The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo.
GO:0097100	supercoiled DNA binding	molecular_function	Binding to supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.
GO:0097101	blood vessel endothelial cell fate specification	biological_process	The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
GO:0097102	endothelial tip cell fate specification	biological_process	The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
GO:0097103	endothelial stalk cell fate specification	biological_process	The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.
GO:0097104	postsynaptic membrane assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
GO:0097105	presynaptic membrane assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
GO:0097106	postsynaptic density organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
GO:0097107	postsynaptic density assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
GO:0097108	hedgehog family protein binding	molecular_function	Binding to a member of the hedgehog protein family, signaling proteins involved in development.
GO:0097109	neuroligin family protein binding	molecular_function	Binding to a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
GO:0097110	scaffold protein binding	molecular_function	Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
GO:0097111	endoplasmic reticulum-Golgi intermediate compartment organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.
GO:0097112	gamma-aminobutyric acid receptor clustering	biological_process	The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.
GO:0097113	AMPA glutamate receptor clustering	biological_process	The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
GO:0097114	NMDA glutamate receptor clustering	biological_process	The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
GO:0097115	neurexin clustering involved in presynaptic membrane assembly	biological_process	The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.
GO:0097116	gephyrin clustering involved in postsynaptic density assembly	biological_process	The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
GO:0097117	guanylate kinase-associated protein clustering	biological_process	The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.
GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	biological_process	The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
GO:0097119	postsynaptic density protein 95 clustering	biological_process	The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
GO:0097120	receptor localization to synapse	biological_process	Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0097121	cyclin A1-CDK1 complex	cellular_component	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097122	cyclin A2-CDK1 complex	cellular_component	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097123	cyclin A1-CDK2 complex	cellular_component	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097124	cyclin A2-CDK2 complex	cellular_component	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097125	cyclin B1-CDK1 complex	cellular_component	A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097126	cyclin B2-CDK1 complex	cellular_component	A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097127	cyclin B3-CDK2 complex	cellular_component	A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097128	cyclin D1-CDK4 complex	cellular_component	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097129	cyclin D2-CDK4 complex	cellular_component	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097130	cyclin D3-CDK4 complex	cellular_component	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097131	cyclin D1-CDK6 complex	cellular_component	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097132	cyclin D2-CDK6 complex	cellular_component	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097133	cyclin D3-CDK6 complex	cellular_component	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097134	cyclin E1-CDK2 complex	cellular_component	A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097135	cyclin E2-CDK2 complex	cellular_component	A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
GO:0097136	Bcl-2 family protein complex	cellular_component	A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.
GO:0097137	BAD-BCL-xl complex	cellular_component	A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097138	BAD-BCL-2 complex	cellular_component	A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097139	BID-BCL-2 complex	cellular_component	A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097140	BIM-BCL-xl complex	cellular_component	A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097141	BIM-BCL-2 complex	cellular_component	A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097142	PUMA-BCL-2 complex	cellular_component	A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097143	PUMA-BCL-xl complex	cellular_component	A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097144	BAX complex	cellular_component	An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097145	BAK complex	cellular_component	An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097146	NOXA-BCL-xl complex	cellular_component	A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097147	NOXA-BCL-2 complex	cellular_component	A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097148	BCL-2 complex	cellular_component	A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.
GO:0097149	centralspindlin complex	cellular_component	A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
GO:0097150	neuronal stem cell population maintenance	biological_process	Any process in by an organism or tissue maintains a population of neuronal stem cells.
GO:0097151	positive regulation of inhibitory postsynaptic potential	biological_process	Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
GO:0097152	mesenchymal cell apoptotic process	biological_process	Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
GO:0097154	GABAergic neuron differentiation	biological_process	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
GO:0097155	fasciculation of sensory neuron axon	biological_process	The collection of sensory neuron axons into a bundle of rods, known as a fascicle.
GO:0097156	fasciculation of motor neuron axon	biological_process	The collection of motor neuron axons into a bundle of rods, known as a fascicle.
GO:0097157	pre-mRNA intronic binding	molecular_function	Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).
GO:0097158	pre-mRNA intronic pyrimidine-rich binding	molecular_function	Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).
GO:0097159	organic cyclic compound binding	molecular_function	Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
GO:0097160	polychlorinated biphenyl binding	molecular_function	Binding to a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings.
GO:0097161	DH domain binding	molecular_function	Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket.
GO:0097162	MADS box domain binding	molecular_function	Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.
GO:0097163	sulfur carrier activity	molecular_function	Covalently binding to sulfur and delivering it to an acceptor molecule.
GO:0097164	ammonium ion metabolic process	biological_process	The chemical reactions and pathways involving the ammonium ion.
GO:0097165	nuclear stress granule	cellular_component	A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
GO:0097166	lens epithelial cell proliferation	biological_process	The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.
GO:0097167	circadian regulation of translation	biological_process	Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.
GO:0097168	mesenchymal stem cell proliferation	biological_process	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
GO:0097169	AIM2 inflammasome complex	cellular_component	An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.
GO:0097170	ADP-L-glycero-beta-D-manno-heptose metabolic process	biological_process	The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
GO:0097171	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
GO:0097172	N-acetylmuramic acid metabolic process	biological_process	The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
GO:0097173	N-acetylmuramic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
GO:0097174	1,6-anhydro-N-acetyl-beta-muramic acid metabolic process	biological_process	The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
GO:0097175	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
GO:0097176	epoxide metabolic process	biological_process	The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.
GO:0097177	mitochondrial ribosome binding	molecular_function	Binding to a mitochondrial ribosome.
GO:0097178	ruffle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.
GO:0097179	protease inhibitor complex	cellular_component	A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.
GO:0097180	serine protease inhibitor complex	cellular_component	A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.
GO:0097181	protein C inhibitor-coagulation factor V complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.
GO:0097182	protein C inhibitor-coagulation factor Xa complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.
GO:0097183	protein C inhibitor-coagulation factor XI complex	cellular_component	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.
GO:0097184	response to azide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
GO:0097185	cellular response to azide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
GO:0097186	amelogenesis	biological_process	The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
GO:0097187	dentinogenesis	biological_process	The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.
GO:0097188	dentin mineralization	biological_process	The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.
GO:0097189	apoptotic body	cellular_component	A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.
GO:0097190	apoptotic signaling pathway	biological_process	The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
GO:0097191	extrinsic apoptotic signaling pathway	biological_process	The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	biological_process	The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
GO:0097193	intrinsic apoptotic signaling pathway	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
GO:0097194	execution phase of apoptosis	biological_process	A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0097195	pilomotor reflex	biological_process	The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.
GO:0097196	Shu complex	cellular_component	A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.
GO:0097197	tetraspanin-enriched microdomain	cellular_component	A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
GO:0097198	histone H3-K36 trimethylation	biological_process	The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.
GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	molecular_function	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	biological_process	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0097202	activation of cysteine-type endopeptidase activity	biological_process	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.
GO:0097203	phagocytic cup lip	cellular_component	The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.
GO:0097204	phagocytic cup base	cellular_component	The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.
GO:0097205	renal filtration	biological_process	A renal system process in which fluid circulating through the body is filtered through a barrier system.
GO:0097206	nephrocyte filtration	biological_process	The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.
GO:0097207	bud dormancy process	biological_process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.
GO:0097208	alveolar lamellar body	cellular_component	A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
GO:0097209	epidermal lamellar body	cellular_component	A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.
GO:0097210	response to gonadotropin-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
GO:0097211	cellular response to gonadotropin-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
GO:0097212	lysosomal membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
GO:0097213	regulation of lysosomal membrane permeability	biological_process	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
GO:0097214	positive regulation of lysosomal membrane permeability	biological_process	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
GO:0097215	negative regulation of lysosomal membrane permeability	biological_process	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
GO:0097216	guanosine tetraphosphate binding	molecular_function	Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
GO:0097217	sieve area	cellular_component	A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.
GO:0097218	sieve plate	cellular_component	A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.
GO:0097219	compound sieve plate	cellular_component	A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.
GO:0097220	simple sieve plate	cellular_component	A sieve plate that contains a single specialized sieve area.
GO:0097221	M/G1 phase-specific MADS box-forkhead transcription factor complex	cellular_component	A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.
GO:0097222	mitochondrial mRNA polyadenylation	biological_process	The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.
GO:0097224	sperm connecting piece	cellular_component	The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.
GO:0097225	sperm midpiece	cellular_component	The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
GO:0097226	sperm mitochondrial sheath	cellular_component	The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
GO:0097227	sperm annulus	cellular_component	The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.
GO:0097228	sperm principal piece	cellular_component	The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
GO:0097229	sperm end piece	cellular_component	The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.
GO:0097230	cell motility in response to potassium ion	biological_process	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.
GO:0097231	cell motility in response to calcium ion	biological_process	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.
GO:0097232	lamellar body membrane	cellular_component	The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
GO:0097233	alveolar lamellar body membrane	cellular_component	The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
GO:0097234	epidermal lamellar body membrane	cellular_component	The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.
GO:0097237	cellular response to toxic substance	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0097238	cellular response to methylglyoxal	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
GO:0097240	chromosome attachment to the nuclear envelope	biological_process	The process in which chromatin is anchored to the nuclear envelope.
GO:0097241	hematopoietic stem cell migration to bone marrow	biological_process	The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
GO:0097242	amyloid-beta clearance	biological_process	The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.
GO:0097243	flavonoid binding	molecular_function	Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.
GO:0097244	flavonol binding	molecular_function	Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.
GO:0097245	flavanol binding	molecular_function	Binding to a flavanol.
GO:0097246	catechin binding	molecular_function	Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.
GO:0097247	epigallocatechin 3-gallate binding	molecular_function	Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.
GO:0097248	maintenance of protein location in cell cortex of cell tip	biological_process	A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.
GO:0097250	mitochondrial respirasome assembly	biological_process	The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.
GO:0097251	leukotriene B4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
GO:0097252	oligodendrocyte apoptotic process	biological_process	Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.
GO:0097253	beta-hydroxybutyrate transmembrane transporter activity	molecular_function	Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.
GO:0097254	renal tubular secretion	biological_process	The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.
GO:0097255	R2TP complex	cellular_component	A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.
GO:0097256	phenyllactate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.
GO:0097257	leukotriene B4 12-hydroxy dehydrogenase activity	molecular_function	Catalysis of the reaction: leukotriene B4 + NADP+ = 12-oxo-leukotriene B4 + NADPH + H+.
GO:0097258	20-hydroxy-leukotriene B4 omega oxidase activity	molecular_function	Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase].
GO:0097259	20-aldehyde-leukotriene B4 20-monooxygenase activity	molecular_function	Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].
GO:0097260	eoxin A4 synthase activity	molecular_function	Catalysis of the reaction: leukotriene A4 = eoxin A4.
GO:0097261	eoxin C4 synthase activity	molecular_function	Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.
GO:0097262	eoxin D4 synthase activity	molecular_function	Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.
GO:0097263	eoxin E4 synthase activity	molecular_function	Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.
GO:0097264	self proteolysis	biological_process	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
GO:0097265	5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity	molecular_function	Catalysis of the reaction: 5-HETE + NADP+ = 5-oxo-ETE + NADPH + H+.
GO:0097266	phenylacetyl-CoA 1,2-epoxidase activity	molecular_function	Catalysis of the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.
GO:0097267	omega-hydroxylase P450 pathway	biological_process	The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
GO:0097268	cytoophidium	cellular_component	A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human.
GO:0097269	all-trans-decaprenyl-diphosphate synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.
GO:0097270	dishabituation	biological_process	The temporary recovery of response to a stimulus when a novel stimulus is added.
GO:0097271	protein localization to bud neck	biological_process	A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
GO:0097272	ammonium homeostasis	biological_process	Any biological process involved in the maintenance of an internal steady state of ammonium.
GO:0097275	intracellular ammonium homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.
GO:0097278	complement-dependent cytotoxicity	biological_process	Cell killing caused by the membrane attack complex formed following complement activation.
GO:0097279	histamine secretion mediated by IgE immunoglobulin	biological_process	Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.
GO:0097280	histamine secretion mediated by immunoglobulin	biological_process	Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.
GO:0097281	immune complex formation	biological_process	The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.
GO:0097282	immunoglobulin-mediated neutralization	biological_process	The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.
GO:0097283	keratinocyte apoptotic process	biological_process	Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
GO:0097284	hepatocyte apoptotic process	biological_process	Any apoptotic process in a hepatocyte, the main structural component of the liver.
GO:0097287	7-cyano-7-deazaguanine metabolic process	biological_process	The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.
GO:0097288	7-cyano-7-deazaguanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.
GO:0097289	alpha-ribazole metabolic process	biological_process	The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
GO:0097290	alpha-ribazole biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
GO:0097291	renal phosphate ion absorption	biological_process	A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
GO:0097292	XMP metabolic process	biological_process	The chemical reactions and pathways involving XMP, xanthosine monophosphate.
GO:0097293	XMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.
GO:0097294	'de novo' XMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.
GO:0097295	morphine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	biological_process	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.
GO:0097298	regulation of nucleus size	biological_process	Any process that modulates the size of the nucleus.
GO:0097300	programmed necrotic cell death	biological_process	A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
GO:0097302	lipoprotein biosynthetic process via diacylglyceryl transfer	biological_process	The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.
GO:0097303	lipoprotein biosynthetic process via N-acyl transfer	biological_process	The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.
GO:0097304	lipoprotein biosynthetic process via signal peptide cleavage	biological_process	The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex.
GO:0097305	response to alcohol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
GO:0097306	cellular response to alcohol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
GO:0097307	response to farnesol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
GO:0097308	cellular response to farnesol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
GO:0097309	cap1 mRNA methylation	biological_process	Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.
GO:0097310	cap2 mRNA methylation	biological_process	Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.
GO:0097311	bacterial biofilm matrix	cellular_component	A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
GO:0097313	bacterial biofilm matrix surface	cellular_component	The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
GO:0097314	apoptosome assembly	biological_process	The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.
GO:0097315	response to N-acetyl-D-glucosamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
GO:0097316	cellular response to N-acetyl-D-glucosamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
GO:0097317	invasive growth in response to biotic stimulus	biological_process	The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.
GO:0097318	invasive growth in response to abiotic stimulus	biological_process	The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.
GO:0097320	plasma membrane tubulation	biological_process	A membrane tubulation process occurring in a plasma membrane.
GO:0097321	cell growth mode switching, filamentous to budding	biological_process	The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.
GO:0097322	7SK snRNA binding	molecular_function	Binding to a 7SK small nuclear RNA (7SK snRNA).
GO:0097323	B cell adhesion	biological_process	The attachment of a B cell to another cell via adhesion molecules.
GO:0097324	melanocyte migration	biological_process	The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
GO:0097325	melanocyte proliferation	biological_process	The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
GO:0097326	melanocyte adhesion	biological_process	The attachment of a melanocyte to another cell via adhesion molecules.
GO:0097327	response to antineoplastic agent	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
GO:0097328	response to carboplatin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.
GO:0097329	response to antimetabolite	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
GO:0097330	response to 5-fluoro-2'-deoxyuridine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
GO:0097331	response to cytarabine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.
GO:0097332	response to antipsychotic drug	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
GO:0097333	response to olanzapine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.
GO:0097334	response to perphenazine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
GO:0097335	response to quetiapine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.
GO:0097336	response to risperidone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.
GO:0097337	response to ziprasidone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
GO:0097338	response to clozapine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
GO:0097339	glycolate transmembrane transport	biological_process	The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).
GO:0097340	inhibition of cysteine-type endopeptidase activity	biological_process	Any process that prevents the activation of an inactive cysteine-type endopeptidase.
GO:0097341	zymogen inhibition	biological_process	Any process that prevents the proteolytic processing of an inactive enzyme to an active form.
GO:0097342	ripoptosome	cellular_component	A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
GO:0097343	ripoptosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
GO:0097344	Rix1 complex	cellular_component	A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.
GO:0097345	mitochondrial outer membrane permeabilization	biological_process	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
GO:0097346	INO80-type complex	cellular_component	A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.
GO:0097347	TAM protein secretion complex	cellular_component	A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.
GO:0097348	host cell endocytic vesicle membrane	cellular_component	The lipid bilayer surrounding a host cell endocytic vesicle.
GO:0097350	neutrophil clearance	biological_process	The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.
GO:0097351	toxin sequestering activity	molecular_function	Binding to a toxin to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0097352	autophagosome maturation	biological_process	Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.
GO:0097353	centrolateral pattern formation	biological_process	The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.
GO:0097354	prenylation	biological_process	The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.
GO:0097355	protein localization to heterochromatin	biological_process	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.
GO:0097356	perinucleolar compartment	cellular_component	The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.
GO:0097358	D-leucyl-tRNA(Leu) deacylase activity	molecular_function	Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu).
GO:0097359	UDP-glucosylation	biological_process	The covalent attachment of a UDP-glucose residue to a substrate molecule.
GO:0097360	chorionic trophoblast cell proliferation	biological_process	The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.
GO:0097361	CIA complex	cellular_component	The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
GO:0097362	MCM8-MCM9 complex	cellular_component	A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.
GO:0097363	protein O-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.
GO:0097364	stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential.
GO:0097365	stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential	molecular_function	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.
GO:0097366	response to bronchodilator	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
GO:0097367	carbohydrate derivative binding	molecular_function	Binding to a carbohydrate derivative.
GO:0097368	establishment of Sertoli cell barrier	biological_process	Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.
GO:0097370	protein O-GlcNAcylation via threonine	biological_process	The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.
GO:0097371	MDM2/MDM4 family protein binding	molecular_function	Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.
GO:0097372	NAD-dependent histone H3K18 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.
GO:0097373	MCM core complex	cellular_component	A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.
GO:0097374	sensory neuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.
GO:0097375	spinal sensory neuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.
GO:0097376	interneuron axon guidance	biological_process	The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.
GO:0097377	spinal cord interneuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.
GO:0097378	dorsal spinal cord interneuron axon guidance	biological_process	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.
GO:0097379	dorsal spinal cord interneuron posterior axon guidance	biological_process	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO:0097380	dorsal spinal cord interneuron anterior axon guidance	biological_process	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
GO:0097381	photoreceptor disc membrane	cellular_component	Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
GO:0097383	dIDP phosphatase activity	molecular_function	Catalysis of the reaction: dIDP + H2O = dIMP + H+ + phosphate.
GO:0097384	cellular lipid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells.
GO:0097385	programmed necrotic cell death in response to starvation	biological_process	A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).
GO:0097386	glial cell projection	cellular_component	A prolongation or process extending from a glial cell.
GO:0097387	capitate projection	cellular_component	Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).
GO:0097388	chemokine (C-C motif) ligand 19 production	biological_process	The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097389	chemokine (C-C motif) ligand 21 production	biological_process	The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097390	chemokine (C-X-C motif) ligand 12 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097391	chemokine (C-X-C motif) ligand 13 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097392	chemokine (C-X-C motif) ligand 16 production	biological_process	The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0097393	telomeric repeat-containing RNA transcription	biological_process	The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.
GO:0097395	response to interleukin-32	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.
GO:0097396	response to interleukin-17	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.
GO:0097397	cellular response to interleukin-32	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.
GO:0097398	cellular response to interleukin-17	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.
GO:0097399	interleukin-32-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-32 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0097400	interleukin-17-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-17 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0097401	synaptic vesicle lumen acidification	biological_process	The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
GO:0097402	neuroblast migration	biological_process	The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
GO:0097403	cellular response to raffinose	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
GO:0097407	Bunina body	cellular_component	Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.
GO:0097408	fibrillary inclusion	cellular_component	Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra.
GO:0097409	glial cytoplasmic inclusion	cellular_component	Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.
GO:0097410	hippocampal interneuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.
GO:0097411	hypoxia-inducible factor-1alpha signaling pathway	biological_process	The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.
GO:0097412	hyaline inclusion	cellular_component	A glass-like, pale intracellular inclusion.
GO:0097413	Lewy body	cellular_component	Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
GO:0097414	classical Lewy body	cellular_component	Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.
GO:0097415	cortical Lewy body	cellular_component	Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.
GO:0097416	Lewy body-like hyaline inclusion	cellular_component	Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.
GO:0097417	nematosome	cellular_component	Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.
GO:0097418	neurofibrillary tangle	cellular_component	Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
GO:0097419	Pick body	cellular_component	Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.
GO:0097420	skein-like inclusion	cellular_component	Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.
GO:0097421	liver regeneration	biological_process	The regrowth of lost or destroyed liver.
GO:0097422	tubular endosome	cellular_component	A network of fine tubules in the vicinity of the Golgi complex and around the centriole.
GO:0097423	mitochondrion-associated adherens complex	cellular_component	An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.
GO:0097424	nucleolus-associated heterochromatin	cellular_component	Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.
GO:0097426	glial filament	cellular_component	An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.
GO:0097427	microtubule bundle	cellular_component	An arrangement of closely apposed microtubules running parallel to each other.
GO:0097428	protein maturation by iron-sulfur cluster transfer	biological_process	The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
GO:0097429	amino acid ligation activity by nonribosomal peptide synthase	molecular_function	Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.
GO:0097430	copper ion import across prospore membrane	biological_process	The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol.
GO:0097431	mitotic spindle pole	cellular_component	Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
GO:0097432	hippocampal pyramidal neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.
GO:0097433	dense body	cellular_component	An electron dense body which may contain granules.
GO:0097434	succinate:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).
GO:0097435	supramolecular fiber organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GO:0097436	entry into dormancy	biological_process	The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
GO:0097437	maintenance of dormancy	biological_process	The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
GO:0097438	exit from dormancy	biological_process	The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
GO:0097439	acquisition of desiccation tolerance	biological_process	The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.
GO:0097440	apical dendrite	cellular_component	A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
GO:0097441	basal dendrite	cellular_component	A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.
GO:0097442	CA3 pyramidal cell dendrite	cellular_component	A dendrite of a hippocampal CA3 pyramidal cell.
GO:0097443	sorting endosome	cellular_component	A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.
GO:0097444	spine apparatus	cellular_component	A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum.
GO:0097445	presynaptic active zone dense projection	cellular_component	Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.
GO:0097446	protein localization to eisosome filament	biological_process	A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.
GO:0097447	dendritic tree	cellular_component	The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.
GO:0097448	spine mat	cellular_component	A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.
GO:0097449	astrocyte projection	cellular_component	A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.
GO:0097450	astrocyte end-foot	cellular_component	Terminal process of astrocyte abutting non-neuronal surfaces in the brain.
GO:0097451	glial limiting end-foot	cellular_component	Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.
GO:0097452	GAIT complex	cellular_component	A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.
GO:0097453	mesaxon	cellular_component	Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.
GO:0097454	Schwann cell microvillus	cellular_component	Small finger-like extension of a Schwann cell that contacts the nodal membrane.
GO:0097455	spiny bracelet of Nageotte	cellular_component	Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.
GO:0097456	terminal loop	cellular_component	Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.
GO:0097457	hippocampal mossy fiber	cellular_component	Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.
GO:0097462	Lewy neurite	cellular_component	Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.
GO:0097463	gemmule	cellular_component	Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.
GO:0097464	thorny excrescence	cellular_component	Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.
GO:0097465	somatic spine	cellular_component	Spine emanating from the cell soma of a neuron.
GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway	biological_process	An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.
GO:0097467	type III terminal bouton	cellular_component	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.
GO:0097468	programmed cell death in response to reactive oxygen species	biological_process	Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
GO:0097470	ribbon synapse	cellular_component	Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.
GO:0097471	mossy fiber rosette	cellular_component	A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.
GO:0097472	cyclin-dependent protein kinase activity	molecular_function	Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0097473	retinal rod cell apoptotic process	biological_process	Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.
GO:0097474	retinal cone cell apoptotic process	biological_process	Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.
GO:0097475	motor neuron migration	biological_process	The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
GO:0097476	spinal cord motor neuron migration	biological_process	The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.
GO:0097477	lateral motor column neuron migration	biological_process	The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.
GO:0097478	leaflet of membrane bilayer	cellular_component	Any of the two layers of lipid molecules that constitute a membrane.
GO:0097479	synaptic vesicle localization	biological_process	Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location.
GO:0097480	establishment of synaptic vesicle localization	biological_process	The directed movement of a synaptic vesicle or vesicles to a specific location.
GO:0097482	muscle cell postsynaptic specialization	cellular_component	A postsynaptic specialization that is part of a neuromuscular junction.
GO:0097484	dendrite extension	biological_process	Long distance growth of a single dendrite involved in cellular development.
GO:0097485	neuron projection guidance	biological_process	The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
GO:0097486	multivesicular body lumen	cellular_component	The volume enclosed by the outermost membrane of a multivesicular body.
GO:0097487	multivesicular body, internal vesicle	cellular_component	A membrane-bounded vesicle wholly contained within a multivesicular body.
GO:0097488	multivesicular body, internal vesicle membrane	cellular_component	The lipid bilayer surrounding a multivesicular body internal vesicle.
GO:0097489	multivesicular body, internal vesicle lumen	cellular_component	The volume enclosed by the membrane of the multivesicular body internal vesicle.
GO:0097490	sympathetic neuron projection extension	biological_process	Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:0097491	sympathetic neuron projection guidance	biological_process	The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
GO:0097492	sympathetic neuron axon guidance	biological_process	The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
GO:0097493	structural molecule activity conferring elasticity	molecular_function	The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.
GO:0097494	regulation of vesicle size	biological_process	Any process that modulates the size of a vesicle.
GO:0097495	H-NS-Hha complex	cellular_component	A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.
GO:0097496	blood vessel lumen ensheathment	biological_process	A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.
GO:0097497	blood vessel endothelial cell delamination	biological_process	The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.
GO:0097498	endothelial tube lumen extension	biological_process	Any endothelial tube morphogenesis process by which the tube is increased in length.
GO:0097499	protein localization to non-motile cilium	biological_process	A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.
GO:0097500	receptor localization to non-motile cilium	biological_process	A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium.
GO:0097501	stress response to metal ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.
GO:0097502	mannosylation	biological_process	The covalent attachment of a mannose residue to a substrate molecule.
GO:0097503	sialylation	biological_process	The covalent attachment of sialic acid to a substrate molecule.
GO:0097504	Gemini of coiled bodies	cellular_component	Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA).
GO:0097505	Rad6-Rad18 complex	cellular_component	A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.
GO:0097506	deaminated base DNA N-glycosylase activity	molecular_function	DNA N-glycosylase activity acting on deaminated bases.
GO:0097507	hypoxanthine DNA N-glycosylase activity	molecular_function	DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).
GO:0097508	xanthine DNA N-glycosylase activity	molecular_function	DNA N-glycosylase activity acting on deaminated guanine (xanthine).
GO:0097509	oxanine DNA N-glycosylase activity	molecular_function	DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.
GO:0097510	base-excision repair, AP site formation via deaminated base removal	biological_process	A base-excision repair, AP site formation process occurring via excision of a deaminated base.
GO:0097511	dendritic cell dendrite	cellular_component	A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
GO:0097512	cardiac myofibril	cellular_component	A cardiac myofibril is a myofibril specific to cardiac muscle cells.
GO:0097513	myosin II filament	cellular_component	A bipolar filament composed of myosin II molecules.
GO:0097514	sexual spore wall	cellular_component	A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.
GO:0097515	asexual spore wall	cellular_component	A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.
GO:0097516	microvillar actin bundle	cellular_component	A parallel bundle of actin filaments at the core of a microvillus.
GO:0097517	contractile actin filament bundle	cellular_component	An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
GO:0097518	parallel actin filament bundle	cellular_component	An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.
GO:0097519	DNA recombinase complex	cellular_component	A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.
GO:0097520	nucleotide-excision repair, preincision complex	cellular_component	A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage.
GO:0097522	protein-DNA ISRE complex	cellular_component	A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.
GO:0097523	transcription ternary complex	cellular_component	A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript.
GO:0097524	sperm plasma membrane	cellular_component	A plasma membrane that is part of a sperm cell.
GO:0097525	spliceosomal snRNP complex	cellular_component	A small ribonucleoprotein complex involved in formation of the spliceosome.
GO:0097526	spliceosomal tri-snRNP complex	cellular_component	A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP.
GO:0097527	necroptotic signaling pathway	biological_process	The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.
GO:0097528	execution phase of necroptosis	biological_process	A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.
GO:0097529	myeloid leukocyte migration	biological_process	The movement of a myeloid leukocyte within or between different tissues and organs of the body.
GO:0097530	granulocyte migration	biological_process	The movement of a granulocyte within or between different tissues and organs of the body.
GO:0097531	mast cell migration	biological_process	The movement of a mast cell within or between different tissues and organs of the body.
GO:0097532	stress response to acid chemical	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GO:0097533	cellular stress response to acid chemical	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GO:0097534	lymphoid lineage cell migration	biological_process	The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.
GO:0097535	lymphoid lineage cell migration into thymus	biological_process	The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.
GO:0097536	thymus epithelium morphogenesis	biological_process	The process in which the thymus epithelium is generated and organized.
GO:0097537	Y-shaped link	cellular_component	A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium.
GO:0097538	ciliary necklace	cellular_component	A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links.
GO:0097539	ciliary transition fiber	cellular_component	A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).
GO:0097540	axonemal central pair	cellular_component	Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.
GO:0097541	axonemal basal plate	cellular_component	Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure.
GO:0097542	ciliary tip	cellular_component	Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
GO:0097543	ciliary inversin compartment	cellular_component	Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.
GO:0097544	ciliary shaft	cellular_component	The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.
GO:0097545	axonemal outer doublet	cellular_component	Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium.
GO:0097546	ciliary base	cellular_component	Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
GO:0097547	synaptic vesicle protein transport vesicle	cellular_component	A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.
GO:0097548	seed abscission	biological_process	The controlled shedding of a seed.
GO:0097550	transcription preinitiation complex	cellular_component	A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
GO:0097551	mitochondrial double-strand break repair	biological_process	The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
GO:0097552	mitochondrial double-strand break repair via homologous recombination	biological_process	The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.
GO:0097553	calcium ion transmembrane import into cytosol	biological_process	A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.
GO:0097554	left anterior flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.
GO:0097555	right anterior flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.
GO:0097556	left posteriolateral flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.
GO:0097557	right posteriolateral flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.
GO:0097558	left ventral flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
GO:0097559	right ventral flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
GO:0097560	left caudal flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
GO:0097561	right caudal flagellum	cellular_component	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
GO:0097562	left lateral basal body pair	cellular_component	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
GO:0097563	left middle basal body pair	cellular_component	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
GO:0097564	right lateral basal body pair	cellular_component	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
GO:0097565	right middle basal body pair	cellular_component	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
GO:0097566	left tetrad	cellular_component	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).
GO:0097567	right tetrad	cellular_component	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).
GO:0097568	median body	cellular_component	A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.
GO:0097569	lateral shield	cellular_component	Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.
GO:0097570	cyst wall	cellular_component	The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.
GO:0097571	left nucleus	cellular_component	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.
GO:0097572	right nucleus	cellular_component	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.
GO:0097574	lateral part of cell	cellular_component	The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.
GO:0097575	lateral cell cortex	cellular_component	The region directly beneath the plasma membrane of the lateral portion of the cell.
GO:0097576	vacuole fusion	biological_process	Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
GO:0097577	sequestering of iron ion	biological_process	The process of binding or confining iron ions such that they are separated from other components of a biological system.
GO:0097578	sequestering of copper ion	biological_process	The process of binding or confining copper ions such that they are separated from other components of a biological system.
GO:0097579	extracellular sequestering of copper ion	biological_process	The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.
GO:0097580	intracellular sequestering of copper ion	biological_process	The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.
GO:0097581	lamellipodium organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
GO:0097582	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	cellular_component	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.
GO:0097583	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex	cellular_component	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.
GO:0097584	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	cellular_component	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.
GO:0097585	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex	cellular_component	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.
GO:0097586	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex	cellular_component	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.
GO:0097587	MutLgamma complex	cellular_component	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.
GO:0097588	archaeal or bacterial-type flagellum-dependent cell motility	biological_process	Cell motility due to movement of bacterial- or archaeal-type flagella.
GO:0097589	archaeal-type flagellum	cellular_component	A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function.
GO:0097590	archaeal-type flagellum-dependent cell motility	biological_process	Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.
GO:0097591	ventral disc lateral crest	cellular_component	Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.
GO:0097592	ventral disc overlap zone	cellular_component	A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).
GO:0097593	ventral disc microtubule array	cellular_component	A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.
GO:0097594	ventral disc dorsal microribbon	cellular_component	Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons.
GO:0097595	ventral disc crossbridge	cellular_component	Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet.
GO:0097596	ventral disc supernumerary microtubule array	cellular_component	A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage).
GO:0097597	ventral disc	cellular_component	Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence.
GO:0097598	sperm cytoplasmic droplet	cellular_component	A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.
GO:0097599	xylanase activity	molecular_function	Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues.
GO:0097600	exoxylanase activity	molecular_function	A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.
GO:0097601	retina blood vessel maintenance	biological_process	A retina homeostatic process preventing the degeneration of a retina blood vessel.
GO:0097602	cullin family protein binding	molecular_function	Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).
GO:0097603	temperature-gated ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).
GO:0097604	temperature-gated cation channel activity	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).
GO:0097608	transverse flagellum	cellular_component	A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum.
GO:0097609	longitudinal flagellum	cellular_component	A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.
GO:0097610	cell surface furrow	cellular_component	A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates.
GO:0097611	dinoflagellate cingulum	cellular_component	A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it.
GO:0097612	dinoflagellate sulcus	cellular_component	A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell.
GO:0097613	dinoflagellate epicone	cellular_component	The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum.
GO:0097614	dinoflagellate hypocone	cellular_component	The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum.
GO:0097615	modulation by host of symbiont type IV pilus-dependent motility	biological_process	The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0097616	positive regulation by host of symbiont type IV pilus-dependent motility	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0097618	dinoflagellate sulcal notch	cellular_component	A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed.
GO:0097619	PTEX complex	cellular_component	A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components.
GO:0097620	(R)-mandelate dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor.
GO:0097621	monoamine oxidase activity	molecular_function	Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.
GO:0097622	cytoplasmic translational elongation through polyproline stretches	biological_process	The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.
GO:0097623	potassium ion export across plasma membrane	biological_process	The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0097624	UDP-galactose transmembrane import into Golgi lumen	biological_process	The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane.
GO:0097625	low-affinity basic amino acid transmembrane transporter activity	molecular_function	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0097626	low-affinity L-arginine transmembrane transporter activity	molecular_function	Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
GO:0097627	high-affinity L-ornithine transmembrane transporter activity	molecular_function	Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0097628	distal tip cell migration	biological_process	The orderly movement of a distal tip cell.
GO:0097629	extrinsic component of omegasome membrane	cellular_component	The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0097632	extrinsic component of phagophore assembly site membrane	cellular_component	The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0097638	L-arginine import across plasma membrane	biological_process	The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0097639	L-lysine import across plasma membrane	biological_process	The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0097640	L-ornithine import across plasma membrane	biological_process	The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0097641	alpha-ketoglutarate-dependent xanthine dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate.
GO:0097642	calcitonin family receptor activity	molecular_function	Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.
GO:0097643	amylin receptor activity	molecular_function	Combining with amylin to initiate a change in cell activity.
GO:0097644	calcitonin family binding	molecular_function	Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).
GO:0097645	amylin binding	molecular_function	Binding to amylin.
GO:0097646	calcitonin family receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0097647	amylin receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by amylin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
GO:0097648	G protein-coupled receptor complex	cellular_component	A protein complex that contains G protein-coupled receptors.
GO:0097649	A axonemal microtubule	cellular_component	A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.
GO:0097650	B axonemal microtubule	cellular_component	An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.
GO:0097651	phosphatidylinositol 3-kinase complex, class I	cellular_component	A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.
GO:0097652	phosphatidylinositol 3-kinase complex, class II	cellular_component	A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.
GO:0097653	unencapsulated part of cell	cellular_component	The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.
GO:0097654	platelet SNARE complex	cellular_component	A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.
GO:0097655	serpin family protein binding	molecular_function	Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.
GO:0097656	cell-cell self recognition	biological_process	A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.
GO:0097657	3',5'-nucleotide bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.
GO:0097658	Asi complex	cellular_component	A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.
GO:0097660	SCF-Cdc4 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.
GO:0097661	SCF-Ctf13 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.
GO:0097662	SCF-Das1 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.
GO:0097663	SCF-Dia2/Pof3 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).
GO:0097664	SCF-Grr1/Pof2 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).
GO:0097665	SCF-Mdm30 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.
GO:0097666	SCF-Met30/Pof1 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).
GO:0097667	SCF-Rcy1/Pof6 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).
GO:0097668	SCF-Saf1/Pof9 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).
GO:0097669	SCF-Skp2 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.
GO:0097670	SCF-Ufo1/Pof10 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).
GO:0097671	SCF-YDR131C ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.
GO:0097672	SCF-Pof5 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).
GO:0097673	SCF-Ucc1 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.
GO:0097674	SCF-YLR352W ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.
GO:0097675	SCF-Hrt3/Pof7 ubiquitin ligase complex	cellular_component	An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).
GO:0097676	histone H3-K36 dimethylation	biological_process	The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.
GO:0097677	STAT family protein binding	molecular_function	Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.
GO:0097678	SOCS family protein binding	molecular_function	Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.
GO:0097680	double-strand break repair via classical nonhomologous end joining	biological_process	An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).
GO:0097681	double-strand break repair via alternative nonhomologous end joining	biological_process	An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.
GO:0097682	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity	molecular_function	Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.
GO:0097683	dinoflagellate apex	cellular_component	The anterior most point of a dinoflagellate epicone.
GO:0097684	dinoflagellate antapex	cellular_component	The anterior most point of a dinoflagellate hypocone.
GO:0097685	dinoflagellate apical groove	cellular_component	A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.
GO:0097686	dinoflagellate apical horn	cellular_component	A horn-shaped dinoflagellate apex found in thecate species.
GO:0097687	dinoflagellate antapical horn	cellular_component	A horn-shaped dinoflagellate antapex found in thecate species.
GO:0097688	glutamate receptor clustering	biological_process	The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.
GO:0097690	iron ion transmembrane transporter inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.
GO:0097691	bacterial extracellular vesicle	cellular_component	Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.
GO:0097692	histone H3-K4 monomethylation	biological_process	The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone.
GO:0097693	ocelloid	cellular_component	Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.
GO:0097694	establishment of RNA localization to telomere	biological_process	The directed movement of RNA to a specific location in the telomeric region of a chromosome.
GO:0097695	establishment of protein-containing complex localization to telomere	biological_process	The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.
GO:0097696	receptor signaling pathway via STAT	biological_process	An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
GO:0097697	tRNA 5-carboxymethoxyuridine methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule.
GO:0097698	telomere maintenance via base-excision repair	biological_process	A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.
GO:0097699	vascular endothelial cell response to fluid shear stress	biological_process	Any response to fluid shear stress in a vascular endothelial cell.
GO:0097700	vascular endothelial cell response to laminar fluid shear stress	biological_process	Any response to laminar fluid shear stress in a vascular endothelial cell.
GO:0097701	response to pulsatile fluid shear stress	biological_process	Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.
GO:0097702	response to oscillatory fluid shear stress	biological_process	Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.
GO:0097703	cellular response to pulsatile fluid shear stress	biological_process	Any response to pulsatile fluid shear stress that occurs at the level of a cell.
GO:0097704	cellular response to oscillatory fluid shear stress	biological_process	Any response to oscillatory fluid shear stress that occurs at the level of a cell.
GO:0097705	vascular endothelial cell response to pulsatile fluid shear stress	biological_process	Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.
GO:0097706	vascular endothelial cell response to oscillatory fluid shear stress	biological_process	Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.
GO:0097707	ferroptosis	biological_process	A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.
GO:0097708	intracellular vesicle	cellular_component	Any vesicle that is part of the intracellular region.
GO:0097709	connective tissue replacement	biological_process	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.
GO:0097710	viral terminase, small subunit	cellular_component	The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.
GO:0097711	ciliary basal body-plasma membrane docking	biological_process	The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
GO:0097712	vesicle targeting, trans-Golgi to periciliary membrane compartment	biological_process	The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
GO:0097713	dolichol-phosphate-mannose synthase regulator activity	molecular_function	Binds to and modulates the activity of dolichol-phosphate-mannose synthase.
GO:0097714	response to viscosity	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
GO:0097715	cellular response to viscosity	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
GO:0097716	copper ion transport across blood-brain barrier	biological_process	The directed movement of copper (Cu) ions passing through the blood-brain barrier.
GO:0097717	copper ion transport across blood-cerebrospinal fluid barrier	biological_process	The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.
GO:0097718	disordered domain specific binding	molecular_function	Binding to a disordered domain of a protein.
GO:0097719	neural tissue regeneration	biological_process	The regrowth of neural tissue following its loss or destruction.
GO:0097720	calcineurin-mediated signaling	biological_process	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression.
GO:0097721	ciliary vesicle	cellular_component	A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.
GO:0097722	sperm motility	biological_process	Any process involved in the controlled movement of a sperm cell.
GO:0097723	amoeboid sperm motility	biological_process	Any process involved in the controlled movement of an amoeboid sperm cell.
GO:0097726	LEM domain binding	molecular_function	Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).
GO:0097727	blepharoplast	cellular_component	An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.
GO:0097728	9+0 motile cilium	cellular_component	A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).
GO:0097729	9+2 motile cilium	cellular_component	A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).
GO:0097730	non-motile cilium	cellular_component	A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
GO:0097731	9+0 non-motile cilium	cellular_component	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).
GO:0097732	9+2 non-motile cilium	cellular_component	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).
GO:0097733	photoreceptor cell cilium	cellular_component	A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.
GO:0097734	extracellular exosome biogenesis	biological_process	The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
GO:0097735	DIM/DIP cell wall layer	cellular_component	A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.
GO:0097736	aerial mycelium formation	biological_process	The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.
GO:0097737	acquisition of mycelium reproductive competence	biological_process	A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.
GO:0097738	substrate mycelium formation	biological_process	The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.
GO:0097739	negative regulation of ferrichrome biosynthetic process in response to iron	biological_process	Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.
GO:0097740	paraflagellar rod	cellular_component	A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signaling and metabolism, and in calcium signaling.
GO:0097741	mastigoneme	cellular_component	A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.
GO:0097742	de novo centriole assembly	biological_process	Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.
GO:0097743	de novo centriole assembly via blepharoplast	biological_process	A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.
GO:0097744	renal urate salt excretion	biological_process	The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
GO:0097745	mitochondrial tRNA 5'-end processing	biological_process	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
GO:0097746	blood vessel diameter maintenance	biological_process	Any process that modulates the diameter of blood vessels.
GO:0097747	RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.
GO:0097748	3'-5' RNA polymerase activity	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.
GO:0097749	membrane tubulation	biological_process	A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).
GO:0097750	endosome membrane tubulation	biological_process	A membrane tubulation process occurring in an endosome membrane.
GO:0097751	spore-bearing structure formation	biological_process	The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.
GO:0097752	regulation of DNA stability	biological_process	Any process that modulates the stability of DNA.
GO:0097753	membrane bending	biological_process	A membrane organization process resulting in the bending of a membrane.
GO:0097754	clathrin-mediated membrane bending	biological_process	A membrane bending process mediated by clathrin.
GO:0098001	receptor-mediated bacteriophage reversible attachment to host cell	biological_process	Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.
GO:0098002	receptor-mediated bacteriophage irreversible attachment to host cell	biological_process	The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.
GO:0098003	viral tail assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a virus tail.
GO:0098004	virus tail fiber assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.
GO:0098005	viral head-tail joining	biological_process	Process by which virus heads and tails are attached to each other.
GO:0098006	viral DNA genome packaging, headful	biological_process	The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.
GO:0098009	viral terminase, large subunit	cellular_component	The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.
GO:0098015	virus tail	cellular_component	Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.
GO:0098017	viral capsid, major subunit	cellular_component	The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.
GO:0098018	viral capsid, minor subunit	cellular_component	The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.
GO:0098021	viral capsid, decoration	cellular_component	Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential.
GO:0098022	viral capsid, fiber	cellular_component	A type of capsid decoration composed of fiber structures.
GO:0098023	virus tail, tip	cellular_component	The basal end of the virus tail, which is used by the virus to attach to the host cell.
GO:0098024	virus tail, fiber	cellular_component	The fibrous region of the virus tail used to scan, recognize and attach to the host cell.
GO:0098025	virus tail, baseplate	cellular_component	Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.
GO:0098026	virus tail, tube	cellular_component	The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.
GO:0098027	virus tail, sheath	cellular_component	The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.
GO:0098028	virus tail, shaft	cellular_component	The tube of the non-contractile tails of some viruses.
GO:0098029	icosahedral viral capsid, spike	cellular_component	A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.
GO:0098030	icosahedral viral capsid, neck	cellular_component	A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).
GO:0098031	icosahedral viral capsid, collar	cellular_component	A small disk located at the base of some icosahedral virus capsids.
GO:0098032	icosahedral viral capsid, collar fiber	cellular_component	A fiber attached to the collar structure of some icosahedral viral capsids.
GO:0098033	icosahedral viral capsid, neck fiber	cellular_component	A fiber attached to the neck at the base of some icosahedral viral capsids.
GO:0098035	viral DNA genome packaging via site-specific sequence recognition	biological_process	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.
GO:0098036	viral DNA genome packaging, 3' extended cos packaging	biological_process	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.
GO:0098037	viral DNA genome packaging, 5' extended cos packaging	biological_process	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.
GO:0098038	non-replicative DNA transposition	biological_process	Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.
GO:0098039	replicative DNA transposition	biological_process	Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.
GO:0098045	virus baseplate assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.
GO:0098046	type V protein secretion system complex	cellular_component	A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).
GO:0098061	viral capsid, internal space	cellular_component	The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.
GO:0098505	G-rich strand telomeric DNA binding	molecular_function	Binding to G-rich, single-stranded, telomere-associated DNA.
GO:0098506	polynucleotide 3' dephosphorylation	biological_process	The process of removing one or more phosphate groups from the 3' end of a polynucleotide.
GO:0098507	polynucleotide 5' dephosphorylation	biological_process	The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
GO:0098508	endothelial to hematopoietic transition	biological_process	The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.
GO:0098509	sensory perception of humidity	biological_process	The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0098510	sensory perception of high humidity	biological_process	The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0098511	sensory perception of low humidity	biological_process	The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
GO:0098512	detection of humidity stimulus involved in sensory perception	biological_process	The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.
GO:0098513	detection of humidity	biological_process	The series of events in which a humidity stimulus is received and converted into a molecular signal.
GO:0098514	detection of high humidity stimulus involved in sensory perception	biological_process	The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.
GO:0098515	detection of low humidity stimulus involved in sensory perception	biological_process	The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity.
GO:0098516	detection of high humidity	biological_process	The series of events in which high humidity is detected and converted into a molecular signal.
GO:0098517	detection of low humidity	biological_process	The series of events in which low humidity is detected and converted into a molecular signal.
GO:0098520	excitatory neuromuscular junction	cellular_component	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.
GO:0098521	inhibitory neuromuscular junction	cellular_component	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.
GO:0098522	neuromuscular junction of skeletal muscle fiber	cellular_component	A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.
GO:0098523	neuromuscular junction of myotube	cellular_component	A neuromuscular junction in which the target muscle cell is a myotube.
GO:0098524	neuromuscular junction of somatic muscle myotube	cellular_component	A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.
GO:0098525	excitatory neuromuscular junction of somatic myotube	cellular_component	A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.
GO:0098526	inhibitory neuromuscular junction of somatic myotube	cellular_component	A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.
GO:0098527	neuromuscular junction of somatic muscle	cellular_component	A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.
GO:0098528	skeletal muscle fiber differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.
GO:0098529	neuromuscular junction development, skeletal muscle fiber	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.
GO:0098530	positive regulation of strand invasion	biological_process	Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
GO:0098531	ligand-activated transcription factor activity	molecular_function	A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.
GO:0098532	histone H3-K27 trimethylation	biological_process	The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.
GO:0098533	ATPase dependent transmembrane transport complex	cellular_component	A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
GO:0098534	centriole assembly	biological_process	A cellular process that results in the assembly of one or more centrioles.
GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	biological_process	Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.
GO:0098536	deuterosome	cellular_component	A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.
GO:0098538	lumenal side of transport vesicle membrane	cellular_component	The side (leaflet) of the transport vesicle membrane that faces the lumen.
GO:0098539	cytoplasmic side of transport vesicle membrane	cellular_component	The side (leaflet) of the transport vesicle membrane that faces the cytoplasm.
GO:0098540	lumenal side of trans-Golgi network transport vesicle membrane	cellular_component	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen.
GO:0098541	cytoplasmic side of trans-Golgi network transport vesicle membrane	cellular_component	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.
GO:0098542	defense response to other organism	biological_process	Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
GO:0098543	detection of other organism	biological_process	The series of events in which a stimulus from another organism is received and converted into a molecular signal.
GO:0098544	maintenance of protein complex location	biological_process	Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.
GO:0098545	maintenance of protein complex location in cytoplasm	biological_process	Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.
GO:0098547	lumenal side of Golgi membrane	cellular_component	The side of the Golgi membrane that faces the lumen.
GO:0098548	cytoplasmic side of Golgi membrane	cellular_component	The side (leaflet) of the Golgi membrane that faces the cytoplasm.
GO:0098549	somatic ring canal	cellular_component	A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.
GO:0098550	lumenal side of early endosome membrane	cellular_component	The side (leaflet) of the early endosome membrane that faces the lumen.
GO:0098551	lumenal side of late endosome membrane	cellular_component	The side (leaflet) of the late endosome membrane that faces the lumen.
GO:0098552	side of membrane	cellular_component	A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.
GO:0098553	lumenal side of endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the plasma membrane that faces the lumen.
GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the plasma membrane that faces the cytoplasm.
GO:0098555	lumenal side of rough endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen.
GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.
GO:0098557	cytoplasmic side of smooth endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm.
GO:0098558	lumenal side of smooth endoplasmic reticulum membrane	cellular_component	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.
GO:0098559	cytoplasmic side of early endosome membrane	cellular_component	The side (leaflet) of the early endosome membrane that faces the cytoplasm.
GO:0098560	cytoplasmic side of late endosome membrane	cellular_component	The side (leaflet) of the late endosome membrane that faces the cytoplasm.
GO:0098561	methyl accepting chemotaxis protein complex	cellular_component	A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.
GO:0098562	cytoplasmic side of membrane	cellular_component	The side of a membrane that faces the cytoplasm.
GO:0098564	trans-Golgi network transport vesicle lumen	cellular_component	The volume enclosed within the membrane of a trans-Golgi network transport vesicle.
GO:0098565	lumenal side of endosome membrane	cellular_component	The side (leaflet) of the endosome membrane that faces the lumen.
GO:0098566	transport vesicle lumen	cellular_component	The volume enclosed within the membrane of a transport vesicle.
GO:0098567	periplasmic side of plasma membrane	cellular_component	The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface.
GO:0098568	external side of mycolate outer membrane	cellular_component	The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface.
GO:0098569	internal side of mycolate outer membrane	cellular_component	The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.
GO:0098570	stromal side of plastid inner membrane	cellular_component	The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
GO:0098571	lumenal side of plastid thylakoid membrane	cellular_component	The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface.
GO:0098572	stromal side of plastid thylakoid membrane	cellular_component	The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
GO:0098574	cytoplasmic side of lysosomal membrane	cellular_component	The side (leaflet) of the lysosomal membrane that faces the cytoplasm.
GO:0098575	lumenal side of lysosomal membrane	cellular_component	The side (leaflet) of the lysosomal membrane that faces the lumen.
GO:0098576	lumenal side of membrane	cellular_component	Any side (leaflet) of a membrane that faces the lumen of an organelle.
GO:0098577	inactive sex chromosome	cellular_component	A sex chromosome that has been inactivated.
GO:0098578	condensed chromatin of inactivated sex chromosome	cellular_component	A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.
GO:0098579	active sex chromosome	cellular_component	A sex chromosome that has not been inactivated.
GO:0098581	detection of external biotic stimulus	biological_process	The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.
GO:0098582	innate vocalization behavior	biological_process	A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.
GO:0098583	learned vocalization behavior	biological_process	A vocalization behavior that is the result of learning.
GO:0098584	host cell synaptic vesicle	cellular_component	A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
GO:0098585	host cell synaptic vesicle membrane	cellular_component	The lipid bilayer surrounding a host synaptic vesicle.
GO:0098586	cellular response to virus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
GO:0098588	bounding membrane of organelle	cellular_component	The lipid bilayer that forms the outer-most layer of an organelle.
GO:0098590	plasma membrane region	cellular_component	A membrane that is a (regional) part of the plasma membrane.
GO:0098591	external side of apical plasma membrane	cellular_component	The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
GO:0098592	cytoplasmic side of apical plasma membrane	cellular_component	The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
GO:0098593	goblet cell theca	cellular_component	A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel.
GO:0098594	mucin granule	cellular_component	A secretory granule that contains mucin.
GO:0098595	perivitelline space	cellular_component	The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
GO:0098596	imitative learning	biological_process	Learning in which new behaviors are acquired through imitation.
GO:0098597	observational learning	biological_process	Learning that occurs through observing the behavior of others.
GO:0098598	learned vocalization behavior or vocal learning	biological_process	Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.
GO:0098599	palmitoyl hydrolase activity	molecular_function	Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
GO:0098600	selenomethionine gamma-lyase activity	molecular_function	Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.
GO:0098601	selenomethionine adenosyltransferase activity	molecular_function	Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.
GO:0098603	selenol Se-methyltransferase activity	molecular_function	Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.
GO:0098604	adenosylselenohomocysteinase activity	molecular_function	Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine.
GO:0098605	selenocystathionine beta-synthase activity	molecular_function	Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O.
GO:0098606	selenocystathionine gamma-lyase activity	molecular_function	Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.
GO:0098607	methylselenocysteine deselenhydrase activity	molecular_function	Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.
GO:0098608	methylselenol demethylase activity	molecular_function	Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.
GO:0098609	cell-cell adhesion	biological_process	The attachment of one cell to another cell via adhesion molecules.
GO:0098610	adhesion between unicellular organisms	biological_process	The attachment of two unicellular organisms to each other.
GO:0098613	methaneselenol methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide.
GO:0098614	hydrogen selenide methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol.
GO:0098615	dimethyl selenide methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.
GO:0098616	selenate adenylyltransferase (ATP) activity	molecular_function	Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate.
GO:0098617	adenylylselenate kinase activity	molecular_function	Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate.
GO:0098618	selenomethionine-tRNA ligase activity	molecular_function	Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).
GO:0098619	selenocysteine-tRNA ligase activity	molecular_function	Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.
GO:0098620	seryl-selenocysteinyl-tRNA kinase activity	molecular_function	Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.
GO:0098621	O-phosphoseryl-tRNA(Sec) selenium transferase activity	molecular_function	Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.
GO:0098622	selenodiglutathione-disulfide reductase (NADP) activity	molecular_function	Catalysis of the reaction: H+ + selenodiglutathione + NADPH = gluthathioselenol + glutathione + NADP+.
GO:0098623	selenite reductase activity	molecular_function	Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O.
GO:0098624	3'-phosphoadenylylselenate reductase activity	molecular_function	Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.
GO:0098625	methylselenol reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.
GO:0098626	methylseleninic acid reductase activity	molecular_function	Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.
GO:0098627	protein arginine phosphatase activity	molecular_function	Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate.
GO:0098628	peptidyl-N-phospho-arginine dephosphorylation	biological_process	The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.
GO:0098629	trans-Golgi network membrane organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
GO:0098630	aggregation of unicellular organisms	biological_process	The clustering together of unicellular organisms in suspension form aggregates.
GO:0098631	cell adhesion mediator activity	molecular_function	The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.
GO:0098632	cell-cell adhesion mediator activity	molecular_function	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
GO:0098633	collagen fibril binding	molecular_function	Binding to a collagen fibril.
GO:0098634	cell-matrix adhesion mediator activity	molecular_function	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix.
GO:0098635	protein complex involved in cell-cell adhesion	cellular_component	Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.
GO:0098636	protein complex involved in cell adhesion	cellular_component	Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
GO:0098637	protein complex involved in cell-matrix adhesion	cellular_component	Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.
GO:0098638	laminin binding involved in cell-matrix adhesion	molecular_function	Any laminin protein binding that occurs as part of cell-matrix adhesion.
GO:0098639	collagen binding involved in cell-matrix adhesion	molecular_function	Any collagen binding that occurs as part of cell-matrix adhesion.
GO:0098640	integrin binding involved in cell-matrix adhesion	molecular_function	Any integrin binding that occurs as part of the process of cell-matrix adhesion.
GO:0098641	cadherin binding involved in cell-cell adhesion	molecular_function	Any cadherin binding that occurs as part of the process of cell-cell adhesion.
GO:0098642	network-forming collagen trimer	cellular_component	A collagen trimer that forms networks.
GO:0098643	banded collagen fibril	cellular_component	A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).
GO:0098644	complex of collagen trimers	cellular_component	A complex of collagen trimers such as a fibril or collagen network.
GO:0098645	collagen network	cellular_component	A supramolecular complex that consists of collagen triple helices associated to form a network.
GO:0098646	collagen sheet	cellular_component	A protein complex that consists of collagen triple helices associated to form a sheet-like network.
GO:0098647	collagen beaded filament	cellular_component	A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure.
GO:0098648	collagen anchoring fibril	cellular_component	A specialised collagen fibril that functions as an anchor, binding to other collagen structures.
GO:0098650	peptidyl-proline 4-dioxygenase binding	molecular_function	Binding to a peptidyl-proline 4-dioxygenase.
GO:0098651	basement membrane collagen trimer	cellular_component	Any collagen timer that is part of a basement membrane.
GO:0098652	collagen type VII anchoring fibril	cellular_component	An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis.
GO:0098653	centromere clustering	biological_process	The process by which centromeres/kinetochores become localized to clusters.
GO:0098654	CENP-A recruiting complex	cellular_component	A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.
GO:0098655	monoatomic cation transmembrane transport	biological_process	The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.
GO:0098656	monoatomic anion transmembrane transport	biological_process	The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom.
GO:0098657	import into cell	biological_process	The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
GO:0098658	inorganic anion import across plasma membrane	biological_process	The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098659	inorganic cation import across plasma membrane	biological_process	The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098660	inorganic ion transmembrane transport	biological_process	The process in which an inorganic ion is transported across a membrane.
GO:0098661	inorganic anion transmembrane transport	biological_process	The process in which an inorganic anion is transported across a membrane.
GO:0098662	inorganic cation transmembrane transport	biological_process	A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0098664	G protein-coupled serotonin receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.
GO:0098665	serotonin receptor complex	cellular_component	A protein complex that is capable of serotonin receptor activity.
GO:0098666	G protein-coupled serotonin receptor complex	cellular_component	A protein complex that is capable of G protein-coupled serotonin receptor activity.
GO:0098669	superinfection exclusion	biological_process	The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.
GO:0098670	entry receptor-mediated virion attachment to host cell	biological_process	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.
GO:0098671	adhesion receptor-mediated virion attachment to host cell	biological_process	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located.
GO:0098672	inhibition of host CRISPR-cas system by virus	biological_process	A process by which a virus inhibits the CRISPR-cas system of its host.
GO:0098673	inhibition of host DNA replication by virus	biological_process	Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication.
GO:0098674	extrinsic component of neuronal dense core vesicle membrane	cellular_component	The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098676	modulation of host virulence by virus	biological_process	A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses.
GO:0098677	virion maturation	biological_process	Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.
GO:0098678	viral tropism switching	biological_process	A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase.
GO:0098680	template-free RNA nucleotidyltransferase	molecular_function	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template.
GO:0098681	synaptic ribbon	cellular_component	A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical.
GO:0098682	arciform density	cellular_component	An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane.
GO:0098683	cochlear hair cell ribbon synapse	cellular_component	A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.
GO:0098684	photoreceptor ribbon synapse	cellular_component	A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon.
GO:0098685	Schaffer collateral - CA1 synapse	cellular_component	A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
GO:0098686	hippocampal mossy fiber to CA3 synapse	cellular_component	One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.
GO:0098687	chromosomal region	cellular_component	Any subdivision of a chromosome along its length.
GO:0098688	parallel fiber to Purkinje cell synapse	cellular_component	An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
GO:0098689	latency-replication decision	biological_process	The process by which a virus switches on its replication cycle in an infected cell.  The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.
GO:0098690	glycinergic synapse	cellular_component	A synapse that uses glycine as a neurotransmitter.
GO:0098691	dopaminergic synapse	cellular_component	A synapse that uses dopamine as a neurotransmitter.
GO:0098692	noradrenergic synapse	cellular_component	A synapse that uses noradrenaline as a neurotransmitter.
GO:0098693	regulation of synaptic vesicle cycle	biological_process	Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.
GO:0098694	regulation of synaptic vesicle budding from presynaptic endocytic zone membrane	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.
GO:0098695	inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels	molecular_function	Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	biological_process	Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.
GO:0098697	ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels	molecular_function	Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:0098698	postsynaptic specialization assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
GO:0098699	structural constituent of presynaptic actin cytoskeleton	molecular_function	The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.
GO:0098700	neurotransmitter loading into synaptic vesicle	biological_process	The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps.
GO:0098702	adenine import across plasma membrane	biological_process	The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098703	calcium ion import across plasma membrane	biological_process	The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098704	carbohydrate import across plasma membrane	biological_process	The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098705	copper ion import across plasma membrane	biological_process	The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098706	iron ion import across cell outer membrane	biological_process	The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space.
GO:0098708	glucose import across plasma membrane	biological_process	The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098709	glutathione import across plasma membrane	biological_process	The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098710	guanine import across plasma membrane	biological_process	The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098711	iron ion import across plasma membrane	biological_process	The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098712	L-glutamate import across plasma membrane	biological_process	The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098713	leucine import across plasma membrane	biological_process	The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098714	malate import across plasma membrane	biological_process	The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098715	malonic acid import across plasma membrane	biological_process	The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098716	nickel cation import across plasma membrane	biological_process	The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098717	pantothenate import across plasma membrane	biological_process	The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098718	serine import across plasma membrane	biological_process	The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098719	sodium ion import across plasma membrane	biological_process	The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098720	succinate import across plasma membrane	biological_process	The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098721	uracil import across plasma membrane	biological_process	The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098722	asymmetric stem cell division	biological_process	Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.
GO:0098723	skeletal muscle myofibril	cellular_component	A myofibril of a skeletal muscle fiber.
GO:0098724	symmetric stem cell division	biological_process	Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.
GO:0098725	symmetric cell division	biological_process	Cell division in which both daughter cells are of the same type.
GO:0098726	symmetric division of skeletal muscle satellite stem cell	biological_process	The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells.
GO:0098727	maintenance of cell number	biological_process	Any process by which the numbers of cells of a particular type or in a tissue are maintained.
GO:0098728	germline stem cell asymmetric division	biological_process	The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.
GO:0098729	germline stem cell symmetric division	biological_process	Division of a germline stem cell to produce two germline stem cells of the same type as the parent.
GO:0098730	male germline stem cell symmetric division	biological_process	The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.
GO:0098731	skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration	biological_process	Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.
GO:0098732	macromolecule deacylation	biological_process	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.
GO:0098733	hemidesmosome associated protein complex	cellular_component	Any protein complex that is part of or has some part in a hemidesmosome.
GO:0098734	macromolecule depalmitoylation	biological_process	The removal of palymitoyl groups from a macromolecule.
GO:0098735	positive regulation of the force of heart contraction	biological_process	Any process that increases the force of heart muscle contraction.
GO:0098736	negative regulation of the force of heart contraction	biological_process	Any process that decreases the force of heart muscle contraction.
GO:0098737	protein insertion into plasma membrane	biological_process	The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
GO:0098739	import across plasma membrane	biological_process	The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	biological_process	The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
GO:0098743	cell aggregation	biological_process	The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
GO:0098744	1-phosphatidylinositol 4-kinase activator activity	molecular_function	Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.
GO:0098745	RNA decapping complex	cellular_component	A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.
GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter	biological_process	The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
GO:0098747	slow, calcium ion-dependent exocytosis of neurotransmitter	biological_process	The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.
GO:0098749	cerebellar neuron development	biological_process	The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0098750	FYXD domain binding	molecular_function	Binding to a FXYD domain.
GO:0098751	bone cell development	biological_process	The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
GO:0098754	detoxification	biological_process	Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0098755	maintenance of seed dormancy by absisic acid	biological_process	The process by which seed dormancy is maintained by the presence of absisic acid.
GO:0098756	response to interleukin-21	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
GO:0098757	cellular response to interleukin-21	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
GO:0098758	response to interleukin-8	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.
GO:0098759	cellular response to interleukin-8	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.
GO:0098760	response to interleukin-7	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
GO:0098761	cellular response to interleukin-7	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
GO:0098762	meiotic cell cycle phase	biological_process	One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GO:0098763	mitotic cell cycle phase	biological_process	One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
GO:0098764	meiosis I cell cycle phase	biological_process	A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.
GO:0098765	meiosis II cell cycle phase	biological_process	A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).
GO:0098768	meiotic prometaphase I	biological_process	The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.
GO:0098769	TIMP family protein binding	molecular_function	Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.
GO:0098770	FBXO family protein binding	molecular_function	Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.
GO:0098771	inorganic ion homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
GO:0098772	molecular function regulator activity	molecular_function	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0098773	skin epidermis development	biological_process	The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.
GO:0098774	curli	cellular_component	A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.
GO:0098775	curli assembly	biological_process	The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.
GO:0098776	protein transport across the cell outer membrane	biological_process	The directed movement of proteins across the cell outer membrane.
GO:0098777	protein secretion by the type VIII secretion system	biological_process	Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.
GO:0098778	curli subunit secretion coupled to curli assembly	biological_process	The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.
GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
GO:0098780	response to mitochondrial depolarisation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.
GO:0098781	ncRNA transcription	biological_process	The transcription of non (protein) coding RNA from a DNA template.
GO:0098782	mechanosensitived potassium channel activity	molecular_function	Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.
GO:0098784	biofilm matrix organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.
GO:0098785	biofilm matrix assembly	biological_process	A process that results in the assembly of a biofilm matrix.
GO:0098786	biofilm matrix disassembly	biological_process	A process that results in the disassembly of a biofilm matrix.
GO:0098788	dendritic knob	cellular_component	The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.
GO:0098790	ncRNA transcription associated with protein coding gene TSS/TES	biological_process	The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes.
GO:0098791	Golgi apparatus subcompartment	cellular_component	A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.
GO:0098792	xenophagy	biological_process	The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.
GO:0098793	presynapse	cellular_component	The part of a synapse that is part of the presynaptic cell.
GO:0098794	postsynapse	cellular_component	The part of a synapse that is part of the post-synaptic cell.
GO:0098795	global gene silencing by mRNA cleavage	biological_process	A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner.
GO:0098796	membrane protein complex	cellular_component	Any protein complex that is part of a membrane.
GO:0098797	plasma membrane protein complex	cellular_component	Any protein complex that is part of the plasma membrane.
GO:0098798	mitochondrial protein-containing complex	cellular_component	A protein complex that is part of a mitochondrion.
GO:0098799	outer mitochondrial membrane protein complex	cellular_component	Any protein complex that is part of the outer mitochondrial membrane.
GO:0098800	inner mitochondrial membrane protein complex	cellular_component	Any protein complex that is part of the inner mitochondrial membrane.
GO:0098801	regulation of renal system process	biological_process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.
GO:0098802	plasma membrane signaling receptor complex	cellular_component	Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
GO:0098803	respiratory chain complex	cellular_component	Any protein complex that is part of a respiratory chain.
GO:0098804	non-motile cilium membrane	cellular_component	The portion of the plasma membrane surrounding a non-motile cilium.
GO:0098807	chloroplast thylakoid membrane protein complex	cellular_component	A protein complex that is part of a chloroplast thylakoid membrane.
GO:0098808	mRNA cap binding	molecular_function	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.
GO:0098809	nitrite reductase activity	molecular_function	Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor.
GO:0098810	neurotransmitter reuptake	biological_process	The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol.
GO:0098813	nuclear chromosome segregation	biological_process	The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
GO:0098814	spontaneous synaptic transmission	biological_process	The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
GO:0098815	modulation of excitatory postsynaptic potential	biological_process	Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
GO:0098816	mini excitatory postsynaptic potential	biological_process	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.
GO:0098817	evoked excitatory postsynaptic potential	biological_process	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.
GO:0098818	hyperpolarization of postsynaptic membrane	biological_process	A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.
GO:0098819	depolarization of postsynaptic membrane	biological_process	A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.
GO:0098820	trans-synaptic protein complex	cellular_component	A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.
GO:0098821	BMP receptor activity	molecular_function	Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.
GO:0098822	peptidyl-cysteine modification to L-cysteine persulfide	biological_process	The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide.
GO:0098823	peptidyl-cysteine modification to S-amindino-L-cysteine	biological_process	The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.
GO:0098824	peptidyl-cysteine sulfation	biological_process	The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.
GO:0098825	peptidyl-histidine guanylation	biological_process	The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.
GO:0098826	endoplasmic reticulum tubular network membrane	cellular_component	The membrane of the endoplasmic reticulum tubular network.
GO:0098827	endoplasmic reticulum subcompartment	cellular_component	A distinct region of the endoplasmic reticulum.
GO:0098828	modulation of inhibitory postsynaptic potential	biological_process	Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
GO:0098829	intestinal folate absorption	biological_process	Uptake of folic into the blood by absorption from the small intestine.
GO:0098830	presynaptic endosome	cellular_component	An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles.
GO:0098831	presynaptic active zone cytoplasmic component	cellular_component	A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles.
GO:0098832	peri-centrosomal recycling endosome	cellular_component	A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.
GO:0098833	presynaptic endocytic zone	cellular_component	A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity.
GO:0098834	presynaptic endocytic zone cytoplasmic component	cellular_component	The cytoplasmic component of the presynaptic endocytic zone.
GO:0098835	presynaptic endocytic zone membrane	cellular_component	The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.
GO:0098836	cytoskeleton of dendritic spine	cellular_component	The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodeling in response to postsynaptic signaling.
GO:0098837	postsynaptic recycling endosome	cellular_component	A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signaling and so can play a role in long term potentiation.
GO:0098838	folate transmembrane transport	biological_process	The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane.
GO:0098839	postsynaptic density membrane	cellular_component	The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
GO:0098840	protein transport along microtubule	biological_process	The directed movement of a protein along a microtubule, mediated by motor proteins.
GO:0098841	protein localization to cell division site after cytokinesis	biological_process	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.
GO:0098842	postsynaptic early endosome	cellular_component	An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.
GO:0098843	postsynaptic endocytic zone	cellular_component	A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins.
GO:0098844	postsynaptic endocytic zone membrane	cellular_component	The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.
GO:0098845	postsynaptic endosome	cellular_component	An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.
GO:0098846	podocyte foot	cellular_component	A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.
GO:0098847	sequence-specific single stranded DNA binding	molecular_function	Binding to single-stranded DNA of a specific nucleotide composition.
GO:0098848	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity	molecular_function	Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.
GO:0098849	cellular detoxification of cadmium ion	biological_process	Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
GO:0098850	extrinsic component of synaptic vesicle membrane	cellular_component	The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098851	double-stranded miRNA binding	molecular_function	Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.
GO:0098852	lytic vacuole membrane	cellular_component	The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.
GO:0098853	endoplasmic reticulum-vacuole membrane contact site	cellular_component	A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.
GO:0098854	podocyte primary projection	cellular_component	A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.
GO:0098855	HCN channel complex	cellular_component	A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.
GO:0098856	intestinal lipid absorption	biological_process	Any process in which lipids are taken up from the contents of the intestine.
GO:0098857	membrane microdomain	cellular_component	A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.
GO:0098858	actin-based cell projection	cellular_component	A cell projection supported by an assembly of actin filaments, and which lacks microtubules.
GO:0098859	actin filament bundle of actin-based cell projection	cellular_component	A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments.
GO:0098860	actin filament bundle of stereocilium	cellular_component	A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.
GO:0098861	actin filament bundle of filopodium	cellular_component	A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.
GO:0098862	cluster of actin-based cell projections	cellular_component	A cell part consisting of multiple, closely packed actin-based cell projections.
GO:0098863	nuclear migration by microtubule mediated pushing forces	biological_process	The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.
GO:0098864	stabilization of host tight cell-cell junction	biological_process	The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
GO:0098865	disruption of host tight cell-cell junction	biological_process	The process by which a symbiont effects a change in the structure or function of tight cell-cell junctions between cells of the host. Tight cell-cell junctions, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
GO:0098866	multivesicular body fusion to apical plasma membrane	biological_process	The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.
GO:0098867	intramembranous bone growth	biological_process	The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.
GO:0098868	bone growth	biological_process	The increase in size or mass of a bone that contributes to the shaping of that bone.
GO:0098869	cellular oxidant detoxification	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
GO:0098870	action potential propagation	biological_process	The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold.
GO:0098871	postsynaptic actin cytoskeleton	cellular_component	The actin cytoskeleton that is part of a postsynapse.
GO:0098872	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse.
GO:0098873	neuronal action potential back-propagation	biological_process	Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.
GO:0098874	spike train	biological_process	A series of sequential, propagated action potentials occurring in a single cell.
GO:0098875	epididymosome	cellular_component	A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins.
GO:0098876	vesicle-mediated transport to the plasma membrane	biological_process	The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.
GO:0098877	neurotransmitter receptor transport to plasma membrane	biological_process	The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.
GO:0098878	neurotransmitter receptor complex	cellular_component	Any protein complex that is capable of functioning as a neurotransmitter receptor.
GO:0098879	structural constituent of postsynaptic specialization	molecular_function	The action of a molecule that contributes to the structural integrity of a postsynaptic specialization.
GO:0098880	maintenance of postsynaptic specialization structure	biological_process	A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.
GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane	biological_process	The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.
GO:0098882	structural constituent of presynaptic active zone	molecular_function	The action of a molecule that contributes to the structural integrity of a presynaptic active zone.
GO:0098883	synapse pruning	biological_process	A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
GO:0098884	postsynaptic neurotransmitter receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.
GO:0098885	modification of postsynaptic actin cytoskeleton	biological_process	Any process that modifies the structure of a postsynaptic actin cytoskeleton.
GO:0098886	modification of dendritic spine	biological_process	Any process that modifies the structure of a dendritic spine.
GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	biological_process	The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
GO:0098888	extrinsic component of presynaptic membrane	cellular_component	The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098890	extrinsic component of postsynaptic membrane	cellular_component	The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098891	extrinsic component of presynaptic active zone membrane	cellular_component	The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098892	extrinsic component of postsynaptic specialization membrane	cellular_component	The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098893	extrinsic component of postsynaptic endocytic zone	cellular_component	The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098894	extrinsic component of presynaptic endocytic zone membrane	cellular_component	The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098895	postsynaptic endosome membrane	cellular_component	The lipid bilayer surrounding a postsynaptic endosome.
GO:0098896	postsynaptic early endosome membrane	cellular_component	The lipid bilayer surrounding a postsynaptic early endosome.
GO:0098897	spine apparatus membrane	cellular_component	The lipid bilayer surrounding the spine apparatus.
GO:0098898	dense core granule lumen	cellular_component	The volume enclosed by the dense core granule membrane.
GO:0098899	spine apparatus lumen	cellular_component	The volume enclosed by the spine apparatus membrane.
GO:0098900	regulation of action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098901	regulation of cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098902	regulation of membrane depolarization during action potential	biological_process	Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.
GO:0098903	regulation of membrane repolarization during action potential	biological_process	Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.
GO:0098904	regulation of AV node cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098905	regulation of bundle of His cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098906	regulation of Purkinje myocyte action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098907	regulation of SA node cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098908	regulation of neuronal action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.
GO:0098910	regulation of atrial cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098911	regulation of ventricular cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential	biological_process	The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0098913	membrane depolarization during ventricular cardiac muscle cell action potential	biological_process	The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	biological_process	The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	biological_process	The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
GO:0098916	anterograde trans-synaptic signaling	biological_process	Cell-cell signaling from pre to post-synapse, across the synaptic cleft.
GO:0098917	retrograde trans-synaptic signaling	biological_process	Cell-cell signaling from post to pre-synapse, across the synaptic cleft.
GO:0098918	structural constituent of synapse	molecular_function	The action of a molecule that contributes to the structural integrity of a synapse.
GO:0098919	structural constituent of postsynaptic density	molecular_function	The action of a molecule that contributes to the structural integrity of a postsynaptic density.
GO:0098920	retrograde trans-synaptic signaling by lipid	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.
GO:0098921	retrograde trans-synaptic signaling by endocannabinoid	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand.
GO:0098922	extrinsic component of dense core granule membrane	cellular_component	The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098923	retrograde trans-synaptic signaling by soluble gas	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.
GO:0098924	retrograde trans-synaptic signaling by nitric oxide	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
GO:0098925	retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission	biological_process	Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
GO:0098926	postsynaptic signal transduction	biological_process	Signal transduction in which the initial step occurs in a postsynapse.
GO:0098927	vesicle-mediated transport between endosomal compartments	biological_process	A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.
GO:0098928	presynaptic signal transduction	biological_process	Signal transduction in which the initial step occurs in a presynapse.
GO:0098930	axonal transport	biological_process	The directed movement of organelles or molecules along microtubules in axons.
GO:0098931	virion attachment to host cell flagellum	biological_process	The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.
GO:0098932	disruption by virus of host cell wall peptidoglycan during virus entry	biological_process	A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry.
GO:0098933	disruption by symbiont of host cell envelope	biological_process	The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0098934	retrograde dendritic transport	biological_process	The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.
GO:0098935	dendritic transport	biological_process	The directed movement of organelles or molecules along microtubules in dendrites.
GO:0098937	anterograde dendritic transport	biological_process	The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.
GO:0098938	actin cytoskeleton of dendritic spine	cellular_component	The actin cytoskeleton that is part of a dendritic spine.
GO:0098939	dendritic transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in nerve cell dendrites.
GO:0098940	anterograde trans-synaptic signaling by nitric oxide	biological_process	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.
GO:0098941	anterograde trans-synaptic signaling by trans-synaptic protein complex	biological_process	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.
GO:0098942	retrograde trans-synaptic signaling by trans-synaptic protein complex	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.
GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	biological_process	The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.
GO:0098944	postsynaptic recycling endosome membrane	cellular_component	The lipid bilayer surrounding a postsynaptic recycling endosome.
GO:0098953	receptor diffusion trapping	biological_process	The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.
GO:0098954	presynaptic endosome membrane	cellular_component	The lipid bilayer surrounding a presynaptic endosome.
GO:0098957	anterograde axonal transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
GO:0098958	retrograde axonal transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.
GO:0098959	retrograde dendritic transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.
GO:0098960	postsynaptic neurotransmitter receptor activity	molecular_function	Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission.
GO:0098961	dendritic transport of ribonucleoprotein complex	biological_process	The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.
GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	biological_process	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
GO:0098963	dendritic transport of messenger ribonucleoprotein complex	biological_process	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.
GO:0098964	anterograde dendritic transport of messenger ribonucleoprotein complex	biological_process	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.
GO:0098965	extracellular matrix of synaptic cleft	cellular_component	The portion of the extracellular matrix that lies within the synaptic cleft.
GO:0098966	perisynaptic extracellular matrix	cellular_component	The portion of the extracellular matrix that lies within the perisynaptic space.
GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	biological_process	The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.
GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome	biological_process	Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	biological_process	The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.
GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	biological_process	The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.
GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex	biological_process	The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
GO:0098972	anterograde dendritic transport of mitochondrion	biological_process	The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	molecular_function	The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.
GO:0098974	postsynaptic actin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.
GO:0098975	postsynapse of neuromuscular junction	cellular_component	The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.
GO:0098976	excitatory chemical synaptic transmission	biological_process	Synaptic transmission that results in an excitatory postsynaptic potential.
GO:0098977	inhibitory chemical synaptic transmission	biological_process	Synaptic transmission that results in an inhibitory postsynaptic potential.
GO:0098978	glutamatergic synapse	cellular_component	A synapse that uses glutamate as a neurotransmitter.
GO:0098979	polyadic synapse	cellular_component	A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.
GO:0098980	presynaptic density	cellular_component	An electron dense specialization of the presynaptic active zone cytoskeleton.
GO:0098981	cholinergic synapse	cellular_component	A synapse that uses acetylcholine as a neurotransmitter.
GO:0098982	GABA-ergic synapse	cellular_component	A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
GO:0098983	symmetric, GABA-ergic, inhibitory synapse	cellular_component	A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.
GO:0098984	neuron to neuron synapse	cellular_component	A synapse in which pre and post-synaptic cells are neurons.
GO:0098985	asymmetric, glutamatergic, excitatory synapse	cellular_component	A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.
GO:0098986	T-bar	cellular_component	A T-shaped presynpatic density. These are common in arhropod central nervous systems.
GO:0098987	regulation of modification of synapse structure, modulating synaptic transmission	biological_process	Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.
GO:0098988	G protein-coupled glutamate receptor activity	molecular_function	Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.
GO:0098989	NMDA selective glutamate receptor signaling pathway	biological_process	The series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0098990	AMPA selective glutamate receptor signaling pathway	biological_process	The series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0098991	kainate selective glutamate receptor signaling pathway	biological_process	The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0098992	neuronal dense core vesicle	cellular_component	A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
GO:0098994	disruption of host cell envelope during viral entry	biological_process	The disruption of host cell envelope by viral proteins during virus entry.
GO:0098995	disruption by virus of host envelope lipopolysaccharide during virus entry	biological_process	The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides.
GO:0098996	disruption of host cell glycocalyx during viral entry	biological_process	The disruption of host cell glycocalyx by viral proteins during virus entry.
GO:0098997	fusion of virus membrane with host outer membrane	biological_process	Fusion of a viral membrane with the host cell outer membrane during viral entry.
GO:0098998	extrinsic component of postsynaptic early endosome membrane	cellular_component	The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0098999	extrinsic component of postsynaptic endosome membrane	cellular_component	The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099000	viral genome ejection through host cell envelope, contractile tail mechanism	biological_process	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath.  Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope.
GO:0099001	viral genome ejection through host cell envelope, long flexible tail mechanism	biological_process	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm.
GO:0099002	viral genome ejection through host cell envelope, short tail mechanism	biological_process	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties.
GO:0099003	vesicle-mediated transport in synapse	biological_process	Any vesicle-mediated transport that occurs in a synapse.
GO:0099004	calmodulin dependent kinase signaling pathway	biological_process	Any signal transduction pathway involving calmodulin dependent kinase activity.
GO:0099005	extrinsic component of postsynaptic recycling endosome membrane	cellular_component	The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099006	viral entry via permeabilization of endosomal membrane	biological_process	The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.
GO:0099007	extrinsic component of presynaptic endosome membrane	cellular_component	The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099008	viral entry via permeabilization of inner membrane	biological_process	The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane.
GO:0099009	viral genome circularization	biological_process	The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities.
GO:0099010	modification of postsynaptic structure	biological_process	Any process that modifies the structure of a postsynapse.
GO:0099011	neuronal dense core vesicle exocytosis	biological_process	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.
GO:0099012	neuronal dense core vesicle membrane	cellular_component	The lipid bilayer surrounding a neuronal dense core vesicle.
GO:0099013	neuronal dense core vesicle lumen	cellular_component	The volume enclosed by a neuronal dense core vesicle membrane.
GO:0099014	neuronal dense core vesicle organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.
GO:0099015	degradation of host chromosome by virus	biological_process	The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.
GO:0099016	evasion by virus of DNA end degradation	biological_process	A process by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases.
GO:0099017	maintenance of protein localization at cell tip	biological_process	Any process in which localization of a protein is maintained at the cell tip.
GO:0099018	evasion by virus of host restriction-modification system	biological_process	Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction.
GO:0099019	maintenance of protein localization at growing cell tip	biological_process	Any process in which localization of a protein is maintained at the growing cell tip.
GO:0099020	perinuclear endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the perinuclear endoplasmic reticulum.
GO:0099021	cortical endoplasmic reticulum lumen	cellular_component	The volume enclosed by the membranes of the cortical endoplasmic reticulum.
GO:0099022	vesicle tethering	biological_process	The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.
GO:0099023	vesicle tethering complex	cellular_component	Any protein complex that plays a role in vesicle tethering.
GO:0099024	plasma membrane invagination	biological_process	An infolding of the plasma membrane.
GO:0099038	ceramide floppase activity	molecular_function	Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0099039	sphingolipid translocation	biological_process	The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
GO:0099040	ceramide translocation	biological_process	The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.
GO:0099041	vesicle tethering to Golgi	biological_process	The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
GO:0099043	cargo loading involved in clathrin-dependent endocytosis	biological_process	Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat.
GO:0099044	vesicle tethering to endoplasmic reticulum	biological_process	The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
GO:0099045	viral extrusion	biological_process	The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.
GO:0099046	clearance of foreign intracellular nucleic acids	biological_process	A defense process that protects an organism from DNA or RNA from an invading organism.
GO:0099047	clearance of foreign intracellular RNA	biological_process	A defense process that protects an organism from invading foreign RNA.
GO:0099048	CRISPR-cas system	biological_process	A defense response of that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.
GO:0099049	clathrin coat assembly involved in endocytosis	biological_process	The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.
GO:0099050	vesicle scission	biological_process	The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.
GO:0099051	vesicle scission involved in endocytosis	biological_process	The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.
GO:0099052	vesicle scission involved in clathrin-mediated endocytosis	biological_process	The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.
GO:0099053	activating signal cointegrator 1 complex	cellular_component	A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.
GO:0099054	presynapse assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a presynapse.
GO:0099068	postsynapse assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a postsynapse.
GO:0099069	synaptic vesicle tethering involved in synaptic vesicle exocytosis	biological_process	The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.
GO:0099070	static microtubule bundle	cellular_component	A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.
GO:0099071	dynamic microtubule bundle	cellular_component	A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	biological_process	Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.
GO:0099073	mitochondrion-derived vesicle	cellular_component	A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae.
GO:0099074	mitochondrion to lysosome transport	biological_process	Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles.
GO:0099075	mitochondrion-derived vesicle mediated transport	biological_process	Transport from the mitochondrion, mediated by mitochondrion derived vesicles.
GO:0099076	mitochondrion to peroxisome transport	biological_process	Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles.
GO:0099077	histone-dependent DNA binding	molecular_function	DNA-binding activity that is dependent on binding to a histone.
GO:0099078	BORC complex	cellular_component	A protein complex that is involved in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.
GO:0099079	actin body	cellular_component	An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.
GO:0099080	supramolecular complex	cellular_component	A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
GO:0099081	supramolecular polymer	cellular_component	A polymeric supramolecular structure.
GO:0099082	retrograde trans-synaptic signaling by neuropeptide	biological_process	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.
GO:0099083	retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological_process	Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.
GO:0099084	postsynaptic specialization organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
GO:0099085	DIF dechlorinase activity	molecular_function	Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.
GO:0099086	synaptonemal structure	cellular_component	A proteinaceous scaffold found between homologous chromosomes during meiosis.
GO:0099087	anterograde axonal transport of messenger ribonucleoprotein complex	biological_process	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse.
GO:0099088	axonal transport of messenger ribonucleoprotein complex	biological_process	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons.
GO:0099089	establishment of endoplasmic reticulum localization to postsynapse	biological_process	The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.
GO:0099091	postsynaptic specialization, intracellular component	cellular_component	A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GO:0099092	postsynaptic density, intracellular component	cellular_component	A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GO:0099093	calcium export from the mitochondrion	biological_process	A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.
GO:0099094	ligand-gated monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0099095	ligand-gated monoatomic anion channel activity	molecular_function	Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0099096	vestibular calyx terminal	cellular_component	The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell.
GO:0099098	microtubule polymerization based movement	biological_process	The movement of a cellular component as a result of microtubule polymerization.
GO:0099099	G-protein gated monoatomic ion channel activity	molecular_function	An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.
GO:0099100	G-protein gated monoatomic cation channel activity	molecular_function	A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.
GO:0099101	G-protein gated potassium channel activity	molecular_function	A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer.
GO:0099102	G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential	molecular_function	Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential.
GO:0099103	channel activator activity	molecular_function	Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
GO:0099104	potassium channel activator activity	molecular_function	Binds to and increases the activity of a potassium channel, resulting in its opening.
GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.
GO:0099106	ion channel regulator activity	molecular_function	Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
GO:0099107	ion channel regulator activity involved in G protein-coupled receptor signaling pathway	molecular_function	Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling.
GO:0099108	potassium channel activator activity involved in G protein-coupled receptor signaling pathway	molecular_function	Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling.
GO:0099109	potassium channel activating, G protein-coupled receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.
GO:0099110	microtubule polymerization based protein transport to cell tip cortex	biological_process	The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached.
GO:0099111	microtubule-based transport	biological_process	A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GO:0099112	microtubule polymerization based protein transport	biological_process	The transport of a protein driven by polymerization of a microtubule to which it is attached.
GO:0099113	negative regulation of presynaptic cytosolic calcium concentration	biological_process	Any process that decreases the concentration of calcium ions in the presynaptic cytosol.
GO:0099115	chromosome, subtelomeric region	cellular_component	A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin.
GO:0099116	tRNA 5'-end processing	biological_process	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.
GO:0099117	protein transport along microtubule to cell tip	biological_process	The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins.
GO:0099118	microtubule-based protein transport	biological_process	A microtubule-based process that results in the transport of proteins.
GO:0099119	3-demethylubiquinol-8 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8.
GO:0099120	socially cooperative development	biological_process	The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.
GO:0099121	fungal sorus development	biological_process	The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.
GO:0099122	RNA polymerase II C-terminal domain binding	molecular_function	Binding to the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
GO:0099123	somato-dendritic dopamine secretion	biological_process	The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.
GO:0099124	axonal dopamine secretion	biological_process	The regulated release of dopamine from an axon.
GO:0099125	PAK family kinase-Sog2 complex	cellular_component	A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network.
GO:0099126	transforming growth factor beta complex	cellular_component	A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP.
GO:0099128	mitochondrial iron-sulfur cluster assembly complex	cellular_component	A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.
GO:0099129	cochlear outer hair cell electromotile response	biological_process	A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification.
GO:0099130	estrogen binding	molecular_function	Binding to an estrogen.
GO:0099134	chimeric sorocarp development	biological_process	Development of a sorocarp formed by aggregation of cells with different genotypes.
GO:0099135	chimeric colonial development	biological_process	Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.
GO:0099136	chimeric non-reproductive fruiting body development	biological_process	Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.
GO:0099137	altruistic, chimeric, non-reproductive fruiting body development	biological_process	Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.
GO:0099138	altruistic, chimeric sorocarp development	biological_process	Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.
GO:0099139	cheating during chimeric sorocarp development	biological_process	Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.
GO:0099140	presynaptic actin cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.
GO:0099141	cellular response to protozoan	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
GO:0099142	intracellularly ATP-gated ion channel activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
GO:0099143	presynaptic actin cytoskeleton	cellular_component	The actin cytoskeleton that is part of a presynapse.
GO:0099145	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane	biological_process	Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.
GO:0099147	extrinsic component of postsynaptic density membrane	cellular_component	The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099148	regulation of synaptic vesicle docking	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle docking.
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	biological_process	Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.
GO:0099150	regulation of postsynaptic specialization assembly	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.
GO:0099151	regulation of postsynaptic density assembly	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	biological_process	Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
GO:0099153	synaptic transmission, serotonergic	biological_process	The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0099154	serotonergic synapse	cellular_component	A synapse that uses serotonin as a neurotransmitter.
GO:0099155	synaptic transmission, noradrenergic	biological_process	The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
GO:0099156	cell-cell signaling via exosome	biological_process	Cell-cell signaling in which the ligand is carried between cells by an exosome.
GO:0099157	trans-synaptic signaling via exosome	biological_process	Transynaptic signaling in which the ligand is carried across the synapse by an exosome.
GO:0099158	regulation of recycling endosome localization within postsynapse	biological_process	Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.
GO:0099159	regulation of modification of postsynaptic structure	biological_process	Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.
GO:0099160	postsynaptic intermediate filament cytoskeleton	cellular_component	The intermediate filament cytoskeleton that is part of a postsynapse.
GO:0099161	regulation of presynaptic dense core granule exocytosis	biological_process	Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.
GO:0099162	regulation of neurotransmitter loading into synaptic vesicle	biological_process	Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.
GO:0099163	synaptic signaling by nitric oxide	biological_process	Cell-cell signaling to or from a synapse, mediated by nitric oxide.
GO:0099164	postsynaptic specialization membrane of symmetric synapse	cellular_component	The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
GO:0099165	postsynaptic specialization of symmetric synapse, intracellular component	cellular_component	A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses.
GO:0099170	postsynaptic modulation of chemical synaptic transmission	biological_process	Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.
GO:0099171	presynaptic modulation of chemical synaptic transmission	biological_process	Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.
GO:0099172	presynapse organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.
GO:0099173	postsynapse organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.
GO:0099174	regulation of presynapse organization	biological_process	Any process that modulates the physical form of a presynapse.
GO:0099175	regulation of postsynapse organization	biological_process	Any process that modulates the physical form of a postsynapse.
GO:0099176	regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex	biological_process	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.
GO:0099177	regulation of trans-synaptic signaling	biological_process	Any process that modulates the frequency, rate or extent of trans-synaptic signaling.
GO:0099178	regulation of retrograde trans-synaptic signaling by endocanabinoid	biological_process	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid.
GO:0099179	regulation of synaptic membrane adhesion	biological_process	Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.
GO:0099180	zinc ion import into synaptic vesicle	biological_process	The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.
GO:0099181	structural constituent of presynapse	molecular_function	The action of a molecule that contributes to the structural integrity of a presynapse.
GO:0099182	presynaptic intermediate filament cytoskeleton	cellular_component	The intermediate filament cytoskeleton that is part of a presynapse.
GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse.
GO:0099184	structural constituent of postsynaptic intermediate filament cytoskeleton	molecular_function	The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.
GO:0099185	postsynaptic intermediate filament cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.
GO:0099186	structural constituent of postsynapse	molecular_function	The action of a molecule that contributes to the structural integrity of a postsynapse.
GO:0099187	presynaptic cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.
GO:0099188	postsynaptic cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.
GO:0099189	postsynaptic spectrin-associated cytoskeleton	cellular_component	The portion of the spectrin-associated cytoskeleton contained within the postsynapse.
GO:0099190	postsynaptic spectrin-associated cytoskeleton organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.
GO:0099191	trans-synaptic signaling by BDNF	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.
GO:0099192	cerebellar Golgi cell to granule cell synapse	cellular_component	A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.
GO:0099243	extrinsic component of synaptic membrane	cellular_component	The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099400	caveola neck	cellular_component	A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.
GO:0099401	caveola bulb	cellular_component	The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins.
GO:0099402	plant organ development	biological_process	Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
GO:0099403	maintenance of mitotic sister chromatid cohesion, telomeric	biological_process	The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
GO:0099404	mitotic sister chromatid cohesion, telomeric	biological_process	The cell cycle process in which telomeres of sister chromatids are joined during mitosis.
GO:0099500	vesicle fusion to plasma membrane	biological_process	Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
GO:0099501	exocytic vesicle membrane	cellular_component	The lipid bilayer surrounding an exocytic vesicle.
GO:0099502	calcium-dependent activation of synaptic vesicle fusion	biological_process	The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.
GO:0099503	secretory vesicle	cellular_component	A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
GO:0099504	synaptic vesicle cycle	biological_process	A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.
GO:0099505	regulation of presynaptic membrane potential	biological_process	Any process that modulates the potential difference across a presynaptic membrane.
GO:0099506	synaptic vesicle transport along actin filament	biological_process	The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	molecular_function	Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	molecular_function	Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	biological_process	Any process that regulates the concentration of calcium in the presynaptic cytosol.
GO:0099510	calcium ion binding involved in regulation of cytosolic calcium ion concentration	molecular_function	The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations.
GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	molecular_function	Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.
GO:0099512	supramolecular fiber	cellular_component	A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GO:0099513	polymeric cytoskeletal fiber	cellular_component	A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
GO:0099514	synaptic vesicle cytoskeletal transport	biological_process	The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.
GO:0099515	actin filament-based transport	biological_process	The transport of organelles or other particles from one location in the cell to another along actin filaments.
GO:0099517	synaptic vesicle transport along microtubule	biological_process	The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.
GO:0099518	vesicle cytoskeletal trafficking	biological_process	The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.
GO:0099519	dense core granule cytoskeletal transport	biological_process	The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.
GO:0099520	monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential	molecular_function	Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
GO:0099521	ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential	molecular_function	Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
GO:0099522	cytosolic region	cellular_component	Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.
GO:0099523	presynaptic cytosol	cellular_component	The region of the cytosol consisting of all cytosol that is part of the presynapse.
GO:0099524	postsynaptic cytosol	cellular_component	The region of the cytosol consisting of all cytosol that is part of the postsynapse.
GO:0099525	presynaptic dense core vesicle exocytosis	biological_process	The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.
GO:0099526	presynapse to nucleus signaling pathway	biological_process	The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
GO:0099527	postsynapse to nucleus signaling pathway	biological_process	The series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
GO:0099528	G protein-coupled neurotransmitter receptor activity	molecular_function	Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	molecular_function	Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).
GO:0099530	G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential	molecular_function	A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.
GO:0099531	presynaptic process involved in chemical synaptic transmission	biological_process	The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.
GO:0099532	synaptic vesicle endosomal processing	biological_process	The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
GO:0099533	positive regulation of presynaptic cytosolic calcium concentration	biological_process	Any process that increases the concentration of calcium ions in the presynaptic cytosol.
GO:0099534	calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration	molecular_function	The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations.
GO:0099535	synapse-associated extracellular matrix	cellular_component	The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.
GO:0099536	synaptic signaling	biological_process	Cell-cell signaling to, from or within a synapse.
GO:0099537	trans-synaptic signaling	biological_process	Cell-cell signaling in either direction across the synaptic cleft.
GO:0099538	synaptic signaling via neuropeptide	biological_process	Cell-cell signaling to or from a synapse, mediated by a peptide.
GO:0099539	neuropeptide secretion from presynapse	biological_process	The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration.
GO:0099540	trans-synaptic signaling by neuropeptide	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.
GO:0099541	trans-synaptic signaling by lipid	biological_process	Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.
GO:0099542	trans-synaptic signaling by endocannabinoid	biological_process	Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.
GO:0099543	trans-synaptic signaling by soluble gas	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.
GO:0099544	perisynaptic space	cellular_component	The extracellular region immediately adjacent to to a synapse.
GO:0099545	trans-synaptic signaling by trans-synaptic complex	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.
GO:0099546	protein catabolic process, modulating synaptic transmission	biological_process	Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.
GO:0099547	regulation of translation at synapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating translation occurring at the synapse.
GO:0099548	trans-synaptic signaling by nitric oxide	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.
GO:0099549	trans-synaptic signaling by carbon monoxide	biological_process	Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.
GO:0099550	trans-synaptic signaling, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.
GO:0099551	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.
GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.
GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.
GO:0099554	trans-synaptic signaling by soluble gas, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.
GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.
GO:0099556	trans-synaptic signaling by carbon monoxide, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.
GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	biological_process	Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.
GO:0099558	maintenance of synapse structure	biological_process	A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.
GO:0099559	maintenance of alignment of postsynaptic density and presynaptic active zone	biological_process	The process by which alignment between postsynaptic density and presynaptic active zone is maintained.
GO:0099560	synaptic membrane adhesion	biological_process	The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
GO:0099561	synaptic membrane adhesion to extracellular matrix	biological_process	The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.
GO:0099562	maintenance of postsynaptic density structure	biological_process	A process which maintains the organization and the arrangement of proteins in the presynaptic density.
GO:0099563	modification of synaptic structure	biological_process	Any process that modifies the structure/morphology of a synapse.
GO:0099564	modification of synaptic structure, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission via modification of the structure of the synapse.
GO:0099565	chemical synaptic transmission, postsynaptic	biological_process	The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.
GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	biological_process	Any process that regulates the concentration of calcium in the postsynaptic cytosol.
GO:0099567	calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.
GO:0099568	cytoplasmic region	cellular_component	Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.
GO:0099569	presynaptic cytoskeleton	cellular_component	The portion of the cytoskeleton contained within the presynapse.
GO:0099571	postsynaptic cytoskeleton	cellular_component	The portion of the cytoskeleton contained within the postsynapse.
GO:0099572	postsynaptic specialization	cellular_component	A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
GO:0099573	glutamatergic postsynaptic density	cellular_component	The post-synaptic specialization of a glutamatergic excitatory synapse.
GO:0099574	regulation of protein catabolic process at synapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating protein degradation at the synapse.
GO:0099575	regulation of protein catabolic process at presynapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.
GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.
GO:0099577	regulation of translation at presynapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.
GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	biological_process	Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.
GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	molecular_function	A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential.
GO:0099580	monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential	molecular_function	Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
GO:0099581	ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential	molecular_function	Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
GO:0099582	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration	molecular_function	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.
GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.
GO:0099585	release of sequestered calcium ion into presynaptic cytosol	biological_process	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.
GO:0099586	release of sequestered calcium ion into postsynaptic cytosol	biological_process	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.
GO:0099587	inorganic ion import across plasma membrane	biological_process	The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:0099588	positive regulation of postsynaptic cytosolic calcium concentration	biological_process	Any process that increases the concentration of calcium ions in the postsynaptic cytosol.
GO:0099589	serotonin receptor activity	molecular_function	Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
GO:0099590	neurotransmitter receptor internalization	biological_process	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.
GO:0099592	endocytosed synaptic vesicle processing via endosome	biological_process	The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
GO:0099593	endocytosed synaptic vesicle to endosome fusion	biological_process	Fusion of an endocytosed synaptic vesicle with an endosome.
GO:0099601	regulation of neurotransmitter receptor activity	biological_process	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
GO:0099602	neurotransmitter receptor regulator activity	molecular_function	A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
GO:0099604	ligand-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0099605	regulation of action potential firing rate	biological_process	Any process that regulates the frequency of action potentials in a spike train.
GO:0099606	microtubule plus-end directed mitotic chromosome migration	biological_process	The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.
GO:0099607	lateral attachment of mitotic spindle microtubules to kinetochore	biological_process	The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).
GO:0099608	regulation of action potential firing pattern	biological_process	Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.
GO:0099609	microtubule lateral binding	molecular_function	Binding to the side of a microtubule.
GO:0099610	action potential initiation	biological_process	The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.
GO:0099611	regulation of action potential firing threshold	biological_process	Any process that regulates the potential at which an axon potential is triggered.
GO:0099612	protein localization to axon	biological_process	A process in which a protein is transported to or maintained in a location within an axon.
GO:0099613	protein localization to cell wall	biological_process	The process of directing proteins towards the cell-wall.
GO:0099614	protein localization to spore cell wall	biological_process	A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.
GO:0099615	(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.
GO:0099616	extrinsic component of matrix side of mitochondrial inner membrane	cellular_component	The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0099617	matrix side of mitochondrial inner membrane	cellular_component	The side (leaflet) of the mitochondrial inner membrane that faces the matrix.
GO:0099618	UDP-glucuronic acid dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.
GO:0099619	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity	molecular_function	Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
GO:0099620	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	molecular_function	Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate.
GO:0099621	undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity	molecular_function	Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.
GO:0099622	cardiac muscle cell membrane repolarization	biological_process	The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
GO:0099623	regulation of cardiac muscle cell membrane repolarization	biological_process	Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.
GO:0099624	atrial cardiac muscle cell membrane repolarization	biological_process	The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
GO:0099625	ventricular cardiac muscle cell membrane repolarization	biological_process	The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	molecular_function	Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.
GO:0099627	neurotransmitter receptor cycle	biological_process	The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).
GO:0099628	neurotransmitter receptor diffusion trapping	biological_process	The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.
GO:0099629	postsynaptic specialization of symmetric synapse	cellular_component	A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.
GO:0099630	postsynaptic neurotransmitter receptor cycle	biological_process	The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
GO:0099631	postsynaptic endocytic zone cytoplasmic component	cellular_component	The cytoplasmic component of the postsynaptic endocytic zone.
GO:0099632	protein transport within plasma membrane	biological_process	A process in which protein is transported from one region of the plasma membrane to another.
GO:0099633	protein localization to postsynaptic specialization membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).
GO:0099634	postsynaptic specialization membrane	cellular_component	The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
GO:0099635	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	molecular_function	Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.
GO:0099636	cytoplasmic streaming	biological_process	The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.
GO:0099637	neurotransmitter receptor transport	biological_process	The directed movement of neurotransmitter receptors.
GO:0099638	endosome to plasma membrane protein transport	biological_process	The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	biological_process	The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.
GO:0099640	axo-dendritic protein transport	biological_process	The directed movement of proteins along microtubules in neuron projections.
GO:0099641	anterograde axonal protein transport	biological_process	The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.
GO:0099642	retrograde axonal protein transport	biological_process	The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.
GO:0099643	signal release from synapse	biological_process	Any signal release from a synapse.
GO:0099644	protein localization to presynaptic membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	biological_process	A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
GO:0099646	neurotransmitter receptor transport, plasma membrane to endosome	biological_process	Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.
GO:0099703	induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration	biological_process	The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.
GO:0099738	cell cortex region	cellular_component	The complete extent of cell cortex that underlies some some region of the plasma membrane.
GO:0100001	regulation of skeletal muscle contraction by action potential	biological_process	Any action potential process that regulates skeletal muscle contraction.
GO:0100008	regulation of fever generation by prostaglandin biosynthetic process	biological_process	Any prostaglandin biosynthetic process process that regulates fever generation.
GO:0100009	regulation of fever generation by prostaglandin secretion	biological_process	Any prostaglandin secretion process that regulates fever generation.
GO:0100010	positive regulation of fever generation by prostaglandin biosynthetic process	biological_process	Any prostaglandin biosynthetic process process that positively_regulates fever generation.
GO:0100011	positive regulation of fever generation by prostaglandin secretion	biological_process	Any prostaglandin secretion process that positively_regulates fever generation.
GO:0100012	regulation of heart induction by canonical Wnt signaling pathway	biological_process	Any canonical Wnt signaling pathway process that regulates heart induction.
GO:0100067	positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway	biological_process	Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation.
GO:0101002	ficolin-1-rich granule	cellular_component	Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.
GO:0101003	ficolin-1-rich granule membrane	cellular_component	The lipid bilayer surrounding a ficolin-1-rich granule.
GO:0101004	cytolytic granule membrane	cellular_component	The lipid bilayer surrounding the cytolytic granule.
GO:0101005	deubiquitinase activity	molecular_function	An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
GO:0101006	protein histidine phosphatase activity	molecular_function	Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.
GO:0101010	pulmonary blood vessel remodeling	biological_process	The reorganization or renovation of existing pulmonary blood vessels.
GO:0101013	mechanosensitive voltage-gated sodium channel activity	molecular_function	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0101014	[isocitrate dehydrogenase (NADP+)] phosphatase activity	molecular_function	Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.
GO:0101016	FMN-binding domain binding	molecular_function	Binding to the FMN-binding domain of a protein.
GO:0101017	regulation of mitotic DNA replication initiation from late origin	biological_process	Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.
GO:0101018	negative regulation of mitotic DNA replication initiation from late origin	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.
GO:0101019	nucleolar exosome (RNase complex)	cellular_component	A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
GO:0101020	estrogen 16-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.
GO:0101021	estrogen 2-hydroxylase activity	molecular_function	Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.
GO:0101023	vascular endothelial cell proliferation	biological_process	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.
GO:0101024	mitotic nuclear membrane organization	biological_process	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.
GO:0101025	nuclear membrane biogenesis	biological_process	The process in which a nuclear membrane is synthesized, aggregates, and bonds together.
GO:0101026	mitotic nuclear membrane biogenesis	biological_process	A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.
GO:0101027	optical nerve axon regeneration	biological_process	The regrowth of axons of the optical nerve following their loss or damage.
GO:0101030	tRNA-guanine transglycosylation	biological_process	The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
GO:0101031	protein folding chaperone complex	cellular_component	A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
GO:0102001	isoleucine N-monooxygenase (oxime forming) activity	molecular_function	Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.
GO:0102002	valine N-monooxygenase (oxime forming) activity	molecular_function	Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.
GO:0102003	Delta8-sphingolipid desaturase activity	molecular_function	Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor.
GO:0102004	2-octaprenyl-6-hydroxyphenol methylase activity	molecular_function	Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.
GO:0102006	4-methyl-2-oxopentanoate dehydrogenase activity	molecular_function	Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-).
GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity	molecular_function	Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.
GO:0102009	proline dipeptidase activity	molecular_function	Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.
GO:0102013	ATPase-coupled L-glutamate tranmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in).
GO:0102014	beta-D-galactose-importing ATPase activity	molecular_function	Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+.
GO:0102025	ABC-type thiosulfate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).
GO:0102027	S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity	molecular_function	Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine.
GO:0102028	cystathionine gamma-synthase activity (acts on O-phosphohomoserine)	molecular_function	Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate.
GO:0102029	D-lactate dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.
GO:0102030	dTDP-L-rhamnose synthetase activity	molecular_function	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+.
GO:0102031	4-acetamido-4,6-dideoxy-D-galactose transferase activity	molecular_function	Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP.
GO:0102033	long-chain fatty acid omega-hydroxylase activity	molecular_function	Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0102035	isobutyryl-CoA:FAD oxidoreductase activity	molecular_function	Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2.
GO:0102036	methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity	molecular_function	Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein].
GO:0102037	4-nitrotoluene monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O.
GO:0102038	4-nitrobenzyl alcohol oxidase activity	molecular_function	Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide.
GO:0102039	NADH-dependent peroxiredoxin activity	molecular_function	Catalysis of the reaction: a hydroperoxide + H+ + NADH = an alcohol + H2O + NAD+.
GO:0102040	fumarate reductase (menaquinone)	molecular_function	Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone.
GO:0102041	7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase	molecular_function	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid.
GO:0102042	dehydroquinate synthase activity	molecular_function	Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+.
GO:0102043	isopentenyl phosphate kinase activity	molecular_function	Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-).
GO:0102044	3-chlorobenzoate-4,5-oxygenase activity	molecular_function	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.
GO:0102045	3-chlorobenzoate-3,4-oxygenase activity	molecular_function	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.
GO:0102046	3,4-dichlorobenzoate-4,5-oxygenase activity	molecular_function	Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.
GO:0102047	indole-3-acetyl-glycine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.
GO:0102048	indole-3-acetyl-isoleucine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid.
GO:0102049	indole-3-acetyl-methionine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid.
GO:0102050	indole-3-acetyl-tyrosine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid.
GO:0102051	indole-3-acetyl-tryptophan synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid.
GO:0102052	indole-3-acetyl-proline synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid.
GO:0102053	(-)-jasmonoyl-isoleucine synthetase activity	molecular_function	Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid.
GO:0102054	maleylpyruvate hydrolase activity	molecular_function	Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate.
GO:0102055	12-hydroxyjasmonate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate.
GO:0102056	11-hydroxyjasmonate sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate.
GO:0102057	jasmonoyl-valine synthetase activity	molecular_function	Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine.
GO:0102058	jasmonoyl-leucine synthetase activity	molecular_function	Catalysis of the reaction: L-leucine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine.
GO:0102059	2-cis,6-cis-farnesyl pyrophosphate synthase activity	molecular_function	Catalysis of the reaction: dimethylallyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphate + (2Z,6Z)-farnesyl diphosphate.
GO:0102060	endo-alpha-bergamotene synthase activity	molecular_function	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid.
GO:0102061	endo-beta-bergamotene synthase activity	molecular_function	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid.
GO:0102062	alpha-santalene synthase activity	molecular_function	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid.
GO:0102063	beta-curcumene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene.
GO:0102064	gamma-curcumene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid.
GO:0102065	patchoulene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene.
GO:0102066	alpha-patchoulene synthase activityy	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene.
GO:0102067	geranylgeranyl diphosphate reductase activity	molecular_function	Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+.
GO:0102068	alpha-humulene 10-hydroxylase activity	molecular_function	Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O.
GO:0102069	zerumbone synthase activity	molecular_function	Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+.
GO:0102070	18-hydroxyoleate peroxygenase activity	molecular_function	Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol.
GO:0102071	9,10-epoxy-18-hydroxystearate hydrolase activity	molecular_function	Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate.
GO:0102076	beta,beta-carotene-9',10'-cleaving oxygenase activity	molecular_function	Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone.
GO:0102080	phenylacetyl-coenzyme A:glycine N-acyltransferase activity	molecular_function	Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A.
GO:0102081	homotaurine:2-oxoglutarate aminotransferase activity	molecular_function	Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-).
GO:0102082	demethylrebeccamycin--D-glucose O-methyltransferase activity	molecular_function	Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine.
GO:0102083	7,8-dihydromonapterin aldolase activity	molecular_function	Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.
GO:0102084	L-dopa O-methyltransferase activity	molecular_function	Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+.
GO:0102085	N-(4-aminobenzoyl)-L-glutamate synthetase activity	molecular_function	Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid.
GO:0102086	N-vanillate-L-glutamate synthetase activity	molecular_function	Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid.
GO:0102087	N-benzoyl-L-glutamate synthetase activity	molecular_function	Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid.
GO:0102088	N-(4-hydroxybenzoyl)-L-glutamate synthetase activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid.
GO:0102089	dehydroscoulerine synthase activity	molecular_function	Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+.
GO:0102090	adrenaline O-methyltransferase activity	molecular_function	Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine <=> metanephrine + S-adenosyl-L-homocysteine + H+.
GO:0102091	phosphatidylinositol-5-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = an 1-phosphatidyl-1D-myo-inositol + phosphate.
GO:0102093	acrylate:acyl-coA CoA transferase activity	molecular_function	Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+.
GO:0102094	S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a demethylmenaquinol <=> S-adenosyl-L-homocysteine + H+ + a menaquinol.
GO:0102096	decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.
GO:0102097	(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O.
GO:0102098	D-galacturonate reductase activity	molecular_function	Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.
GO:0102099	FAD-dependent urate hydroxylase activity	molecular_function	Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O.
GO:0102100	mycothiol-arsenate ligase activity	molecular_function	Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O.
GO:0102102	homocarnosine synthase activity	molecular_function	Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate.
GO:0102103	demethoxycurcumin synthase	molecular_function	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.
GO:0102104	demethoxycurcumin synthase activity	molecular_function	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide.
GO:0102105	demethoxycurcumin synthase activity from feruloylacetyl-CoA	molecular_function	Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide.
GO:0102106	curcumin synthase activity	molecular_function	Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide.
GO:0102109	tricaffeoyl spermidine O-methyltransferase activity	molecular_function	Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.
GO:0102111	gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide.
GO:0102115	peptidoglycan asparagine synthase activity	molecular_function	Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid.
GO:0102117	gibberellin A9 carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine.
GO:0102118	gibberellin A4 carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.
GO:0102119	gibberellin A20 carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine.
GO:0102121	ceramidase activity	molecular_function	Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid.
GO:0102122	gibberellin A34 carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine.
GO:0102123	gibberellin A4 16alpha,17 epoxidase activity	molecular_function	Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P).
GO:0102124	gibberellin A12 16alpha,17 epoxidase activity	molecular_function	Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P).
GO:0102125	gibberellin A9 16alpha,17 epoxidase activity	molecular_function	Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P).
GO:0102126	coniferyl aldehyde 5-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O.
GO:0102127	8-oxoguanine deaminase activity	molecular_function	Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.
GO:0102128	chalcone synthase activity	molecular_function	Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide.
GO:0102130	malonyl-CoA methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester.
GO:0102133	limonene hydroxylase activity	molecular_function	Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O.
GO:0102134	(22S)-22-hydroxy-campesterol C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O.
GO:0102135	(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.
GO:0102136	3-epi-6-deoxocathasterone C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + reduced (NADPH-hemoprotein reducdtase) + O2 = 6=deoxotyphasterol + oxidized (NADPH-hemoprotein reductase) + H2O.
GO:0102137	7-oxateasterone synthase activity	molecular_function	Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O.
GO:0102138	7-oxatyphasterol synthase activity	molecular_function	Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O.
GO:0102139	2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity	molecular_function	Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.
GO:0102140	heparan sulfate N-deacetylase activity	molecular_function	Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine.
GO:0102141	[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate.
GO:0102142	[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity	molecular_function	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate.
GO:0102143	carboxynorspermidine dehydrogenase I activity	molecular_function	Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+.
GO:0102144	carboxyspermidine dehydrogenase II activity	molecular_function	Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+.
GO:0102145	(3R)-(E)-nerolidol synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid.
GO:0102146	tricetin O-methytransferase activity	molecular_function	Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine.
GO:0102147	3'-O-methyltricetin O methyl transferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin.
GO:0102148	N-acetyl-beta-D-galactosaminidase activity	molecular_function	Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan.
GO:0102149	farnesylcysteine lyase activity	molecular_function	Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide.
GO:0102150	3-oxo-myristoyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+.
GO:0102151	3-oxo-myristate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide.
GO:0102152	Delta12-linoleate epoxygenase activity	molecular_function	Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O.
GO:0102154	8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+.
GO:0102155	S-sulfolactate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+.
GO:0102156	2,5-DHBA UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+.
GO:0102157	(R)-sulfopropanediol 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.
GO:0102158	very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity	molecular_function	Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA.
GO:0102159	baicalein 7-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin.
GO:0102160	cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP.
GO:0102161	copal-8-ol diphosphate synthase activity	molecular_function	Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.
GO:0102162	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity	molecular_function	Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial.
GO:0102163	3-hydroxyacyl-CoA-acyl carrier protein transferase activity	molecular_function	Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein].
GO:0102164	2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity	molecular_function	Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O.
GO:0102165	(Z)-3-hexen-1-ol acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A.
GO:0102166	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity	molecular_function	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine.
GO:0102167	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity	molecular_function	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine.
GO:0102168	5-methyl-phenazine-1-carboxylate N-methyltransferase activity	molecular_function	Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine.
GO:0102169	pyocyanin hydroxylase activity	molecular_function	Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ = pyocyanin + NAD + carbon dioxide + H2O.
GO:0102170	5-epi-aristolochene-1,3-dihydroxylase activity	molecular_function	Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O.
GO:0102171	DMNT synthase activity	molecular_function	Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O.
GO:0102172	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.
GO:0102173	24-methylenecycloartanol 4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.
GO:0102174	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.
GO:0102175	3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity	molecular_function	Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD+ = a 3-oxosteroid + CO2 + NADH.
GO:0102177	24-methylenelophenol methyl oxidase activity	molecular_function	Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.
GO:0102178	4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.
GO:0102179	24-ethylidenelophenol 4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.
GO:0102180	4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O.
GO:0102181	4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.
GO:0102182	4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	molecular_function	Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide.
GO:0102184	cycloartenol 4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O.
GO:0102185	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O.
GO:0102186	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O.
GO:0102188	4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.
GO:0102189	4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O.
GO:0102190	4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	molecular_function	Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.
GO:0102191	4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	molecular_function	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide.
GO:0102193	protein-ribulosamine 3-kinase activity	molecular_function	Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine.
GO:0102194	protein-fructosamine 3-kinase activity	molecular_function	Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine.
GO:0102195	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity	molecular_function	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+.
GO:0102196	cortisol dehydrogenase activity	molecular_function	Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+.
GO:0102197	vinylacetate caboxylester hydrolase activity	molecular_function	Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate.
GO:0102198	L-idonate 5-dehydrogenase activity (NAD-dependent)	molecular_function	Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+.
GO:0102199	nitric oxide reductase activity (NAD(P)H-dependent) activity	molecular_function	Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H.
GO:0102200	N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity	molecular_function	Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate.
GO:0102201	(+)-2-epi-prezizaene synthase activity	molecular_function	Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid.
GO:0102202	soladodine glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+.
GO:0102203	brassicasterol glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+.
GO:0102205	cholesterol alpha-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+.
GO:0102208	2-polyprenyl-6-hydroxyphenol methylase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
GO:0102209	trans-permethrin hydrolase activity	molecular_function	Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate.
GO:0102210	rhamnogalacturonan endolyase activity	molecular_function	Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide].
GO:0102211	unsaturated rhamnogalacturonyl hydrolase activity	molecular_function	Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose.
GO:0102212	unsaturated chondroitin disaccharide hydrolase activity	molecular_function	Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate.
GO:0102213	in-chain hydroxy fatty acyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA.
GO:0102214	omega-hydroxy fatty acyl-CoA synthetase activity	molecular_function	Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA.
GO:0102215	thiocyanate methyltransferase activity	molecular_function	Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine <=> methyl thiocyanate + S-adenosyl-L-homocysteine.
GO:0102216	maltodextrin water dikinase	molecular_function	Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin.
GO:0102217	6-phosphoglucan, water dikinase activity	molecular_function	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.
GO:0102218	starch, H2O dikinase activity	molecular_function	Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin.
GO:0102219	phosphogluco-amylopectin water dikinase activity	molecular_function	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.
GO:0102220	hydrogenase activity (NAD+, ferredoxin)	molecular_function	Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin.
GO:0102223	4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)	molecular_function	Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD = 4,4'-diapolycopene + 4 FADH2. This reaction consists of three successive dehydrogenations that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene, 4,4'-diapo-zeta-carotene and 4,4'-diapolycopene as intermediates, and 4,4'-diapolycopene as the end product.
GO:0102224	GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity	molecular_function	Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.
GO:0102229	amylopectin maltohydrolase activity	molecular_function	Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose.
GO:0102232	acrolein reductase activity	molecular_function	Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP.
GO:0102233	crotonaldehyde redutase activity	molecular_function	Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.
GO:0102234	but-1-en-3-one reductase activity	molecular_function	Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP.
GO:0102235	1-penten-3-one reductase activity	molecular_function	Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP.
GO:0102236	trans-4-hexen-3-one reductase activity	molecular_function	Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP.
GO:0102237	ATP:farnesol kinase activity	molecular_function	Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+.
GO:0102238	geraniol kinase activity (ATP-dependent) activity	molecular_function	Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+.
GO:0102240	soyasapogenol B glucuronide galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III.
GO:0102241	soyasaponin III rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I.
GO:0102243	ATP:geranylgeraniol phosphotransferase activity	molecular_function	Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP.
GO:0102244	3-aminopropanal dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine + NADH.
GO:0102245	lupan-3beta,20-diol synthase activity	molecular_function	Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O.
GO:0102246	6-amino-6-deoxyfutalosine hydrolase activity	molecular_function	Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine.
GO:0102247	malonyl-malonyl acyl carrier protein-condensing enzyme activity	molecular_function	Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein].
GO:0102248	diacylglycerol transacylase activity	molecular_function	Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride.
GO:0102249	phosphatidylcholine:diacylglycerol cholinephosphotransferase activity	molecular_function	Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine.
GO:0102250	linear malto-oligosaccharide phosphorylase activity	molecular_function	Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide.
GO:0102251	all-trans-beta-apo-10'-carotenal cleavage oxygenase activity	molecular_function	Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial.
GO:0102252	cellulose 1,4-beta-cellobiosidase activity (reducing end)	molecular_function	Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains.
GO:0102253	neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity	molecular_function	Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.
GO:0102254	neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity	molecular_function	Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose.
GO:0102255	neo-lambda-carrahexaose hydrolase activity	molecular_function	Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose.
GO:0102256	neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity	molecular_function	Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose.
GO:0102257	1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity	molecular_function	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+.
GO:0102258	1,3-diacylglycerol acylhydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid.
GO:0102259	1,2-diacylglycerol acylhydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid.
GO:0102261	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity	molecular_function	Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420.
GO:0102262	tRNA-dihydrouridine16 synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) = H+ + a uracil16 in tRNA + NAD(P)H.
GO:0102263	tRNA-dihydrouridine17 synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) = H+ + a uracil17 in tRNA + NAD(P)H.
GO:0102264	tRNA-dihydrouridine20 synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) = H+ + a uracil20 in tRNA + NAD(P)H.
GO:0102265	tRNA-dihydrouridine47 synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) = H+ + a uracil47 in tRNA + NAD(P)H.
GO:0102266	tRNA-dihydrouridine20a synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) = H+ + a uracil20a in tRNA + NAD(P)H.
GO:0102267	tRNA-dihydrouridine20b synthase activity	molecular_function	Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) = H+ + a uracil20b in tRNA + NAD(P)H.
GO:0102272	homophytochelatin synthase activity (polymer-forming)	molecular_function	Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine.
GO:0102273	homophytochelatin synthase (dimmer forming) activity	molecular_function	Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine.
GO:0102274	glutathione S-conjugate carboxypeptidase activity	molecular_function	Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate.
GO:0102275	cysteine-S-conjugate N-malonyl transferase activity	molecular_function	Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate.
GO:0102276	2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O.
GO:0102277	2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity	molecular_function	Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine.
GO:0102278	N,N'-diacetylchitobiose synthase activity	molecular_function	Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose.
GO:0102279	lecithin:11-cis retinol acyltransferase activity	molecular_function	Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine.
GO:0102280	choline monooxygenase activity (NADP-dependent)	molecular_function	Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+.
GO:0102281	formylaminopyrimidine deformylase activity	molecular_function	Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate.
GO:0102285	1-deoxy-11-oxopentalenate oxygenase activity	molecular_function	Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP.
GO:0102286	ornithine N-delta-acetyltransferase activity	molecular_function	Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine.
GO:0102287	4-coumaroylhexanoylmethane synthase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.
GO:0102289	beta-amyrin 11-oxidase activity	molecular_function	Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP.
GO:0102290	beta-amyrin monooxygenase activity	molecular_function	Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP.
GO:0102291	11alpha-hydroxy-beta-amyrin dehydrogenase activity	molecular_function	Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP.
GO:0102292	30-hydroxy-beta-amyrin 11-hydroxylase activity	molecular_function	Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP.
GO:0102293	pheophytinase b activity	molecular_function	Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol.
GO:0102294	cholesterol dehydrogenase activity	molecular_function	Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+.
GO:0102295	4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.
GO:0102296	4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity	molecular_function	Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.
GO:0102297	selenate adenylyltransferase activity	molecular_function	Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid.
GO:0102298	selenocystathione synthase activity	molecular_function	Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine.
GO:0102299	linolenate 9R-lipoxygenase activity	molecular_function	Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate.
GO:0102300	linoleate 9R-lipoxygenase activity	molecular_function	Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE.
GO:0102301	gamma-linolenate elongase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide.
GO:0102302	mycinamicin VI 2''-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI <=> S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+.
GO:0102303	resveratrol 3,5-O-dimethyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine + pterostilbene + 2 H+.
GO:0102304	sesquithujene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid.
GO:0102305	(13E)-labda-7,13-dien-15-ol synthase activity	molecular_function	Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid.
GO:0102306	benzil reductase [(S)-benzoin-forming] activity	molecular_function	Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+.
GO:0102307	erythromycin C 3''-o-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+.
GO:0102308	erythromycin D 3''-o-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+.
GO:0102310	dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity	molecular_function	Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H.
GO:0102311	8-hydroxygeraniol dehydrogenase activity	molecular_function	Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+.
GO:0102312	4-coumaroyl 2'-hydroxylase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide.
GO:0102313	1,8-cineole synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid.
GO:0102317	4-methylaminobutyrate oxidase (demethylating) activity	molecular_function	Catalysis of the reaction: 4-(methylamino)butyric acid + O2 + H2O <=> gamma-aminobutyric acid + formaldehyde + hydrogen peroxide.
GO:0102318	2-deoxystreptamine glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+.
GO:0102319	2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-).
GO:0102320	1,8-cineole 2-exo-monooxygenase activity	molecular_function	Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O.
GO:0102321	2,2'-hydroxybiphenyl monooxygenase activity	molecular_function	Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD.
GO:0102322	2-propylphenol monooxygenase activity	molecular_function	Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD.
GO:0102323	2-isopropylphenol monooxygenase activity	molecular_function	Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD.
GO:0102324	2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+.
GO:0102325	2,2',3-trihydroxybiphenyl monooxygenase activity	molecular_function	Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O.
GO:0102326	2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+.
GO:0102327	3-oxoacyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid.
GO:0102328	3-oxoacid decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone.
GO:0102330	palmitoyl-[acp] elongase/decarboxylase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].
GO:0102331	heptadecanoyl-[acp] elongase/decarboxylase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].
GO:0102332	fatty-acyl-[acp] elongase/decarboxylase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor.
GO:0102333	stearoyl-[acp] elongase/decarboxylase activity	molecular_function	Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].
GO:0102334	N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity	molecular_function	Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP.
GO:0102335	N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity	molecular_function	Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.
GO:0102351	gamma-aminobutyrate transaminase (glyoxylate dependent) activity	molecular_function	Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine.
GO:0102352	phosphatidate kinase activity	molecular_function	Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate.
GO:0102354	11-cis-retinol dehydrogenase activity	molecular_function	Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+.
GO:0102355	2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity	molecular_function	Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+.
GO:0102356	isoitalicene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene.
GO:0102357	mithramycin dehydrogenase activity	molecular_function	Catalysis of the reaction: mithramycin + NADP = mithramycin DK + NADPH + H+.
GO:0102358	daphnetin-8-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+.
GO:0102359	daphnetin 4-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+.
GO:0102360	daphnetin 3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+.
GO:0102361	esculetin 4-O-beta-glucosyltransferase activity	molecular_function	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+.
GO:0102362	esculetin 3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+.
GO:0102363	isoscopoletin-O-methyltransferase activity	molecular_function	Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+.
GO:0102365	taxusin 2-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O.
GO:0102366	7-beta-hydroxytaxusin 2-alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O.
GO:0102367	2-alpha-hydroxytaxusin 7-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O.
GO:0102368	beta-amyrin 30-monooxygenase activity	molecular_function	Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O.
GO:0102369	11alpha-30-dihydroxy beta-amyrin dehydrogenase activity	molecular_function	Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O.
GO:0102370	lupeol 28-monooxygenase activity	molecular_function	Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O.
GO:0102371	betulin dehydrogenase activity	molecular_function	Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O.
GO:0102372	alpha-amyrin 28-monooxygenase activity	molecular_function	Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O.
GO:0102373	uvaol dehydrogenase activity	molecular_function	Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O.
GO:0102374	ursolic aldehyde 28-monooxygenase activity	molecular_function	Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O.
GO:0102375	11-oxo-beta-amyrin 30-oxidase activity	molecular_function	Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O.
GO:0102376	lupeol 28-oxidase activity	molecular_function	Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O.
GO:0102377	steviol 13-O glucosyltransferase activity	molecular_function	Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+.
GO:0102378	steviolmonoside glucosyltransferase activity	molecular_function	Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+.
GO:0102379	steviolbioside glucosyltransferase activity (stevioside forming)	molecular_function	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+.
GO:0102380	steviolbioside glucosyltransferase activity (rebaudioside B forming)	molecular_function	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+.
GO:0102381	stevioside glucosyltransferase activity (rebaudioside A forming)	molecular_function	Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+.
GO:0102382	rebaudioside B glucosyltransferase activity	molecular_function	Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+.
GO:0102383	steviol 19-O glucosyltransferase activity	molecular_function	Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+.
GO:0102384	19-O-beta-glucopyranosyl-steviol glucosyltransferase activity	molecular_function	Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+.
GO:0102385	patchoulol synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid.
GO:0102386	phenylacetaldehyde reductase activity	molecular_function	Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+.
GO:0102387	2-phenylethanol acetyltransferase activity	molecular_function	Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A.
GO:0102388	UDP-N,N'-diacetylbacillosamine 2-epimerase activity	molecular_function	Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+.
GO:0102389	polyprenol reductase activity	molecular_function	Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol.
GO:0102390	mycophenolic acid acyl-glucuronide esterase activity	molecular_function	Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate.
GO:0102391	decanoate-CoA ligase activity	molecular_function	Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA.
GO:0102392	decanoate-[HmqF protein] ligase activity	molecular_function	Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein.
GO:0102393	decanoyl-[acp] 2-dehydrogenase activity	molecular_function	Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein = FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF.
GO:0102394	4-hydroxy-L-isoleucine dehydrogenase activity	molecular_function	Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD = (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+.
GO:0102395	9-cis-beta-carotene 9',10'-cleavage oxygenase activity	molecular_function	Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone.
GO:0102396	9-cis-10'-apo-beta-carotenal cleavage oxygenase activity	molecular_function	Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal.
GO:0102398	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.
GO:0102399	dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.
GO:0102400	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+.
GO:0102402	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	molecular_function	Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose.
GO:0102404	linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	molecular_function	Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool.
GO:0102405	(+)-taxifolin 5'-hydroxylase activity	molecular_function	Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O.
GO:0102406	omega-hydroxypalmitate O-sinapoyl transferase activity	molecular_function	Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate.
GO:0102410	quercetin-4',3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).
GO:0102411	quercetin-3,4'-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).
GO:0102412	valerena-4,7(11)-diene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid.
GO:0102413	6-O-methyl-deacetylisoipecoside beta-glucosidase activity	molecular_function	Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose.
GO:0102414	quercetin-3-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP.
GO:0102415	quercetin gentiobioside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+.
GO:0102416	quercetin gentiotrioside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+.
GO:0102417	apigenin-7-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+.
GO:0102418	luteolin-7-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+.
GO:0102420	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	molecular_function	Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.
GO:0102421	curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+.
GO:0102422	curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+.
GO:0102423	(+)-sesaminol 2-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+.
GO:0102424	sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+.
GO:0102425	myricetin 3-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP.
GO:0102426	myricetin-3-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+.
GO:0102427	allocryptopine 6-hydroxylase activity	molecular_function	Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O.
GO:0102428	kaempferol-3-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP.
GO:0102429	genistein-3-O-glucoside 1,6-glucosyltransferase activity	molecular_function	Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+.
GO:0102431	acyl-lipid omega-(9-4) desaturase activity	molecular_function	Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid) and add a fourth double bond (a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid).
GO:0102432	quercetin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine.
GO:0102433	phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity	molecular_function	Catalysis of the reaction: L-phenylalanine + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine + a 10-formyltetrahydrofolate-4a-carbinolamine.
GO:0102434	pterin-4alpha-carbinolamine dehydratase activity	molecular_function	Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.
GO:0102435	myricetin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine.
GO:0102436	7-methylmyricetin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+.
GO:0102438	laricitrin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine.
GO:0102439	3',4',5'-trimethylmyricetin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+.
GO:0102440	3',4',5'-trimethylmyricetin 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+.
GO:0102441	syringetin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.
GO:0102442	syringetin 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.
GO:0102443	L-2-hydroxycarboxylate dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate.
GO:0102444	isorhamnetin 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.
GO:0102445	3-methylquercetin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.
GO:0102446	rhamnetin 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H+.
GO:0102447	rhamnetin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+.
GO:0102448	rhamnetin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> ombuin + S-adenosyl-L-homocysteine + H+.
GO:0102449	kaempferol 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine.
GO:0102450	kaempferide 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.
GO:0102451	kaempferide 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.
GO:0102452	bisdemethoxycurcumin synthase activity	molecular_function	Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.
GO:0102453	anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside].
GO:0102454	cyanidin 3-O-galactosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP.
GO:0102455	anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside.
GO:0102456	cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+.
GO:0102457	cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate.
GO:0102458	cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+.
GO:0102459	8-oxo-dADP diphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+.
GO:0102460	kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP.
GO:0102461	kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP.
GO:0102462	quercetin 3-sophoroside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+.
GO:0102463	quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+.
GO:0102464	zeaxanthin 2-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD.
GO:0102465	zeaxanthin 2,2'-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O.
GO:0102466	beta-carotene 2,2'-beta-hydroxylase activity	molecular_function	Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.
GO:0102467	scutellarein 7-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+.
GO:0102468	wogonin 7-O-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+.
GO:0102469	naringenin 2-hydroxylase activity	molecular_function	Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O.
GO:0102470	6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+.
GO:0102471	2-hydroxynaringenin-6C-glucoside dehydratase activity	molecular_function	Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O.
GO:0102472	eriodictyol 2-hydroxylase activity	molecular_function	Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O.
GO:0102473	eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity	molecular_function	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+.
GO:0102474	eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity	molecular_function	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+.
GO:0102475	2-hydroxyeriodictyol 6C-glucoside dehydratase activity	molecular_function	Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O.
GO:0102476	pinocembrin 2-hydroxylase activity	molecular_function	Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O.
GO:0102477	2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity	molecular_function	Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O.
GO:0102478	beta-L-arabinofuranosidase activity	molecular_function	Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose.
GO:0102479	quercetin 3-O-beta:-D-galactosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+.
GO:0102480	5-fluorocytosine deaminase activity	molecular_function	Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium.
GO:0102481	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity	molecular_function	Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+.
GO:0102482	5-deoxy-D-glucuronate isomerase activity	molecular_function	Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.
GO:0102483	scopolin beta-glucosidase activity	molecular_function	Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.
GO:0102484	esculetin glucosyltransferase activity	molecular_function	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+.
GO:0102493	wogonin 7-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+.
GO:0102494	GA20 2,3-desaturase activity	molecular_function	Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor.
GO:0102495	GA5 3beta-hydroxylase activity	molecular_function	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide.
GO:0102496	GA5 2,3 epoxidase activity	molecular_function	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide.
GO:0102497	scyllo-inositol dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+.
GO:0102498	maltose glucosidase activity	molecular_function	Catalysis of the reaction: H2O + maltose = 2 glucose.
GO:0102499	SHG alpha-glucan phosphorylase activity	molecular_function	Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan.
GO:0102500	beta-maltose 4-alpha-glucanotransferase activity	molecular_function	Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose.
GO:0102501	D-fructuronate reductase activity	molecular_function	Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate.
GO:0102502	ADP-glucose-starch glucosyltransferase activity	molecular_function	Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose.
GO:0102504	luteolinidin 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+.
GO:0102505	apigeninidin 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+.
GO:0102506	cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+.
GO:0102507	cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+.
GO:0102508	cyanidin 3,7-diglucoside glucosidase activity	molecular_function	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.
GO:0102509	cyanidin 3,5-diglucoside glucosidase activity	molecular_function	Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.
GO:0102510	pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+.
GO:0102511	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+.
GO:0102512	delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+.
GO:0102513	delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+.
GO:0102514	cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+.
GO:0102515	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+.
GO:0102516	delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.
GO:0102517	oleate 12-hydroxylase activity	molecular_function	Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O.
GO:0102518	(11Z)-eicosenoate 14-hydroxylase activity	molecular_function	Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O.
GO:0102520	L-threonine O-3-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate.
GO:0102521	tRNA-4-demethylwyosine synthase activity	molecular_function	Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe.
GO:0102522	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe.
GO:0102523	2-chloroacrylate reductase activity	molecular_function	Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+.
GO:0102524	tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe.
GO:0102525	2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity	molecular_function	Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide.
GO:0102526	8-demethylnovobiocic acid C8-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine + novobiocic acid + H+.
GO:0102527	8-demethylnovobiocate synthase activity	molecular_function	Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid.
GO:0102528	7,8,4'-trihydroxyflavone methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone.
GO:0102529	apigenin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + apigenin-7-olate <=> S-adenosyl-L-homocysteine + genkwanin.
GO:0102530	aclacinomycin T methylesterase activity	molecular_function	Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T + methanol + H+.
GO:0102531	ecdysteroid-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = hydrogenphosphate + an ecdysteroid.
GO:0102532	genkwanin 6-hydroxylase activity	molecular_function	Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP.
GO:0102533	genkwanin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine.
GO:0102534	apigenin-7,4'-dimethyl ether 6-hydroxylase activity	molecular_function	Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP.
GO:0102535	ladanein 6-O-methyltransferase activity	molecular_function	Catalysis of the reaction: ladanein + S-adenosyl-L-methionine <=> H+ + salvigenin + S-adenosyl-L-homocysteine.
GO:0102536	sakuranetin 6-hydroxylase activity	molecular_function	Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP.
GO:0102537	ecdysone-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate.
GO:0102538	UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.
GO:0102539	UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.
GO:0102540	D-mannose 6-phosphate 1-epimerase activity	molecular_function	Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate.
GO:0102541	D-galactose 6-phosphate 1-epimerase activity	molecular_function	Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate.
GO:0102542	aclacinomycin A methylesterase activity	molecular_function	Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+.
GO:0102543	epsilon-rhodomycinone methylesterase activity	molecular_function	Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+.
GO:0102544	ornaline synthase activity	molecular_function	Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O.
GO:0102545	phosphatidyl phospholipase B activity	molecular_function	Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate.
GO:0102546	mannosylglycerate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate.
GO:0102547	glucosylglycerate hydrolase activity	molecular_function	Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate.
GO:0102549	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+.
GO:0102550	2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+.
GO:0102551	homogentisate geranylgeranyl transferase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide.
GO:0102556	dammarenediol 12-hydroxylase activity	molecular_function	Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O.
GO:0102557	protopanaxadiol 6-hydroxylase activity	molecular_function	Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O.
GO:0102559	protein-(glutamine-N5) methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine.
GO:0102560	5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity	molecular_function	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+.
GO:0102561	D-ribose 2,5-bisphosphate 2-phosphohydrolase activity	molecular_function	Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate.
GO:0102562	hydroxyproline O-arbinofuranose transferase activity	molecular_function	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline.
GO:0102563	aurachin C monooxygenase activity	molecular_function	Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P).
GO:0102564	aurachin C epoxide hydrolase/isomerase activity	molecular_function	Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P).
GO:0102566	1-acyl dihydroxyacetone phosphate reductase activity	molecular_function	Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP.
GO:0102569	FR-33289 synthase activity	molecular_function	Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide.
GO:0102570	tyrosine:phenylpyruvate aminotransferase activity	molecular_function	Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine = L-phenylalanine + 3-(4-hydroxyphenyl)pyruvate.
GO:0102571	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity	molecular_function	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine).
GO:0102572	N-glutamylanilide hydrolase activity	molecular_function	Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+.
GO:0102573	aminodeoxyfutalosine synthase activity	molecular_function	Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O <=> aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+.
GO:0102574	3-oxo-myristoyl-ACP hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein].
GO:0102575	3-oxo-dodecanoyl-ACP hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein].
GO:0102576	3-oxo-palmitoyl-ACP hydrolase activity	molecular_function	Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein].
GO:0102577	3-oxo-palmitate decarboxylase activity	molecular_function	Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide.
GO:0102580	cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP.
GO:0102581	cyanidin 3-O-glucoside-p-coumaroyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A.
GO:0102582	cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.
GO:0102583	cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.
GO:0102584	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+.
GO:0102585	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A.
GO:0102586	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose.
GO:0102587	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+.
GO:0102588	cyanidin 3-O-glucoside 6''-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.
GO:0102589	cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A.
GO:0102590	delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+.
GO:0102591	delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.
GO:0102592	delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose.
GO:0102593	UDP-glucose: N-methylanthranilate glucosyltransferase activity	molecular_function	Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP.
GO:0102594	cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.
GO:0102595	cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity	molecular_function	Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose.
GO:0102596	cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity	molecular_function	Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O.
GO:0102597	3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity	molecular_function	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O.
GO:0102598	3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity	molecular_function	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O.
GO:0102599	cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity	molecular_function	Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P).
GO:0102600	cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity	molecular_function	Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).
GO:0102601	cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity	molecular_function	Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP.
GO:0102602	cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity	molecular_function	Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).
GO:0102603	12-demethyl-elloramycin C12a O-methyltransferase activity	molecular_function	Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine <=> elloramycin + S-adenosyl-L-homocysteine + H+.
GO:0102605	cyclooctat-9-en-5,7-diol C18-monooxygenase activity	molecular_function	Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP.
GO:0102606	octat-9-en-7-ol 5-monooxygenase activity	molecular_function	Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP.
GO:0102607	3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity	molecular_function	Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O.
GO:0102608	tetracenomycin B3 8-O-methyl transferase activity	molecular_function	Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine <=> tetracenomycin E + S-adenosyl-L-homocysteine + H+.
GO:0102610	(+)-secoisolariciresinol glucosyltransferase activity	molecular_function	Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+.
GO:0102611	(+)-secoisolariciresinol monoglucoside glucosyltransferase activity	molecular_function	Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+.
GO:0102612	syn-pimaradiene 6beta-hydroxylase activity	molecular_function	Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O.
GO:0102613	trimethyluric acid monooxygenase activity	molecular_function	Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.
GO:0102614	germacrene A acid 8beta-hydroxylase activity	molecular_function	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O.
GO:0102615	ent-cassadiene-C2-hydroxylase activity	molecular_function	Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O.
GO:0102620	3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity	molecular_function	Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O.
GO:0102621	emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity	molecular_function	Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O.
GO:0102622	linuron hydrolase activity	molecular_function	Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline.
GO:0102623	scutellarein 7-methyl ether 6-O-methyltransferase activity	molecular_function	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H+.
GO:0102624	scutellarein 7-methyl ether 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> ladanein + S-adenosyl-L-homocysteine + H+.
GO:0102625	cirsimaritin 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+.
GO:0102626	parthenolide synthase activity	molecular_function	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O.
GO:0102627	parthenolide 3beta-hydroxylase activity	molecular_function	Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O.
GO:0102628	costunolide 3beta-hydroxylase activity	molecular_function	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O.
GO:0102629	patuletin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: patuletin + S-adenosyl-L-methionine <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+.
GO:0102630	gossypetin 8-methyl ester 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+.
GO:0102631	caffeoylglucose 3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+.
GO:0102632	(S)-nandinine synthase activity	molecular_function	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-nandinine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.
GO:0102633	flaviolin monooxygenase activity	molecular_function	Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O.
GO:0102634	1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity	molecular_function	Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+.
GO:0102635	11-deoxycorticosterone reductase activity	molecular_function	Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD.
GO:0102637	5-aminolevulinate-CoA ligase activity	molecular_function	Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid.
GO:0102638	[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity	molecular_function	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid.
GO:0102639	paspalicine synthase activity	molecular_function	Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O.
GO:0102640	paspalinine synthase activity	molecular_function	Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O.
GO:0102641	(R)-lactaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+.
GO:0102643	scalarane-17alpha-19-diol synthase activity	molecular_function	Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.
GO:0102644	monocyclic sesterterpenediol synthase activity	molecular_function	Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O.
GO:0102645	17(E)-cheilanthenediol synthase activity	molecular_function	Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O.
GO:0102646	14betaH-scalarane-17alpha-19-diol synthase activity	molecular_function	Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.
GO:0102647	D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity	molecular_function	Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate.
GO:0102648	D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity	molecular_function	Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate.
GO:0102649	acetoacetyl-ACP synthase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide.
GO:0102650	cyclo-acetoacetyl-L-tryptophan synthetase activity	molecular_function	Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein].
GO:0102652	gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide.
GO:0102653	gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O.
GO:0102654	1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity	molecular_function	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102655	1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102656	1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102657	1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102658	2-oxo-5-methylthiopentanoate aminotransferase activity	molecular_function	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate.
GO:0102659	UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP.
GO:0102660	caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity	molecular_function	Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate.
GO:0102661	homogentisate solanyltransferase activity	molecular_function	Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid.
GO:0102663	gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O.
GO:0102664	indole-3-acetyl-leucine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-leucine + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP.
GO:0102665	indole-3-acetyl-glutamate synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid.
GO:0102666	indole-3-acetyl-beta-4-D-glucose hydrolase activity	molecular_function	Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.
GO:0102667	indole-3-acetyl-beta-1-D-glucose hydrolase activity	molecular_function	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.
GO:0102669	isoflavone-7-O-glucoside beta-glucosidase activity	molecular_function	Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose.
GO:0102670	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.
GO:0102671	6a-hydroxymaackiain-3-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine.
GO:0102672	fatty acid alpha-oxygenase activity	molecular_function	Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid.
GO:0102673	fatty aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid.
GO:0102676	avenasterol-desaturase activity	molecular_function	Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP.
GO:0102677	campesterol,NADPH:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP.
GO:0102678	22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	molecular_function	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH.
GO:0102679	(5alpha)-campestan-3-one hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP.
GO:0102680	campest-4-en-3-one hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP.
GO:0102681	isoamylase (maltodextrin-releasing) activity	molecular_function	Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin.
GO:0102682	N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity	molecular_function	Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate.
GO:0102684	L-phenylalanine N-monooxygenase activity	molecular_function	Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.
GO:0102685	UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP.
GO:0102686	UDP-glucose:trans-zeatin 9-N-glucosyltransferase	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-).
GO:0102687	UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP.
GO:0102688	dihydrozeatin UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP.
GO:0102689	UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.
GO:0102690	isopentenyladenine UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.
GO:0102691	UDP-glucose:benzyladenine 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP.
GO:0102692	benzyladenine UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP.
GO:0102693	UDP-glucose:kinetin 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP.
GO:0102694	kinetin UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP.
GO:0102695	UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP.
GO:0102696	cis-zeatin UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.
GO:0102697	trans-zeatin-O-glucoside UDP glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP.
GO:0102698	5-epi-aristolochene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid.
GO:0102699	2-methylpropionitrile hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O.
GO:0102700	alpha-thujene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid.
GO:0102701	tricyclene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid.
GO:0102702	2-carene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid.
GO:0102703	camphene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid.
GO:0102704	GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.
GO:0102705	serine decarboxylase activity	molecular_function	Catalysis of the reaction: H+ + L-serine <=> ethanolaminium(1+) + carbon dioxide.
GO:0102706	butein:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+.
GO:0102707	S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity	molecular_function	Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine.
GO:0102708	S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity	molecular_function	Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine.
GO:0102709	S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity	molecular_function	Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine.
GO:0102710	D-inositol-3-phosphate glycosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+.
GO:0102711	gibberellin A25,oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide.
GO:0102712	gibberellin A13,oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide.
GO:0102713	gibberellin A25 hydroxylase activity	molecular_function	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide.
GO:0102714	gibberellin A12,oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide.
GO:0102715	gibberellin A17,oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide.
GO:0102716	gibberellin A28,oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide.
GO:0102717	DIBOA-glucoside oxygenase activity	molecular_function	Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide.
GO:0102718	TRIBOA-glucoside methyltransferase activity	molecular_function	Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+.
GO:0102719	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity	molecular_function	Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine.
GO:0102720	acetyl-coenzyme A:acetyl alcohol acetyltransferase activity	molecular_function	Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A.
GO:0102721	ubiquinol:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone.
GO:0102723	UDP-glucose:curcumin glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+.
GO:0102724	UDP-glucose:curcumin monoglucoside glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP.
GO:0102725	24-methyldesmosterol reductase activity	molecular_function	Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP.
GO:0102726	DIMBOA glucoside beta-D-glucosidase activity	molecular_function	Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose.
GO:0102727	3beta-hydroxysteroid dehydrogenase activity	molecular_function	Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+.
GO:0102728	campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	molecular_function	Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH.
GO:0102729	6-oxocampestanol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP.
GO:0102730	cathasterone hydroxylase activity	molecular_function	Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor.
GO:0102731	D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity	molecular_function	Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP.
GO:0102732	myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity	molecular_function	Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP.
GO:0102733	typhasterol C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor.
GO:0102734	brassinolide synthase activity	molecular_function	Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O.
GO:0102735	trihydroxybenzophenone synthase activity	molecular_function	Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.
GO:0102737	p-coumaroyltriacetic acid synthase activity	molecular_function	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate.
GO:0102738	(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate.
GO:0102739	(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide.
GO:0102740	theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity	molecular_function	Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine.
GO:0102741	paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity	molecular_function	Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine.
GO:0102742	R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity	molecular_function	Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP.
GO:0102743	eriodictyol,NADPH:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O.
GO:0102744	all-trans-geranyl-geranyl diphosphate reductase activity	molecular_function	Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP.
GO:0102745	dihydrogeranylgeranyl-PP reductase activity	molecular_function	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP.
GO:0102746	tetrahydrogeranylgeranyl-PP reductase activity	molecular_function	Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP.
GO:0102747	chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity	molecular_function	Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid.
GO:0102748	geranylgeranyl-chlorophyll a reductase activity	molecular_function	Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP.
GO:0102749	dihydrogeranylgeranyl-chlorophyll a reductase activity	molecular_function	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP.
GO:0102750	tetrahydrogeranylgeranyl-chlorophyll a reductase activity	molecular_function	Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+.
GO:0102751	UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+.
GO:0102752	1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)	molecular_function	Catalysis of the reaction: a glucosylated glycogenin = a glycogen.
GO:0102753	chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity	molecular_function	Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid.
GO:0102754	chlorophyllide-b:phytyl-diphosphate phytyltransferase activity	molecular_function	Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid.
GO:0102755	gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity	molecular_function	Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide.
GO:0102757	NADPH phosphatase activity	molecular_function	Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.
GO:0102758	very-long-chain enoyl-CoA reductase activity	molecular_function	Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + NADP+ = a very-long-chain (2E)-enoyl-CoA + H+ + NADPH.
GO:0102759	campestanol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP.
GO:0102760	6-deoxocathasterone hydroxylase activity	molecular_function	Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor.
GO:0102761	eriodictyol 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine.
GO:0102762	eriodictyol 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine.
GO:0102763	phytyl-P kinase activity	molecular_function	Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate.
GO:0102764	6-deoxotyphasterol C-23 hydroxylase activity	molecular_function	Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor.
GO:0102765	UDP-D-apiose synthase activity	molecular_function	Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide.
GO:0102766	naringenin 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine <=> sakuranetin + S-adenosyl-L-homocysteine + H+.
GO:0102767	flavanone 4'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.
GO:0102768	anthocyanidin synthase activity	molecular_function	Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate.
GO:0102769	dihydroceramide glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine.
GO:0102770	inositol phosphorylceramide synthase activity	molecular_function	Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.
GO:0102771	sphingolipid very long chain fatty acid alpha-hydroxylase activity	molecular_function	Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide.
GO:0102772	sphingolipid long-chain base 4-hydroxylase activity	molecular_function	Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P).
GO:0102773	dihydroceramide kinase activity	molecular_function	Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate.
GO:0102774	p-coumaroyltriacetic acid lactone synthase activity	molecular_function	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.
GO:0102775	6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity	molecular_function	Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide.
GO:0102776	UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+.
GO:0102777	caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-).
GO:0102778	delta9-tetrahydrocannabinolate synthase activity	molecular_function	Catalysis of the reaction: cannabigerolate + O2 <=> delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide.
GO:0102779	cannabidiolate synthase activity	molecular_function	Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide.
GO:0102780	sitosterol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP.
GO:0102781	isofucosterol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP.
GO:0102782	cholestanol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP.
GO:0102783	beta-carotene oxygenase activity	molecular_function	Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.
GO:0102784	lutein oxygenase activity	molecular_function	Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.
GO:0102785	violaxanthin oxygenase activity	molecular_function	Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.
GO:0102786	stearoyl-[acp] desaturase activity	molecular_function	Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin.
GO:0102787	caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A.
GO:0102788	4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A.
GO:0102789	UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP.
GO:0102790	cyanidin 5,3-O-glycosyltransferase activity	molecular_function	Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP.
GO:0102791	sulfuretin synthase activity	molecular_function	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O.
GO:0102792	sinapaldehyde:NAD(P)+ oxidoreductase activity	molecular_function	Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH.
GO:0102793	soyasapogenol B glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate.
GO:0102794	cinnamaldehyde:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide.
GO:0102795	1-naphthaldehyde:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide.
GO:0102796	protocatechualdehyde:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide.
GO:0102799	glucosinolate glucohydrolase activity	molecular_function	Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides.
GO:0102800	caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A.
GO:0102801	anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity	molecular_function	Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A.
GO:0102802	thebaine 6-O-demethylase activity	molecular_function	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide.
GO:0102803	thebane O-demethylase activity	molecular_function	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide.
GO:0102804	oripavine 6-O-demethylase activity	molecular_function	Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide.
GO:0102805	codeine O-demethylase activity	molecular_function	Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide.
GO:0102806	4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A.
GO:0102807	cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+.
GO:0102808	pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP.
GO:0102809	delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP.
GO:0102810	glutarate-semialdehyde dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+.
GO:0102811	geraniol 10-hydroxylase activity	molecular_function	Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O.
GO:0102812	4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	molecular_function	Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A.
GO:0102813	UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+.
GO:0102814	caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A.
GO:0102815	caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A.
GO:0102816	UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.
GO:0102817	caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity	molecular_function	Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A.
GO:0102818	lycopene cleavage oxygenase activity	molecular_function	Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde.
GO:0102819	bixin aldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+.
GO:0102820	norbixin methyltransferase activity	molecular_function	Catalysis of the reaction: norbixin + S-adenosyl-L-methionine <=> bixin + S-adenosyl-L-homocysteine.
GO:0102821	bixin methyltransferase activity	molecular_function	Catalysis of the reaction: bixin + S-adenosyl-L-methionine <=> bixin dimethyl ester + S-adenosyl-L-homocysteine.
GO:0102822	quercetin 3'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine = H+ + isorhamnetin + S-adenosyl-L-homocysteine.
GO:0102823	kaempferol-3-rhamnoside-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP.
GO:0102824	UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP.
GO:0102825	quercetin 3-O-rhamnoside-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP.
GO:0102826	kaempferol-3-glucoside-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP.
GO:0102827	galactosylononitol-raffinose galactosyltransferase activity	molecular_function	Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol.
GO:0102828	stachyose galactinol:verbascose galactosyltransferase activity	molecular_function	Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol.
GO:0102829	ajugose synthase activity	molecular_function	Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose.
GO:0102830	verbascose synthase activity	molecular_function	Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose.
GO:0102831	stachyose synthase activity	molecular_function	Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose.
GO:0102832	verbascose galactinol:ajugose galactosyltransferase activity	molecular_function	Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol.
GO:0102833	sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity	molecular_function	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol.
GO:0102834	1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102835	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102836	1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102837	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102838	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102839	1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102840	1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102841	1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102842	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming)	molecular_function	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102843	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)	molecular_function	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102844	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)	molecular_function	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102845	1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102846	1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102847	1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102848	1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102849	1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102850	1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity	molecular_function	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102851	1-18:2-2-16:0-phosphatidylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102852	1-18:3-2-16:0-phosphatidylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102853	1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102854	1-18:2-2-18:1-phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102856	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102858	1-18:2-2-18:3-phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102859	1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)	molecular_function	Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102862	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming)	molecular_function	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102863	1-18:3-2-18:1-phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102864	1-18:3-2-18:2-phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102865	delta6-acyl-lipid desaturase activity	molecular_function	Catalysis of the reaction: a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ <=> a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.
GO:0102866	di-homo-gamma-linolenate delta5 desaturase activity	molecular_function	Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor.
GO:0102867	molybdenum cofactor sulfurtransferase activity	molecular_function	Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine <=> thio-molybdenum cofactor + L-alanine + H2O.
GO:0102868	24-epi-campsterol desaturase activity	molecular_function	Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O.
GO:0102869	6-hydroxyflavone-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+.
GO:0102870	7-hydroxyflavone-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+.
GO:0102872	1-16:0-2-18:2-phosphatidylcholine desaturase activity	molecular_function	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.
GO:0102873	1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102874	1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102875	1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity	molecular_function	Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
GO:0102876	psoralen synthase activity	molecular_function	Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O.
GO:0102877	alpha-copaene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid.
GO:0102878	(+)-alpha-barbatene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid.
GO:0102879	(+)-thujopsene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid.
GO:0102880	isobazzanene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid.
GO:0102881	(+)-beta-barbatene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid.
GO:0102882	beta-acoradiene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid.
GO:0102883	(+)-beta-chamigrene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid.
GO:0102884	alpha-zingiberene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid.
GO:0102885	alpha-cuprenene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid.
GO:0102886	alpha-chamigrene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid.
GO:0102887	beta-sesquiphellandrene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid.
GO:0102888	delta-cuprenene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid.
GO:0102889	beta-elemene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid.
GO:0102890	naringenin chalcone 4'-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+.
GO:0102891	2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP.
GO:0102892	betanidin 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP.
GO:0102893	betanidin 6-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP.
GO:0102894	UDPG:cyclo-DOPA 5-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP.
GO:0102895	colneleate synthase activity	molecular_function	Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O.
GO:0102896	colnelenate synthase activity	molecular_function	Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O.
GO:0102897	abietadienal hydroxylase activity	molecular_function	Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O.
GO:0102898	levopimaradienol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O.
GO:0102899	dehydroabietadienol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O.
GO:0102900	dehydroabietadienal hydroxylase activity	molecular_function	Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O.
GO:0102901	isopimaradienol hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O.
GO:0102902	isopimaradienal hydroxylase activity	molecular_function	Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O.
GO:0102903	gamma-terpinene synthase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid.
GO:0102904	germacrene C synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid.
GO:0102905	valencene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid.
GO:0102906	7-epi-alpha-selinene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid.
GO:0102907	sesquisabinene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene.
GO:0102910	dirigent protein activity	molecular_function	Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O.
GO:0102911	(-)-secoisolariciresinol dehydrogenase activity	molecular_function	Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH.
GO:0102912	(-)-lactol dehydrogenase activity	molecular_function	Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH.
GO:0102913	3-aminomethylindole N-methyltransferase activity	molecular_function	Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine.
GO:0102914	N-methyl-3-aminomethylindole N-methyltransferase activity	molecular_function	Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine.
GO:0102915	piperitol synthase activity	molecular_function	Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O.
GO:0102916	sesamin synthase activity	molecular_function	Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O.
GO:0102917	(S)-reticuline 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine.
GO:0102918	(R)-reticuline 7-O-methyltransferase activity	molecular_function	Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine + H+.
GO:0102919	5,6-dimethylbenzimidazole synthase activity	molecular_function	Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid.
GO:0102920	acyl coenzyme A: isopenicillin N acyltransferase activity	molecular_function	Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate.
GO:0102921	mannosylglycerate synthase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP.
GO:0102922	phenylpropanoyltransferase activity	molecular_function	Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A.
GO:0102923	3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity	molecular_function	Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A.
GO:0102924	gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide.
GO:0102925	solanine UDP-galactose galactosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP.
GO:0102926	solanidine glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP.
GO:0102927	beta-chaconine rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP.
GO:0102928	beta-solanine rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP.
GO:0102929	lachrymatory factor synthase activity	molecular_function	Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide.
GO:0102930	4-hydroxybenzoate geranyltransferase activity	molecular_function	Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid.
GO:0102931	(Z,E)-alpha- farnesene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid.
GO:0102932	pterocarpan reductase activity	molecular_function	Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP.
GO:0102933	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity	molecular_function	Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate.
GO:0102934	costunolide synthase activity	molecular_function	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.
GO:0102935	gypsogenin-UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.
GO:0102936	gypsogenate-UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP.
GO:0102937	16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP.
GO:0102938	orcinol O-methyltransferase activity	molecular_function	Catalysis of the reaction: orcinol + S-adenosyl-L-methionine = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine.
GO:0102939	3-methoxy-5-hydroxytoluene O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine.
GO:0102940	phloroglucinol O-methyltransferase activity	molecular_function	Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine.
GO:0102941	3,5-dihydroxyanisole O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine.
GO:0102942	3,5-dimethoxyphenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine.
GO:0102943	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity	molecular_function	Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate.
GO:0102944	medicagenate UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside.
GO:0102945	soyasapogenol B UDP-glucosyl transferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside.
GO:0102946	soyasapogenol E UDP-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside.
GO:0102947	(+)-delta-cadinene-8-hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O.
GO:0102948	luteolin C-glucosyltransferase activity	molecular_function	Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor.
GO:0102949	1,2-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.
GO:0102950	indole-3-acetyl-valine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid.
GO:0102951	indole-3-acetyl-phenylalanine synthetase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid.
GO:0102952	UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP.
GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity	molecular_function	Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B.
GO:0102954	dalcochinase activity	molecular_function	Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose.
GO:0102955	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity	molecular_function	Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+.
GO:0102956	UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP.
GO:0102960	momilactone-A synthase activity	molecular_function	Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H.
GO:0102963	(S)-corytuberine synthase activity	molecular_function	Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O.
GO:0102964	S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity	molecular_function	Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine <=> H+ + magnoflorine + S-adenosyl-L-homocysteine.
GO:0102965	alcohol-forming long-chain fatty acyl-CoA reductase activity	molecular_function	Catalysis of the reaction: a long-chain fatty acyl-CoA + 2 H+ + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP+. A long-chain fatty acid (LCFA) is a fatty acid with an aliphatic tail of 13 to 21 carbons.
GO:0102966	arachidoyl-CoA:1-dodecanol O-acyltransferase activity	molecular_function	Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A.
GO:0102967	10-hydroxygeraniol oxidoreductase activity	molecular_function	Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+.
GO:0102968	10-hydroxygeranial oxidoreductase activity	molecular_function	Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+.
GO:0102969	10-oxogeraniol oxidoreductase activity	molecular_function	Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+.
GO:0102970	7-deoxyloganetic acid glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP.
GO:0102971	phosphinothricin N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate.
GO:0102972	gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)	molecular_function	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide.
GO:0102973	norsolorinate anthrone synthase activity	molecular_function	Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein].
GO:0102974	hydroxyversicolorone reductase activity	molecular_function	Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH.
GO:0102975	versiconal hemiacetal acetate reductase activity	molecular_function	Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH.
GO:0102976	versiconal reductase activity	molecular_function	Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+.
GO:0102977	nitrilotriacetate monooxygenase activity (FMN-dependent)	molecular_function	Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN.
GO:0102978	furaneol oxidoreductase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+.
GO:0102979	homofuraneol oxidoreductase activity	molecular_function	Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.
GO:0102980	2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity	molecular_function	Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.
GO:0102981	4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+.
GO:0102982	UDP-3-dehydro-alpha-D-glucose dehydrogenase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH.
GO:0102983	xylogalacturonan beta-1,3-xylosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan.
GO:0102984	sulfoacetaldehyde dehydrogenase activity	molecular_function	Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+.
GO:0102985	delta12-fatty-acid desaturase activity	molecular_function	Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9.
GO:0102986	trehalose synthase activity	molecular_function	Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate.
GO:0102987	palmitoleic acid delta 12 desaturase activity	molecular_function	Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor.
GO:0102988	9,12-cis-hexadecadienoic acid delta 15 desaturase activity	molecular_function	Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.
GO:0102989	5-pentadecatrienylresorcinol synthase activity	molecular_function	Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide.
GO:0102990	5-n-alk(en)ylresorcinol O-methyltransferase activity	molecular_function	Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine.
GO:0102991	myristoyl-CoA hydrolase activity	molecular_function	Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A.
GO:0102992	2-methylbutyronitrile hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile.
GO:0102993	linolenate delta15 desaturase activity	molecular_function	Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor.
GO:0102995	angelicin synthase activity	molecular_function	Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O.
GO:0102996	beta,beta digalactosyldiacylglycerol galactosyltransferase activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol.
GO:0102997	progesterone 5beta- reductase activity	molecular_function	Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP.
GO:0102998	4-sulfomuconolactone hydrolase activity	molecular_function	Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+.
GO:0102999	UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+.
GO:0103000	UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+.
GO:0103001	dimethylsulfoxide oxygenase activity	molecular_function	Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP.
GO:0103002	16-hydroxypalmitate dehydrogenase activity	molecular_function	Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH.
GO:0103003	oleate peroxygenase activity	molecular_function	Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol.
GO:0103004	9,10-epoxystearate hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP.
GO:0103005	9,10-epoxystearate hydrolase activity	molecular_function	Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate.
GO:0103006	9,10-dihydroxystearate hydroxylase activity	molecular_function	Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP.
GO:0103007	indole-3-acetate carboxyl methyltransferase activity	molecular_function	Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine.
GO:0103008	4-chloro-2-methylphenoxyacetate oxygenase activity	molecular_function	Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide.
GO:0103009	3-chlorotoluene monooxygenase activity	molecular_function	Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O.
GO:0103010	gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)	molecular_function	Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide.
GO:0103011	mannosylfructose-phosphate synthase activity	molecular_function	Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP.
GO:0103012	ferredoxin-thioredoxin reductase activity	molecular_function	Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.
GO:0103015	4-amino-4-deoxy-L-arabinose transferase activity	molecular_function	Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.
GO:0103016	tRNA-specific 2-thiouridylase activity	molecular_function	Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine.
GO:0103020	1-deoxy-D-xylulose kinase activity	molecular_function	Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP.
GO:0103023	ITPase activity	molecular_function	Catalysis of the reaction: ITP + H2O = IDP + H+ + phosphate.
GO:0103026	fructose-1-phosphatase activity	molecular_function	Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate.
GO:0103027	FMN phosphatase activity	molecular_function	Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate.
GO:0103028	murein hydrolase activity	molecular_function	Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide.
GO:0103031	L-Ala-D/L-Glu epimerase activity	molecular_function	Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate.
GO:0103033	beta-galactosidase activity (lactose isomerization)	molecular_function	Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose.
GO:0103035	NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity	molecular_function	Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP.
GO:0103036	NADH:menaquinone oxidoreductase activity	molecular_function	Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol.
GO:0103037	L-glyceraldehyde 3-phosphate reductase activity	molecular_function	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH.
GO:0103039	protein methylthiotransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.
GO:0103040	aldose sugar dehydrogenase activity	molecular_function	Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor.
GO:0103041	thiosulfate-thioredoxin sulfurtransferase activity	molecular_function	Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.
GO:0103042	4-hydroxy-L-threonine aldolase activity	molecular_function	Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine.
GO:0103043	5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity	molecular_function	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate.
GO:0103044	ribosomal protein S6 glutamate-glutamate ligase activity	molecular_function	Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate.
GO:0103045	methione N-acyltransferase activity	molecular_function	Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+.
GO:0103046	alanylglutamate dipeptidase activity	molecular_function	Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate.
GO:0103047	methyl beta-D-glucoside 6-phosphate glucohydrolase activity	molecular_function	Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.
GO:0103048	tRNA m2A37 methyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA.
GO:0103054	gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)	molecular_function	Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate.
GO:0103055	gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O.
GO:0103056	gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate.
GO:0103057	gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity	molecular_function	Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate.
GO:0103058	kaempferol 3-glucoside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP.
GO:0103059	UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-).
GO:0103060	kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.
GO:0103061	trans-methoxy-C60-meroacyl-AMP ligase activity	molecular_function	Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein].
GO:0103062	cis-keto-C60-meroacyl-AMP ligase activity	molecular_function	Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].
GO:0103063	trans-keto-C61-meroacyl-AMP ligase activity	molecular_function	Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].
GO:0103064	inositol phosphorylceramide mannosyltransferase activity	molecular_function	Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+.
GO:0103066	4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity	molecular_function	Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.
GO:0103067	4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity	molecular_function	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.
GO:0103068	leukotriene C4 gamma-glutamyl transferase activity	molecular_function	Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid.
GO:0103069	17-hydroxyprogesterone 21-hydroxylase activity	molecular_function	Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0103072	straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity	molecular_function	Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde.
GO:0103074	glucose-6-phosphate 3-dehydrogenase activity	molecular_function	Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.
GO:0103075	indole-3-pyruvate monooxygenase activity	molecular_function	Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O.
GO:0103077	quercetin 3-glucoside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP.
GO:0103078	quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP.
GO:0103079	2-(3'-methylthio)propylmalate synthase activity	molecular_function	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A.
GO:0103080	methylthiopropylmalate isomerase activity	molecular_function	Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate.
GO:0103082	2-(4'-methylthio)butylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A.
GO:0103083	methylthiobutylmalate isomerase activity	molecular_function	Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate.
GO:0103085	2-(5'-methylthio)pentylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A.
GO:0103086	methylthiopentylmalate isomerase activity	molecular_function	Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate.
GO:0103088	2-(6'-methylthio)hexylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A.
GO:0103089	methylthiohexylmalate isomerase activity	molecular_function	Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate.
GO:0103091	2-(7'-methylthio)heptylmalate synthase activity	molecular_function	Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A.
GO:0103092	methylthioalkylmalate isomerase activity	molecular_function	Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate.
GO:0103096	CYP79F1 dihomomethionine monooxygenase activity	molecular_function	Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP.
GO:0103097	CYP79F1 trihomomethionine monooxygenase activity	molecular_function	Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime.
GO:0103098	CYP79F1 tetrahomomethionine monooxygenase activity	molecular_function	Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime.
GO:0103099	UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP.
GO:0103100	UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-).
GO:0103101	UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP.
GO:0103102	UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.
GO:0103103	UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+.
GO:0103104	6-methylthiohexyldesulfoglucosinolate sulfotransferase activity	molecular_function	Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate.
GO:0103105	2-oxo-6-methylthiohexanoate aminotransferase activity	molecular_function	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate.
GO:0103106	brassinolide 23-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+.
GO:0103107	castasterone 23-O-glucosyltransferase activity	molecular_function	Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+.
GO:0103111	D-glucosamine PTS permease activity	molecular_function	Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine.
GO:0103116	ABC-type D-galactofuranose transporter	molecular_function	Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.
GO:0103117	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity	molecular_function	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate.
GO:0103118	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity	molecular_function	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein].
GO:0104004	cellular response to environmental stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.
GO:0106001	intestinal hexose absorption	biological_process	Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.
GO:0106002	mCRD-mediated mRNA stability complex	cellular_component	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.
GO:0106003	amyloid-beta complex	cellular_component	Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease.
GO:0106004	tRNA (guanine-N7)-methylation	biological_process	The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.
GO:0106005	RNA 5'-cap (guanine-N7)-methylation	biological_process	The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.
GO:0106006	cytoskeletal protein-membrane anchor activity	molecular_function	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location.
GO:0106007	microtubule anchoring at cell cortex of cell tip	biological_process	Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex.
GO:0106008	2-oxoglutaramate amidase activity	molecular_function	Catalysis of the reaction: 2-oxoglutaramate + H2O = 2-oxoglutarate + NH3.
GO:0106009	(4S)-4-hydroxy-2-oxoglutarate aldolase activity	molecular_function	Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
GO:0106011	regulation of protein localization to medial cortex	biological_process	Any process that regulates the localization of a protein to the medial cortex.
GO:0106012	positive regulation of protein localization to medial cortex	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex.
GO:0106013	negative regulation of protein localization to cell cortex of cell tip	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip.
GO:0106014	regulation of inflammatory response to wounding	biological_process	Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.
GO:0106015	negative regulation of inflammatory response to wounding	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
GO:0106016	positive regulation of inflammatory response to wounding	biological_process	Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
GO:0106017	phosphatidylinositol-3,4-bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	molecular_function	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
GO:0106020	regulation of vesicle docking	biological_process	Any process that modulates the frequency, rate or extent of vesicle docking.
GO:0106021	negative regulation of vesicle docking	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking.
GO:0106022	positive regulation of vesicle docking	biological_process	Any process that activates or increases the frequency, rate or extent of vesicle docking.
GO:0106023	regulation of pupariation	biological_process	Any process that modulates the onset of pupariation.
GO:0106024	negative regulation of pupariation	biological_process	Any process that stops, prevents or reduces the rate of onset of pupariation.
GO:0106025	positive regulation of pupariation	biological_process	Any process that activates or increases the frequency, rate or extent of onset of pupariation.
GO:0106026	Gly-tRNA(Ala) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala).
GO:0106027	neuron projection organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.
GO:0106028	neuron projection retraction	biological_process	The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:0106029	tRNA pseudouridine synthase activity	molecular_function	Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
GO:0106030	neuron projection fasciculation	biological_process	The collection of neuronal projections into a bundle of rods, known as a fascicle.
GO:0106032	snRNA pseudouridine synthase activity	molecular_function	Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
GO:0106033	spine synapse	cellular_component	A type of synapse occurring between an axon and a dendritic spine.
GO:0106034	protein maturation by [2Fe-2S] cluster transfer	biological_process	The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
GO:0106035	protein maturation by [4Fe-4S] cluster transfer	biological_process	The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
GO:0106036	assembly of apicomedial cortex actomyosin	biological_process	A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.
GO:0106037	apicomedial cortex	cellular_component	The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell.
GO:0106040	regulation of GABA-A receptor activity	biological_process	Any process that modulates the frequency, rate or extent of GABA-A receptor activity.
GO:0106041	positive regulation of GABA-A receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.
GO:0106042	negative regulation of GABA-A receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.
GO:0106044	guanine deglycation	biological_process	The removal of a sugar or dicarbonyl from a glycated guanine.
GO:0106045	guanine deglycation, methylglyoxal removal	biological_process	The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.
GO:0106046	guanine deglycation, glyoxal removal	biological_process	The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine.
GO:0106047	polyamine deacetylation	biological_process	The modification of acetylpolyamine by the removal of acetyl groups.
GO:0106048	spermidine deacetylation	biological_process	The modification of acetylspermadine by the removal of acetyl groups.
GO:0106049	regulation of cellular response to osmotic stress	biological_process	Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.
GO:0106050	tRNA 2'-O-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.
GO:0106054	tRNA U34 sulfurtransferase activity	molecular_function	Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.
GO:0106055	mannosyl-oligosaccharide 1,2-alpha-mannosidase complex	cellular_component	A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
GO:0106056	regulation of calcineurin-mediated signaling	biological_process	Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.
GO:0106057	negative regulation of calcineurin-mediated signaling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling.
GO:0106058	positive regulation of calcineurin-mediated signaling	biological_process	Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.
GO:0106059	tRNA (cytidine 56-2'-O)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.
GO:0106060	regulation of exit from meiosis	biological_process	Any process that modulates the frequency, rate or extent of exit from mitosis.
GO:0106061	negative regulation of exit from meiosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.
GO:0106062	positive regulation of exit from meiosis	biological_process	Any process that activates or increases the frequency, rate or extent of exit from meiosis.
GO:0106063	G protein-coupled folate receptor activity	molecular_function	Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.
GO:0106064	regulation of cobalamin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
GO:0106068	SUMO ligase complex	cellular_component	A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.
GO:0106069	synapsis initiation complex	cellular_component	A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
GO:0106071	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	molecular_function	Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity	biological_process	Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.
GO:0106075	peptide N-succinyltransferase activity	molecular_function	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.
GO:0106076	peptide-lysine-N-succinyltransferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.
GO:0106077	histone succinylation	biological_process	The modification of a histone by the addition of an succinyl group.
GO:0106078	histone succinyltransferase activity	molecular_function	Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.
GO:0106080	GATOR1 complex binding	molecular_function	Binding to a GATOR1 complex.
GO:0106081	maltose import across plasma membrane	biological_process	The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol.
GO:0106082	sucrose import across plasma membrane	biological_process	The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol.
GO:0106083	nuclear membrane protein complex	cellular_component	Any protein complex that is part of the nuclear membrane.
GO:0106084	mitotic nuclear membrane microtubule tethering complex	cellular_component	A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane.
GO:0106088	regulation of cell adhesion involved in sprouting angiogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
GO:0106089	negative regulation of cell adhesion involved in sprouting angiogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
GO:0106090	positive regulation of cell adhesion involved in sprouting angiogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
GO:0106091	glial cell projection elongation	biological_process	The process of creating an elongation or projection from a glial cell.
GO:0106092	glial cell projection elongation involved in axon ensheathment	biological_process	The extension of a glial cell process or projection to wrap around an axon.
GO:0106093	EDS1 disease-resistance complex	cellular_component	A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes.
GO:0106094	nuclear membrane microtubule tethering complex	cellular_component	A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.
GO:0106095	m7G(5')pppN diphosphatase complex	cellular_component	A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide.
GO:0106096	response to ceramide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.
GO:0106097	cellular response to ceramide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.
GO:0106098	NAGS/NAGK complex	cellular_component	A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.
GO:0106099	2-keto-3-deoxy-L-rhamnonate aldolase activity	molecular_function	Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.
GO:0106100	beta-pinacene synthase activity	molecular_function	Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene.
GO:0106101	ER-dependent peroxisome localization	biological_process	A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.
GO:0106103	COPII vesicles tethering complex	cellular_component	A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae.
GO:0106104	regulation of glutamate receptor clustering	biological_process	Any process that modulates the frequency, rate or extent of glutamate receptor clustering.
GO:0106105	Ala-tRNA(Thr) hydrolase activity	molecular_function	Catalysis of the hydrolysis of misacylated ala-tRNA(thr).
GO:0106106	cold-induced thermogenesis	biological_process	The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.
GO:0106107	regulation of (R)-mevalonic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
GO:0106108	negative regulation of (R)-mevalonic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
GO:0106109	positive regulation of (R)-mevalonic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
GO:0106110	vomitoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.
GO:0106111	regulation of mitotic cohesin ssDNA (lagging strand) loading	biological_process	Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
GO:0106112	negative regulation of mitotic cohesin ssDNA (lagging strand) loading	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
GO:0106113	positive regulation of mitotic cohesin ssDNA (lagging strand) loading	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
GO:0106114	regulation of mitotic cohesin dsDNA (leading strand) loading	biological_process	Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
GO:0106115	negative regulation of mitotic cohesin dsDNA (leading strand) loading	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
GO:0106116	positive regulation of mitotic cohesin dsDNA (leading strand) loading	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
GO:0106117	acidocalcisome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
GO:0106118	regulation of sterol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.
GO:0106119	negative regulation of sterol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.
GO:0106120	positive regulation of sterol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.
GO:0106121	positive regulation of cobalamin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.
GO:0106122	negative regulation of cobalamin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.
GO:0106123	reservosome	cellular_component	A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.
GO:0106124	reservosome lumen	cellular_component	The volume enclosed by the membranes of a reservosome.
GO:0106125	reservosome matrix	cellular_component	A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.
GO:0106126	reservosome membrane	cellular_component	The lipid bilayer surrounding a reservosome.
GO:0106128	negative regulation of store-operated calcium entry	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.
GO:0106129	positive regulation of store-operated calcium entry	biological_process	Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.
GO:0106130	purine phosphoribosyltransferase activity	molecular_function	Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.
GO:0106134	positive regulation of cardiac muscle cell contraction	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.
GO:0106135	negative regulation of cardiac muscle cell contraction	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.
GO:0106136	lectin-induced modified bacterial internalization	biological_process	The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0106137	IkappaB kinase complex binding	molecular_function	Binding to a IkappaB kinase complex.
GO:0106138	Sec61 translocon complex binding	molecular_function	Binding to a Sec61 translocon complex.
GO:0106139	symbiont cell surface	cellular_component	The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
GO:0106140	P-TEFb complex binding	molecular_function	Binding to a P-TEFb complex.
GO:0106141	flavin prenyltransferase activity	molecular_function	Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate.
GO:0106142	rRNA (adenine-N1-)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.
GO:0106143	tRNA (m7G46) methyltransferase complex	cellular_component	A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).
GO:0106144	fraxetin 5-hydroxylase activity	molecular_function	Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20.
GO:0106145	scopoletin 8-hydroxylase activity	molecular_function	Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2).
GO:0106146	sideretin biosynthesis	biological_process	The chemical reactions and pathways resulting in the formation of sideretin.
GO:0106147	fraxetin biosynthesis	biological_process	The chemical reactions and pathways resulting in the formation of fraxetin.
GO:0106148	4-hydroxyindole-3- carbonyl nitrile biosynthesis	biological_process	The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.
GO:0106149	indole-3-carbonyl nitrile 4-hydroxylase activity	molecular_function	Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP+ + H20.
GO:0106150	zearalenone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.
GO:0106151	CNBH domain intrinsic ligand binding	molecular_function	Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide.
GO:0106153	phosphorylated histone binding	molecular_function	Binding to a histone in which a residue has been modified by phosphorylation.
GO:0106154	perithecium formation	biological_process	The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.
GO:0106155	peptidyl-lysine 3-dioxygenase activity	molecular_function	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.
GO:0106156	peptidyl-lysine 4-dioxygenase activity	molecular_function	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.
GO:0106157	peptidyl-arginine 3-dioxygenase activity	molecular_function	Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.
GO:0106158	glycero-3-phosphocholine acyltransferase activity	molecular_function	Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine.
GO:0106162	mRNA N-acetyltransferase activity	molecular_function	Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H+ + phosphate.
GO:0106163	regulation of exonucleolytic catabolism of deadenylated mRNA	biological_process	Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
GO:0106164	positive regulation of exonucleolytic catabolism of deadenylated mRNA	biological_process	Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
GO:0106165	negative regulation of exonucleolytic catabolism of deadenylated mRNA	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
GO:0106166	spindle pole body-nuclear membrane anchor activity	molecular_function	The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body.
GO:0106167	extracellular ATP signaling	biological_process	The series of molecular signals mediated by the detection of extracellular ATP.
GO:0106172	COPI-coated vesicle lumen	cellular_component	The volume enclosed by the membrane of a COPI-coated endocytic vesicle.
GO:0106173	COPII-coated vesicle lumen	cellular_component	The volume enclosed by the membrane of a COPII-coated endocytic vesicle.
GO:0106174	phagolysosome vesicle lumen	cellular_component	The volume enclosed by the membrane of a phagolysosome.
GO:0106175	phagolysosome vesicle membrane	cellular_component	The lipid bylayer surrounding a phagolysosome.
GO:0106176	clathrin-coated endocytic vesicle lumen	cellular_component	The volume enclosed by the membrane of a clathrin-coated endocytic vesicle.
GO:0106177	cyclic-GMP-AMP hydrolase activity	molecular_function	Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP.
GO:0106186	cytoplasmic side of plasma membrane, cell tip	cellular_component	The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
GO:0106210	culmorin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris.
GO:0106211	inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity	molecular_function	Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H+ + phosphate.
GO:0106212	centromere detachment from spindle pole body involved in meiotic chromosome organization	biological_process	The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.
GO:0106213	kinetochore disassembly involved in meiotic chromosome organization	biological_process	The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.
GO:0106214	regulation of vesicle fusion with Golgi apparatus	biological_process	Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.
GO:0106215	negative regulation of vesicle fusion with Golgi apparatus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.
GO:0106216	positive regulation of vesicle fusion with Golgi apparatus	biological_process	Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.
GO:0106217	tRNA C3-cytosine methylation	biological_process	The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine.
GO:0106218	galactosaminogalactan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).
GO:0106219	zinc ion sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of zinc.
GO:0106220	pyocyanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group.
GO:0106222	lncRNA binding	molecular_function	Binding to a long noncoding RNA (lncRNA).
GO:0106223	germacrene A hydroxylase activity	molecular_function	Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].
GO:0106225	peptidyl-lysine 2-hydroxyisobutyrylation	biological_process	The 2-hydroxyisobutyrylation of a lysine residue in a protein.
GO:0106226	peptide 2-hydroxyisobutyryltransferase activity	molecular_function	Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide.
GO:0106227	peptidyl-lysine glutarylation	biological_process	The glutarylation of a lysine residue in a protein.
GO:0106228	peptide glutaryltransferase activity	molecular_function	Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein].
GO:0106229	histone glutaryltransferase activity	molecular_function	Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone.
GO:0106230	protein depropionylation	biological_process	The removal of a propionyl group from a residue in a peptide or protein.
GO:0106231	protein-propionyllysine depropionylase activity	molecular_function	Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD+ = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0106232	hydroxyisourate hydrolase complex	cellular_component	A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin.
GO:0106233	glycosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
GO:0106234	outer membrane protein complex	cellular_component	Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC.
GO:0106235	ceramide-1-phosphate phosphatase activity	molecular_function	Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate.
GO:0106236	rhamnolipid biosynthesis	biological_process	The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.
GO:0106237	arachidonate 12(R)-lipoxygenase activity	molecular_function	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
GO:0106238	peregrinol diphosphate synthase activity	molecular_function	Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O.
GO:0106239	9,13-epoxylabda-14-ene synthase activity	molecular_function	Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate.
GO:0106240	labd-13Z-ene-9,15,16-triol synthase activity	molecular_function	Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H+ + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase].
GO:0106242	kolavenyl diphosphate synthase activity	molecular_function	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate.
GO:0106243	syn-isopimara-7,15-diene synthase activity	molecular_function	Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene.
GO:0106244	eupatolide synthase activity	molecular_function	Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase].
GO:0106245	L-serine-phosphatidylethanolamine phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine.
GO:0106246	regulation of poly(A)-specific ribonuclease activity	biological_process	Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
GO:0106247	negative regulation of poly(A)-specific ribonuclease activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.
GO:0106248	positive regulation of poly(A)-specific ribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity.
GO:0106249	Nicalin-NOMO complex	cellular_component	A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147.
GO:0106250	DNA-binding transcription repressor activity, RNA polymerase III-specific	molecular_function	A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.
GO:0106251	N4-acetylcytidine amidohydrolase activity	molecular_function	Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate.
GO:0106253	positive regulation of DNA strand resection involved in replication fork processing	biological_process	Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing.
GO:0106254	lipid sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid.
GO:0106255	hydroperoxy icosatetraenoate isomerase activity	molecular_function	A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate.
GO:0106256	hydroperoxy icosatetraenoate dehydratase activity	molecular_function	A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H2O.
GO:0106258	L-serine-phosphatidylcholine phosphatidyltransferase activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline.
GO:0106259	cell-to-cell migration in host	biological_process	The directional movement of a symbiont from one host cell to another.
GO:0106260	DNA-DNA tethering activity	molecular_function	Bridging together two regions of a DNA molecule.
GO:0106261	tRNA uridine(34) acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H+ + L-methionine.
GO:0106262	1-acylglycerophosphoethanolamine O-acyltransferase activity	molecular_function	Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.
GO:0106263	1-acylglycerophosphoserine O-acyltransferase activity	molecular_function	Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.
GO:0106264	protein serine kinase activity (using GTP as donor)	molecular_function	Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein].
GO:0106265	THPH synthase activity	molecular_function	Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA.
GO:0106266	3-chloro THPH synthase activity	molecular_function	Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O.
GO:0106267	3,5 dichloro-THPH synthase activity	molecular_function	Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O.
GO:0106268	3,5-dichloro-THPH methyl transferase activity	molecular_function	Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.
GO:0106271	D-arabinose 1-dehydrogenase (NADP+) activity	molecular_function	Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH.
GO:0106272	protein localization to ERGIC	biological_process	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).
GO:0106273	cytosol to ERGIC protein transport	biological_process	The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).
GO:0106274	NAD+-protein-arginine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-arginyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide.
GO:0106276	biliberdin reductase NAD+ activity	molecular_function	Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+.
GO:0106277	biliverdin reductase (NADP+) activity	molecular_function	Catalysis of the reaction: bilirubin + NADP+ = biliverdin + NADPH + H+.
GO:0106278	regulation of UDP-N-acetylglucosamine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process.
GO:0106279	negative regulation of UDP-N-acetylglucosamine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.
GO:0106280	positive regulation of UDP-N-acetylglucosamine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.
GO:0106281	chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: chenodeoxycholate + NAD+ = 7-oxolithocholate + H+ + NADH.
GO:0106282	isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD+ = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H+ + NADH.
GO:0106283	ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	molecular_function	Catalysis of the reaction: NAD+ + ursodeoxycholate = 7-oxolithocholate + H+ + NADH.
GO:0106286	(E)-caffeate-CoA ligase activity	molecular_function	Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate.
GO:0106288	regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	biological_process	Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.
GO:0106289	negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.
GO:0106290	trans-cinnamate-CoA ligase activity	molecular_function	Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.
GO:0106291	superoxide-generating NADH oxidase activity	molecular_function	Catalysis of the reaction: NADH + 2 O2 = H+ + NAD+ + 2 superoxide.
GO:0106292	superoxide-generating NADPH oxidase activity	molecular_function	Catalysis of the reaction: NADPH + 2 O2 = H+ + NADP+ + 2 superoxide.
GO:0106293	NADH oxidase H202-forming activity	molecular_function	Catalysis of the reaction: NADH + H+ + O2 = NAD + hydrogen peroxide (H2O2).
GO:0106294	NADPH oxidase H202-forming activity	molecular_function	Catalysis of the reaction: NADPH + H+ + O2 = NADP + hydrogen peroxide (H2O2).
GO:0106295	resolvin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.
GO:0106296	D-series resolvin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.
GO:0106297	E-series resolvin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.
GO:0106298	13-series resolvin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid.
GO:0106299	resolution phase response	biological_process	An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.
GO:0106300	protein-DNA covalent cross-linking repair	biological_process	The removal of covalent cross-link between DNA and a protein.
GO:0106301	arachidonic acid 5,6-epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid.
GO:0106302	arachidonic acid 8,9-epoxygenase activity	molecular_function	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid.
GO:0106303	mannogen metabolic process	biological_process	The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.
GO:0106304	mannogen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.
GO:0106305	mannogen catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.
GO:0106309	progesterone 21-hydroxylase activity	molecular_function	Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0106310	protein serine kinase activity	molecular_function	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
GO:0106312	methylenetetrahydrofolate reductase NADH activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD + = 5,10-methylenetetrahydrofolate + NADH + H+.
GO:0106313	methylenetetrahydrofolate reductase NADPH activity	molecular_function	Catalysis of the reaction: 5-methyltetrahydrofolate + NADP + = 5,10-methylenetetrahydrofolate + NADPH + H+.
GO:0106314	nitrite reductase NADPH activity	molecular_function	Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+.
GO:0106316	nitrite reductase NADH activity	molecular_function	Catalysis of the reaction: ammonium hydroxide + 3 NAD+ + H2O = nitrite + 3 NADH + 3 H+.
GO:0106317	methane monooxygenase NADH activity	molecular_function	Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O.
GO:0106318	methane monooxygenase NADPH activity	molecular_function	Catalysis of the reaction: methane + NADPH + H+ + O2 = methanol + NADP+ + H2O.
GO:0106319	(R)-limonene 1,2-monooxygenase NADH activity	molecular_function	Catalysis of the reaction: (4R)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4R)-limonene-1,2-epoxide.
GO:0106320	(R)-limonene 1,2-monooxygenase NADPH activity	molecular_function	Catalysis of the reaction: (4R)-limonene + NADPH + H+ + O2 = NADP+ + H2O + (4R)-limonene-1,2-epoxide.
GO:0106321	S-(hydroxymethyl)glutathione dehydrogenase NADP activity	molecular_function	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.
GO:0106322	S-(hydroxymethyl)glutathione dehydrogenase NAD activity	molecular_function	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+.
GO:0106323	(S)-limonene 1,2-monooxygenase NADPH activity	molecular_function	Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide.
GO:0106324	(S)-limonene 1,2-monooxygenase NADH activity	molecular_function	Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide.
GO:0106325	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP.
GO:0106326	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H+ + UDP.
GO:0106327	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H+ + UDP.
GO:0106328	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H+ + UDP.
GO:0106329	L-phenylalaine oxidase activity	molecular_function	Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+).
GO:0106330	sialate 9-O-acetylesterase activity	molecular_function	Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.
GO:0106331	sialate 4-O-acetylesterase activity	molecular_function	Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H+ + N-acetylneuraminate.
GO:0106332	ds/ssDNA junction-specific dsDNA endonuclease activity	molecular_function	Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction.
GO:0106333	subcortical maternal complex	cellular_component	Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex.
GO:0106334	3'-deoxyribose phosphate lyase activity	molecular_function	Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate.
GO:0106335	tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	molecular_function	Catalysis of the reaction: carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine.
GO:0106336	yolk syncytial layer development	biological_process	The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm.
GO:0106339	tRNA (cytidine 32-2'-O)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA.
GO:0106340	tRNA (guanosine 34-2'-O)-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 34 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 34 in tRNA.
GO:0106341	omega-hydroxyceramide transacylase activity	molecular_function	Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.
GO:0106342	omega-hydroxyceramide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.
GO:0106343	glutarate dioxygenase activity	molecular_function	Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2.
GO:0106344	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP	molecular_function	Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].
GO:0106345	glyoxylate reductase activity	molecular_function	Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.
GO:0106346	snRNA methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.
GO:0106347	U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity	molecular_function	Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.
GO:0106348	U2 snRNA adenosine m6 methytransferase activity	molecular_function	Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.
GO:0106349	snRNA methylation	biological_process	The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.
GO:0106350	octaprenyl pyrophosphate synthase activity	molecular_function	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate.
GO:0106354	tRNA surveillance	biological_process	The set of processes involved in identifying and degrading defective or aberrant tRNAs.
GO:0106355	4-hydroxybenzoate 3-monooxygenase [NADH] activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+.
GO:0106356	4-hydroxybenzoate 3-monooxygenase [NADPH] activity	molecular_function	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.
GO:0106357	glycerol-1-phosphate dehydrogenase [NAD+] activity	molecular_function	Catalysis of the reaction: NAD+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADH.
GO:0106358	glycerol-1-phosphate dehydrogenase [NADP+] activity	molecular_function	Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH.
GO:0106359	2-hydroxyacyl-CoA lyase activity	molecular_function	Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.
GO:0106361	protein-arginine rhamnosyltransferase activity	molecular_function	Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H+ + N(omega)-(L-rhamnosyl)-L-arginyl-[protein].
GO:0106362	protein-arginine N-acetylglucosaminyltransferase activity	molecular_function	Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.
GO:0106363	protein-cysteine methyltransferase activity	molecular_function	Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein].
GO:0106364	4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity	molecular_function	4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].
GO:0106365	beta-carotene isomerase activity	molecular_function	Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.
GO:0106366	guanosine kinase activity	molecular_function	Catalysis of the reaction: ATP + guanosine = ADP + GMP.
GO:0106367	(deoxy)nucleoside phosphate kinase activity, dGTP as phosphate donor	molecular_function	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP.
GO:0106368	(deoxy)nucleoside phosphate kinase activity, dTTP as phosphate donor	molecular_function	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP.
GO:0106369	(deoxy)nucleoside phosphate kinase activity, GTP as phosphate donor	molecular_function	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP.
GO:0106370	protein-L-histidine N-pros-methyltransferase activity	molecular_function	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.
GO:0106371	fluorescent chlorophyll catabolite monooxygenase (deformylase) activity	molecular_function	Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.
GO:0106372	primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity	molecular_function	Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.
GO:0106373	3-deoxyglucosone dehydrogenase activity	molecular_function	Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD+ = 2-dehydro-3-deoxy-D-gluconate + 2 H+ + NADH.
GO:0106375	deoxynucleoside triphosphate hydrolase activity	molecular_function	Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.
GO:0106376	2-hydroxyphytanoyl-CoA lyase activity	molecular_function	Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.
GO:0106377	2-hydroxy-ATP hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + H+ + diphosphate.
GO:0106378	2-hydroxy-dATP hydrolase activity	molecular_function	Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + H+ + diphosphate.
GO:0106379	8-oxo-(d)RTP hydrolase activity	molecular_function	Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.
GO:0106380	purine ribonucleotide salvage	biological_process	Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis.
GO:0106381	purine deoxyribonucleotide salvage	biological_process	Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.
GO:0106383	dAMP salvage	biological_process	Any process which produces a dAMP from derivatives of it, without de novo synthesis.
GO:0106384	dGMP salvage	biological_process	Any process which produces a dGMP from derivatives of it, without de novo synthesis.
GO:0106385	dIMP salvage	biological_process	Any process which produces a dIMP from derivatives of it, without de novo synthesis.
GO:0106386	(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity	molecular_function	Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH.
GO:0106387	'de novo' GMP biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate.
GO:0106388	18S rRNA aminocarboxypropyltransferase activity	molecular_function	Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine.
GO:0106389	ecdysteroid 22-kinase activity	molecular_function	Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+.
GO:0106391	bI4 intron splicing complex	cellular_component	A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.
GO:0106392	bI3 intron splicing complex	cellular_component	Aprotein complex required for the splicing of intron 3 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI3 (which derives from one of the products of the splicing), the MRS1 cofactor and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.
GO:0106393	regulation of palmitic acid catabolic process	biological_process	Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process.
GO:0106394	negative regulation of palmitic acid catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a palmitic acid catabolic process.
GO:0106395	positive regulation of palmitic acid catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of a palmitic acid catabolic process.
GO:0106396	regulation of R7 cell fate commitment	biological_process	Any process that modulates the frequency, rate or extent of R7 cell fate commitment.
GO:0106397	positive regulation of R7 cell fate commitment	biological_process	Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment.
GO:0106398	negative regulation of R7 cell fate commitment	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment.
GO:0106399	acyl-coenzyme A diphosphatase activity	molecular_function	Catalysis of the reaction: an acyl-CoA + H2O = adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H+.
GO:0106400	double-strand break repair via transcription-associated homologous recombination	biological_process	A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair.
GO:0106402	Lewis x epitope biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.
GO:0106405	isoprenoid diphosphate phosphatase activity	molecular_function	Catalysis of the dephosphorylation of isoprenoid diphosphates.
GO:0106407	Glc2Man9GlcNAc2 oligosaccharide glucosidase activity	molecular_function	Catalysis of the reaction: Glc(2)Man(9)GlcNAc(2)-[protein] + H2O = GlcMan(9)GlcNAc(2)-[protein] + beta-D-glucopyranose.
GO:0106408	diadenylate cyclase activity	molecular_function	Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.
GO:0106409	cyclic-di-AMP phosphodiesterase activity	molecular_function	Catalysis of the reaction: 3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'-5')-adenosine + H+.
GO:0106410	box C/D RNA 5'-end processing	biological_process	Any process involved in forming the mature 5' end of a box C/D RNA molecule.
GO:0106411	XMP 5'-nucleosidase activity	molecular_function	Catalysis of the reaction: 5'XMP + H20 = phosphate + xanthosine.
GO:0106413	RNA dihydrouridine synthase activity	molecular_function	Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.
GO:0106414	mRNA dihydrouridine synthase activity	molecular_function	Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+.
GO:0106415	muramoyltetrapeptide carboxypeptidase activity	molecular_function	GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H2O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.
GO:0106417	dopaminechrome tautomerase activity	molecular_function	Catalysis of the reaction: dopaminechrome = 5,6-dihydroxyindole.
GO:0106418	UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity	molecular_function	Catalysis of the reaction: ATP + UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate.
GO:0106419	NAD-dependent protein lipoamidase activity	molecular_function	Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0106420	NAD-dependent protein biotinidase activity	molecular_function	Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0106421	L-glutamate:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamate(out) + H+(in) = L-glutamate(in) + H+(out).
GO:0106422	carotenoid isomerooxygenase activity	molecular_function	Catalysis of the reaction: Zeaxanthin + O2 <=> (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal.
GO:0106423	tubulin-tyrosine carboxypeptidase	molecular_function	Catalysis of the reaction: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine.
GO:0106425	3,4-dihydroxyphenylacetaldehyde synthase activity	molecular_function	Catalysis of the reaction: L-dopa + O2 + H2O + H+ <=> 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.
GO:0106426	regulation of kainate selective glutamate receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of tge kainate selective glutamate receptor signaling pathway.
GO:0106427	negative regulation of kainate selective glutamate receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
GO:0106428	positive regulation of kainate selective glutamate receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
GO:0106429	11-cis-retinol dehydrogenase	molecular_function	Catalysis of the reaction:11-cis-retinol-[retinal-binding-protein] + NAD+ <=> 11-cis-retinal-[retinol-binding-protein] + NADH.
GO:0106430	dihydroorotate dehydrogenase (quinone) activity	molecular_function	(S)-dihydroorotate + a quinone = orotate + a quinol.
GO:0106431	N6-methyl-(d)ATP hydrolase activity	molecular_function	Catalysis of the reaction N6-methyl-(d)ATP + H2O = N6-methyl-(d)AMP + diphosphate + H+.
GO:0106432	queuosine nucleosidase activity	molecular_function	Catalysis of the reaction: a N-D-queuosine + H2O = queuine + D-ribose.
GO:0106433	O6-methyl-dGTP hydrolase activity	molecular_function	Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+.
GO:0106434	retinal isomerization	biological_process	The reactions involved in isomerization of all trans to all cis retnal.
GO:0106435	carboxylesterase activity	molecular_function	Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H(+).
GO:0106436	glutathione-dependent sulfide quinone oxidoreductase activity	molecular_function	Catalysis of the reaction: a quinone + glutathione + H(+) + hydrogen sulfide <=> a quinol + S-sulfanylglutathione.
GO:0106437	protein-glutamic acid ligase activity, initiating	molecular_function	Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H(+) + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate.
GO:0106438	protein-glutamic acid ligase activity, elongating	molecular_function	Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate.
GO:0106439	L-lysine:L-arginine antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out).
GO:0110001	toxin-antitoxin complex	cellular_component	A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.
GO:0110002	regulation of tRNA methylation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.
GO:0110003	regulation of tRNA C5-cytosine methylation	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.
GO:0110004	positive regulation of tRNA methylation	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA methylation.
GO:0110005	positive regulation of tRNA C5-cytosine methylation	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.
GO:0110008	ncRNA deadenylation	biological_process	Shortening of the poly(A) tail of a nuclear-transcribed ncRNA.
GO:0110009	formin-nucleated actin cable organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.
GO:0110010	basolateral protein secretion	biological_process	The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.
GO:0110011	regulation of basement membrane organization	biological_process	Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.
GO:0110012	protein localization to P-body	biological_process	Any process in which a protein is transported to, or maintained at, a P-body.
GO:0110013	positive regulation of aggregation involved in sorocarp development	biological_process	Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
GO:0110014	negative regulation of aggregation involved in sorocarp development	biological_process	Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
GO:0110015	positive regulation of elastin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
GO:0110016	B-WICH complex	cellular_component	A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself.
GO:0110017	cap-independent translational initiation of linear mRNA	biological_process	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.
GO:0110018	cap-independent translational initiation of circular RNA	biological_process	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.
GO:0110019	IRES-dependent translational initiation of circular RNA	biological_process	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.
GO:0110020	regulation of actomyosin structure organization	biological_process	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.
GO:0110021	cardiac muscle myoblast proliferation	biological_process	The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
GO:0110022	regulation of cardiac muscle myoblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.
GO:0110023	negative regulation of cardiac muscle myoblast proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.
GO:0110024	positive regulation of cardiac muscle myoblast proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.
GO:0110025	DNA strand resection involved in replication fork processing	biological_process	The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.
GO:0110026	regulation of DNA strand resection involved in replication fork processing	biological_process	Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.
GO:0110027	negative regulation of DNA strand resection involved in replication fork processing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.
GO:0110028	positive regulation of mitotic spindle organization	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
GO:0110029	negative regulation of meiosis I	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
GO:0110030	regulation of G2/MI transition of meiotic cell cycle	biological_process	Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
GO:0110031	negative regulation of G2/MI transition of meiotic cell cycle	biological_process	Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
GO:0110032	positive regulation of G2/MI transition of meiotic cell cycle	biological_process	Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
GO:0110033	regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
GO:0110034	negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.
GO:0110035	rDNA spacer replication fork barrier binding, bending	molecular_function	The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0110036	C2 domain binding	molecular_function	Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.
GO:0110037	regulation of nematode male tail tip morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.
GO:0110038	negative regulation of nematode male tail tip morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.
GO:0110039	positive regulation of nematode male tail tip morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.
GO:0110040	pharynx morphogenesis	biological_process	The process in which the anatomical structures of the pharynx are generated and organized.
GO:0110041	regulation of pharynx morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.
GO:0110042	negative regulation of pharynx morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.
GO:0110043	positive regulation of pharynx morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.
GO:0110044	regulation of cell cycle switching, mitotic to meiotic cell cycle	biological_process	Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
GO:0110045	negative regulation of cell cycle switching, mitotic to meiotic cell cycle	biological_process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
GO:0110046	signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle	biological_process	A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle.
GO:0110050	deaminated glutathione amidase activity	molecular_function	Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.
GO:0110051	metabolite repair	biological_process	A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
GO:0110052	toxic metabolite repair	biological_process	A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
GO:0110053	regulation of actin filament organization	biological_process	Any process that modulates the frequency, rate or extent of actin filament organization.
GO:0110054	regulation of actin filament annealing	biological_process	Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
GO:0110055	negative regulation of actin filament annealing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
GO:0110056	positive regulation of actin filament annealing	biological_process	Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
GO:0110057	regulation of blood vessel endothelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.
GO:0110058	positive regulation of blood vessel endothelial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.
GO:0110059	negative regulation of blood vessel endothelial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.
GO:0110061	regulation of angiotensin-activated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.
GO:0110062	negative regulation of angiotensin-activated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.
GO:0110063	positive regulation of angiotensin-activated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.
GO:0110064	lncRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.
GO:0110065	regulation of interphase mitotic telomere clustering	biological_process	Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.
GO:0110066	negative regulation of interphase mitotic telomere clustering	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.
GO:0110067	ammonium transmembrane transporter complex	cellular_component	High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.
GO:0110068	glucosylglycerate phosphorylase activity	molecular_function	Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate.
GO:0110069	syncytial embryo cellularization	biological_process	The separation of a syncytial embryo into individual cells.
GO:0110070	cellularization cleavage furrow	cellular_component	A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.
GO:0110071	cellularization cleavage furrow invagination front	cellular_component	The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.
GO:0110072	apical constriction involved in ventral furrow formation	biological_process	The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
GO:0110073	regulation of apical constriction involved in ventral furrow formation	biological_process	Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.
GO:0110074	positive regulation of apical constriction involved in ventral furrow formation	biological_process	Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.
GO:0110075	regulation of ferroptosis	biological_process	Any process that modulates the frequency, rate or extent of ferroptosis.
GO:0110076	negative regulation of ferroptosis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis.
GO:0110077	vesicle-mediated intercellular transport	biological_process	A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.
GO:0110078	TTT complex	cellular_component	A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).
GO:0110079	regulation of placenta blood vessel development	biological_process	Any process that modulates the frequency, rate or extent of placenta blood vessel development.
GO:0110080	positive regulation of placenta blood vessel development	biological_process	Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.
GO:0110081	negative regulation of placenta blood vessel development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.
GO:0110082	regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
GO:0110083	positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
GO:0110084	negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
GO:0110085	mitotic actomyosin contractile ring	cellular_component	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.
GO:0110086	meiotic actomyosin contractile ring	cellular_component	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis.
GO:0110088	hippocampal neuron apoptotic process	biological_process	Any apoptotic process that occurs in a hippocampal neuron.
GO:0110089	regulation of hippocampal neuron apoptotic process	biological_process	Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.
GO:0110090	positive regulation of hippocampal neuron apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.
GO:0110091	negative regulation of hippocampal neuron apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.
GO:0110092	nucleus leading edge	cellular_component	The area of a motile nucleus closest to the direction of movement.
GO:0110093	nucleus lagging edge	cellular_component	The area of a motile nucleus furthest from the direction of movement.
GO:0110094	polyphosphate-mediated signaling	biological_process	Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.
GO:0110095	cellular detoxification of aldehyde	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0110096	cellular response to aldehyde	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.
GO:0110097	regulation of calcium import into the mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.
GO:0110098	positive regulation of calcium import into the mitochondrion	biological_process	Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.
GO:0110099	negative regulation of calcium import into the mitochondrion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.
GO:0110100	spindle pole body separation	biological_process	The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.
GO:0110101	L-valine transmembrane import into vacuole	biological_process	The directed movement of L-valine into the vacuole across the vacuolar membrane.
GO:0110102	ribulose bisphosphate carboxylase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.
GO:0110103	RNA polymerase II termination complex	cellular_component	A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.
GO:0110104	mRNA alternative polyadenylation	biological_process	The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
GO:0110105	mRNA cleavage and polyadenylation specificity factor complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.
GO:0110107	regulation of imaginal disc-derived wing vein specification	biological_process	Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.
GO:0110108	positive regulation of imaginal disc-derived wing vein specification	biological_process	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.
GO:0110109	negative regulation of imaginal disc-derived wing vein specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.
GO:0110110	positive regulation of animal organ morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.
GO:0110111	negative regulation of animal organ morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.
GO:0110112	regulation of lipid transporter activity	biological_process	Any process that modulates the frequency, rate, or extent of lipid transporter activity.
GO:0110113	positive regulation of lipid transporter activity	biological_process	Any process that increases the frequency, rate, or extent of lipid transporter activity.
GO:0110114	negative regulation of lipid transporter activity	biological_process	Any process that decreases the frequency, rate, or extent of lipid transporter activity.
GO:0110115	Cdr2 medial cortical node complex	cellular_component	A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.
GO:0110116	regulation of compound eye photoreceptor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.
GO:0110117	positive regulation of compound eye photoreceptor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.
GO:0110118	negative regulation of compound eye photoreceptor cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.
GO:0110119	positive regulation of very-low-density lipoprotein particle clearance	biological_process	Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.
GO:0110120	gamma-tubulin complex localization to nuclear side of mitotic spindle pole body	biological_process	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.
GO:0110121	gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body	biological_process	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.
GO:0110122	myotube cell migration	biological_process	The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.
GO:0110123	regulation of myotube cell migration	biological_process	Any process that modulates the frequency, rate or extent of myotube cell migration.
GO:0110124	positive regulation of myotube cell migration	biological_process	Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.
GO:0110125	negative regulation of myotube cell migration	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.
GO:0110126	phloem loading	biological_process	The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
GO:0110127	phloem unloading	biological_process	The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
GO:0110128	phloem sucrose unloading	biological_process	The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
GO:0110129	SHREC2 complex	cellular_component	A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.
GO:0110130	ribitol-5-phosphatase activity	molecular_function	Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.
GO:0110131	Aim21-Tda2 complex	cellular_component	A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.
GO:0110134	meiotic drive	biological_process	A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.
GO:0110135	Norrin signaling pathway	biological_process	The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.
GO:0110136	protein-RNA complex remodeling	biological_process	The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.
GO:0110137	regulation of imaginal disc-derived leg joint morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.
GO:0110138	positive regulation of imaginal disc-derived leg joint morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
GO:0110139	negative regulation of imaginal disc-derived leg joint morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
GO:0110140	flagellum attachment zone organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.
GO:0110141	L-glutamate import into mitochondrion	biological_process	The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.
GO:0110142	ubiquinone biosynthesis complex	cellular_component	The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K.
GO:0110143	magnetosome	cellular_component	A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.
GO:0110145	magnetosome lumen	cellular_component	The volume enclosed by the membrane of a magnetosome.
GO:0110146	magnetosome membrane	cellular_component	The lipid bilayer surrounding a magnetosome.
GO:0110147	protein maturation by nickel ion transfer	biological_process	A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.
GO:0110152	RNA NAD-cap (NAD-forming) hydrolase activity	molecular_function	Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.
GO:0110153	RNA NAD-cap (NMN-forming) hydrolase activity	molecular_function	Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.
GO:0110154	RNA decapping	biological_process	Cleavage of the 5'-cap of an RNA.
GO:0110155	NAD-cap decapping	biological_process	Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.
GO:0110156	methylguanosine-cap decapping	biological_process	Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.
GO:0110157	reelin complex	cellular_component	An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.
GO:0110158	calpain complex	cellular_component	A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.
GO:0110159	regulation of mitotic spindle formation (spindle phase one)	biological_process	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
GO:0110160	negative regulation of mitotic spindle formation (spindle phase one)	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
GO:0110161	positive regulation of mitotic spindle formation (spindle phase one)	biological_process	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
GO:0110162	regulation of mitotic spindle elongation (spindle phase three)	biological_process	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
GO:0110163	negative regulation of mitotic spindle elongation (spindle phase three)	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
GO:0110164	positive regulation of mitotic spindle elongation (spindle phase three)	biological_process	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
GO:0110165	cellular anatomical entity	cellular_component	A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.
GO:0110166	DNA synthesis involved in mitochondrial DNA replication	biological_process	Any DNA biosynthetic process that is involved in mitochondrial DNA replication.
GO:0120001	apical plasma membrane urothelial plaque	cellular_component	A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.
GO:0120002	fusiform vesicle	cellular_component	A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.
GO:0120003	hinge region between urothelial plaques of apical plasma membrane	cellular_component	A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.
GO:0120006	regulation of glutamatergic neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.
GO:0120007	negative regulation of glutamatergic neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.
GO:0120008	positive regulation of glutamatergic neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.
GO:0120009	intermembrane lipid transfer	biological_process	The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
GO:0120010	intermembrane phospholipid transfer	biological_process	The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.
GO:0120011	intermembrane sterol transfer	biological_process	The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
GO:0120012	intermembrane sphingolipid transfer	biological_process	The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
GO:0120013	lipid transfer activity	molecular_function	Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.
GO:0120014	phospholipid transfer activity	molecular_function	Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120015	sterol transfer activity	molecular_function	Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120016	sphingolipid transfer activity	molecular_function	Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120017	ceramide transfer activity	molecular_function	Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120019	phosphatidylcholine transfer activity	molecular_function	Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120020	cholesterol transfer activity	molecular_function	Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120021	oxysterol transfer activity	molecular_function	Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:0120022	glucagon family peptide binding	molecular_function	Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).
GO:0120023	somatostatin binding	molecular_function	Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.
GO:0120025	plasma membrane bounded cell projection	cellular_component	A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GO:0120026	host cell uropod	cellular_component	A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
GO:0120027	regulation of osmosensory signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.
GO:0120028	negative regulation of osmosensory signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.
GO:0120029	proton export across plasma membrane	biological_process	The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.
GO:0120030	positive regulation of cilium beat frequency involved in ciliary motility	biological_process	Any process that activates or increases the frequency of cilium beating involved in ciliary motility.
GO:0120031	plasma membrane bounded cell projection assembly	biological_process	Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GO:0120032	regulation of plasma membrane bounded cell projection assembly	biological_process	Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	biological_process	Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GO:0120035	regulation of plasma membrane bounded cell projection organization	biological_process	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
GO:0120036	plasma membrane bounded cell projection organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
GO:0120039	plasma membrane bounded cell projection morphogenesis	biological_process	The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.
GO:0120040	regulation of macrophage proliferation	biological_process	Any process that modulates the frequency, rate or extent of macrophage proliferation.
GO:0120041	positive regulation of macrophage proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage proliferation.
GO:0120042	negative regulation of macrophage proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.
GO:0120043	stereocilium shaft	cellular_component	The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.
GO:0120044	stereocilium base	cellular_component	The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.
GO:0120045	stereocilium maintenance	biological_process	The organization process that preserves a stereocilium in a stable functional or structural state.
GO:0120046	regulation of protein localization to medial cortical node	biological_process	Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.
GO:0120047	positive regulation of protein localization to medial cortical node	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.
GO:0120048	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA.
GO:0120049	snRNA (adenine-N6)-methylation	biological_process	The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.
GO:0120053	ribitol beta-1,4-xylosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.
GO:0120054	intestinal motility	biological_process	Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).
GO:0120055	small intestinal transit	biological_process	Migration of ingested material along the length of the small intestine.
GO:0120056	large intestinal transit	biological_process	Migration of ingested material along the length of the large intestine.
GO:0120057	regulation of small intestinal transit	biological_process	Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
GO:0120058	positive regulation of small intestinal transit	biological_process	Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
GO:0120059	negative regulation of small intestinal transit	biological_process	Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
GO:0120060	regulation of gastric emptying	biological_process	Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
GO:0120061	negative regulation of gastric emptying	biological_process	Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
GO:0120062	positive regulation of gastric emptying	biological_process	Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
GO:0120063	stomach smooth muscle contraction	biological_process	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.
GO:0120064	stomach pylorus smooth muscle contraction	biological_process	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.
GO:0120065	pyloric antrum smooth muscle contraction	biological_process	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.
GO:0120066	pyloric canal smooth muscle contraction	biological_process	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.
GO:0120067	pyloric sphincter smooth muscle contraction	biological_process	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.
GO:0120068	regulation of stomach fundus smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.
GO:0120069	positive regulation of stomach fundus smooth muscle contraction	biological_process	Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.
GO:0120070	negative regulation of stomach fundus smooth muscle contraction	biological_process	Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.
GO:0120071	regulation of pyloric antrum smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
GO:0120072	positive regulation of pyloric antrum smooth muscle contraction	biological_process	Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
GO:0120073	negative regulation of pyloric antrum smooth muscle contraction	biological_process	Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
GO:0120074	regulation of endocardial cushion cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.
GO:0120075	positive regulation of endocardial cushion cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.
GO:0120076	negative regulation of endocardial cushion cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.
GO:0120077	angiogenic sprout fusion	biological_process	The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.
GO:0120078	cell adhesion involved in sprouting angiogenesis	biological_process	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.
GO:0120082	smooth endoplasmic reticulum cisterna	cellular_component	A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.
GO:0120083	rough endoplasmic reticulum cisterna	cellular_component	A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.
GO:0120084	endothelial tip cell filopodium assembly	biological_process	The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.
GO:0120086	(3S)-(+)-asterisca-2(9),6-diene synthase activity	molecular_function	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene.
GO:0120091	jasmonic acid hydrolase	molecular_function	Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid.
GO:0120092	crotonyl-CoA hydratase activity	molecular_function	Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
GO:0120093	regulation of peptidyl-lysine crotonylation	biological_process	Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.
GO:0120094	negative regulation of peptidyl-lysine crotonylation	biological_process	Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.
GO:0120095	vacuole-isolation membrane contact site	cellular_component	An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.
GO:0120097	glycosylphosphatidylinositol-mannosyltransferase II complex	cellular_component	A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.
GO:0120098	procentriole	cellular_component	A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.
GO:0120099	procentriole replication complex	cellular_component	A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.
GO:0120100	bacterial-type flagellum motor	cellular_component	A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation.
GO:0120101	bacterial-type flagellum stator complex	cellular_component	A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species.
GO:0120102	bacterial-type flagellum secretion apparatus	cellular_component	A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.
GO:0120103	centriolar subdistal appendage	cellular_component	A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.
GO:0120104	mitotic actomyosin contractile ring, proximal layer	cellular_component	The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.
GO:0120105	mitotic actomyosin contractile ring, intermediate layer	cellular_component	The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.
GO:0120106	mitotic actomyosin contractile ring, distal actin filament layer	cellular_component	The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.
GO:0120107	bacterial-type flagellum rotor complex	cellular_component	The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.
GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase	molecular_function	Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H2O = (DNA)-3'-phosphate + GMP.
GO:0120109	mitotic telomere clustering and tethering at nuclear periphery	biological_process	The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.
GO:0120110	interphase mitotic telomere clustering	biological_process	The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.
GO:0120111	neuron projection cytoplasm	cellular_component	All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.
GO:0120112	UDP-glucose transmembrane transport into endoplasmic reticulum	biological_process	The directed movement of UDP-glucose from cytosol to endoplasmic reticulum.
GO:0120113	cytoplasm to vacuole transport by the NVT pathway	biological_process	A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe.
GO:0120114	Sm-like protein family complex	cellular_component	A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.
GO:0120115	Lsm2-8 complex	cellular_component	A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.
GO:0120116	glucagon processing	biological_process	The formation of mature glucagon by proteolysis of the precursor proglucagon.
GO:0120117	T cell meandering migration	biological_process	The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).
GO:0120118	flagella connector	cellular_component	A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.
GO:0120119	flagellum attachment zone	cellular_component	A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.
GO:0120120	bilobe structure	cellular_component	A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).
GO:0120121	tripartite attachment complex	cellular_component	A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body.
GO:0120122	prolactin metabolic process	biological_process	The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals.
GO:0120123	ubiquitin activating enzyme complex	cellular_component	A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
GO:0120124	membrane fusion priming complex	cellular_component	A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes.
GO:0120125	PNGase complex	cellular_component	A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
GO:0120126	response to copper ion starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.
GO:0120127	response to zinc ion starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.
GO:0120132	positive regulation of apoptotic process in bone marrow cell	biological_process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.
GO:0120133	negative regulation of actin cortical patch assembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches.
GO:0120134	proximal portion of axoneme	cellular_component	The portion of the axoneme that is close to the base of the cilium.
GO:0120135	distal portion of axoneme	cellular_component	The portion of the axoneme that is close to the tip of the cilium.
GO:0120136	dUMP kinase activity	molecular_function	Catalysis of the reaction: ATP + dUMP = ADP + dUDP.
GO:0120137	positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	biological_process	Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.
GO:0120138	regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.
GO:0120139	positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.
GO:0120140	negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.
GO:0120141	regulation of ecdysone receptor-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway.
GO:0120142	positive regulation of ecdysone receptor-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.
GO:0120143	negative regulation of ecdysone receptor-mediated signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.
GO:0120145	protein localization to basal ectoplasmic specialization	biological_process	A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.
GO:0120146	sulfatide binding	molecular_function	Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.
GO:0120147	formylglycine-generating oxidase activity	molecular_function	Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.
GO:0120148	host cell centrosome	cellular_component	A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
GO:0120149	host cell peroxisome	cellular_component	A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
GO:0120150	regulation of mitotic actomyosin contractile ring disassembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.
GO:0120151	positive regulation of mitotic actomyosin contractile ring disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.
GO:0120152	calcium-dependent outer dynein arm binding	molecular_function	Binding to an outer dynein arm in the presence of calcium.
GO:0120153	calcium-dependent carbohydrate binding	molecular_function	Binding to a carbohydrate in the presence of calcium.
GO:0120154	negative regulation of ERBB4 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.
GO:0120155	MIH complex	cellular_component	A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.
GO:0120157	PAR polarity complex	cellular_component	A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.
GO:0120158	positive regulation of collagen catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
GO:0120159	rRNA pseudouridine synthase activity	molecular_function	Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
GO:0120160	intraciliary transport particle A binding	molecular_function	Binding to an intraciliary transport particle A (IFT A) complex.
GO:0120161	regulation of cold-induced thermogenesis	biological_process	Any process that modulates the frequency, rate or extent of cold-induced thermogenesis.
GO:0120162	positive regulation of cold-induced thermogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
GO:0120163	negative regulation of cold-induced thermogenesis	biological_process	Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
GO:0120164	conidium germination	biological_process	The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination.
GO:0120165	perithecium development	biological_process	The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.
GO:0120166	protoperithecium formation	biological_process	The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium.
GO:0120168	detection of hot stimulus involved in thermoception	biological_process	The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception.
GO:0120169	detection of cold stimulus involved in thermoception	biological_process	The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception.
GO:0120170	intraciliary transport particle B binding	molecular_function	Binding to an intraciliary transport particle B (IFT B) complex.
GO:0120171	Cdc24p-Far1p-Gbetagamma complex	cellular_component	A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit).
GO:0120174	stress-induced homeostatically regulated protein degradation pathway	biological_process	A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.
GO:0120175	regulation of torso signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the torso signaling pathway.
GO:0120176	positive regulation of torso signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the torso signaling pathway.
GO:0120177	negative regulation of torso signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.
GO:0120178	steroid hormone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
GO:0120179	adherens junction disassembly	biological_process	The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:0120180	cell-substrate junction disassembly	biological_process	The disaggregation of a cell-substrate junction into its constituent components.
GO:0120181	focal adhesion disassembly	biological_process	The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity.
GO:0120182	regulation of focal adhesion disassembly	biological_process	Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.
GO:0120183	positive regulation of focal adhesion disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.
GO:0120184	negative regulation of focal adhesion disassembly	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.
GO:0120185	MBF transcription complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex.
GO:0120186	negative regulation of protein localization to chromatin	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.
GO:0120187	positive regulation of protein localization to chromatin	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.
GO:0120188	regulation of bile acid secretion	biological_process	Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.
GO:0120189	positive regulation of bile acid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.
GO:0120190	negative regulation of bile acid secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.
GO:0120191	negative regulation of termination of RNA polymerase II transcription	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.
GO:0120192	tight junction assembly	biological_process	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
GO:0120193	tight junction organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
GO:0120194	regulation of anther dehiscence	biological_process	Any process involved in the dehiscence of an anther to release the pollen grains contained within it.
GO:0120195	positive regulation of anther dehiscence	biological_process	Any process that activates or increases the frequency, rate or extent of anther dehiscence.
GO:0120196	negative regulation of anther dehiscence	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.
GO:0120197	mucociliary clearance	biological_process	The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways.
GO:0120198	positive regulation of imaginal disc-derived wing size	biological_process	Any process that increases the size of an imaginal disc-derived wing.
GO:0120199	cone photoreceptor outer segment	cellular_component	The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.
GO:0120200	rod photoreceptor outer segment	cellular_component	The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.
GO:0120201	cone photoreceptor disc membrane	cellular_component	Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane.
GO:0120202	rod photoreceptor disc membrane	cellular_component	Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment.
GO:0120203	rod photoreceptor disc lumen	cellular_component	The volume enclosed by the membrane of a rod photoreceptor cell disc membrane.
GO:0120204	methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity	molecular_function	Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.
GO:0120205	photoreceptor proximal connecting cilium	cellular_component	The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR.
GO:0120206	photoreceptor distal connecting cilium	cellular_component	The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability.
GO:0120207	endocytosis, site selection	biological_process	The process of selecting and or marking the position where endocytosis will occur.
GO:0120208	telodendria	cellular_component	Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons.
GO:0120209	cone telodendria	cellular_component	Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.
GO:0120210	rod telodendria	cellular_component	Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.
GO:0120211	proacrosomal vesicle fusion	biological_process	Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.
GO:0120212	sperm head-tail coupling apparatus	cellular_component	A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.
GO:0120213	regulation of histidine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of histidine biosynthetic process.
GO:0120214	negative regulation of histidine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.
GO:0120215	positive regulation of histidine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.
GO:0120216	matrilin complex	cellular_component	A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer.
GO:0120217	DNA gyrase complex	cellular_component	A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).
GO:0120218	host interaction involved in quorum sensing	biological_process	A quorum sensing process that is modulated by some interaction with a host cell or organism.
GO:0120219	subapical part of cell	cellular_component	The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina.
GO:0120220	basal body patch	cellular_component	The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster.
GO:0120221	maintenance of ciliary planar beating movement pattern	biological_process	Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.
GO:0120222	regulation of blastocyst development	biological_process	Any process that modulates the frequency, rate or extent of blastocyst development.
GO:0120223	larynx morphogenesis	biological_process	The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.
GO:0120224	larynx development	biological_process	The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.
GO:0120225	coenzyme A binding	molecular_function	Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
GO:0120226	succinyl-CoA binding	molecular_function	Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.
GO:0120227	acyl-CoA binding	molecular_function	Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.
GO:0120228	outer dynein arm docking complex	cellular_component	A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules.
GO:0120229	protein localization to motile cilium	biological_process	A process in which a protein is transported to, or maintained in, a location within a motile cilium.
GO:0120230	recombinase activator activity	molecular_function	Binds to and increases the activity of a recombinase.
GO:0120231	DNA recombinase auxiliary factor complex	cellular_component	A protein complex that binds to a recombinase and incrseases its activity.
GO:0120232	prenyl-FMNH2 biosynthetic process	biological_process	The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.
GO:0120233	prenyl-FMNH2 binding	molecular_function	Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.
GO:0120234	stereocilium coat	cellular_component	A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle.
GO:0120235	regulation of post-translational protein targeting to membrane, translocation	biological_process	Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.
GO:0120236	negative regulation of post-translational protein targeting to membrane, translocation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.
GO:0120237	terminal acetylenic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
GO:0120238	sperm glycocalyx	cellular_component	The carbohydrate rich layer at the outermost periphery of a sperm cell.
GO:0120239	vascular endothelial glycocalyx	cellular_component	The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated.
GO:0120240	platelet glycocalyx	cellular_component	The carbohydrate rich layer at the outermost periphery of a platelet.
GO:0120241	2-iminobutanoate/2-iminopropanoate deaminase	molecular_function	Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.
GO:0120242	2-iminobutanoate deaminase activity	molecular_function	Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+).
GO:0120243	2-iminopropanoate deaminase activity	molecular_function	Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate.
GO:0120244	terminal acetylenic compound metabolic process	biological_process	The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
GO:0120245	terminal acetylenic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
GO:0120246	acetylenic compound metabolic process	biological_process	The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
GO:0120247	acetylenic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
GO:0120248	acetylenic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
GO:0120249	lateral wall of outer hair cell	cellular_component	The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae.
GO:0120250	fatty acid omega-hydroxylase activity	molecular_function	Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
GO:0120251	hydrocarbon biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.
GO:0120252	hydrocarbon metabolic process	biological_process	The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.
GO:0120253	hydrocarbon catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.
GO:0120254	olefinic compound metabolic process	biological_process	The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
GO:0120255	olefinic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
GO:0120256	olefinic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
GO:0120257	peptidyl-threonine acetylation	biological_process	The acetylation of peptidyl-threonine.
GO:0120258	peptidyl-threonine O-acetylation	biological_process	The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine.
GO:0120259	7SK snRNP	cellular_component	A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb.
GO:0120260	ciliary microtubule quartet	cellular_component	A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape.
GO:0120261	regulation of heterochromatin organization	biological_process	Any process that modulates the frequency, rate, extent or location of heterochromatin organization.
GO:0120262	negative regulation of heterochromatin organization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization.
GO:0120263	positive regulation of heterochromatin organization	biological_process	Any process that activates or increases the frequency, rate or extent of heterochromatin organization.
GO:0120264	regulation of chromosome attachment to the nuclear envelope	biological_process	Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.
GO:0120265	negative regulation of chromosome attachment to the nuclear envelope	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.
GO:0120266	positive regulation of chromosome attachment to the nuclear envelope	biological_process	Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.
GO:0120267	pellicular membrane	cellular_component	The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles.
GO:0120268	paraflagellar rod assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme.
GO:0120269	ciliary centrin arm	cellular_component	A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.
GO:0120270	regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	biological_process	Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
GO:0120271	negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
GO:0120272	positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	biological_process	Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
GO:0120273	ciliary centrin arm assembly	biological_process	The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.
GO:0120274	virus coreceptor activity	molecular_function	Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
GO:0120275	cerebral blood circulation	biological_process	The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.
GO:0120276	regulation of cerebral blood circulation	biological_process	Any process that modulates the frequency, rate or extent of cerebral blood circulation.
GO:0120277	positive regulation of cerebral blood circulation	biological_process	Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.
GO:0120278	negative regulation of cerebral blood circulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.
GO:0120279	Z granule	cellular_component	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.
GO:0120280	ciliary pro-basal body	cellular_component	The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.
GO:0120281	autolysosome membrane	cellular_component	A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.
GO:0120282	autolysosome lumen	cellular_component	The volume that is enclosed within the autolysosome single-membrane.
GO:0120283	protein serine/threonine kinase binding	molecular_function	Binding to a protein serine/threonine kinase.
GO:0120284	tryptophan binding	molecular_function	Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid.
GO:0120285	tyrosine sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine.
GO:0120286	tryptophan sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan.
GO:0120290	stalled replication fork localization to nuclear periphery	biological_process	A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.
GO:0120291	negative regulation of mitotic recombination-dependent replication fork processing	biological_process	Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.
GO:0120292	positive regulation of mitotic recombination-dependent replication fork processing	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.
GO:0120293	dynein axonemal particle	cellular_component	An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.
GO:0120294	peptide serotonyltransferase activity	molecular_function	Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+).
GO:0120295	histone serotonyltransferase activity	molecular_function	Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+).
GO:0120296	peptide dopaminyltransferase activity	molecular_function	Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+).
GO:0120297	histone dopaminyltransferase activity	molecular_function	Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+).
GO:0120298	peptide noradrenalinyltransferase activity	molecular_function	Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+).
GO:0120299	peptide histaminyltransferase activity	molecular_function	Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].
GO:0120300	peptide lactyltransferase activity	molecular_function	Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[protein].
GO:0120301	histone lactyltransferase activity	molecular_function	Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[histone].
GO:0120302	background adaptation	biological_process	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.
GO:0120303	visually-mediated background adaptation	biological_process	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.
GO:0120304	integument-mediated background adaptation	biological_process	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.
GO:0120305	regulation of pigmentation	biological_process	Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.
GO:0120306	cellular response to actin cytoskeletal stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.
GO:0120307	Hechtian strand	cellular_component	An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.
GO:0120308	axonemal outer doublet assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.
GO:0120309	cilium attachment to cell body	biological_process	A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.
GO:0120310	amastigogenesis	biological_process	The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites.
GO:0120311	ciliary pro-basal body maturation	biological_process	A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.
GO:0120312	ciliary basal body segregation	biological_process	The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.
GO:0120313	regulation of oocyte karyosome formation	biological_process	Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0120314	negative regulation of oocyte karyosome formation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0120315	positive regulation of oocyte karyosome formation	biological_process	Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
GO:0120316	sperm flagellum assembly	biological_process	The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).
GO:0120317	sperm mitochondrial sheath assembly	biological_process	The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
GO:0120318	olfactory sociosexual communication	biological_process	The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system.
GO:0120319	long-chain fatty acid omega-1 hydroxylase activity	molecular_function	Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase.
GO:0120320	lateral pseudopodium retraction	biological_process	The myosin-based contraction and retraction of a lateral pseudopodium.
GO:0120321	nuclear envelope adjacent to nuclear pore complex	cellular_component	The region of the nuclear envelope situated in close proximity to a nuclear pore complex.
GO:0120322	lipid modification by small protein conjugation	biological_process	A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.
GO:0120323	lipid ubiquitination	biological_process	The process in which one or more ubiquitin groups are added to a lipid.
GO:0120324	procyclogenesis	biological_process	The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.
GO:0120325	NuRD complex binding	molecular_function	Binding to a NuRD complex.
GO:0120326	appressorium-mediated entry into host	biological_process	Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0120327	telopode	cellular_component	A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.
GO:0120328	ATP-dependent DNA (cytosine-5-)-methyltransferase activity	molecular_function	Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.
GO:0120329	protein localization to centriolar satellite	biological_process	A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.
GO:0120330	rixosome complex	cellular_component	A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.
GO:0120331	endothelial tube formation	biological_process	The developmental process pertaining to the initial formation of an endothelial tube.
GO:0120332	host-mediated regulation of oral microbiota composition	biological_process	The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth.
GO:0120333	radial spoke 1	cellular_component	The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is most proximal to the base of the cilium. Radial spoke 1 (RS1), similarly to radial spoke 2, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS1 is connected to the tail of the inner dynein arm a/d.
GO:0120334	radial spoke 2	cellular_component	The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is immediately distal to radial spoke 1 (RS1). Radial spoke 2 (RS2), similarly to RS1, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS2 is connected to the tail of the inner dynein arm c.
GO:0120335	radial spoke 3	cellular_component	Radial spoke 3 (RS3), when present, is the most distal of each group of radial spokes, whether grouped as triplets or doublets. RS3 has significantly different morphology and protein composition than RS1 and RS2 and also extends at a slant from the microtubule doublet, rather than perpendicularly like RS1 and RS2. In some organisms (e.g. Chlamydomonas and Sarcophaga bullata), RS3 is represented only as a stump attached to the A-microtubule lacking the rest of the stalk structure and entirely lacking the head structure.
GO:0120336	radial spoke head 1	cellular_component	The portion of the radial spoke 1 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
GO:0120337	radial spoke head 2	cellular_component	The portion of the radial spoke 2 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
GO:0120338	radial spoke head 3	cellular_component	The portion of the radial spoke 3 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
GO:0120339	radial spoke base	cellular_component	The short portion of the radial spoke that is directly anchored to the A microtubule of an axonemal microtubule doublet.
GO:0120340	radial spoke base 1	cellular_component	The short portion of the radial spoke 1 (RS1) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
GO:0120341	radial spoke base 2	cellular_component	The short portion of the radial spoke 2 (RS2) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
GO:0120342	radial spoke base 3	cellular_component	The short portion of the radial spoke 3 (RS3 )that is directly anchored to the A microtubule of an axonemal microtubule doublet.
GO:0120343	radial spoke neck	cellular_component	The radial spoke neck is a complex that connects the spoke stalk to the head.
GO:0140007	KICSTOR complex	cellular_component	A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2.
GO:0140009	L-aspartate import across plasma membrane	biological_process	The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140010	D-aspartate transmembrane transporter activity	molecular_function	Enables the transfer of D-aspartate from one side of a membrane to the other.
GO:0140013	meiotic nuclear division	biological_process	One of the two nuclear divisions that occur as part of the meiotic cell cycle.
GO:0140014	mitotic nuclear division	biological_process	A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
GO:0140018	regulation of cytoplasmic translational fidelity	biological_process	Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.
GO:0140020	DNA methyltransferase complex	cellular_component	A protein complex that possesses DNA methyltransferase activity.
GO:0140021	mitochondrial ADP transmembrane transport	biological_process	The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0140022	cnida	cellular_component	A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria.
GO:0140023	tRNA adenosine deamination to inosine	biological_process	The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.
GO:0140024	plus-end-directed endosome transport along mitotic spindle midzone microtubule	biological_process	The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination.
GO:0140025	contractile vacuole tethering involved in discharge	biological_process	The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.
GO:0140026	contractile vacuole dissociation from plasma membrane	biological_process	The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network.
GO:0140027	contractile vacuole localization	biological_process	The directed movement of the contractile vacuole to a specific location.
GO:0140028	pore formation during contractile vacuole discharge	biological_process	The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes.
GO:0140029	exocytic process	biological_process	The cellular processes that contribute to exocytosis.
GO:0140030	modification-dependent protein binding	molecular_function	Binding to a protein upon post-translation modification of the target protein.
GO:0140031	phosphorylation-dependent protein binding	molecular_function	Binding to a protein upon phosphorylation of the target protein.
GO:0140032	glycosylation-dependent protein binding	molecular_function	Binding to a protein upon glycosylation of the target protein.
GO:0140033	acetylation-dependent protein binding	molecular_function	Binding to a protein upon acetylation of the target protein.
GO:0140034	methylation-dependent protein binding	molecular_function	Binding to a protein upon methylation of the target protein.
GO:0140035	ubiquitination-like modification-dependent protein binding	molecular_function	Binding to a protein upon modification by a ubiquitin-like protein of the target protein.
GO:0140036	ubiquitin-dependent protein binding	molecular_function	Binding to a protein upon ubiquitination of the target protein.
GO:0140037	sumo-dependent protein binding	molecular_function	Binding to a protein upon sumoylation of the target protein.
GO:0140039	cell-cell adhesion in response to extracellular stimulus	biological_process	The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.
GO:0140040	mitochondrial polycistronic RNA processing	biological_process	The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.
GO:0140041	cellular detoxification of methylglyoxal	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. These may include chemical modification or transport of methylglyoxal away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0140042	lipid droplet formation	biological_process	A process that results in the assembly, arrangement of constituent parts of a lipid droplet.
GO:0140043	lipid droplet localization to prospore membrane leading edge	biological_process	Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge.
GO:0140048	manganese ion export across plasma membrane	biological_process	The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0140049	regulation of endocardial cushion to mesenchymal transition	biological_process	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition.
GO:0140050	negative regulation of endocardial cushion to mesenchymal transition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition.
GO:0140051	positive regulation of endocardial cushion to mesenchymal transition	biological_process	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition.
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus.
GO:0140053	mitochondrial gene expression	biological_process	The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0140056	organelle localization by membrane tethering	biological_process	The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.
GO:0140057	vacuole-mitochondria membrane tethering	biological_process	The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
GO:0140058	neuron projection arborization	biological_process	The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
GO:0140059	dendrite arborization	biological_process	The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.
GO:0140060	axon arborization	biological_process	The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.
GO:0140061	5-hydroxymethylcytosine dioxygenase activity	molecular_function	Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2.
GO:0140062	5-formylcytosine dioxygenase activity	molecular_function	Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2.
GO:0140064	peptide crotonyltransferase activity	molecular_function	Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide.
GO:0140065	peptide butyryltransferase activity	molecular_function	Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.
GO:0140066	peptidyl-lysine crotonylation	biological_process	The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.
GO:0140067	peptidyl-lysine butyrylation	biological_process	The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.
GO:0140068	histone crotonyltransferase activity	molecular_function	Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.
GO:0140069	histone butyryltransferase activity	molecular_function	Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.
GO:0140070	hydrogen peroxide channel activity	molecular_function	Enables the transfer of hydrogen peroxide from one side of a membrane to the other.
GO:0140074	cardiac endothelial to mesenchymal transition	biological_process	A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes.
GO:0140075	regulation of lipoprotein transport	biological_process	Any process that controls lipoprotein transport.
GO:0140076	negative regulation of lipoprotein transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.
GO:0140077	positive regulation of lipoprotein transport	biological_process	Any process that activates or increases the rate or extent of lipoprotein transport.
GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	molecular_function	Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.
GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity	molecular_function	Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH.
GO:0140081	glycosylated region protein binding	molecular_function	Binding to a glycosylated region of a protein.
GO:0140082	SUMO-ubiquitin ligase activity	molecular_function	Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
GO:0140083	ATP-dependent protein-DNA unloader activity	molecular_function	Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.
GO:0140084	sexual macrocyst formation	biological_process	The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum.
GO:0140090	membrane curvature sensor activity	molecular_function	Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins.
GO:0140091	mBAF complex	cellular_component	A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof.
GO:0140092	bBAF complex	cellular_component	A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180.
GO:0140093	esBAF complex	cellular_component	An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C.
GO:0140096	catalytic activity, acting on a protein	molecular_function	Catalytic activity that acts to modify a protein.
GO:0140097	catalytic activity, acting on DNA	molecular_function	Catalytic activity that acts to modify DNA.
GO:0140098	catalytic activity, acting on RNA	molecular_function	Catalytic activity that acts to modify RNA, driven by ATP hydrolysis.
GO:0140101	catalytic activity, acting on a tRNA	molecular_function	Catalytic activity that acts to modify a tRNA.
GO:0140102	catalytic activity, acting on a rRNA	molecular_function	Catalytic activity that acts to modify a ribosomal RNA.
GO:0140103	catalytic activity, acting on a glycoprotein	molecular_function	Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.
GO:0140104	molecular carrier activity	molecular_function	Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.
GO:0140105	interleukin-10-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-10 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0140107	high-affinity potassium ion transmembrane transporter activity	molecular_function	Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0140108	high-affinity glucose transmembrane transporter activity	molecular_function	Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
GO:0140110	transcription regulator activity	molecular_function	A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.
GO:0140111	[choline trimethylamine-lyase]-activating enzyme activity	molecular_function	Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).
GO:0140112	extracellular vesicle biogenesis	biological_process	The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
GO:0140113	extracellular microvesicle biogenesis	biological_process	The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.
GO:0140114	cellular detoxification of fluoride	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0140115	export across plasma membrane	biological_process	The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0140116	fluoride export across plasma membrane	biological_process	The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0140121	Lewy body formation	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Lewy body.
GO:0140122	regulation of Lewy body formation	biological_process	Any process that modulates the frequency, rate or extent of Lewy body formation.
GO:0140123	negative regulation of Lewy body formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation.
GO:0140124	positive regulation of Lewy body formation	biological_process	Any process that activates or increases the frequency, rate or extent of Lewy body formation.
GO:0140125	thiamine import across plasma membrane	biological_process	The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140131	positive regulation of lymphocyte chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.
GO:0140132	iron-sulfur cluster carrier activity	molecular_function	Binding to an iron-sulfur cluster and delivering it to an acceptor molecule.
GO:0140133	suppression by symbiont of host cytokine production	biological_process	Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140135	mechanosensitive monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic cation by a channel that opens in response to a mechanical stress.
GO:0140140	mitochondrial guanine nucleotide transmembrane transport	biological_process	The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0140141	mitochondrial potassium ion transmembrane transport	biological_process	The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:0140142	nucleocytoplasmic carrier activity	molecular_function	Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein.
GO:0140145	copper ion export from vacuole	biological_process	The directed movement of copper ions out of the vacuole across the vacuolar membrane.
GO:0140146	calcium ion import into vacuole	biological_process	The directed movement of calcium cations into the vacuole across the vacuolar membrane.
GO:0140147	zinc ion export from vacuole	biological_process	The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol.
GO:0140157	ammonium import across plasma membrane	biological_process	The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140159	borate export across plasma membrane	biological_process	The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0140161	monocarboxylate:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).
GO:0140164	Golgi transport complex binding	molecular_function	Binding to a Golgi transport complex, a multisubunit tethering complex of the CATCHR family.
GO:0140192	regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.
GO:0140193	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.
GO:0140194	negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.
GO:0140195	positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.
GO:0140196	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.
GO:0140199	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.
GO:0140200	adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate	biological_process	An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction.
GO:0140201	urea import across plasma membrane	biological_process	The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140202	polyamine import across plasma membrane	biological_process	The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140203	spermidine import across plasma membrane	biological_process	The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140204	pyridoxal import across plasma membrane	biological_process	The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140205	oligopeptide import across plasma membrane	biological_process	The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140206	dipeptide import across plasma membrane	biological_process	The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140207	tripeptide import across plasma membrane	biological_process	The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140208	apoptotic process in response to mitochondrial fragmentation	biological_process	Any apoptotic process that occurs as a result of mitochondrial fragmentation.
GO:0140209	zinc ion import into endoplasmic reticulum	biological_process	The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum.
GO:0140210	protein transport along microtubule to kinetochore	biological_process	Any process in which a protein is transported to the kinetochore along a microtubule.
GO:0140211	folic acid:proton symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid.
GO:0140212	regulation of long-chain fatty acid import into cell	biological_process	Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell.
GO:0140213	negative regulation of long-chain fatty acid import into cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell.
GO:0140214	positive regulation of long-chain fatty acid import into cell	biological_process	Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell.
GO:0140215	regulation of D-aspartate import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.
GO:0140216	negative regulation of D-aspartate import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.
GO:0140217	positive regulation of D-aspartate import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.
GO:0140220	pathogen-containing vacuole	cellular_component	A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides.
GO:0140221	pathogen-containing vacuole membrane	cellular_component	Host-derived membrane of a pathogen-containing vacuole.
GO:0140222	pathogen-containing vacuole lumen	cellular_component	The enclosed volume within the sealed membrane of a pathogen-containing vacuole.
GO:0140223	general transcription initiation factor activity	molecular_function	A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary.
GO:0140224	SLAC complex	cellular_component	A protein complex that regulates Arp2/3 complex-mediated actin nucleation.
GO:0140225	DNA topoisomerase III-beta-TDRD3 complex	cellular_component	A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities.
GO:0140226	RNA topoisomerase activity	molecular_function	Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA.
GO:0140227	serotonin-gated cation-selective signaling pathway	biological_process	The series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
GO:0140231	anterograde axonal transport of neurotransmitter receptor complex	biological_process	The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons.
GO:0140232	intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential.
GO:0140233	intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential	molecular_function	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential.
GO:0140235	RNA polyadenylation at postsynapse	biological_process	A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.
GO:0140236	translation at presynapse	biological_process	Translation that occurs at the presynapse.
GO:0140237	translation at presynapse, modulating chemical synaptic transmission	biological_process	Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.
GO:0140238	presynaptic endocytosis	biological_process	A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
GO:0140239	postsynaptic endocytosis	biological_process	A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
GO:0140240	perforant pathway to dendrate granule cell synapse	cellular_component	A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus.
GO:0140241	translation at synapse	biological_process	Translation that occurs at the synapse.
GO:0140242	translation at postsynapse	biological_process	Translation that occurs at the postsynapse.
GO:0140243	regulation of translation at synapse	biological_process	Any process that regulates translation occurring at the synapse.
GO:0140244	regulation of translation at presynapse	biological_process	Any process that regulates translation occurring at the presynapse.
GO:0140245	regulation of translation at postsynapse	biological_process	Any process that regulates translation occurring at the postsynapse.
GO:0140246	protein catabolic process at synapse	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein at a synapse.
GO:0140247	protein catabolic process at presynapse	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.
GO:0140249	protein catabolic process at postsynapse	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.
GO:0140250	regulation protein catabolic process at synapse	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.
GO:0140251	regulation protein catabolic process at presynapse	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.
GO:0140252	regulation protein catabolic process at postsynapse	biological_process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse.
GO:0140253	cell-cell fusion	biological_process	A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.
GO:0140255	regulation of cellular response to phosphate starvation	biological_process	Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation.
GO:0140256	negative regulation of cellular response to phosphate starvation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation.
GO:0140259	PRC1 complex binding	molecular_function	Binding to a PRC1 complex.
GO:0140260	mitochondrial proton-transporting ATP synthase complex binding	molecular_function	Binding to a mitochondrial proton-transporting ATP synthase complex.
GO:0140261	BCOR complex	cellular_component	A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10.
GO:0140262	mRNA cap binding complex binding	molecular_function	Binding to a mRNA cap binding complex.
GO:0140266	Woronin body	cellular_component	Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes.
GO:0140267	viral entry via permeabilization of host membrane	biological_process	The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm.
GO:0140268	endoplasmic reticulum-plasma membrane contact site	cellular_component	A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.
GO:0140270	gluconate import across plasma membrane	biological_process	The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140271	hexose import across plasma membrane	biological_process	The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140272	exogenous protein binding	molecular_function	Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein.
GO:0140273	repair of mitotic kinetochore microtubule attachment defect	biological_process	The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected.
GO:0140274	repair of kinetochore microtubule attachment defect	biological_process	The cell cycle process where kinetochore microtubule attachment defects are corrected.
GO:0140275	MIB complex	cellular_component	A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1.
GO:0140278	mitotic division septum assembly	biological_process	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
GO:0140279	regulation of mitotic division septum assembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0140280	negative regulation of mitotic division septum assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0140281	positive regulation of mitotic division septum assembly	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
GO:0140282	carbon-nitrogen ligase activity on lipid II	molecular_function	Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate.
GO:0140284	endoplasmic reticulum-endosome membrane contact site	cellular_component	A contact site between the endoplasmic reticulum membrane and the endosome membrane.
GO:0140285	endosome fission	biological_process	The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.
GO:0140288	GBAF complex	cellular_component	A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM.
GO:0140290	peptidyl-serine ADP-deribosylation	biological_process	The removal of ADP-ribose from ADP-ribosylserine.
GO:0140291	peptidyl-glutamate ADP-deribosylation	biological_process	The removal of ADP-ribose from ADP-ribosylglutamate.
GO:0140292	ADP-ribosylserine hydrolase activity	molecular_function	Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.
GO:0140293	ADP-ribosylglutamate hydrolase activity	molecular_function	Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose.
GO:0140294	NAD DNA ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.
GO:0140295	pathogen-derived receptor ligand activity	molecular_function	The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity.
GO:0140296	general transcription initiation factor binding	molecular_function	Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation.
GO:0140297	DNA-binding transcription factor binding	molecular_function	Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
GO:0140298	endocytic iron import into cell	biological_process	Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis.
GO:0140299	small molecule sensor activity	molecular_function	Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.
GO:0140300	serine import into mitochondrion	biological_process	The process in which serine is transported from the cytosol into the mitochondrial matrix.
GO:0140301	pollen-stigma interaction	biological_process	The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae.
GO:0140302	pollen-style interaction	biological_process	The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte.
GO:0140303	intramembrane lipid transporter activity	molecular_function	Enables the transport of a lipid from a region of a membrane to a different region on the same membrane.
GO:0140306	lipoprotein releasing activity	molecular_function	The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex.
GO:0140311	protein sequestering activity	molecular_function	Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140312	cargo adaptor activity	molecular_function	Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.
GO:0140313	molecular sequestering activity	molecular_function	Binding to a specific molecule to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140314	calcium ion sequestering activity	molecular_function	Binding to a calcium ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140315	iron ion sequestering activity	molecular_function	Binding to an iron ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140317	export across cell outer membrane	biological_process	The directed movement of a substance across the outer membrane in cells with two membranes.
GO:0140318	protein transporter activity	molecular_function	Directly binding to a specific protein and delivering it to a specific cellular location.
GO:0140319	receptor decoy activity	molecular_function	Binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor.
GO:0140320	PAMP receptor decoy activity	molecular_function	Binding and sequestering PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response.
GO:0140321	symbiont-mediated suppression of host autophagy	biological_process	Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140325	negative regulation of protein localization to medial cortex	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex.
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	molecular_function	Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.
GO:0140327	flippase activity	molecular_function	Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140328	floppase activity	molecular_function	Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140329	lysophospholipid translocation	biological_process	The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
GO:0140330	xenobiotic detoxification by transmembrane export across the cell outer membrane	biological_process	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane.
GO:0140331	aminophospholipid translocation	biological_process	The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
GO:0140332	lipopolysaccharide transfer activity	molecular_function	Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.
GO:0140333	glycerophospholipid flippase activity	molecular_function	Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140334	lipopolysaccharide localization to cell outer membrane	biological_process	A process in which a lipopolysaccharide is transported to the cell outer membrane.
GO:0140337	diacylglyceride transfer activity	molecular_function	Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location.
GO:0140338	sphingomyelin transfer activity	molecular_function	Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.
GO:0140339	phosphatidylglycerol transfer activity	molecular_function	Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location.
GO:0140340	cerebroside transfer activity	molecular_function	Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location.
GO:0140341	phosphatidylethanolamine floppase activity	molecular_function	Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140343	phosphatidylserine transfer activity	molecular_function	Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.
GO:0140344	triglyceride transfer activity	molecular_function	Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location.
GO:0140345	phosphatidylcholine flippase activity	molecular_function	Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140346	phosphatidylserine flippase activity	molecular_function	Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140347	N-retinylidene-phosphatidylethanolamine flippase activity	molecular_function	Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140348	lysophosphatidylcholine flippase activity	molecular_function	Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0140351	glycosylceramide flippase activity	molecular_function	Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.
GO:0140352	export from cell	biological_process	The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
GO:0140353	lipid export from cell	biological_process	The directed movement of a lipid from a cell, into the extracellular region.
GO:0140354	lipid import into cell	biological_process	The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
GO:0140355	cargo receptor ligand activity	molecular_function	The activity of a gene product that interacts with a cargo receptor and initiates endocytosis.
GO:0140357	heme export from vacuole to cytoplasm	biological_process	The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol.
GO:0140358	P-type transmembrane transporter activity	molecular_function	Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.
GO:0140359	ABC-type transporter activity	molecular_function	Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
GO:0140360	cyclic-GMP-AMP transmembrane transporter activity	molecular_function	Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other.
GO:0140361	cyclic-GMP-AMP transmembrane import across plasma membrane	biological_process	The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140363	TIS granule	cellular_component	A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER).
GO:0140364	GW body	cellular_component	A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs.
GO:0140365	RNP body	cellular_component	A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules.
GO:0140366	galectin lattice	cellular_component	A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids.
GO:0140367	antibacterial innate immune response	biological_process	An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0140368	decoy receptor complex	cellular_component	A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound.
GO:0140374	antiviral innate immune response	biological_process	A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0140375	immune receptor activity	molecular_function	Receiving a signal and transmitting it in a cell to initiate an immune response.
GO:0140376	innate immune receptor activity	molecular_function	Receiving a signal and transmitting it in a cell to initiate an innate immune response.
GO:0140380	psilocybin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product.
GO:0140381	4-hydroxytryptamine 4-phosphate methyltransferase activity	molecular_function	Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin.
GO:0140382	tryptamine 4-monooxygenase activity	molecular_function	Catalysis of the reaction: tryptamine + reduced acceptor + O2 <=> 4-hydroxytryptamine + acceptor + H2O.
GO:0140383	4-hydroxytryptamine kinase activity	molecular_function	Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H+.
GO:0140384	metacyclogenesis	biological_process	The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania.
GO:0140393	norsolorinic acid ketoreductase activity	molecular_function	Catalysis of the reaction: (1'S)-averantin + NADP+ <=> norsolorinic acid + NADPH.
GO:0140394	ABC-type azole transporter activity	molecular_function	Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out).
GO:0140395	averantin hydroxylase activity	molecular_function	Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O2 <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H2O. Involved in aflatoxin biosynthesis.
GO:0140396	5'-hydroxyaverantin dehydrogenase activity	molecular_function	Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD+ <=> 5'-oxoaverantin + NADH.
GO:0140397	versiconal hemiacetal acetate esterase activity	molecular_function	Catalyzes the reactions: versiconal hemiacetal acetate + H2O <=> versiconal + acetate, as well as versiconol acetate + H2O <=> versiconol + acetate.
GO:0140398	versicolorin B desaturase activity	molecular_function	Catalyzes the reaction: versicolorin B + NADPH + O2 <=> versicolorin A + NADP+ + 2 H2O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.
GO:0140399	aflatoxin B synthase activity	molecular_function	Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O2 <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H2O + methanol + CO2. Produces both aflatoxin B(1) and aflatoxin B(2).
GO:0140403	effector-mediated suppression of host innate immune response	biological_process	A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140404	effector-mediated perturbation of host innate immune response by symbiont	biological_process	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140405	spindle pole body-led chromosome movement during mitotic interphase	biological_process	A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase.
GO:0140406	L-alanine export across the plasma membrane	biological_process	The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region.
GO:0140407	L-alanine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out).
GO:0140408	regulation of mRNA alternative polyadenylation	biological_process	Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.
GO:0140409	positive regulation of mRNA alternative polyadenylation	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.
GO:0140410	monoatomic cation:bicarbonate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic cation(out) + HCO3-(out) = monoatomic cation(in) + HCO3-(in).
GO:0140412	zinc:bicarbonate symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in).
GO:0140413	zinc:bicarbonate:selenite symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out).
GO:0140414	phosphopantetheine-dependent carrier activity	molecular_function	Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.
GO:0140415	effector-mediated modulation of host defenses by symbiont	biological_process	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140416	transcription regulator inhibitor activity	molecular_function	A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification.
GO:0140417	ATP-sensitive calcium-release channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts.
GO:0140418	effector-mediated modulation of host process by symbiont	biological_process	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140420	heme import into cell	biological_process	The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
GO:0140421	endocytic heme import into cell	biological_process	The directed movement into cell of externally available heme by receptor-mediated endocytosis.
GO:0140423	effector-mediated suppression of host pattern-triggered immunity signaling	biological_process	A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants.
GO:0140425	galactose import across plasma membrane	biological_process	The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140426	pathogen-associated molecular pattern receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding of a pattern recognition receptor (PRR) to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
GO:0140429	positive regulation of mitotic sister chromatid biorientation	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed.
GO:0140430	positive regulation of chromosome passenger complex localization to kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore.
GO:0140431	DNA-(abasic site) binding	molecular_function	Binding to a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base.
GO:0140432	5'-hydroxyl dinucleotide hydrolase activity	molecular_function	Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA.
GO:0140433	regulation of protein localization to meiotic spindle pole body	biological_process	Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body.
GO:0140434	positive regulation of protein localization to meiotic spindle pole body	biological_process	Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body.
GO:0140435	negative regulation of protein localization to meiotic spindle pole body	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body.
GO:0140438	protein stearoylation	biological_process	The covalent attachment of a stearoyl group to an amino acid in a protein.
GO:0140439	protein-cysteine S-stearoyltransferase activity	molecular_function	Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein].
GO:0140440	protein-cysteine S-oleoyltransferase activity	molecular_function	Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein].
GO:0140441	protein-cysteine S-arachidonoyltransferase activity	molecular_function	Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].
GO:0140442	peroxide sensor activity	molecular_function	Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.
GO:0140443	mitochondrion-plasma membrane adaptor activity	molecular_function	The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.
GO:0140444	cytoskeleton-nuclear membrane anchor activity	molecular_function	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.
GO:0140445	chromosome, telomeric repeat region	cellular_component	A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop.
GO:0140446	fumigermin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.
GO:0140447	cytokine precursor processing	biological_process	The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.
GO:0140448	signaling receptor ligand precursor processing	biological_process	The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.
GO:0140449	centromere-nuclear envelope anchor activity	molecular_function	The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.
GO:0140450	protein targeting to Golgi apparatus	biological_process	The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).
GO:0140451	counting factor complex	cellular_component	A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum.
GO:0140453	protein aggregate center	cellular_component	Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
GO:0140454	protein aggregate center assembly	biological_process	The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
GO:0140455	cytoplasm protein quality control	biological_process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.
GO:0140456	initial meiotic spindle pole body separation	biological_process	The release of duplicated meiotic spindle pole bodies (SPBs).
GO:0140457	protein demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a protein.
GO:0140459	response to Gram-positive bacterium	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.
GO:0140460	response to Gram-negative bacterium	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium.
GO:0140462	pericentric heterochromatin organization	biological_process	The organization of chromatin into heterochromatin at the pericentric region of a chromosome.
GO:0140463	chromatin-protein adaptor activity	molecular_function	The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex.
GO:0140464	subnuclear spatial organization of silent mating-type cassette heterochromatin	biological_process	The localization of silent mating-type cassette heterochromatin at a specific location in the nucleus.
GO:0140466	iron-sulfur cluster export from the mitochondrion	biological_process	The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.
GO:0140467	integrated stress response signaling	biological_process	The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.
GO:0140468	HRI-mediated signaling	biological_process	A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.
GO:0140469	GCN2-mediated signaling	biological_process	A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.
GO:0140471	positive regulation of transepithelial migration of symbiont in host	biological_process	Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.
GO:0140472	cell cortex of non-growing cell tip	cellular_component	The region directly beneath the plasma membrane at the cell tip at which no growth takes place.
GO:0140473	telomere-nuclear envelope anchor activity	molecular_function	The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.
GO:0140474	mitochondrion-endoplasmic reticulum membrane tether activity	molecular_function	The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.
GO:0140475	spindle pole body anchor activity	molecular_function	The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.
GO:0140479	ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase	biological_process	A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.
GO:0140480	mitotic spindle pole body insertion into the nuclear envelope	biological_process	A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane.
GO:0140481	ABC-type iron-sulfur cluster transporter activity	molecular_function	Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out).
GO:0140482	iron sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron.
GO:0140483	kinetochore adaptor activity	molecular_function	The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.
GO:0140484	5-aminolevulinic acid import across plasma membrane	biological_process	The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140485	5-aminolevulinic acid transmembrane transporter activity	molecular_function	Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other.
GO:0140486	zinc ion sequestering activity	molecular_function	Binding to a zinc ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140487	metal ion sequestering activity	molecular_function	Binding to a metal ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140488	heme receptor activity	molecular_function	Binding specifically to heme to deliver it to a transport vesicle.
GO:0140489	molecular template activity	molecular_function	The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence.
GO:0140490	microtubule nucleator activity	molecular_function	The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.
GO:0140492	metal-dependent deubiquitinase activity	molecular_function	An metal-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
GO:0140493	very long-chain fatty acid beta-oxidation	biological_process	A fatty acid beta-oxidation pathway acting on a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
GO:0140494	migrasome	cellular_component	A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration.
GO:0140495	migracytosis	biological_process	A cell migration-dependent mechanism for releasing cellular contents.
GO:0140496	gamma-tubulin complex binding	molecular_function	Binding to a gamma-tubulin complex.
GO:0140497	mannan polymerase II complex	cellular_component	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p.
GO:0140498	mannan polymerase I complex	cellular_component	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p.
GO:0140499	negative regulation of mitotic spindle assembly checkpoint signaling	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.
GO:0140500	regulation of reticulophagy	biological_process	Any process that modulates the frequency, rate or extent of reticulophagy.
GO:0140501	positive regulation of reticulophagy	biological_process	Any process that increases the frequency, rate or extent of reticulophagy.
GO:0140502	effector-mediated suppression of host salicylic acid-mediated innate immune signaling	biological_process	A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signaling.
GO:0140504	microlipophagy	biological_process	Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination.
GO:0140505	regulation of microlipophagy	biological_process	Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion.
GO:0140506	endoplasmic reticulum-autophagosome adaptor activity	molecular_function	The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy.
GO:0140507	granzyme-mediated programmed cell death signaling pathway	biological_process	The series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells.
GO:0140509	epithelium-like organization	biological_process	The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.
GO:0140510	mitotic nuclear bridge	cellular_component	A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei.
GO:0140511	mitotic nuclear bridge stalk	cellular_component	Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes.
GO:0140512	mitotic nuclear bridge midzone	cellular_component	The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei.
GO:0140513	nuclear protein-containing complex	cellular_component	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.
GO:0140515	mitotic nuclear bridge organization	biological_process	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.
GO:0140516	mitotic nuclear pore complex disassembly	biological_process	The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.
GO:0140517	protein-RNA adaptor activity	molecular_function	The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way.
GO:0140522	fusogenic activity	molecular_function	The activity of joining two lipid bilayers to form a single membrane.
GO:0140523	GTPase-dependent fusogenic activity	molecular_function	A GTPase activity that mediates the joining two lipid bilayers to form a single membrane.
GO:0140525	antipodal site	cellular_component	The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication.
GO:0140526	double membrane vesicle viral factory assembly	biological_process	A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.
GO:0140527	reciprocal homologous recombination	biological_process	A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules.
GO:0140528	bilobe structure assembly	biological_process	The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).
GO:0140529	CMG complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes.
GO:0140530	MCM complex loading	biological_process	The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly.
GO:0140531	regulation of osmosensory signaling MAPK cascade	biological_process	Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade.
GO:0140532	negative regulation of osmosensory signaling MAPK cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade.
GO:0140533	suppression of host RNAi-mediated antiviral immune response	biological_process	Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140534	endoplasmic reticulum protein-containing complex	cellular_component	A protein complex that is part of an endoplasmic reticulum.
GO:0140535	intracellular protein-containing complex	cellular_component	A protein-containing complex located intracellularly.
GO:0140536	nuclear receptor corepressor activity	molecular_function	A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of transcription nuclear receptor corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
GO:0140537	transcription regulator activator activity	molecular_function	A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.
GO:0140538	negative regulation of conjugation with zygote	biological_process	A process that prevents a zygote from fusing an additional cell.
GO:0140539	regulation of melanotic encapsulation of foreign target	biological_process	Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.
GO:0140540	negative regulation melanotic encapsulation of foreign target	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.
GO:0140541	piRNA transcription	biological_process	The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
GO:0140542	regulation of piRNA transcription	biological_process	Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.
GO:0140543	positive regulation of piRNA transcription	biological_process	Any process that increases the frequency, rate or extent of the synthesis of piRNA.
GO:0140544	septin collar organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar.
GO:0140545	ATP-dependent protein disaggregase activity	molecular_function	An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.
GO:0140546	defense response to symbiont	biological_process	Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont.
GO:0140547	acquisition of seed longevity	biological_process	The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.
GO:0140548	envenomation resulting in blood agglutination in another organism	biological_process	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.
GO:0140549	spore inner membrane	cellular_component	The membrane surrounding the spore core (endospore core) that separates it from its external environment.
GO:0140550	phosphatidylinositol-4,5-bisphosphate sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate.
GO:0140552	TEAD-YAP complex	cellular_component	A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP.
GO:0140560	xylosyl alpha-1,3-xylosyltransferase activity	molecular_function	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.
GO:0140561	EGF-domain serine glucosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine.
GO:0140562	EGF-domain serine xylosyltransferase activity	molecular_function	Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.
GO:0140563	UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity	molecular_function	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.
GO:0140566	histone reader activity	molecular_function	A chromatin adaptor that recognizes specific forms of histones, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery.
GO:0140567	membrane protein dislocase activity	molecular_function	The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.
GO:0140568	extraction of mislocalized protein from membrane	biological_process	The removal of a mislocalized protein from a cellular membrane.
GO:0140569	extraction of mislocalized protein from ER membrane	biological_process	The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.
GO:0140570	extraction of mislocalized protein from mitochondrial outer membrane	biological_process	The removal of a mislocalized protein from the mitochondrial outer membrane.
GO:0140571	transmembrane ascorbate ferrireductase activity	molecular_function	Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.
GO:0140572	vacuole fission	biological_process	The division of a vacuole within a cell to form two or more separate vacuoles.
GO:0140573	histone H3-containing nucleosome	cellular_component	A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.
GO:0140575	transmembrane monodehydroascorbate reductase activity	molecular_function	Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.
GO:0140576	ascorbate homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell.
GO:0140580	mitochondrion autophagosome adaptor activity	molecular_function	The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy.
GO:0140581	P-type monovalent copper transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) = ADP + phosphate + Cu+(out).
GO:0140582	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway	biological_process	An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by extracellular cAMP binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.
GO:0140584	chromatin extrusion motor activity	molecular_function	A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis.
GO:0140585	promoter-enhancer loop anchoring activity	molecular_function	Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.
GO:0140586	promoter-terminator loop anchoring activity	molecular_function	Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.
GO:0140587	chromatin loop anchoring activity	molecular_function	Bridging together two DNA loop anchors together, maintaining a chromatin loop.
GO:0140588	chromatin looping	biological_process	A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome.
GO:0140590	effector-mediated suppression of host defense response	biological_process	A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140591	nuclear envelope budding	biological_process	The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm.
GO:0140592	histone H3R8 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to the arginine residue at position 8 of histone H3.
GO:0140593	host apoplast	cellular_component	The apoplast region surrounding a host plant cell. Plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140594	xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity	molecular_function	Stops, prevents or reduces the activity of xyloglucan-specific endo-beta-1,4-glucanase.
GO:0140595	MIM complex	cellular_component	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. MIM constitutes the major integration site for alpha-helical embedded proteins. In yeast, consists oof Mim1 and Mim2.
GO:0140596	TOM complex	cellular_component	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. TOM transports beta-barrel precursors across the outer membrane and the sorting and assembly machinery (SAM complex) inserts them into the target membrane.
GO:0140597	protein carrier chaperone	molecular_function	Binding to and carrying a protein between two different cellular components by moving along with the target protein.
GO:0140598	lipoprotein carrier activity	molecular_function	Binding to and carrying a lipoprotein between two different cellular locations by moving along with the target lipoprotein.
GO:0140599	mitotic nuclear bridge midzone membrane domain	cellular_component	A nuclear membrane part at the midzone of the mitotic nuclear bridge. The midzone forms a bulge that is enriched in nuclear pores that lack baskets.
GO:0140602	nucleolar peripheral inclusion body	cellular_component	Inclusion bodies located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress or starvation.
GO:0140604	mycofactocin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA.
GO:0140605	proton motive force-driven motor activity	molecular_function	A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella.
GO:0140608	cysteine-type endopeptidase activator activity	molecular_function	Binds to and increases the activity of a cysteine-type endopeptidase.
GO:0140609	phycocyanobilin biosynthetic process	biological_process	The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA).
GO:0140610	RNA sequestering activity	molecular_function	Binding to a specific RNA molecule to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
GO:0140612	DNA damage sensor activity	molecular_function	A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signaling response.
GO:0140613	P-type manganese transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate.
GO:0140614	1,8-dihydroxynaphthalene-melanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin.
GO:0140615	ATP-dependent citrate lyase complex	cellular_component	A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA.
GO:0140616	iodotyrosine deiodinase activity	molecular_function	Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.
GO:0140618	ferric-chelate reductase (NADH) activity	molecular_function	Catalysis of the reaction: 2 Fe3+-siderophore + NAD+ + H+ -> 2 Fe2+-siderophore + NADH.
GO:0140619	DNA strand exchange activator activity	molecular_function	Binds to and increases a DNA strand exchange activity.
GO:0140620	DNA strand exchange inhibitor activity	molecular_function	Binds to and stops, prevents or reduces a DNA strand exchange activity.
GO:0140621	type I pilus	cellular_component	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by their D-mannose-sensitive agglutinatination of erythrocytes. In E. coli, type I pili consist of a short tip fibrillum made up of the adhesin protein (FimH) and two minor subunits (FimG and FimF) that is joined to the pilus rod, a homopolymer of ~1000 FimA subunits.
GO:0140622	ER-to-endosome phospholipid transfer complex	cellular_component	Lipid transfer complex that is responsible for the non-vesicular transport of phospholipids, such as phosphatidylserine, from the endoplasmic reticulum to the endosome. It resides in the endosomal (acceptor) membrane and binds to specific lipids on the donor membrane at the ER-endosome contact site.
GO:0140623	type I pilus assembly	biological_process	The assembly from its constituent parts of a type I pilus.
GO:0140624	EGAD pathway	biological_process	The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation.
GO:0140625	opioid growth factor receptor activity	molecular_function	Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.
GO:0140626	opioid growth factor receptor signaling pathway	biological_process	The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A).
GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.
GO:0140628	outward rectifier potassium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of an outwardly rectifying potassium channel.
GO:0140629	small conductance calcium-activated potassium channel inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a small conductance calcium-activated potassium channel.
GO:0140630	all-trans-phytoene synthase activity	molecular_function	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate.
GO:0140631	aldehyde dehydrogenase (NAD+) inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).
GO:0140632	canonical inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.
GO:0140633	CARD8 inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex.
GO:0140634	CARD8 inflammasome complex	cellular_component	An inflammasome complex that consists of CARD8 and CASP1.
GO:0140635	neutrophil dispersal	biological_process	The movement of a neutrophil away from the site of wound or infection following its initial migration to the site.
GO:0140636	copper import into the mitochondrion	biological_process	The process in which copper is transported from the cytosol into the mitochondrial matrix.
GO:0140638	small ribosomal subunit processing complex	cellular_component	A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p.
GO:0140639	positive regulation of pyroptosis	biological_process	Any process that increases the frequency, rate or extent of pyroptosis.
GO:0140640	catalytic activity, acting on a nucleic acid	molecular_function	Catalytic activity that acts to modify a nucleic acid.
GO:0140641	mitotic spindle formation (spindle phase two)	biological_process	The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase.
GO:0140642	meiotic spindle formation (spindle phase two)	biological_process	The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase.
GO:0140643	hydroxymethylglutaryl-CoA reductase (NADH) activity	molecular_function	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ <=> 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.
GO:0140644	neutrophil extracellular trap	cellular_component	Extracellular microbicidal structure composed of nuclear chromatin, histones and granular antimicrobial proteins. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms.
GO:0140645	neutrophic extracellular trap formation	biological_process	The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens.
GO:0140646	negative regulation of pre-B cell receptor expression	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells.
GO:0140647	P450-containing electron transport chain	biological_process	A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.
GO:0140648	positive regulation of cell cycle switching, mitotic to meiotic cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
GO:0140649	cell-to-cell migration by invasive hypha	biological_process	The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction.
GO:0140650	radial glia-guided pyramidal neuron migration	biological_process	The radial migration of a pyramidal neuron along radial glial cells.
GO:0140651	futile creatine cycle	biological_process	The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.
GO:0140652	pyripyropene A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyripyropene A.
GO:0140654	tryprostatin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tryprostatin A.
GO:0140655	mitochondrial proliferation	biological_process	The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell.
GO:0140656	endodeoxyribonuclease activator activity	molecular_function	Binds to and increases the activity of an endodeoxyribonuclease.
GO:0140657	ATP-dependent activity	molecular_function	A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140658	ATP-dependent chromatin remodeler activity	molecular_function	An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.
GO:0140659	cytoskeletal motor regulator activity	molecular_function	Binds to and modulates the activity of a motor protein.
GO:0140660	cytoskeletal motor activator activity	molecular_function	Binds to and increases the activity of a motor protein.
GO:0140661	cytoskeletal motor inhibitor activity	molecular_function	Binds to and stops, prevents, or reduces the activity of a motor protein.
GO:0140662	ATP-dependent protein folding chaperone	molecular_function	Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
GO:0140663	ATP-dependent FeS chaperone activity	molecular_function	Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.
GO:0140664	ATP-dependent DNA damage sensor activity	molecular_function	A molecule that recognises toxic DNA structures, and initiates a signaling response, driven by ATP hydrolysis.
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	molecular_function	A histone chaperone that carries a H3-H4 histone complex, driven by ATP hydrolysis.
GO:0140666	annealing activity	molecular_function	An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.
GO:0140667	regulation of oxytocin production	biological_process	Any process that modulates the frequency, rate, or extent of production of oxytocin.
GO:0140668	positive regulation of oxytocin production	biological_process	Any process that activates or increases the frequency, rate or extent of production of oxytocin.
GO:0140669	negative regulation of oxytocin production	biological_process	Any process that stops, prevents, or reduces the rate of production of oxytocin.
GO:0140670	cohesin unloader activity	molecular_function	Facilitating a conformational change to unload a cohesin complex from sister chromatids.
GO:0140671	ADA complex	cellular_component	A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex.
GO:0140672	ATAC complex	cellular_component	A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation.
GO:0140673	transcription elongation-coupled chromatin remodeling	biological_process	A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation.
GO:0140674	ATP-dependent histone chaperone activity	molecular_function	Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome, driven by ATP hydrolysis.
GO:0140676	oscillatory cAMP signaling	biological_process	Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate.
GO:0140677	molecular function activator activity	molecular_function	A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0140678	molecular function inhibitor activity	molecular_function	A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0140679	ABC-type sodium transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) = ADP + phosphate + Na(out).
GO:0140680	histone H3K36me/H3K36me2 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0140681	histone H3K36me2/H3K36me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0140682	FAD-dependent H3K4me/H3K4me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.
GO:0140683	histone H3K9me/H3K9me2 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a di or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0140684	histone H3K9me2/H3K9me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0140685	FAD-dependent histone H3K9me/H3K9me2 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.
GO:0140690	dihydropyrimidine dehydrogenase (NAD+) complex	cellular_component	A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT.
GO:0140691	RNA folding chaperone	molecular_function	Binding to an RNA or an RNA-containing complex to assist the folding process.
GO:0140692	very long-chain fatty acid omega-hydroxylase activity	molecular_function	Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. A very long chain fatty acid is a fatty acid with an aliphatic tail of 22 or more carbons.
GO:0140693	molecular condensate scaffold activity	molecular_function	Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate.
GO:0140694	non-membrane-bounded organelle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.
GO:0140696	(S)-2-hydroxyglutarate dehydrogenase activity	molecular_function	Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol.
GO:0140698	attachment of telomeric heterochromatin to nuclear envelope	biological_process	The process in which physical connections are formed between sub-telomeric heterochromatin and the nuclear envelope facilitating bouquet formation.
GO:0140699	cyclic GMP-AMP synthase activity	molecular_function	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.
GO:0140700	3',2'-cyclic GMP-AMP synthase activity	molecular_function	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP).
GO:0140701	3',3'-cyclic GMP-AMP synthase activity	molecular_function	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP).
GO:0140702	cyclic GMP-AMP binding	molecular_function	Binding to cyclic GMP-AMP (cGAMP) nucleotide.
GO:0140703	3',3'-cyclic GMP-AMP binding	molecular_function	Binding to 3',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 3',5' linkages.
GO:0140704	3',2'-cyclic GMP-AMP binding	molecular_function	Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages.
GO:0140706	protein-containing complex localization to centriolar satellite	biological_process	A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite.
GO:0140707	chromatin-nuclear membrane anchor activity	molecular_function	Binding to chromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization, or to enable equal segregation of the nuclear membrane during mitosis.
GO:0140708	CAT tailing	biological_process	The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control sytem.
GO:0140709	Frizzled Nuclear Import pathway	biological_process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by internalization and cleavage of the frizzled receptor to yeild a C-terminal fragment that is imported into the nucleus. The frizzled C-terminal fragment is incorporated into large ribonucleoprotein particles and stimulates their egress via nuclear budding.
GO:0140710	regulation of Frizzled Nuclear Import pathway	biological_process	Any process that modulates the frequency, rate or extent of a Frizzled Nuclear Import pathway.
GO:0140711	positive regulation of Frizzled Nuclear Import pathway	biological_process	Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway.
GO:0140712	negative regulation of Frizzled Nuclear Import pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway.
GO:0140713	histone chaperone activity	molecular_function	Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome. The histone can be newly synthesized or result from nucleosome disassembly (either spontaneously, or by a histone chaperone).
GO:0140714	large ribosomal subunit pre-assembly complex	cellular_component	A protein complex that assists early maturation of nascent 60S ribosomal subunits. The complex interacts with the large ribosomal subunit rRNA via one of the components (Urb2 in S. cerevisiae) and requires a RNA helicase (Dbp6 in S. cerevisiae).
GO:0140715	serine-tRNA ligase complex	cellular_component	A heterodimeric enzyme complex that catalyzes the ligation of serine to tRNA(Ser), forming L-seryl-tRNA(Ser).
GO:0140717	entry into host through the stromata	biological_process	Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0140718	facultative heterochromatin formation	biological_process	The compaction of chromatin into a conformation that is refactory to transcription but that be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression).
GO:0140719	constitutive heterochromatin formation	biological_process	The compaction of chromatin into a conformation that is refactory to transcription.
GO:0140720	subtelomeric heterochromatin	cellular_component	Heterochromatin that is located adjacent to the telomere, and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).
GO:0140721	nuclease inhibitor activity	molecular_function	Binds to and modulates the activity of a nuclease.
GO:0140722	mycophenolic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mycophenolic acid (MPA). MPA is the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893.
GO:0140723	patulin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria.
GO:0140724	positive regulation of patulin biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of patulin.
GO:0140725	detoxification of free heme	biological_process	Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme.
GO:0140727	siRNA-dependent pericentric heterochromatin formation	biological_process	The formation of pericentric heterochromatin by a process mediated by a small interfering RNA.
GO:0140728	GC-box binding	molecular_function	Binding to a GC-box, a DNA motif with the consensus sequence GGGCGG that is located upstream of the start point of eukaryotic transcription units. The GC-box may occur in multiple copies or in either orientation relative to the transcription start site.
GO:0140729	self-resistance to endogenously produced metabolite	biological_process	A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.
GO:0140730	amphiregulin production	biological_process	The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.
GO:0140731	regulation of amphiregulin production	biological_process	Any process that modulates the frequency, rate, or extent of production of amphiregulin.
GO:0140732	positive regulation of amphiregulin production	biological_process	Any process that activates or increases the frequency, rate or extent of production of amphiregulin.
GO:0140733	tRNA ligase activator activity	molecular_function	Binds to and increases the activity of a tRNA ligase.
GO:0140734	ammonium excretion	biological_process	The elimination of ammonium ions from an excretory cell.
GO:0140735	lovastatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR).
GO:0140736	positive regulation of lovastatin biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of lovastin.
GO:0140737	encapsulin nanocompartment	cellular_component	Intracellular non-membrane bound organelle, consisting of proteinaceous polyhedral shells that encapsulate enzymes, protecting the contents from their surrounding milieu and/or the milieu from reactants in their interior. The self-assembling, 25-42 nm nanocompartment shell, unlike larger bacterial microcompartments, is made of only one protein, and has only a few proteins inside. Shells about vary from about 25-42 nm in diameter. The shell protein has an HK97-like fold and probably evolved from a viral protein. Artificial encapsulin nanocompartments can be expressed and filled with cargo proteins for biotechnological uses. They are found in many bacterial and a few archaeal phyla.
GO:0140738	NLRP6 inflammasome complex	cellular_component	An inflammasome complex that consists of NLRP6, PYCARD/ASC and caspase-1 or caspase-4/caspase-11.
GO:0140739	NLRP6 inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex.
GO:0140740	ADP-riboxanase activity	molecular_function	Catalysis of the reaction: L-arginyl-[protein] + NAD+ = ADP-riboxanated L-argininyl-[protein] + H+ + NH4(+) + nicotinamide.
GO:0140741	tRNA U4 sulfurtransferase	molecular_function	Catalyzes the reaction: ATP + [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + uracil in tRNA + 2 reduced ferredoxin [iron-sulfur] cluster <=> AMP + diphosphate + 4-thiouracil in tRNA + [ThiI sulfur-carrier protein]-L-cysteine + 2 oxidized ferredoxin [iron-sulfur] cluster.
GO:0140742	lncRNA transcription	biological_process	The transcription of lncRNAs, non-coding RNAs over 200 nucleotides in length, from a DNA template.
GO:0140743	regulation of lncRNA transcription	biological_process	Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA.
GO:0140744	negative regulation of lncRNA transcription	biological_process	Any process that decreases the frequency, rate or extent of the synthesis of a lncRNA.
GO:0140745	siRNA transcription	biological_process	The transcription of a small interfering RNA from an RNA template.
GO:0140746	siRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs).
GO:0140747	regulation of ncRNA transcription	biological_process	Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template.
GO:0140748	positive regulation of regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process.
GO:0140749	phlorizin hydrolase activity	molecular_function	Catalysis of the reaction: phlorizin + H2O = beta-D-glucose + phloretin.
GO:0140750	nucleosome array spacer activity	molecular_function	A histone octamer slider activity that spaces nucleosomes along chromosomal DNA. This activity is involved in assembling chromatin in uniform nucleosome arrays to regulate transcription by RNA polymerases I, II, and III, as well as DNA replication, recombination and repair.
GO:0140751	histone octamer slider activity	molecular_function	A chromatin remodeler activity that slides core histone octamers along chromosomal DNA.
GO:0140752	branched 1,3-beta-D-glucan synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a branched [(1->3)-beta-D-glucosyl](n+1).
GO:0140753	linear 1,3-beta-D-glucan synthase activity	molecular_function	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a linear [(1->3)-beta-D-glucosyl](n+1).
GO:0140754	reorganization of cellular membranes to establish viral sites of replication	biological_process	A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.
GO:0140755	reorganization of host cellular membranes to establish sites of replication	biological_process	A process in which a virus triggers host intracellular membranes to be reorganized, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.
GO:0140756	structural constituent of proteasome	molecular_function	The action of a molecule that contributes to the structural integrity of the proteasome.
GO:0140757	cysteine-type deNEDDylase activity	molecular_function	An thiol-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
GO:0140758	metal-dependent deNEDDylase activity	molecular_function	An metal-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
GO:0140759	histone H3K56 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 56) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 56). This reaction is the addition of a methyl group to the lysine residue at position 56 of the histone H3 protein.
GO:0140760	histone H3K56me2/H3K56me3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 56 of the histone H3 protein.
GO:0140761	calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity	molecular_function	Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.
GO:0140762	glucose dehydrogenase (FAD, quinone) activity	molecular_function	Catalysis of the reaction: a quinone + D-glucose = a quinol + D-glucono-1,5-lactone.
GO:0140763	programmed DNA elimination by elimination of internal DNA segments	biological_process	A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.
GO:0140764	small RNA binding translational repressor activity	molecular_function	A translational repressor activity that binds to a single-stranded small regulatory RNA (either a miRNA or a siRNA) to guide it to its target mRNA.
GO:0140765	NAD-dependent histone H3K56 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 56) + H2O = histone H3 L-lysine (position 56) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 56 of the histone H3 protein.
GO:0140766	siRNA-mediated post-transcriptional gene silencing	biological_process	A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants.
GO:0140767	enzyme-substrate adaptor activity	molecular_function	An adaptor that brings together an enzyme and its substrate. Adaptors recruit the substrate to its enzyme, thus contributing to substrate selection and specificity.
GO:0140768	protein ADP-ribosyltransferase-substrate adaptor activity	molecular_function	An enzyme-substrate adaptor that bings together a protein ADP-ribosyl transferase and its substrate.
GO:0140769	ACP-dependent peptidyl-lysine N6-myristoyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein].
GO:0140770	CoA-dependent peptidyl-lysine N6-myristoyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N(6)-tetradecanoyl-L-lysyl-[protein].
GO:0140771	ACP-dependent peptidyl-lysine N6-palmitoyltransferase activity	molecular_function	Catalysis of the reaction: hexadecanoyl-[ACP] + L-lysyl-[protein] = H+ + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein].
GO:0140772	CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl-[protein] + hexadecanoyl-CoA = CoA + H+ + N(6)-hexadecanoyl-L-lysyl-[protein].
GO:0140773	NAD-dependent protein demyristoylase activity	molecular_function	Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0140774	NAD-dependent protein depalmitoylase activity	molecular_function	Catalysis of the reaction: N6-octadecanoyl-L-lysyl-[protein] + NAD+ + H2O = octadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0140775	actin filament debranching activity	molecular_function	Binding to an actin filament and promoting the dissociation of an actin filament branch.
GO:0140776	protein-containing complex destabilizing activity	molecular_function	A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.
GO:0140777	protein-containing complex stabilizing activity	molecular_function	A molecular function that involves direct binding to one of the subunits of a protein-containing complex, thus preventing an interaction with a factor that would promote dissociation of the complex.
GO:0140778	microtubule stabilizing activity	molecular_function	A protein-containing complex stabilizing activity that prevents dissociation of microtubules.
GO:0140779	XCL1 production	biological_process	The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0140781	ilicicolin H biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ilicicolin H, a 4-hydroxy-2-pyridone alkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain.
GO:0140782	novofumigatonin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety.
GO:0140783	(M)-viriditoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (M)-viriditoxin, a fungal secondary metabolite with antibacterial activity.
GO:0140784	metal ion sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a metal ion.
GO:0140785	amino acid sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of an amino acid.
GO:0140786	glutamine sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of glutamine.
GO:0140787	phosphate ion uniporter activity	molecular_function	Catalysis of the active transport of a phosphate ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0140788	L-glutamate uniporter activity	molecular_function	Catalysis of the active transport of a L-glutamate across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0140789	histone phosphatase activity	molecular_function	Catalysis of the reaction: a phosphorylated histone + H2O = a protein + phosphate.
GO:0140791	histone H2AXS140 phosphatase activity	molecular_function	Catalysis of the reaction: histone H2AX serine phosphate (position 140) + H2O = histone H2AX serine (position 140) + phosphate.
GO:0140793	histone H2AXY142 phosphatase activity	molecular_function	Catalysis of the reaction: histone H2AX tyrosine phosphate (position 142) + H2O = histone H2AX tyrosine (position 142) + phosphate.
GO:0140794	histone arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone 3 L-arginyl = histone 3 L-citrullyl + NH4+, resulting in histone citrullination.
GO:0140795	histone H3R2 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.
GO:0140796	histone H3R8 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.
GO:0140797	histone H3R17 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.
GO:0140798	histone H3R26 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H3 L-arginyl (position 26)= histone H3 L-citrullyl (position 26) + NH4+, resulting in histone H3 citrullination at position 26.
GO:0140799	glycine:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + H+(in) = glycine(in) + H+(out).
GO:0140800	gamma-aminobutyric acid:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4-aminobutanoate(out) + H+(in) = 4-aminobutanoate(in) + H+(out).
GO:0140801	histone H2AXY142 kinase activity	molecular_function	Catalysis of the reaction: histone H2AX-tyrosine (position 142) + ATP = (histone H2AX-phosphotyrosine (position 142) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 142 of histone variant H2AX.
GO:0140802	NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide.
GO:0140803	NAD+- protein-cysteine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein].
GO:0140804	NAD+- protein-lysine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl-[protein] + NAD+ = H+ + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide.
GO:0140805	NAD+-protein-serine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-seryl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein].
GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide.
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide.
GO:0140808	NAD+-protein-tyrosine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein].
GO:0140809	histone H4R3 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H4 L-arginyl (position 3)= histone H4 L-citrullyl (position 3) + NH4+, resulting in histone H4 citrullination at position 3.
GO:0140810	histone H1R54 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H1 L-arginyl (position 54)= histone H1 L-citrullyl (position 54) + NH4+, resulting in histone H1 citrullination at position 54.
GO:0140811	histone H2AR3 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone 2A L-arginyl (position 3)= histone 2A L-citrullyl (position 3) + NH4+, resulting in histone H2A citrullination at position 3.
GO:0140812	orotate:monoatomic anion antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: orotate(out) + anion (in) = orotate (in) + anion (out).
GO:0140813	urate:monoatomic anion antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urate(out) + anion (in) = urate (in) + anion (out).
GO:0140814	glycine betaine:sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + Na+(out) + Cl-(out)= glycine betaine(in) + Na+(in) + Cl-(in).
GO:0140815	NAD+-protein-histidine ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: L-histidyl-[protein] + NAD+ = H+ + Nt-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide.
GO:0140816	NAD+-histone H2BS6 serine ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of ADP-ribose groups to the serine-6 or an equivalent residue of the N-terminal tail of histone H2B.
GO:0140817	NAD+-histone H3S10 serine ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3.
GO:0140818	mRNA 5'-phosphatase activity	molecular_function	A 5'-end triphospho-[mRNA] + H2O = a 5'-end diphospho-[mRNA] + H+ + phosphate.
GO:0140819	UDP-beta-L-arabinofuranose transporter activity	molecular_function	Enables the transfer of UDP-beta-L-arabinofuranose from one side of a membrane to the other.
GO:0140820	cytosol to Golgi apparatus transport	biological_process	The directed movement of substances from the cytosol into the Golgi apparatus of a cell.
GO:0140821	UDP-beta-L-arabinofuranose import into Golgi lumen	biological_process	The directed movement of UDP-beta-L-arabinofuranose from the cytosol to the Golgi apparatus of a cell.
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of ADP-ribose groups to the glutamate-35 residue of the N-terminal tail of histone H2B (or an equivalent residue).
GO:0140823	histone H2BS36 kinase activity	molecular_function	Catalysis of the reaction: histone H2B-serine (position 36) + ATP = histone H2B-phosphoserine (position 36) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 36 of histone H2B.
GO:0140824	thioredoxin-dependent peroxiredoxin activity	molecular_function	Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.
GO:0140825	lactoperoxidase activity	molecular_function	Catalysis of the reaction: 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O.
GO:0140826	zinc:proton antiporter activity	molecular_function	Enables the transfer of zinc from one side of a membrane to the other according to the reaction: H+(out) + Zn2+(in) = H+(in) + Zn2+(out).
GO:0140827	zinc chaperone activity	molecular_function	Binding to and delivering zinc ions to a target protein.
GO:0140828	metal cation:monoatomic cation antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(in) = solute(in) + Na+(out).
GO:0140829	bicarbonate:monoatomic anion antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(in) + HCO3-(out) = solute(out) + HCO3-(in).
GO:0140830	L-glutamine, sodium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-glutamine(out) + Na+(out) = H+(out) + L-glutamine(in) + Na+(in).
GO:0140831	L-asparagine, sodium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-asparagine(out) + Na+(out) = H+(out) + L-asparagine(in) + Na+(in).
GO:0140832	L-histidine, sodium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + L-histidine(out) + Na+(out) = H+(out) + L-histidine(in) + Na+(in).
GO:0140833	RNA polymerase II CTD heptapeptide repeat Y1 kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphotyrosine (position 1).
GO:0140834	RNA polymerase II CTD heptapeptide repeat S2 kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 2).
GO:0140835	RNA polymerase II CTD heptapeptide repeat T4 kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphothreonine (position 4).
GO:0140836	RNA polymerase II CTD heptapeptide repeat S5 kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 5).
GO:0140837	RNA polymerase II CTD heptapeptide repeat S7 kinase activity	molecular_function	Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + RNA polymerase II large subunit phosphoserine (position 7).
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) = RNA polymerase II large subunit trans-proline (omega=0).
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 3) = RNA polymerase II large subunit trans-proline (omega=0) (position 3).
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) cis-proline (omega=180) (position 6) = RNA polymerase II large subunit trans-proline (omega=0) (position 6).
GO:0140841	RNA polymerase II C-terminal domain O-GlcNAc transferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine.
GO:0140842	RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 5).
GO:0140843	RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity	molecular_function	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 7).
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of ADP-ribose groups to the glutamate-2 residue of the N-terminal tail of histone H2B (or an equivalent residue).
GO:0140845	regulation of promoter clearance from RNA polymerase II promoter	biological_process	A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
GO:0140846	positive regulation of promoter clearance from RNA polymerase II promoter	biological_process	A process that activates or increases the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
GO:0140847	negative regulation of promoter clearance from RNA polymerase II promoter	biological_process	A process that stops, prevents or reduces the transition from the initiation to the elongation phases of transcription by RNA polymerase II.
GO:0140848	amino acid:monoatomic cation antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + monoatomic cation(in) = solute(in) + monoatomic cation(out). Monoatomic cations include H+, Mg2+, Ca2+, etc.
GO:0140849	ATP-dependent H2AZ histone chaperone activity	molecular_function	A histone chaperone that mediates the exchange of histone H2A-H2B dimer and histone H2AZ-H2B dimers in a nucleosome, driven by ATP hydrolysis. Some chaperones insert H2AZ-H2B dimers and remove H2A-H2B, while others do the opposite.
GO:0140850	histone H2B C-terminal K residue ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to a histone 2B at the conserved C-terminal lysine (K) residue. The last K residue is at position 119 in fission yeast, 123 in budding yeast, and 120 in mammals.
GO:0140851	histone H3K14 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 3 at the lysine-14 residue.
GO:0140852	histone ubiquitin ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a histone substrate.
GO:0140853	cholesterol-protein transferase activity	molecular_function	Catalysis of the transfer of a cholesterol to an acceptor protein.
GO:0140854	interleukin-19-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0140855	histone H3S57 kinase activity	molecular_function	Catalysis of the reaction: histone H3-serine (position 57) + ATP = histone H3-phosphoserine (position 57) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 57 of histone H3.
GO:0140856	histone H2AK13 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-13 residue.
GO:0140857	histone H3T45 kinase activity	molecular_function	Catalysis of the reaction: histone H3-threonine (position 45) + ATP = histone H3-phosphothreonine (position 45) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 45 of histone H3.
GO:0140858	histone H2AK15 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-15 residue.
GO:0140859	pterocarpan synthase activity	molecular_function	Catalysis of the reaction: H2O + medicarpin = 4'-methoxyisoflavan-2',4,7-triol.
GO:0140860	(3R)-2'-hydroxyisoflavanone reductase activity	molecular_function	Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH.
GO:0140861	DNA repair-dependent chromatin remodeling	biological_process	A chromatin remodeling process that allows DNA repair enzyme to access genomic DNA and repair DNA lesions.
GO:0140862	histone H2AK119 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.
GO:0140863	histone H2AK127 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-127 residue.
GO:0140864	histone H2AK129 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-129 residue.
GO:0140865	interleukin-22-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-22 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0140866	interleukin-20-mediated signaling pathway	biological_process	The series of molecular signals initiated by interleukin-20 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	molecular_function	Catalysis of the transfer of ADP-ribose groups to the glutamate-18 residue of histone H2B (or an equivalent residue).
GO:0140868	4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)	molecular_function	Catalysis of the reaction: 3 H+ + 15-cis-4,4'-diapophytoene + 4 FAD = 4,4'-diapolycopene + 3 FADH2. This reaction consists of three successive dehydrogenations that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
GO:0140869	miRNA inhibitor activity via base-pairing	molecular_function	Stops, prevents or reduces the activity of miRNA-mediated gene silencing activity by base-pairing with a target miRNA. An example of this activity is mediated by long non-coding RNAs (lncRNAs).
GO:0140870	RNA polymerase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of RNA polymerase.
GO:0140871	repressor of RNA polymerase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of an RNA polymerase inhibitor.
GO:0140872	viridicatumtoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system.
GO:0140873	paxilline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of paxilline, a mycotoxin that acts as an inhibitor of mammalian maxi-K channels.
GO:0140874	paraherquonin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture.
GO:0140875	PR-toxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin.
GO:0140876	andrastin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of andrastin A, a meroterpenoid that exhibits inhibitory activity against ras farnesyltransferase, suggesting that it could have promising antitumor activity.
GO:0140877	mevastatin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mevastatin , also known as compactin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase.
GO:0140878	griseofulvin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections.
GO:0140879	conidiogenone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation.
GO:0140880	terrein biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of terrein, a fungal metabolite with ecological, antimicrobial, antiproliferative, and antioxidative activities.
GO:0140881	positive regulation terrein biosynthetic process	biological_process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of the fungal metabolite terrein.
GO:0140882	zinc export across plasma membrane	biological_process	The directed movement of zinc ions from a cell, into the extracellular region.
GO:0140883	induction by virus of host reticulophagy	biological_process	Any process in which a virus activates or increases the frequency, rate or extent of reticulophagy in the host.
GO:0140884	suppression by virus of host type II interferon-mediated signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type II interferon-mediated signaling in the host organism. Type II interferon is also known as interferon-gamma.
GO:0140885	suppression by virus of host type III interferon-mediated signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type III interferon-mediated signaling in the host organism. Type III interferon is also known as interferon-lambda.
GO:0140886	suppression by virus of host interferon-mediated signaling pathway	biological_process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.
GO:0140887	positive regulation of nucleosome disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of the controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
GO:0140888	interferon-mediated signaling pathway	biological_process	The series of molecular signals initiated by type II interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type II interferon is also known as interferon-gamma.
GO:0140889	DNA replication-dependent chromatin disassembly	biological_process	The disruption of nucleosomes during DNA replication to allow the replication machinery to access the DNA.
GO:0140890	H1 histone chaperone activity	molecular_function	A histone chaperone that carries a H1 histone.
GO:0140891	tRNA-derived regulatory ncRNA processing	biological_process	A process leading to the generation of a functional small regulatory non-coding RNA derived from a tRNA.
GO:0140892	sodium,bicarbonate:chloride antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction chloride(in) + 2 hydrogencarbonate(out) + Na+(out) = chloride(out) + 2 hydrogencarbonate(in) + Na+(in).
GO:0140893	neutral amino acid, sodium:proton antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(in) + amino acid(out) + Na+(out) = H+(out) + amino acid(in) + Na+(in).
GO:0140894	endolysosomal toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to an endolysosomal pattern recognition receptor (PRR) of the toll-like family. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.
GO:0140895	cell surface toll-like receptor signaling pathway	biological_process	The series of molecular signals initiated by a ligand binding to a cell surface pattern recognition receptor (PRR) of the toll-like family.
GO:0140896	cGAS/STING signaling pathway	biological_process	The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING.
GO:0140897	mechanoreceptor activity	molecular_function	Combining with a mechanical force and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
GO:0140898	CENP-A eviction from euchromatin	biological_process	A chromatin remodeling process in which CENP-A is removed from euchromatin regions to prevent neocentromere formation.
GO:0140899	plastid gene expression	biological_process	The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0140900	chloride:bicarbonate antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + HCO3-(out) = chloride(out) + HCO3-(in).
GO:0140901	L-asparagine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).
GO:0140902	L-glutamine:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + Na+(out) = L-glutamine(in) + Na+(in).
GO:0140903	histone H3R26 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 26) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 26). This reaction is the addition of a methyl group to the arginine residue at position 26 of histone H3.
GO:0140904	cytoophidium organization	biological_process	A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes.
GO:0140905	haloperoxidase activity	molecular_function	Catalysis of the reaction: R-CH + a halogen + H2O2 = R-C-halogen + H2O.
GO:0140906	halogenase activity	molecular_function	Catalysis of the reaction: R-CH + a halogen + oxygen donor = R-C-halogen +H2O.
GO:0140907	flavin-dependent halogenase activity	molecular_function	Catalysis of the reaction: R-CH + a halogen + FADH2 + O2 = R-C-halogen + FAD + H2O.
GO:0140908	histone H3K122 acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 122) = CoA + histone H3 N6-acetyl-L-lysine (position 122).
GO:0140909	kinetoplast DNA replication	biological_process	The process of doubling of the number of maxicircles and minicircles and distribution of the progeny into two daughter networks, which are identical to the parent kinetoplast DNA network.
GO:0140910	iRhom2/ADAM17 sheddase complex	cellular_component	A complex consisting of ADAM17 in complex with regulatory iRhoms and FERM domain containing proteins.
GO:0140911	pore-forming activity	molecular_function	An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death.
GO:0140912	membrane destabilizing activity	molecular_function	Binding to a membrane and increasing its permeability. This may lead to cell membrane lysis and cell content release.
GO:0140913	viral release via disruption of host peptidoglycan cell wall	biological_process	The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
GO:0140914	zinc ion import into secretory vesicle	biological_process	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a secretory vesicle.
GO:0140915	zinc ion import into zymogen granule	biological_process	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a zymogen granule.
GO:0140916	zinc ion import into lysosome	biological_process	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a lysosome.
GO:0140917	zinc ion import into mitochondrion	biological_process	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into a mitochondrion.
GO:0140918	centrosomal core	cellular_component	The core region of the centrosome, a layered structure containing proteins, surrounded by the centrosomal corona. The core duplicates once per cell cycle at the G2/M transition when two outer layers form the mitotic spindle poles.
GO:0140919	thermomorphogenesis	biological_process	The suite of morphological and architectural changes in an organism induced by high ambient temperatures, below the heat-stress range.
GO:0140920	regulation of thermomorphogenesis	biological_process	Any process that modulates the frequency, rate or extent of thermomorphogenesis.
GO:0140921	negative regulation of thermomorphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thermomorphogenesis.
GO:0140922	positive regulation of thermomorphogenesis	biological_process	Any process that increases the rate, frequency or extent of thermomorphogenesis.
GO:0140923	magnetosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB).
GO:0140924	L-kynurenine transmembrane transport	biological_process	The directed movement of L-kynurenine across a membrane.
GO:0140925	L-phenylalanine import across plasma membrane	biological_process	The directed movement of L-phenylalanine from outside of a cell, across the plasma membrane and into the cytosol.
GO:0140926	L-kynurenine transmembrane transporter activity	molecular_function	Enables the transfer of L-kynurenine from one side of a membrane to the other.
GO:0140927	cyclic-di-GMP transmembrane transporter activity	molecular_function	Enables the transfer of cyclic-di-GMP from one side of a membrane to the other.
GO:0140928	inhibition of non-skeletal tissue mineralization	biological_process	A homeostatic process involved in the maintenance of non-mineral tissue, by preventing mineralization of non-skeletal tissue.
GO:0140929	mannose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-mannose(out) + Na+(out) = D-mannose(in) + Na+(in).
GO:0140930	fructose:sodium symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-fructose(out) + Na+(out) = D-fructose(in) + Na+(in).
GO:0140931	neutral L-amino acid:sodium:chloride symporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) + Cl-(out) = neutral L-amino acid(in) + Na+(in)+ Cl-(in).
GO:0140932	5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity	molecular_function	Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.
GO:0140933	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	molecular_function	Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.
GO:0140934	histone deubiquitinase activity	molecular_function	A deubiquitinase that cleaves ubiquitin from a histone protein to which it is conjugated.
GO:0140935	histone H2B conserved C-terminal lysine deubiquitinase activity	molecular_function	A histone deubiquitinase that cleaves ubiquitin from the conserved C-terminal lysine residue of a histone H2B protein to which it is conjugated. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, and K120 in mammals.
GO:0140936	histone H2B deubiquitinase activity	molecular_function	A histone deubiquitinase that cleaves ubiquitin from a histone H2B protein to which it is conjugated.
GO:0140937	histone H4K12 deacetylase activity	molecular_function	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 12) + H2O = histone H4 L-lysine (position 12) + acetate. This reaction represents the removal of an acetyl group from lysine at position 12 of the histone H4 protein.
GO:0140938	histone H3 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a histone H3 = S-adenosyl-L-homocysteine + a methylated histone H3. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0140939	histone H4 methyltransferase activity	molecular_function	Catalysis of the reaction: Catalysis of the reaction: S-adenosyl-L-methionine + a histone H4 = S-adenosyl-L-homocysteine + a methylated histone H4. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0140940	histone H2A methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + a histone H2 = S-adenosyl-L-homocysteine + a methylated histone H2A. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0140941	histone H4K20me methyltransferase activity	molecular_function	Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.
GO:0140942	histone H3K9 dimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl9-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl9-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me2.
GO:0140943	histone H4K20 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H+ + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to the lysine residue at position 20 of the histone H4 protein, producing histone H4K20me3.
GO:0140944	histone H4K20 monomethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl20-[histone H4] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl20-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 20 of histone H4, producing histone H4K20me.
GO:0140945	histone H3K4 monomethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl4-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl4-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me.
GO:0140946	histone H3K4 dimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl4-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl4-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me2.
GO:0140947	histone H3K9me2 methyltransferase activity	molecular_function	Catalysis of the reaction: N6,N6-dimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the dimethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.
GO:0140948	histone H3K9 monomethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me.
GO:0140949	histone H3K9 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl9-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.
GO:0140950	histone H2A deubiquitinase activity	molecular_function	A histone deubiquitinase that cleaves ubiquitin from a histone H2A protein to which it is conjugated.
GO:0140951	histone H3K27 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl27-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl27-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me3.
GO:0140952	histone H3K27 dimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.
GO:0140953	histone H3K27 monomethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.
GO:0140954	histone H3K36 dimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl36-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me2.
GO:0140955	histone H3K36 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl36-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl36-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me3.
GO:0140956	histone H3K79 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl79-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl79-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of up to three methyl group to the lysine residue at position 79 of the histone H3 protein, producing H3K79me3.
GO:0140958	target-directed miRNA degradation	biological_process	The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases.
GO:0140961	cellular detoxification of metal ion	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion.
GO:0140962	multicellular organismal-level chemical homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
GO:0140964	intracellular auxin homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of auxin within a cell.
GO:0140965	secondary piRNA processing	biological_process	A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4.
GO:0140966	piRNA-mediated heterochromatin formation	biological_process	The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering piRNA.
GO:0140967	manganese import into cell	biological_process	The directed movement of mangnanese ions from outside of a cell into a cell.
GO:0140968	polyspecific organic cation:proton antiporter activity	molecular_function	Enables the transfer of various organic cations in exchange for a proton, according to the reaction: H+(out) + organic cation(in) = H+(in) + organic cation(out). The transported substrates are usually toxic molecules, drugs and xenobiotics.
GO:0140969	determination of lung left/right asymmetry	biological_process	Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism.
GO:0140970	AIM2 inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the AIM2 inflammasome complex.
GO:0140971	regulation of AIM2 inflammasome complex assembly	biological_process	Any process that modulates the frequency, rate or extent of AIM2 inflammasome complex assembly.
GO:0140972	negative regulation of AIM2 inflammasome complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of AIM2 inflammasome complex assembly.
GO:0140973	positive regulation of AIM2 inflammasome complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly.
GO:0140974	cellular detoxification of sulfide	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0140975	disruption of cellular anatomical structure in another organism	biological_process	The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. In some cases this can cause malfunctioning of the cells and death of the target organism.
GO:0140976	defense response against perturbation of plasma membrane integrity	biological_process	The cellular processes and signaling pathways by which a cell responds to disruption of the integrity of its plasma membrane by another organism. Some toxins produced by other organisms can form pores in membranes, or affect the membrane permeability.
GO:0140977	cellular detoxification of acetone	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of acetone. These may include chemical modification, for example to methylglyoxal.
GO:0140978	mitochondrial large ribosomal subunit binding	molecular_function	Binding to a mitochondrial large ribosomal subunit.
GO:0140979	intracellular nucleotide homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell.
GO:0140980	intracellular nucleoside homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell.
GO:0140981	medium-chain fatty acid omega-hydroxylase activity	molecular_function	Catalysis of the reaction: an omega-methyl-medium-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A medium-chain fatty acid is a fatty acid with an aliphatic tail of 6 to 12 carbons.
GO:0140982	detoxification of aluminum ion	biological_process	Any process that reduce or remove the toxicity of aluminum ions. These can include transport of the aluminum away from sensitive areas,  sequesteration, or chemical modification to an inert form.
GO:0140983	calcium:manganese antiporter activity	molecular_function	Catalysis of the reaction: Ca2+(in) + Mn2+(out) = Ca2+(out) + Mn2+(in).
GO:0140984	histone H4K12 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.
GO:0140985	G protein-coupled chemorepellent receptor activity	molecular_function	Combining with a chemorepellent and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0140986	G protein-coupled chemorepellent receptor signaling pathway	biological_process	A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. cytoskeleton reorganization.
GO:0140987	ATP:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of ATP from one side of a membrane to the other according to the reaction: ATP(out) + inorganic phosphate(in) = ATP(in) + inorganic phosphate(out).
GO:0140988	ADP:inorganic phosphate antiporter activity	molecular_function	Enables the transfer of ADP from one side of a membrane to the other according to the reaction: ADP(out) + inorganic phosphate(in) = ADP(in) + inorganic phosphate(out).
GO:0140989	7-deoxyloganate 7-hydroxylase activity	molecular_function	Catalysis of the reaction:  7-deoxyloganate + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O +  loganate + oxidized [NADPH-hemoprotein reductase].
GO:0140990	primary piRNA processing	biological_process	The process involved in converting precursor piRNAs into non-overlapping, contiguous primary piRNAs (approximately 24-30-nt piRNAs with a preference for a 5' uridine (U) via the endonucleolytic activity of cytosolic PIWI. This may include pre-piRNA maturation of 3' ends by trimming and 2'-O-methylation.
GO:0140991	piRNA-mediated gene silencing by mRNA destabilization	biological_process	A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping.
GO:0140993	histone modifying activity	molecular_function	A catalytic activity that acts on a histone protein. Reversible histone modifications contribute to regulation of gene expression.
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	molecular_function	A catalytic activity that acts on the RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS). Reversible modifications cof the RNA polymerase II CTD repeats contribute to regulation of RNA polymerase activity.
GO:0140995	histone H2A kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone H2A.
GO:0140996	histone H3 kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone H3.
GO:0140997	histone H4 kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone H4.
GO:0140998	histone H2B kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone H2B.
GO:0140999	histone H3K4 trimethyltransferase activity	molecular_function	Catalysis of the reaction: L-lysyl4-[histone H3] + 3 S-adenosyl-L-methionine = 2 H+ + N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me3.
GO:0141000	histone H4K91 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of a ubiquitin molecule to histone 4 at the lysine-91 residue.
GO:0141002	histone H4K16 propionyltransferase activity	molecular_function	Catalysis of the reaction: histone H4 L-lysine (position 16) + propionyl-CoA = CoA + H+ + histone H3 N6-propionyl-L-lysyl (position 16).
GO:0141003	histone H2AX kinase activity	molecular_function	Catalysis of the transfer of a phosphate group to a histone variant H2AX.
GO:0141005	retrotransposon silencing by heterochromatin formation	biological_process	A retrotransposon silencing mechanism involving heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.
GO:0141006	piRNA-mediated retrotransposon silencing by heterochromatin formation	biological_process	A retrotransposon silencing mechanism in which a piRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.
GO:0141007	siRNA-mediated retrotransposon silencing by heterochromatin formation	biological_process	A retrotransposon silencing mechanism in which a siRNA triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.
GO:0141008	retrotransposon silencing by mRNA destabilization	biological_process	A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation.
GO:0141009	piRNA-mediated retrotransposon silencing by mRNA destabilization	biological_process	A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a piRNA.
GO:0141010	retrotransposon silencing by RNA-directed DNA methylation	biological_process	A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.
GO:0141011	siRNA-mediated retrotransposon silencing by mRNA destabilization	biological_process	A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA.
GO:0141013	purine nucleotide import into lysosome	biological_process	The directed import of purine nucleotide from the cytosol, across the lysosomal membrane, into the lysosome.
GO:0141014	ribosome hibernation	biological_process	A cellular process that results in the silencing of ribosomes in quiescent cells. Quiescence takes place when cells encounter unfavorable conditions and cease to grow in bacteria and yeast. It also takes place in some specialized cells in higher eukaryotes, such as eggs. Ribosomes in a hibernation state are kept silent via association with proteins with inhibitory and protective functions.
GO:0141016	G/T mismatch-specific thymine-DNA glycosylase activity	molecular_function	Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site.
GO:0141017	effector-mediated induction of cell cycle reactivation in host	biological_process	A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation.
GO:0141018	adhesion of symbiont to host via host extracellular matrix	biological_process	The attachment of a symbiont to its host by binding to a component of the host extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141023	disruption by symbiont of host cell-cell adhesion	biological_process	The process by which a symbiont disupts cell-cell adhesion in its host.
GO:0141024	adhesion of symbiont to host cell surface via host membrane carbohydrate	biological_process	The attachment of a symbiont to its host by binding to a carbohydrate on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141025	adhesion of symbiont to host cell surface via host glycoprotein	biological_process	The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141026	adhesion of symbiont to host cell surface via host membrane cholesterol	biological_process	The attachment of a symbiont to its host by binding to cholesterol on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141027	perturbation by symbiont of host actin cytoskeleton	biological_process	The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141028	perturbation by symbiont of host microtubule cytoskeleton	biological_process	The process in which an organism effects a change that impairs the structure or function of the host microtubule cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141029	disruption by symbiont of host focal adhesion	biological_process	The process by which a symbiont disupts host focal adhesion in its host.
GO:0141030	perturbation by symbiont of host actin cytoskeleton via filamentous actin depolymerization	biological_process	The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141031	perturbation by symbiont of host actin cytoskeleton via actin crosslinking	biological_process	The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by actin crosslinking the host actin filaments. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141032	perturbation by symbiont of host actin cytoskeleton via actin filament reorganization	biological_process	The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141033	perturbation by symbiont of host actin cytoskeleton via actin polymerization	biological_process	The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by polymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141034	perturbation by symbiont of host actin cytoskeleton via inhibition of actin polymerization	biological_process	The process in which an organism effects a change that disrupts the host actin cytoskeleton by inhibiting host actin from polymerizing. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141035	CTP-dependent diacylglycerol kinase activity	molecular_function	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + CTP = a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H+.
GO:0141038	phosphatidylinositol 3-kinase activator activity	molecular_function	Binds to and increases the activity of a phosphatidylinositol 3-kinase (PI3K).
GO:0141039	phosphatidylinositol 3-kinase inhibitor activity	molecular_function	Binds to and decreases the activity of a phosphatidylinositol 3-kinase (PI3K).
GO:0141040	very-long-chain 3-oxoacyl-CoA reductase activity	molecular_function	Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH.
GO:0141041	disruption of extracellular matrix of another organism	biological_process	The chemical reactions and pathways performed by an organism resulting in the breakdown of the extracellular matrix of another organism.
GO:0141042	symbiont-mediated cAMP intoxication of host cell	biological_process	The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141043	evasion of host innate immune recognition	biological_process	A process by which a symbiont avoids recognition by host's innate immune response by altering a conserved molecule recognized by the host's cell surface and intracellular innate immune receptors, including Toll-like receptors, and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141044	epigenetic programming in the endosperm	biological_process	The global programming of epigenetic modifications following binucleate central cell fertilization. This involves DNA methylation at the silent allele. In the endosperm, maternal genomes are hypomethylated compared with the paternal genome.
GO:0141046	Atg8-family conjugating enzyme activity	molecular_function	Isoenergetic transfer of an Atg8 family modifer from one protein to a phosphatidylethanolamine or  phosphatidylserine on a membrane, via the reaction X-Atg8 + Y = Y-Atg8 + X.
GO:0141047	molecular tag activity	molecular_function	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another molecule (for example a protein or a lipid) where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.
GO:0141048	membrane tag activity	molecular_function	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to a lipid, where it acts as a marker for a membrane, recognized by the cellular apparatus to target the tagged protein for some cellular process such as autophagy.
GO:0141049	protein-glutathione oxidoreductase (glutathione) activity	molecular_function	Catalysis of the reaction: glutathionylated protein (PSSG) + glutathione (GSH) = protein-thiol (PSH) + glutathione disulfide (GSSG). The reaction may proceed via a 'monothiol' or 'dithiol' mechanism.
GO:0141050	histone H3K deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine + H2O = histone H3 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H3.
GO:0141051	histone H4K deacetylase activity	molecular_function	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine + H2O = histone H4 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H4.
GO:0141052	histone H3 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a modified lysine residue of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0141053	histone H2A ubiquitin ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a histone H2A substrate.
GO:0141054	histone H2B ubiquitin ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a histone H2B substrate.
GO:0141055	histone H3 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a histone H3 substrate.
GO:0141056	histone H4 ubiquitin ligase activity	molecular_function	Catalysis of the transfer of ubiquitin to a histone H4 substrate.
GO:0141057	histone H3 arginine deiminase activity	molecular_function	Catalysis of the reaction: H2O + histone H3 L-arginyl = histone H3 L-citrullyl + NH4+, resulting in histone H3 citrullination.
GO:0141058	histone H4 demethylase activity	molecular_function	Catalysis of the removal of a methyl group from a modified lysine residue of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0141059	disruption of host antimicrobial peptide activity	biological_process	Any process in which a symbiont interferes with a host antimicrobial peptide, for example by cleavage or degredation.
GO:0141060	disruption of anatomical structure in another organism	biological_process	The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure.
GO:0141061	disruption of cell in another organism	biological_process	The disruption of a cell of another organism, leading to damage or temporary subversion of that cell.
GO:0141062	disruption of tissue in another organism	biological_process	The disruption of the a tissue of another organism, leading to damage or temporary subversion of that tissue.
GO:0141063	epigenetic programming in the central cell	biological_process	The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation.
GO:0141064	zygotic genome activation	biological_process	A process that contributes to the onset of de novo transcription from the zygotic genome as part of the maternal-to-zygote transition in gene expression. The zygote overcomes the silencing that has been established. The cause of this silencing could be due to several factors: chromatin modifications leading to repression, or lack of adequate transcription machinery.
GO:0141065	maternal mRNA clearance	biological_process	The chemical reactions and pathways resulting in the clearance of maternal mRNA transcripts from the zygote as part of the maternal-to-zygote transition in gene expression.
GO:0141066	disruption of host extracellular matrix	biological_process	The chemical reactions and pathways performed by an symbiont resulting in the breakdown of the extracellular matrix of its host.
GO:0141067	intracellular nitrogen homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell.
GO:0141068	autosome genomic imprinting	biological_process	The establishment of epigenetic modifications (imprints) in autosomal (non-sexual) chromosomes during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.
GO:0141069	receptor ligand inhibitor activity	molecular_function	Binds to and decreases the activity of the ligand of a signaling receptor.
GO:0141070	symbiont-mediated suppression of host MAPK signal transduction pathway	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a MAPK signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141071	symbiont-mediated activation of host MAPK signal transduction pathway	biological_process	A process in which a symbiont subverts a MAPK signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141072	symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway	biological_process	A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141073	disruption by symbiont of host opsonization	biological_process	Any process in which a symbiont interferes with, inhibits or stops opsonization by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141074	symbiont-mediated suppression of host cGAS-STING signal transduction	biological_process	A process in which a virus interferes with, inhibits or disrupt a cGAS/STING signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141075	symbiont-mediated suppression of host JAK-STAT cascade	biological_process	A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141076	symbiont-mediated suppression of host TRAF-mediated signal transduction	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a TRAF-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141077	suppression of host interferon-mediated signaling pathway	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism.
GO:0141078	symbiont-mediated suppression of host RIG-I signaling pathway	biological_process	A process in which a symbiont interferes with, inhibits or disrupts a RIG-I signaling pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141079	symbiont-mediated activation of host inflammasome-mediated signal transduction	biological_process	A process in which a symbiont subverts an inflammasome-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141080	symbiont-mediated activation of host interferon signaling pathway	biological_process	A process in which a symbiont subverts an interferon-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation.
GO:0141081	symbiont-mediated suppression of host inflammasome-mediated signal transduction	biological_process	A process in which a symbiont interferes with, inhibits or stops an  inflammasome-mediated signal transduction pathway in the host organism by  interfering with its normal execution. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141082	symbiont-mediated detoxification of host-generated reactive oxygen species	biological_process	A process in which a symbiont interferes with, inhibits or disrupts the host reactive oxygen species (ROS)-mediated innate immune response by directly degrading host ROS. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141083	symbiont-mediated suppression of host reactive oxygen species generation	biological_process	A process in which a symbiont interferes with, inhibits or disrupts the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141084	inflammasome-mediated signaling pathway	biological_process	An intracellular signal transduction pathway that starts with a ligand binding to a pattern recognition receptor (PRR), assembly of the inflammasome complex, leading to the activation of CASP1 and inducing an inflammatory response. In some cases, inflammasome-mediated signal transduction can lead to programmed cell death, such as pyroptosis.
GO:0141085	regulation of inflammasome-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an inflammasome-mediated signaling pathway.
GO:0141086	negative regulation of inflammasome-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway.
GO:0141087	positive regulation of inflammasome-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.
GO:0141088	symbiont-mediated activation of host autophagy	biological_process	A process in which a symbiont initiates, promotes, or enhances the activation of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:0141089	glucose sensor activity	molecular_function	Binding to and responding, e.g. by conformational change, to changes in the cellular level of glucose.
GO:0150001	primary dendrite	cellular_component	A dendrite emerging from the cell body (the soma) of a neuron.
GO:0150002	distal dendrite	cellular_component	The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).
GO:0150003	regulation of spontaneous synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.
GO:0150004	dendritic spine origin	cellular_component	The part of the dendritic spine neck where the spine arises from the dendritic shaft.
GO:0150005	enzyme activator complex	cellular_component	A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.
GO:0150006	urease activator complex	cellular_component	A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.
GO:0150007	clathrin-dependent synaptic vesicle endocytosis	biological_process	Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.
GO:0150008	bulk synaptic vesicle endocytosis	biological_process	Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.
GO:0150011	regulation of neuron projection arborization	biological_process	Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
GO:0150012	positive regulation of neuron projection arborization	biological_process	Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
GO:0150013	negative regulation of neuron projection arborization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
GO:0150014	apical distal dendrite	cellular_component	Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).
GO:0150015	apical proximal dendrite	cellular_component	The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma).
GO:0150016	basal distal dendrite	cellular_component	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).
GO:0150017	basal proximal dendrite	cellular_component	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).
GO:0150018	basal dendrite development	biological_process	The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.
GO:0150019	basal dendrite morphogenesis	biological_process	The process in which the anatomical structures of a basal dendrite are generated and organized.
GO:0150020	basal dendrite arborization	biological_process	The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.
GO:0150021	apical dendrite morphogenesis	biological_process	The process in which the anatomical structures of an apical dendrite are generated and organized.
GO:0150022	apical dendrite development	biological_process	The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.
GO:0150023	apical dendrite arborization	biological_process	The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.
GO:0150024	oxidised low-density lipoprotein particle clearance	biological_process	The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
GO:0150025	oxidised low-density lipoprotein particle receptor activity	molecular_function	Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.
GO:0150031	regulation of protein localization to lysosome	biological_process	Any process that modulates the frequency, rate or extent of protein localization to lysosome.
GO:0150032	positive regulation of protein localization to lysosome	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.
GO:0150033	negative regulation of protein localization to lysosome	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.
GO:0150034	distal axon	cellular_component	That part of an axon close to and including the growth cone or the axon terminus.
GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.
GO:0150036	regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.
GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	biological_process	Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.
GO:0150038	postsynaptic dense core vesicle exocytosis	biological_process	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.
GO:0150043	structural constituent of synapse-associated extracellular matrix	molecular_function	The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.
GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.
GO:0150045	regulation of synaptic signaling by nitric oxide	biological_process	Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.
GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	molecular_function	G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.
GO:0150048	cerebellar granule cell to Purkinje cell synapse	cellular_component	A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.
GO:0150050	postsynaptic septin cytoskeleton	cellular_component	The portion of the septin cytoskeleton contained within the postsynapse.
GO:0150051	postsynaptic Golgi apparatus	cellular_component	The network of the Golgi apparatus structures located within the postsynapse.
GO:0150052	regulation of postsynapse assembly	biological_process	Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.
GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	cellular_component	A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.
GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.
GO:0150056	amylin receptor complex 1	cellular_component	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).
GO:0150057	amylin receptor complex 2	cellular_component	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).
GO:0150058	amylin receptor complex 3	cellular_component	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways.
GO:0150059	amylin receptor 1 signaling pathway	biological_process	The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).
GO:0150060	amylin receptor 2 signaling pathway	biological_process	The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).
GO:0150061	amylin receptor 3 signaling pathway	biological_process	The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.
GO:0150062	complement-mediated synapse pruning	biological_process	Synaptic pruning mediated by complement system signaling.
GO:0150063	visual system development	biological_process	The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.
GO:0150064	vertebrate eye-specific patterning	biological_process	Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus.
GO:0150065	regulation of deacetylase activity	biological_process	Any process that modulates the frequency, rate or extent of deacetylase activity.
GO:0150066	negative regulation of deacetylase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.
GO:0150067	regulation of tubulin deacetylase activity	biological_process	Any process that modulates the frequency, rate or extent of tubulin deacetylase activity.
GO:0150068	positive regulation of tubulin deacetylase activity	biological_process	Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity.
GO:0150069	negative regulation of tubulin deacetylase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity.
GO:0150070	regulation of arginase activity	biological_process	Any process that modulates the frequency, rate or extent of arginase activity.
GO:0150071	negative regulation of arginase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity.
GO:0150072	positive regulation of arginase activity	biological_process	Any process that activates or increases the frequency, rate or extent of arginase activity.
GO:0150073	regulation of protein-glutamine gamma-glutamyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.
GO:0150074	positive regulation of protein-glutamine gamma-glutamyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.
GO:0150075	negative regulation of protein-glutamine gamma-glutamyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.
GO:0150076	neuroinflammatory response	biological_process	The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.
GO:0150077	regulation of neuroinflammatory response	biological_process	Any process that modulates the frequency, rate or extent of neuroinflammatory response.
GO:0150078	positive regulation of neuroinflammatory response	biological_process	Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.
GO:0150079	negative regulation of neuroinflammatory response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.
GO:0150086	multiple synapse bouton	cellular_component	A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.
GO:0150087	multiple synapse bouton, contacting single dendrite	cellular_component	A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.
GO:0150088	multiple synapse bouton, contacting multiple dendrites	cellular_component	A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.
GO:0150089	multiple spine synapse organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.
GO:0150090	multiple spine synapse organization, single dendrite	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.
GO:0150091	multiple spine synapse organization, multiple dendrites	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.
GO:0150092	regulation of synaptic scaling	biological_process	A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.
GO:0150093	amyloid-beta clearance by transcytosis	biological_process	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.
GO:0150094	amyloid-beta clearance by cellular catabolic process	biological_process	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.
GO:0150098	glial cell-neuron signaling	biological_process	Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.
GO:0150099	neuron-glial cell signaling	biological_process	Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.
GO:0150101	regulation of microtubule anchoring at centrosome	biological_process	Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.
GO:0150102	negative regulation of monocyte activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.
GO:0150103	reactive gliosis	biological_process	A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells.
GO:0150104	transport across blood-brain barrier	biological_process	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.
GO:0150105	protein localization to cell-cell junction	biological_process	A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.
GO:0150106	regulation of protein localization to cell-cell junction	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.
GO:0150107	positive regulation of protein localization to cell-cell junction	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.
GO:0150111	regulation of transepithelial transport	biological_process	Any process that modulates the frequency, rate or extent of transepithelial transport.
GO:0150115	cell-substrate junction organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.
GO:0150116	regulation of cell-substrate junction organization	biological_process	Any process that modulates the frequency, rate or extent of cell-substrate junction organization.
GO:0150117	positive regulation of cell-substrate junction organization	biological_process	Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization.
GO:0150118	negative regulation of cell-substrate junction organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.
GO:0150119	negative regulation of protein localization to cell-cell junction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.
GO:0150127	regulation of interleukin-33 production	biological_process	Any process that modulates the frequency, rate or extent of interleukin-33 production.
GO:0150128	negative regulation of interleukin-33 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.
GO:0150129	positive regulation of interleukin-33 production	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-33 production.
GO:0150136	regulation of interleukin-37 production	biological_process	Any process that modulates the frequency, rate or extent of interleukin-37 production.
GO:0150137	interleukin-37 production	biological_process	The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0150138	negative regulation of interleukin-37 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.
GO:0150139	positive regulation of interleukin-37 production	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-37 production.
GO:0150140	regulation of CD86 production	biological_process	Any process that modulates the frequency, rate or extent of CD86 biosynthetic process.
GO:0150141	negative regulation of CD86 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process.
GO:0150142	positive regulation of CD86 production	biological_process	Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process.
GO:0150143	regulation of CD80 production	biological_process	Any process that modulates the frequency, rate or extent of CD80 biosynthetic process.
GO:0150144	negative regulation of CD80 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process.
GO:0150145	positive regulation of CD80 production	biological_process	Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process.
GO:0150146	cell junction disassembly	biological_process	The disaggregation of a cell junction into its constituent components.
GO:0150147	cell-cell junction disassembly	biological_process	The disaggregation of a cell-cell junction into its constituent components.
GO:0150151	regulation of interleukin-17A production	biological_process	Any process that modulates the frequency, rate or extent of interleukin-17A production.
GO:0150152	negative regulation of interleukin-17A production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.
GO:0150153	positive regulation of interleukin-17A production	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-17A production.
GO:0150155	interleukin-34 production	biological_process	The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0150157	regulation of interleukin-34 production	biological_process	Any process that modulates the frequency, rate or extent of interleukin-34 production.
GO:0150158	positive regulation of interleukin-34 production	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-34 production.
GO:0150159	negative regulation of interleukin-34 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.
GO:0150172	regulation of phosphatidylcholine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.
GO:0150173	positive regulation of phosphatidylcholine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process.
GO:0150174	negative regulation of phosphatidylcholine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.
GO:0150175	regulation of phosphatidylethanolamine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.
GO:0150176	positive regulation of phosphatidylethanolamine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.
GO:0150177	negative regulation of phosphatidylethanolamine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process.
GO:0150178	regulation of phosphatidylserine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.
GO:0150179	positive regulation of phosphatidylserine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process.
GO:0150180	negative regulation of phosphatidylserine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.
GO:0150189	regulation of interleukin-32 production	biological_process	Any process that modulates the frequency, rate or extent of interleukin-32 production.
GO:0150190	negative regulation of interleukin-32 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.
GO:0150191	positive regulation of interleukin-32 production	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-32 production.
GO:0150195	transport across blood-cerebrospinal fluid barrier	biological_process	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.
GO:0150200	regulation of transport across blood-brain barrier	biological_process	Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.
GO:0150201	positive regulation of transport across blood-brain barrier	biological_process	Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.
GO:0150202	negative regulation of transport across blood-brain barrier	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.
GO:0160001	extrasynaptic signaling via GABA	biological_process	Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.
GO:0160002	ADP-D-ribose modification-dependent protein binding	molecular_function	Binding to a protein upon ADP-ribosylation of the target protein.
GO:0160003	mono-ADP-D-ribose modification-dependent protein binding	molecular_function	Binding to a protein upon mono-ADP-ribosylation of the target protein.
GO:0160004	poly-ADP-D-ribose modification-dependent protein binding	molecular_function	Binding to a protein upon poly-ADP-ribosylation of the target protein.
GO:0160005	PAT complex	cellular_component	A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47.
GO:0160006	Fc receptor-mediated immune complex endocytosis	biological_process	An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I.
GO:0160007	glutathione import into mitochondrion	biological_process	The process in which glutathione is transported from the cytosol into the mitochondrial matrix.
GO:0160008	protein decrotonylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein].
GO:0160009	histone decrotonylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] = (2E)-2-butenoate + L-lysyl-[histone].
GO:0160010	protein de-2-hydroxyisobutyrylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein].
GO:0160011	NAD-dependent protein decrotonylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0160012	NAD-dependent histone decrotonylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone] + nicotinamide.
GO:0160013	NAD-dependent protein de-2-hydroxyisobutyrylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
GO:0160014	exopher	cellular_component	An extracellular vesicle that is approximately four microns in diameter, released by budding out of cells into the extracellular space, and hypothesized to be a mechanism for disposal of unwanted cellular material including protein aggregates and damaged organelles.
GO:0160015	platelet rolling	biological_process	Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium.
GO:0160016	CCACCA tRNA nucleotidyltransferase activity	molecular_function	Catalysis of the reaction: an unstable tRNA + 2 ATP + 4 CTP = a tRNA with a 3' CCACCA end + 6 diphosphate.
GO:0160017	regulation of platelet rolling	biological_process	Any process that modulates the frequency, rate or extent of platelet rolling.
GO:0160018	positive regulation of platelet rolling	biological_process	Any process that increases the rate, frequency, or extent of platelet rolling.
GO:0160019	negative regulation of platelet rolling	biological_process	Any process that decreases the rate, frequency, or extent of platelet rolling.
GO:0160020	positive regulation of ferroptosis	biological_process	Any process that activates or increases the frequency, rate or extent of ferroptosis.
GO:0160021	maternal-to-zygotic transition of gene expression	biological_process	Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome.
GO:0160022	apocrine secretion	biological_process	The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm.
GO:0160023	sneeze reflex	biological_process	A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane.
GO:0160024	Leydig cell proliferation	biological_process	The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone.
GO:0160025	sensory perception of itch	biological_process	A sensory perception which causes the desire or reflex to scratch.
GO:0160027	egg deposition	biological_process	The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment.
GO:0160028	negative regulation of pyroptosis	biological_process	Any process that decreases the frequency, rate or extent of pyroptosis.
GO:0160029	kidney cortex tubule cell dedifferentiation	biological_process	The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
GO:0160030	pollen intine formation	biological_process	Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine.
GO:0160031	endoplasmic reticulum membrane biogenesis	biological_process	The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together.
GO:0160032	Toll receptor ligand protein activation cascade	biological_process	A protein activation cascade that generates the active Toll receptor ligand and consists of the cascade of enzymatic reactions initiated by extracellular recognition factors, leading to the cleavage of the inactive form of spatzle family of ligands.
GO:0160033	regulation of Toll receptor ligand protein activation cascade	biological_process	Any process that modulates the frequency, rate or extent of the Toll receptor ligand protein activation cascade.
GO:0160034	positive regulation of Toll receptor ligand protein activation cascade	biological_process	Any process that activates or increases the frequency, rate or extent of Toll receptor ligand protein activation cascade.
GO:0160035	negative regulation of Toll receptor ligand protein activation cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Toll receptor ligand protein activation cascade.
GO:0160036	positive regulation of postsynaptic density assembly	biological_process	Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly.
GO:0160037	negative regulation of postsynaptic density assembly	biological_process	Any process that decreases the rate, frequency, or extent of postsynaptic density assembly.
GO:0160038	somatic sensory system development	biological_process	The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain.
GO:0160039	serotonin-gated chloride channel activity	molecular_function	Enables the transmembrane transfer of a chloride ion by a channel that opens when the biogenic amine serotonin has been bound by the channel complex or one of its constituent parts. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
GO:0160040	mitocytosis	biological_process	A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells.
GO:0160041	neuropeptide activity	molecular_function	The receptor ligand activity of any polypeptide expressed in, and secreted from a neuron.
GO:0160042	purine nucleotide uniporter activity	molecular_function	Catalysis of the active transport of purine nucleotides across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
GO:0160043	catecholamine secretion, neurotransmission	biological_process	The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter.
GO:0160044	sulfate:chloride antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + sulfate(out) = chloride(out) + sulfate(in).
GO:0160045	TMEM240-body	cellular_component	A multilamellar subcellular structure formed in the cytoplasm of developing neuron, composed of Tmem240 and Emd proteins.
GO:0160046	oxalate:chloride antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + oxalate(in) = chloride(in) + oxalate(out).
GO:0160047	muramyl dipeptide kinase activity	molecular_function	Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H(+) + 6-O-phospho-muramyl dipeptide.
GO:0160048	craniofacial suture closure	biological_process	The process of fusing together the edges of a craniofacial suture.
GO:0160049	negative regulation of cGAS/STING signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway.
GO:0160050	xanthine binding	molecular_function	Binding to xanthine, a purine base.
GO:0160051	Cyc8(Ssn6)-Tup1 general repressor complex	cellular_component	A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters.
GO:0160052	mitotic nuclear envelope segregation	biological_process	The mitotic cell cycle process in which the nuclear envelope, including nuclear pores, is equally distributed to the two daughter cells during the mitotic cell cycle.
GO:0160053	serine-based site-specific recombinase activity	molecular_function	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphoseryl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a serine in the active site.
GO:0160054	microfibril assembly	biological_process	The aggregation, arrangement and bonding together of microfibril.
GO:0160055	glideosome	cellular_component	A protein complex composed of at least GAP45 (gliding-associated protein), GAP50 and myosin heavy and light chains. Anchored via GAP50 to the inner membrane complex of motile and invasive forms of apicomplexan parasites and regulates parasite gliding motility and invasion of host cells.
GO:0160056	macropinosome membrane	cellular_component	The lipid bilayer surrounding a macropinosome.
GO:0160057	plant endodermal cell fate specification	biological_process	The process in which a cell becomes capable of differentiating autonomously into a plant endodermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
GO:0160058	plant endodermal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires specialized features of a plant endodermal cell.
GO:0160059	programmed cell death in response to retinoic acid	biological_process	Cell death resulting from activation of endogenous cellular processes and occurring as a result of a retinoic acid.
GO:0160060	sleep homeostasis	biological_process	A homeostatic process in which the drive for sleep increases sleep propensity with prolonged wakefulness.
GO:0160061	respiratory chemosensitivity	biological_process	A homeostatic process by which the sensing of CO2 and/or H+ by the brain leads to appropriate altering in breathing to regulate blood gas and tissue pH.
GO:0160062	cutin-based cuticle development	biological_process	The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. Cutin-based cuticle is an extracellular structure composed of a covalently linked macromolecular scaffold of cutin and a variety of organic solvent-soluble lipids that are collectively termed waxes. Such structures are found on the external face of polysaccharide cell walls in land plants.
GO:0160063	multi-pass transmembrane protein insertion into ER membrane	biological_process	A process of protein insertion of multi-pass membrane proteins into the endoplasmic reticulum (ER) membrane. Insertion of multi-pass membrane proteins is mediated by the multi-pass translocon complex and takes place following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex to promote insertion of subsequent transmembrane regions.
GO:0160064	multi-pass translocon complex	cellular_component	A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47).
GO:0160065	SIN/MEN signaling complex	cellular_component	A protein complex associated with the mitotic spindle pole body during interphase and mitosis and comprises of the proteins of the septation initiation signaling network (SIN) of fission yeast or mitotic exit network (MEN) of budding yeast, organized by two scaffold/adaptor proteins.
GO:0160066	interphase SIN signaling complex	cellular_component	A SIN signaling complex associated with the old mitotic spindle pole body during interphase and early M-phase and characterised by the presence active ubiquitin ligase (Dma1 in fission yeast) and GTPase activator (Spg1 in fission yeast) to inactivate SIN signaling.
GO:0160067	new spindle pole body SIN signaling complex	cellular_component	A SIN signaling complex associated with the new mitotic spindle pole body during anaphase and characterized by the presence activated (GTP bound) GTPase (Spg1 in fission yeast) to activate SIN signaling.
GO:0160068	negative regulation of pollen tube guidance	biological_process	Any process that decreases the rate, frequency or extent of pollen tube guidance towards ovules. This is one mechanism to prevent polytuby, the simultaneous penetration of ovules by multiple pollen tubes.
GO:0160069	surfactant secretion	biological_process	The regulated release of surfactant by a cell or tissue.
GO:0160070	intracellular borate homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell.
GO:0160071	prevention of polyspermy during double fertilization	biological_process	The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell.
GO:0160072	ubiquitin ligase complex scaffold activity	molecular_function	The binding activity of a molecule that brings together an ubiquitin ligase and an ubiquitin ligase-substrate adaptor, permitting those molecules to function in a coordinated way.
GO:0160073	Casparian strip assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Casparian strip, a region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material.
GO:0160074	non-canonical inflammasome complex	cellular_component	An inflammasome complex containing CASP4, known as caspase-11 (Casp11) in mouse, which assembles upon cytosolic lipopolysaccharide-binding and directly activates Gasdermin-D (GSDMD).
GO:0160075	non-canonical inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a non-canonical inflammasome complex.
GO:0160076	negative regulation of non-canonical inflammasome complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical inflammasome complex assembly.
GO:0160077	lipid droplet fusion	biological_process	The process by which a single lipid droplet is created from the fusion of two or more lipid droplets.
GO:0160078	negative regulation of lipid droplet fusion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of lipid droplet fusion.
GO:0160079	metabotropic glycine receptor activity	molecular_function	Combining with glycine and transmitting the signal across the membrane by changing the activity of intracellular G protein signaling.
GO:0160080	ABC-type indole transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + indole(in) = ADP + phosphate + indole(out).
GO:0160081	iodide channel activity	molecular_function	Enables the facilitated diffusion of a iodide (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
GO:0160082	hypoxia-inducible factor-proline dioxygenase activity	molecular_function	Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].
GO:0170001	ergothioneine transmembrane transporter activity	molecular_function	Enables the transfer of ergothioneine from one side of a membrane to the other.
GO:0170002	halotropism	biological_process	A sodium-specific negative tropism that is crucial for surviving and thriving under high salinity.
GO:0170003	heme B transmembrane transporter activity	molecular_function	Enables the transfer of heme B from one side of a membrane to the other.
GO:0170004	lipoate transmembrane transporter activity	molecular_function	Enables the transfer of lipoate from one side of a membrane to the other.
GO:0170005	cyclic nucleotide phosphodiesterase activator activity	molecular_function	Binds to and increases the activity of cyclic nucleotide phosphodiesterase.
GO:0170006	lipoate transmembrane transport	biological_process	The process in which lipoate is transported across a membrane.
GO:0170007	endoplasmic reticulum-lipid droplet tether activity	molecular_function	The binding activity of a molecule that brings together a lipid droplet with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication.
GO:0170008	mRNA phosphatase activator activity	molecular_function	Binds to and increases the activity of mRNA phosphatase.
GO:0170009	endoplasmic reticulum-organelle membrane tether activity	molecular_function	The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication.
GO:0170010	nonsense-mediated decay complex	cellular_component	A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
GO:0170011	stalled ribosome sensor activity	molecular_function	A molecule that recognizes stalled ribosomes and initiates a signaling response.
GO:0170012	histone H3K18 decrotonylase activity	molecular_function	Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide.
GO:0170013	channel complex	cellular_component	A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
GO:0170014	ankyrin-1 complex	cellular_component	A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human.
GO:0170015	carbon dioxide receptor activity	molecular_function	Combining with carbon dioxide to initiate a change in cell activity.
GO:0170016	endoplasmic reticulum-endosome tether activity	molecular_function	The binding activity of a molecule that brings together an endosome and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange.
GO:0170020	ionotropic olfactory receptor activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific odorant has been bound by the channel complex or one of its constituent parts.
GO:0170021	ionotropic taste receptor activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a soluble compound has been bound by the channel complex or one of its constituent parts.
GO:0170022	ionotropic bitter taste receptor activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts.
GO:0170023	ionotropic sweet taste receptor activity	molecular_function	Enables the transmembrane transfer of an ion by a channel that opens when a specific soluble sweet compound has been bound by the channel complex or one of its constituent parts.
GO:0180000	histone methyltransferase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a histone methyltransferase.
GO:0180001	cyclic-di-AMP binding	molecular_function	Binding to a cyclic di-AMP nucleotide.
GO:0180002	renal zinc excretion	biological_process	The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
GO:0180003	S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) = S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out).
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate.
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate.
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate.
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate.
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	molecular_function	Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate.
GO:0180009	broad specificity neutral L-amino acid:basic L-amino acid antiporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: basic L-amino acid(in) + neutral L-amino acid(out) = basic L-amino acid(in) + neutral L-amino acid(out).
GO:0180010	co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	biological_process	Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage  and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional mRNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay.
GO:0180011	cytoplasmic polyadenylation	biological_process	Any process by which dormant, translationally inactive mRNAs become activated via the elongation of their poly(A) tails in the cytosol.
GO:0180012	co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway	biological_process	Any process involved in transcription termination-coupled  3' processing of RNA polymerase II RNA transcripts by 3' end cleavage  and addition of a poly(A) tail. This pathway is required for the maturation of primary protein-encoding transcripts into functional RNAs that can be exported from the nucleus and translated in the cytoplasm, but is also required for polyadenylation-dependent decay.
GO:0180013	lysophosphatidylserine flippase activity	molecular_function	Catalysis of the movement of a lysophosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.
GO:0180014	protein-tRNA adaptor activity	molecular_function	The binding activity of a protein that brings together another protein and a tRNA, permitting those molecules to function in a coordinated way.
GO:0180015	nucleoside import across plasma membrane	biological_process	The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol.
GO:0180016	SUMO ligase regulator activity	molecular_function	Binds to and modulates the activity of a SUMO ligase.
GO:0180017	K11-linked deubiquitinase activity	molecular_function	Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys11 residue of ubiquitin.
GO:0180018	cytoplasmic polyadenylation-dependent RNA catabolic process	biological_process	The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.
GO:0180019	Knl1/Spc105 complex	cellular_component	A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p.
GO:0180020	membrane bending activity	molecular_function	The activity of bending or deforming a membrane. This activity can occur by multiple mechanisms including the insertion amphipathic domains into one or both leaflets.
GO:0180021	snRNA 2'-O-ribose methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + snRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.
GO:0198738	cell-cell signaling by wnt	biological_process	Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell.
GO:1900000	regulation of anthocyanin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.
GO:1900001	negative regulation of anthocyanin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.
GO:1900002	positive regulation of anthocyanin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.
GO:1900003	regulation of serine-type endopeptidase activity	biological_process	Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.
GO:1900004	negative regulation of serine-type endopeptidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.
GO:1900005	positive regulation of serine-type endopeptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.
GO:1900006	positive regulation of dendrite development	biological_process	Any process that activates or increases the frequency, rate or extent of dendrite development.
GO:1900010	regulation of corticotropin-releasing hormone receptor activity	biological_process	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
GO:1900011	negative regulation of corticotropin-releasing hormone receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
GO:1900012	positive regulation of corticotropin-releasing hormone receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
GO:1900015	regulation of cytokine production involved in inflammatory response	biological_process	Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.
GO:1900016	negative regulation of cytokine production involved in inflammatory response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
GO:1900017	positive regulation of cytokine production involved in inflammatory response	biological_process	Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
GO:1900019	regulation of protein kinase C activity	biological_process	Any process that modulates the frequency, rate or extent of protein kinase C activity.
GO:1900020	positive regulation of protein kinase C activity	biological_process	Any process that activates or increases the frequency, rate or extent of protein kinase C activity.
GO:1900022	regulation of D-erythro-sphingosine kinase activity	biological_process	Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity.
GO:1900023	positive regulation of D-erythro-sphingosine kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity.
GO:1900024	regulation of substrate adhesion-dependent cell spreading	biological_process	Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	biological_process	Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
GO:1900027	regulation of ruffle assembly	biological_process	Any process that modulates the frequency, rate or extent of ruffle assembly.
GO:1900028	negative regulation of ruffle assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.
GO:1900029	positive regulation of ruffle assembly	biological_process	Any process that activates or increases the frequency, rate or extent of ruffle assembly.
GO:1900030	regulation of pectin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of pectin biosynthetic process.
GO:1900032	regulation of trichome patterning	biological_process	Any process that modulates the frequency, rate or extent of trichome patterning.
GO:1900033	negative regulation of trichome patterning	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning.
GO:1900034	regulation of cellular response to heat	biological_process	Any process that modulates the frequency, rate or extent of cellular response to heat.
GO:1900035	negative regulation of cellular response to heat	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.
GO:1900036	positive regulation of cellular response to heat	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to heat.
GO:1900037	regulation of cellular response to hypoxia	biological_process	Any process that modulates the frequency, rate or extent of cellular response to hypoxia.
GO:1900038	negative regulation of cellular response to hypoxia	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.
GO:1900039	positive regulation of cellular response to hypoxia	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia.
GO:1900044	regulation of protein K63-linked ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.
GO:1900045	negative regulation of protein K63-linked ubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination.
GO:1900046	regulation of hemostasis	biological_process	Any process that modulates the frequency, rate or extent of hemostasis.
GO:1900047	negative regulation of hemostasis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.
GO:1900048	positive regulation of hemostasis	biological_process	Any process that activates or increases the frequency, rate or extent of hemostasis.
GO:1900052	regulation of retinoic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.
GO:1900053	negative regulation of retinoic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process.
GO:1900054	positive regulation of retinoic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.
GO:1900055	regulation of leaf senescence	biological_process	Any process that modulates the frequency, rate or extent of leaf senescence.
GO:1900056	negative regulation of leaf senescence	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.
GO:1900057	positive regulation of leaf senescence	biological_process	Any process that activates or increases the frequency, rate or extent of leaf senescence.
GO:1900058	regulation of sulfate assimilation	biological_process	Any process that modulates the frequency, rate or extent of sulfate assimilation.
GO:1900059	positive regulation of sulfate assimilation	biological_process	Any process that activates or increases the frequency, rate or extent of sulfate assimilation.
GO:1900060	negative regulation of ceramide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.
GO:1900063	regulation of peroxisome organization	biological_process	Any process that modulates the frequency, rate or extent of peroxisome organization.
GO:1900064	positive regulation of peroxisome organization	biological_process	Any process that activates or increases the frequency, rate or extent of peroxisome organization.
GO:1900065	regulation of ethanol catabolic process	biological_process	Any process that modulates the frequency, rate or extent of ethanol catabolic process.
GO:1900066	positive regulation of ethanol catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ethanol catabolic process.
GO:1900067	regulation of cellular response to alkaline pH	biological_process	Any process that modulates the frequency, rate or extent of cellular response to alkalinity.
GO:1900068	negative regulation of cellular response to alkaline pH	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.
GO:1900069	regulation of cellular hyperosmotic salinity response	biological_process	Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
GO:1900070	negative regulation of cellular hyperosmotic salinity response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.
GO:1900071	regulation of sulfite transport	biological_process	Any process that modulates the frequency, rate or extent of sulfite transport.
GO:1900072	positive regulation of sulfite transport	biological_process	Any process that activates or increases the frequency, rate or extent of sulfite transport.
GO:1900073	regulation of neuromuscular synaptic transmission	biological_process	Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
GO:1900074	negative regulation of neuromuscular synaptic transmission	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.
GO:1900075	positive regulation of neuromuscular synaptic transmission	biological_process	Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
GO:1900076	regulation of cellular response to insulin stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.
GO:1900077	negative regulation of cellular response to insulin stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.
GO:1900078	positive regulation of cellular response to insulin stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
GO:1900079	regulation of arginine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of arginine biosynthetic process.
GO:1900080	positive regulation of arginine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process.
GO:1900081	regulation of arginine catabolic process	biological_process	Any process that modulates the frequency, rate or extent of arginine catabolic process.
GO:1900082	negative regulation of arginine catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process.
GO:1900084	regulation of peptidyl-tyrosine autophosphorylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	biological_process	Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
GO:1900088	regulation of inositol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of inositol biosynthetic process.
GO:1900089	negative regulation of inositol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process.
GO:1900090	positive regulation of inositol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process.
GO:1900091	regulation of raffinose biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.
GO:1900092	negative regulation of raffinose biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.
GO:1900093	positive regulation of raffinose biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process.
GO:1900095	regulation of dosage compensation by inactivation of X chromosome	biological_process	Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
GO:1900096	negative regulation of dosage compensation by inactivation of X chromosome	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
GO:1900097	positive regulation of dosage compensation by inactivation of X chromosome	biological_process	Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
GO:1900098	regulation of plasma cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of plasma cell differentiation.
GO:1900099	negative regulation of plasma cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.
GO:1900100	positive regulation of plasma cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	biological_process	Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	biological_process	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
GO:1900104	regulation of hyaluranon cable assembly	biological_process	Any process that modulates the frequency, rate or extent of hyaluranon cable assembly.
GO:1900105	negative regulation of hyaluranon cable assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly.
GO:1900106	positive regulation of hyaluranon cable assembly	biological_process	Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.
GO:1900107	regulation of nodal signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of nodal signaling pathway.
GO:1900108	negative regulation of nodal signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.
GO:1900109	regulation of histone H3-K9 dimethylation	biological_process	Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation.
GO:1900110	negative regulation of histone H3-K9 dimethylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation.
GO:1900111	positive regulation of histone H3-K9 dimethylation	biological_process	Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation.
GO:1900112	regulation of histone H3-K9 trimethylation	biological_process	Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation.
GO:1900113	negative regulation of histone H3-K9 trimethylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation.
GO:1900114	positive regulation of histone H3-K9 trimethylation	biological_process	Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation.
GO:1900115	extracellular regulation of signal transduction	biological_process	Any regulation of signal transduction that takes place in the extracellular region.
GO:1900116	extracellular negative regulation of signal transduction	biological_process	Any negative regulation of signal transduction that takes place in extracellular region.
GO:1900117	regulation of execution phase of apoptosis	biological_process	Any process that modulates the frequency, rate or extent of execution phase of apoptosis.
GO:1900118	negative regulation of execution phase of apoptosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
GO:1900119	positive regulation of execution phase of apoptosis	biological_process	Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.
GO:1900120	regulation of receptor binding	biological_process	Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.
GO:1900121	negative regulation of receptor binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.
GO:1900122	positive regulation of receptor binding	biological_process	Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.
GO:1900123	regulation of nodal receptor complex assembly	biological_process	Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.
GO:1900124	negative regulation of nodal receptor complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly.
GO:1900125	regulation of hyaluronan biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.
GO:1900126	negative regulation of hyaluronan biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.
GO:1900127	positive regulation of hyaluronan biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.
GO:1900128	regulation of G-protein activated inward rectifier potassium channel activity	biological_process	Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.
GO:1900129	positive regulation of G-protein activated inward rectifier potassium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.
GO:1900130	regulation of lipid binding	biological_process	Any process that modulates the frequency, rate or extent of lipid binding.
GO:1900131	negative regulation of lipid binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
GO:1900132	positive regulation of lipid binding	biological_process	Any process that activates or increases the frequency, rate or extent of lipid binding.
GO:1900133	regulation of renin secretion into blood stream	biological_process	Any process that modulates the frequency, rate or extent of renin secretion into blood stream.
GO:1900134	negative regulation of renin secretion into blood stream	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.
GO:1900135	positive regulation of renin secretion into blood stream	biological_process	Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.
GO:1900136	regulation of chemokine activity	biological_process	Any process that modulates the frequency, rate or extent of chemokine activity.
GO:1900137	negative regulation of chemokine activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.
GO:1900138	negative regulation of phospholipase A2 activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.
GO:1900139	negative regulation of arachidonic acid secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
GO:1900140	regulation of seedling development	biological_process	Any process that modulates the frequency, rate or extent of seedling development.
GO:1900141	regulation of oligodendrocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.
GO:1900142	negative regulation of oligodendrocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.
GO:1900143	positive regulation of oligodendrocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.
GO:1900144	positive regulation of BMP secretion	biological_process	Any process that activates or increases the frequency, rate or extent of BMP secretion.
GO:1900145	regulation of nodal signaling pathway involved in determination of left/right asymmetry	biological_process	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.
GO:1900146	negative regulation of nodal signaling pathway involved in determination of left/right asymmetry	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.
GO:1900147	regulation of Schwann cell migration	biological_process	Any process that modulates the frequency, rate or extent of Schwann cell migration.
GO:1900148	negative regulation of Schwann cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.
GO:1900149	positive regulation of Schwann cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of Schwann cell migration.
GO:1900150	regulation of defense response to fungus	biological_process	Any process that modulates the frequency, rate or extent of defense response to fungus.
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological_process	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	biological_process	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
GO:1900154	regulation of bone trabecula formation	biological_process	Any process that modulates the frequency, rate or extent of bone trabecula formation.
GO:1900155	negative regulation of bone trabecula formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.
GO:1900156	positive regulation of bone trabecula formation	biological_process	Any process that activates or increases the frequency, rate or extent of bone trabecula formation.
GO:1900157	regulation of bone mineralization involved in bone maturation	biological_process	Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.
GO:1900158	negative regulation of bone mineralization involved in bone maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.
GO:1900159	positive regulation of bone mineralization involved in bone maturation	biological_process	Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.
GO:1900160	plastid chromosome packaging	biological_process	A process in which plastidial DNA and associated proteins organize into a compact, orderly structure.
GO:1900161	regulation of phospholipid scramblase activity	biological_process	Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.
GO:1900162	negative regulation of phospholipid scramblase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.
GO:1900163	positive regulation of phospholipid scramblase activity	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.
GO:1900164	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	biological_process	The series of molecular signals initiated by a nodal protein binding to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
GO:1900166	regulation of glial cell-derived neurotrophic factor production	biological_process	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production.
GO:1900167	negative regulation of glial cell-derived neurotrophic factor production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.
GO:1900168	positive regulation of glial cell-derived neurotrophic factor production	biological_process	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production.
GO:1900169	regulation of glucocorticoid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway.
GO:1900170	negative regulation of glucocorticoid mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.
GO:1900171	positive regulation of glucocorticoid mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway.
GO:1900175	regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	biological_process	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.
GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.
GO:1900177	regulation of aflatoxin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.
GO:1900178	negative regulation of aflatoxin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.
GO:1900179	positive regulation of aflatoxin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.
GO:1900180	regulation of protein localization to nucleus	biological_process	Any process that modulates the frequency, rate or extent of protein localization to nucleus.
GO:1900181	negative regulation of protein localization to nucleus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
GO:1900182	positive regulation of protein localization to nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
GO:1900183	regulation of xanthone-containing compound biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process.
GO:1900184	negative regulation of xanthone-containing compound biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process.
GO:1900185	positive regulation of xanthone-containing compound biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process.
GO:1900186	negative regulation of clathrin-dependent endocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.
GO:1900187	regulation of cell adhesion involved in single-species biofilm formation	biological_process	Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
GO:1900188	negative regulation of cell adhesion involved in single-species biofilm formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
GO:1900189	positive regulation of cell adhesion involved in single-species biofilm formation	biological_process	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
GO:1900190	regulation of single-species biofilm formation	biological_process	Any process that modulates the frequency, rate or extent of single-species biofilm formation.
GO:1900191	negative regulation of single-species biofilm formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
GO:1900192	positive regulation of single-species biofilm formation	biological_process	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.
GO:1900193	regulation of oocyte maturation	biological_process	Any process that modulates the frequency, rate or extent of oocyte maturation.
GO:1900194	negative regulation of oocyte maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
GO:1900195	positive regulation of oocyte maturation	biological_process	Any process that activates or increases the frequency, rate or extent of oocyte maturation.
GO:1900196	regulation of penicillin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of penicillin biosynthetic process.
GO:1900197	negative regulation of penicillin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.
GO:1900198	positive regulation of penicillin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process.
GO:1900199	positive regulation of protein export from nucleus during meiotic anaphase II	biological_process	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.
GO:1900200	mesenchymal cell apoptotic process involved in metanephros development	biological_process	Any mesenchymal cell apoptotic process that is involved in metanephros development.
GO:1900204	apoptotic process involved in metanephric collecting duct development	biological_process	Any apoptotic process that is involved in metanephric collecting duct development.
GO:1900205	apoptotic process involved in metanephric nephron tubule development	biological_process	Any apoptotic process that is involved in metanephric nephron tubule development.
GO:1900206	regulation of pronephric nephron tubule development	biological_process	Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.
GO:1900207	negative regulation of pronephric nephron tubule development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.
GO:1900208	regulation of cardiolipin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.
GO:1900209	negative regulation of cardiolipin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.
GO:1900210	positive regulation of cardiolipin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.
GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
GO:1900212	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
GO:1900213	positive regulation of mesenchymal cell apoptotic process involved in metanephros development	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
GO:1900214	regulation of apoptotic process involved in metanephric collecting duct development	biological_process	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
GO:1900215	negative regulation of apoptotic process involved in metanephric collecting duct development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
GO:1900216	positive regulation of apoptotic process involved in metanephric collecting duct development	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
GO:1900217	regulation of apoptotic process involved in metanephric nephron tubule development	biological_process	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
GO:1900218	negative regulation of apoptotic process involved in metanephric nephron tubule development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
GO:1900219	positive regulation of apoptotic process involved in metanephric nephron tubule development	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	biological_process	Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis.
GO:1900221	regulation of amyloid-beta clearance	biological_process	Any process that modulates the frequency, rate or extent of amyloid-beta clearance.
GO:1900222	negative regulation of amyloid-beta clearance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance.
GO:1900223	positive regulation of amyloid-beta clearance	biological_process	Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance.
GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	biological_process	Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry.
GO:1900225	regulation of NLRP3 inflammasome complex assembly	biological_process	Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.
GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.
GO:1900228	regulation of single-species biofilm formation in or on host organism	biological_process	Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.
GO:1900229	negative regulation of single-species biofilm formation in or on host organism	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism.
GO:1900230	positive regulation of single-species biofilm formation in or on host organism	biological_process	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.
GO:1900231	regulation of single-species biofilm formation on inanimate substrate	biological_process	Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GO:1900232	negative regulation of single-species biofilm formation on inanimate substrate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GO:1900233	positive regulation of single-species biofilm formation on inanimate substrate	biological_process	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
GO:1900234	regulation of Kit signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of Kit signaling pathway.
GO:1900235	negative regulation of Kit signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.
GO:1900236	positive regulation of Kit signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.
GO:1900237	positive regulation of induction of conjugation with cellular fusion	biological_process	Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion.
GO:1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.
GO:1900239	regulation of phenotypic switching	biological_process	Any process that modulates the frequency, rate or extent of phenotypic switching.
GO:1900240	negative regulation of phenotypic switching	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.
GO:1900241	positive regulation of phenotypic switching	biological_process	Any process that activates or increases the frequency, rate or extent of phenotypic switching.
GO:1900242	regulation of synaptic vesicle endocytosis	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.
GO:1900243	negative regulation of synaptic vesicle endocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.
GO:1900244	positive regulation of synaptic vesicle endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
GO:1900245	positive regulation of MDA-5 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.
GO:1900246	positive regulation of RIG-I signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.
GO:1900247	regulation of cytoplasmic translational elongation	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.
GO:1900248	negative regulation of cytoplasmic translational elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.
GO:1900249	positive regulation of cytoplasmic translational elongation	biological_process	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.
GO:1900259	regulation of RNA-dependent RNA polymerase activity	biological_process	Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
GO:1900260	negative regulation of RNA-dependent RNA polymerase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
GO:1900261	positive regulation of RNA-dependent RNA polymerase activity	biological_process	Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
GO:1900262	regulation of DNA-directed DNA polymerase activity	biological_process	Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity.
GO:1900263	negative regulation of DNA-directed DNA polymerase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.
GO:1900264	positive regulation of DNA-directed DNA polymerase activity	biological_process	Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.
GO:1900265	regulation of substance P receptor binding	biological_process	Any process that modulates the frequency, rate or extent of substance P receptor binding.
GO:1900266	negative regulation of substance P receptor binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding.
GO:1900267	positive regulation of substance P receptor binding	biological_process	Any process that activates or increases the frequency, rate or extent of substance P receptor binding.
GO:1900268	regulation of reverse transcription	biological_process	Any process that modulates the frequency, rate or extent of reverse transcription.
GO:1900269	negative regulation of reverse transcription	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.
GO:1900270	positive regulation of reverse transcription	biological_process	Any process that activates or increases the frequency, rate or extent of reverse transcription.
GO:1900271	regulation of long-term synaptic potentiation	biological_process	Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.
GO:1900272	negative regulation of long-term synaptic potentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.
GO:1900273	positive regulation of long-term synaptic potentiation	biological_process	Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.
GO:1900274	regulation of phospholipase C activity	biological_process	Any process that modulates the frequency, rate or extent of phospholipase C activity.
GO:1900275	negative regulation of phospholipase C activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity.
GO:1900276	regulation of proteinase activated receptor activity	biological_process	Any process that modulates the frequency, rate or extent of proteinase activated receptor activity.
GO:1900277	negative regulation of proteinase activated receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.
GO:1900278	positive regulation of proteinase activated receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity.
GO:1900279	regulation of CD4-positive, alpha-beta T cell costimulation	biological_process	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
GO:1900280	negative regulation of CD4-positive, alpha-beta T cell costimulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
GO:1900281	positive regulation of CD4-positive, alpha-beta T cell costimulation	biological_process	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
GO:1900282	regulation of cellobiose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellobiose catabolic process.
GO:1900283	negative regulation of cellobiose catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.
GO:1900284	positive regulation of cellobiose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.
GO:1900285	regulation of cellotriose transport	biological_process	Any process that modulates the frequency, rate or extent of cellotriose transport.
GO:1900286	negative regulation of cellotriose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.
GO:1900287	positive regulation of cellotriose transport	biological_process	Any process that activates or increases the frequency, rate or extent of cellotriose transport.
GO:1900288	regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	biological_process	Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
GO:1900289	negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
GO:1900290	positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
GO:1900291	regulation of galactotriose transport	biological_process	Any process that modulates the frequency, rate or extent of galactotriose transport.
GO:1900292	negative regulation of galactotriose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport.
GO:1900293	positive regulation of galactotriose transport	biological_process	Any process that activates or increases the frequency, rate or extent of galactotriose transport.
GO:1900294	regulation of heptasaccharide transport	biological_process	Any process that modulates the frequency, rate or extent of heptasaccharide transport.
GO:1900295	negative regulation of heptasaccharide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.
GO:1900296	positive regulation of heptasaccharide transport	biological_process	Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.
GO:1900297	regulation of hexasaccharide transport	biological_process	Any process that modulates the frequency, rate or extent of hexasaccharide transport.
GO:1900298	negative regulation of hexasaccharide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.
GO:1900299	positive regulation of hexasaccharide transport	biological_process	Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.
GO:1900303	regulation of laminaritriose transport	biological_process	Any process that modulates the frequency, rate or extent of laminaritriose transport.
GO:1900304	negative regulation of laminaritriose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport.
GO:1900305	positive regulation of laminaritriose transport	biological_process	Any process that activates or increases the frequency, rate or extent of laminaritriose transport.
GO:1900306	regulation of maltoheptaose transport	biological_process	Any process that modulates the frequency, rate or extent of maltoheptaose transport.
GO:1900307	negative regulation of maltoheptaose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport.
GO:1900308	positive regulation of maltoheptaose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.
GO:1900309	regulation of maltoheptaose metabolic process	biological_process	Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.
GO:1900310	negative regulation of maltoheptaose metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process.
GO:1900311	positive regulation of maltoheptaose metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process.
GO:1900312	regulation of maltohexaose transport	biological_process	Any process that modulates the frequency, rate or extent of maltohexaose transport.
GO:1900313	negative regulation of maltohexaose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.
GO:1900314	positive regulation of maltohexaose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltohexaose transport.
GO:1900315	regulation of maltopentaose transport	biological_process	Any process that modulates the frequency, rate or extent of maltopentaose transport.
GO:1900316	negative regulation of maltopentaose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport.
GO:1900317	positive regulation of maltopentaose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltopentaose transport.
GO:1900318	regulation of methane biosynthetic process from dimethylamine	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.
GO:1900319	negative regulation of methane biosynthetic process from dimethylamine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine.
GO:1900320	positive regulation of methane biosynthetic process from dimethylamine	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine.
GO:1900321	regulation of maltotetraose transport	biological_process	Any process that modulates the frequency, rate or extent of maltotetraose transport.
GO:1900322	negative regulation of maltotetraose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.
GO:1900323	positive regulation of maltotetraose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltotetraose transport.
GO:1900324	regulation of maltotriulose transport	biological_process	Any process that modulates the frequency, rate or extent of maltotriulose transport.
GO:1900325	negative regulation of maltotriulose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.
GO:1900326	positive regulation of maltotriulose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltotriulose transport.
GO:1900327	regulation of mannotriose transport	biological_process	Any process that modulates the frequency, rate or extent of mannotriose transport.
GO:1900328	negative regulation of mannotriose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.
GO:1900329	positive regulation of mannotriose transport	biological_process	Any process that activates or increases the frequency, rate or extent of mannotriose transport.
GO:1900330	regulation of methane biosynthetic process from trimethylamine	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine.
GO:1900331	negative regulation of methane biosynthetic process from trimethylamine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine.
GO:1900332	positive regulation of methane biosynthetic process from trimethylamine	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.
GO:1900333	regulation of methane biosynthetic process from 3-(methylthio)propionic acid	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
GO:1900334	negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
GO:1900335	positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
GO:1900336	regulation of methane biosynthetic process from carbon monoxide	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
GO:1900337	negative regulation of methane biosynthetic process from carbon monoxide	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
GO:1900338	positive regulation of methane biosynthetic process from carbon monoxide	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
GO:1900339	regulation of methane biosynthetic process from formic acid	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid.
GO:1900340	negative regulation of methane biosynthetic process from formic acid	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid.
GO:1900341	positive regulation of methane biosynthetic process from formic acid	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid.
GO:1900342	regulation of methane biosynthetic process from dimethyl sulfide	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
GO:1900343	negative regulation of methane biosynthetic process from dimethyl sulfide	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
GO:1900344	positive regulation of methane biosynthetic process from dimethyl sulfide	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
GO:1900345	regulation of methane biosynthetic process from methanethiol	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol.
GO:1900346	negative regulation of methane biosynthetic process from methanethiol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.
GO:1900347	positive regulation of methane biosynthetic process from methanethiol	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol.
GO:1900348	regulation of methane biosynthetic process from methylamine	biological_process	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.
GO:1900349	negative regulation of methane biosynthetic process from methylamine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine.
GO:1900350	positive regulation of methane biosynthetic process from methylamine	biological_process	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine.
GO:1900351	regulation of methanofuran biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.
GO:1900352	negative regulation of methanofuran biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process.
GO:1900353	positive regulation of methanofuran biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.
GO:1900354	regulation of methanofuran metabolic process	biological_process	Any process that modulates the frequency, rate or extent of methanofuran metabolic process.
GO:1900355	negative regulation of methanofuran metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.
GO:1900356	positive regulation of methanofuran metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.
GO:1900357	regulation of nigerotriose transport	biological_process	Any process that modulates the frequency, rate or extent of nigerotriose transport.
GO:1900358	negative regulation of nigerotriose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.
GO:1900359	positive regulation of nigerotriose transport	biological_process	Any process that activates or increases the frequency, rate or extent of nigerotriose transport.
GO:1900360	regulation of pentasaccharide transport	biological_process	Any process that modulates the frequency, rate or extent of pentasaccharide transport.
GO:1900361	negative regulation of pentasaccharide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport.
GO:1900362	positive regulation of pentasaccharide transport	biological_process	Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.
GO:1900364	negative regulation of mRNA polyadenylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.
GO:1900366	negative regulation of defense response to insect	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.
GO:1900367	positive regulation of defense response to insect	biological_process	Any process that activates or increases the frequency, rate or extent of defense response to insect.
GO:1900368	regulation of post-transcriptional gene silencing by regulatory ncRNA	biological_process	Any process that modulates the frequency, rate or extent of post-transcriptional gene silencing by a non-coding RNA.
GO:1900369	negative regulation of post-transcriptional gene silencing by regulatory ncRNA	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA.
GO:1900370	positive regulation of post-transcriptional gene silencing by RNA	biological_process	Any process that activates or increases the frequency, rate or extent of post-transcriptional gene silencing by RNA.
GO:1900371	regulation of purine nucleotide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.
GO:1900372	negative regulation of purine nucleotide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.
GO:1900373	positive regulation of purine nucleotide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.
GO:1900376	regulation of secondary metabolite biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.
GO:1900377	negative regulation of secondary metabolite biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.
GO:1900378	positive regulation of secondary metabolite biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
GO:1900379	regulation of asperthecin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process.
GO:1900380	negative regulation of asperthecin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process.
GO:1900381	positive regulation of asperthecin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process.
GO:1900383	regulation of synaptic plasticity by receptor localization to synapse	biological_process	Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse.
GO:1900384	regulation of flavonol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.
GO:1900385	negative regulation of flavonol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.
GO:1900386	positive regulation of flavonol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process.
GO:1900394	regulation of kojic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process.
GO:1900395	negative regulation of kojic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process.
GO:1900396	positive regulation of kojic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process.
GO:1900397	regulation of pyrimidine nucleotide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
GO:1900398	negative regulation of pyrimidine nucleotide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
GO:1900399	positive regulation of pyrimidine nucleotide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
GO:1900407	regulation of cellular response to oxidative stress	biological_process	Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.
GO:1900408	negative regulation of cellular response to oxidative stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.
GO:1900409	positive regulation of cellular response to oxidative stress	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.
GO:1900419	regulation of cellular alcohol catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process.
GO:1900420	negative regulation of cellular alcohol catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.
GO:1900421	positive regulation of cellular alcohol catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process.
GO:1900424	regulation of defense response to bacterium	biological_process	Any process that modulates the frequency, rate or extent of defense response to bacterium.
GO:1900425	negative regulation of defense response to bacterium	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.
GO:1900426	positive regulation of defense response to bacterium	biological_process	Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
GO:1900428	regulation of filamentous growth of a population of unicellular organisms	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
GO:1900429	negative regulation of filamentous growth of a population of unicellular organisms	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
GO:1900430	positive regulation of filamentous growth of a population of unicellular organisms	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
GO:1900431	regulation of filamentous growth of a population of unicellular organisms in response to heat	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
GO:1900432	negative regulation of filamentous growth of a population of unicellular organisms in response to heat	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
GO:1900433	positive regulation of filamentous growth of a population of unicellular organisms in response to heat	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
GO:1900434	regulation of filamentous growth of a population of unicellular organisms in response to starvation	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
GO:1900436	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
GO:1900437	regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
GO:1900438	negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
GO:1900439	positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
GO:1900440	regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
GO:1900441	negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
GO:1900442	positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
GO:1900443	regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
GO:1900444	negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
GO:1900445	positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
GO:1900447	regulation of cell morphogenesis involved in phenotypic switching	biological_process	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GO:1900449	regulation of glutamate receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.
GO:1900450	negative regulation of glutamate receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.
GO:1900451	positive regulation of glutamate receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.
GO:1900452	regulation of long-term synaptic depression	biological_process	Any process that modulates the frequency, rate or extent of long term synaptic depression.
GO:1900453	negative regulation of long-term synaptic depression	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.
GO:1900454	positive regulation of long-term synaptic depression	biological_process	Any process that activates or increases the frequency, rate or extent of long term synaptic depression.
GO:1900457	regulation of brassinosteroid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.
GO:1900458	negative regulation of brassinosteroid mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.
GO:1900459	positive regulation of brassinosteroid mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.
GO:1900461	positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter	biological_process	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:1900468	regulation of phosphatidylserine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process.
GO:1900469	negative regulation of phosphatidylserine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process.
GO:1900470	positive regulation of phosphatidylserine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process.
GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
GO:1900480	regulation of diacylglycerol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.
GO:1900481	negative regulation of diacylglycerol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process.
GO:1900482	positive regulation of diacylglycerol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.
GO:1900483	regulation of protein targeting to vacuolar membrane	biological_process	Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.
GO:1900484	negative regulation of protein targeting to vacuolar membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.
GO:1900485	positive regulation of protein targeting to vacuolar membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.
GO:1900486	positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	biological_process	Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
GO:1900487	regulation of [2Fe-2S] cluster assembly	biological_process	Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.
GO:1900488	negative regulation of [2Fe-2S] cluster assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.
GO:1900489	positive regulation of [2Fe-2S] cluster assembly	biological_process	Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly.
GO:1900491	regulation of [4Fe-4S] cluster assembly	biological_process	Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.
GO:1900492	negative regulation of [4Fe-4S] cluster assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.
GO:1900493	positive regulation of [4Fe-4S] cluster assembly	biological_process	Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly.
GO:1900494	regulation of butyryl-CoA biosynthetic process from acetyl-CoA	biological_process	Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
GO:1900495	negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
GO:1900496	positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA	biological_process	Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
GO:1900497	regulation of butyryl-CoA catabolic process to butanol	biological_process	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
GO:1900498	negative regulation of butyryl-CoA catabolic process to butanol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
GO:1900499	positive regulation of butyryl-CoA catabolic process to butanol	biological_process	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
GO:1900500	regulation of butyryl-CoA catabolic process to butyrate	biological_process	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
GO:1900501	negative regulation of butyryl-CoA catabolic process to butyrate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
GO:1900502	positive regulation of butyryl-CoA catabolic process to butyrate	biological_process	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
GO:1900503	regulation of cellulosome assembly	biological_process	Any process that modulates the frequency, rate or extent of cellulosome assembly.
GO:1900504	negative regulation of cellulosome assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly.
GO:1900505	positive regulation of cellulosome assembly	biological_process	Any process that activates or increases the frequency, rate or extent of cellulosome assembly.
GO:1900506	regulation of iron-sulfur-molybdenum cofactor assembly	biological_process	Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
GO:1900507	negative regulation of iron-sulfur-molybdenum cofactor assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
GO:1900508	positive regulation of iron-sulfur-molybdenum cofactor assembly	biological_process	Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
GO:1900509	regulation of pentose catabolic process to ethanol	biological_process	Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol.
GO:1900510	negative regulation of pentose catabolic process to ethanol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol.
GO:1900511	positive regulation of pentose catabolic process to ethanol	biological_process	Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol.
GO:1900512	regulation of starch utilization system complex assembly	biological_process	Any process that modulates the frequency, rate or extent of starch utilization system complex assembly.
GO:1900513	negative regulation of starch utilization system complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly.
GO:1900514	positive regulation of starch utilization system complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly.
GO:1900515	regulation of xylose catabolic process to ethanol	biological_process	Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol.
GO:1900516	negative regulation of xylose catabolic process to ethanol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol.
GO:1900517	positive regulation of xylose catabolic process to ethanol	biological_process	Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.
GO:1900518	regulation of response to pullulan	biological_process	Any process that modulates the frequency, rate or extent of response to pullulan.
GO:1900519	negative regulation of response to pullulan	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.
GO:1900520	positive regulation of response to pullulan	biological_process	Any process that activates or increases the frequency, rate or extent of response to pullulan.
GO:1900521	regulation of response to amylopectin	biological_process	Any process that modulates the frequency, rate or extent of response to amylopectin.
GO:1900522	negative regulation of response to amylopectin	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.
GO:1900523	positive regulation of response to amylopectin	biological_process	Any process that activates or increases the frequency, rate or extent of response to amylopectin.
GO:1900533	palmitic acid metabolic process	biological_process	The chemical reactions and pathways involving palmitic acid.
GO:1900534	palmitic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of palmitic acid.
GO:1900535	palmitic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of palmitic acid.
GO:1900539	fumonisin metabolic process	biological_process	The chemical reactions and pathways involving fumonisin.
GO:1900540	fumonisin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fumonisin.
GO:1900541	fumonisin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fumonisin.
GO:1900542	regulation of purine nucleotide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
GO:1900543	negative regulation of purine nucleotide metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
GO:1900544	positive regulation of purine nucleotide metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.
GO:1900548	heme B catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
GO:1900549	N',N'',N'''-triacetylfusarinine C metabolic process	biological_process	The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C.
GO:1900550	N',N'',N'''-triacetylfusarinine C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C.
GO:1900551	N',N'',N'''-triacetylfusarinine C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.
GO:1900552	asperfuranone metabolic process	biological_process	The chemical reactions and pathways involving asperfuranone.
GO:1900553	asperfuranone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of asperfuranone.
GO:1900554	asperfuranone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of asperfuranone.
GO:1900555	emericellamide metabolic process	biological_process	The chemical reactions and pathways involving emericellamide.
GO:1900556	emericellamide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of emericellamide.
GO:1900557	emericellamide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of emericellamide.
GO:1900558	austinol metabolic process	biological_process	The chemical reactions and pathways involving austinol.
GO:1900559	austinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of austinol.
GO:1900560	austinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of austinol.
GO:1900561	dehydroaustinol metabolic process	biological_process	The chemical reactions and pathways involving dehydroaustinol.
GO:1900562	dehydroaustinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.
GO:1900563	dehydroaustinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of dehydroaustinol.
GO:1900564	chanoclavine-I metabolic process	biological_process	The chemical reactions and pathways involving chanoclavine-I.
GO:1900567	chanoclavine-I aldehyde metabolic process	biological_process	The chemical reactions and pathways involving chanoclavine-I aldehyde.
GO:1900569	chanoclavine-I aldehyde biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine.
GO:1900570	diorcinol metabolic process	biological_process	The chemical reactions and pathways involving diorcinol.
GO:1900571	diorcinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diorcinol.
GO:1900572	diorcinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of diorcinol.
GO:1900573	emodin metabolic process	biological_process	The chemical reactions and pathways involving emodin.
GO:1900574	emodin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of emodin.
GO:1900575	emodin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of emodin.
GO:1900576	gerfelin metabolic process	biological_process	The chemical reactions and pathways involving gerfelin.
GO:1900577	gerfelin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gerfelin.
GO:1900578	gerfelin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gerfelin.
GO:1900579	(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process	biological_process	The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol.
GO:1900580	(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.
GO:1900581	(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.
GO:1900582	o-orsellinic acid metabolic process	biological_process	The chemical reactions and pathways involving o-orsellinic acid.
GO:1900583	o-orsellinic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.
GO:1900584	o-orsellinic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of o-orsellinic acid.
GO:1900585	arugosin metabolic process	biological_process	The chemical reactions and pathways involving arugosin.
GO:1900586	arugosin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of arugosin.
GO:1900587	arugosin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of arugosin.
GO:1900588	violaceol I metabolic process	biological_process	The chemical reactions and pathways involving violaceol I.
GO:1900589	violaceol I catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of violaceol I.
GO:1900590	violaceol I biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of violaceol I.
GO:1900591	violaceol II metabolic process	biological_process	The chemical reactions and pathways involving violaceol II.
GO:1900592	violaceol II catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of violaceol II.
GO:1900593	violaceol II biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of violaceol II.
GO:1900594	(+)-kotanin metabolic process	biological_process	The chemical reactions and pathways involving (+)-kotanin.
GO:1900595	(+)-kotanin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.
GO:1900596	(+)-kotanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-kotanin.
GO:1900597	demethylkotanin metabolic process	biological_process	The chemical reactions and pathways involving demethylkotanin.
GO:1900598	demethylkotanin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of demethylkotanin.
GO:1900599	demethylkotanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of demethylkotanin.
GO:1900600	endocrocin metabolic process	biological_process	The chemical reactions and pathways involving endocrocin.
GO:1900601	endocrocin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of endocrocin.
GO:1900602	endocrocin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of endocrocin.
GO:1900603	tensidol A metabolic process	biological_process	The chemical reactions and pathways involving tensidol A.
GO:1900604	tensidol A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tensidol A.
GO:1900605	tensidol A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tensidol A.
GO:1900606	tensidol B metabolic process	biological_process	The chemical reactions and pathways involving tensidol B.
GO:1900607	tensidol B catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tensidol B.
GO:1900608	tensidol B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tensidol B.
GO:1900609	F-9775A metabolic process	biological_process	The chemical reactions and pathways involving F-9775A.
GO:1900610	F-9775A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of F-9775A.
GO:1900611	F-9775A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of F-9775A.
GO:1900612	F-9775B metabolic process	biological_process	The chemical reactions and pathways involving F-9775B.
GO:1900613	F-9775B catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of F-9775B.
GO:1900614	F-9775B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of F-9775B.
GO:1900615	emericellamide A metabolic process	biological_process	The chemical reactions and pathways involving emericellamide A.
GO:1900616	emericellamide A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of emericellamide A.
GO:1900617	emericellamide A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of emericellamide A.
GO:1900618	regulation of shoot system morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of shoot morphogenesis.
GO:1900619	acetate ester metabolic process	biological_process	The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.
GO:1900620	acetate ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.
GO:1900623	regulation of monocyte aggregation	biological_process	Any process that modulates the frequency, rate or extent of monocyte aggregation.
GO:1900624	negative regulation of monocyte aggregation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.
GO:1900625	positive regulation of monocyte aggregation	biological_process	Any process that activates or increases the frequency, rate or extent of monocyte aggregation.
GO:1900626	regulation of arugosin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.
GO:1900627	negative regulation of arugosin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.
GO:1900628	positive regulation of arugosin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process.
GO:1900629	methanophenazine metabolic process	biological_process	The chemical reactions and pathways involving methanophenazine.
GO:1900630	methanophenazine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methanophenazine.
GO:1900631	tridecane metabolic process	biological_process	The chemical reactions and pathways involving tridecane.
GO:1900632	tridecane biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tridecane.
GO:1900633	pentadecane metabolic process	biological_process	The chemical reactions and pathways involving pentadecane.
GO:1900634	pentadecane biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pentadecane.
GO:1900635	heptadecane metabolic process	biological_process	The chemical reactions and pathways involving heptadecane.
GO:1900636	heptadecane biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heptadecane.
GO:1900637	regulation of asperfuranone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process.
GO:1900638	negative regulation of asperfuranone biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process.
GO:1900639	positive regulation of asperfuranone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process.
GO:1900640	regulation of austinol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of austinol biosynthetic process.
GO:1900641	negative regulation of austinol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.
GO:1900642	positive regulation of austinol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.
GO:1900646	regulation of chanoclavine-I aldehyde biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
GO:1900647	negative regulation of chanoclavine-I aldehyde biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
GO:1900648	positive regulation of chanoclavine-I aldehyde biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
GO:1900649	regulation of dehydroaustinol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.
GO:1900650	negative regulation of dehydroaustinol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.
GO:1900651	positive regulation of dehydroaustinol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process.
GO:1900652	regulation of demethylkotanin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.
GO:1900653	negative regulation of demethylkotanin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.
GO:1900654	positive regulation of demethylkotanin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process.
GO:1900655	regulation of diorcinol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process.
GO:1900656	negative regulation of diorcinol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process.
GO:1900657	positive regulation of diorcinol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process.
GO:1900658	regulation of emericellamide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process.
GO:1900659	negative regulation of emericellamide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process.
GO:1900660	positive regulation of emericellamide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process.
GO:1900661	regulation of emericellamide A biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process.
GO:1900662	negative regulation of emericellamide A biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process.
GO:1900663	positive regulation of emericellamide A biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process.
GO:1900664	regulation of emodin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of emodin biosynthetic process.
GO:1900665	negative regulation of emodin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.
GO:1900666	positive regulation of emodin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process.
GO:1900667	regulation of endocrocin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.
GO:1900668	negative regulation of endocrocin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process.
GO:1900669	positive regulation of endocrocin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process.
GO:1900670	regulation of F-9775A biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process.
GO:1900671	negative regulation of F-9775A biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process.
GO:1900672	positive regulation of F-9775A biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.
GO:1900673	olefin metabolic process	biological_process	The chemical reactions and pathways involving olefin.
GO:1900674	olefin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of olefin.
GO:1900675	regulation of F-9775B biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process.
GO:1900676	negative regulation of F-9775B biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process.
GO:1900677	positive regulation of F-9775B biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process.
GO:1900678	regulation of ferricrocin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.
GO:1900679	negative regulation of ferricrocin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process.
GO:1900680	positive regulation of ferricrocin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process.
GO:1900681	octadecene metabolic process	biological_process	The chemical reactions and pathways involving octadecene.
GO:1900682	octadecene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of octadecene.
GO:1900683	regulation of fumonisin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process.
GO:1900684	negative regulation of fumonisin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process.
GO:1900685	positive regulation of fumonisin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process.
GO:1900686	regulation of gerfelin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process.
GO:1900687	negative regulation of gerfelin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.
GO:1900688	positive regulation of gerfelin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process.
GO:1900689	regulation of gliotoxin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process.
GO:1900690	negative regulation of gliotoxin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process.
GO:1900691	positive regulation of gliotoxin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process.
GO:1900692	regulation of (+)-kotanin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.
GO:1900693	negative regulation of (+)-kotanin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.
GO:1900694	positive regulation of (+)-kotanin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.
GO:1900695	regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
GO:1900696	negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
GO:1900697	positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
GO:1900698	regulation of o-orsellinic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process.
GO:1900699	negative regulation of o-orsellinic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process.
GO:1900700	positive regulation of o-orsellinic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process.
GO:1900701	regulation of orcinol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.
GO:1900702	negative regulation of orcinol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.
GO:1900703	positive regulation of orcinol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process.
GO:1900704	regulation of siderophore biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of siderophore biosynthetic process.
GO:1900705	negative regulation of siderophore biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process.
GO:1900706	positive regulation of siderophore biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process.
GO:1900707	regulation of tensidol A biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process.
GO:1900708	negative regulation of tensidol A biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process.
GO:1900709	positive regulation of tensidol A biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process.
GO:1900710	regulation of tensidol B biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process.
GO:1900711	negative regulation of tensidol B biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process.
GO:1900712	positive regulation of tensidol B biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process.
GO:1900713	regulation of violaceol I biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.
GO:1900714	negative regulation of violaceol I biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.
GO:1900715	positive regulation of violaceol I biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process.
GO:1900716	regulation of violaceol II biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.
GO:1900717	negative regulation of violaceol II biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.
GO:1900718	positive regulation of violaceol II biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process.
GO:1900719	regulation of uterine smooth muscle relaxation	biological_process	Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.
GO:1900720	negative regulation of uterine smooth muscle relaxation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.
GO:1900721	positive regulation of uterine smooth muscle relaxation	biological_process	Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.
GO:1900722	regulation of protein adenylylation	biological_process	Any process that modulates the frequency, rate or extent of protein adenylylation.
GO:1900723	negative regulation of protein adenylylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.
GO:1900724	positive regulation of protein adenylylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein adenylylation.
GO:1900725	osmoregulated periplasmic glucan metabolic process	biological_process	The chemical reactions and pathways involving osmoregulated periplasmic glucan.
GO:1900726	osmoregulated periplasmic glucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.
GO:1900727	osmoregulated periplasmic glucan biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.
GO:1900728	cardiac neural crest cell delamination involved in outflow tract morphogenesis	biological_process	Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis.
GO:1900729	regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
GO:1900730	negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
GO:1900731	positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
GO:1900732	regulation of polyketide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of polyketide biosynthetic process.
GO:1900733	negative regulation of polyketide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process.
GO:1900734	positive regulation of polyketide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process.
GO:1900735	positive regulation of flocculation	biological_process	Any process that activates or increases the frequency, rate or extent of flocculation.
GO:1900736	regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.
GO:1900737	negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.
GO:1900738	positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.
GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.
GO:1900741	regulation of filamentous growth of a population of unicellular organisms in response to pH	biological_process	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
GO:1900742	negative regulation of filamentous growth of a population of unicellular organisms in response to pH	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
GO:1900743	positive regulation of filamentous growth of a population of unicellular organisms in response to pH	biological_process	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
GO:1900744	regulation of p38MAPK cascade	biological_process	Any process that modulates the frequency, rate or extent of p38MAPK cascade.
GO:1900745	positive regulation of p38MAPK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
GO:1900749	(R)-carnitine transport	biological_process	The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900750	oligopeptide binding	molecular_function	Binding to an oligopeptide.
GO:1900751	4-(trimethylammonio)butanoate transport	biological_process	The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900752	malonic acid transport	biological_process	The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900753	doxorubicin transport	biological_process	The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900754	4-hydroxyphenylacetate transport	biological_process	The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900756	protein processing in phagocytic vesicle	biological_process	Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation.
GO:1900757	regulation of D-amino-acid oxidase activity	biological_process	Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity.
GO:1900758	negative regulation of D-amino-acid oxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity.
GO:1900759	positive regulation of D-amino-acid oxidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity.
GO:1900760	negative regulation of sterigmatocystin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.
GO:1900761	averantin metabolic process	biological_process	The chemical reactions and pathways involving averantin.
GO:1900762	averantin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of averantin.
GO:1900763	averantin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of averantin.
GO:1900764	emericellin metabolic process	biological_process	The chemical reactions and pathways involving emericellin.
GO:1900765	emericellin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of emericellin.
GO:1900766	emericellin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of emericellin.
GO:1900767	fonsecin metabolic process	biological_process	The chemical reactions and pathways involving fonsecin.
GO:1900768	fonsecin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fonsecin.
GO:1900769	fonsecin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fonsecin.
GO:1900772	fumitremorgin B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the indole alkaloid fumitremorgin B.
GO:1900781	fumiquinazoline C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C.
GO:1900785	naphtho-gamma-pyrone metabolic process	biological_process	The chemical reactions and pathways involving naphtho-gamma-pyrone.
GO:1900786	naphtho-gamma-pyrone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone.
GO:1900787	naphtho-gamma-pyrone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.
GO:1900788	pseurotin A metabolic process	biological_process	The chemical reactions and pathways involving pseurotin A.
GO:1900789	pseurotin A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pseurotin A.
GO:1900790	pseurotin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pseurotin A.
GO:1900791	shamixanthone metabolic process	biological_process	The chemical reactions and pathways involving shamixanthone.
GO:1900792	shamixanthone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of shamixanthone.
GO:1900793	shamixanthone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of shamixanthone.
GO:1900796	terrequinone A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of terrequinone A.
GO:1900797	cordyol C metabolic process	biological_process	The chemical reactions and pathways involving cordyol C.
GO:1900798	cordyol C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cordyol C.
GO:1900799	cordyol C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cordyol C.
GO:1900800	cspyrone B1 metabolic process	biological_process	The chemical reactions and pathways involving cspyrone B1.
GO:1900801	cspyrone B1 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cspyrone B1.
GO:1900802	cspyrone B1 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cspyrone B1.
GO:1900805	brevianamide F biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of brevianamide F. Brevianamide F is the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by some fungi.
GO:1900809	fumigaclavine C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fumigaclavine C, a fungal ergot alkaloid.
GO:1900810	helvolic acid metabolic process	biological_process	The chemical reactions and pathways involving helvolic acid.
GO:1900811	helvolic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of helvolic acid.
GO:1900812	helvolic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of helvolic acid.
GO:1900813	monodictyphenone metabolic process	biological_process	The chemical reactions and pathways involving monodictyphenone.
GO:1900814	monodictyphenone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monodictyphenone.
GO:1900815	monodictyphenone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monodictyphenone.
GO:1900816	ochratoxin A metabolic process	biological_process	The chemical reactions and pathways involving ochratoxin A.
GO:1900817	ochratoxin A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ochratoxin A.
GO:1900818	ochratoxin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ochratoxin A.
GO:1900819	orlandin metabolic process	biological_process	The chemical reactions and pathways involving orlandin.
GO:1900820	orlandin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of orlandin.
GO:1900821	orlandin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of orlandin.
GO:1900822	regulation of ergot alkaloid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.
GO:1900823	negative regulation of ergot alkaloid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.
GO:1900824	positive regulation of ergot alkaloid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process.
GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
GO:1900826	negative regulation of membrane depolarization during cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
GO:1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
GO:1900828	D-tyrosine metabolic process	biological_process	The chemical reactions and pathways involving D-tyrosine.
GO:1900829	D-tyrosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-tyrosine.
GO:1900831	D-leucine metabolic process	biological_process	The chemical reactions and pathways involving D-leucine.
GO:1900832	D-leucine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-leucine.
GO:1900833	D-leucine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-leucine.
GO:1900834	regulation of emericellin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.
GO:1900835	negative regulation of emericellin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process.
GO:1900836	positive regulation of emericellin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.
GO:1900837	regulation of fumigaclavine C biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.
GO:1900838	negative regulation of fumigaclavine C biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process.
GO:1900839	positive regulation of fumigaclavine C biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process.
GO:1900840	regulation of helvolic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process.
GO:1900841	negative regulation of helvolic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.
GO:1900842	positive regulation of helvolic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.
GO:1900843	regulation of monodictyphenone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process.
GO:1900844	negative regulation of monodictyphenone biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process.
GO:1900845	positive regulation of monodictyphenone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process.
GO:1900846	regulation of naphtho-gamma-pyrone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
GO:1900847	negative regulation of naphtho-gamma-pyrone biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
GO:1900848	positive regulation of naphtho-gamma-pyrone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
GO:1900849	regulation of pseurotin A biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.
GO:1900850	negative regulation of pseurotin A biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.
GO:1900851	positive regulation of pseurotin A biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process.
GO:1900854	positive regulation of terrequinone A biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process.
GO:1900861	regulation of cordyol C biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process.
GO:1900862	negative regulation of cordyol C biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.
GO:1900863	positive regulation of cordyol C biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process.
GO:1900864	mitochondrial RNA modification	biological_process	Any RNA modification that takes place in mitochondrion.
GO:1900865	chloroplast RNA modification	biological_process	Any RNA modification that takes place in chloroplast.
GO:1900866	glycolate transport	biological_process	The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1900867	sarcinapterin metabolic process	biological_process	The chemical reactions and pathways involving sarcinapterin.
GO:1900868	sarcinapterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sarcinapterin.
GO:1900869	tatiopterin metabolic process	biological_process	The chemical reactions and pathways involving tatiopterin.
GO:1900870	tatiopterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tatiopterin.
GO:1900871	chloroplast mRNA modification	biological_process	The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.
GO:1900872	pentadec-1-ene metabolic process	biological_process	The chemical reactions and pathways involving pentadec-1-ene.
GO:1900873	pentadec-1-ene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pentadec-1-ene.
GO:1900874	heptadec-1-ene metabolic process	biological_process	The chemical reactions and pathways involving heptadec-1-ene.
GO:1900875	heptadec-1-ene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of heptadec-1-ene.
GO:1900876	nonadec-1-ene metabolic process	biological_process	The chemical reactions and pathways involving nonadec-1-ene.
GO:1900877	nonadec-1-ene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nonadec-1-ene.
GO:1900878	(Z)-nonadeca-1,14-diene metabolic process	biological_process	The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene.
GO:1900879	(Z)-nonadeca-1,14-diene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene.
GO:1900880	18-methylnonadec-1-ene metabolic process	biological_process	The chemical reactions and pathways involving 18-methylnonadec-1-ene.
GO:1900881	18-methylnonadec-1-ene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene.
GO:1900882	17-methylnonadec-1-ene metabolic process	biological_process	The chemical reactions and pathways involving 17-methylnonadec-1-ene.
GO:1900883	17-methylnonadec-1-ene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene.
GO:1900884	regulation of tridecane biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.
GO:1900885	negative regulation of tridecane biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.
GO:1900886	positive regulation of tridecane biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process.
GO:1900887	regulation of pentadecane biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.
GO:1900888	negative regulation of pentadecane biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.
GO:1900889	positive regulation of pentadecane biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process.
GO:1900890	regulation of pentadecane metabolic process	biological_process	Any process that modulates the frequency, rate or extent of pentadecane metabolic process.
GO:1900891	negative regulation of pentadecane metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process.
GO:1900892	positive regulation of pentadecane metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.
GO:1900893	regulation of tridecane metabolic process	biological_process	Any process that modulates the frequency, rate or extent of tridecane metabolic process.
GO:1900894	negative regulation of tridecane metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process.
GO:1900895	positive regulation of tridecane metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tridecane metabolic process.
GO:1900896	regulation of heptadecane biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.
GO:1900897	negative regulation of heptadecane biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.
GO:1900898	positive regulation of heptadecane biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.
GO:1900899	regulation of heptadecane metabolic process	biological_process	Any process that modulates the frequency, rate or extent of heptadecane metabolic process.
GO:1900900	negative regulation of heptadecane metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process.
GO:1900901	positive regulation of heptadecane metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process.
GO:1900902	regulation of hexadecanal biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.
GO:1900903	negative regulation of hexadecanal biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.
GO:1900904	positive regulation of hexadecanal biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.
GO:1900905	regulation of hexadecanal metabolic process	biological_process	Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.
GO:1900906	negative regulation of hexadecanal metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process.
GO:1900907	positive regulation of hexadecanal metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process.
GO:1900908	regulation of olefin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of olefin metabolic process.
GO:1900909	negative regulation of olefin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process.
GO:1900910	positive regulation of olefin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of olefin metabolic process.
GO:1900911	regulation of olefin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of olefin biosynthetic process.
GO:1900912	negative regulation of olefin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process.
GO:1900913	positive regulation of olefin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.
GO:1900914	regulation of octadecene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of octadecene biosynthetic process.
GO:1900915	negative regulation of octadecene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process.
GO:1900916	positive regulation of octadecene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process.
GO:1900917	regulation of octadecene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of octadecene metabolic process.
GO:1900918	negative regulation of octadecene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process.
GO:1900919	positive regulation of octadecene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of octadecene metabolic process.
GO:1900923	regulation of glycine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of glycine import into a cell.
GO:1900924	negative regulation of glycine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.
GO:1900925	positive regulation of glycine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of glycine import.
GO:1900926	regulation of L-threonine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-threonine import into cell.
GO:1900927	negative regulation of L-threonine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell.
GO:1900928	positive regulation of L-threonine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-threonine import into cell.
GO:1900929	regulation of L-tyrosine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.
GO:1900930	negative regulation of L-tyrosine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.
GO:1900931	positive regulation of L-tyrosine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.
GO:1900932	regulation of nonadec-1-ene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.
GO:1900933	negative regulation of nonadec-1-ene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process.
GO:1900934	positive regulation of nonadec-1-ene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process.
GO:1900935	regulation of nonadec-1-ene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process.
GO:1900936	negative regulation of nonadec-1-ene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process.
GO:1900937	positive regulation of nonadec-1-ene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process.
GO:1900938	regulation of (Z)-nonadeca-1,14-diene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
GO:1900939	negative regulation of (Z)-nonadeca-1,14-diene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
GO:1900940	positive regulation of (Z)-nonadeca-1,14-diene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
GO:1900941	regulation of (Z)-nonadeca-1,14-diene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
GO:1900942	negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
GO:1900943	positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
GO:1900944	regulation of isoprene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of isoprene metabolic process.
GO:1900945	negative regulation of isoprene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process.
GO:1900946	positive regulation of isoprene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of isoprene metabolic process.
GO:1900947	regulation of isoprene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of isoprene biosynthetic process.
GO:1900948	negative regulation of isoprene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process.
GO:1900949	positive regulation of isoprene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process.
GO:1900950	regulation of 18-methylnonadec-1-ene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
GO:1900951	negative regulation of 18-methylnonadec-1-ene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
GO:1900952	positive regulation of 18-methylnonadec-1-ene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
GO:1900953	regulation of 18-methylnonadec-1-ene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
GO:1900954	negative regulation of 18-methylnonadec-1-ene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
GO:1900955	positive regulation of 18-methylnonadec-1-ene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
GO:1900956	regulation of 17-methylnonadec-1-ene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
GO:1900957	negative regulation of 17-methylnonadec-1-ene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
GO:1900958	positive regulation of 17-methylnonadec-1-ene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
GO:1900959	regulation of 17-methylnonadec-1-ene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
GO:1900960	negative regulation of 17-methylnonadec-1-ene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
GO:1900961	positive regulation of 17-methylnonadec-1-ene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
GO:1900962	regulation of methanophenazine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.
GO:1900963	negative regulation of methanophenazine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process.
GO:1900964	positive regulation of methanophenazine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.
GO:1900965	regulation of methanophenazine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.
GO:1900966	negative regulation of methanophenazine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.
GO:1900967	positive regulation of methanophenazine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process.
GO:1900968	regulation of sarcinapterin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process.
GO:1900969	negative regulation of sarcinapterin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.
GO:1900970	positive regulation of sarcinapterin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process.
GO:1900971	regulation of sarcinapterin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.
GO:1900972	negative regulation of sarcinapterin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.
GO:1900973	positive regulation of sarcinapterin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process.
GO:1900974	regulation of tatiopterin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.
GO:1900975	negative regulation of tatiopterin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.
GO:1900976	positive regulation of tatiopterin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.
GO:1900977	regulation of tatiopterin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of tatiopterin metabolic process.
GO:1900978	negative regulation of tatiopterin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process.
GO:1900979	positive regulation of tatiopterin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process.
GO:1900980	regulation of phenazine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.
GO:1900981	negative regulation of phenazine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.
GO:1900982	positive regulation of phenazine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process.
GO:1900983	vindoline metabolic process	biological_process	The chemical reactions and pathways involving vindoline.
GO:1900985	vindoline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vindoline.
GO:1900988	ajmaline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ajmaline.
GO:1900991	scopolamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of scopolamine.
GO:1900992	(-)-secologanin metabolic process	biological_process	The chemical reactions and pathways involving (-)-secologanin.
GO:1900993	(-)-secologanin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-secologanin.
GO:1900994	(-)-secologanin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-secologanin.
GO:1900995	ubiquinone-6 binding	molecular_function	Binding to ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.
GO:1900996	benzene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of benzene.
GO:1900997	benzene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of benzene.
GO:1900998	nitrobenzene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nitrobenzene.
GO:1900999	nitrobenzene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nitrobenzene.
GO:1901000	regulation of response to salt stress	biological_process	Any process that modulates the frequency, rate or extent of response to salt stress.
GO:1901001	negative regulation of response to salt stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.
GO:1901002	positive regulation of response to salt stress	biological_process	Any process that activates or increases the frequency, rate or extent of response to salt stress.
GO:1901003	negative regulation of fermentation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.
GO:1901004	ubiquinone-6 metabolic process	biological_process	The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.
GO:1901005	ubiquinone-6 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ubiquinone-6.
GO:1901006	ubiquinone-6 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ubiquinone-6.
GO:1901007	(S)-scoulerine metabolic process	biological_process	The chemical reactions and pathways involving (S)-scoulerine.
GO:1901009	(S)-scoulerine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (S)-scoulerine.
GO:1901010	(S)-reticuline metabolic process	biological_process	The chemical reactions and pathways involving (S)-reticuline.
GO:1901012	(S)-reticuline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (S)-reticuline.
GO:1901015	3alpha(S)-strictosidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine.
GO:1901016	regulation of potassium ion transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.
GO:1901019	regulation of calcium ion transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.
GO:1901022	4-hydroxyphenylacetate metabolic process	biological_process	The chemical reactions and pathways involving 4-hydroxyphenylacetate.
GO:1901023	4-hydroxyphenylacetate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.
GO:1901024	4-hydroxyphenylacetate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate.
GO:1901025	ripoptosome assembly involved in extrinsic apoptotic signaling pathway	biological_process	The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway.
GO:1901026	ripoptosome assembly involved in necroptotic process	biological_process	The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.
GO:1901027	dextrin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of dextrin.
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
GO:1901031	regulation of response to reactive oxygen species	biological_process	Any process that modulates the frequency, rate or extent of response to reactive oxygen species.
GO:1901032	negative regulation of response to reactive oxygen species	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.
GO:1901033	positive regulation of response to reactive oxygen species	biological_process	Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species.
GO:1901034	regulation of L-glutamine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-glutamine import into cell.
GO:1901035	negative regulation of L-glutamine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell.
GO:1901036	positive regulation of L-glutamine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell.
GO:1901038	cyanidin 3-O-glucoside metabolic process	biological_process	The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.
GO:1901039	regulation of peptide antigen transport	biological_process	Any process that modulates the frequency, rate or extent of peptide antigen transport.
GO:1901040	negative regulation of peptide antigen transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport.
GO:1901041	positive regulation of peptide antigen transport	biological_process	Any process that activates or increases the frequency, rate or extent of peptide antigen transport.
GO:1901045	negative regulation of egg-laying behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.
GO:1901046	positive regulation of egg-laying behavior	biological_process	Any process that activates or increases the frequency, rate or extent of oviposition.
GO:1901051	atropine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of atropine. Atropine is the racemic mixture of hyoscyamine.
GO:1901052	sarcosine metabolic process	biological_process	The chemical reactions and pathways involving sarcosine.
GO:1901053	sarcosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of sarcosine.
GO:1901054	sarcosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sarcosine.
GO:1901055	trimethylenediamine metabolic process	biological_process	The chemical reactions and pathways involving trimethylenediamine.
GO:1901056	trimethylenediamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.
GO:1901057	trimethylenediamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of trimethylenediamine.
GO:1901058	p-hydroxyphenyl lignin metabolic process	biological_process	The chemical reactions and pathways involving p-hydroxyphenyl lignin.
GO:1901059	p-hydroxyphenyl lignin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.
GO:1901060	p-hydroxyphenyl lignin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin.
GO:1901061	guaiacyl lignin metabolic process	biological_process	The chemical reactions and pathways involving guaiacyl lignin.
GO:1901062	guaiacyl lignin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.
GO:1901063	guaiacyl lignin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guaiacyl lignin.
GO:1901064	syringal lignin metabolic process	biological_process	The chemical reactions and pathways involving syringal lignin.
GO:1901065	syringal lignin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of syringal lignin.
GO:1901066	syringal lignin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of syringal lignin.
GO:1901067	ferulate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ferulate.
GO:1901068	guanosine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving guanosine-containing compounds (guanosines).
GO:1901069	guanosine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).
GO:1901070	guanosine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines).
GO:1901071	glucosamine-containing compound metabolic process	biological_process	The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines).
GO:1901072	glucosamine-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).
GO:1901073	glucosamine-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).
GO:1901074	regulation of engulfment of apoptotic cell	biological_process	Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.
GO:1901075	negative regulation of engulfment of apoptotic cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.
GO:1901076	positive regulation of engulfment of apoptotic cell	biological_process	Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.
GO:1901077	regulation of relaxation of muscle	biological_process	Any process that modulates the frequency, rate or extent of relaxation of muscle.
GO:1901078	negative regulation of relaxation of muscle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.
GO:1901079	positive regulation of relaxation of muscle	biological_process	Any process that activates or increases the frequency, rate or extent of relaxation of muscle.
GO:1901080	regulation of relaxation of smooth muscle	biological_process	Any process that modulates the frequency, rate or extent of relaxation of smooth muscle.
GO:1901081	negative regulation of relaxation of smooth muscle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.
GO:1901082	positive regulation of relaxation of smooth muscle	biological_process	Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.
GO:1901083	pyrrolizidine alkaloid metabolic process	biological_process	The chemical reactions and pathways involving pyrrolizidine alkaloid.
GO:1901085	pyrrolizidine alkaloid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid.
GO:1901086	benzylpenicillin metabolic process	biological_process	The chemical reactions and pathways involving benzylpenicillin.
GO:1901087	benzylpenicillin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.
GO:1901088	benzylpenicillin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of benzylpenicillin.
GO:1901089	acetate ester metabolic process involved in fermentation	biological_process	Any acetate ester metabolic process that is involved in fermentation.
GO:1901090	regulation of protein tetramerization	biological_process	Any process that modulates the frequency, rate or extent of protein tetramerization.
GO:1901091	negative regulation of protein tetramerization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization.
GO:1901092	positive regulation of protein tetramerization	biological_process	Any process that activates or increases the frequency, rate or extent of protein tetramerization.
GO:1901093	regulation of protein homotetramerization	biological_process	Any process that modulates the frequency, rate or extent of protein homotetramerization.
GO:1901094	negative regulation of protein homotetramerization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.
GO:1901095	positive regulation of protein homotetramerization	biological_process	Any process that activates or increases the frequency, rate or extent of protein homotetramerization.
GO:1901096	regulation of autophagosome maturation	biological_process	Any process that modulates the frequency, rate or extent of autophagosome maturation.
GO:1901097	negative regulation of autophagosome maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.
GO:1901098	positive regulation of autophagosome maturation	biological_process	Any process that activates or increases the frequency, rate or extent of autophagosome maturation.
GO:1901099	negative regulation of signal transduction in absence of ligand	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.
GO:1901101	gramicidin S metabolic process	biological_process	The chemical reactions and pathways involving gramicidin S.
GO:1901102	gramicidin S catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gramicidin S.
GO:1901103	gramicidin S biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gramicidin S.
GO:1901104	tetracenomycin C metabolic process	biological_process	The chemical reactions and pathways involving tetracenomycin C.
GO:1901105	tetracenomycin C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tetracenomycin C.
GO:1901106	tetracenomycin C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tetracenomycin C.
GO:1901107	granaticin metabolic process	biological_process	The chemical reactions and pathways involving granaticin.
GO:1901108	granaticin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of granaticin.
GO:1901109	granaticin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of granaticin.
GO:1901110	actinorhodin metabolic process	biological_process	The chemical reactions and pathways involving actinorhodin.
GO:1901111	actinorhodin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of actinorhodin.
GO:1901112	actinorhodin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of actinorhodin.
GO:1901113	erythromycin metabolic process	biological_process	The chemical reactions and pathways involving erythromycin.
GO:1901114	erythromycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of erythromycin.
GO:1901115	erythromycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of erythromycin.
GO:1901116	cephamycin C metabolic process	biological_process	The chemical reactions and pathways involving cephamycin C.
GO:1901117	cephamycin C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cephamycin C.
GO:1901118	cephamycin C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cephamycin C.
GO:1901119	tobramycin metabolic process	biological_process	The chemical reactions and pathways involving tobramycin.
GO:1901120	tobramycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tobramycin.
GO:1901121	tobramycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tobramycin.
GO:1901122	bacitracin A metabolic process	biological_process	The chemical reactions and pathways involving bacitracin A.
GO:1901123	bacitracin A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of bacitracin A.
GO:1901124	bacitracin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of bacitracin A.
GO:1901125	candicidin metabolic process	biological_process	The chemical reactions and pathways involving candicidin.
GO:1901126	candicidin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of candicidin.
GO:1901127	candicidin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of candicidin.
GO:1901128	gentamycin metabolic process	biological_process	The chemical reactions and pathways involving gentamycin.
GO:1901129	gentamycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of gentamycin.
GO:1901130	gentamycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of gentamycin.
GO:1901131	kanamycin metabolic process	biological_process	The chemical reactions and pathways involving kanamycin.
GO:1901132	kanamycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of kanamycin.
GO:1901133	kanamycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of kanamycin.
GO:1901135	carbohydrate derivative metabolic process	biological_process	The chemical reactions and pathways involving carbohydrate derivative.
GO:1901136	carbohydrate derivative catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.
GO:1901137	carbohydrate derivative biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GO:1901140	p-coumaryl alcohol transport	biological_process	The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901141	regulation of lignin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of lignin biosynthetic process.
GO:1901142	insulin metabolic process	biological_process	The chemical reactions and pathways involving insulin.
GO:1901143	insulin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of insulin.
GO:1901145	mesenchymal cell apoptotic process involved in nephron morphogenesis	biological_process	Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.
GO:1901146	mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	biological_process	Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis.
GO:1901147	mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	biological_process	Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.
GO:1901148	gene expression involved in extracellular matrix organization	biological_process	Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
GO:1901149	salicylic acid binding	molecular_function	Binding to salicylic acid.
GO:1901150	vistamycin metabolic process	biological_process	The chemical reactions and pathways involving vistamycin.
GO:1901151	vistamycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of vistamycin.
GO:1901152	vistamycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vistamycin.
GO:1901153	paromomycin metabolic process	biological_process	The chemical reactions and pathways involving paromomycin.
GO:1901154	paromomycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of paromomycin.
GO:1901155	paromomycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of paromomycin.
GO:1901156	neomycin metabolic process	biological_process	The chemical reactions and pathways involving neomycin.
GO:1901157	neomycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of neomycin.
GO:1901158	neomycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of neomycin.
GO:1901159	xylulose 5-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate.
GO:1901160	primary amino compound metabolic process	biological_process	The chemical reactions and pathways involving primary amino compound.
GO:1901161	primary amino compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of primary amino compound.
GO:1901162	primary amino compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of primary amino compound.
GO:1901163	regulation of trophoblast cell migration	biological_process	Any process that modulates the frequency, rate or extent of trophoblast cell migration.
GO:1901164	negative regulation of trophoblast cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.
GO:1901165	positive regulation of trophoblast cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.
GO:1901166	neural crest cell migration involved in autonomic nervous system development	biological_process	Any neural crest cell migration that is involved in autonomic nervous system development.
GO:1901167	3-chlorocatechol metabolic process	biological_process	The chemical reactions and pathways involving 3-chlorocatechol.
GO:1901168	3-chlorocatechol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.
GO:1901169	3-chlorocatechol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.
GO:1901170	naphthalene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of naphthalene.
GO:1901172	phytoene metabolic process	biological_process	The chemical reactions and pathways involving phytoene.
GO:1901173	phytoene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phytoene.
GO:1901174	phytoene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phytoene.
GO:1901175	lycopene metabolic process	biological_process	The chemical reactions and pathways involving lycopene.
GO:1901176	lycopene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lycopene.
GO:1901177	lycopene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lycopene.
GO:1901178	spheroidene metabolic process	biological_process	The chemical reactions and pathways involving spheroidene.
GO:1901179	spheroidene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of spheroidene.
GO:1901180	spheroidene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of spheroidene.
GO:1901181	negative regulation of cellular response to caffeine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.
GO:1901182	regulation of camalexin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of camalexin biosynthetic process.
GO:1901183	positive regulation of camalexin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.
GO:1901184	regulation of ERBB signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of ERBB signaling pathway.
GO:1901185	negative regulation of ERBB signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.
GO:1901186	positive regulation of ERBB signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.
GO:1901187	regulation of ephrin receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.
GO:1901188	negative regulation of ephrin receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway.
GO:1901189	positive regulation of ephrin receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.
GO:1901190	regulation of formation of translation initiation ternary complex	biological_process	Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.
GO:1901191	negative regulation of formation of translation initiation ternary complex	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.
GO:1901192	positive regulation of formation of translation initiation ternary complex	biological_process	Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.
GO:1901193	regulation of formation of translation preinitiation complex	biological_process	Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex.
GO:1901194	negative regulation of formation of translation preinitiation complex	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.
GO:1901195	positive regulation of formation of translation preinitiation complex	biological_process	Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.
GO:1901196	positive regulation of calcium-mediated signaling involved in cellular response to salt stress	biological_process	Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress.
GO:1901197	positive regulation of calcium-mediated signaling involved in cellular response to calcium ion	biological_process	Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.
GO:1901198	positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion	biological_process	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.
GO:1901199	positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress	biological_process	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.
GO:1901200	negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress	biological_process	Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.
GO:1901201	regulation of extracellular matrix assembly	biological_process	Any process that modulates the frequency, rate or extent of extracellular matrix assembly.
GO:1901202	negative regulation of extracellular matrix assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.
GO:1901203	positive regulation of extracellular matrix assembly	biological_process	Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.
GO:1901207	regulation of heart looping	biological_process	Any process that modulates the frequency, rate or extent of heart looping.
GO:1901208	negative regulation of heart looping	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.
GO:1901209	positive regulation of heart looping	biological_process	Any process that activates or increases the frequency, rate or extent of heart looping.
GO:1901210	regulation of cardiac chamber formation	biological_process	Any process that modulates the frequency, rate or extent of cardiac chamber formation.
GO:1901211	negative regulation of cardiac chamber formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.
GO:1901212	positive regulation of cardiac chamber formation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.
GO:1901219	regulation of cardiac chamber morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.
GO:1901220	negative regulation of cardiac chamber morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.
GO:1901221	positive regulation of cardiac chamber morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.
GO:1901222	regulation of non-canonical NF-kappaB signal transduction	biological_process	Any process that modulates the frequency, rate or extent of the non-canonical NF-kappaB signaling cascade.
GO:1901223	negative regulation of non-canonical NF-kappaB signal transduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical NF-kappaB signaling cascade.
GO:1901224	positive regulation of non-canonical NF-kappaB signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade.
GO:1901229	regulation of non-canonical Wnt signaling pathway via JNK cascade	biological_process	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
GO:1901230	negative regulation of non-canonical Wnt signaling pathway via JNK cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
GO:1901231	positive regulation of non-canonical Wnt signaling pathway via JNK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
GO:1901232	regulation of convergent extension involved in axis elongation	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.
GO:1901233	negative regulation of convergent extension involved in axis elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation.
GO:1901234	positive regulation of convergent extension involved in axis elongation	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation.
GO:1901235	(R)-carnitine transmembrane transporter activity	molecular_function	Enables the transfer of (R)-carnitine from one side of a membrane to the other.
GO:1901236	4-(trimethylammonio)butanoate transmembrane transporter activity	molecular_function	Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other.
GO:1901238	ABC-type tungstate transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).
GO:1901239	malonate(1-) transmembrane transporter activity	molecular_function	Enables the transfer of malonate(1-) from one side of a membrane to the other.
GO:1901241	4-hydroxyphenylacetate transmembrane transporter activity	molecular_function	Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.
GO:1901242	ABC-type doxorubicin transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).
GO:1901245	positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization	biological_process	The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling.
GO:1901246	regulation of lung ciliated cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.
GO:1901247	negative regulation of lung ciliated cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.
GO:1901248	positive regulation of lung ciliated cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.
GO:1901249	regulation of lung goblet cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.
GO:1901250	negative regulation of lung goblet cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.
GO:1901251	positive regulation of lung goblet cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.
GO:1901252	regulation of intracellular transport of viral material	biological_process	Any process that modulates the frequency, rate or extent of egress of virus within host cell.
GO:1901253	negative regulation of intracellular transport of viral material	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.
GO:1901254	positive regulation of intracellular transport of viral material	biological_process	Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.
GO:1901255	nucleotide-excision repair involved in interstrand cross-link repair	biological_process	Any nucleotide-excision repair that is involved in interstrand cross-link repair.
GO:1901256	regulation of macrophage colony-stimulating factor production	biological_process	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.
GO:1901257	negative regulation of macrophage colony-stimulating factor production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.
GO:1901258	positive regulation of macrophage colony-stimulating factor production	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.
GO:1901259	chloroplast rRNA processing	biological_process	Any rRNA processing that takes place in chloroplast.
GO:1901260	peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification	biological_process	Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification.
GO:1901261	regulation of sorocarp spore cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.
GO:1901262	negative regulation of sorocarp spore cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.
GO:1901263	positive regulation of sorocarp spore cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.
GO:1901264	carbohydrate derivative transport	biological_process	The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901265	nucleoside phosphate binding	molecular_function	Binding to nucleoside phosphate.
GO:1901266	cephalosporin C metabolic process	biological_process	The chemical reactions and pathways involving cephalosporin C.
GO:1901267	cephalosporin C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cephalosporin C.
GO:1901268	cephalosporin C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cephalosporin C.
GO:1901269	lipooligosaccharide metabolic process	biological_process	The chemical reactions and pathways involving lipooligosaccharide.
GO:1901270	lipooligosaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.
GO:1901271	lipooligosaccharide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipooligosaccharide.
GO:1901272	2-dehydro-3-deoxy-D-gluconic acid metabolic process	biological_process	The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.
GO:1901273	2-dehydro-3-deoxy-D-gluconic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid.
GO:1901274	2-dehydro-3-deoxy-D-gluconic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid.
GO:1901275	tartrate metabolic process	biological_process	The chemical reactions and pathways involving tartrate.
GO:1901276	tartrate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tartrate.
GO:1901277	tartrate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tartrate.
GO:1901278	D-ribose 5-phosphate metabolic process	biological_process	The chemical reactions and pathways involving D-ribose 5-phosphate.
GO:1901279	D-ribose 5-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate.
GO:1901280	D-ribose 5-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate.
GO:1901281	fructoselysine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fructoselysine.
GO:1901282	fructoselysine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fructoselysine.
GO:1901283	5,6,7,8-tetrahydromethanopterin metabolic process	biological_process	The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.
GO:1901284	5,6,7,8-tetrahydromethanopterin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin.
GO:1901285	5,6,7,8-tetrahydromethanopterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin.
GO:1901286	iron-sulfur-molybdenum cofactor metabolic process	biological_process	The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.
GO:1901287	iron-sulfur-molybdenum cofactor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.
GO:1901288	iron-sulfur-molybdenum cofactor biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.
GO:1901289	succinyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.
GO:1901290	succinyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of succinyl-CoA.
GO:1901291	negative regulation of double-strand break repair via single-strand annealing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.
GO:1901292	nucleoside phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.
GO:1901293	nucleoside phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.
GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	biological_process	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
GO:1901296	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
GO:1901297	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	biological_process	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
GO:1901298	regulation of hydrogen peroxide-mediated programmed cell death	biological_process	Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	biological_process	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
GO:1901301	regulation of cargo loading into COPII-coated vesicle	biological_process	Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.
GO:1901303	negative regulation of cargo loading into COPII-coated vesicle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.
GO:1901304	regulation of spermidine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.
GO:1901305	negative regulation of spermidine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.
GO:1901307	positive regulation of spermidine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.
GO:1901314	regulation of histone H2A K63-linked ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination.
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.
GO:1901316	positive regulation of histone H2A K63-linked ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination.
GO:1901317	regulation of flagellated sperm motility	biological_process	Any process that modulates the frequency, rate or extent of flagellated sperm motility.
GO:1901318	negative regulation of flagellated sperm motility	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.
GO:1901319	positive regulation of trehalose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.
GO:1901320	negative regulation of heart induction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heart induction.
GO:1901321	positive regulation of heart induction	biological_process	Any process that activates or increases the frequency, rate or extent of heart induction.
GO:1901322	response to chloramphenicol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.
GO:1901323	response to erythromycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.
GO:1901324	response to trichodermin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.
GO:1901325	response to antimycin A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.
GO:1901326	response to tetracycline	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.
GO:1901327	response to tacrolimus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.
GO:1901328	response to cytochalasin B	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.
GO:1901329	regulation of odontoblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of odontoblast differentiation.
GO:1901330	negative regulation of odontoblast differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.
GO:1901331	positive regulation of odontoblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.
GO:1901332	negative regulation of lateral root development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development.
GO:1901333	positive regulation of lateral root development	biological_process	Any process that activates or increases the frequency, rate or extent of lateral root development.
GO:1901334	lactone metabolic process	biological_process	The chemical reactions and pathways involving lactone.
GO:1901335	lactone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactone.
GO:1901336	lactone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lactone.
GO:1901337	thioester transport	biological_process	The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901338	catecholamine binding	molecular_function	Binding to catecholamine.
GO:1901339	regulation of store-operated calcium channel activity	biological_process	Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.
GO:1901340	negative regulation of store-operated calcium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.
GO:1901341	positive regulation of store-operated calcium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.
GO:1901342	regulation of vasculature development	biological_process	Any process that modulates the frequency, rate or extent of vasculature development.
GO:1901343	negative regulation of vasculature development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.
GO:1901344	response to leptomycin B	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.
GO:1901345	response to L-thialysine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.
GO:1901346	negative regulation of vasculature development involved in avascular cornea development in camera-type eye	biological_process	Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.
GO:1901347	negative regulation of secondary cell wall biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.
GO:1901348	positive regulation of secondary cell wall biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.
GO:1901349	glucosinolate transport	biological_process	The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901351	regulation of phosphatidylglycerol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
GO:1901352	negative regulation of phosphatidylglycerol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
GO:1901353	positive regulation of phosphatidylglycerol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
GO:1901354	response to L-canavanine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.
GO:1901355	response to rapamycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
GO:1901356	beta-D-galactofuranose metabolic process	biological_process	The chemical reactions and pathways involving beta-D-galactofuranose.
GO:1901357	beta-D-galactofuranose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.
GO:1901358	beta-D-galactofuranose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose.
GO:1901359	tungstate binding	molecular_function	Binding to tungstate.
GO:1901360	organic cyclic compound metabolic process	biological_process	The chemical reactions and pathways involving organic cyclic compound.
GO:1901361	organic cyclic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.
GO:1901362	organic cyclic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organic cyclic compound.
GO:1901363	heterocyclic compound binding	molecular_function	Binding to heterocyclic compound.
GO:1901364	funalenone metabolic process	biological_process	The chemical reactions and pathways involving funalenone.
GO:1901365	funalenone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of funalenone.
GO:1901366	funalenone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of funalenone.
GO:1901367	response to L-cysteine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.
GO:1901369	cyclic 2,3-bisphospho-D-glycerate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid.
GO:1901370	response to glutathione	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.
GO:1901371	regulation of leaf morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of leaf morphogenesis.
GO:1901373	lipid hydroperoxide transport	biological_process	The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901374	acetate ester transport	biological_process	The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901375	acetate ester transmembrane transporter activity	molecular_function	Enables the transfer of an acetate ester from one side of a membrane to the other.
GO:1901376	organic heteropentacyclic compound metabolic process	biological_process	The chemical reactions and pathways involving organic heteropentacyclic compound.
GO:1901377	organic heteropentacyclic compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.
GO:1901378	organic heteropentacyclic compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.
GO:1901379	regulation of potassium ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
GO:1901380	negative regulation of potassium ion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.
GO:1901381	positive regulation of potassium ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.
GO:1901382	regulation of chorionic trophoblast cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.
GO:1901383	negative regulation of chorionic trophoblast cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.
GO:1901384	positive regulation of chorionic trophoblast cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.
GO:1901385	regulation of voltage-gated calcium channel activity	biological_process	Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.
GO:1901386	negative regulation of voltage-gated calcium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
GO:1901387	positive regulation of voltage-gated calcium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.
GO:1901388	regulation of transforming growth factor beta activation	biological_process	Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.
GO:1901389	negative regulation of transforming growth factor beta activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.
GO:1901390	positive regulation of transforming growth factor beta activation	biological_process	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation.
GO:1901392	regulation of transforming growth factor beta1 activation	biological_process	Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation.
GO:1901393	negative regulation of transforming growth factor beta1 activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation.
GO:1901394	positive regulation of transforming growth factor beta1 activation	biological_process	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation.
GO:1901395	regulation of transforming growth factor beta2 activation	biological_process	Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation.
GO:1901396	negative regulation of transforming growth factor beta2 activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.
GO:1901397	positive regulation of transforming growth factor beta2 activation	biological_process	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.
GO:1901398	regulation of transforming growth factor beta3 activation	biological_process	Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.
GO:1901399	negative regulation of transforming growth factor beta3 activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation.
GO:1901400	positive regulation of transforming growth factor beta3 activation	biological_process	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.
GO:1901401	regulation of tetrapyrrole metabolic process	biological_process	Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.
GO:1901402	negative regulation of tetrapyrrole metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.
GO:1901403	positive regulation of tetrapyrrole metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.
GO:1901404	regulation of tetrapyrrole catabolic process	biological_process	Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.
GO:1901405	negative regulation of tetrapyrrole catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.
GO:1901406	positive regulation of tetrapyrrole catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.
GO:1901410	regulation of tetrapyrrole biosynthetic process from glutamate	biological_process	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
GO:1901411	negative regulation of tetrapyrrole biosynthetic process from glutamate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
GO:1901412	positive regulation of tetrapyrrole biosynthetic process from glutamate	biological_process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
GO:1901413	regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	biological_process	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
GO:1901414	negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
GO:1901415	positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	biological_process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
GO:1901416	regulation of response to ethanol	biological_process	Any process that modulates the frequency, rate or extent of response to ethanol.
GO:1901417	negative regulation of response to ethanol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol.
GO:1901418	positive regulation of response to ethanol	biological_process	Any process that activates or increases the frequency, rate or extent of response to ethanol.
GO:1901419	regulation of response to alcohol	biological_process	Any process that modulates the frequency, rate or extent of response to alcohol.
GO:1901420	negative regulation of response to alcohol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.
GO:1901421	positive regulation of response to alcohol	biological_process	Any process that activates or increases the frequency, rate or extent of response to alcohol.
GO:1901422	response to butan-1-ol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.
GO:1901423	response to benzene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.
GO:1901424	response to toluene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus.
GO:1901425	response to formic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.
GO:1901426	response to furfural	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus.
GO:1901427	response to propan-1-ol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.
GO:1901428	regulation of syringal lignin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.
GO:1901429	negative regulation of syringal lignin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.
GO:1901430	positive regulation of syringal lignin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process.
GO:1901431	regulation of response to cycloalkane	biological_process	Any process that modulates the frequency, rate or extent of response to cycloalkane.
GO:1901432	negative regulation of response to cycloalkane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane.
GO:1901433	positive regulation of response to cycloalkane	biological_process	Any process that activates or increases the frequency, rate or extent of response to cycloalkane.
GO:1901434	regulation of toluene catabolic process	biological_process	Any process that modulates the frequency, rate or extent of toluene catabolic process.
GO:1901435	negative regulation of toluene catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.
GO:1901436	positive regulation of toluene catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of toluene catabolic process.
GO:1901437	regulation of toluene metabolic process	biological_process	Any process that modulates the frequency, rate or extent of toluene metabolic process.
GO:1901438	negative regulation of toluene metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.
GO:1901439	positive regulation of toluene metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of toluene metabolic process.
GO:1901440	poly(hydroxyalkanoate) metabolic process	biological_process	The chemical reactions and pathways involving poly(hydroxyalkanoate).
GO:1901441	poly(hydroxyalkanoate) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).
GO:1901442	regulation of response to furfural	biological_process	Any process that modulates the frequency, rate or extent of response to furfural.
GO:1901443	negative regulation of response to furfural	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural.
GO:1901444	positive regulation of response to furfural	biological_process	Any process that activates or increases the frequency, rate or extent of response to furfural.
GO:1901445	regulation of response to propan-1-ol	biological_process	Any process that modulates the frequency, rate or extent of response to propan-1-ol.
GO:1901446	negative regulation of response to propan-1-ol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.
GO:1901447	positive regulation of response to propan-1-ol	biological_process	Any process that activates or increases the frequency, rate or extent of response to propan-1-ol.
GO:1901448	regulation of response to butan-1-ol	biological_process	Any process that modulates the frequency, rate or extent of response to butan-1-ol.
GO:1901449	negative regulation of response to butan-1-ol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol.
GO:1901450	positive regulation of response to butan-1-ol	biological_process	Any process that activates or increases the frequency, rate or extent of response to butan-1-ol.
GO:1901451	regulation of response to benzene	biological_process	Any process that modulates the frequency, rate or extent of response to benzene.
GO:1901452	negative regulation of response to benzene	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.
GO:1901453	positive regulation of response to benzene	biological_process	Any process that activates or increases the frequency, rate or extent of response to benzene.
GO:1901454	regulation of response to toluene	biological_process	Any process that modulates the frequency, rate or extent of response to toluene.
GO:1901455	negative regulation of response to toluene	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene.
GO:1901456	positive regulation of response to toluene	biological_process	Any process that activates or increases the frequency, rate or extent of response to toluene.
GO:1901457	regulation of response to acetate	biological_process	Any process that modulates the frequency, rate or extent of response to acetate.
GO:1901458	negative regulation of response to acetate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.
GO:1901459	positive regulation of response to acetate	biological_process	Any process that activates or increases the frequency, rate or extent of response to acetate.
GO:1901460	regulation of response to formic acid	biological_process	Any process that modulates the frequency, rate or extent of response to formic acid.
GO:1901461	negative regulation of response to formic acid	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.
GO:1901462	positive regulation of response to formic acid	biological_process	Any process that activates or increases the frequency, rate or extent of response to formic acid.
GO:1901463	regulation of tetrapyrrole biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.
GO:1901464	negative regulation of tetrapyrrole biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.
GO:1901465	positive regulation of tetrapyrrole biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.
GO:1901466	regulation of ferulate catabolic process	biological_process	Any process that modulates the frequency, rate or extent of ferulate catabolic process.
GO:1901467	negative regulation of ferulate catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process.
GO:1901468	positive regulation of ferulate catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ferulate catabolic process.
GO:1901469	regulation of syringal lignin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.
GO:1901470	negative regulation of syringal lignin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.
GO:1901471	positive regulation of syringal lignin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.
GO:1901472	regulation of Golgi calcium ion export	biological_process	Any process that modulates the frequency, rate or extent of Golgi calcium ion export.
GO:1901474	azole transmembrane transporter activity	molecular_function	Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.
GO:1901475	pyruvate transmembrane transport	biological_process	The directed movement of pyruvate across a membrane.
GO:1901478	aminotriazole transmembrane transporter activity	molecular_function	Enables the transfer of amitrole from one side of a membrane to the other.
GO:1901480	oleate transmembrane transporter activity	molecular_function	Enables the transfer of oleate from one side of a membrane to the other.
GO:1901481	L-glutamate import involved in cellular response to nitrogen starvation	biological_process	Any L-glutamate import that is involved in cellular response to nitrogen starvation.
GO:1901482	L-lysine import into vacuole involved in cellular response to nitrogen starvation	biological_process	A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation.
GO:1901490	regulation of lymphangiogenesis	biological_process	Any process that modulates the frequency, rate or extent of lymphangiogenesis.
GO:1901491	negative regulation of lymphangiogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.
GO:1901492	positive regulation of lymphangiogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.
GO:1901493	response to decalin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.
GO:1901494	regulation of cysteine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cysteine metabolic process.
GO:1901495	negative regulation of cysteine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process.
GO:1901496	positive regulation of cysteine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cysteine metabolic process.
GO:1901497	response to diphenyl ether	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus.
GO:1901498	response to tetralin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus.
GO:1901499	response to hexane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus.
GO:1901500	response to p-xylene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.
GO:1901501	response to xylene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus.
GO:1901502	ether catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ether.
GO:1901503	ether biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ether.
GO:1901504	triazole transport	biological_process	The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901505	carbohydrate derivative transmembrane transporter activity	molecular_function	Enables the transfer of carbohydrate derivative from one side of a membrane to the other.
GO:1901506	regulation of acylglycerol transport	biological_process	Any process that modulates the frequency, rate or extent of acylglycerol transport.
GO:1901507	negative regulation of acylglycerol transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.
GO:1901508	positive regulation of acylglycerol transport	biological_process	Any process that activates or increases the frequency, rate or extent of acylglycerol transport.
GO:1901509	regulation of endothelial tube morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.
GO:1901510	(-)-microperfuranone metabolic process	biological_process	The chemical reactions and pathways involving (-)-microperfuranone.
GO:1901511	(-)-microperfuranone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone.
GO:1901512	(-)-microperfuranone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-microperfuranone.
GO:1901513	lipo-chitin oligosaccharide transmembrane transporter activity	molecular_function	Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.
GO:1901514	ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out).
GO:1901515	poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity	molecular_function	Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other.
GO:1901516	aspyridone A metabolic process	biological_process	The chemical reactions and pathways involving aspyridone A.
GO:1901517	aspyridone A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aspyridone A.
GO:1901518	aspyridone A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aspyridone A.
GO:1901519	aspyridone B metabolic process	biological_process	The chemical reactions and pathways involving aspyridone B.
GO:1901520	aspyridone B catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of aspyridone B.
GO:1901521	aspyridone B biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aspyridone B.
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	biological_process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.
GO:1901523	icosanoid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of icosanoid.
GO:1901524	regulation of mitophagy	biological_process	Any process that modulates the frequency, rate or extent of macromitophagy.
GO:1901525	negative regulation of mitophagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy.
GO:1901526	positive regulation of mitophagy	biological_process	Any process that activates or increases the frequency, rate or extent of mitophagy.
GO:1901527	abscisic acid-activated signaling pathway involved in stomatal movement	biological_process	Any abscisic acid mediated signaling pathway that is involved in stomatal movement.
GO:1901528	hydrogen peroxide mediated signaling pathway involved in stomatal movement	biological_process	Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement.
GO:1901529	positive regulation of anion channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of anion channel activity.
GO:1901530	response to hypochlorite	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.
GO:1901531	hypochlorite binding	molecular_function	Binding to hypochlorite.
GO:1901532	regulation of hematopoietic progenitor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.
GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.
GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.
GO:1901535	regulation of DNA demethylation	biological_process	Any process that modulates the frequency, rate or extent of DNA demethylation.
GO:1901536	negative regulation of DNA demethylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.
GO:1901537	positive regulation of DNA demethylation	biological_process	Any process that activates or increases the frequency, rate or extent of DNA demethylation.
GO:1901539	ent-pimara-8(14),15-diene metabolic process	biological_process	The chemical reactions and pathways involving ent-pimara-8(14),15-diene.
GO:1901540	ent-pimara-8(14),15-diene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene.
GO:1901541	ent-pimara-8(14),15-diene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene.
GO:1901542	regulation of ent-pimara-8(14),15-diene biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
GO:1901543	negative regulation of ent-pimara-8(14),15-diene biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
GO:1901544	positive regulation of ent-pimara-8(14),15-diene biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
GO:1901545	response to raffinose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
GO:1901546	regulation of synaptic vesicle lumen acidification	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.
GO:1901547	negative regulation of synaptic vesicle lumen acidification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification.
GO:1901548	positive regulation of synaptic vesicle lumen acidification	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.
GO:1901550	regulation of endothelial cell development	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell development.
GO:1901551	negative regulation of endothelial cell development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.
GO:1901552	positive regulation of endothelial cell development	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell development.
GO:1901553	malonic acid transmembrane transport	biological_process	The directed movement of malonic acid across a membrane.
GO:1901554	response to paracetamol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.
GO:1901556	response to candesartan	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.
GO:1901557	response to fenofibrate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.
GO:1901558	response to metformin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.
GO:1901559	response to ribavirin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.
GO:1901560	response to purvalanol A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.
GO:1901562	response to paraquat	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
GO:1901563	response to camptothecin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
GO:1901564	organonitrogen compound metabolic process	biological_process	The chemical reactions and pathways involving organonitrogen compound.
GO:1901565	organonitrogen compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.
GO:1901566	organonitrogen compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organonitrogen compound.
GO:1901567	fatty acid derivative binding	molecular_function	Binding to fatty acid derivative.
GO:1901568	fatty acid derivative metabolic process	biological_process	The chemical reactions and pathways involving fatty acid derivative.
GO:1901569	fatty acid derivative catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.
GO:1901570	fatty acid derivative biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fatty acid derivative.
GO:1901571	fatty acid derivative transport	biological_process	The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901575	organic substance catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.
GO:1901576	organic substance biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:1901577	regulation of alkane biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of alkane biosynthetic process.
GO:1901578	negative regulation of alkane biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.
GO:1901579	positive regulation of alkane biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.
GO:1901583	tetrapeptide import across plasma membrane	biological_process	The directed movement of a tetrapeptide from outside of a cell, across the plasma membrane and into the cytosol.
GO:1901584	tetrapeptide transmembrane transporter activity	molecular_function	Enables the transfer of tetrapeptide from one side of a membrane to the other.
GO:1901585	regulation of acid-sensing ion channel activity	biological_process	Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity.
GO:1901586	negative regulation of acid-sensing ion channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity.
GO:1901587	positive regulation of acid-sensing ion channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity.
GO:1901588	dendritic microtubule	cellular_component	Any microtubule in a dendrite, a neuron projection.
GO:1901589	axon microtubule bundle	cellular_component	An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.
GO:1901591	regulation of double-strand break repair via break-induced replication	biological_process	Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.
GO:1901592	negative regulation of double-strand break repair via break-induced replication	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.
GO:1901593	response to GW 7647	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.
GO:1901594	response to capsazepine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.
GO:1901595	response to hesperadin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.
GO:1901596	response to reversine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.
GO:1901597	response to carbendazim	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.
GO:1901598	(-)-pinoresinol metabolic process	biological_process	The chemical reactions and pathways involving (-)-pinoresinol.
GO:1901599	(-)-pinoresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-pinoresinol.
GO:1901600	strigolactone metabolic process	biological_process	The chemical reactions and pathways involving strigolactone.
GO:1901601	strigolactone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of strigolactone.
GO:1901602	dethiobiotin binding	molecular_function	Binding to dethiobiotin.
GO:1901604	dethiobiotin transmembrane transporter activity	molecular_function	Enables the transfer of dethiobiotin from one side of a membrane to the other.
GO:1901605	alpha-amino acid metabolic process	biological_process	The chemical reactions and pathways involving an alpha-amino acid.
GO:1901606	alpha-amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.
GO:1901607	alpha-amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of an alpha-amino acid.
GO:1901608	regulation of vesicle transport along microtubule	biological_process	Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.
GO:1901609	negative regulation of vesicle transport along microtubule	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.
GO:1901610	positive regulation of vesicle transport along microtubule	biological_process	Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.
GO:1901611	phosphatidylglycerol binding	molecular_function	Binding to phosphatidylglycerol.
GO:1901612	cardiolipin binding	molecular_function	Binding to cardiolipin.
GO:1901613	negative regulation of terminal button organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization.
GO:1901614	positive regulation of terminal button organization	biological_process	Any process that activates or increases the frequency, rate or extent of terminal button organization.
GO:1901615	organic hydroxy compound metabolic process	biological_process	The chemical reactions and pathways involving organic hydroxy compound.
GO:1901616	organic hydroxy compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.
GO:1901617	organic hydroxy compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of organic hydroxy compound.
GO:1901618	organic hydroxy compound transmembrane transporter activity	molecular_function	Enables the transfer of organic hydroxy compound from one side of a membrane to the other.
GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	biological_process	Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
GO:1901622	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	biological_process	Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
GO:1901623	regulation of lymphocyte chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.
GO:1901624	negative regulation of lymphocyte chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.
GO:1901625	cellular response to ergosterol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.
GO:1901626	regulation of postsynaptic membrane organization	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.
GO:1901627	negative regulation of postsynaptic membrane organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.
GO:1901628	positive regulation of postsynaptic membrane organization	biological_process	Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.
GO:1901629	regulation of presynaptic membrane organization	biological_process	Any process that modulates the frequency, rate or extent of presynaptic membrane organization.
GO:1901630	negative regulation of presynaptic membrane organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.
GO:1901631	positive regulation of presynaptic membrane organization	biological_process	Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization.
GO:1901632	regulation of synaptic vesicle membrane organization	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.
GO:1901633	negative regulation of synaptic vesicle membrane organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.
GO:1901634	positive regulation of synaptic vesicle membrane organization	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization.
GO:1901640	XTP binding	molecular_function	Binding to XTP.
GO:1901641	ITP binding	molecular_function	Binding to ITP.
GO:1901642	nucleoside transmembrane transport	biological_process	The directed movement of nucleoside across a membrane.
GO:1901645	regulation of synoviocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of synoviocyte proliferation.
GO:1901646	negative regulation of synoviocyte proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.
GO:1901647	positive regulation of synoviocyte proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.
GO:1901652	response to peptide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
GO:1901653	cellular response to peptide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
GO:1901654	response to ketone	biological_process	A response that results in a state of tolerance to ketone.
GO:1901655	cellular response to ketone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.
GO:1901656	glycoside transport	biological_process	The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901657	glycosyl compound metabolic process	biological_process	The chemical reactions and pathways involving glycosyl compound.
GO:1901658	glycosyl compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycosyl compound.
GO:1901659	glycosyl compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycosyl compound.
GO:1901660	calcium ion export	biological_process	The directed movement of calcium ion out of a cell or organelle.
GO:1901661	quinone metabolic process	biological_process	The chemical reactions and pathways involving quinone.
GO:1901662	quinone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of quinone.
GO:1901663	quinone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of quinone.
GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
GO:1901665	negative regulation of NAD+ ADP-ribosyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
GO:1901667	negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration.
GO:1901668	regulation of superoxide dismutase activity	biological_process	Any process that modulates the frequency, rate or extent of superoxide dismutase activity.
GO:1901670	negative regulation of superoxide dismutase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity.
GO:1901671	positive regulation of superoxide dismutase activity	biological_process	Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.
GO:1901672	positive regulation of systemic acquired resistance	biological_process	Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.
GO:1901673	regulation of mitotic spindle assembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
GO:1901678	iron coordination entity transport	biological_process	The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901679	nucleotide transmembrane transport	biological_process	The directed movement of nucleotide across a membrane.
GO:1901680	sulfur-containing amino acid secondary active transmembrane transporter activity	molecular_function	Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
GO:1901681	sulfur compound binding	molecular_function	Binding to a sulfur compound.
GO:1901682	sulfur compound transmembrane transporter activity	molecular_function	Enables the transfer of a sulfur compound from one side of a membrane to the other.
GO:1901683	arsenate ion transmembrane transporter activity	molecular_function	Enables the transfer of an arsenate ion from one side of a membrane to the other.
GO:1901684	arsenate ion transmembrane transport	biological_process	The process in which arsenate is transported across a membrane.
GO:1901685	glutathione derivative metabolic process	biological_process	The chemical reactions and pathways involving glutathione derivative.
GO:1901686	glutathione derivative catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glutathione derivative.
GO:1901687	glutathione derivative biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glutathione derivative.
GO:1901691	proton binding	molecular_function	Binding to proton.
GO:1901692	regulation of compound eye retinal cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.
GO:1901693	negative regulation of compound eye retinal cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.
GO:1901694	positive regulation of compound eye retinal cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.
GO:1901695	tyramine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tyramine.
GO:1901696	cannabinoid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cannabinoid.
GO:1901697	olivetolic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of olivetolic acid.
GO:1901698	response to nitrogen compound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
GO:1901699	cellular response to nitrogen compound	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
GO:1901700	response to oxygen-containing compound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
GO:1901701	cellular response to oxygen-containing compound	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
GO:1901702	salt transmembrane transporter activity	molecular_function	Enables the transfer of salt from one side of a membrane to the other.
GO:1901703	protein localization involved in auxin polar transport	biological_process	Any protein localization that is involved in auxin polar transport.
GO:1901704	L-glutamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-glutamine.
GO:1901705	L-isoleucine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-isoleucine.
GO:1901706	mesenchymal cell differentiation involved in bone development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.
GO:1901707	leptomycin B binding	molecular_function	Binding to leptomycin B.
GO:1901708	(+)-3'-hydroxylarreatricin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin.
GO:1901709	(+)-larreatricin metabolic process	biological_process	The chemical reactions and pathways involving (+)-larreatricin.
GO:1901710	regulation of homoserine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of homoserine biosynthetic process.
GO:1901711	negative regulation of homoserine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process.
GO:1901712	positive regulation of homoserine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process.
GO:1901713	negative regulation of urea catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process.
GO:1901714	positive regulation of urea catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of urea catabolic process.
GO:1901715	regulation of gamma-aminobutyric acid catabolic process	biological_process	Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
GO:1901716	negative regulation of gamma-aminobutyric acid catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
GO:1901717	positive regulation of gamma-aminobutyric acid catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
GO:1901722	regulation of cell proliferation involved in kidney development	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.
GO:1901723	negative regulation of cell proliferation involved in kidney development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.
GO:1901724	positive regulation of cell proliferation involved in kidney development	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.
GO:1901725	regulation of histone deacetylase activity	biological_process	Any process that modulates the frequency, rate or extent of histone deacetylase activity.
GO:1901726	negative regulation of histone deacetylase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity.
GO:1901727	positive regulation of histone deacetylase activity	biological_process	Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.
GO:1901728	monensin A metabolic process	biological_process	The chemical reactions and pathways involving monensin A.
GO:1901729	monensin A catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monensin A.
GO:1901730	monensin A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monensin A.
GO:1901731	positive regulation of platelet aggregation	biological_process	Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
GO:1901732	quercetin metabolic process	biological_process	The chemical reactions and pathways involving quercetin.
GO:1901733	quercetin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of quercetin.
GO:1901734	quercetin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of quercetin.
GO:1901735	(R)-mevalonic acid metabolic process	biological_process	The chemical reactions and pathways involving (R)-mevalonic acid.
GO:1901736	(R)-mevalonic acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid.
GO:1901737	(R)-mevalonic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid.
GO:1901738	regulation of vitamin A metabolic process	biological_process	Any process that modulates the frequency, rate or extent of vitamin A metabolic process.
GO:1901739	regulation of myoblast fusion	biological_process	Any process that modulates the frequency, rate or extent of myoblast fusion.
GO:1901740	negative regulation of myoblast fusion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.
GO:1901741	positive regulation of myoblast fusion	biological_process	Any process that activates or increases the frequency, rate or extent of myoblast fusion.
GO:1901742	2-deoxystreptamine metabolic process	biological_process	The chemical reactions and pathways involving 2-deoxystreptamine.
GO:1901743	2-deoxystreptamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine.
GO:1901744	2-deoxystreptamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.
GO:1901745	prephenate(2-) metabolic process	biological_process	The chemical reactions and pathways involving prephenate(2-).
GO:1901746	prephenate(2-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prephenate(2-).
GO:1901747	prephenate(2-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of prephenate(2-).
GO:1901748	leukotriene D4 metabolic process	biological_process	The chemical reactions and pathways involving leukotriene D4.
GO:1901749	leukotriene D4 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of leukotriene D4.
GO:1901750	leukotriene D4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leukotriene D4.
GO:1901751	leukotriene A4 metabolic process	biological_process	The chemical reactions and pathways involving leukotriene A4.
GO:1901752	leukotriene A4 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of leukotriene A4.
GO:1901753	leukotriene A4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of leukotriene A4.
GO:1901754	vitamin D3 catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of vitamin D3.
GO:1901755	vitamin D3 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of vitamin D3.
GO:1901756	butirosin metabolic process	biological_process	The chemical reactions and pathways involving butirosin.
GO:1901757	butirosin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of butirosin.
GO:1901758	butirosin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of butirosin.
GO:1901759	beta-L-Ara4N-lipid A metabolic process	biological_process	The chemical reactions and pathways involving beta-L-Ara4N-lipid A.
GO:1901760	beta-L-Ara4N-lipid A biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.
GO:1901761	oxytetracycline metabolic process	biological_process	The chemical reactions and pathways involving oxytetracycline.
GO:1901762	oxytetracycline catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of oxytetracycline.
GO:1901763	oxytetracycline biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of oxytetracycline.
GO:1901764	phosphinothricin metabolic process	biological_process	The chemical reactions and pathways involving phosphinothricin.
GO:1901765	phosphinothricin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of phosphinothricin.
GO:1901766	phosphinothricin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphinothricin.
GO:1901767	carbapenem metabolic process	biological_process	The chemical reactions and pathways involving carbapenem.
GO:1901768	carbapenem catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of carbapenem.
GO:1901769	carbapenem biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of carbapenem.
GO:1901770	daunorubicin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of daunorubicin.
GO:1901771	daunorubicin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of daunorubicin.
GO:1901772	lincomycin metabolic process	biological_process	The chemical reactions and pathways involving lincomycin.
GO:1901773	lincomycin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lincomycin.
GO:1901774	lincomycin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lincomycin.
GO:1901775	mitomycin C metabolic process	biological_process	The chemical reactions and pathways involving mitomycin C.
GO:1901776	mitomycin C catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of mitomycin C.
GO:1901777	mitomycin C biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of mitomycin C.
GO:1901778	pentalenolactone metabolic process	biological_process	The chemical reactions and pathways involving pentalenolactone.
GO:1901779	pentalenolactone catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pentalenolactone.
GO:1901780	pentalenolactone biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of pentalenolactone.
GO:1901781	p-cumate metabolic process	biological_process	The chemical reactions and pathways involving p-cumate.
GO:1901782	p-cumate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of p-cumate.
GO:1901783	p-cumate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of p-cumate.
GO:1901784	p-cresol metabolic process	biological_process	The chemical reactions and pathways involving p-cresol.
GO:1901785	p-cresol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of p-cresol.
GO:1901786	p-cresol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of p-cresol.
GO:1901787	benzoyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving benzoyl-CoA.
GO:1901788	benzoyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA.
GO:1901789	benzoyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of benzoyl-CoA.
GO:1901790	3-(2,3-dihydroxyphenyl)propanoate metabolic process	biological_process	The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate.
GO:1901791	3-(2,3-dihydroxyphenyl)propanoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate.
GO:1901792	3-(2,3-dihydroxyphenyl)propanoate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate.
GO:1901793	3-(3-hydroxyphenyl)propanoate metabolic process	biological_process	The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.
GO:1901794	3-(3-hydroxyphenyl)propanoate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate.
GO:1901795	3-(3-hydroxyphenyl)propanoate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate.
GO:1901796	regulation of signal transduction by p53 class mediator	biological_process	Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
GO:1901797	negative regulation of signal transduction by p53 class mediator	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.
GO:1901798	positive regulation of signal transduction by p53 class mediator	biological_process	Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.
GO:1901799	negative regulation of proteasomal protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
GO:1901800	positive regulation of proteasomal protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.
GO:1901801	1,5-anhydro-D-fructose metabolic process	biological_process	The chemical reactions and pathways involving 1,5-anhydro-D-fructose.
GO:1901802	1,5-anhydro-D-fructose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.
GO:1901803	1,5-anhydro-D-fructose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose.
GO:1901804	beta-glucoside metabolic process	biological_process	The chemical reactions and pathways involving beta-glucoside.
GO:1901805	beta-glucoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-glucoside.
GO:1901806	beta-glucoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-glucoside.
GO:1901807	capsanthin metabolic process	biological_process	The chemical reactions and pathways involving capsanthin.
GO:1901808	capsanthin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of capsanthin.
GO:1901809	capsanthin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of capsanthin.
GO:1901810	beta-carotene metabolic process	biological_process	The chemical reactions and pathways involving beta-carotene.
GO:1901811	beta-carotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-carotene.
GO:1901812	beta-carotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-carotene.
GO:1901813	astaxanthin metabolic process	biological_process	The chemical reactions and pathways involving astaxanthin.
GO:1901814	astaxanthin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of astaxanthin.
GO:1901815	astaxanthin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of astaxanthin.
GO:1901816	beta-zeacarotene metabolic process	biological_process	The chemical reactions and pathways involving beta-zeacarotene.
GO:1901817	beta-zeacarotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.
GO:1901818	beta-zeacarotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-zeacarotene.
GO:1901819	alpha-zeacarotene metabolic process	biological_process	The chemical reactions and pathways involving alpha-zeacarotene.
GO:1901820	alpha-zeacarotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.
GO:1901821	alpha-zeacarotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alpha-zeacarotene.
GO:1901822	delta-carotene metabolic process	biological_process	The chemical reactions and pathways involving delta-carotene.
GO:1901823	delta-carotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of delta-carotene.
GO:1901824	delta-carotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of delta-carotene.
GO:1901825	zeaxanthin metabolic process	biological_process	The chemical reactions and pathways involving zeaxanthin.
GO:1901826	zeaxanthin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin.
GO:1901827	zeaxanthin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of zeaxanthin.
GO:1901828	zeaxanthin bis(beta-D-glucoside) metabolic process	biological_process	The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).
GO:1901829	zeaxanthin bis(beta-D-glucoside) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).
GO:1901830	zeaxanthin bis(beta-D-glucoside) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside).
GO:1901831	all-trans-neoxanthin metabolic process	biological_process	The chemical reactions and pathways involving all-trans-neoxanthin.
GO:1901832	all-trans-neoxanthin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin.
GO:1901833	all-trans-neoxanthin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.
GO:1901834	regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	biological_process	Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
GO:1901835	positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	biological_process	Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
GO:1901836	regulation of transcription of nucleolar large rRNA by RNA polymerase I	biological_process	Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.
GO:1901837	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.
GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	biological_process	Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.
GO:1901839	regulation of RNA polymerase I regulatory region sequence-specific DNA binding	biological_process	Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.
GO:1901840	negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.
GO:1901841	regulation of high voltage-gated calcium channel activity	biological_process	Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.
GO:1901842	negative regulation of high voltage-gated calcium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.
GO:1901843	positive regulation of high voltage-gated calcium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	biological_process	Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
GO:1901845	negative regulation of cell communication by electrical coupling involved in cardiac conduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
GO:1901846	positive regulation of cell communication by electrical coupling involved in cardiac conduction	biological_process	Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
GO:1901847	nicotinate metabolic process	biological_process	The chemical reactions and pathways involving nicotinate.
GO:1901848	nicotinate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of nicotinate.
GO:1901849	nicotinate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of nicotinate.
GO:1901850	7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process	biological_process	The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
GO:1901851	7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
GO:1901852	7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
GO:1901853	5,6,7,8-tetrahydrosarcinapterin metabolic process	biological_process	The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin.
GO:1901854	5,6,7,8-tetrahydrosarcinapterin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin.
GO:1901855	5,6,7,8-tetrahydrosarcinapterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.
GO:1901856	negative regulation of cellular respiration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.
GO:1901857	positive regulation of cellular respiration	biological_process	Any process that activates or increases the frequency, rate or extent of cellular respiration.
GO:1901858	regulation of mitochondrial DNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
GO:1901859	negative regulation of mitochondrial DNA metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
GO:1901860	positive regulation of mitochondrial DNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
GO:1901861	regulation of muscle tissue development	biological_process	Any process that modulates the frequency, rate or extent of muscle tissue development.
GO:1901862	negative regulation of muscle tissue development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.
GO:1901863	positive regulation of muscle tissue development	biological_process	Any process that activates or increases the frequency, rate or extent of muscle tissue development.
GO:1901864	capsorubin metabolic process	biological_process	The chemical reactions and pathways involving capsorubin.
GO:1901865	capsorubin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of capsorubin.
GO:1901866	capsorubin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of capsorubin.
GO:1901867	ecgonine methyl ester metabolic process	biological_process	The chemical reactions and pathways involving ecgonine methyl ester.
GO:1901868	ecgonine methyl ester catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.
GO:1901869	ecgonine methyl ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ecgonine methyl ester.
GO:1901870	ecgonone methyl ester metabolic process	biological_process	The chemical reactions and pathways involving ecgonone methyl ester.
GO:1901871	ecgonone methyl ester catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester.
GO:1901872	ecgonone methyl ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.
GO:1901873	regulation of post-translational protein modification	biological_process	Any process that modulates the frequency, rate or extent of post-translational protein modification.
GO:1901874	negative regulation of post-translational protein modification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.
GO:1901875	positive regulation of post-translational protein modification	biological_process	Any process that activates or increases the frequency, rate or extent of post-translational protein modification.
GO:1901876	regulation of calcium ion binding	biological_process	Any process that modulates the frequency, rate or extent of calcium ion binding.
GO:1901877	negative regulation of calcium ion binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.
GO:1901878	positive regulation of calcium ion binding	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion binding.
GO:1901879	regulation of protein depolymerization	biological_process	Any process that modulates the frequency, rate or extent of protein depolymerization.
GO:1901880	negative regulation of protein depolymerization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.
GO:1901881	positive regulation of protein depolymerization	biological_process	Any process that activates or increases the frequency, rate or extent of protein depolymerization.
GO:1901882	4-hydroxycoumarin metabolic process	biological_process	The chemical reactions and pathways involving 4-hydroxycoumarin.
GO:1901883	4-hydroxycoumarin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin.
GO:1901884	4-hydroxycoumarin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.
GO:1901885	2-hydroxybenzoyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.
GO:1901886	2-hydroxybenzoyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.
GO:1901887	2-hydroxybenzoyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.
GO:1901888	regulation of cell junction assembly	biological_process	Any process that modulates the frequency, rate or extent of cell junction assembly.
GO:1901889	negative regulation of cell junction assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.
GO:1901890	positive regulation of cell junction assembly	biological_process	Any process that activates or increases the frequency, rate or extent of cell junction assembly.
GO:1901891	regulation of cell septum assembly	biological_process	Any process that modulates the frequency, rate or extent of cell septum assembly.
GO:1901892	negative regulation of cell septum assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.
GO:1901893	positive regulation of cell septum assembly	biological_process	Any process that activates or increases the frequency, rate or extent of cell septum assembly.
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
GO:1901895	negative regulation of ATPase-coupled calcium transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
GO:1901896	positive regulation of ATPase-coupled calcium transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
GO:1901897	regulation of relaxation of cardiac muscle	biological_process	Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.
GO:1901898	negative regulation of relaxation of cardiac muscle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.
GO:1901899	positive regulation of relaxation of cardiac muscle	biological_process	Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.
GO:1901900	regulation of protein localization to cell division site	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell division site.
GO:1901901	regulation of protein localization to cell division site involved in cytokinesis	biological_process	Any regulation of protein localization to cell division site that is involved in cytokinesis.
GO:1901902	tyrocidine metabolic process	biological_process	The chemical reactions and pathways involving tyrocidine.
GO:1901903	tyrocidine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of tyrocidine.
GO:1901904	tyrocidine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tyrocidine.
GO:1901905	response to tamsulosin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.
GO:1901906	diadenosine pentaphosphate metabolic process	biological_process	The chemical reactions and pathways involving diadenosine pentaphosphate.
GO:1901907	diadenosine pentaphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.
GO:1901908	diadenosine hexaphosphate metabolic process	biological_process	The chemical reactions and pathways involving diadenosine hexaphosphate.
GO:1901909	diadenosine hexaphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.
GO:1901910	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	biological_process	The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate).
GO:1901911	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).
GO:1901913	regulation of capsule organization	biological_process	Any process that modulates the frequency, rate or extent of capsule organization.
GO:1901914	negative regulation of capsule organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.
GO:1901915	positive regulation of capsule organization	biological_process	Any process that activates or increases the frequency, rate or extent of capsule organization.
GO:1901917	regulation of exoribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of exoribonuclease activity.
GO:1901918	negative regulation of exoribonuclease activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.
GO:1901919	positive regulation of exoribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.
GO:1901920	peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity	biological_process	Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity.
GO:1901922	regulation of sclerotium development	biological_process	Any process that modulates the frequency, rate or extent of sclerotium development.
GO:1901923	negative regulation of sclerotium development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.
GO:1901924	positive regulation of sclerotium development	biological_process	Any process that activates or increases the frequency, rate or extent of sclerotium development.
GO:1901925	negative regulation of protein import into nucleus during spindle assembly checkpoint	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).
GO:1901926	cadinene metabolic process	biological_process	The chemical reactions and pathways involving cadinene.
GO:1901927	cadinene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cadinene.
GO:1901928	cadinene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cadinene.
GO:1901929	alpha-copaene metabolic process	biological_process	The chemical reactions and pathways involving alpha-copaene.
GO:1901930	alpha-copaene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of alpha-copaene.
GO:1901931	alpha-copaene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of alpha-copaene.
GO:1901932	bicyclogermacrene metabolic process	biological_process	The chemical reactions and pathways involving bicyclogermacrene.
GO:1901933	bicyclogermacrene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene.
GO:1901934	bicyclogermacrene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of bicyclogermacrene.
GO:1901935	beta-caryophyllene metabolic process	biological_process	The chemical reactions and pathways involving beta-caryophyllene.
GO:1901936	beta-caryophyllene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.
GO:1901937	beta-caryophyllene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of beta-caryophyllene.
GO:1901938	(-)-exo-alpha-bergamotene metabolic process	biological_process	The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.
GO:1901939	(-)-exo-alpha-bergamotene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.
GO:1901940	(-)-exo-alpha-bergamotene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene.
GO:1901941	(+)-epi-alpha-bisabolol metabolic process	biological_process	The chemical reactions and pathways involving (+)-epi-alpha-bisabolol.
GO:1901942	(+)-epi-alpha-bisabolol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.
GO:1901943	(+)-epi-alpha-bisabolol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.
GO:1901944	miltiradiene metabolic process	biological_process	The chemical reactions and pathways involving miltiradiene.
GO:1901945	miltiradiene catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of miltiradiene.
GO:1901946	miltiradiene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of miltiradiene.
GO:1901947	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process	biological_process	The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
GO:1901948	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
GO:1901949	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
GO:1901950	dense core granule transport	biological_process	The directed movement a dense core granule within a cell.
GO:1901951	regulation of anterograde dense core granule transport	biological_process	Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.
GO:1901952	negative regulation of anterograde dense core granule transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.
GO:1901953	positive regulation of anterograde dense core granule transport	biological_process	Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.
GO:1901954	regulation of retrograde dense core granule transport	biological_process	Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.
GO:1901955	negative regulation of retrograde dense core granule transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.
GO:1901956	positive regulation of retrograde dense core granule transport	biological_process	Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.
GO:1901957	regulation of cutin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of cutin biosynthetic process.
GO:1901958	negative regulation of cutin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.
GO:1901959	positive regulation of cutin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.
GO:1901960	isobutanol metabolic process	biological_process	The chemical reactions and pathways involving isobutanol.
GO:1901961	isobutanol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isobutanol.
GO:1901962	S-adenosyl-L-methionine transmembrane transport	biological_process	The directed movement of S-adenosyl-L-methionine across a membrane.
GO:1901963	regulation of cell proliferation involved in outflow tract morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.
GO:1901964	positive regulation of cell proliferation involved in outflow tract morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.
GO:1901965	endoplasmic reticulum to chloroplast transport	biological_process	The directed movement of substances from endoplasmic reticulum to chloroplast.
GO:1901966	regulation of cellular response to iron ion starvation	biological_process	Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.
GO:1901967	negative regulation of cellular response to iron ion starvation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.
GO:1901968	regulation of polynucleotide 3'-phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.
GO:1901969	positive regulation of polynucleotide 3'-phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.
GO:1901970	positive regulation of mitotic sister chromatid separation	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.
GO:1901973	proline binding	molecular_function	Binding to proline.
GO:1901974	glycerate transmembrane transporter activity	molecular_function	Enables the transfer of glycerate from one side of a membrane to the other.
GO:1901975	glycerate transmembrane transport	biological_process	The process in which glycerate is transported across a membrane.
GO:1901976	regulation of cell cycle checkpoint	biological_process	Any process that modulates the frequency, rate or extent of cell cycle checkpoint.
GO:1901977	negative regulation of cell cycle checkpoint	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
GO:1901978	positive regulation of cell cycle checkpoint	biological_process	Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.
GO:1901979	regulation of inward rectifier potassium channel activity	biological_process	Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.
GO:1901980	positive regulation of inward rectifier potassium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity.
GO:1901981	phosphatidylinositol phosphate binding	molecular_function	Binding to phosphatidylinositol phosphate.
GO:1901982	maltose binding	molecular_function	Binding to maltose.
GO:1901983	regulation of protein acetylation	biological_process	Any process that modulates the frequency, rate or extent of protein acetylation.
GO:1901984	negative regulation of protein acetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.
GO:1901985	positive regulation of protein acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein acetylation.
GO:1901986	response to ketamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.
GO:1901987	regulation of cell cycle phase transition	biological_process	Any process that modulates the frequency, rate or extent of cell cycle phase transition.
GO:1901988	negative regulation of cell cycle phase transition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.
GO:1901989	positive regulation of cell cycle phase transition	biological_process	Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.
GO:1901990	regulation of mitotic cell cycle phase transition	biological_process	Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
GO:1901991	negative regulation of mitotic cell cycle phase transition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.
GO:1901992	positive regulation of mitotic cell cycle phase transition	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.
GO:1901993	regulation of meiotic cell cycle phase transition	biological_process	Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition.
GO:1901994	negative regulation of meiotic cell cycle phase transition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition.
GO:1901995	positive regulation of meiotic cell cycle phase transition	biological_process	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.
GO:1901996	regulation of indoleacetic acid biosynthetic process via tryptophan	biological_process	Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.
GO:1901997	negative regulation of indoleacetic acid biosynthetic process via tryptophan	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.
GO:1901998	toxin transport	biological_process	The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1901999	homogentisate metabolic process	biological_process	The chemical reactions and pathways involving homogentisate.
GO:1902000	homogentisate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of homogentisate.
GO:1902001	fatty acid transmembrane transport	biological_process	The process in which a fatty acid is transported across a membrane.
GO:1902003	regulation of amyloid-beta formation	biological_process	Any process that modulates the frequency, rate or extent of amyloid-beta formation.
GO:1902004	positive regulation of amyloid-beta formation	biological_process	Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.
GO:1902005	regulation of proline biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of proline biosynthetic process.
GO:1902006	negative regulation of proline biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process.
GO:1902007	regulation of toxin transport	biological_process	Any process that modulates the frequency, rate or extent of toxin transport.
GO:1902008	negative regulation of toxin transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport.
GO:1902009	positive regulation of toxin transport	biological_process	Any process that activates or increases the frequency, rate or extent of toxin transport.
GO:1902010	negative regulation of translation in response to endoplasmic reticulum stress	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
GO:1902011	poly(ribitol phosphate) teichoic acid metabolic process	biological_process	The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.
GO:1902012	poly(ribitol phosphate) teichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.
GO:1902013	poly(glycerol phosphate) teichoic acid metabolic process	biological_process	The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid.
GO:1902014	poly(glycerol phosphate) teichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.
GO:1902015	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process	biological_process	The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
GO:1902016	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
GO:1902017	regulation of cilium assembly	biological_process	Any process that modulates the frequency, rate or extent of cilium assembly.
GO:1902018	negative regulation of cilium assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
GO:1902019	regulation of cilium-dependent cell motility	biological_process	Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.
GO:1902020	negative regulation of cilium-dependent cell motility	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.
GO:1902021	regulation of bacterial-type flagellum-dependent cell motility	biological_process	Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
GO:1902022	L-lysine transport	biological_process	The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1902024	L-histidine transport	biological_process	The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1902025	nitrate import	biological_process	The directed movement of nitrate into a cell or organelle.
GO:1902026	regulation of cartilage condensation	biological_process	Any process that modulates the frequency, rate or extent of cartilage condensation.
GO:1902027	positive regulation of cartilage condensation	biological_process	Any process that activates or increases the frequency, rate or extent of cartilage condensation.
GO:1902031	regulation of NADP metabolic process	biological_process	Any process that modulates the frequency, rate or extent of NADP metabolic process.
GO:1902033	regulation of hematopoietic stem cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.
GO:1902034	negative regulation of hematopoietic stem cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.
GO:1902035	positive regulation of hematopoietic stem cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.
GO:1902036	regulation of hematopoietic stem cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
GO:1902037	negative regulation of hematopoietic stem cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.
GO:1902038	positive regulation of hematopoietic stem cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.
GO:1902039	negative regulation of seed dormancy process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process.
GO:1902040	positive regulation of seed dormancy process	biological_process	Any process that activates or increases the frequency, rate or extent of seed dormancy process.
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological_process	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	biological_process	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
GO:1902044	regulation of Fas signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of Fas signaling pathway.
GO:1902045	negative regulation of Fas signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.
GO:1902046	positive regulation of Fas signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.
GO:1902047	polyamine transmembrane transport	biological_process	The process in which a polyamine macromolecule is transported across a membrane.
GO:1902048	neosartoricin metabolic process	biological_process	The chemical reactions and pathways involving neosartoricin.
GO:1902049	neosartoricin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of neosartoricin.
GO:1902050	neosartoricin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of neosartoricin.
GO:1902051	(25S)-Delta(4)-dafachronate binding	molecular_function	Binding to (25S)-Delta(4)-dafachronate.
GO:1902052	(25S)-Delta(7)-dafachronate binding	molecular_function	Binding to (25S)-Delta(7)-dafachronate.
GO:1902053	regulation of neosartoricin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process.
GO:1902054	negative regulation of neosartoricin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process.
GO:1902055	positive regulation of neosartoricin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process.
GO:1902056	(25S)-Delta(7)-dafachronate metabolic process	biological_process	The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate.
GO:1902057	(25S)-Delta(4)-dafachronate metabolic process	biological_process	The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.
GO:1902058	regulation of sporocarp development involved in sexual reproduction	biological_process	Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction.
GO:1902059	negative regulation of sporocarp development involved in sexual reproduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.
GO:1902060	positive regulation of sporocarp development involved in sexual reproduction	biological_process	Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.
GO:1902061	betaine aldehyde metabolic process	biological_process	The chemical reactions and pathways involving betaine aldehyde.
GO:1902062	betaine aldehyde catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.
GO:1902063	betaine aldehyde biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of betaine aldehyde.
GO:1902065	response to L-glutamate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.
GO:1902066	regulation of cell wall pectin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.
GO:1902068	regulation of sphingolipid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of sphingolipid signaling.
GO:1902069	negative regulation of sphingolipid mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.
GO:1902070	positive regulation of sphingolipid mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of sphingolipid signaling.
GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
GO:1902072	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
GO:1902074	response to salt	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
GO:1902075	cellular response to salt	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
GO:1902076	regulation of lateral motor column neuron migration	biological_process	Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.
GO:1902077	negative regulation of lateral motor column neuron migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.
GO:1902078	positive regulation of lateral motor column neuron migration	biological_process	Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.
GO:1902079	D-valine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of D-valine.
GO:1902080	regulation of calcium ion import into sarcoplasmic reticulum	biological_process	Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
GO:1902081	negative regulation of calcium ion import into sarcoplasmic reticulum	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
GO:1902082	positive regulation of calcium ion import into sarcoplasmic reticulum	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
GO:1902084	fumagillin metabolic process	biological_process	The chemical reactions and pathways involving fumagillin.
GO:1902085	fumagillin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fumagillin.
GO:1902086	fumagillin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fumagillin.
GO:1902087	dimethylsulfoniopropionate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.
GO:1902088	plant-type cell wall loosening involved in abscission	biological_process	Any plant-type cell wall loosening that is involved in abscission.
GO:1902089	cell wall polysaccharide catabolic process involved in lateral root development	biological_process	Any cell wall polysaccharide catabolic process that is involved in lateral root development.
GO:1902090	regulation of fumagillin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.
GO:1902091	negative regulation of fumagillin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.
GO:1902092	positive regulation of fumagillin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.
GO:1902093	positive regulation of flagellated sperm motility	biological_process	Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.
GO:1902097	positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium	biological_process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium.
GO:1902098	calcitriol binding	molecular_function	Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	biological_process	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
GO:1902102	regulation of metaphase/anaphase transition of meiotic cell cycle	biological_process	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
GO:1902104	positive regulation of metaphase/anaphase transition of meiotic cell cycle	biological_process	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
GO:1902105	regulation of leukocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of leukocyte differentiation.
GO:1902106	negative regulation of leukocyte differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.
GO:1902107	positive regulation of leukocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	biological_process	Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	biological_process	Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	biological_process	Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.
GO:1902111	response to diethyl maleate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.
GO:1902112	cellular response to diethyl maleate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.
GO:1902114	D-valine metabolic process	biological_process	The chemical reactions and pathways involving D-valine.
GO:1902115	regulation of organelle assembly	biological_process	Any process that modulates the frequency, rate or extent of organelle assembly.
GO:1902116	negative regulation of organelle assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
GO:1902117	positive regulation of organelle assembly	biological_process	Any process that activates or increases the frequency, rate or extent of organelle assembly.
GO:1902118	calcidiol binding	molecular_function	Binding to calcidiol.
GO:1902119	regulation of meiotic spindle elongation	biological_process	Any process that modulates the frequency, rate or extent of meiotic spindle elongation.
GO:1902120	negative regulation of meiotic spindle elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.
GO:1902121	lithocholic acid binding	molecular_function	Binding to lithocholic acid.
GO:1902122	chenodeoxycholic acid binding	molecular_function	Binding to chenodeoxycholic acid.
GO:1902123	(-)-pinoresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol.
GO:1902124	(+)-pinoresinol metabolic process	biological_process	The chemical reactions and pathways involving (+)-pinoresinol.
GO:1902125	(+)-pinoresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol.
GO:1902126	(+)-pinoresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-pinoresinol.
GO:1902127	(-)-lariciresinol metabolic process	biological_process	The chemical reactions and pathways involving (-)-lariciresinol.
GO:1902128	(-)-lariciresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.
GO:1902129	(-)-lariciresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-lariciresinol.
GO:1902130	(+)-lariciresinol metabolic process	biological_process	The chemical reactions and pathways involving (+)-lariciresinol.
GO:1902131	(+)-lariciresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol.
GO:1902132	(+)-lariciresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-lariciresinol.
GO:1902133	(+)-secoisolariciresinol metabolic process	biological_process	The chemical reactions and pathways involving (+)-secoisolariciresinol.
GO:1902134	(+)-secoisolariciresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol.
GO:1902135	(+)-secoisolariciresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.
GO:1902136	(-)-secoisolariciresinol metabolic process	biological_process	The chemical reactions and pathways involving (-)-secoisolariciresinol.
GO:1902137	(-)-secoisolariciresinol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol.
GO:1902138	(-)-secoisolariciresinol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol.
GO:1902140	response to inositol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.
GO:1902141	cellular response to inositol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.
GO:1902145	regulation of response to cell cycle checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.
GO:1902146	positive regulation of response to cell cycle checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling.
GO:1902147	regulation of response to cytokinesis checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.
GO:1902148	positive regulation of response to cytokinesis checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.
GO:1902151	regulation of response to DNA integrity checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.
GO:1902152	positive regulation of response to DNA integrity checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.
GO:1902153	regulation of response to DNA damage checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling.
GO:1902154	positive regulation of response to DNA damage checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling.
GO:1902155	regulation of response to G1 DNA damage checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.
GO:1902156	positive regulation of response to G1 DNA damage checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.
GO:1902157	regulation of response to G2 DNA damage checkpoint signaling	biological_process	Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.
GO:1902158	positive regulation of response to G2 DNA damage checkpoint signaling	biological_process	Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.
GO:1902159	regulation of cyclic nucleotide-gated ion channel activity	biological_process	Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
GO:1902160	negative regulation of cyclic nucleotide-gated ion channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	biological_process	Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
GO:1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	biological_process	Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
GO:1902168	response to catechin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.
GO:1902169	cellular response to catechin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.
GO:1902170	cellular response to reactive nitrogen species	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.
GO:1902171	regulation of tocopherol cyclase activity	biological_process	Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.
GO:1902172	regulation of keratinocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.
GO:1902173	negative regulation of keratinocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.
GO:1902174	positive regulation of keratinocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
GO:1902178	fibroblast growth factor receptor apoptotic signaling pathway	biological_process	An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).
GO:1902179	verruculogen metabolic process	biological_process	The chemical reactions and pathways involving verruculogen.
GO:1902181	verruculogen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of verruculogen.
GO:1902182	shoot apical meristem development	biological_process	The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.
GO:1902183	regulation of shoot apical meristem development	biological_process	Any process that modulates the frequency, rate or extent of shoot apical meristem development.
GO:1902184	negative regulation of shoot apical meristem development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.
GO:1902185	positive regulation of shoot apical meristem development	biological_process	Any process that activates or increases the frequency, rate or extent of shoot apical meristem development.
GO:1902189	2-methylbutanoyl-CoA(4-) metabolic process	biological_process	The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-).
GO:1902190	2-methylbutanoyl-CoA(4-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-).
GO:1902191	2-methylbutanoyl-CoA(4-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).
GO:1902192	2-methylbut-2-enoyl-CoA(4-) metabolic process	biological_process	The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).
GO:1902193	2-methylbut-2-enoyl-CoA(4-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-).
GO:1902194	2-methylbut-2-enoyl-CoA(4-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-).
GO:1902195	isovaleryl-CoA(4-) metabolic process	biological_process	The chemical reactions and pathways involving isovaleryl-CoA(4-).
GO:1902196	isovaleryl-CoA(4-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).
GO:1902197	isovaleryl-CoA(4-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-).
GO:1902198	3-methylbut-2-enoyl-CoA(4-) metabolic process	biological_process	The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).
GO:1902199	3-methylbut-2-enoyl-CoA(4-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).
GO:1902200	3-methylbut-2-enoyl-CoA(4-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-).
GO:1902201	negative regulation of bacterial-type flagellum-dependent cell motility	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
GO:1902203	negative regulation of hepatocyte growth factor receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
GO:1902204	positive regulation of hepatocyte growth factor receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
GO:1902205	regulation of interleukin-2-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.
GO:1902206	negative regulation of interleukin-2-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.
GO:1902207	positive regulation of interleukin-2-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.
GO:1902208	regulation of bacterial-type flagellum assembly	biological_process	Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.
GO:1902209	negative regulation of bacterial-type flagellum assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.
GO:1902210	positive regulation of bacterial-type flagellum assembly	biological_process	Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.
GO:1902211	regulation of prolactin signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of prolactin signaling pathway.
GO:1902212	negative regulation of prolactin signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.
GO:1902213	positive regulation of prolactin signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.
GO:1902214	regulation of interleukin-4-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.
GO:1902215	negative regulation of interleukin-4-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.
GO:1902216	positive regulation of interleukin-4-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.
GO:1902217	erythrocyte apoptotic process	biological_process	Any apoptotic process in an erythrocyte.
GO:1902218	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
GO:1902220	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	biological_process	The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
GO:1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
GO:1902224	ketone body metabolic process	biological_process	The chemical reactions and pathways involving ketone body.
GO:1902225	negative regulation of acrosome reaction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.
GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
GO:1902228	positive regulation of macrophage colony-stimulating factor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
GO:1902232	regulation of positive thymic T cell selection	biological_process	Any process that modulates the frequency, rate or extent of positive thymic T cell selection.
GO:1902233	negative regulation of positive thymic T cell selection	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.
GO:1902234	positive regulation of positive thymic T cell selection	biological_process	Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
GO:1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
GO:1902240	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
GO:1902241	copal-8-ol diphosphate(3-) metabolic process	biological_process	The chemical reactions and pathways involving copal-8-ol diphosphate(3-).
GO:1902242	copal-8-ol diphosphate(3-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-).
GO:1902243	copal-8-ol diphosphate(3-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-).
GO:1902244	cis-abienol metabolic process	biological_process	The chemical reactions and pathways involving cis-abienol.
GO:1902245	cis-abienol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cis-abienol.
GO:1902246	cis-abienol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cis-abienol.
GO:1902247	geranylgeranyl diphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.
GO:1902248	5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding	molecular_function	Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.
GO:1902249	IMP binding	molecular_function	Binding to IMP, inosine monophosphate.
GO:1902250	regulation of erythrocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.
GO:1902251	negative regulation of erythrocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.
GO:1902252	positive regulation of erythrocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
GO:1902256	regulation of apoptotic process involved in outflow tract morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
GO:1902258	positive regulation of apoptotic process involved in outflow tract morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
GO:1902259	regulation of delayed rectifier potassium channel activity	biological_process	Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.
GO:1902260	negative regulation of delayed rectifier potassium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.
GO:1902261	positive regulation of delayed rectifier potassium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.
GO:1902262	apoptotic process involved in blood vessel morphogenesis	biological_process	Any apoptotic process that is involved in blood vessel morphogenesis.
GO:1902263	apoptotic process involved in embryonic digit morphogenesis	biological_process	Any apoptotic process that is involved in embryonic digit morphogenesis.
GO:1902265	abscisic acid homeostasis	biological_process	Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.
GO:1902266	intracellular abscisic acid homeostasis	biological_process	A homeostatic process involved in the maintenance of a steady state level of abscisic acid within a cell.
GO:1902267	regulation of polyamine transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.
GO:1902268	negative regulation of polyamine transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.
GO:1902269	positive regulation of polyamine transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.
GO:1902270	(R)-carnitine transmembrane transport	biological_process	The process in which (R)-carnitine is transported across a membrane.
GO:1902271	D3 vitamins binding	molecular_function	Binding to D3 vitamins.
GO:1902272	regulation of (R)-carnitine transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport.
GO:1902273	negative regulation of (R)-carnitine transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport.
GO:1902274	positive regulation of (R)-carnitine transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.
GO:1902275	regulation of chromatin organization	biological_process	Any process that modulates the frequency, rate or extent of chromatin organization.
GO:1902276	regulation of pancreatic amylase secretion	biological_process	Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.
GO:1902277	negative regulation of pancreatic amylase secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.
GO:1902278	positive regulation of pancreatic amylase secretion	biological_process	Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.
GO:1902279	positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway	biological_process	A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.
GO:1902280	regulation of RNA helicase activity	biological_process	Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.
GO:1902281	negative regulation of RNA helicase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity.
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	molecular_function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:1902283	negative regulation of primary amine oxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.
GO:1902284	neuron projection extension involved in neuron projection guidance	biological_process	Any neuron projection extension that is involved in neuron projection guidance.
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	biological_process	Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.
GO:1902286	semaphorin-plexin signaling pathway involved in dendrite guidance	biological_process	Any semaphorin-plexin signaling pathway that is involved in dendrite guidance.
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	biological_process	Any semaphorin-plexin signaling pathway that is involved in axon guidance.
GO:1902288	regulation of defense response to oomycetes	biological_process	Any process that modulates the frequency, rate or extent of defense response to oomycetes.
GO:1902289	negative regulation of defense response to oomycetes	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes.
GO:1902290	positive regulation of defense response to oomycetes	biological_process	Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.
GO:1902291	cell cycle DNA replication DNA ligation	biological_process	Any DNA ligation that is involved in cell cycle DNA replication.
GO:1902292	cell cycle DNA replication initiation	biological_process	Any DNA replication initiation that is involved in cell cycle DNA replication.
GO:1902294	cell cycle DNA replication termination	biological_process	Any DNA replication termination that is involved in cell cycle DNA replication.
GO:1902295	synthesis of RNA primer involved in cell cycle DNA replication	biological_process	Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication.
GO:1902296	DNA strand elongation involved in cell cycle DNA replication	biological_process	Any DNA strand elongation that is involved in cell cycle DNA replication.
GO:1902297	cell cycle DNA replication DNA unwinding	biological_process	Any DNA unwinding that is involved in cell cycle DNA replication.
GO:1902298	cell cycle DNA replication maintenance of fidelity	biological_process	Any maintenance of fidelity that is involved in cell cycle DNA replication.
GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication	biological_process	Any pre-replicative complex assembly that is involved in cell cycle DNA replication.
GO:1902300	galactarate transmembrane transport	biological_process	The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other.
GO:1902301	galactarate transmembrane transporter activity	molecular_function	Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other.
GO:1902305	regulation of sodium ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.
GO:1902306	negative regulation of sodium ion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.
GO:1902307	positive regulation of sodium ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.
GO:1902308	regulation of peptidyl-serine dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation.
GO:1902309	negative regulation of peptidyl-serine dephosphorylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.
GO:1902310	positive regulation of peptidyl-serine dephosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation.
GO:1902311	regulation of copper ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.
GO:1902312	negative regulation of copper ion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport.
GO:1902313	positive regulation of copper ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.
GO:1902314	hydroquinone binding	molecular_function	Binding to hydroquinone.
GO:1902315	nuclear cell cycle DNA replication initiation	biological_process	Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.
GO:1902317	nuclear DNA replication termination	biological_process	Any DNA replication termination that is involved in nuclear cell cycle DNA replication.
GO:1902318	synthesis of RNA primer involved in nuclear cell cycle DNA replication	biological_process	Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication.
GO:1902319	DNA strand elongation involved in nuclear cell cycle DNA replication	biological_process	Any DNA strand elongation that is involved in nuclear cell cycle DNA replication.
GO:1902320	nuclear DNA replication DNA duplex unwinding	biological_process	Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication.
GO:1902321	methyl-branched fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid.
GO:1902322	regulation of methyl-branched fatty acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
GO:1902323	negative regulation of methyl-branched fatty acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
GO:1902324	positive regulation of methyl-branched fatty acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
GO:1902325	negative regulation of chlorophyll biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.
GO:1902326	positive regulation of chlorophyll biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process.
GO:1902327	bacterial-type DNA replication DNA ligation	biological_process	Any DNA ligation that is involved in bacterial-type DNA replication.
GO:1902328	bacterial-type DNA replication initiation	biological_process	Any DNA replication initiation that is involved in bacterial-type DNA replication.
GO:1902329	bacterial-type DNA replication termination	biological_process	Any DNA replication termination that is involved in bacterial-type DNA replication.
GO:1902330	synthesis of RNA primer involved in bacterial-type DNA replication	biological_process	Any synthesis of RNA primer that is involved in bacterial-type DNA replication.
GO:1902332	bacterial-type DNA replication DNA duplex unwinding	biological_process	Any DNA duplex unwinding that is involved in bacterial-type DNA replication.
GO:1902333	nuclear DNA replication DNA ligation	biological_process	Any DNA ligation that is involved in nuclear cell cycle DNA replication.
GO:1902334	fructose export from vacuole to cytoplasm	biological_process	The directed movement of fructose from vacuole to cytoplasm.
GO:1902336	positive regulation of retinal ganglion cell axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.
GO:1902337	regulation of apoptotic process involved in morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.
GO:1902338	negative regulation of apoptotic process involved in morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.
GO:1902339	positive regulation of apoptotic process involved in morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.
GO:1902340	negative regulation of chromosome condensation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.
GO:1902341	xylitol transmembrane transport	biological_process	The directed movement of a xylitol across a membrane. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose.
GO:1902343	regulation of maltose transport	biological_process	Any process that modulates the frequency, rate or extent of maltose transport.
GO:1902344	negative regulation of maltose transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.
GO:1902345	positive regulation of maltose transport	biological_process	Any process that activates or increases the frequency, rate or extent of maltose transport.
GO:1902346	meiotic strand displacement involved in double-strand break repair via SDSA	biological_process	Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA).
GO:1902347	response to strigolactone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.
GO:1902348	cellular response to strigolactone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.
GO:1902349	response to chloroquine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.
GO:1902350	cellular response to chloroquine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.
GO:1902351	response to imidacloprid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus.
GO:1902354	blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment	biological_process	Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment.
GO:1902355	endothelial tube lumen extension involved in blood vessel lumen ensheathment	biological_process	Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment.
GO:1902356	oxaloacetate(2-) transmembrane transport	biological_process	The directed movement of oxaloacetate(2-) across a membrane.
GO:1902357	2-isopropylmalate(2-) transmembrane transport	biological_process	The process in which 2-isopropylmalate(2-) is transported across a membrane.
GO:1902358	sulfate transmembrane transport	biological_process	The directed movement of sulfate across a membrane.
GO:1902359	Notch signaling pathway involved in somitogenesis	biological_process	Any Notch signaling pathway that is involved in somitogenesis.
GO:1902362	melanocyte apoptotic process	biological_process	Any apoptotic process in a melanocyte, the main structural component of the epidermis.
GO:1902363	regulation of protein localization to spindle pole body	biological_process	Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.
GO:1902364	negative regulation of protein localization to spindle pole body	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.
GO:1902365	positive regulation of protein localization to spindle pole body	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.
GO:1902366	regulation of Notch signaling pathway involved in somitogenesis	biological_process	Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.
GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.
GO:1902369	negative regulation of RNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.
GO:1902370	regulation of tRNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of tRNA catabolic process.
GO:1902371	negative regulation of tRNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.
GO:1902372	positive regulation of tRNA catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.
GO:1902373	negative regulation of mRNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.
GO:1902374	regulation of rRNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of rRNA catabolic process.
GO:1902378	VEGF-activated neuropilin signaling pathway involved in axon guidance	biological_process	Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance.
GO:1902379	chemoattractant activity involved in axon guidance	molecular_function	Any chemoattractant activity that is involved in axon guidance.
GO:1902380	positive regulation of endoribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.
GO:1902381	11-oxo-beta-amyrin metabolic process	biological_process	The chemical reactions and pathways involving 11-oxo-beta-amyrin.
GO:1902382	11-oxo-beta-amyrin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.
GO:1902383	11-oxo-beta-amyrin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin.
GO:1902384	glycyrrhetinate metabolic process	biological_process	The chemical reactions and pathways involving glycyrrhetinate.
GO:1902385	glycyrrhetinate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.
GO:1902386	glycyrrhetinate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glycyrrhetinate.
GO:1902387	ceramide 1-phosphate binding	molecular_function	Binding to ceramide 1-phosphate.
GO:1902388	ceramide 1-phosphate transfer activity	molecular_function	Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:1902389	ceramide 1-phosphate transport	biological_process	The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1902390	regulation of N-terminal peptidyl-serine acetylation	biological_process	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation.
GO:1902391	positive regulation of N-terminal peptidyl-serine acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation.
GO:1902392	regulation of exodeoxyribonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.
GO:1902393	negative regulation of exodeoxyribonuclease activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.
GO:1902394	positive regulation of exodeoxyribonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity.
GO:1902395	regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity	biological_process	Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity.
GO:1902396	protein localization to bicellular tight junction	biological_process	A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.
GO:1902404	mitotic actomyosin contractile ring contraction	biological_process	Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.
GO:1902406	mitotic actomyosin contractile ring maturation	biological_process	The cellular process in which the mitotic contractile ring cytokinetic ring attains its fully functional state.
GO:1902407	assembly of actomyosin apparatus involved in mitotic cytokinesis	biological_process	Any assembly of mitotic cytokinetic actomyosin apparatus.
GO:1902408	mitotic cytokinesis, division site positioning	biological_process	The process in which a contractile ring is positioned in a specific location during the mitotic cell cycle. This process is critical for both for both symmetric and asymmetric cell divisions.
GO:1902410	mitotic cytokinetic process	biological_process	Any cytokinetic process that is involved in mitotic cell cycle.
GO:1902412	regulation of mitotic cytokinesis	biological_process	Any process that modulates the frequency, rate or extent of mitotic cytokinesis.
GO:1902413	negative regulation of mitotic cytokinesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.
GO:1902414	protein localization to cell junction	biological_process	A process in which a protein is transported to, or maintained in, a location within a cell junction.
GO:1902415	regulation of mRNA binding	biological_process	Any process that modulates the frequency, rate or extent of mRNA binding.
GO:1902416	positive regulation of mRNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA binding.
GO:1902417	(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity	molecular_function	Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.
GO:1902418	(+)-abscisic acid D-glucopyranosyl ester transmembrane transport	biological_process	The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane.
GO:1902421	hydrogen metabolic process	biological_process	The chemical reactions and pathways involving H2 (dihydrogen).
GO:1902422	hydrogen biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).
GO:1902423	regulation of attachment of mitotic spindle microtubules to kinetochore	biological_process	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
GO:1902424	negative regulation of attachment of mitotic spindle microtubules to kinetochore	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
GO:1902426	deactivation of mitotic spindle assembly checkpoint	biological_process	A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
GO:1902427	regulation of water channel activity	biological_process	Any process that modulates the frequency, rate or extent of water channel activity.
GO:1902428	negative regulation of water channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity.
GO:1902429	positive regulation of water channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of water channel activity.
GO:1902430	negative regulation of amyloid-beta formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.
GO:1902432	protein localization to division septum	biological_process	A process in which a protein is transported to, or maintained in, a location within a division septum.
GO:1902433	positive regulation of water channel activity involved in maintenance of lens transparency	biological_process	Any positive regulation of water channel activity that is involved in maintenance of lens transparency.
GO:1902434	sulfate import across plasma membrane	biological_process	The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.
GO:1902435	regulation of male mating behavior	biological_process	Any process that modulates the frequency, rate or extent of male mating behavior.
GO:1902436	negative regulation of male mating behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.
GO:1902437	positive regulation of male mating behavior	biological_process	Any process that activates or increases the frequency, rate or extent of male mating behavior.
GO:1902438	response to vanadate(3-)	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.
GO:1902439	cellular response to vanadate(3-)	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.
GO:1902440	protein localization to mitotic spindle pole body	biological_process	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.
GO:1902441	protein localization to meiotic spindle pole body	biological_process	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.
GO:1902442	regulation of ripoptosome assembly involved in necroptotic process	biological_process	Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.
GO:1902443	negative regulation of ripoptosome assembly involved in necroptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.
GO:1902444	riboflavin binding	molecular_function	Binding to riboflavin.
GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	biological_process	Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.
GO:1902446	regulation of shade avoidance	biological_process	Any process that modulates the frequency, rate or extent of shade avoidance.
GO:1902447	negative regulation of shade avoidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance.
GO:1902448	positive regulation of shade avoidance	biological_process	Any process that activates or increases the frequency, rate or extent of shade avoidance.
GO:1902455	negative regulation of stem cell population maintenance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.
GO:1902456	regulation of stomatal opening	biological_process	Any process that modulates the frequency, rate or extent of stomatal opening.
GO:1902457	negative regulation of stomatal opening	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening.
GO:1902458	positive regulation of stomatal opening	biological_process	Any process that activates or increases the frequency, rate or extent of stomatal opening.
GO:1902459	positive regulation of stem cell population maintenance	biological_process	Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
GO:1902460	regulation of mesenchymal stem cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.
GO:1902461	negative regulation of mesenchymal stem cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.
GO:1902462	positive regulation of mesenchymal stem cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.
GO:1902463	protein localization to cell leading edge	biological_process	A process in which a protein is transported to, or maintained in, a location within a cell leading edge.
GO:1902464	regulation of histone H3-K27 trimethylation	biological_process	Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation.
GO:1902465	negative regulation of histone H3-K27 trimethylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation.
GO:1902466	positive regulation of histone H3-K27 trimethylation	biological_process	Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation.
GO:1902472	regulation of mitotic cytokinesis, division site positioning	biological_process	Any process that modulates the frequency, rate or extent of mitotic cytokinesis, division site positioning.
GO:1902473	regulation of protein localization to synapse	biological_process	Any process that modulates the frequency, rate or extent of protein localization to synapse.
GO:1902474	positive regulation of protein localization to synapse	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to synapse.
GO:1902475	L-alpha-amino acid transmembrane transport	biological_process	The directed movement of L-alpha-amino acid across a membrane.
GO:1902476	chloride transmembrane transport	biological_process	The process in which chloride is transported across a membrane.
GO:1902480	protein localization to mitotic spindle	biological_process	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.
GO:1902481	gamma-tubulin complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.
GO:1902482	regulatory T cell apoptotic process	biological_process	Any apoptotic process in a regulatory T cell.
GO:1902483	cytotoxic T cell pyroptotic process	biological_process	Any pyroptotic process in a cytotoxic T cell.
GO:1902484	Sertoli cell apoptotic process	biological_process	Any apoptotic process in a Sertoli cell.
GO:1902485	L-cysteine binding	molecular_function	Binding to L-cysteine.
GO:1902486	protein localization to growing cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location within a growing cell tip.
GO:1902487	protein localization to non-growing cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.
GO:1902488	cholangiocyte apoptotic process	biological_process	Any apoptotic process in a cholangiocyte.
GO:1902489	hepatoblast apoptotic process	biological_process	Any apoptotic process in a hepatoblast.
GO:1902490	regulation of sperm capacitation	biological_process	Any process that modulates the frequency, rate or extent of sperm capacitation.
GO:1902491	negative regulation of sperm capacitation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.
GO:1902492	positive regulation of sperm capacitation	biological_process	Any process that activates or increases the frequency, rate or extent of sperm capacitation.
GO:1902493	acetyltransferase complex	cellular_component	A protein complex which is capable of acetyltransferase activity.
GO:1902494	catalytic complex	cellular_component	A protein complex which is capable of catalytic activity.
GO:1902495	transmembrane transporter complex	cellular_component	A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
GO:1902497	iron-sulfur cluster transmembrane transport	biological_process	A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:1902498	regulation of protein autoubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein autoubiquitination.
GO:1902499	positive regulation of protein autoubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.
GO:1902500	vacuolar HOPS complex	cellular_component	Any HOPS complex that is part of a vacuolar membrane.
GO:1902501	lysosomal HOPS complex	cellular_component	Any HOPS complex that is part of a lysosomal membrane.
GO:1902502	multivesicular body HOPS complex	cellular_component	Any HOPS complex that is part of a multivesicular body membrane.
GO:1902503	adenylyltransferase complex	cellular_component	A protein complex which is capable of adenylyltransferase activity.
GO:1902507	thiazole synthase complex	cellular_component	A protein complex which is capable of thiazole synthase activity.
GO:1902508	2-iminoacetate synthase complex	cellular_component	A protein complex which is capable of 2-iminoacetate synthase activity.
GO:1902509	methionine-importing complex	cellular_component	A protein complex which is capable of methionine-importing activity.
GO:1902510	regulation of apoptotic DNA fragmentation	biological_process	Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.
GO:1902511	negative regulation of apoptotic DNA fragmentation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.
GO:1902512	positive regulation of apoptotic DNA fragmentation	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.
GO:1902513	regulation of organelle transport along microtubule	biological_process	Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	biological_process	Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.
GO:1902515	thioredoxin-disulfide reductase complex	cellular_component	A protein complex which is capable of thioredoxin-disulfide reductase activity.
GO:1902516	sn-glycerol 3-phosphate binding	molecular_function	Binding to sn-glycerol 3-phosphate.
GO:1902517	glycerol-3-phosphate-transporting ATPase complex	cellular_component	A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity.
GO:1902518	response to cyclophosphamide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
GO:1902519	response to docetaxel trihydrate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
GO:1902520	response to doxorubicin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
GO:1902521	response to etoposide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
GO:1902522	response to 4'-epidoxorubicin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
GO:1902523	positive regulation of protein K63-linked ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.
GO:1902524	positive regulation of protein K48-linked ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.
GO:1902525	regulation of protein monoubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein monoubiquitination.
GO:1902526	negative regulation of protein monoubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination.
GO:1902527	positive regulation of protein monoubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
GO:1902528	regulation of protein linear polyubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.
GO:1902529	negative regulation of protein linear polyubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination.
GO:1902530	positive regulation of protein linear polyubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.
GO:1902531	regulation of intracellular signal transduction	biological_process	Any process that modulates the frequency, rate or extent of intracellular signal transduction.
GO:1902532	negative regulation of intracellular signal transduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
GO:1902533	positive regulation of intracellular signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
GO:1902542	regulation of protein localization to mitotic spindle pole body	biological_process	Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.
GO:1902543	negative regulation of protein localization to mitotic spindle pole body	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.
GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.
GO:1902549	protein localization to Mei2 nuclear dot	biological_process	A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.
GO:1902550	lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis	biological_process	Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis.
GO:1902551	regulation of catalase activity	biological_process	Any process that modulates the frequency, rate or extent of catalase activity.
GO:1902552	negative regulation of catalase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity.
GO:1902553	positive regulation of catalase activity	biological_process	Any process that activates or increases the frequency, rate or extent of catalase activity.
GO:1902554	serine/threonine protein kinase complex	cellular_component	A protein complex which is capable of protein serine/threonine kinase activity.
GO:1902555	endoribonuclease complex	cellular_component	A protein complex which is capable of endoribonuclease activity.
GO:1902556	phosphatidylinositol transporter complex	cellular_component	A protein complex which is capable of phosphatidylinositol transporter activity.
GO:1902557	5'-adenylyl sulfate transmembrane transporter activity	molecular_function	Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.
GO:1902558	5'-adenylyl sulfate transmembrane transport	biological_process	The process in which 5'-adenylyl sulfate is transported across a membrane.
GO:1902559	3'-phospho-5'-adenylyl sulfate transmembrane transport	biological_process	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane.
GO:1902560	GMP reductase complex	cellular_component	An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H+ + NADPH => IMP + NADP+ + NH4.
GO:1902561	origin recognition complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex.
GO:1902562	H4 histone acetyltransferase complex	cellular_component	A protein complex which is capable of H4 histone acetyltransferase activity.
GO:1902563	regulation of neutrophil activation	biological_process	Any process that modulates the frequency, rate or extent of neutrophil activation.
GO:1902564	negative regulation of neutrophil activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.
GO:1902565	positive regulation of neutrophil activation	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil activation.
GO:1902566	regulation of eosinophil activation	biological_process	Any process that modulates the frequency, rate or extent of eosinophil activation.
GO:1902567	negative regulation of eosinophil activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.
GO:1902568	positive regulation of eosinophil activation	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil activation.
GO:1902569	negative regulation of activation of Janus kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity.
GO:1902570	protein localization to nucleolus	biological_process	A process in which a protein is transported to, or maintained in, a location within a nucleolus.
GO:1902571	regulation of serine-type peptidase activity	biological_process	Any process that modulates the frequency, rate or extent of serine-type peptidase activity.
GO:1902572	negative regulation of serine-type peptidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity.
GO:1902573	positive regulation of serine-type peptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity.
GO:1902575	protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly	biological_process	Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly.
GO:1902576	negative regulation of nuclear cell cycle DNA replication	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.
GO:1902577	protein localization to medial cortical node	biological_process	A process in which a protein is transported to, or maintained in, a location within a medial cortical node.
GO:1902584	positive regulation of response to water deprivation	biological_process	Any process that activates or increases the frequency, rate or extent of response to water deprivation.
GO:1902595	regulation of DNA replication origin binding	biological_process	Any process that modulates the frequency, rate or extent of DNA replication origin binding.
GO:1902596	negative regulation of DNA replication origin binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.
GO:1902597	positive regulation of DNA replication origin binding	biological_process	Any process that activates or increases the frequency, rate or extent of DNA replication origin binding.
GO:1902599	sulfathiazole transmembrane transport	biological_process	The directed movement of sulfathiazole across a membrane.
GO:1902600	proton transmembrane transport	biological_process	The directed movement of a proton across a membrane.
GO:1902601	silver ion transmembrane transport	biological_process	The directed movement of silver ion across a membrane.
GO:1902602	aluminum ion transmembrane transport	biological_process	The process in which an aluminium ion is transported across a membrane.
GO:1902603	carnitine transmembrane transport	biological_process	The directed movement of carnitine across a membrane.
GO:1902604	p-aminobenzoyl-glutamate transmembrane transport	biological_process	The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane.
GO:1902605	heterotrimeric G-protein complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.
GO:1902606	regulation of large conductance calcium-activated potassium channel activity	biological_process	Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
GO:1902607	negative regulation of large conductance calcium-activated potassium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
GO:1902609	(R)-2-hydroxy-alpha-linolenic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid.
GO:1902610	response to N-phenylthiourea	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.
GO:1902611	cellular response to N-phenylthiourea	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.
GO:1902612	regulation of anti-Mullerian hormone signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
GO:1902613	negative regulation of anti-Mullerian hormone signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
GO:1902614	positive regulation of anti-Mullerian hormone signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
GO:1902615	immune response involved in response to exogenous dsRNA	biological_process	Any immune response that is involved in response to exogenous dsRNA.
GO:1902616	acyl carnitine transmembrane transport	biological_process	The process in which acyl carnitine is transported across a membrane.
GO:1902617	response to fluoride	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
GO:1902618	cellular response to fluoride	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
GO:1902619	regulation of microtubule minus-end binding	biological_process	Any process that modulates the frequency, rate or extent of microtubule minus-end binding.
GO:1902620	positive regulation of microtubule minus-end binding	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.
GO:1902621	actomyosin contractile ring disassembly	biological_process	The disaggregation of an actomyosin contractile ring into its constituent components.
GO:1902622	regulation of neutrophil migration	biological_process	Any process that modulates the frequency, rate or extent of neutrophil migration.
GO:1902623	negative regulation of neutrophil migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.
GO:1902624	positive regulation of neutrophil migration	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil migration.
GO:1902626	assembly of large subunit precursor of preribosome	biological_process	The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.
GO:1902627	regulation of assembly of large subunit precursor of preribosome	biological_process	Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.
GO:1902628	positive regulation of assembly of large subunit precursor of preribosome	biological_process	Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome.
GO:1902629	regulation of mRNA stability involved in cellular response to UV	biological_process	Any regulation of mRNA stability that is involved in cellular response to UV.
GO:1902630	regulation of membrane hyperpolarization	biological_process	Any process that modulates the frequency, rate or extent of membrane hyperpolarization.
GO:1902631	negative regulation of membrane hyperpolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.
GO:1902632	positive regulation of membrane hyperpolarization	biological_process	Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.
GO:1902633	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:1902634	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:1902635	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
GO:1902636	kinociliary basal body	cellular_component	A ciliary basal body that is part of a kinocilium.
GO:1902637	neural crest cell differentiation involved in thymus development	biological_process	Any neural crest cell differentiation that is involved in thymus development.
GO:1902638	neural crest cell differentiation involved in parathyroid gland development	biological_process	Any neural crest cell differentiation that is involved in parathyroid gland development.
GO:1902639	propan-2-ol metabolic process	biological_process	The chemical reactions and pathways involving propan-2-ol.
GO:1902640	propan-2-ol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of propan-2-ol.
GO:1902641	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	biological_process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
GO:1902642	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
GO:1902643	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
GO:1902644	tertiary alcohol metabolic process	biological_process	The chemical reactions and pathways involving tertiary alcohol.
GO:1902645	tertiary alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of tertiary alcohol.
GO:1902646	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
GO:1902647	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
GO:1902648	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
GO:1902652	secondary alcohol metabolic process	biological_process	The chemical reactions and pathways involving secondary alcohol.
GO:1902653	secondary alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of secondary alcohol.
GO:1902654	aromatic primary alcohol metabolic process	biological_process	The chemical reactions and pathways involving aromatic primary alcohol.
GO:1902655	aromatic primary alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.
GO:1902656	calcium ion import into cytosol	biological_process	The directed movement of calcium ion into a cytosol.
GO:1902657	protein localization to prospore membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a prospore membrane.
GO:1902659	regulation of glucose mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway.
GO:1902660	negative regulation of glucose mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.
GO:1902661	positive regulation of glucose mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.
GO:1902662	regulation of peptidyl-L-cysteine S-palmitoylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
GO:1902663	negative regulation of peptidyl-L-cysteine S-palmitoylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
GO:1902664	positive regulation of peptidyl-L-cysteine S-palmitoylation	biological_process	Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
GO:1902665	response to isobutanol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus.
GO:1902667	regulation of axon guidance	biological_process	Any process that modulates the frequency, rate or extent of axon guidance.
GO:1902668	negative regulation of axon guidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance.
GO:1902669	positive regulation of axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of axon guidance.
GO:1902670	carbon dioxide binding	molecular_function	Binding to carbon dioxide.
GO:1902671	left anterior basal body	cellular_component	Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).
GO:1902672	right anterior basal body	cellular_component	Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage).
GO:1902673	left posteriolateral basal body	cellular_component	Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage).
GO:1902674	right posteriolateral basal body	cellular_component	Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage).
GO:1902675	left ventral basal body	cellular_component	Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).
GO:1902676	right ventral basal body	cellular_component	Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage).
GO:1902677	left caudal basal body	cellular_component	Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage).
GO:1902678	right caudal basal body	cellular_component	Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).
GO:1902679	negative regulation of RNA biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
GO:1902680	positive regulation of RNA biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
GO:1902681	regulation of replication fork arrest at rDNA repeats	biological_process	Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.
GO:1902682	protein localization to pericentric heterochromatin	biological_process	A process in which a protein is transported to, or maintained in the pericentric heterochromatin.
GO:1902683	regulation of receptor localization to synapse	biological_process	Any process that modulates the frequency, rate or extent of receptor localization to synapse.
GO:1902684	negative regulation of receptor localization to synapse	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.
GO:1902685	positive regulation of receptor localization to synapse	biological_process	Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	biological_process	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.
GO:1902687	glucosidase complex	cellular_component	A protein complex which is capable of glucosidase activity.
GO:1902688	regulation of NAD metabolic process	biological_process	Any process that modulates the frequency, rate or extent of NAD metabolic process.
GO:1902689	negative regulation of NAD metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.
GO:1902690	positive regulation of NAD metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of NAD metabolic process.
GO:1902691	respiratory basal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.
GO:1902692	regulation of neuroblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of neuroblast proliferation.
GO:1902693	superoxide dismutase complex	cellular_component	A protein complex which is capable of superoxide dismutase activity.
GO:1902694	superoxide dismutase copper chaperone complex	cellular_component	A protein complex which is capable of superoxide dismutase copper chaperone activity.
GO:1902695	metallochaperone complex	cellular_component	A protein complex which is capable of metallochaperone activity.
GO:1902696	glycine catabolic process to isobutanol	biological_process	The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol.
GO:1902697	valine catabolic process to isobutanol	biological_process	The chemical reactions and pathways resulting in the breakdown of valine to isobutanol.
GO:1902698	pentose catabolic process to butyrate	biological_process	The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.
GO:1902699	pentose catabolic process to acetate	biological_process	The chemical reactions and pathways resulting in the breakdown of pentose to acetate.
GO:1902700	pentose catabolic process to butan-1-ol	biological_process	The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol.
GO:1902701	pentose catabolic process to propan-2-ol	biological_process	The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol.
GO:1902708	response to plumbagin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.
GO:1902709	cellular response to plumbagin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.
GO:1902710	GABA receptor complex	cellular_component	A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.
GO:1902711	GABA-A receptor complex	cellular_component	A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor).
GO:1902712	G protein-coupled GABA receptor complex	cellular_component	A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2.
GO:1902716	cell cortex of growing cell tip	cellular_component	Any cell cortex that is part of a growing cell tip.
GO:1902721	negative regulation of prolactin secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.
GO:1902722	positive regulation of prolactin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of prolactin secretion.
GO:1902723	negative regulation of skeletal muscle satellite cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.
GO:1902724	positive regulation of skeletal muscle satellite cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.
GO:1902725	negative regulation of satellite cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.
GO:1902726	positive regulation of skeletal muscle satellite cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of satellite cell differentiation.
GO:1902727	negative regulation of growth factor dependent skeletal muscle satellite cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
GO:1902728	positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
GO:1902729	negative regulation of proteoglycan biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:1902730	positive regulation of proteoglycan biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
GO:1902731	negative regulation of chondrocyte proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
GO:1902732	positive regulation of chondrocyte proliferation	biological_process	Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
GO:1902733	regulation of growth plate cartilage chondrocyte differentiation	biological_process	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
GO:1902734	regulation of receptor-mediated virion attachment to host cell	biological_process	Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell.
GO:1902735	negative regulation of receptor-mediated virion attachment to host cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell.
GO:1902736	positive regulation of receptor-mediated virion attachment to host cell	biological_process	Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.
GO:1902737	dendritic filopodium	cellular_component	A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.
GO:1902738	regulation of chondrocyte differentiation involved in endochondral bone morphogenesis	biological_process	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
GO:1902742	apoptotic process involved in development	biological_process	Any apoptotic process that is involved in anatomical structure development.
GO:1902743	regulation of lamellipodium organization	biological_process	Any process that modulates the frequency, rate or extent of lamellipodium organization.
GO:1902744	negative regulation of lamellipodium organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization.
GO:1902745	positive regulation of lamellipodium organization	biological_process	Any process that activates or increases the frequency, rate or extent of lamellipodium organization.
GO:1902746	regulation of lens fiber cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.
GO:1902747	negative regulation of lens fiber cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.
GO:1902748	positive regulation of lens fiber cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.
GO:1902749	regulation of cell cycle G2/M phase transition	biological_process	Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.
GO:1902750	negative regulation of cell cycle G2/M phase transition	biological_process	Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.
GO:1902751	positive regulation of cell cycle G2/M phase transition	biological_process	Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.
GO:1902752	regulation of renal amino acid absorption	biological_process	Any process that modulates the frequency, rate or extent of renal amino acid absorption.
GO:1902753	negative regulation of renal amino acid absorption	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption.
GO:1902754	positive regulation of renal amino acid absorption	biological_process	Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.
GO:1902755	sulfurated eukaryotic molybdenum cofactor(2-) metabolic process	biological_process	The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-).
GO:1902756	sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).
GO:1902757	bis(molybdopterin guanine dinucleotide)molybdenum metabolic process	biological_process	The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum.
GO:1902758	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum.
GO:1902759	Mo(VI)-molybdopterin cytosine dinucleotide metabolic process	biological_process	The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide.
GO:1902760	Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide.
GO:1902761	positive regulation of chondrocyte development	biological_process	Any process that activates or increases the frequency, rate or extent of chondrocyte development.
GO:1902762	regulation of embryonic skeletal joint development	biological_process	Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.
GO:1902763	negative regulation of embryonic skeletal joint development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development.
GO:1902764	positive regulation of embryonic skeletal joint development	biological_process	Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.
GO:1902766	skeletal muscle satellite cell migration	biological_process	The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.
GO:1902767	isoprenoid biosynthetic process via mevalonate	biological_process	The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.
GO:1902768	isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate	biological_process	The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.
GO:1902769	regulation of choline O-acetyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity.
GO:1902770	negative regulation of choline O-acetyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.
GO:1902771	positive regulation of choline O-acetyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.
GO:1902772	positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway	biological_process	Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway.
GO:1902773	GTPase activator complex	cellular_component	A protein complex which is capable of GTPase activator activity.
GO:1902774	late endosome to lysosome transport	biological_process	The directed movement of substances from late endosome to lysosome.
GO:1902775	mitochondrial large ribosomal subunit assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.
GO:1902776	6-sulfoquinovose(1-) metabolic process	biological_process	The chemical reactions and pathways involving 6-sulfoquinovose(1-).
GO:1902777	6-sulfoquinovose(1-) catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).
GO:1902778	response to alkane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.
GO:1902779	cellular response to alkane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.
GO:1902780	response to nonane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.
GO:1902781	cellular response to nonane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.
GO:1902782	response to decane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.
GO:1902783	cellular response to decane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.
GO:1902784	response to undecane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.
GO:1902785	cellular response to undecane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.
GO:1902786	response to dodecane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.
GO:1902787	cellular response to dodecane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.
GO:1902788	response to isooctane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.
GO:1902789	cellular response to isooctane	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.
GO:1902790	undecan-2-one metabolic process	biological_process	The chemical reactions and pathways involving undecan-2-one.
GO:1902791	undecan-2-one biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of undecan-2-one.
GO:1902792	pyrroline-5-carboxylate reductase complex	cellular_component	A protein complex which is capable of pyrroline-5-carboxylate reductase activity.
GO:1902793	glutamate decarboxylase complex	cellular_component	A protein complex which is capable of glutamate decarboxylase activity.
GO:1902794	siRNA-independent facultative heterochromatin formation	biological_process	The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs.
GO:1902795	siRNA-mediated facultative heterochromatin formation	biological_process	The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA.
GO:1902796	regulation of snoRNA processing	biological_process	Any process that modulates the frequency, rate or extent of snoRNA processing.
GO:1902797	negative regulation of snoRNA processing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.
GO:1902798	positive regulation of snoRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of snoRNA processing.
GO:1902799	regulation of phosphodiesterase I activity	biological_process	Any process that modulates the frequency, rate or extent of phosphodiesterase I activity.
GO:1902800	positive regulation of phosphodiesterase I activity	biological_process	Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.
GO:1902801	regulation of siRNA-independent facultative heterochromatin formation	biological_process	Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly.
GO:1902802	regulation of siRNA-dependent facultative heterochromatin formation	biological_process	Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation.
GO:1902803	regulation of synaptic vesicle transport	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle transport.
GO:1902804	negative regulation of synaptic vesicle transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport.
GO:1902805	positive regulation of synaptic vesicle transport	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.
GO:1902806	regulation of cell cycle G1/S phase transition	biological_process	Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
GO:1902807	negative regulation of cell cycle G1/S phase transition	biological_process	Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
GO:1902808	positive regulation of cell cycle G1/S phase transition	biological_process	Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
GO:1902809	regulation of skeletal muscle fiber differentiation	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.
GO:1902810	negative regulation of skeletal muscle fiber differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.
GO:1902811	positive regulation of skeletal muscle fiber differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.
GO:1902815	N,N'-diacetylchitobiose import	biological_process	The directed movement of N,N'-diacetylchitobiose into a cell or organelle.
GO:1902816	regulation of protein localization to microtubule	biological_process	Any process that modulates the frequency, rate or extent of protein localization to microtubule.
GO:1902817	negative regulation of protein localization to microtubule	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.
GO:1902818	ethyl acetate metabolic process	biological_process	The chemical reactions and pathways involving ethyl acetate.
GO:1902819	ethyl acetate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ethyl acetate.
GO:1902820	1-undecene metabolic process	biological_process	The chemical reactions and pathways involving 1-undecene.
GO:1902821	1-undecene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-undecene.
GO:1902822	regulation of late endosome to lysosome transport	biological_process	Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.
GO:1902823	negative regulation of late endosome to lysosome transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.
GO:1902824	positive regulation of late endosome to lysosome transport	biological_process	Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.
GO:1902829	regulation of spinal cord association neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.
GO:1902830	negative regulation of spinal cord association neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.
GO:1902831	positive regulation of spinal cord association neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.
GO:1902832	negative regulation of cell proliferation in dorsal spinal cord	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.
GO:1902833	positive regulation of cell proliferation in dorsal spinal cord	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.
GO:1902834	regulation of proline import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of proline import into cell.
GO:1902835	negative regulation of proline import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell.
GO:1902836	positive regulation of proline import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of proline import into cell.
GO:1902838	regulation of nuclear migration along microtubule	biological_process	Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.
GO:1902839	negative regulation of nuclear migration along microtubule	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.
GO:1902840	positive regulation of nuclear migration along microtubule	biological_process	Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.
GO:1902841	regulation of netrin-activated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.
GO:1902842	negative regulation of netrin-activated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.
GO:1902843	positive regulation of netrin-activated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.
GO:1902844	positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway	biological_process	A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation.
GO:1902845	negative regulation of mitotic spindle elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.
GO:1902846	positive regulation of mitotic spindle elongation	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.
GO:1902847	regulation of neuronal signal transduction	biological_process	Any process that modulates the frequency, rate or extent of neuronal signal transduction.
GO:1902848	negative regulation of neuronal signal transduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.
GO:1902849	positive regulation of neuronal signal transduction	biological_process	Any process that activates or increases the frequency, rate or extent of neuronal signal transduction.
GO:1902850	microtubule cytoskeleton organization involved in mitosis	biological_process	Any microtubule cytoskeleton organization that is involved in mitosis.
GO:1902852	regulation of nuclear migration during mitotic telophase	biological_process	Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.
GO:1902853	negative regulation of nuclear migration during mitotic telophase	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.
GO:1902854	positive regulation of nuclear migration during mitotic telophase	biological_process	Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.
GO:1902855	regulation of non-motile cilium assembly	biological_process	Any process that modulates the frequency, rate or extent of non-motile cilium assembly.
GO:1902856	negative regulation of non-motile cilium assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.
GO:1902857	positive regulation of non-motile cilium assembly	biological_process	Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
GO:1902858	propionyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving propionyl-CoA.
GO:1902859	propionyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of propionyl-CoA.
GO:1902860	propionyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of propionyl-CoA.
GO:1902863	regulation of embryonic camera-type eye development	biological_process	Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.
GO:1902864	negative regulation of embryonic camera-type eye development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.
GO:1902865	positive regulation of embryonic camera-type eye development	biological_process	Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.
GO:1902866	regulation of retina development in camera-type eye	biological_process	Any process that modulates the frequency, rate or extent of retina development in camera-type eye.
GO:1902867	negative regulation of retina development in camera-type eye	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.
GO:1902868	positive regulation of retina development in camera-type eye	biological_process	Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.
GO:1902869	regulation of amacrine cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of amacrine cell differentiation.
GO:1902870	negative regulation of amacrine cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.
GO:1902871	positive regulation of amacrine cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.
GO:1902872	regulation of horizontal cell localization	biological_process	Any process that modulates the frequency, rate or extent of horizontal cell localization.
GO:1902873	negative regulation of horizontal cell localization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.
GO:1902874	positive regulation of horizontal cell localization	biological_process	Any process that activates or increases the frequency, rate or extent of horizontal cell localization.
GO:1902875	regulation of embryonic pattern specification	biological_process	Any process that modulates the frequency, rate or extent of embryonic pattern specification.
GO:1902876	negative regulation of embryonic pattern specification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.
GO:1902877	positive regulation of embryonic pattern specification	biological_process	Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.
GO:1902882	regulation of response to oxidative stress	biological_process	Any process that modulates the frequency, rate or extent of response to oxidative stress.
GO:1902883	negative regulation of response to oxidative stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.
GO:1902884	positive regulation of response to oxidative stress	biological_process	Any process that activates or increases the frequency, rate or extent of response to oxidative stress.
GO:1902888	protein localization to astral microtubule	biological_process	A process in which a protein is transported to, or maintained in, a location within an astral microtubule.
GO:1902889	protein localization to spindle microtubule	biological_process	A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.
GO:1902890	regulation of root hair elongation	biological_process	Any process that modulates the frequency, rate or extent of root hair elongation.
GO:1902891	negative regulation of root hair elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.
GO:1902892	positive regulation of root hair elongation	biological_process	Any process that activates or increases the frequency, rate or extent of root hair elongation.
GO:1902893	regulation of miRNA transcription	biological_process	Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription.
GO:1902894	negative regulation of miRNA transcription	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microRNA (miRNA) gene transcription.
GO:1902895	positive regulation of miRNA transcription	biological_process	Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription.
GO:1902896	terminal web assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a terminal web.
GO:1902897	regulation of postsynaptic density protein 95 clustering	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.
GO:1902898	fatty acid methyl ester metabolic process	biological_process	The chemical reactions and pathways involving fatty acid methyl ester.
GO:1902899	fatty acid methyl ester biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fatty acid methyl ester.
GO:1902900	gut granule assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a gut granule.
GO:1902902	negative regulation of autophagosome assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.
GO:1902903	regulation of supramolecular fiber organization	biological_process	Any process that modulates the frequency, rate or extent of supramolecular fiber organization.
GO:1902904	negative regulation of supramolecular fiber organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
GO:1902905	positive regulation of supramolecular fiber organization	biological_process	Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.
GO:1902906	proteasome storage granule assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.
GO:1902907	proteasome storage granule disassembly	biological_process	The disaggregation of a proteasome storage granule into its constituent components.
GO:1902908	regulation of melanosome transport	biological_process	Any process that modulates the frequency, rate or extent of melanosome transport.
GO:1902909	negative regulation of melanosome transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.
GO:1902910	positive regulation of melanosome transport	biological_process	Any process that activates or increases the frequency, rate or extent of melanosome transport.
GO:1902911	protein kinase complex	cellular_component	A protein complex which is capable of protein kinase activity.
GO:1902912	pyruvate kinase complex	cellular_component	A protein complex which is capable of pyruvate kinase activity.
GO:1902913	positive regulation of neuroepithelial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.
GO:1902914	regulation of protein polyubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein polyubiquitination.
GO:1902915	negative regulation of protein polyubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.
GO:1902916	positive regulation of protein polyubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.
GO:1902917	positive regulation of mating projection assembly	biological_process	Any process that activates or increases the frequency, rate or extent of mating projection assembly.
GO:1902918	poly(5-hydroxyvalerate) metabolic process	biological_process	The chemical reactions and pathways involving poly(5-hydroxyvalerate).
GO:1902919	poly(5-hydroxyvalerate) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).
GO:1902920	poly(hydroxyvalerate) metabolic process	biological_process	The chemical reactions and pathways involving poly(hydroxyvalerate).
GO:1902921	poly(hydroxyvalerate) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).
GO:1902922	poly(3-hydroxyvalerate) metabolic process	biological_process	The chemical reactions and pathways involving poly(3-hydroxyvalerate).
GO:1902923	poly(3-hydroxyvalerate) biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).
GO:1902924	poly(hydroxyalkanoate) biosynthetic process from glucose	biological_process	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose.
GO:1902925	poly(hydroxyalkanoate) biosynthetic process from fatty acid	biological_process	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid.
GO:1902926	inulin metabolic process	biological_process	The chemical reactions and pathways involving inulin.
GO:1902927	inulin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of inulin.
GO:1902928	inulin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of inulin.
GO:1902929	plasma membrane of growing cell tip	cellular_component	Any plasma membrane part that is part of a growing cell tip.
GO:1902930	regulation of alcohol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.
GO:1902931	negative regulation of alcohol biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.
GO:1902932	positive regulation of alcohol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.
GO:1902933	isopentenol metabolic process	biological_process	The chemical reactions and pathways involving isopentenol.
GO:1902934	isopentenol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of isopentenol.
GO:1902935	protein localization to septin ring	biological_process	A process in which a protein is transported to, or maintained in, a location within a septin ring.
GO:1902936	phosphatidylinositol bisphosphate binding	molecular_function	Binding to phosphatidylinositol bisphosphate.
GO:1902937	inward rectifier potassium channel complex	cellular_component	A protein complex which is capable of inward rectifier potassium channel activity.
GO:1902938	regulation of intracellular calcium activated chloride channel activity	biological_process	Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity.
GO:1902939	negative regulation of intracellular calcium activated chloride channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity.
GO:1902940	positive regulation of intracellular calcium activated chloride channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity.
GO:1902941	regulation of voltage-gated chloride channel activity	biological_process	Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity.
GO:1902942	negative regulation of voltage-gated chloride channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity.
GO:1902943	positive regulation of voltage-gated chloride channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.
GO:1902944	aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	molecular_function	Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.
GO:1902945	metalloendopeptidase activity involved in amyloid precursor protein catabolic process	molecular_function	Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.
GO:1902946	protein localization to early endosome	biological_process	A process in which a protein is transported to, or maintained in, a location within an early endosome.
GO:1902947	regulation of tau-protein kinase activity	biological_process	Any process that modulates the frequency, rate or extent of tau-protein kinase activity.
GO:1902948	negative regulation of tau-protein kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity.
GO:1902949	positive regulation of tau-protein kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.
GO:1902950	regulation of dendritic spine maintenance	biological_process	Any process that modulates the frequency, rate or extent of dendritic spine maintenance.
GO:1902951	negative regulation of dendritic spine maintenance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
GO:1902952	positive regulation of dendritic spine maintenance	biological_process	Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.
GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport	biological_process	Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
GO:1902954	regulation of early endosome to recycling endosome transport	biological_process	Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.
GO:1902955	positive regulation of early endosome to recycling endosome transport	biological_process	Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.
GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902963	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902964	positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
GO:1902965	regulation of protein localization to early endosome	biological_process	Any process that modulates the frequency, rate or extent of protein localization to early endosome.
GO:1902966	positive regulation of protein localization to early endosome	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.
GO:1902967	protein localization to mitotic spindle midzone	biological_process	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.
GO:1902969	mitotic DNA replication	biological_process	Any nuclear DNA replication that is involved in a mitotic cell cycle.
GO:1902970	premeiotic DNA replication DNA duplex unwinding	biological_process	Any DNA duplex unwinding involved in meiotic cell cycle DNA replication.
GO:1902971	mitotic DNA replication DNA duplex unwinding	biological_process	Any DNA duplex unwinding involved in mitotic cell cycle DNA replication.
GO:1902972	premeiotic DNA replication DNA ligation	biological_process	Any DNA ligation involved in meiotic cell cycle DNA replication.
GO:1902973	mitotic DNA replication DNA ligation	biological_process	Any DNA ligation involved in mitotic cell cycle DNA replication.
GO:1902974	meiotic DNA replication initiation	biological_process	Any DNA replication initiation involved in meiotic cell cycle DNA replication.
GO:1902975	mitotic DNA replication initiation	biological_process	Any DNA replication initiation involved in mitotic cell cycle DNA replication.
GO:1902976	premeiotic DNA replication preinitiation complex assembly	biological_process	Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle.
GO:1902977	mitotic DNA replication preinitiation complex assembly	biological_process	Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle.
GO:1902978	premeiotic DNA replication termination	biological_process	Any DNA replication termination involved in meiotic cell cycle DNA replication.
GO:1902979	mitotic DNA replication termination	biological_process	Any DNA replication termination involved in mitotic cell cycle DNA replication.
GO:1902980	synthesis of RNA primer involved in premeiotic DNA replication	biological_process	Any synthesis of RNA primer involved in meiotic cell cycle DNA replication.
GO:1902981	synthesis of RNA primer involved in mitotic DNA replication	biological_process	Any synthesis of RNA primer involved in mitotic cell cycle DNA replication.
GO:1902982	DNA strand elongation involved in premeiotic DNA replication	biological_process	Any DNA strand elongation involved in meiotic cell cycle DNA replication.
GO:1902983	DNA strand elongation involved in mitotic DNA replication	biological_process	Any DNA strand elongation involved in mitotic cell cycle DNA replication.
GO:1902984	pre-replicative complex assembly involved in premeiotic DNA replication	biological_process	Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication.
GO:1902985	mitotic pre-replicative complex assembly	biological_process	Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication.
GO:1902986	regulation of lysine biosynthetic process via aminoadipic acid	biological_process	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.
GO:1902987	negative regulation of lysine biosynthetic process via aminoadipic acid	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.
GO:1902988	neurofibrillary tangle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.
GO:1902989	meiotic telomere maintenance via semi-conservative replication	biological_process	Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle.
GO:1902990	mitotic telomere maintenance via semi-conservative replication	biological_process	Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.
GO:1902991	regulation of amyloid precursor protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.
GO:1902992	negative regulation of amyloid precursor protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process.
GO:1902993	positive regulation of amyloid precursor protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process.
GO:1902994	regulation of phospholipid efflux	biological_process	Any process that modulates the frequency, rate or extent of phospholipid efflux.
GO:1902995	positive regulation of phospholipid efflux	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipid efflux.
GO:1902996	regulation of neurofibrillary tangle assembly	biological_process	Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly.
GO:1902997	negative regulation of neurofibrillary tangle assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.
GO:1902998	positive regulation of neurofibrillary tangle assembly	biological_process	Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.
GO:1902999	negative regulation of phospholipid efflux	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux.
GO:1903000	regulation of lipid transport across blood-brain barrier	biological_process	Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.
GO:1903001	negative regulation of lipid transport across blood-brain barrier	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.
GO:1903002	positive regulation of lipid transport across blood-brain barrier	biological_process	Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.
GO:1903003	positive regulation of protein deubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein deubiquitination.
GO:1903004	regulation of protein K63-linked deubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination.
GO:1903005	negative regulation of protein K63-linked deubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination.
GO:1903006	positive regulation of protein K63-linked deubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.
GO:1903007	positive regulation of Lys63-specific deubiquitinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity.
GO:1903008	organelle disassembly	biological_process	The disaggregation of an organelle into its constituent components.
GO:1903009	proteasome complex disassembly	biological_process	The disaggregation of a proteasome complex into its constituent components.
GO:1903010	regulation of bone development	biological_process	Any process that modulates the frequency, rate or extent of bone development.
GO:1903011	negative regulation of bone development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bone development.
GO:1903012	positive regulation of bone development	biological_process	Any process that activates or increases the frequency, rate or extent of bone development.
GO:1903013	response to differentiation-inducing factor 1	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
GO:1903014	cellular response to differentiation-inducing factor 1	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
GO:1903015	regulation of exo-alpha-sialidase activity	biological_process	Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity.
GO:1903016	negative regulation of exo-alpha-sialidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.
GO:1903017	positive regulation of exo-alpha-sialidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.
GO:1903018	regulation of glycoprotein metabolic process	biological_process	Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.
GO:1903019	negative regulation of glycoprotein metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
GO:1903020	positive regulation of glycoprotein metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.
GO:1903021	regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	biological_process	Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.
GO:1903022	positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	biological_process	Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.
GO:1903023	regulation of ascospore-type prospore membrane formation	biological_process	Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane.
GO:1903024	positive regulation of ascospore-type prospore membrane formation	biological_process	Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane.
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	biological_process	Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
GO:1903027	regulation of opsonization	biological_process	Any process that modulates the frequency, rate or extent of opsonization.
GO:1903028	positive regulation of opsonization	biological_process	Any process that activates or increases the frequency, rate or extent of opsonization.
GO:1903031	regulation of microtubule plus-end binding	biological_process	Any process that modulates the frequency, rate or extent of microtubule plus-end binding.
GO:1903032	negative regulation of microtubule plus-end binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding.
GO:1903033	positive regulation of microtubule plus-end binding	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.
GO:1903034	regulation of response to wounding	biological_process	Any process that modulates the frequency, rate or extent of response to wounding.
GO:1903035	negative regulation of response to wounding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.
GO:1903036	positive regulation of response to wounding	biological_process	Any process that activates or increases the frequency, rate or extent of response to wounding.
GO:1903037	regulation of leukocyte cell-cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.
GO:1903038	negative regulation of leukocyte cell-cell adhesion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.
GO:1903039	positive regulation of leukocyte cell-cell adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.
GO:1903040	exon-exon junction complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.
GO:1903041	regulation of chondrocyte hypertrophy	biological_process	Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.
GO:1903042	negative regulation of chondrocyte hypertrophy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.
GO:1903043	positive regulation of chondrocyte hypertrophy	biological_process	Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.
GO:1903044	protein localization to membrane raft	biological_process	A process in which a protein is transported to, or maintained in, a location within a membrane raft.
GO:1903045	neural crest cell migration involved in sympathetic nervous system development	biological_process	Any neural crest cell migration that is involved in sympathetic nervous system development.
GO:1903046	meiotic cell cycle process	biological_process	A process that is part of the meiotic cell cycle.
GO:1903047	mitotic cell cycle process	biological_process	A process that is part of the mitotic cell cycle.
GO:1903048	regulation of acetylcholine-gated cation channel activity	biological_process	Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.
GO:1903049	negative regulation of acetylcholine-gated cation channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity.
GO:1903050	regulation of proteolysis involved in protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.
GO:1903051	negative regulation of proteolysis involved in protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process.
GO:1903052	positive regulation of proteolysis involved in protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process.
GO:1903053	regulation of extracellular matrix organization	biological_process	Any process that modulates the frequency, rate or extent of extracellular matrix organization.
GO:1903054	negative regulation of extracellular matrix organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
GO:1903055	positive regulation of extracellular matrix organization	biological_process	Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
GO:1903056	regulation of melanosome organization	biological_process	Any process that modulates the frequency, rate or extent of melanosome organization.
GO:1903057	negative regulation of melanosome organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.
GO:1903058	positive regulation of melanosome organization	biological_process	Any process that activates or increases the frequency, rate or extent of melanosome organization.
GO:1903059	regulation of protein lipidation	biological_process	Any process that modulates the frequency, rate or extent of protein lipidation.
GO:1903060	negative regulation of protein lipidation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation.
GO:1903061	positive regulation of protein lipidation	biological_process	Any process that activates or increases the frequency, rate or extent of protein lipidation.
GO:1903062	regulation of reverse cholesterol transport	biological_process	Any process that modulates the frequency, rate or extent of reverse cholesterol transport.
GO:1903063	negative regulation of reverse cholesterol transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.
GO:1903064	positive regulation of reverse cholesterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport.
GO:1903066	regulation of protein localization to cell tip	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell tip.
GO:1903067	negative regulation of protein localization to cell tip	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.
GO:1903068	positive regulation of protein localization to cell tip	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.
GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
GO:1903072	regulation of death-inducing signaling complex assembly	biological_process	Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.
GO:1903073	negative regulation of death-inducing signaling complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.
GO:1903074	TRAIL death-inducing signaling complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.
GO:1903075	pyridoxine import across plasma membrane	biological_process	The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903076	regulation of protein localization to plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
GO:1903077	negative regulation of protein localization to plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.
GO:1903078	positive regulation of protein localization to plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
GO:1903080	regulation of C-C chemokine receptor CCR7 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
GO:1903081	negative regulation of C-C chemokine receptor CCR7 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
GO:1903082	positive regulation of C-C chemokine receptor CCR7 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
GO:1903083	protein localization to condensed chromosome	biological_process	A process in which a protein is transported to, or maintained in, a location within a condensed chromosome.
GO:1903084	protein localization to condensed nuclear chromosome	biological_process	A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome.
GO:1903085	regulation of sinapate ester biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.
GO:1903086	negative regulation of sinapate ester biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.
GO:1903087	mitotic spindle pole body duplication	biological_process	Any spindle pole body duplication that is involved in the mitotic cell cycle.
GO:1903088	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	biological_process	The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane.
GO:1903089	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity	molecular_function	Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.
GO:1903090	pyridoxal transmembrane transport	biological_process	The process in which pyridoxal is transported across a membrane.
GO:1903091	pyridoxamine transmembrane transport	biological_process	The process in which pyridoxamine is transported across a membrane.
GO:1903092	pyridoxine transmembrane transport	biological_process	The process in which pyridoxine is transported across a membrane.
GO:1903093	regulation of protein K48-linked deubiquitination	biological_process	Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination.
GO:1903094	negative regulation of protein K48-linked deubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.
GO:1903095	ribonuclease III complex	cellular_component	A protein complex which is capable of ribonuclease III activity.
GO:1903096	protein localization to meiotic spindle midzone	biological_process	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone.
GO:1903100	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process	biological_process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
GO:1903101	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
GO:1903102	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
GO:1903103	potassium:proton antiporter complex	cellular_component	A protein complex which is capable of potassium:proton antiporter activity.
GO:1903108	regulation of mitochondrial transcription	biological_process	Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.
GO:1903109	positive regulation of mitochondrial transcription	biological_process	Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.
GO:1903110	regulation of single-strand break repair via homologous recombination	biological_process	Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.
GO:1903111	negative regulation of single-strand break repair via homologous recombination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.
GO:1903112	positive regulation of single-strand break repair via homologous recombination	biological_process	Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.
GO:1903113	copper ion transmembrane transporter complex	cellular_component	A protein complex which is capable of copper ion transmembrane transporter activity.
GO:1903114	silver ion transmembrane transporter complex	cellular_component	A protein complex which is capable of silver ion transmembrane transporter activity.
GO:1903115	regulation of actin filament-based movement	biological_process	Any process that modulates the frequency, rate or extent of actin filament-based movement.
GO:1903116	positive regulation of actin filament-based movement	biological_process	Any process that activates or increases the frequency, rate or extent of actin filament-based movement.
GO:1903119	protein localization to actin cytoskeleton	biological_process	A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.
GO:1903120	protein localization to actin filament bundle	biological_process	A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.
GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
GO:1903122	negative regulation of TRAIL-activated apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
GO:1903123	regulation of thioredoxin peroxidase activity	biological_process	Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.
GO:1903124	negative regulation of thioredoxin peroxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.
GO:1903125	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	biological_process	A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.
GO:1903126	negative regulation of centriole-centriole cohesion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.
GO:1903127	positive regulation of centriole-centriole cohesion	biological_process	Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.
GO:1903131	mononuclear cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.
GO:1903132	regulation of tube lumen cavitation	biological_process	Any process that modulates the frequency, rate or extent of tube lumen cavitation.
GO:1903133	negative regulation of tube lumen cavitation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation.
GO:1903135	cupric ion binding	molecular_function	Binding to a cupric ion, copper(2+).
GO:1903136	cuprous ion binding	molecular_function	Binding to a cuprous ion, copper(1+).
GO:1903137	regulation of cell wall integrity MAPK cascade	biological_process	Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
GO:1903138	negative regulation of cell wall integrity MAPK cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
GO:1903139	positive regulation of cell wall integrity MAPK cascade	biological_process	Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
GO:1903140	regulation of establishment of endothelial barrier	biological_process	Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.
GO:1903141	negative regulation of establishment of endothelial barrier	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.
GO:1903142	positive regulation of establishment of endothelial barrier	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.
GO:1903143	adrenomedullin receptor complex	cellular_component	A transmembrane, G protein-coupled signaling receptor complex which is capable of adrenomedullin receptor activity.
GO:1903144	actomyosin contractile ring actin filament	cellular_component	Any actin filament that is part of a actomyosin contractile ring.
GO:1903145	actin filament of cell cortex of cell tip	cellular_component	Any actin filament that is part of a cell cortex of cell tip.
GO:1903146	regulation of autophagy of mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
GO:1903147	negative regulation of autophagy of mitochondrion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.
GO:1903165	response to polycyclic arene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.
GO:1903166	cellular response to polycyclic arene	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.
GO:1903167	regulation of pyrroline-5-carboxylate reductase activity	biological_process	Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.
GO:1903168	positive regulation of pyrroline-5-carboxylate reductase activity	biological_process	Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.
GO:1903169	regulation of calcium ion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.
GO:1903170	negative regulation of calcium ion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.
GO:1903173	fatty alcohol metabolic process	biological_process	The chemical reactions and pathways involving fatty alcohol.
GO:1903174	fatty alcohol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of fatty alcohol.
GO:1903175	fatty alcohol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of fatty alcohol.
GO:1903176	regulation of tyrosine 3-monooxygenase activity	biological_process	Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.
GO:1903177	negative regulation of tyrosine 3-monooxygenase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity.
GO:1903178	positive regulation of tyrosine 3-monooxygenase activity	biological_process	Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.
GO:1903179	regulation of dopamine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.
GO:1903180	negative regulation of dopamine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.
GO:1903181	positive regulation of dopamine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.
GO:1903182	regulation of SUMO transferase activity	biological_process	Any process that modulates the frequency, rate or extent of SUMO ligase activity.
GO:1903183	negative regulation of SUMO transferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity.
GO:1903184	L-dopa metabolic process	biological_process	The chemical reactions and pathways involving L-dopa.
GO:1903185	L-dopa biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of L-dopa.
GO:1903186	regulation of vitellogenesis	biological_process	Any process that modulates the frequency, rate or extent of vitellogenesis.
GO:1903187	negative regulation of vitellogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.
GO:1903188	positive regulation of vitellogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of vitellogenesis.
GO:1903189	glyoxal metabolic process	biological_process	The chemical reactions and pathways involving glyoxal.
GO:1903190	glyoxal catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of glyoxal.
GO:1903191	glyoxal biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of glyoxal.
GO:1903192	sesquarterpene metabolic process	biological_process	The chemical reactions and pathways involving sesquarterpene.
GO:1903193	sesquarterpene biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of sesquarterpene.
GO:1903195	regulation of L-dopa biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process.
GO:1903196	negative regulation of L-dopa biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process.
GO:1903197	positive regulation of L-dopa biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process.
GO:1903198	regulation of L-dopa decarboxylase activity	biological_process	Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity.
GO:1903199	negative regulation of L-dopa decarboxylase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.
GO:1903200	positive regulation of L-dopa decarboxylase activity	biological_process	Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.
GO:1903210	podocyte apoptotic process	biological_process	Any apoptotic process in a glomerular visceral epithelial cell.
GO:1903212	protein localization to mating-type region heterochromatin	biological_process	A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin.
GO:1903213	protein localization to subtelomeric heterochromatin	biological_process	A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin.
GO:1903214	regulation of protein targeting to mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
GO:1903215	negative regulation of protein targeting to mitochondrion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.
GO:1903216	regulation of protein processing involved in protein targeting to mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.
GO:1903217	negative regulation of protein processing involved in protein targeting to mitochondrion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.
GO:1903218	regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	biological_process	Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
GO:1903219	negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
GO:1903220	positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	biological_process	Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
GO:1903221	regulation of mitotic recombination-dependent replication fork processing	biological_process	Any process that modulates the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences.
GO:1903222	quinolinic acid transmembrane transport	biological_process	The process in which quinolinic acid is transported across a membrane.
GO:1903224	regulation of endodermal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of endodermal cell differentiation.
GO:1903225	negative regulation of endodermal cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.
GO:1903226	positive regulation of endodermal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.
GO:1903227	xanthosine metabolic process	biological_process	The chemical reactions and pathways involving xanthosine.
GO:1903228	xanthosine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of xanthosine.
GO:1903229	xanthosine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of xanthosine.
GO:1903231	mRNA base-pairing translational repressor activity	molecular_function	A translation repressor activity that acts by base-pairing with an mRNA. The binding can result in targeting the mRNA for degradation or interfering with mRNA translation, hence resulting in posttranscriptional gene silencing.
GO:1903232	melanosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter	biological_process	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
GO:1903234	negative regulation of calcium ion-dependent exocytosis of neurotransmitter	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
GO:1903235	positive regulation of calcium ion-dependent exocytosis of neurotransmitter	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
GO:1903236	regulation of leukocyte tethering or rolling	biological_process	Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling.
GO:1903237	negative regulation of leukocyte tethering or rolling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.
GO:1903238	positive regulation of leukocyte tethering or rolling	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.
GO:1903241	U2-type prespliceosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
GO:1903244	positive regulation of cardiac muscle hypertrophy in response to stress	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
GO:1903248	regulation of citrulline biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.
GO:1903249	negative regulation of citrulline biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.
GO:1903250	positive regulation of citrulline biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.
GO:1903251	multi-ciliated epithelial cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.
GO:1903252	hercynylcysteine sulfoxide metabolic process	biological_process	The chemical reactions and pathways involving hercynylcysteine sulfoxide.
GO:1903253	hercynylcysteine sulfoxide biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide.
GO:1903254	hercynylselenocysteine metabolic process	biological_process	The chemical reactions and pathways involving hercynylselenocysteine.
GO:1903255	hercynylselenocysteine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of hercynylselenocysteine.
GO:1903256	selenoneine metabolic process	biological_process	The chemical reactions and pathways involving selenoneine.
GO:1903257	selenoneine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of selenoneine.
GO:1903258	sorbose import across plasma membrane	biological_process	The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903259	exon-exon junction complex disassembly	biological_process	The disaggregation of an exon-exon junction complex into its constituent components.
GO:1903260	protein localization to mating projection tip	biological_process	A process in which a protein is transported to, or maintained in, a location within a mating projection tip.
GO:1903264	nitrate reductase activity involved in anaerobic electron transport chain	molecular_function	Any nitrate reductase activity that is involved in anaerobic electron transport chain.
GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
GO:1903266	regulation of ornithine catabolic process	biological_process	Any process that modulates the frequency, rate or extent of ornithine catabolic process.
GO:1903267	negative regulation of ornithine catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.
GO:1903268	positive regulation of ornithine catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ornithine catabolic process.
GO:1903269	ornithine carbamoyltransferase inhibitor complex	cellular_component	A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity.
GO:1903270	regulation of cytoplasmic translational elongation through polyproline stretches	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
GO:1903271	negative regulation of cytoplasmic translational elongation through polyproline stretches	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
GO:1903272	positive regulation of cytoplasmic translational elongation through polyproline stretches	biological_process	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
GO:1903276	regulation of sodium ion export across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.
GO:1903277	negative regulation of sodium ion export across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.
GO:1903278	positive regulation of sodium ion export across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.
GO:1903279	regulation of calcium:sodium antiporter activity	biological_process	Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity.
GO:1903280	negative regulation of calcium:sodium antiporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity.
GO:1903281	positive regulation of calcium:sodium antiporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity.
GO:1903282	regulation of glutathione peroxidase activity	biological_process	Any process that modulates the frequency, rate or extent of glutathione peroxidase activity.
GO:1903283	negative regulation of glutathione peroxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity.
GO:1903284	positive regulation of glutathione peroxidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity.
GO:1903285	positive regulation of hydrogen peroxide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.
GO:1903286	regulation of potassium ion import	biological_process	Any process that modulates the frequency, rate or extent of potassium ion import.
GO:1903287	negative regulation of potassium ion import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.
GO:1903288	positive regulation of potassium ion import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.
GO:1903292	protein localization to Golgi membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.
GO:1903293	phosphatase complex	cellular_component	A protein complex which is capable of phosphatase activity.
GO:1903294	regulation of glutamate secretion, neurotransmission	biological_process	Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.
GO:1903295	negative regulation of glutamate secretion, neurotransmission	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.
GO:1903296	positive regulation of glutamate secretion, neurotransmission	biological_process	Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.
GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
GO:1903299	regulation of hexokinase activity	biological_process	Any process that modulates the frequency, rate or extent of hexokinase activity.
GO:1903300	negative regulation of hexokinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity.
GO:1903301	positive regulation of hexokinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of hexokinase activity.
GO:1903302	regulation of pyruvate kinase activity	biological_process	Any process that modulates the frequency, rate or extent of pyruvate kinase activity.
GO:1903303	negative regulation of pyruvate kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.
GO:1903304	positive regulation of pyruvate kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity.
GO:1903305	regulation of regulated secretory pathway	biological_process	Any process that modulates the frequency, rate or extent of regulated secretory pathway.
GO:1903306	negative regulation of regulated secretory pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.
GO:1903307	positive regulation of regulated secretory pathway	biological_process	Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.
GO:1903311	regulation of mRNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of mRNA metabolic process.
GO:1903312	negative regulation of mRNA metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.
GO:1903313	positive regulation of mRNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.
GO:1903314	regulation of nitrogen cycle metabolic process	biological_process	Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.
GO:1903315	negative regulation of nitrogen cycle metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.
GO:1903316	positive regulation of nitrogen cycle metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.
GO:1903317	regulation of protein maturation	biological_process	Any process that modulates the frequency, rate or extent of protein maturation.
GO:1903318	negative regulation of protein maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
GO:1903319	positive regulation of protein maturation	biological_process	Any process that activates or increases the frequency, rate or extent of protein maturation.
GO:1903320	regulation of protein modification by small protein conjugation or removal	biological_process	Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal.
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal.
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	biological_process	Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal.
GO:1903323	regulation of snoRNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of snoRNA metabolic process.
GO:1903324	negative regulation of snoRNA metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.
GO:1903325	positive regulation of snoRNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.
GO:1903326	regulation of tRNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of tRNA metabolic process.
GO:1903327	negative regulation of tRNA metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.
GO:1903328	positive regulation of tRNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.
GO:1903329	regulation of iron-sulfur cluster assembly	biological_process	Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly.
GO:1903330	negative regulation of iron-sulfur cluster assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.
GO:1903331	positive regulation of iron-sulfur cluster assembly	biological_process	Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.
GO:1903332	regulation of protein folding	biological_process	Any process that modulates the frequency, rate or extent of protein folding.
GO:1903333	negative regulation of protein folding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.
GO:1903334	positive regulation of protein folding	biological_process	Any process that activates or increases the frequency, rate or extent of protein folding.
GO:1903335	regulation of vacuolar transport	biological_process	Any process that modulates the frequency, rate or extent of vacuolar transport.
GO:1903336	negative regulation of vacuolar transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.
GO:1903337	positive regulation of vacuolar transport	biological_process	Any process that activates or increases the frequency, rate or extent of vacuolar transport.
GO:1903338	regulation of cell wall organization or biogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.
GO:1903339	negative regulation of cell wall organization or biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.
GO:1903340	positive regulation of cell wall organization or biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.
GO:1903341	regulation of meiotic DNA double-strand break formation	biological_process	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.
GO:1903342	negative regulation of meiotic DNA double-strand break formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.
GO:1903343	positive regulation of meiotic DNA double-strand break formation	biological_process	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.
GO:1903344	regulation of protein polyglycylation	biological_process	Any process that modulates the frequency, rate or extent of protein polyglycylation.
GO:1903345	negative regulation of protein polyglycylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation.
GO:1903346	positive regulation of protein polyglycylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein polyglycylation.
GO:1903347	negative regulation of bicellular tight junction assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.
GO:1903348	positive regulation of bicellular tight junction assembly	biological_process	Any process that activates or increases the frequency, rate or extent of tight junction assembly.
GO:1903349	omegasome membrane	cellular_component	Any membrane that is part of an omegasome.
GO:1903350	response to dopamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.
GO:1903351	cellular response to dopamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.
GO:1903352	L-ornithine transmembrane transport	biological_process	The directed movement of L-ornithine across a membrane.
GO:1903353	regulation of nucleus organization	biological_process	Any process that modulates the frequency, rate or extent of nucleus organization.
GO:1903354	regulation of distal tip cell migration	biological_process	Any process that modulates the frequency, rate or extent of distal tip cell migration.
GO:1903355	negative regulation of distal tip cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.
GO:1903356	positive regulation of distal tip cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of distal tip cell migration.
GO:1903357	regulation of transcription initiation by RNA polymerase I	biological_process	Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter.
GO:1903358	regulation of Golgi organization	biological_process	Any process that modulates the frequency, rate or extent of Golgi organization.
GO:1903359	lateral cortical node assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node.
GO:1903360	protein localization to lateral cortical node	biological_process	A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.
GO:1903361	protein localization to basolateral plasma membrane	biological_process	Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane.
GO:1903365	regulation of fear response	biological_process	Any process that modulates the frequency, rate or extent of fear response.
GO:1903366	negative regulation of fear response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fear response.
GO:1903367	positive regulation of fear response	biological_process	Any process that activates or increases the frequency, rate or extent of fear response.
GO:1903368	regulation of foraging behavior	biological_process	Any process that modulates the frequency, rate or extent of foraging behavior.
GO:1903369	negative regulation of foraging behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior.
GO:1903370	positive regulation of foraging behavior	biological_process	Any process that activates or increases the frequency, rate or extent of foraging behavior.
GO:1903371	regulation of endoplasmic reticulum tubular network organization	biological_process	Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization.
GO:1903372	negative regulation of endoplasmic reticulum tubular network organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization.
GO:1903373	positive regulation of endoplasmic reticulum tubular network organization	biological_process	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.
GO:1903375	facioacoustic ganglion development	biological_process	The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.
GO:1903376	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
GO:1903379	regulation of mitotic chromosome condensation	biological_process	Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.
GO:1903380	positive regulation of mitotic chromosome condensation	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.
GO:1903381	regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.
GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.
GO:1903383	regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.
GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.
GO:1903385	regulation of homophilic cell adhesion	biological_process	Any process that modulates the frequency, rate or extent of homophilic cell adhesion.
GO:1903386	negative regulation of homophilic cell adhesion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion.
GO:1903387	positive regulation of homophilic cell adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.
GO:1903388	regulation of synaptic vesicle uncoating	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating.
GO:1903389	negative regulation of synaptic vesicle uncoating	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.
GO:1903390	positive regulation of synaptic vesicle uncoating	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.
GO:1903391	regulation of adherens junction organization	biological_process	Any process that modulates the frequency, rate or extent of adherens junction organization.
GO:1903392	negative regulation of adherens junction organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.
GO:1903393	positive regulation of adherens junction organization	biological_process	Any process that activates or increases the frequency, rate or extent of adherens junction organization.
GO:1903394	protein localization to kinetochore involved in kinetochore assembly	biological_process	Any protein localization to kinetochore that is involved in kinetochore assembly.
GO:1903395	regulation of secondary cell septum biogenesis	biological_process	Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis.
GO:1903396	negative regulation of secondary cell septum biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.
GO:1903397	positive regulation of secondary cell septum biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.
GO:1903401	L-lysine transmembrane transport	biological_process	The directed movement of L-lysine across a membrane.
GO:1903402	regulation of renal phosphate excretion	biological_process	Any process that modulates the frequency, rate or extent of renal phosphate excretion.
GO:1903403	negative regulation of renal phosphate excretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.
GO:1903404	positive regulation of renal phosphate excretion	biological_process	Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.
GO:1903405	protein localization to nuclear body	biological_process	A process in which a protein is transported to, or maintained in, a location within a nuclear body.
GO:1903406	regulation of P-type sodium:potassium-exchanging transporter activity	biological_process	Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
GO:1903407	negative regulation of P-type sodium:potassium-exchanging transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
GO:1903408	positive regulation of P-type sodium:potassium-exchanging transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
GO:1903409	reactive oxygen species biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.
GO:1903412	response to bile acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.
GO:1903413	cellular response to bile acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.
GO:1903415	flavonoid transport from endoplasmic reticulum to plant-type vacuole	biological_process	The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.
GO:1903416	response to glycoside	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.
GO:1903418	protein localization to plasma membrane of cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip.
GO:1903419	protein localization to cortical endoplasmic reticulum	biological_process	A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.
GO:1903420	protein localization to endoplasmic reticulum tubular network	biological_process	A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.
GO:1903421	regulation of synaptic vesicle recycling	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.
GO:1903422	negative regulation of synaptic vesicle recycling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.
GO:1903423	positive regulation of synaptic vesicle recycling	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.
GO:1903424	fluoride transmembrane transport	biological_process	The process in which fluoride is transported across a membrane.
GO:1903425	fluoride transmembrane transporter activity	molecular_function	Enables the transfer of fluoride from one side of a membrane to the other.
GO:1903426	regulation of reactive oxygen species biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.
GO:1903429	regulation of cell maturation	biological_process	Any process that modulates the frequency, rate or extent of cell maturation.
GO:1903430	negative regulation of cell maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.
GO:1903431	positive regulation of cell maturation	biological_process	Any process that activates or increases the frequency, rate or extent of cell maturation.
GO:1903432	regulation of TORC1 signaling	biological_process	Any process that modulates the frequency, rate or extent of TORC1 signaling.
GO:1903433	regulation of constitutive secretory pathway	biological_process	Any process that modulates the frequency, rate or extent of constitutive secretory pathway.
GO:1903434	negative regulation of constitutive secretory pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway.
GO:1903435	positive regulation of constitutive secretory pathway	biological_process	Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.
GO:1903436	regulation of mitotic cytokinetic process	biological_process	Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.
GO:1903437	negative regulation of mitotic cytokinetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.
GO:1903438	positive regulation of mitotic cytokinetic process	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.
GO:1903439	calcitonin family receptor complex	cellular_component	A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
GO:1903440	amylin receptor complex	cellular_component	A protein complex which is capable of amylin receptor activity.
GO:1903441	protein localization to ciliary membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
GO:1903442	response to lipoic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.
GO:1903443	cellular response to lipoic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.
GO:1903444	negative regulation of brown fat cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.
GO:1903445	protein transport from ciliary membrane to plasma membrane	biological_process	The directed movement of protein from ciliary membrane to plasma membrane.
GO:1903446	geraniol metabolic process	biological_process	The chemical reactions and pathways involving geraniol.
GO:1903447	geraniol catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of geraniol.
GO:1903448	geraniol biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of geraniol.
GO:1903449	androst-4-ene-3,17-dione biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione.
GO:1903450	regulation of G1 to G0 transition	biological_process	Any process that modulates the frequency, rate or extent of G1 to G0 transition.
GO:1903451	negative regulation of G1 to G0 transition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.
GO:1903452	positive regulation of G1 to G0 transition	biological_process	Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.
GO:1903454	regulation of androst-4-ene-3,17-dione biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
GO:1903455	negative regulation of androst-4-ene-3,17-dione biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
GO:1903456	positive regulation of androst-4-ene-3,17-dione biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
GO:1903457	lactate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactate.
GO:1903459	mitotic DNA replication lagging strand elongation	biological_process	Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.
GO:1903460	mitotic DNA replication leading strand elongation	biological_process	Any leading strand elongation that is involved in mitotic cell cycle DNA replication.
GO:1903461	Okazaki fragment processing involved in mitotic DNA replication	biological_process	Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.
GO:1903463	regulation of mitotic cell cycle DNA replication	biological_process	Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.
GO:1903464	negative regulation of mitotic cell cycle DNA replication	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.
GO:1903465	positive regulation of mitotic cell cycle DNA replication	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.
GO:1903466	regulation of mitotic DNA replication initiation	biological_process	Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
GO:1903467	negative regulation of mitotic DNA replication initiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
GO:1903468	positive regulation of DNA replication initiation	biological_process	Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
GO:1903469	removal of RNA primer involved in mitotic DNA replication	biological_process	Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication.
GO:1903471	regulation of mitotic actomyosin contractile ring contraction	biological_process	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
GO:1903472	negative regulation of mitotic actomyosin contractile ring contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
GO:1903473	positive regulation of mitotic actomyosin contractile ring contraction	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
GO:1903475	mitotic actomyosin contractile ring assembly	biological_process	Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
GO:1903476	protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	biological_process	Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.
GO:1903477	mitotic contractile ring actin filament bundle assembly	biological_process	Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly.
GO:1903479	mitotic actomyosin contractile ring assembly actin filament organization	biological_process	Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.
GO:1903487	regulation of lactation	biological_process	Any process that modulates the frequency, rate or extent of lactation.
GO:1903488	negative regulation of lactation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lactation.
GO:1903489	positive regulation of lactation	biological_process	Any process that activates or increases the frequency, rate or extent of lactation.
GO:1903490	positive regulation of mitotic cytokinesis	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.
GO:1903491	response to simvastatin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
GO:1903492	response to acetylsalicylate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.
GO:1903493	response to clopidogrel	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
GO:1903494	response to dehydroepiandrosterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.
GO:1903495	cellular response to dehydroepiandrosterone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.
GO:1903496	response to 11-deoxycorticosterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.
GO:1903497	cellular response to 11-deoxycorticosterone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.
GO:1903498	bundle sheath cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.
GO:1903499	regulation of mitotic actomyosin contractile ring assembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
GO:1903500	negative regulation of mitotic actomyosin contractile ring assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
GO:1903501	positive regulation of mitotic actomyosin contractile ring assembly	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
GO:1903502	translation repressor complex	cellular_component	A protein complex which is capable of translation repressor activity.
GO:1903503	ATPase inhibitor complex	cellular_component	A protein complex which is capable of ATPase inhibitor activity.
GO:1903504	regulation of mitotic spindle checkpoint	biological_process	Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.
GO:1903509	liposaccharide metabolic process	biological_process	The chemical reactions and pathways involving liposaccharide.
GO:1903510	mucopolysaccharide metabolic process	biological_process	The chemical reactions and pathways involving mucopolysaccharide.
GO:1903511	orotic acid metabolic process	biological_process	The chemical reactions and pathways involving orotic acid.
GO:1903512	phytanic acid metabolic process	biological_process	The chemical reactions and pathways involving phytanic acid.
GO:1903513	endoplasmic reticulum to cytosol transport	biological_process	The directed movement of substances from endoplasmic reticulum to cytosol.
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	biological_process	The directed movement of calcium ion from endoplasmic reticulum to cytosol.
GO:1903515	calcium ion transport from cytosol to endoplasmic reticulum	biological_process	The directed movement of calcium ion from cytosol to endoplasmic reticulum.
GO:1903516	regulation of single strand break repair	biological_process	Any process that modulates the frequency, rate or extent of single strand break repair.
GO:1903517	negative regulation of single strand break repair	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.
GO:1903518	positive regulation of single strand break repair	biological_process	Any process that activates or increases the frequency, rate or extent of single strand break repair.
GO:1903519	regulation of mammary gland involution	biological_process	Any process that modulates the frequency, rate or extent of mammary gland involution.
GO:1903520	negative regulation of mammary gland involution	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution.
GO:1903521	positive regulation of mammary gland involution	biological_process	Any process that activates or increases the frequency, rate or extent of mammary gland involution.
GO:1903522	regulation of blood circulation	biological_process	Any process that modulates the frequency, rate or extent of blood circulation.
GO:1903523	negative regulation of blood circulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.
GO:1903524	positive regulation of blood circulation	biological_process	Any process that activates or increases the frequency, rate or extent of blood circulation.
GO:1903525	regulation of membrane tubulation	biological_process	Any process that modulates the frequency, rate or extent of membrane tubulation.
GO:1903526	negative regulation of membrane tubulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.
GO:1903527	positive regulation of membrane tubulation	biological_process	Any process that activates or increases the frequency, rate or extent of membrane tubulation.
GO:1903528	regulation of dCDP biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of dCDP biosynthetic process.
GO:1903529	negative regulation of dCDP biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.
GO:1903530	regulation of secretion by cell	biological_process	Any process that modulates the frequency, rate or extent of secretion by cell.
GO:1903531	negative regulation of secretion by cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
GO:1903532	positive regulation of secretion by cell	biological_process	Any process that activates or increases the frequency, rate or extent of secretion by cell.
GO:1903533	regulation of protein targeting	biological_process	Any process that modulates the frequency, rate or extent of protein targeting.
GO:1903534	regulation of lactose biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of lactose biosynthetic process.
GO:1903535	negative regulation of lactose biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.
GO:1903536	positive regulation of lactose biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.
GO:1903537	meiotic cell cycle process involved in oocyte maturation	biological_process	Any meiotic cell cycle process that is involved in oocyte maturation.
GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation	biological_process	Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
GO:1903539	protein localization to postsynaptic membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.
GO:1903540	establishment of protein localization to postsynaptic membrane	biological_process	The directed movement of a protein to a specific location in a postsynaptic membrane.
GO:1903541	regulation of exosomal secretion	biological_process	Any process that modulates the frequency, rate or extent of exosomal secretion.
GO:1903542	negative regulation of exosomal secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.
GO:1903543	positive regulation of exosomal secretion	biological_process	Any process that activates or increases the frequency, rate or extent of exosomal secretion.
GO:1903544	response to butyrate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.
GO:1903545	cellular response to butyrate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.
GO:1903546	protein localization to photoreceptor outer segment	biological_process	A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.
GO:1903547	regulation of growth hormone activity	biological_process	Any process that modulates the frequency, rate or extent of growth hormone activity.
GO:1903548	negative regulation of growth hormone activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity.
GO:1903549	positive regulation of growth hormone activity	biological_process	Any process that activates or increases the frequency, rate or extent of growth hormone activity.
GO:1903551	regulation of extracellular exosome assembly	biological_process	Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.
GO:1903552	negative regulation of extracellular exosome assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.
GO:1903553	positive regulation of extracellular exosome assembly	biological_process	Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.
GO:1903554	G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium	biological_process	A G protein-coupled receptor signaling pathway that is involved in the defense response to Gram-negative bacterium.
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	biological_process	Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	biological_process	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
GO:1903558	3-cyano-L-alanine metabolic process	biological_process	The chemical reactions and pathways involving 3-cyano-L-alanine.
GO:1903559	3-cyano-L-alanine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine.
GO:1903560	3-cyano-L-alanine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.
GO:1903561	extracellular vesicle	cellular_component	Any vesicle that is part of the extracellular region.
GO:1903562	microtubule bundle formation involved in mitotic spindle midzone assembly	biological_process	Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis.
GO:1903563	microtubule bundle formation involved in horsetail-astral microtubule organization	biological_process	Any microtubule bundle formation that is involved in horsetail-astral microtubule organization.
GO:1903564	regulation of protein localization to cilium	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cilium.
GO:1903565	negative regulation of protein localization to cilium	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
GO:1903566	positive regulation of protein localization to cilium	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
GO:1903567	regulation of protein localization to ciliary membrane	biological_process	Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.
GO:1903568	negative regulation of protein localization to ciliary membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.
GO:1903569	positive regulation of protein localization to ciliary membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.
GO:1903570	regulation of protein kinase D signaling	biological_process	Any process that modulates the frequency, rate or extent of protein kinase D signaling.
GO:1903571	negative regulation of protein kinase D signaling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling.
GO:1903572	positive regulation of protein kinase D signaling	biological_process	Any process that activates or increases the frequency, rate or extent of protein kinase D signaling.
GO:1903573	negative regulation of response to endoplasmic reticulum stress	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
GO:1903574	negative regulation of cellular response to amino acid starvation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation.
GO:1903575	cornified envelope assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.
GO:1903576	response to L-arginine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
GO:1903577	cellular response to L-arginine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
GO:1903578	regulation of ATP metabolic process	biological_process	Any process that modulates the frequency, rate or extent of ATP metabolic process.
GO:1903579	negative regulation of ATP metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.
GO:1903580	positive regulation of ATP metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ATP metabolic process.
GO:1903581	regulation of basophil degranulation	biological_process	Any process that modulates the frequency, rate or extent of basophil degranulation.
GO:1903582	negative regulation of basophil degranulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.
GO:1903583	positive regulation of basophil degranulation	biological_process	Any process that activates or increases the frequency, rate or extent of basophil degranulation.
GO:1903584	regulation of histone deubiquitination	biological_process	Any process that modulates the frequency, rate or extent of histone deubiquitination.
GO:1903585	negative regulation of histone deubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination.
GO:1903586	positive regulation of histone deubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of histone deubiquitination.
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	biological_process	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
GO:1903590	regulation of lysozyme activity	biological_process	Any process that modulates the frequency, rate or extent of lysozyme activity.
GO:1903591	negative regulation of lysozyme activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity.
GO:1903592	positive regulation of lysozyme activity	biological_process	Any process that activates or increases the frequency, rate or extent of lysozyme activity.
GO:1903593	regulation of histamine secretion by mast cell	biological_process	Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.
GO:1903594	negative regulation of histamine secretion by mast cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.
GO:1903595	positive regulation of histamine secretion by mast cell	biological_process	Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.
GO:1903596	regulation of gap junction assembly	biological_process	Any process that modulates the frequency, rate or extent of gap junction assembly.
GO:1903597	negative regulation of gap junction assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.
GO:1903598	positive regulation of gap junction assembly	biological_process	Any process that activates or increases the frequency, rate or extent of gap junction assembly.
GO:1903599	positive regulation of autophagy of mitochondrion	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.
GO:1903600	glutaminase complex	cellular_component	A protein complex which is capable of glutaminase activity.
GO:1903601	thermospermine metabolic process	biological_process	The chemical reactions and pathways involving thermospermine.
GO:1903602	thermospermine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of thermospermine.
GO:1903603	thermospermine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of thermospermine.
GO:1903604	cytochrome metabolic process	biological_process	The chemical reactions and pathways involving a cytochrome.
GO:1903605	cytochrome biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a cytochrome.
GO:1903606	cytochrome c metabolic process	biological_process	The chemical reactions and pathways involving cytochrome c.
GO:1903607	cytochrome c biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of cytochrome c.
GO:1903608	protein localization to cytoplasmic stress granule	biological_process	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.
GO:1903609	negative regulation of inward rectifier potassium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.
GO:1903610	regulation of calcium-dependent ATPase activity	biological_process	Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.
GO:1903611	negative regulation of calcium-dependent ATPase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.
GO:1903612	positive regulation of calcium-dependent ATPase activity	biological_process	Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.
GO:1903613	regulation of protein tyrosine phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity.
GO:1903614	negative regulation of protein tyrosine phosphatase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity.
GO:1903615	positive regulation of protein tyrosine phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity.
GO:1903617	positive regulation of mitotic cytokinesis, division site positioning	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning.
GO:1903618	regulation of transdifferentiation	biological_process	Any process that modulates the frequency, rate or extent of transdifferentiation.
GO:1903619	negative regulation of transdifferentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation.
GO:1903620	positive regulation of transdifferentiation	biological_process	Any process that activates or increases the frequency, rate or extent of transdifferentiation.
GO:1903621	protein localization to photoreceptor connecting cilium	biological_process	A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.
GO:1903622	regulation of RNA polymerase III activity	biological_process	Any process that modulates the frequency, rate or extent of RNA polymerase III activity.
GO:1903623	negative regulation of RNA polymerase III activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.
GO:1903624	regulation of DNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of DNA catabolic process.
GO:1903625	negative regulation of DNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.
GO:1903626	positive regulation of DNA catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of DNA catabolic process.
GO:1903629	positive regulation of dUTP diphosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.
GO:1903630	regulation of aminoacyl-tRNA ligase activity	biological_process	Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.
GO:1903634	negative regulation of leucine-tRNA ligase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.
GO:1903636	regulation of protein insertion into mitochondrial outer membrane	biological_process	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane.
GO:1903637	negative regulation of protein insertion into mitochondrial outer membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane.
GO:1903638	positive regulation of protein insertion into mitochondrial outer membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane.
GO:1903639	regulation of gastrin-induced gastric acid secretion	biological_process	Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion.
GO:1903640	negative regulation of gastrin-induced gastric acid secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.
GO:1903641	positive regulation of gastrin-induced gastric acid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion.
GO:1903642	regulation of recombination hotspot binding	biological_process	Any process that modulates the frequency, rate or extent of recombination hotspot binding.
GO:1903643	positive regulation of recombination hotspot binding	biological_process	Any process that activates or increases the frequency, rate or extent of recombination hotspot binding.
GO:1903644	regulation of chaperone-mediated protein folding	biological_process	Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding.
GO:1903645	negative regulation of chaperone-mediated protein folding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding.
GO:1903646	positive regulation of chaperone-mediated protein folding	biological_process	Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.
GO:1903647	negative regulation of chlorophyll catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process.
GO:1903648	positive regulation of chlorophyll catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.
GO:1903649	regulation of cytoplasmic transport	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic transport.
GO:1903650	negative regulation of cytoplasmic transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
GO:1903651	positive regulation of cytoplasmic transport	biological_process	Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
GO:1903652	modulation by virus of host cytoplasmic transport	biological_process	Modulation by an infecting virus of host cytoplasmic transport.
GO:1903653	modulation by symbiont of host cell motility	biological_process	Modulation of host cell motility by a symbiont of that host.
GO:1903656	regulation of type IV pilus biogenesis	biological_process	Any process that modulates the frequency, rate or extent of type IV pilus biogenesis.
GO:1903657	negative regulation of type IV pilus biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.
GO:1903658	positive regulation of type IV pilus biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis.
GO:1903659	regulation of complement-dependent cytotoxicity	biological_process	Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.
GO:1903660	negative regulation of complement-dependent cytotoxicity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.
GO:1903661	positive regulation of complement-dependent cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.
GO:1903662	L-altrarate metabolic process	biological_process	The chemical reactions and pathways involving L-altrarate.
GO:1903663	L-altrarate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of L-altrarate.
GO:1903664	regulation of asexual reproduction	biological_process	Any process that modulates the frequency, rate or extent of asexual reproduction.
GO:1903665	negative regulation of asexual reproduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.
GO:1903666	positive regulation of asexual reproduction	biological_process	Any process that activates or increases the frequency, rate or extent of asexual reproduction.
GO:1903667	regulation of chemorepellent activity	biological_process	Any process that modulates the frequency, rate or extent of chemorepellent activity.
GO:1903668	negative regulation of chemorepellent activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity.
GO:1903669	positive regulation of chemorepellent activity	biological_process	Any process that activates or increases the frequency, rate or extent of chemorepellent activity.
GO:1903670	regulation of sprouting angiogenesis	biological_process	Any process that modulates the frequency, rate or extent of sprouting angiogenesis.
GO:1903671	negative regulation of sprouting angiogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.
GO:1903672	positive regulation of sprouting angiogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.
GO:1903673	mitotic cleavage furrow formation	biological_process	Any cleavage furrow formation that is involved in mitotic cell cycle.
GO:1903674	regulation of cap-dependent translational initiation	biological_process	Any process that modulates the frequency, rate or extent of cap-dependent translational initiation.
GO:1903675	negative regulation of cap-dependent translational initiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation.
GO:1903676	positive regulation of cap-dependent translational initiation	biological_process	Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation.
GO:1903677	regulation of cap-independent translational initiation	biological_process	Any process that modulates the frequency, rate or extent of cap-independent translational initiation.
GO:1903678	negative regulation of cap-independent translational initiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation.
GO:1903679	positive regulation of cap-independent translational initiation	biological_process	Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.
GO:1903680	acinar cell of sebaceous gland differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.
GO:1903681	regulation of epithelial cell-cell adhesion involved in epithelium migration	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
GO:1903682	negative regulation of epithelial cell-cell adhesion involved in epithelium migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
GO:1903683	positive regulation of epithelial cell-cell adhesion involved in epithelium migration	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
GO:1903684	regulation of border follicle cell migration	biological_process	Any process that modulates the frequency, rate or extent of border follicle cell migration.
GO:1903687	negative regulation of border follicle cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.
GO:1903688	positive regulation of border follicle cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of border follicle cell migration.
GO:1903689	regulation of wound healing, spreading of epidermal cells	biological_process	Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.
GO:1903690	negative regulation of wound healing, spreading of epidermal cells	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.
GO:1903691	positive regulation of wound healing, spreading of epidermal cells	biological_process	Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.
GO:1903692	methionine import across plasma membrane	biological_process	The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903696	protein localization to horsetail-astral microtubule array	biological_process	A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.
GO:1903697	negative regulation of microvillus assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.
GO:1903698	positive regulation of microvillus assembly	biological_process	Any process that activates or increases the frequency, rate or extent of microvillus assembly.
GO:1903699	tarsal gland development	biological_process	The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.
GO:1903700	caecum development	biological_process	The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.
GO:1903701	substantia propria of cornea development	biological_process	The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.
GO:1903702	esophagus development	biological_process	The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.
GO:1903703	enterocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte.
GO:1903704	negative regulation of siRNA processing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of siRNA processing.
GO:1903705	positive regulation of siRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of siRNA processing.
GO:1903706	regulation of hemopoiesis	biological_process	Any process that modulates the frequency, rate or extent of hemopoiesis.
GO:1903707	negative regulation of hemopoiesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.
GO:1903708	positive regulation of hemopoiesis	biological_process	Any process that activates or increases the frequency, rate or extent of hemopoiesis.
GO:1903709	uterine gland development	biological_process	The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.
GO:1903710	spermine transmembrane transport	biological_process	The process in which spermine is transported across a membrane.
GO:1903711	spermidine transmembrane transport	biological_process	The process in which spermidine is transported across a membrane.
GO:1903712	cysteine transmembrane transport	biological_process	The directed movement of cysteine across a membrane.
GO:1903713	asparagine transmembrane transport	biological_process	The directed movement of asparagine across a membrane.
GO:1903714	isoleucine transmembrane transport	biological_process	The directed movement of isoleucine across a membrane.
GO:1903715	regulation of aerobic respiration	biological_process	Any process that modulates the frequency, rate or extent of aerobic respiration.
GO:1903716	guanine transmembrane transport	biological_process	The process in which guanine is transported across a membrane.
GO:1903719	regulation of I-kappaB phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation.
GO:1903720	negative regulation of I-kappaB phosphorylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.
GO:1903721	positive regulation of I-kappaB phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.
GO:1903722	regulation of centriole elongation	biological_process	Any process that modulates the frequency, rate or extent of centriole elongation.
GO:1903723	negative regulation of centriole elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.
GO:1903724	positive regulation of centriole elongation	biological_process	Any process that activates or increases the frequency, rate or extent of centriole elongation.
GO:1903725	regulation of phospholipid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phospholipid metabolic process.
GO:1903726	negative regulation of phospholipid metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.
GO:1903727	positive regulation of phospholipid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.
GO:1903728	luteal cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.
GO:1903729	regulation of plasma membrane organization	biological_process	Any process that modulates the frequency, rate or extent of plasma membrane organization.
GO:1903730	regulation of phosphatidate phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.
GO:1903740	positive regulation of phosphatidate phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.
GO:1903741	negative regulation of phosphatidate phosphatase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity.
GO:1903742	regulation of anterograde synaptic vesicle transport	biological_process	Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.
GO:1903743	negative regulation of anterograde synaptic vesicle transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport.
GO:1903744	positive regulation of anterograde synaptic vesicle transport	biological_process	Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.
GO:1903745	negative regulation of pharyngeal pumping	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.
GO:1903746	positive regulation of pharyngeal pumping	biological_process	Any process that activates or increases the frequency, rate or extent of pharyngeal pumping.
GO:1903747	regulation of establishment of protein localization to mitochondrion	biological_process	Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.
GO:1903748	negative regulation of establishment of protein localization to mitochondrion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.
GO:1903749	positive regulation of establishment of protein localization to mitochondrion	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.
GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
GO:1903751	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
GO:1903752	positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
GO:1903753	negative regulation of p38MAPK cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.
GO:1903754	cortical microtubule plus-end	cellular_component	The plus-end of a cortical microtubule.
GO:1903755	positive regulation of SUMO transferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of SUMO transferase activity.
GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	biological_process	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
GO:1903761	negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
GO:1903762	positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
GO:1903763	gap junction channel activity involved in cell communication by electrical coupling	molecular_function	Any gap junction channel activity that is involved in cell communication by electrical coupling.
GO:1903764	regulation of potassium ion export across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.
GO:1903765	negative regulation of potassium ion export across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.
GO:1903766	positive regulation of potassium ion export across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.
GO:1903767	sweet taste receptor complex	cellular_component	A protein complex which is capable of sweet taste receptor activity.
GO:1903768	taste receptor complex	cellular_component	A protein complex which is capable of taste receptor activity.
GO:1903769	negative regulation of cell proliferation in bone marrow	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.
GO:1903770	negative regulation of beta-galactosidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity.
GO:1903771	positive regulation of beta-galactosidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.
GO:1903772	regulation of viral budding via host ESCRT complex	biological_process	Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.
GO:1903773	negative regulation of viral budding via host ESCRT complex	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex.
GO:1903774	positive regulation of viral budding via host ESCRT complex	biological_process	Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.
GO:1903775	regulation of DNA double-strand break processing	biological_process	Any process that modulates the frequency, rate or extent of DNA double-strand break processing.
GO:1903776	regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends	biological_process	Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.
GO:1903777	melibiose binding	molecular_function	Binding to melibiose.
GO:1903778	protein localization to vacuolar membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.
GO:1903779	regulation of cardiac conduction	biological_process	Any process that modulates the frequency, rate or extent of cardiac conduction.
GO:1903780	negative regulation of cardiac conduction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.
GO:1903781	positive regulation of cardiac conduction	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac conduction.
GO:1903782	regulation of sodium ion import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.
GO:1903783	negative regulation of sodium ion import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.
GO:1903784	positive regulation of sodium ion import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.
GO:1903785	L-valine transmembrane transport	biological_process	The directed movement of L-valine across a membrane.
GO:1903786	regulation of glutathione biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.
GO:1903787	negative regulation of glutathione biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.
GO:1903788	positive regulation of glutathione biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.
GO:1903789	regulation of amino acid transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.
GO:1903790	guanine nucleotide transmembrane transport	biological_process	The process in which a guanyl nucleotide is transported across a membrane.
GO:1903791	uracil transmembrane transport	biological_process	The process in which uracil is transported across a membrane.
GO:1903792	negative regulation of monoatomic anion transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.
GO:1903793	positive regulation of monoatomic anion transport	biological_process	Any process that activates or increases the frequency, rate or extent of anion transport.
GO:1903794	cortisol binding	molecular_function	Binding to cortisol.
GO:1903795	regulation of inorganic anion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport.
GO:1903796	negative regulation of inorganic anion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport.
GO:1903797	positive regulation of inorganic anion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport.
GO:1903798	regulation of miRNA processing	biological_process	Any process that modulates the frequency, rate or extent of microRNA processing.
GO:1903799	negative regulation of miRNA processing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microRNA processing.
GO:1903800	positive regulation of miRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of microRNA processing.
GO:1903801	L-leucine import across plasma membrane	biological_process	The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903803	L-glutamine import across plasma membrane	biological_process	The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903804	glycine import across plasma membrane	biological_process	The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903805	L-valine import across plasma membrane	biological_process	The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903806	L-isoleucine import across plasma membrane	biological_process	The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903807	L-threonine import across plasma membrane	biological_process	The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903808	L-tyrosine import across plasma membrane	biological_process	The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903810	L-histidine import across plasma membrane	biological_process	The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903811	L-asparagine import across plasma membrane	biological_process	The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1903812	L-serine import across plasma membrane	biological_process	The directed movement of L-serine into a cell.
GO:1903814	regulation of collecting lymphatic vessel constriction	biological_process	Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.
GO:1903815	negative regulation of collecting lymphatic vessel constriction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.
GO:1903816	positive regulation of collecting lymphatic vessel constriction	biological_process	Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction.
GO:1903817	negative regulation of voltage-gated potassium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.
GO:1903818	positive regulation of voltage-gated potassium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.
GO:1903823	telomere single strand break repair	biological_process	Single strand break repair that takes place in a telomere.
GO:1903824	negative regulation of telomere single strand break repair	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.
GO:1903825	organic acid transmembrane transport	biological_process	The process in which an organic acid is transported across a membrane.
GO:1903826	L-arginine transmembrane transport	biological_process	The directed movement of L-arginine across a membrane.
GO:1903828	negative regulation of protein localization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization.
GO:1903829	positive regulation of protein localization	biological_process	Any process that activates or increases the frequency, rate or extent of a protein localization.
GO:1903830	magnesium ion transmembrane transport	biological_process	The directed movement of magnesium ion across a membrane.
GO:1903831	signal transduction involved in cellular response to ammonium ion	biological_process	Any signal transduction that is involved in cellular response to ammonium ion.
GO:1903832	regulation of cellular response to amino acid starvation	biological_process	Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation.
GO:1903833	positive regulation of cellular response to amino acid starvation	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.
GO:1903837	regulation of mRNA 3'-UTR binding	biological_process	Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding.
GO:1903838	negative regulation of mRNA 3'-UTR binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding.
GO:1903839	positive regulation of mRNA 3'-UTR binding	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding.
GO:1903840	response to arsenite(3-)	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.
GO:1903841	cellular response to arsenite(3-)	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.
GO:1903842	response to arsenite ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
GO:1903843	cellular response to arsenite ion	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
GO:1903847	regulation of aorta morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of aorta morphogenesis.
GO:1903848	negative regulation of aorta morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.
GO:1903849	positive regulation of aorta morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.
GO:1903850	regulation of cristae formation	biological_process	Any process that modulates the frequency, rate or extent of cristae formation.
GO:1903851	negative regulation of cristae formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.
GO:1903852	positive regulation of cristae formation	biological_process	Any process that activates or increases the frequency, rate or extent of cristae formation.
GO:1903853	regulation of stress response to copper ion	biological_process	Any process that modulates the frequency, rate or extent of stress response to copper ion.
GO:1903854	negative regulation of stress response to copper ion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.
GO:1903855	positive regulation of stress response to copper ion	biological_process	Any process that activates or increases the frequency, rate or extent of stress response to copper ion.
GO:1903856	regulation of cytokinin dehydrogenase activity	biological_process	Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity.
GO:1903857	negative regulation of cytokinin dehydrogenase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity.
GO:1903858	protein localization to old growing cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location within an old growing cell tip.
GO:1903859	regulation of dendrite extension	biological_process	Any process that modulates the frequency, rate or extent of dendrite extension.
GO:1903860	negative regulation of dendrite extension	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.
GO:1903861	positive regulation of dendrite extension	biological_process	Any process that activates or increases the frequency, rate or extent of dendrite extension.
GO:1903862	positive regulation of oxidative phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.
GO:1903863	P granule assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a P granule.
GO:1903864	P granule disassembly	biological_process	The disaggregation of a P granule into its constituent components.
GO:1903865	sigma factor antagonist complex	cellular_component	A protein complex which is capable of sigma factor antagonist activity.
GO:1903866	palisade mesophyll development	biological_process	The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure.
GO:1903867	extraembryonic membrane development	biological_process	The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.
GO:1903868	regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	biological_process	Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
GO:1903869	negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
GO:1903870	positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	biological_process	Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
GO:1903871	DNA recombinase mediator complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex.
GO:1903872	regulation of DNA recombinase mediator complex assembly	biological_process	Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly.
GO:1903873	negative regulation of DNA recombinase mediator complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.
GO:1903875	corticosterone binding	molecular_function	Binding to corticosterone.
GO:1903876	11-deoxycortisol binding	molecular_function	Binding to 11-deoxycortisol.
GO:1903877	21-deoxycortisol binding	molecular_function	Binding to 21-deoxycortisol.
GO:1903878	11-deoxycorticosterone binding	molecular_function	Binding to 11-deoxycorticosterone.
GO:1903879	11beta-hydroxyprogesterone binding	molecular_function	Binding to 11beta-hydroxyprogesterone.
GO:1903880	17alpha-hydroxyprogesterone binding	molecular_function	Binding to 17alpha-hydroxyprogesterone.
GO:1903881	regulation of interleukin-17-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.
GO:1903882	negative regulation of interleukin-17-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.
GO:1903883	positive regulation of interleukin-17-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.
GO:1903884	regulation of chemokine (C-C motif) ligand 20 production	biological_process	Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
GO:1903885	negative regulation of chemokine (C-C motif) ligand 20 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
GO:1903886	positive regulation of chemokine (C-C motif) ligand 20 production	biological_process	Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
GO:1903888	regulation of plant epidermal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation.
GO:1903889	negative regulation of plant epidermal cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation.
GO:1903890	positive regulation of plant epidermal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation.
GO:1903891	regulation of ATF6-mediated unfolded protein response	biological_process	Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.
GO:1903892	negative regulation of ATF6-mediated unfolded protein response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.
GO:1903893	positive regulation of ATF6-mediated unfolded protein response	biological_process	Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.
GO:1903894	regulation of IRE1-mediated unfolded protein response	biological_process	Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
GO:1903895	negative regulation of IRE1-mediated unfolded protein response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
GO:1903896	positive regulation of IRE1-mediated unfolded protein response	biological_process	Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.
GO:1903897	regulation of PERK-mediated unfolded protein response	biological_process	Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.
GO:1903898	negative regulation of PERK-mediated unfolded protein response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.
GO:1903899	positive regulation of PERK-mediated unfolded protein response	biological_process	Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.
GO:1903900	regulation of viral life cycle	biological_process	Any process that modulates the frequency, rate or extent of viral life cycle.
GO:1903901	negative regulation of viral life cycle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.
GO:1903902	positive regulation of viral life cycle	biological_process	Any process that activates or increases the frequency, rate or extent of viral life cycle.
GO:1903903	regulation of establishment of T cell polarity	biological_process	Any process that modulates the frequency, rate or extent of establishment of T cell polarity.
GO:1903904	negative regulation of establishment of T cell polarity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.
GO:1903905	positive regulation of establishment of T cell polarity	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.
GO:1903906	regulation of plasma membrane raft polarization	biological_process	Any process that modulates the frequency, rate or extent of plasma membrane raft polarization.
GO:1903907	negative regulation of plasma membrane raft polarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.
GO:1903908	positive regulation of plasma membrane raft polarization	biological_process	Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.
GO:1903909	regulation of receptor clustering	biological_process	Any process that modulates the frequency, rate or extent of receptor clustering.
GO:1903910	negative regulation of receptor clustering	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.
GO:1903911	positive regulation of receptor clustering	biological_process	Any process that activates or increases the frequency, rate or extent of receptor clustering.
GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.
GO:1903913	regulation of fusion of virus membrane with host plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
GO:1903914	negative regulation of fusion of virus membrane with host plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
GO:1903915	positive regulation of fusion of virus membrane with host plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
GO:1903916	regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	biological_process	Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.
GO:1903917	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.
GO:1903918	regulation of actin filament severing	biological_process	Any process that modulates the frequency, rate or extent of actin filament severing.
GO:1903919	negative regulation of actin filament severing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.
GO:1903920	positive regulation of actin filament severing	biological_process	Any process that activates or increases the frequency, rate or extent of actin filament severing.
GO:1903921	regulation of protein processing in phagocytic vesicle	biological_process	Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle.
GO:1903922	negative regulation of protein processing in phagocytic vesicle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle.
GO:1903923	positive regulation of protein processing in phagocytic vesicle	biological_process	Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.
GO:1903924	estradiol binding	molecular_function	Binding to estradiol.
GO:1903925	response to bisphenol A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.
GO:1903926	cellular response to bisphenol A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.
GO:1903927	response to cyanide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.
GO:1903928	cellular response to cyanide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.
GO:1903929	primary palate development	biological_process	The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.
GO:1903930	regulation of pyrimidine-containing compound salvage	biological_process	Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage.
GO:1903931	positive regulation of pyrimidine-containing compound salvage	biological_process	Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.
GO:1903932	regulation of DNA primase activity	biological_process	Any process that modulates the frequency, rate or extent of DNA primase activity.
GO:1903933	negative regulation of DNA primase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.
GO:1903934	positive regulation of DNA primase activity	biological_process	Any process that activates or increases the frequency, rate or extent of DNA primase activity.
GO:1903935	response to sodium arsenite	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
GO:1903936	cellular response to sodium arsenite	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
GO:1903937	response to acrylamide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.
GO:1903938	cellular response to acrylamide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.
GO:1903939	regulation of TORC2 signaling	biological_process	Any process that modulates the frequency, rate or extent of TORC2 signaling.
GO:1903940	negative regulation of TORC2 signaling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling.
GO:1903941	negative regulation of respiratory gaseous exchange	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.
GO:1903942	positive regulation of respiratory gaseous exchange	biological_process	Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.
GO:1903943	regulation of hepatocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.
GO:1903944	negative regulation of hepatocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.
GO:1903945	positive regulation of hepatocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.
GO:1903946	negative regulation of ventricular cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.
GO:1903947	positive regulation of ventricular cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential.
GO:1903948	negative regulation of atrial cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.
GO:1903949	positive regulation of atrial cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.
GO:1903950	negative regulation of AV node cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.
GO:1903951	positive regulation of AV node cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of AV node cell action potential.
GO:1903952	regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	biological_process	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
GO:1903953	negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
GO:1903954	positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
GO:1903955	positive regulation of protein targeting to mitochondrion	biological_process	Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
GO:1903958	nitric-oxide synthase complex	cellular_component	A protein complex which is capable of nitric-oxide synthase activity.
GO:1903959	regulation of monoatomic anion transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of anion transmembrane transport.
GO:1903960	negative regulation of anion transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.
GO:1903961	positive regulation of anion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.
GO:1903962	arachidonate transmembrane transporter activity	molecular_function	Enables the transfer of arachidonate from one side of a membrane to the other.
GO:1903963	arachidonate transport	biological_process	The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1903964	monounsaturated fatty acid metabolic process	biological_process	The chemical reactions and pathways involving monounsaturated fatty acid.
GO:1903965	monounsaturated fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.
GO:1903966	monounsaturated fatty acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.
GO:1903967	response to micafungin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.
GO:1903968	cellular response to micafungin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.
GO:1903969	regulation of response to macrophage colony-stimulating factor	biological_process	Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor.
GO:1903970	negative regulation of response to macrophage colony-stimulating factor	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor.
GO:1903971	positive regulation of response to macrophage colony-stimulating factor	biological_process	Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.
GO:1903972	regulation of cellular response to macrophage colony-stimulating factor stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
GO:1903973	negative regulation of cellular response to macrophage colony-stimulating factor stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
GO:1903974	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
GO:1903975	regulation of glial cell migration	biological_process	Any process that modulates the frequency, rate or extent of glial cell migration.
GO:1903976	negative regulation of glial cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.
GO:1903977	positive regulation of glial cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of glial cell migration.
GO:1903978	regulation of microglial cell activation	biological_process	Any process that modulates the frequency, rate or extent of microglial cell activation.
GO:1903979	negative regulation of microglial cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.
GO:1903980	positive regulation of microglial cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of microglial cell activation.
GO:1903981	enterobactin binding	molecular_function	Binding to enterobactin.
GO:1903982	negative regulation of microvillus length	biological_process	A process that decreases the length of a microvillus.
GO:1903983	positive regulation of microvillus length	biological_process	A process that increases the length of a microvillus.
GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
GO:1903985	regulation of intestinal D-glucose absorption	biological_process	Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.
GO:1903988	iron ion export across plasma membrane	biological_process	The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:1903995	regulation of non-membrane spanning protein tyrosine kinase activity	biological_process	Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
GO:1903996	negative regulation of non-membrane spanning protein tyrosine kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
GO:1903997	positive regulation of non-membrane spanning protein tyrosine kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
GO:1903998	regulation of eating behavior	biological_process	Any process that modulates the frequency, rate or extent of eating behavior.
GO:1903999	negative regulation of eating behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.
GO:1904000	positive regulation of eating behavior	biological_process	Any process that activates or increases the frequency, rate or extent of eating behavior.
GO:1904002	regulation of sebum secreting cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.
GO:1904003	negative regulation of sebum secreting cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.
GO:1904004	positive regulation of sebum secreting cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.
GO:1904005	regulation of phospholipase D activity	biological_process	Any process that modulates the frequency, rate or extent of phospholipase D activity.
GO:1904006	negative regulation of phospholipase D activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.
GO:1904007	positive regulation of phospholipase D activity	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipase D activity.
GO:1904010	response to Aroclor 1254	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.
GO:1904011	cellular response to Aroclor 1254	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.
GO:1904014	response to serotonin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.
GO:1904015	cellular response to serotonin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.
GO:1904016	response to Thyroglobulin triiodothyronine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
GO:1904017	cellular response to Thyroglobulin triiodothyronine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
GO:1904018	positive regulation of vasculature development	biological_process	Any process that activates or increases the frequency, rate or extent of vasculature development.
GO:1904019	epithelial cell apoptotic process	biological_process	Any apoptotic process in an epithelial cell.
GO:1904020	regulation of G protein-coupled receptor internalization	biological_process	Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization.
GO:1904021	negative regulation of G protein-coupled receptor internalization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.
GO:1904022	positive regulation of G protein-coupled receptor internalization	biological_process	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization.
GO:1904023	regulation of glucose catabolic process to lactate via pyruvate	biological_process	Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
GO:1904024	negative regulation of glucose catabolic process to lactate via pyruvate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
GO:1904025	positive regulation of glucose catabolic process to lactate via pyruvate	biological_process	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
GO:1904026	regulation of collagen fibril organization	biological_process	Any process that modulates the frequency, rate or extent of collagen fibril organization.
GO:1904027	negative regulation of collagen fibril organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.
GO:1904028	positive regulation of collagen fibril organization	biological_process	Any process that activates or increases the frequency, rate or extent of collagen fibril organization.
GO:1904029	regulation of cyclin-dependent protein kinase activity	biological_process	Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.
GO:1904032	regulation of t-SNARE clustering	biological_process	Any process that modulates the frequency, rate or extent of t-SNARE clustering.
GO:1904033	negative regulation of t-SNARE clustering	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.
GO:1904034	positive regulation of t-SNARE clustering	biological_process	Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.
GO:1904035	regulation of epithelial cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.
GO:1904036	negative regulation of epithelial cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.
GO:1904037	positive regulation of epithelial cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.
GO:1904038	regulation of iron export across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:1904039	negative regulation of iron export across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:1904040	positive regulation of iron export across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:1904041	regulation of cystathionine beta-synthase activity	biological_process	Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity.
GO:1904042	negative regulation of cystathionine beta-synthase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.
GO:1904043	positive regulation of cystathionine beta-synthase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.
GO:1904044	response to aldosterone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.
GO:1904045	cellular response to aldosterone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.
GO:1904046	negative regulation of vascular endothelial growth factor production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.
GO:1904047	S-adenosyl-L-methionine binding	molecular_function	Binding to S-adenosyl-L-methionine.
GO:1904048	regulation of spontaneous neurotransmitter secretion	biological_process	Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.
GO:1904049	negative regulation of spontaneous neurotransmitter secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.
GO:1904050	positive regulation of spontaneous neurotransmitter secretion	biological_process	Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.
GO:1904051	regulation of protein targeting to vacuole involved in autophagy	biological_process	Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GO:1904052	negative regulation of protein targeting to vacuole involved in autophagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GO:1904053	positive regulation of protein targeting to vacuole involved in autophagy	biological_process	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GO:1904054	regulation of cholangiocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.
GO:1904055	negative regulation of cholangiocyte proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.
GO:1904056	positive regulation of cholangiocyte proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.
GO:1904057	negative regulation of sensory perception of pain	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.
GO:1904058	positive regulation of sensory perception of pain	biological_process	Any process that activates or increases the frequency, rate or extent of sensory perception of pain.
GO:1904059	regulation of locomotor rhythm	biological_process	Any process that modulates the frequency, rate or extent of locomotor rhythm.
GO:1904060	negative regulation of locomotor rhythm	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.
GO:1904061	positive regulation of locomotor rhythm	biological_process	Any process that activates or increases the frequency, rate or extent of locomotor rhythm.
GO:1904062	regulation of monoatomic cation transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of cation transmembrane transport.
GO:1904063	negative regulation of cation transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.
GO:1904064	positive regulation of cation transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.
GO:1904065	G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission	biological_process	Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission.
GO:1904066	G protein-coupled receptor signaling pathway involved in dauer larval development	biological_process	Any G protein-coupled receptor signaling pathway that is involved in dauer larval development.
GO:1904067	ascr#2 binding	molecular_function	Binding to ascr#2.
GO:1904068	G protein-coupled receptor signaling pathway involved in social behavior	biological_process	Any G protein-coupled receptor signaling pathway that is involved in social behavior.
GO:1904069	ascaroside metabolic process	biological_process	The chemical reactions and pathways involving ascaroside.
GO:1904070	ascaroside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ascaroside.
GO:1904071	presynaptic active zone assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
GO:1904072	presynaptic active zone disassembly	biological_process	The disaggregation of a presynaptic active zone into its constituent components.
GO:1904073	regulation of trophectodermal cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.
GO:1904074	negative regulation of trophectodermal cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.
GO:1904075	positive regulation of trophectodermal cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.
GO:1904076	regulation of estrogen biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.
GO:1904077	negative regulation of estrogen biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.
GO:1904078	positive regulation of estrogen biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.
GO:1904081	positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation	biological_process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation.
GO:1904082	pyrimidine nucleobase transmembrane transport	biological_process	The process in which pyrimidine is transported across a membrane.
GO:1904086	regulation of epiboly involved in gastrulation with mouth forming second	biological_process	Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
GO:1904088	positive regulation of epiboly involved in gastrulation with mouth forming second	biological_process	Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
GO:1904090	peptidase inhibitor complex	cellular_component	A protein complex which is capable of peptidase inhibitor activity.
GO:1904091	non-ribosomal peptide synthetase activity	molecular_function	Catalysis of a multistep reaction that produce non-ribosomal peptides. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.
GO:1904092	regulation of autophagic cell death	biological_process	Any process that modulates the frequency, rate or extent of autophagic cell death.
GO:1904093	negative regulation of autophagic cell death	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.
GO:1904094	positive regulation of autophagic cell death	biological_process	Any process that activates or increases the frequency, rate or extent of autophagic cell death.
GO:1904095	negative regulation of endosperm development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.
GO:1904096	protein tyrosine phosphatase complex	cellular_component	A protein complex which is capable of protein tyrosine phosphatase activity.
GO:1904097	acid phosphatase complex	cellular_component	A protein complex which is capable of acid phosphatase activity.
GO:1904098	regulation of protein O-linked glycosylation	biological_process	Any process that modulates the frequency, rate or extent of protein O-linked glycosylation.
GO:1904099	negative regulation of protein O-linked glycosylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation.
GO:1904100	positive regulation of protein O-linked glycosylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.
GO:1904101	response to acadesine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.
GO:1904102	cellular response to acadesine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.
GO:1904103	regulation of convergent extension involved in gastrulation	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.
GO:1904104	negative regulation of convergent extension involved in gastrulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation.
GO:1904105	positive regulation of convergent extension involved in gastrulation	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation.
GO:1904106	protein localization to microvillus	biological_process	A process in which a protein is transported to, or maintained in, a location within a microvillus.
GO:1904107	protein localization to microvillus membrane	biological_process	A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.
GO:1904108	protein localization to ciliary inversin compartment	biological_process	A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.
GO:1904109	positive regulation of cholesterol import	biological_process	Any process that activates or increases the frequency, rate or extent of cholesterol import.
GO:1904113	negative regulation of muscle filament sliding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding.
GO:1904114	positive regulation of muscle filament sliding	biological_process	Any process that activates or increases the frequency, rate or extent of muscle filament sliding.
GO:1904115	axon cytoplasm	cellular_component	Any cytoplasm that is part of a axon.
GO:1904116	response to vasopressin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.
GO:1904117	cellular response to vasopressin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.
GO:1904118	regulation of otic vesicle morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.
GO:1904119	negative regulation of otic vesicle morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.
GO:1904120	positive regulation of otic vesicle morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.
GO:1904121	phosphatidylethanolamine transfer activity	molecular_function	Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
GO:1904122	positive regulation of fatty acid beta-oxidation by octopamine signaling pathway	biological_process	An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation.
GO:1904123	positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway	biological_process	A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation.
GO:1904124	microglial cell migration	biological_process	The orderly movement of a microglial cell from one site to another.
GO:1904125	convergent extension involved in rhombomere morphogenesis	biological_process	Any convergent extension that is involved in rhombomere morphogenesis.
GO:1904126	convergent extension involved in notochord morphogenesis	biological_process	Any convergent extension that is involved in notochord morphogenesis.
GO:1904127	regulation of convergent extension involved in somitogenesis	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis.
GO:1904128	negative regulation of convergent extension involved in somitogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis.
GO:1904129	positive regulation of convergent extension involved in somitogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis.
GO:1904130	regulation of convergent extension involved in neural plate elongation	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation.
GO:1904131	negative regulation of convergent extension involved in neural plate elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation.
GO:1904132	positive regulation of convergent extension involved in neural plate elongation	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation.
GO:1904133	regulation of convergent extension involved in rhombomere morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
GO:1904134	negative regulation of convergent extension involved in rhombomere morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
GO:1904135	positive regulation of convergent extension involved in rhombomere morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
GO:1904136	regulation of convergent extension involved in notochord morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
GO:1904137	negative regulation of convergent extension involved in notochord morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
GO:1904138	positive regulation of convergent extension involved in notochord morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
GO:1904139	regulation of microglial cell migration	biological_process	Any process that modulates the frequency, rate or extent of microglial cell migration.
GO:1904140	negative regulation of microglial cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.
GO:1904141	positive regulation of microglial cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of microglial cell migration.
GO:1904142	negative regulation of carotenoid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.
GO:1904143	positive regulation of carotenoid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.
GO:1904144	phosphatidylinositol phosphate phosphatase complex	cellular_component	A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.
GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
GO:1904146	positive regulation of meiotic cell cycle process involved in oocyte maturation	biological_process	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
GO:1904147	response to nonylphenol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.
GO:1904148	cellular response to nonylphenol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.
GO:1904149	regulation of microglial cell mediated cytotoxicity	biological_process	Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity.
GO:1904150	negative regulation of microglial cell mediated cytotoxicity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.
GO:1904151	positive regulation of microglial cell mediated cytotoxicity	biological_process	Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.
GO:1904152	regulation of retrograde protein transport, ER to cytosol	biological_process	Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GO:1904153	negative regulation of retrograde protein transport, ER to cytosol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GO:1904154	positive regulation of retrograde protein transport, ER to cytosol	biological_process	Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GO:1904155	DN2 thymocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.
GO:1904156	DN3 thymocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.
GO:1904157	DN4 thymocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-.
GO:1904158	axonemal central apparatus assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus.
GO:1904159	megasporocyte differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte.
GO:1904160	protein localization to chloroplast starch grain	biological_process	A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.
GO:1904161	DNA synthesis involved in UV-damage excision repair	biological_process	Any DNA synthesis that is involved in UV-damage excision repair.
GO:1904170	regulation of bleb assembly	biological_process	Any process that modulates the frequency, rate or extent of bleb assembly.
GO:1904171	negative regulation of bleb assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.
GO:1904172	positive regulation of bleb assembly	biological_process	Any process that activates or increases the frequency, rate or extent of bleb assembly.
GO:1904176	carbon phosphorus lyase complex	cellular_component	A protein complex which is capable of carbon phosphorus lyase activity.
GO:1904177	regulation of adipose tissue development	biological_process	Any process that modulates the frequency, rate or extent of adipose tissue development.
GO:1904178	negative regulation of adipose tissue development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.
GO:1904179	positive regulation of adipose tissue development	biological_process	Any process that activates or increases the frequency, rate or extent of adipose tissue development.
GO:1904180	negative regulation of membrane depolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization.
GO:1904181	positive regulation of membrane depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of membrane depolarization.
GO:1904182	regulation of pyruvate dehydrogenase activity	biological_process	Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.
GO:1904183	negative regulation of pyruvate dehydrogenase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.
GO:1904184	positive regulation of pyruvate dehydrogenase activity	biological_process	Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.
GO:1904185	equatorial microtubule organizing center assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.
GO:1904186	post-anaphase microtubule array organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.
GO:1904187	regulation of transformation of host cell by virus	biological_process	Any process that modulates the frequency, rate or extent of transformation of host cell by virus.
GO:1904188	negative regulation of transformation of host cell by virus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.
GO:1904189	positive regulation of transformation of host cell by virus	biological_process	Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.
GO:1904191	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division	biological_process	Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division.
GO:1904192	regulation of cholangiocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.
GO:1904193	negative regulation of cholangiocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.
GO:1904194	positive regulation of cholangiocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.
GO:1904195	regulation of granulosa cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of granulosa cell proliferation.
GO:1904196	negative regulation of granulosa cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.
GO:1904197	positive regulation of granulosa cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.
GO:1904198	negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.
GO:1904199	positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.
GO:1904200	iodide transmembrane transport	biological_process	The process in which iodide is transported across a membrane.
GO:1904201	regulation of iodide transport	biological_process	Any process that modulates the frequency, rate or extent of iodide transport.
GO:1904202	negative regulation of iodide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.
GO:1904203	positive regulation of iodide transport	biological_process	Any process that activates or increases the frequency, rate or extent of iodide transport.
GO:1904204	regulation of skeletal muscle hypertrophy	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.
GO:1904205	negative regulation of skeletal muscle hypertrophy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.
GO:1904206	positive regulation of skeletal muscle hypertrophy	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.
GO:1904210	VCP-NPL4-UFD1 AAA ATPase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.
GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol	biological_process	Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol.
GO:1904212	regulation of iodide transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of iodide transmembrane transport.
GO:1904213	negative regulation of iodide transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport.
GO:1904214	positive regulation of iodide transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.
GO:1904215	regulation of protein import into chloroplast stroma	biological_process	Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.
GO:1904216	positive regulation of protein import into chloroplast stroma	biological_process	Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.
GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
GO:1904218	negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
GO:1904220	regulation of serine C-palmitoyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.
GO:1904221	negative regulation of serine C-palmitoyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.
GO:1904222	positive regulation of serine C-palmitoyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.
GO:1904223	regulation of glucuronosyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity.
GO:1904224	negative regulation of glucuronosyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity.
GO:1904225	positive regulation of glucuronosyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity.
GO:1904226	regulation of glycogen synthase activity, transferring glucose-1-phosphate	biological_process	Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
GO:1904227	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
GO:1904228	positive regulation of glycogen synthase activity, transferring glucose-1-phosphate	biological_process	Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
GO:1904229	regulation of succinate dehydrogenase activity	biological_process	Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity.
GO:1904230	negative regulation of succinate dehydrogenase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.
GO:1904231	positive regulation of succinate dehydrogenase activity	biological_process	Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity.
GO:1904232	regulation of aconitate hydratase activity	biological_process	Any process that modulates the frequency, rate or extent of aconitate hydratase activity.
GO:1904233	negative regulation of aconitate hydratase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity.
GO:1904234	positive regulation of aconitate hydratase activity	biological_process	Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity.
GO:1904235	regulation of substrate-dependent cell migration, cell attachment to substrate	biological_process	Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
GO:1904236	negative regulation of substrate-dependent cell migration, cell attachment to substrate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate	biological_process	Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
GO:1904238	pericyte cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.
GO:1904239	regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	biological_process	Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
GO:1904240	negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
GO:1904241	positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
GO:1904242	regulation of pancreatic trypsinogen secretion	biological_process	Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.
GO:1904243	negative regulation of pancreatic trypsinogen secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.
GO:1904244	positive regulation of pancreatic trypsinogen secretion	biological_process	Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.
GO:1904245	regulation of polynucleotide adenylyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity.
GO:1904246	negative regulation of polynucleotide adenylyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.
GO:1904247	positive regulation of polynucleotide adenylyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.
GO:1904248	regulation of age-related resistance	biological_process	Any process that modulates the extent of age-related resistance.
GO:1904249	negative regulation of age-related resistance	biological_process	Any process that stops, prevents or reduces the extent of age-related resistance.
GO:1904250	positive regulation of age-related resistance	biological_process	Any process that activates or increases the extent of age-related resistance.
GO:1904251	regulation of bile acid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of bile acid metabolic process.
GO:1904252	negative regulation of bile acid metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.
GO:1904253	positive regulation of bile acid metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.
GO:1904254	regulation of iron ion transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.
GO:1904255	negative regulation of iron ion transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity.
GO:1904256	positive regulation of iron ion transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity.
GO:1904257	zinc ion import into Golgi lumen	biological_process	The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi lumen.
GO:1904258	nuclear dicing body assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.
GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
GO:1904260	negative regulation of basement membrane assembly involved in embryonic body morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
GO:1904262	negative regulation of TORC1 signaling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
GO:1904263	positive regulation of TORC1 signaling	biological_process	Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
GO:1904266	regulation of Schwann cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.
GO:1904267	negative regulation of Schwann cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.
GO:1904268	positive regulation of Schwann cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.
GO:1904269	cell leading edge cell cortex	cellular_component	The cell cortex of the leading edge of a cell.
GO:1904270	pyroptosome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex.
GO:1904271	L-proline import across plasma membrane	biological_process	The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol.
GO:1904272	L-tryptophan import across plasma membrane	biological_process	The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol.
GO:1904273	L-alanine import across plasma membrane	biological_process	The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol.
GO:1904274	tricellular tight junction assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.
GO:1904275	tricellular tight junction disassembly	biological_process	The disaggregation of a tricellular tight junction into its constituent components.
GO:1904276	regulation of wax biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of wax biosynthetic process.
GO:1904277	negative regulation of wax biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.
GO:1904278	positive regulation of wax biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.
GO:1904279	regulation of transcription by RNA polymerase V	biological_process	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V.
GO:1904280	negative regulation of transcription by RNA polymerase V	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.
GO:1904281	positive regulation of transcription by RNA polymerase V	biological_process	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V.
GO:1904282	regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	biological_process	Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
GO:1904283	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
GO:1904284	positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	biological_process	Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
GO:1904285	regulation of protein-pyridoxal-5-phosphate linkage	biological_process	Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
GO:1904286	negative regulation of protein-pyridoxal-5-phosphate linkage	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
GO:1904287	positive regulation of protein-pyridoxal-5-phosphate linkage	biological_process	Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
GO:1904288	BAT3 complex binding	molecular_function	Binding to a BAT3 complex.
GO:1904289	regulation of mitotic DNA damage checkpoint	biological_process	Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.
GO:1904290	negative regulation of mitotic DNA damage checkpoint	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.
GO:1904291	positive regulation of mitotic DNA damage checkpoint	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.
GO:1904292	regulation of ERAD pathway	biological_process	Any process that modulates the frequency, rate or extent of ERAD pathway.
GO:1904293	negative regulation of ERAD pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.
GO:1904294	positive regulation of ERAD pathway	biological_process	Any process that activates or increases the frequency, rate or extent of ERAD pathway.
GO:1904295	regulation of osmolarity-sensing cation channel activity	biological_process	Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity.
GO:1904296	negative regulation of osmolarity-sensing cation channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity.
GO:1904297	positive regulation of osmolarity-sensing cation channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity.
GO:1904298	regulation of transcytosis	biological_process	Any process that modulates the frequency, rate or extent of transcytosis.
GO:1904299	negative regulation of transcytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis.
GO:1904300	positive regulation of transcytosis	biological_process	Any process that activates or increases the frequency, rate or extent of transcytosis.
GO:1904301	regulation of maternal process involved in parturition	biological_process	Any process that modulates the frequency, rate or extent of maternal process involved in parturition.
GO:1904302	negative regulation of maternal process involved in parturition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition.
GO:1904303	positive regulation of maternal process involved in parturition	biological_process	Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition.
GO:1904304	regulation of gastro-intestinal system smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
GO:1904305	negative regulation of gastro-intestinal system smooth muscle contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
GO:1904306	positive regulation of gastro-intestinal system smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
GO:1904307	response to desipramine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.
GO:1904308	cellular response to desipramine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.
GO:1904309	response to cordycepin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.
GO:1904310	cellular response to cordycepin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.
GO:1904311	response to gold(3+)	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.
GO:1904312	cellular response to gold(3+)	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.
GO:1904313	response to methamphetamine hydrochloride	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.
GO:1904314	cellular response to methamphetamine hydrochloride	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	molecular_function	Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
GO:1904316	response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.
GO:1904317	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.
GO:1904318	regulation of smooth muscle contraction involved in micturition	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.
GO:1904319	negative regulation of smooth muscle contraction involved in micturition	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition.
GO:1904320	positive regulation of smooth muscle contraction involved in micturition	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition.
GO:1904321	response to forskolin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
GO:1904322	cellular response to forskolin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
GO:1904323	regulation of inhibitory G protein-coupled receptor phosphorylation	biological_process	Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.
GO:1904324	negative regulation of inhibitory G protein-coupled receptor phosphorylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.
GO:1904325	positive regulation of inhibitory G protein-coupled receptor phosphorylation	biological_process	Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.
GO:1904326	negative regulation of circadian sleep/wake cycle, wakefulness	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness.
GO:1904327	protein localization to cytosolic proteasome complex	biological_process	A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.
GO:1904328	regulation of myofibroblast contraction	biological_process	Any process that modulates the frequency, rate or extent of myofibroblast contraction.
GO:1904329	negative regulation of myofibroblast contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction.
GO:1904330	positive regulation of myofibroblast contraction	biological_process	Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.
GO:1904331	regulation of error-prone translesion synthesis	biological_process	Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.
GO:1904332	negative regulation of error-prone translesion synthesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.
GO:1904333	positive regulation of error-prone translesion synthesis	biological_process	Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.
GO:1904334	heme import across plasma membrane	biological_process	The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol.
GO:1904335	regulation of ductus arteriosus closure	biological_process	Any process that modulates the frequency, rate or extent of ductus arteriosus closure.
GO:1904336	negative regulation of ductus arteriosus closure	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.
GO:1904337	positive regulation of ductus arteriosus closure	biological_process	Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure.
GO:1904338	regulation of dopaminergic neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.
GO:1904339	negative regulation of dopaminergic neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.
GO:1904340	positive regulation of dopaminergic neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.
GO:1904341	regulation of colon smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.
GO:1904342	negative regulation of colon smooth muscle contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.
GO:1904343	positive regulation of colon smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.
GO:1904344	regulation of gastric mucosal blood circulation	biological_process	Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.
GO:1904345	negative regulation of gastric mucosal blood circulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.
GO:1904346	positive regulation of gastric mucosal blood circulation	biological_process	Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.
GO:1904347	regulation of small intestine smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.
GO:1904348	negative regulation of small intestine smooth muscle contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.
GO:1904349	positive regulation of small intestine smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.
GO:1904350	regulation of protein catabolic process in the vacuole	biological_process	Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.
GO:1904351	negative regulation of protein catabolic process in the vacuole	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.
GO:1904352	positive regulation of protein catabolic process in the vacuole	biological_process	Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
GO:1904353	regulation of telomere capping	biological_process	Any process that modulates the frequency, rate or extent of telomere capping.
GO:1904354	negative regulation of telomere capping	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.
GO:1904355	positive regulation of telomere capping	biological_process	Any process that activates or increases the frequency, rate or extent of telomere capping.
GO:1904356	regulation of telomere maintenance via telomere lengthening	biological_process	Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	biological_process	Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
GO:1904359	regulation of spore germination	biological_process	Any process that modulates the frequency, rate or extent of spore germination.
GO:1904360	negative regulation of spore germination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of spore germination.
GO:1904361	positive regulation of spore germination	biological_process	Any process that activates or increases the frequency, rate or extent of spore germination.
GO:1904362	regulation of calcitonin secretion	biological_process	Any process that modulates the frequency, rate or extent of calcitonin secretion.
GO:1904363	negative regulation of calcitonin secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.
GO:1904364	positive regulation of calcitonin secretion	biological_process	Any process that activates or increases the frequency, rate or extent of calcitonin secretion.
GO:1904365	regulation of chemokinesis	biological_process	Any process that modulates the frequency, rate or extent of chemokinesis.
GO:1904366	negative regulation of chemokinesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.
GO:1904367	positive regulation of chemokinesis	biological_process	Any process that activates or increases the frequency, rate or extent of chemokinesis.
GO:1904368	regulation of sclerenchyma cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation.
GO:1904369	positive regulation of sclerenchyma cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation.
GO:1904370	regulation of protein localization to actin cortical patch	biological_process	Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.
GO:1904371	negative regulation of protein localization to actin cortical patch	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.
GO:1904372	positive regulation of protein localization to actin cortical patch	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.
GO:1904373	response to kainic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.
GO:1904374	cellular response to kainic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.
GO:1904375	regulation of protein localization to cell periphery	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell periphery.
GO:1904376	negative regulation of protein localization to cell periphery	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.
GO:1904377	positive regulation of protein localization to cell periphery	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.
GO:1904378	maintenance of unfolded protein involved in ERAD pathway	biological_process	Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
GO:1904379	protein localization to cytosolic proteasome complex involved in ERAD pathway	biological_process	Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation.
GO:1904380	endoplasmic reticulum mannose trimming	biological_process	Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).
GO:1904381	Golgi apparatus mannose trimming	biological_process	Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus.
GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	biological_process	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
GO:1904383	response to sodium phosphate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.
GO:1904384	cellular response to sodium phosphate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.
GO:1904385	cellular response to angiotensin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.
GO:1904386	response to L-phenylalanine derivative	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.
GO:1904387	cellular response to L-phenylalanine derivative	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.
GO:1904388	negative regulation of ncRNA transcription associated with protein coding gene TSS/TES	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES.
GO:1904389	rod bipolar cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.
GO:1904390	cone retinal bipolar cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.
GO:1904391	response to ciliary neurotrophic factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.
GO:1904392	cellular response to ciliary neurotrophic factor	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.
GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
GO:1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
GO:1904396	regulation of neuromuscular junction development	biological_process	Any process that modulates the frequency, rate or extent of neuromuscular junction development.
GO:1904397	negative regulation of neuromuscular junction development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.
GO:1904398	positive regulation of neuromuscular junction development	biological_process	Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.
GO:1904399	heparan sulfate binding	molecular_function	Binding to heparan sulfate.
GO:1904400	response to Thyroid stimulating hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.
GO:1904401	cellular response to Thyroid stimulating hormone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.
GO:1904402	response to nocodazole	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.
GO:1904403	cellular response to nocodazole	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.
GO:1904404	response to formaldehyde	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.
GO:1904405	cellular response to formaldehyde	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.
GO:1904406	negative regulation of nitric oxide metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process.
GO:1904407	positive regulation of nitric oxide metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process.
GO:1904408	melatonin binding	molecular_function	Binding to melatonin.
GO:1904409	regulation of secretory granule organization	biological_process	Any process that modulates the frequency, rate or extent of secretory granule organization.
GO:1904410	negative regulation of secretory granule organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.
GO:1904411	positive regulation of secretory granule organization	biological_process	Any process that activates or increases the frequency, rate or extent of secretory granule organization.
GO:1904412	regulation of cardiac ventricle development	biological_process	Any process that modulates the frequency, rate or extent of cardiac ventricle development.
GO:1904413	negative regulation of cardiac ventricle development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.
GO:1904414	positive regulation of cardiac ventricle development	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.
GO:1904415	regulation of xenophagy	biological_process	Any process that modulates the frequency, rate or extent of xenophagy.
GO:1904416	negative regulation of xenophagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.
GO:1904417	positive regulation of xenophagy	biological_process	Any process that activates or increases the frequency, rate or extent of xenophagy.
GO:1904418	regulation of telomeric loop formation	biological_process	Any process that modulates the frequency, rate or extent of telomeric loop formation.
GO:1904419	negative regulation of telomeric loop formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation.
GO:1904420	positive regulation of telomeric loop formation	biological_process	Any process that activates or increases the frequency, rate or extent of telomeric loop formation.
GO:1904421	response to D-galactosamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.
GO:1904422	cellular response to D-galactosamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.
GO:1904423	dehydrodolichyl diphosphate synthase complex	cellular_component	A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
GO:1904424	regulation of GTP binding	biological_process	Any process that modulates the frequency, rate or extent of GTP binding.
GO:1904425	negative regulation of GTP binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding.
GO:1904426	positive regulation of GTP binding	biological_process	Any process that activates or increases the frequency, rate or extent of GTP binding.
GO:1904427	positive regulation of calcium ion transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.
GO:1904428	negative regulation of tubulin deacetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation.
GO:1904429	regulation of t-circle formation	biological_process	Any process that modulates the frequency, rate or extent of t-circle formation.
GO:1904430	negative regulation of t-circle formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
GO:1904431	positive regulation of t-circle formation	biological_process	Any process that activates or increases the frequency, rate or extent of t-circle formation.
GO:1904432	regulation of ferrous iron binding	biological_process	Any process that modulates the frequency, rate or extent of ferrous iron binding.
GO:1904433	negative regulation of ferrous iron binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding.
GO:1904434	positive regulation of ferrous iron binding	biological_process	Any process that activates or increases the frequency, rate or extent of ferrous iron binding.
GO:1904435	regulation of transferrin receptor binding	biological_process	Any process that modulates the frequency, rate or extent of transferrin receptor binding.
GO:1904436	negative regulation of transferrin receptor binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding.
GO:1904437	positive regulation of transferrin receptor binding	biological_process	Any process that activates or increases the frequency, rate or extent of transferrin receptor binding.
GO:1904438	regulation of iron ion import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.
GO:1904439	negative regulation of iron ion import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.
GO:1904440	positive regulation of iron ion import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.
GO:1904441	regulation of thyroid gland epithelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation.
GO:1904442	negative regulation of thyroid gland epithelial cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.
GO:1904443	positive regulation of thyroid gland epithelial cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation.
GO:1904444	regulation of establishment of Sertoli cell barrier	biological_process	Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier.
GO:1904445	negative regulation of establishment of Sertoli cell barrier	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.
GO:1904446	positive regulation of establishment of Sertoli cell barrier	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.
GO:1904447	folate import across plasma membrane	biological_process	The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol.
GO:1904448	regulation of aspartate secretion	biological_process	Any process that modulates the frequency, rate or extent of aspartate secretion.
GO:1904449	negative regulation of aspartate secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.
GO:1904450	positive regulation of aspartate secretion	biological_process	Any process that activates or increases the frequency, rate or extent of aspartate secretion.
GO:1904451	regulation of potassium:proton exchanging ATPase activity	biological_process	Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
GO:1904452	negative regulation of potassium:proton exchanging ATPase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
GO:1904453	positive regulation of potassium:proton exchanging ATPase activity	biological_process	Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
GO:1904456	negative regulation of neuronal action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.
GO:1904457	positive regulation of neuronal action potential	biological_process	Any process that activates or increases the frequency, rate or extent of neuronal action potential.
GO:1904458	regulation of substance P secretion	biological_process	Any process that modulates the frequency, rate or extent of substance P secretion.
GO:1904459	negative regulation of substance P secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.
GO:1904460	positive regulation of substance P secretion	biological_process	Any process that activates or increases the frequency, rate or extent of substance P secretion.
GO:1904461	ergosteryl 3-beta-D-glucoside metabolic process	biological_process	The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside.
GO:1904462	ergosteryl 3-beta-D-glucoside catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.
GO:1904463	ergosteryl 3-beta-D-glucoside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.
GO:1904464	regulation of matrix metallopeptidase secretion	biological_process	Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.
GO:1904465	negative regulation of matrix metallopeptidase secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.
GO:1904466	positive regulation of matrix metallopeptidase secretion	biological_process	Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.
GO:1904470	regulation of endothelin production	biological_process	Any process that modulates the frequency, rate or extent of endothelin production.
GO:1904471	negative regulation of endothelin production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production.
GO:1904472	positive regulation of endothelin production	biological_process	Any process that activates or increases the frequency, rate or extent of endothelin production.
GO:1904473	response to L-dopa	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.
GO:1904474	cellular response to L-dopa	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.
GO:1904475	regulation of small GTPase binding	biological_process	Any process that modulates the frequency, rate or extent of small GTPase binding.
GO:1904476	negative regulation of small GTPase binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding.
GO:1904477	positive regulation of small GTPase binding	biological_process	Any process that activates or increases the frequency, rate or extent of small GTPase binding.
GO:1904478	regulation of intestinal absorption	biological_process	Any process that modulates the frequency, rate or extent of intestinal absorption.
GO:1904479	negative regulation of intestinal absorption	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.
GO:1904480	positive regulation of intestinal absorption	biological_process	Any process that activates or increases the frequency, rate or extent of intestinal absorption.
GO:1904481	response to tetrahydrofolate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.
GO:1904482	cellular response to tetrahydrofolate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.
GO:1904483	synthetic cannabinoid binding	molecular_function	Binding to synthetic cannabinoid.
GO:1904484	cloacal gland development	biological_process	The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.
GO:1904491	protein localization to ciliary transition zone	biological_process	A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.
GO:1904492	Ac-Asp-Glu binding	molecular_function	Binding to Ac-Asp-Glu.
GO:1904493	tetrahydrofolyl-poly(glutamate) polymer binding	molecular_function	Binding to tetrahydrofolyl-poly(glutamate) polymer.
GO:1904494	regulation of substance P secretion, neurotransmission	biological_process	Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission.
GO:1904495	negative regulation of substance P secretion, neurotransmission	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.
GO:1904496	positive regulation of substance P secretion, neurotransmission	biological_process	Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.
GO:1904498	protein localization to mitotic actomyosin contractile ring	biological_process	Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.
GO:1904502	regulation of lipophagy	biological_process	Any process that modulates the frequency, rate or extent of lipophagy.
GO:1904503	negative regulation of lipophagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.
GO:1904504	positive regulation of lipophagy	biological_process	Any process that activates or increases the frequency, rate or extent of lipophagy.
GO:1904505	regulation of telomere maintenance in response to DNA damage	biological_process	Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.
GO:1904506	negative regulation of telomere maintenance in response to DNA damage	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.
GO:1904507	positive regulation of telomere maintenance in response to DNA damage	biological_process	Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.
GO:1904508	regulation of protein localization to basolateral plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.
GO:1904509	negative regulation of protein localization to basolateral plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.
GO:1904510	positive regulation of protein localization to basolateral plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.
GO:1904511	cytoplasmic microtubule plus-end	cellular_component	Any microtubule plus-end that is part of a cytoplasmic microtubule.
GO:1904512	regulation of initiation of premeiotic DNA replication	biological_process	Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.
GO:1904513	negative regulation of initiation of premeiotic DNA replication	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.
GO:1904514	positive regulation of initiation of premeiotic DNA replication	biological_process	Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.
GO:1904515	positive regulation of TORC2 signaling	biological_process	Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
GO:1904516	myofibroblast cell apoptotic process	biological_process	Any apoptotic process in a myofibroblast cell.
GO:1904518	protein localization to cytoplasmic microtubule plus-end	biological_process	A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.
GO:1904519	protein localization to microtubule minus-end	biological_process	A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.
GO:1904520	regulation of myofibroblast cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.
GO:1904521	negative regulation of myofibroblast cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process.
GO:1904522	positive regulation of myofibroblast cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process.
GO:1904523	regulation of DNA amplification	biological_process	Any process that modulates the frequency, rate or extent of DNA amplification.
GO:1904524	negative regulation of DNA amplification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.
GO:1904525	positive regulation of DNA amplification	biological_process	Any process that activates or increases the frequency, rate or extent of DNA amplification.
GO:1904526	regulation of microtubule binding	biological_process	Any process that modulates the frequency, rate or extent of microtubule binding.
GO:1904527	negative regulation of microtubule binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.
GO:1904528	positive regulation of microtubule binding	biological_process	Any process that activates or increases the frequency, rate or extent of microtubule binding.
GO:1904529	regulation of actin filament binding	biological_process	Any process that modulates the frequency, rate or extent of actin filament binding.
GO:1904530	negative regulation of actin filament binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.
GO:1904531	positive regulation of actin filament binding	biological_process	Any process that activates or increases the frequency, rate or extent of actin filament binding.
GO:1904533	regulation of telomeric loop disassembly	biological_process	Any process that modulates the frequency, rate or extent of telomeric loop disassembly.
GO:1904534	negative regulation of telomeric loop disassembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.
GO:1904535	positive regulation of telomeric loop disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.
GO:1904536	regulation of mitotic telomere tethering at nuclear periphery	biological_process	Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.
GO:1904537	negative regulation of mitotic telomere tethering at nuclear periphery	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.
GO:1904538	regulation of glycolytic process through fructose-6-phosphate	biological_process	Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
GO:1904539	negative regulation of glycolytic process through fructose-6-phosphate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
GO:1904540	positive regulation of glycolytic process through fructose-6-phosphate	biological_process	Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
GO:1904541	fungal-type cell wall disassembly involved in conjugation with cellular fusion	biological_process	Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion.
GO:1904542	regulation of free ubiquitin chain polymerization	biological_process	Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.
GO:1904543	negative regulation of free ubiquitin chain polymerization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization.
GO:1904544	positive regulation of free ubiquitin chain polymerization	biological_process	Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.
GO:1904547	regulation of cellular response to glucose starvation	biological_process	Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.
GO:1904550	response to arachidonic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.
GO:1904551	cellular response to arachidonic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.
GO:1904552	regulation of chemotaxis to arachidonic acid	biological_process	Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid.
GO:1904553	negative regulation of chemotaxis to arachidonic acid	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid.
GO:1904554	positive regulation of chemotaxis to arachidonic acid	biological_process	Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.
GO:1904555	L-proline transmembrane transport	biological_process	The directed movement of L-proline across a membrane.
GO:1904556	L-tryptophan transmembrane transport	biological_process	The directed movement of L-tryptophan across a membrane.
GO:1904557	L-alanine transmembrane transport	biological_process	The directed movement of L-alanine across a membrane.
GO:1904558	response to dextromethorphan	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.
GO:1904559	cellular response to dextromethorphan	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.
GO:1904560	response to diphenidol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.
GO:1904561	cellular response to diphenidol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.
GO:1904562	phosphatidylinositol 5-phosphate metabolic process	biological_process	The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.
GO:1904563	phosphatidylinositol 5-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate.
GO:1904564	Nbp35-Cfd1 ATPase complex	cellular_component	An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1.
GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.
GO:1904566	cellular response to 1-oleoyl-sn-glycerol 3-phosphate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.
GO:1904567	response to wortmannin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.
GO:1904568	cellular response to wortmannin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.
GO:1904569	regulation of selenocysteine incorporation	biological_process	Any process that modulates the frequency, rate or extent of selenocysteine incorporation.
GO:1904570	negative regulation of selenocysteine incorporation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation.
GO:1904571	positive regulation of selenocysteine incorporation	biological_process	Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation.
GO:1904572	negative regulation of mRNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.
GO:1904573	regulation of selenocysteine insertion sequence binding	biological_process	Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding.
GO:1904574	negative regulation of selenocysteine insertion sequence binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding.
GO:1904575	positive regulation of selenocysteine insertion sequence binding	biological_process	Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding.
GO:1904580	regulation of intracellular mRNA localization	biological_process	Any process that modulates the frequency, rate or extent of intracellular mRNA localization.
GO:1904581	negative regulation of intracellular mRNA localization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.
GO:1904582	positive regulation of intracellular mRNA localization	biological_process	Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
GO:1904583	response to polyamine macromolecule	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.
GO:1904584	cellular response to polyamine macromolecule	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.
GO:1904585	response to putrescine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.
GO:1904586	cellular response to putrescine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.
GO:1904587	response to glycoprotein	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.
GO:1904588	cellular response to glycoprotein	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.
GO:1904589	regulation of protein import	biological_process	Any process that modulates the frequency, rate or extent of protein import.
GO:1904590	negative regulation of protein import	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein import.
GO:1904591	positive regulation of protein import	biological_process	Any process that activates or increases the frequency, rate or extent of protein import.
GO:1904592	positive regulation of protein refolding	biological_process	Any process that activates or increases the frequency, rate or extent of protein refolding.
GO:1904593	prostaglandin binding	molecular_function	Binding to prostaglandin.
GO:1904594	regulation of termination of RNA polymerase II transcription	biological_process	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.
GO:1904595	positive regulation of termination of RNA polymerase II transcription	biological_process	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.
GO:1904596	regulation of connective tissue replacement involved in inflammatory response wound healing	biological_process	Any process that modulates the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response.
GO:1904597	negative regulation of connective tissue replacement involved in inflammatory response wound healing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response.
GO:1904598	positive regulation of connective tissue replacement involved in inflammatory response wound healing	biological_process	Any process that activates or increases the frequency, rate or extent of wound healing connective tissue replacement, which may be replaced with fibrotic material, that occurs as part of an inflammatory response.
GO:1904599	advanced glycation end-product binding	molecular_function	Binding to advanced glycation end-product.
GO:1904600	mating projection actin fusion focus assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus.
GO:1904601	protein transport to mating projection actin fusion focus	biological_process	A process in which a protein is transported to a location within an actin fusion focus.
GO:1904602	serotonin-activated cation-selective channel complex	cellular_component	A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.
GO:1904603	regulation of advanced glycation end-product receptor activity	biological_process	Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity.
GO:1904604	negative regulation of advanced glycation end-product receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity.
GO:1904605	positive regulation of advanced glycation end-product receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity.
GO:1904606	fat cell apoptotic process	biological_process	Any apoptotic process in a fat cell.
GO:1904610	response to 3,3',4,4',5-pentachlorobiphenyl	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.
GO:1904611	cellular response to 3,3',4,4',5-pentachlorobiphenyl	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.
GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.
GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.
GO:1904614	response to biphenyl	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.
GO:1904615	cellular response to biphenyl	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.
GO:1904616	regulation of actin binding	biological_process	Any process that modulates the frequency, rate or extent of actin binding.
GO:1904617	negative regulation of actin binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of actin binding.
GO:1904618	positive regulation of actin binding	biological_process	Any process that activates or increases the frequency, rate or extent of actin binding.
GO:1904619	response to dimethyl sulfoxide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.
GO:1904620	cellular response to dimethyl sulfoxide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.
GO:1904624	regulation of glycine secretion, neurotransmission	biological_process	Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission.
GO:1904625	negative regulation of glycine secretion, neurotransmission	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.
GO:1904626	positive regulation of glycine secretion, neurotransmission	biological_process	Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission.
GO:1904627	response to phorbol 13-acetate 12-myristate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.
GO:1904628	cellular response to phorbol 13-acetate 12-myristate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.
GO:1904629	response to diterpene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.
GO:1904630	cellular response to diterpene	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.
GO:1904631	response to glucoside	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.
GO:1904632	cellular response to glucoside	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.
GO:1904633	regulation of podocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
GO:1904634	negative regulation of podocyte apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
GO:1904635	positive regulation of podocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
GO:1904636	response to ionomycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.
GO:1904637	cellular response to ionomycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.
GO:1904638	response to resveratrol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.
GO:1904639	cellular response to resveratrol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.
GO:1904640	response to methionine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.
GO:1904641	response to dinitrophenol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.
GO:1904642	cellular response to dinitrophenol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.
GO:1904643	response to curcumin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
GO:1904644	cellular response to curcumin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
GO:1904645	response to amyloid-beta	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
GO:1904646	cellular response to amyloid-beta	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
GO:1904647	response to rotenone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.
GO:1904648	cellular response to rotenone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.
GO:1904649	regulation of fat cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of fat cell apoptotic process.
GO:1904650	negative regulation of fat cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.
GO:1904651	positive regulation of fat cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.
GO:1904652	protein localization to cell division site involved in cell separation after cytokinesis	biological_process	Any protein localization to cell division site that is involved in cell separation after cytokinesis.
GO:1904653	regulation of lung alveolus development	biological_process	Any process that modulates the frequency, rate or extent of lung alveolus development.
GO:1904654	negative regulation of lung alveolus development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.
GO:1904655	positive regulation of lung alveolus development	biological_process	Any process that activates or increases the frequency, rate or extent of lung alveolus development.
GO:1904656	regulation of sensory perception of sweet taste	biological_process	Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.
GO:1904657	negative regulation of sensory perception of sweet taste	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste.
GO:1904658	positive regulation of sensory perception of sweet taste	biological_process	Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.
GO:1904659	glucose transmembrane transport	biological_process	The process in which glucose is transported across a membrane.
GO:1904660	regulation of sensory perception of bitter taste	biological_process	Any process that modulates the frequency, rate or extent of sensory perception of bitter taste.
GO:1904661	negative regulation of sensory perception of bitter taste	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.
GO:1904662	positive regulation of sensory perception of bitter taste	biological_process	Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste.
GO:1904663	regulation of N-terminal peptidyl-methionine acetylation	biological_process	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
GO:1904664	negative regulation of N-terminal peptidyl-methionine acetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
GO:1904665	positive regulation of N-terminal peptidyl-methionine acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
GO:1904666	regulation of ubiquitin protein ligase activity	biological_process	Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity.
GO:1904667	negative regulation of ubiquitin protein ligase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.
GO:1904668	positive regulation of ubiquitin protein ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
GO:1904669	ATP export	biological_process	The directed movement of ATP out of a cell or organelle.
GO:1904671	negative regulation of cell differentiation involved in stem cell population maintenance	biological_process	Any negative regulation of cell differentiation that is involved in stem cell population maintenance.
GO:1904672	regulation of somatic stem cell population maintenance	biological_process	Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.
GO:1904673	negative regulation of somatic stem cell population maintenance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.
GO:1904674	positive regulation of somatic stem cell population maintenance	biological_process	Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.
GO:1904675	regulation of somatic stem cell division	biological_process	Any process that modulates the frequency, rate or extent of somatic stem cell division.
GO:1904676	negative regulation of somatic stem cell division	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.
GO:1904677	positive regulation of somatic stem cell division	biological_process	Any process that activates or increases the frequency, rate or extent of somatic stem cell division.
GO:1904678	alpha-aminoacyl-tRNA binding	molecular_function	Binding to an alpha-aminoacyl-tRNA.
GO:1904679	myo-inositol import across plasma membrane	biological_process	The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol.
GO:1904680	peptide transmembrane transporter activity	molecular_function	Enables the transfer of a peptide from one side of a membrane to the other.
GO:1904681	response to 3-methylcholanthrene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.
GO:1904682	cellular response to 3-methylcholanthrene	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.
GO:1904683	regulation of metalloendopeptidase activity	biological_process	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity.
GO:1904684	negative regulation of metalloendopeptidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity.
GO:1904685	positive regulation of metalloendopeptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity.
GO:1904686	regulation of mitotic spindle disassembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.
GO:1904687	positive regulation of mitotic spindle disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.
GO:1904688	regulation of cytoplasmic translational initiation	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.
GO:1904689	negative regulation of cytoplasmic translational initiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.
GO:1904690	positive regulation of cytoplasmic translational initiation	biological_process	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.
GO:1904691	negative regulation of type B pancreatic cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.
GO:1904692	positive regulation of type B pancreatic cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.
GO:1904693	midbrain morphogenesis	biological_process	The developmental process by which a midbrain is generated and organized.
GO:1904694	negative regulation of vascular associated smooth muscle contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction.
GO:1904695	positive regulation of vascular associated smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction.
GO:1904697	regulation of acinar cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of acinar cell proliferation.
GO:1904698	negative regulation of acinar cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.
GO:1904699	positive regulation of acinar cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.
GO:1904700	granulosa cell apoptotic process	biological_process	Any apoptotic process in a granulosa cell.
GO:1904701	Wnt-Frizzled-LRP5/6 complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.
GO:1904702	regulation of protein localization to adherens junction	biological_process	Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:1904703	negative regulation of protein localization to adherens junction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:1904704	positive regulation of protein localization to adherens junction	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
GO:1904708	regulation of granulosa cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.
GO:1904709	negative regulation of granulosa cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.
GO:1904710	positive regulation of granulosa cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.
GO:1904711	regulation of Wnt-Frizzled-LRP5/6 complex assembly	biological_process	Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
GO:1904712	positive regulation of Wnt-Frizzled-LRP5/6 complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
GO:1904713	beta-catenin destruction complex binding	molecular_function	Binding to a beta-catenin destruction complex.
GO:1904714	regulation of chaperone-mediated autophagy	biological_process	Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy.
GO:1904715	negative regulation of chaperone-mediated autophagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy.
GO:1904716	positive regulation of chaperone-mediated autophagy	biological_process	Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.
GO:1904717	regulation of AMPA glutamate receptor clustering	biological_process	Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.
GO:1904718	negative regulation of AMPA glutamate receptor clustering	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering.
GO:1904719	positive regulation of AMPA glutamate receptor clustering	biological_process	Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.
GO:1904723	negative regulation of Wnt-Frizzled-LRP5/6 complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
GO:1904724	tertiary granule lumen	cellular_component	Any membrane-enclosed lumen that is part of a tertiary granule.
GO:1904726	regulation of replicative senescence	biological_process	Any process that modulates the frequency, rate or extent of replicative senescence.
GO:1904727	negative regulation of replicative senescence	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence.
GO:1904728	positive regulation of replicative senescence	biological_process	Any process that activates or increases the frequency, rate or extent of replicative senescence.
GO:1904729	regulation of intestinal lipid absorption	biological_process	Any process that modulates the frequency, rate or extent of intestinal lipid absorption.
GO:1904730	negative regulation of intestinal lipid absorption	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption.
GO:1904731	positive regulation of intestinal lipid absorption	biological_process	Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.
GO:1904732	regulation of electron transfer activity	biological_process	Any process that modulates the frequency, rate or extent of electron transfer activity.
GO:1904733	negative regulation of electron transfer activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity.
GO:1904734	positive regulation of electron transfer activity	biological_process	Any process that activates or increases the frequency, rate or extent of electron transfer activity.
GO:1904735	regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	biological_process	Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
GO:1904736	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
GO:1904737	positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	biological_process	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
GO:1904738	vascular associated smooth muscle cell migration	biological_process	The orderly movement of a vascular associated smooth muscle cell from one site to another.
GO:1904742	regulation of telomeric DNA binding	biological_process	Any process that modulates the frequency, rate or extent of telomeric DNA binding.
GO:1904743	negative regulation of telomeric DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.
GO:1904744	positive regulation of telomeric DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of telomeric DNA binding.
GO:1904745	Atg1/ULK1 kinase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.
GO:1904746	negative regulation of apoptotic process involved in development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.
GO:1904747	positive regulation of apoptotic process involved in development	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.
GO:1904748	regulation of apoptotic process involved in development	biological_process	Any process that modulates the frequency, rate or extent of apoptotic process involved in development.
GO:1904749	regulation of protein localization to nucleolus	biological_process	Any process that modulates the frequency, rate or extent of protein localization to nucleolus.
GO:1904750	negative regulation of protein localization to nucleolus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.
GO:1904751	positive regulation of protein localization to nucleolus	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.
GO:1904752	regulation of vascular associated smooth muscle cell migration	biological_process	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
GO:1904755	regulation of gut granule assembly	biological_process	Any process that modulates the frequency, rate or extent of gut granule assembly.
GO:1904756	negative regulation of gut granule assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.
GO:1904757	positive regulation of gut granule assembly	biological_process	Any process that activates or increases the frequency, rate or extent of gut granule assembly.
GO:1904758	protein localization to new growing cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.
GO:1904759	protein localization to equatorial microtubule organizing center	biological_process	A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.
GO:1904760	regulation of myofibroblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of myofibroblast differentiation.
GO:1904761	negative regulation of myofibroblast differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.
GO:1904762	positive regulation of myofibroblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation.
GO:1904763	chaperone-mediated autophagy translocation complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex.
GO:1904764	chaperone-mediated autophagy translocation complex disassembly	biological_process	The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.
GO:1904767	octanoic acid binding	molecular_function	Binding to octanoic acid.
GO:1904768	all-trans-retinol binding	molecular_function	Binding to all-trans-retinol.
GO:1904769	isopentadecanoic acid binding	molecular_function	Binding to isopentadecanoic acid.
GO:1904770	intramembranous bone morphogenesis	biological_process	The developmental process by which an intramembranous bone is generated and organized.
GO:1904772	response to tetrachloromethane	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.
GO:1904774	negative regulation of ubiquinone biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process.
GO:1904775	positive regulation of ubiquinone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process.
GO:1904776	regulation of protein localization to cell cortex	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell cortex.
GO:1904777	negative regulation of protein localization to cell cortex	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.
GO:1904778	positive regulation of protein localization to cell cortex	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.
GO:1904779	regulation of protein localization to centrosome	biological_process	Any process that modulates the frequency, rate or extent of protein localization to centrosome.
GO:1904780	negative regulation of protein localization to centrosome	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.
GO:1904781	positive regulation of protein localization to centrosome	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.
GO:1904782	negative regulation of NMDA glutamate receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.
GO:1904783	positive regulation of NMDA glutamate receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity.
GO:1904784	NLRP1 inflammasome complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.
GO:1904785	regulation of asymmetric protein localization involved in cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
GO:1904786	negative regulation of asymmetric protein localization involved in cell fate determination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
GO:1904787	positive regulation of asymmetric protein localization involved in cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
GO:1904790	regulation of shelterin complex assembly	biological_process	Any process that modulates the frequency, rate or extent of shelterin complex assembly.
GO:1904791	negative regulation of shelterin complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly.
GO:1904792	positive regulation of shelterin complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of shelterin complex assembly.
GO:1904793	regulation of euchromatin binding	biological_process	Any process that modulates the frequency, rate or extent of euchromatin binding.
GO:1904794	negative regulation of euchromatin binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.
GO:1904795	positive regulation of euchromatin binding	biological_process	Any process that activates or increases the frequency, rate or extent of euchromatin binding.
GO:1904796	regulation of core promoter binding	biological_process	Any process that modulates the frequency, rate or extent of core promoter binding.
GO:1904797	negative regulation of core promoter binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.
GO:1904798	positive regulation of core promoter binding	biological_process	Any process that activates or increases the frequency, rate or extent of core promoter binding.
GO:1904799	regulation of neuron remodeling	biological_process	Any process that modulates the frequency, rate or extent of neuron remodeling.
GO:1904800	negative regulation of neuron remodeling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling.
GO:1904801	positive regulation of neuron remodeling	biological_process	Any process that activates or increases the frequency, rate or extent of neuron remodeling.
GO:1904802	RITS complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a RITS complex.
GO:1904803	regulation of translation involved in cellular response to UV	biological_process	Any regulation of translation that is involved in cellular response to UV.
GO:1904806	regulation of protein oxidation	biological_process	Any process that modulates the frequency, rate or extent of protein oxidation.
GO:1904807	negative regulation of protein oxidation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation.
GO:1904808	positive regulation of protein oxidation	biological_process	Any process that activates or increases the frequency, rate or extent of protein oxidation.
GO:1904809	regulation of dense core granule transport	biological_process	Any process that modulates the frequency, rate or extent of dense core granule transport.
GO:1904810	negative regulation of dense core granule transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.
GO:1904811	positive regulation of dense core granule transport	biological_process	Any process that activates or increases the frequency, rate or extent of dense core granule transport.
GO:1904812	rRNA acetylation involved in maturation of SSU-rRNA	biological_process	Any rRNA acetylation that is involved in maturation of SSU-rRNA.
GO:1904813	ficolin-1-rich granule lumen	cellular_component	Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
GO:1904814	regulation of protein localization to chromosome, telomeric region	biological_process	Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region.
GO:1904815	negative regulation of protein localization to chromosome, telomeric region	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region.
GO:1904816	positive regulation of protein localization to chromosome, telomeric region	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region.
GO:1904817	serous membrane development	biological_process	The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.
GO:1904818	visceral peritoneum development	biological_process	The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.
GO:1904819	parietal peritoneum development	biological_process	The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.
GO:1904820	peritoneum development	biological_process	The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.
GO:1904821	chloroplast disassembly	biological_process	The disaggregation of a chloroplast into its constituent components.
GO:1904823	purine nucleobase transmembrane transport	biological_process	The process in which a purine nucleobase is transported across a membrane.
GO:1904824	anaphase-promoting complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex.
GO:1904825	protein localization to microtubule plus-end	biological_process	A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.
GO:1904826	regulation of hydrogen sulfide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.
GO:1904827	negative regulation of hydrogen sulfide biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.
GO:1904828	positive regulation of hydrogen sulfide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.
GO:1904829	regulation of aortic smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.
GO:1904830	negative regulation of aortic smooth muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.
GO:1904831	positive regulation of aortic smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.
GO:1904832	negative regulation of removal of superoxide radicals	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.
GO:1904833	positive regulation of removal of superoxide radicals	biological_process	Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.
GO:1904835	dorsal root ganglion morphogenesis	biological_process	The developmental process by which a dorsal root ganglion is generated and organized.
GO:1904836	facioacoustic ganglion morphogenesis	biological_process	The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.
GO:1904837	beta-catenin-TCF complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.
GO:1904838	regulation of male germ-line stem cell asymmetric division	biological_process	Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.
GO:1904839	negative regulation of male germ-line stem cell asymmetric division	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.
GO:1904840	positive regulation of male germ-line stem cell asymmetric division	biological_process	Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division.
GO:1904841	TORC2 complex binding	molecular_function	Binding to a TORC2 complex.
GO:1904842	response to nitroglycerin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.
GO:1904843	cellular response to nitroglycerin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.
GO:1904844	response to L-glutamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.
GO:1904845	cellular response to L-glutamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.
GO:1904846	negative regulation of establishment of bipolar cell polarity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity.
GO:1904847	regulation of cell chemotaxis to fibroblast growth factor	biological_process	Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
GO:1904848	negative regulation of cell chemotaxis to fibroblast growth factor	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor	biological_process	Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
GO:1904850	negative regulation of establishment of protein localization to telomere	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.
GO:1904851	positive regulation of establishment of protein localization to telomere	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.
GO:1904852	trimethylamine-N-oxide reductase (cytochrome c) complex	cellular_component	A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity.
GO:1904853	protein localization to ascospore wall	biological_process	A process in which a protein is transported to, or maintained in, a location within an ascospore wall.
GO:1904854	proteasome core complex binding	molecular_function	Binding to a proteasome core complex.
GO:1904855	proteasome regulatory particle binding	molecular_function	Binding to a proteasome regulatory particle.
GO:1904856	cytolytic granule lumen	cellular_component	Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule.
GO:1904857	regulation of endothelial cell chemotaxis to vascular endothelial growth factor	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
GO:1904858	negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
GO:1904859	positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
GO:1904860	DNA synthesis involved in mitotic DNA replication	biological_process	Any DNA biosynthetic process that is involved in mitotic DNA replication.
GO:1904861	excitatory synapse assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
GO:1904862	inhibitory synapse assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.
GO:1904863	regulation of beta-catenin-TCF complex assembly	biological_process	Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.
GO:1904864	negative regulation of beta-catenin-TCF complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly.
GO:1904865	positive regulation of beta-catenin-TCF complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.
GO:1904866	ventral tegmental area development	biological_process	The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.
GO:1904867	protein localization to Cajal body	biological_process	A process in which a protein is transported to, or maintained in, a location within a Cajal body.
GO:1904868	telomerase catalytic core complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.
GO:1904869	regulation of protein localization to Cajal body	biological_process	Any process that modulates the frequency, rate or extent of protein localization to Cajal body.
GO:1904870	negative regulation of protein localization to Cajal body	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.
GO:1904871	positive regulation of protein localization to Cajal body	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.
GO:1904872	regulation of telomerase RNA localization to Cajal body	biological_process	Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.
GO:1904873	negative regulation of telomerase RNA localization to Cajal body	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	biological_process	Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
GO:1904875	regulation of DNA ligase activity	biological_process	Any process that modulates the frequency, rate or extent of DNA ligase activity.
GO:1904876	negative regulation of DNA ligase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.
GO:1904877	positive regulation of DNA ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of DNA ligase activity.
GO:1904878	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.
GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.
GO:1904880	response to hydrogen sulfide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.
GO:1904881	cellular response to hydrogen sulfide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.
GO:1904882	regulation of telomerase catalytic core complex assembly	biological_process	Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly.
GO:1904883	negative regulation of telomerase catalytic core complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.
GO:1904884	positive regulation of telomerase catalytic core complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly.
GO:1904885	beta-catenin destruction complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.
GO:1904886	beta-catenin destruction complex disassembly	biological_process	The disaggregation of a beta-catenin destruction complex into its constituent components.
GO:1904887	Wnt signalosome assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome.
GO:1904888	cranial skeletal system development	biological_process	The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.
GO:1904889	regulation of excitatory synapse assembly	biological_process	Any process that modulates the frequency, rate or extent of excitatory synapse assembly.
GO:1904890	negative regulation of excitatory synapse assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.
GO:1904891	positive regulation of excitatory synapse assembly	biological_process	Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.
GO:1904892	regulation of receptor signaling pathway via STAT	biological_process	Any process that modulates the frequency, rate or extent of receptor signaling via STAT.
GO:1904893	negative regulation of receptor signaling pathway via STAT	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.
GO:1904894	positive regulation of receptor signaling pathway via STAT	biological_process	Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.
GO:1904895	ESCRT complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex.
GO:1904896	ESCRT complex disassembly	biological_process	The disaggregation of an ESCRT complex into its constituent components.
GO:1904897	regulation of hepatic stellate cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.
GO:1904898	negative regulation of hepatic stellate cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.
GO:1904899	positive regulation of hepatic stellate cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
GO:1904900	negative regulation of myosin II filament organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization.
GO:1904901	positive regulation of myosin II filament organization	biological_process	Any process that activates or increases the frequency, rate or extent of myosin II filament organization.
GO:1904902	ESCRT III complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex.
GO:1904903	ESCRT III complex disassembly	biological_process	The disaggregation of an ESCRT III complex into its constituent components.
GO:1904904	regulation of endothelial cell-matrix adhesion via fibronectin	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
GO:1904905	negative regulation of endothelial cell-matrix adhesion via fibronectin	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
GO:1904906	positive regulation of endothelial cell-matrix adhesion via fibronectin	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
GO:1904907	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	biological_process	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
GO:1904908	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
GO:1904909	positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric	biological_process	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
GO:1904910	regulation of establishment of RNA localization to telomere	biological_process	Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.
GO:1904911	negative regulation of establishment of RNA localization to telomere	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere.
GO:1904912	positive regulation of establishment of RNA localization to telomere	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere.
GO:1904913	regulation of establishment of protein-containing complex localization to telomere	biological_process	Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.
GO:1904914	negative regulation of establishment of protein-containing complex localization to telomere	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.
GO:1904915	positive regulation of establishment of protein-containing complex localization to telomere	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.
GO:1904916	transmembrane L-lysine transport from lysosomal lumen to cytosol	biological_process	The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol.
GO:1904917	L-arginine transmembrane transport from lysosomal lumen to cytosol	biological_process	The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol.
GO:1904918	transmembrane L-histidine transport from lysosomal lumen to cytosol	biological_process	The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol.
GO:1904919	transmembrane L-cystine transport from lysosomal lumen to cytosol	biological_process	The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol.
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	biological_process	Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization.
GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.
GO:1904926	response to palmitoleic acid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.
GO:1904927	cellular response to palmitoleic acid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.
GO:1904930	amphisome membrane	cellular_component	Any membrane that is part of an amphisome.
GO:1904931	MCM complex binding	molecular_function	Binding to an MCM complex.
GO:1904932	negative regulation of cartilage condensation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.
GO:1904933	regulation of cell proliferation in midbrain	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.
GO:1904934	negative regulation of cell proliferation in midbrain	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.
GO:1904935	positive regulation of cell proliferation in midbrain	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.
GO:1904936	interneuron migration	biological_process	The orderly movement of an interneuron from one site to another.
GO:1904937	sensory neuron migration	biological_process	The orderly movement of a sensory neuron from one site to another.
GO:1904938	planar cell polarity pathway involved in axon guidance	biological_process	Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.
GO:1904942	regulation of cardiac ventricle formation	biological_process	Any process that modulates the frequency, rate or extent of cardiac ventricle formation.
GO:1904943	negative regulation of cardiac ventricle formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.
GO:1904944	positive regulation of cardiac ventricle formation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.
GO:1904947	folate import into mitochondrion	biological_process	The process in which folic acid is transported from the cytosol into the mitochondrial matrix.
GO:1904948	midbrain dopaminergic neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.
GO:1904949	ATPase complex	cellular_component	A protein complex which is capable of ATPase activity.
GO:1904950	negative regulation of establishment of protein localization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.
GO:1904951	positive regulation of establishment of protein localization	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of protein localization.
GO:1904952	hydroxycinnamic acid transport	biological_process	The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	biological_process	Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	biological_process	Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
GO:1904955	planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation	biological_process	Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation.
GO:1904956	regulation of midbrain dopaminergic neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
GO:1904957	negative regulation of midbrain dopaminergic neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
GO:1904958	positive regulation of midbrain dopaminergic neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
GO:1904959	regulation of cytochrome-c oxidase activity	biological_process	Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.
GO:1904960	positive regulation of cytochrome-c oxidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
GO:1904961	quiescent center organization	biological_process	The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.
GO:1904962	plastid to vacuole vesicle-mediated transport	biological_process	The vesicle-mediated and directed movement of substances from plastid to vacuole.
GO:1904963	regulation of phytol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phytol biosynthetic process.
GO:1904964	positive regulation of phytol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.
GO:1904965	regulation of vitamin E biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process.
GO:1904966	positive regulation of vitamin E biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.
GO:1904967	regulation of spindle attachment to meiosis I kinetochore	biological_process	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.
GO:1904968	positive regulation of spindle attachment to meiosis I kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.
GO:1904969	slow muscle cell migration	biological_process	The orderly movement of a slow muscle cell from one site to another.
GO:1904970	brush border assembly	biological_process	The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.
GO:1904971	regulation of viral translation	biological_process	Any process that modulates the frequency, rate or extent of viral translation.
GO:1904972	negative regulation of viral translation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.
GO:1904973	positive regulation of viral translation	biological_process	Any process that activates or increases the frequency, rate or extent of viral translation.
GO:1904974	heparanase complex	cellular_component	A protein complex which is capable of heparanase activity.
GO:1904975	response to bleomycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.
GO:1904976	cellular response to bleomycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.
GO:1904977	lymphatic endothelial cell migration	biological_process	The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.
GO:1904978	regulation of endosome organization	biological_process	Any process that modulates the frequency, rate or extent of endosome organization.
GO:1904979	negative regulation of endosome organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.
GO:1904980	positive regulation of endosome organization	biological_process	Any process that activates or increases the frequency, rate or extent of endosome organization.
GO:1904981	maltose transmembrane transport	biological_process	The process in which maltose is transported across a membrane.
GO:1904982	sucrose transmembrane transport	biological_process	The process in which sucrose is transported across a membrane.
GO:1904983	glycine import into mitochondrion	biological_process	The process in which glycine is transported from the cytosol into the mitochondrial matrix.
GO:1904984	regulation of quinolinate biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.
GO:1904985	negative regulation of quinolinate biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process.
GO:1904986	positive regulation of quinolinate biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.
GO:1904987	regulation of endothelial cell activation	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell activation.
GO:1904988	negative regulation of endothelial cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.
GO:1904989	positive regulation of endothelial cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell activation.
GO:1904990	regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
GO:1904991	negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
GO:1904992	positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	biological_process	Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
GO:1904997	regulation of leukocyte adhesion to arterial endothelial cell	biological_process	Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
GO:1904998	negative regulation of leukocyte adhesion to arterial endothelial cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
GO:1904999	positive regulation of leukocyte adhesion to arterial endothelial cell	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
GO:1905001	negative regulation of membrane repolarization during atrial cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
GO:1905002	positive regulation of membrane repolarization during atrial cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
GO:1905003	picolinic acid metabolic process	biological_process	The chemical reactions and pathways involving picolinic acid.
GO:1905004	picolinic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of picolinic acid.
GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	biological_process	Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
GO:1905006	negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
GO:1905008	regulation of L-lysine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-lysine import into cell.
GO:1905009	negative regulation of L-lysine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.
GO:1905010	positive regulation of L-lysine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-lysine import into cell.
GO:1905011	transmembrane phosphate ion transport from cytosol to vacuole	biological_process	The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen.
GO:1905012	regulation of 'de novo' NAD biosynthetic process from tryptophan	biological_process	Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
GO:1905013	negative regulation of 'de novo' NAD biosynthetic process from tryptophan	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
GO:1905014	positive regulation of 'de novo' NAD biosynthetic process from tryptophan	biological_process	Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
GO:1905017	positive regulation of isoleucine-tRNA ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity.
GO:1905020	positive regulation of methionine-tRNA ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity.
GO:1905023	positive regulation of threonine-tRNA ligase activity	biological_process	Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity.
GO:1905024	regulation of membrane repolarization during ventricular cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
GO:1905025	negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
GO:1905026	positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
GO:1905027	regulation of membrane depolarization during AV node cell action potential	biological_process	Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.
GO:1905028	negative regulation of membrane depolarization during AV node cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.
GO:1905029	positive regulation of membrane depolarization during AV node cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential.
GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	molecular_function	Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
GO:1905031	regulation of membrane repolarization during cardiac muscle cell action potential	biological_process	Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
GO:1905032	negative regulation of membrane repolarization during cardiac muscle cell action potential	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
GO:1905033	positive regulation of membrane repolarization during cardiac muscle cell action potential	biological_process	Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
GO:1905034	regulation of antifungal innate immune response	biological_process	Any process that modulates the frequency, rate or extent of an antifungal innate immune response.
GO:1905035	negative regulation of antifungal innate immune response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.
GO:1905036	positive regulation of antifungal innate immune response	biological_process	Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.
GO:1905037	autophagosome organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.
GO:1905038	regulation of membrane lipid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.
GO:1905039	carboxylic acid transmembrane transport	biological_process	The process in which carboxylic acid is transported across a membrane.
GO:1905040	otic placode development	biological_process	The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.
GO:1905041	regulation of epithelium regeneration	biological_process	Any process that modulates the frequency, rate or extent of epithelium regeneration.
GO:1905042	negative regulation of epithelium regeneration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.
GO:1905043	positive regulation of epithelium regeneration	biological_process	Any process that activates or increases the frequency, rate or extent of epithelium regeneration.
GO:1905044	regulation of Schwann cell proliferation involved in axon regeneration	biological_process	Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
GO:1905045	negative regulation of Schwann cell proliferation involved in axon regeneration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
GO:1905046	positive regulation of Schwann cell proliferation involved in axon regeneration	biological_process	Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
GO:1905047	mitotic spindle pole body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.
GO:1905048	regulation of metallopeptidase activity	biological_process	Any process that modulates the frequency, rate or extent of metallopeptidase activity.
GO:1905049	negative regulation of metallopeptidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity.
GO:1905050	positive regulation of metallopeptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.
GO:1905051	regulation of base-excision repair	biological_process	Any process that modulates the frequency, rate or extent of base-excision repair.
GO:1905052	negative regulation of base-excision repair	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.
GO:1905053	positive regulation of base-excision repair	biological_process	Any process that activates or increases the frequency, rate or extent of base-excision repair.
GO:1905054	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration	molecular_function	Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.
GO:1905055	calcium:monoatomic cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	molecular_function	Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.
GO:1905056	P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	molecular_function	A calcium-transporting P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration.
GO:1905057	voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels	molecular_function	Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:1905058	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:1905059	P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:1905060	calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	molecular_function	Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
GO:1905061	negative regulation of cardioblast proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.
GO:1905062	positive regulation of cardioblast proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.
GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.
GO:1905066	regulation of canonical Wnt signaling pathway involved in heart development	biological_process	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
GO:1905067	negative regulation of canonical Wnt signaling pathway involved in heart development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development	biological_process	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
GO:1905069	allantois development	biological_process	The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.
GO:1905070	anterior visceral endoderm cell migration	biological_process	The orderly movement of an anterior visceral endoderm cell from one site to another.
GO:1905071	tight junction disassembly	biological_process	The disaggregation of an tight junction into its constituent components.
GO:1905072	cardiac jelly development	biological_process	The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart.
GO:1905073	regulation of tight junction disassembly	biological_process	Any process that modulates the frequency, rate or extent of tight junction disassembly.
GO:1905074	negative regulation of tight junction disassembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly.
GO:1905075	positive regulation of tight junction disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of tight junction disassembly.
GO:1905079	regulation of cerebellar neuron development	biological_process	Any process that modulates the frequency, rate or extent of cerebellar neuron development.
GO:1905080	negative regulation of cerebellar neuron development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.
GO:1905081	positive regulation of cerebellar neuron development	biological_process	Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.
GO:1905082	regulation of mitochondrial translational elongation	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.
GO:1905083	negative regulation of mitochondrial translational elongation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.
GO:1905084	positive regulation of mitochondrial translational elongation	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.
GO:1905085	regulation of bioluminescence	biological_process	Any process that modulates the frequency, rate or extent of bioluminescence.
GO:1905086	negative regulation of bioluminescence	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.
GO:1905087	positive regulation of bioluminescence	biological_process	Any process that activates or increases the frequency, rate or extent of bioluminescence.
GO:1905088	positive regulation of synaptonemal complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.
GO:1905089	regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological_process	Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization.
GO:1905090	negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.
GO:1905091	positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	biological_process	Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.
GO:1905092	response to diosgenin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.
GO:1905093	cellular response to diosgenin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.
GO:1905094	regulation of apolipoprotein A-I-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
GO:1905095	negative regulation of apolipoprotein A-I-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
GO:1905096	positive regulation of apolipoprotein A-I-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
GO:1905097	regulation of guanyl-nucleotide exchange factor activity	biological_process	Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
GO:1905099	positive regulation of guanyl-nucleotide exchange factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
GO:1905100	regulation of apoptosome assembly	biological_process	Any process that modulates the frequency, rate or extent of apoptosome assembly.
GO:1905101	negative regulation of apoptosome assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.
GO:1905102	positive regulation of apoptosome assembly	biological_process	Any process that activates or increases the frequency, rate or extent of apoptosome assembly.
GO:1905108	guanosine binding	molecular_function	Binding to guanosine.
GO:1905109	regulation of pulmonary blood vessel remodeling	biological_process	Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.
GO:1905110	negative regulation of pulmonary blood vessel remodeling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.
GO:1905111	positive regulation of pulmonary blood vessel remodeling	biological_process	Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.
GO:1905115	regulation of lateral attachment of mitotic spindle microtubules to kinetochore	biological_process	Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.
GO:1905116	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.
GO:1905117	regulation of ribonucleoside-diphosphate reductase activity	biological_process	Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.
GO:1905118	positive regulation of ribonucleoside-diphosphate reductase activity	biological_process	Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.
GO:1905119	response to haloperidol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
GO:1905120	cellular response to haloperidol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
GO:1905123	regulation of glucosylceramidase activity	biological_process	Any process that modulates the frequency, rate or extent of glucosylceramidase activity.
GO:1905124	negative regulation of glucosylceramidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.
GO:1905125	positive regulation of glucosylceramidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity.
GO:1905126	regulation of axo-dendritic protein transport	biological_process	Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.
GO:1905127	negative regulation of axo-dendritic protein transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.
GO:1905128	positive regulation of axo-dendritic protein transport	biological_process	Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.
GO:1905129	endocannabinoid signaling pathway involved in trans-synaptic signaling	biological_process	Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.
GO:1905130	carcinine import across plasma membrane	biological_process	The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1905131	carcinine transmembrane transporter activity	molecular_function	Enables the transfer of carcinine from one side of a membrane to the other.
GO:1905132	regulation of meiotic chromosome separation	biological_process	Any process that modulates the frequency, rate or extent of meiotic chromosome separation.
GO:1905133	negative regulation of meiotic chromosome separation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.
GO:1905134	positive regulation of meiotic chromosome separation	biological_process	Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation.
GO:1905135	biotin import across plasma membrane	biological_process	The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol.
GO:1905136	dethiobiotin import across plasma membrane	biological_process	The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol.
GO:1905137	regulation of viral DNA genome packaging via site-specific sequence recognition	biological_process	Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.
GO:1905138	positive regulation of viral DNA genome packaging via site-specific sequence recognition	biological_process	Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.
GO:1905139	apical ectodermal ridge formation	biological_process	The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.
GO:1905140	regulation of apical ectodermal ridge formation	biological_process	Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.
GO:1905141	negative regulation of apical ectodermal ridge formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.
GO:1905142	positive regulation of apical ectodermal ridge formation	biological_process	Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.
GO:1905143	eukaryotic translation initiation factor 2 complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.
GO:1905144	response to acetylcholine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
GO:1905145	cellular response to acetylcholine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
GO:1905146	lysosomal protein catabolic process	biological_process	Any cellular protein catabolic process that takes place in a lysosome.
GO:1905147	regulation of smooth muscle hypertrophy	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.
GO:1905148	negative regulation of smooth muscle hypertrophy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.
GO:1905149	positive regulation of smooth muscle hypertrophy	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.
GO:1905150	regulation of voltage-gated sodium channel activity	biological_process	Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity.
GO:1905151	negative regulation of voltage-gated sodium channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity.
GO:1905152	positive regulation of voltage-gated sodium channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity.
GO:1905153	regulation of membrane invagination	biological_process	Any process that modulates the frequency, rate or extent of membrane invagination.
GO:1905154	negative regulation of membrane invagination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.
GO:1905155	positive regulation of membrane invagination	biological_process	Any process that activates or increases the frequency, rate or extent of membrane invagination.
GO:1905156	negative regulation of photosynthesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.
GO:1905157	positive regulation of photosynthesis	biological_process	Any process that activates or increases the frequency, rate or extent of photosynthesis.
GO:1905161	protein localization to phagocytic vesicle	biological_process	A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.
GO:1905162	regulation of phagosome maturation	biological_process	Any process that modulates the frequency, rate or extent of phagosome maturation.
GO:1905163	negative regulation of phagosome maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.
GO:1905164	positive regulation of phagosome maturation	biological_process	Any process that activates or increases the frequency, rate or extent of phagosome maturation.
GO:1905165	regulation of lysosomal protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.
GO:1905166	negative regulation of lysosomal protein catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.
GO:1905167	positive regulation of lysosomal protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.
GO:1905168	positive regulation of double-strand break repair via homologous recombination	biological_process	Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.
GO:1905169	regulation of protein localization to phagocytic vesicle	biological_process	Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.
GO:1905170	negative regulation of protein localization to phagocytic vesicle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.
GO:1905171	positive regulation of protein localization to phagocytic vesicle	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.
GO:1905172	RISC complex binding	molecular_function	Binding to a RISC complex.
GO:1905173	eukaryotic translation initiation factor 2B complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex.
GO:1905174	regulation of vascular associated smooth muscle cell dedifferentiation	biological_process	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
GO:1905175	negative regulation of vascular associated smooth muscle cell dedifferentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
GO:1905176	positive regulation of vascular associated smooth muscle cell dedifferentiation	biological_process	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
GO:1905177	tracheary element differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element.
GO:1905178	regulation of cardiac muscle tissue regeneration	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.
GO:1905179	negative regulation of cardiac muscle tissue regeneration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.
GO:1905180	positive regulation of cardiac muscle tissue regeneration	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.
GO:1905181	regulation of urease activity	biological_process	Any process that modulates the frequency, rate or extent of urease activity.
GO:1905182	positive regulation of urease activity	biological_process	Any process that activates or increases the frequency, rate or extent of urease activity.
GO:1905183	negative regulation of protein serine/threonine phosphatase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.
GO:1905184	positive regulation of protein serine/threonine phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.
GO:1905186	regulation of metaphase/anaphase transition of meiosis I	biological_process	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
GO:1905187	negative regulation of metaphase/anaphase transition of meiosis I	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
GO:1905188	positive regulation of metaphase/anaphase transition of meiosis I	biological_process	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
GO:1905189	regulation of metaphase/anaphase transition of meiosis II	biological_process	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
GO:1905190	negative regulation of metaphase/anaphase transition of meiosis II	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
GO:1905191	positive regulation of metaphase/anaphase transition of meiosis II	biological_process	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
GO:1905192	regulation of chloroplast fission	biological_process	Any process that modulates the frequency, rate or extent of chloroplast fission.
GO:1905193	negative regulation of chloroplast fission	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission.
GO:1905194	positive regulation of chloroplast fission	biological_process	Any process that activates or increases the frequency, rate or extent of chloroplast fission.
GO:1905197	endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling	biological_process	Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid.
GO:1905198	manchette assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a manchette.
GO:1905199	manchette disassembly	biological_process	The disaggregation of a manchette into its constituent components.
GO:1905200	gibberellic acid transmembrane transport	biological_process	The directed movement of gibberellic acid across a membrane.
GO:1905201	gibberellin transmembrane transporter activity	molecular_function	Enables the transfer of gibberellin from one side of a membrane to the other.
GO:1905202	methylcrotonoyl-CoA carboxylase complex	cellular_component	A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity.
GO:1905203	regulation of connective tissue replacement	biological_process	Any process that modulates the frequency, rate or extent of connective tissue replacement.
GO:1905204	negative regulation of connective tissue replacement	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement.
GO:1905205	positive regulation of connective tissue replacement	biological_process	Any process that activates or increases the frequency, rate or extent of connective tissue replacement.
GO:1905207	regulation of cardiocyte differentiation	biological_process	Any process that modulates the frequency, rate or extent of cardiocyte differentiation.
GO:1905208	negative regulation of cardiocyte differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.
GO:1905209	positive regulation of cardiocyte differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.
GO:1905210	regulation of fibroblast chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.
GO:1905211	negative regulation of fibroblast chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.
GO:1905212	positive regulation of fibroblast chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.
GO:1905213	negative regulation of mitotic chromosome condensation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.
GO:1905214	regulation of RNA binding	biological_process	Any process that modulates the frequency, rate or extent of RNA binding.
GO:1905215	negative regulation of RNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.
GO:1905216	positive regulation of RNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of RNA binding.
GO:1905217	response to astaxanthin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.
GO:1905218	cellular response to astaxanthin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.
GO:1905219	regulation of platelet formation	biological_process	Any process that modulates the frequency, rate or extent of platelet formation.
GO:1905220	negative regulation of platelet formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.
GO:1905221	positive regulation of platelet formation	biological_process	Any process that activates or increases the frequency, rate or extent of platelet formation.
GO:1905222	atrioventricular canal morphogenesis	biological_process	The developmental process by which an atrioventricular canal is generated and organized.
GO:1905223	epicardium morphogenesis	biological_process	The developmental process by which an epicardium is generated and organized.
GO:1905225	response to thyrotropin-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
GO:1905229	cellular response to thyrotropin-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
GO:1905230	response to borneol	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.
GO:1905231	cellular response to borneol	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.
GO:1905232	cellular response to L-glutamate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.
GO:1905233	response to codeine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.
GO:1905234	cellular response to codeine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.
GO:1905235	response to quercetin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.
GO:1905236	cellular response to quercetin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.
GO:1905237	response to cyclosporin A	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.
GO:1905238	cellular response to cyclosporin A	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.
GO:1905239	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
GO:1905240	negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
GO:1905241	positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
GO:1905242	response to 3,3',5-triiodo-L-thyronine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.
GO:1905243	cellular response to 3,3',5-triiodo-L-thyronine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.
GO:1905244	regulation of modification of synaptic structure	biological_process	Any process that modulates the frequency, rate or extent of modification of synaptic structure.
GO:1905245	regulation of aspartic-type peptidase activity	biological_process	Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity.
GO:1905246	negative regulation of aspartic-type peptidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity.
GO:1905247	positive regulation of aspartic-type peptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity.
GO:1905251	epidermal growth factor receptor signaling pathway involved in heart process	biological_process	Any epidermal growth factor receptor signaling pathway that is involved in heart process.
GO:1905255	regulation of RNA binding transcription factor activity	biological_process	Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity.
GO:1905256	negative regulation of RNA binding transcription factor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.
GO:1905257	positive regulation of RNA binding transcription factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity.
GO:1905258	regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
GO:1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
GO:1905260	positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
GO:1905261	regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	biological_process	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
GO:1905262	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
GO:1905263	positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	biological_process	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
GO:1905264	blasticidin S metabolic process	biological_process	The chemical reactions and pathways involving blasticidin S.
GO:1905265	blasticidin S catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of blasticidin S.
GO:1905266	blasticidin S biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of blasticidin S.
GO:1905268	negative regulation of chromatin organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.
GO:1905269	positive regulation of chromatin organization	biological_process	Any process that activates or increases the frequency, rate or extent of chromatin organization.
GO:1905270	Meynert cell differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.
GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism	biological_process	Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
GO:1905272	negative regulation of proton-transporting ATP synthase activity, rotational mechanism	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
GO:1905273	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	biological_process	Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	biological_process	Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.
GO:1905275	Rohon-Beard neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.
GO:1905276	regulation of epithelial tube formation	biological_process	Any process that modulates the frequency, rate or extent of epithelial tube formation.
GO:1905277	negative regulation of epithelial tube formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.
GO:1905278	positive regulation of epithelial tube formation	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial tube formation.
GO:1905279	regulation of retrograde transport, endosome to Golgi	biological_process	Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.
GO:1905280	negative regulation of retrograde transport, endosome to Golgi	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.
GO:1905281	positive regulation of retrograde transport, endosome to Golgi	biological_process	Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.
GO:1905282	regulation of epidermal growth factor receptor signaling pathway involved in heart process	biological_process	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
GO:1905283	negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
GO:1905284	positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	biological_process	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
GO:1905285	fibrous ring of heart morphogenesis	biological_process	The developmental process by which a fibrous ring of heart is generated and organized.
GO:1905286	serine-type peptidase complex	cellular_component	A protein complex which is capable of serine-type peptidase activity.
GO:1905287	positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation	biological_process	Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.
GO:1905288	vascular associated smooth muscle cell apoptotic process	biological_process	Any apoptotic process in a vascular associated smooth muscle cell.
GO:1905289	regulation of CAMKK-AMPK signaling cascade	biological_process	Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade.
GO:1905290	negative regulation of CAMKK-AMPK signaling cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade.
GO:1905291	positive regulation of CAMKK-AMPK signaling cascade	biological_process	Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.
GO:1905292	regulation of neural crest cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of neural crest cell differentiation.
GO:1905293	negative regulation of neural crest cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.
GO:1905294	positive regulation of neural crest cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.
GO:1905295	regulation of neural crest cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of neural crest cell fate specification.
GO:1905296	negative regulation of neural crest cell fate specification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.
GO:1905297	positive regulation of neural crest cell fate specification	biological_process	Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification.
GO:1905298	regulation of intestinal epithelial cell development	biological_process	Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.
GO:1905299	negative regulation of intestinal epithelial cell development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.
GO:1905300	positive regulation of intestinal epithelial cell development	biological_process	Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.
GO:1905301	regulation of macropinocytosis	biological_process	Any process that modulates the frequency, rate or extent of macropinocytosis.
GO:1905302	negative regulation of macropinocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.
GO:1905303	positive regulation of macropinocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of macropinocytosis.
GO:1905304	regulation of cardiac myofibril assembly	biological_process	Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.
GO:1905305	negative regulation of cardiac myofibril assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.
GO:1905306	positive regulation of cardiac myofibril assembly	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.
GO:1905307	response to miconazole	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.
GO:1905308	cellular response to miconazole	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.
GO:1905309	positive regulation of cohesin loading	biological_process	Any process that activates or increases the frequency, rate or extent of cohesin loading.
GO:1905310	regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
GO:1905311	negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
GO:1905312	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
GO:1905314	semi-lunar valve development	biological_process	The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.
GO:1905315	cell proliferation involved in endocardial cushion morphogenesis	biological_process	Any cell proliferation that is involved in endocardial cushion morphogenesis.
GO:1905316	superior endocardial cushion morphogenesis	biological_process	The developmental process by which a superior endocardial cushion is generated and organized.
GO:1905317	inferior endocardial cushion morphogenesis	biological_process	The developmental process by which an inferior endocardial cushion is generated and organized.
GO:1905318	meiosis I spindle assembly checkpoint signaling	biological_process	Any spindle assembly checkpoint that is involved in meiosis I.
GO:1905319	mesenchymal stem cell migration	biological_process	The orderly movement of a mesenchymal stem cell from one site to another.
GO:1905320	regulation of mesenchymal stem cell migration	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.
GO:1905321	negative regulation of mesenchymal stem cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.
GO:1905322	positive regulation of mesenchymal stem cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.
GO:1905323	telomerase holoenzyme complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.
GO:1905324	telomere-telomerase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex.
GO:1905325	regulation of meiosis I spindle assembly checkpoint	biological_process	Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.
GO:1905326	positive regulation of meiosis I spindle assembly checkpoint	biological_process	Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.
GO:1905327	tracheoesophageal septum formation	biological_process	The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.
GO:1905328	plant septum development	biological_process	The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure.
GO:1905329	sphingoid long-chain base transport	biological_process	The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast.
GO:1905330	regulation of morphogenesis of an epithelium	biological_process	Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.
GO:1905331	negative regulation of morphogenesis of an epithelium	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.
GO:1905332	positive regulation of morphogenesis of an epithelium	biological_process	Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.
GO:1905333	regulation of gastric motility	biological_process	Any process that modulates the frequency, rate or extent of gastric motility.
GO:1905334	Swi5-Sfr1 complex binding	molecular_function	Binding to a Swi5-Sfr1 complex.
GO:1905335	regulation of aggrephagy	biological_process	Any process that modulates the frequency, rate or extent of aggrephagy.
GO:1905336	negative regulation of aggrephagy	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.
GO:1905337	positive regulation of aggrephagy	biological_process	Any process that activates or increases the frequency, rate or extent of aggrephagy.
GO:1905338	negative regulation of cohesin unloading	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.
GO:1905339	positive regulation of cohesin unloading	biological_process	Any process that activates or increases the frequency, rate or extent of cohesin unloading.
GO:1905340	regulation of protein localization to kinetochore	biological_process	Any process that modulates the frequency, rate or extent of protein localization to kinetochore.
GO:1905341	negative regulation of protein localization to kinetochore	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.
GO:1905342	positive regulation of protein localization to kinetochore	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.
GO:1905343	regulation of cohesin unloading	biological_process	Any process that modulates the frequency, rate or extent of cohesin unloading.
GO:1905344	prostaglandin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of prostaglandin.
GO:1905345	protein localization to cleavage furrow	biological_process	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow.
GO:1905346	protein localization to cleavage furrow rim	biological_process	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.
GO:1905347	endodeoxyribonuclease complex	cellular_component	A protein complex which is capable of endodeoxyribonuclease activity.
GO:1905348	endonuclease complex	cellular_component	A protein complex which is capable of endonuclease activity.
GO:1905349	ciliary transition zone assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.
GO:1905350	Y-shaped link assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate.
GO:1905351	pericyte cell migration	biological_process	The orderly movement of a pericyte cell from one site to another.
GO:1905352	ciliary necklace assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace.
GO:1905353	ciliary transition fiber assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber.
GO:1905354	exoribonuclease complex	cellular_component	A protein complex which is capable of exoribonuclease activity.
GO:1905355	spine apparatus assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.
GO:1905356	regulation of snRNA pseudouridine synthesis	biological_process	Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.
GO:1905357	negative regulation of snRNA pseudouridine synthesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.
GO:1905358	positive regulation of snRNA pseudouridine synthesis	biological_process	Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis.
GO:1905359	protein localization to meiotic spindle	biological_process	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.
GO:1905360	GTPase complex	cellular_component	A protein complex which is capable of GTPase activity.
GO:1905362	negative regulation of endosomal vesicle fusion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.
GO:1905363	positive regulation of endosomal vesicle fusion	biological_process	Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.
GO:1905364	regulation of endosomal vesicle fusion	biological_process	Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.
GO:1905365	regulation of intralumenal vesicle formation	biological_process	Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.
GO:1905366	negative regulation of intralumenal vesicle formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.
GO:1905367	positive regulation of intralumenal vesicle formation	biological_process	Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation.
GO:1905368	peptidase complex	cellular_component	A protein complex which is capable of peptidase activity.
GO:1905369	endopeptidase complex	cellular_component	A protein complex which is capable of endopeptidase activity.
GO:1905370	serine-type endopeptidase complex	cellular_component	A protein complex which is capable of serine-type endopeptidase activity.
GO:1905371	ceramide phosphoethanolamine metabolic process	biological_process	The chemical reactions and pathways involving ceramide phosphoethanolamine.
GO:1905372	ceramide phosphoethanolamine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.
GO:1905373	ceramide phosphoethanolamine biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.
GO:1905374	response to homocysteine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.
GO:1905375	cellular response to homocysteine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.
GO:1905376	negative regulation of cytochrome-c oxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.
GO:1905377	response to D-galactose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.
GO:1905378	cellular response to D-galactose	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.
GO:1905379	beta-N-acetylhexosaminidase complex	cellular_component	A protein complex which is capable of beta-N-acetylhexosaminidase activity.
GO:1905380	regulation of snRNA transcription by RNA polymerase II	biological_process	Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.
GO:1905381	negative regulation of snRNA transcription by RNA polymerase II	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.
GO:1905382	positive regulation of snRNA transcription by RNA polymerase II	biological_process	Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.
GO:1905383	protein localization to presynapse	biological_process	A process in which a protein is transported to, or maintained in, a location within a presynapse.
GO:1905384	regulation of protein localization to presynapse	biological_process	Any process that modulates the frequency, rate or extent of protein localization to presynapse.
GO:1905385	negative regulation of protein localization to presynapse	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.
GO:1905386	positive regulation of protein localization to presynapse	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.
GO:1905387	response to beta-carotene	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.
GO:1905388	cellular response to beta-carotene	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.
GO:1905389	response to leukotriene B4	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.
GO:1905390	cellular response to leukotriene B4	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.
GO:1905391	regulation of protein localization to cell division site involved in cell separation after cytokinesis	biological_process	Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis.
GO:1905392	plant organ morphogenesis	biological_process	The developmental process by which a plant organ is generated and organized.
GO:1905393	plant organ formation	biological_process	The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.
GO:1905394	retromer complex binding	molecular_function	Binding to a retromer complex.
GO:1905395	response to flavonoid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
GO:1905396	cellular response to flavonoid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
GO:1905397	activated CD8-positive, alpha-beta T cell apoptotic process	biological_process	Any apoptotic process in an activated CD8-positive, alpha-beta T cell.
GO:1905398	activated CD4-positive, alpha-beta T cell apoptotic process	biological_process	Any apoptotic process in an activated CD4-positive, alpha-beta T cell.
GO:1905399	regulation of activated CD4-positive, alpha-beta T cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
GO:1905400	negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
GO:1905401	positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
GO:1905402	regulation of activated CD8-positive, alpha-beta T cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
GO:1905403	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
GO:1905404	positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
GO:1905405	regulation of mitotic cohesin loading	biological_process	Any process that modulates the frequency, rate or extent of mitotic cohesin loading.
GO:1905406	positive regulation of mitotic cohesin loading	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.
GO:1905407	regulation of creatine transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity.
GO:1905408	negative regulation of creatine transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity.
GO:1905409	positive regulation of creatine transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity.
GO:1905410	regulation of mitotic cohesin unloading	biological_process	Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.
GO:1905411	positive regulation of mitotic cohesin unloading	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.
GO:1905412	negative regulation of mitotic cohesin loading	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.
GO:1905413	regulation of dense core granule exocytosis	biological_process	Any process that modulates the frequency, rate or extent of dense core granule exocytosis.
GO:1905414	negative regulation of dense core granule exocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.
GO:1905415	positive regulation of dense core granule exocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.
GO:1905416	regulation of amoeboid sperm motility	biological_process	Any process that modulates the frequency, rate or extent of amoeboid sperm motility.
GO:1905417	negative regulation of amoeboid sperm motility	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.
GO:1905418	positive regulation of amoeboid sperm motility	biological_process	Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.
GO:1905420	vascular associated smooth muscle cell differentiation involved in phenotypic switching	biological_process	Any vascular smooth muscle cell differentiation that is involved in phenotypic switching.
GO:1905421	regulation of plant organ morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of plant organ morphogenesis.
GO:1905422	negative regulation of plant organ morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.
GO:1905423	positive regulation of plant organ morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.
GO:1905424	regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
GO:1905425	negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
GO:1905426	positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
GO:1905427	intracellular signal transduction involved in positive regulation of cell growth	biological_process	Any intracellular signal transduction that is involved in positive regulation of cell growth.
GO:1905428	regulation of plant organ formation	biological_process	Any process that modulates the frequency, rate or extent of plant organ formation.
GO:1905429	response to glycine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.
GO:1905430	cellular response to glycine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.
GO:1905431	microcystin transport	biological_process	The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1905432	regulation of retrograde trans-synaptic signaling by neuropeptide	biological_process	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
GO:1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
GO:1905434	positive regulation of retrograde trans-synaptic signaling by neuropeptide	biological_process	Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
GO:1905438	non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	biological_process	Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
GO:1905439	response to chondroitin 6'-sulfate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.
GO:1905440	cellular response to chondroitin 6'-sulfate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.
GO:1905441	response to chondroitin 4'-sulfate	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.
GO:1905442	cellular response to chondroitin 4'-sulfate	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.
GO:1905443	regulation of clathrin coat assembly	biological_process	Any process that modulates the frequency, rate or extent of clathrin coat assembly.
GO:1905444	negative regulation of clathrin coat assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly.
GO:1905445	positive regulation of clathrin coat assembly	biological_process	Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.
GO:1905446	regulation of mitochondrial ATP synthesis coupled electron transport	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
GO:1905447	negative regulation of mitochondrial ATP synthesis coupled electron transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
GO:1905449	regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	biological_process	Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
GO:1905450	negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
GO:1905451	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
GO:1905453	regulation of myeloid progenitor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.
GO:1905454	negative regulation of myeloid progenitor cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.
GO:1905455	positive regulation of myeloid progenitor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.
GO:1905456	regulation of lymphoid progenitor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.
GO:1905457	negative regulation of lymphoid progenitor cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.
GO:1905458	positive regulation of lymphoid progenitor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
GO:1905462	regulation of DNA duplex unwinding	biological_process	Any process that modulates the frequency, rate or extent of DNA duplex unwinding.
GO:1905463	negative regulation of DNA duplex unwinding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding.
GO:1905464	positive regulation of DNA duplex unwinding	biological_process	Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding.
GO:1905465	regulation of G-quadruplex DNA unwinding	biological_process	Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding.
GO:1905466	negative regulation of G-quadruplex DNA unwinding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding.
GO:1905467	positive regulation of G-quadruplex DNA unwinding	biological_process	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding.
GO:1905474	canonical Wnt signaling pathway involved in stem cell proliferation	biological_process	Any canonical Wnt signaling pathway that is involved in stem cell proliferation.
GO:1905475	regulation of protein localization to membrane	biological_process	Any process that modulates the frequency, rate or extent of protein localization to membrane.
GO:1905476	negative regulation of protein localization to membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.
GO:1905477	positive regulation of protein localization to membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to membrane.
GO:1905483	regulation of motor neuron migration	biological_process	Any process that modulates the frequency, rate or extent of motor neuron migration.
GO:1905484	negative regulation of motor neuron migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.
GO:1905485	positive regulation of motor neuron migration	biological_process	Any process that activates or increases the frequency, rate or extent of motor neuron migration.
GO:1905486	regulation of anterior/posterior axon guidance	biological_process	Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.
GO:1905487	negative regulation of anterior/posterior axon guidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance.
GO:1905488	positive regulation of anterior/posterior axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.
GO:1905489	regulation of sensory neuron axon guidance	biological_process	Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.
GO:1905490	negative regulation of sensory neuron axon guidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.
GO:1905491	positive regulation of sensory neuron axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.
GO:1905492	positive regulation of branching morphogenesis of a nerve	biological_process	Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.
GO:1905493	regulation of G-quadruplex DNA binding	biological_process	Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding.
GO:1905494	negative regulation of G-quadruplex DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding.
GO:1905495	positive regulation of G-quadruplex DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding.
GO:1905496	regulation of triplex DNA binding	biological_process	Any process that modulates the frequency, rate or extent of triplex DNA binding.
GO:1905497	negative regulation of triplex DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding.
GO:1905498	positive regulation of triplex DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of triplex DNA binding.
GO:1905499	trichome papilla formation	biological_process	The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.
GO:1905502	acetyl-CoA binding	molecular_function	Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.
GO:1905503	regulation of motile cilium assembly	biological_process	Any process that modulates the frequency, rate or extent of motile cilium assembly.
GO:1905504	negative regulation of motile cilium assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.
GO:1905505	positive regulation of motile cilium assembly	biological_process	Any process that activates or increases the frequency, rate or extent of motile cilium assembly.
GO:1905506	gerontoplast stroma	cellular_component	Any plastid stroma that is part of a gerontoplast.
GO:1905508	protein localization to microtubule organizing center	biological_process	A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.
GO:1905509	protein localization to interphase microtubule organizing center	biological_process	A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.
GO:1905510	negative regulation of myosin II filament assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.
GO:1905511	positive regulation of myosin II filament assembly	biological_process	Any process that activates or increases the frequency, rate or extent of myosin II filament assembly.
GO:1905512	regulation of short-term synaptic potentiation	biological_process	Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.
GO:1905513	negative regulation of short-term synaptic potentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.
GO:1905514	positive regulation of short-term synaptic potentiation	biological_process	Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.
GO:1905515	non-motile cilium assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.
GO:1905516	positive regulation of fertilization	biological_process	Any process that activates or increases the frequency, rate or extent of fertilization.
GO:1905517	macrophage migration	biological_process	The orderly movement of a macrophage from one site to another.
GO:1905518	regulation of presynaptic active zone assembly	biological_process	Any process that modulates the frequency, rate or extent of presynaptic active zone assembly.
GO:1905519	negative regulation of presynaptic active zone assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.
GO:1905520	positive regulation of presynaptic active zone assembly	biological_process	Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.
GO:1905521	regulation of macrophage migration	biological_process	Any process that modulates the frequency, rate or extent of macrophage migration.
GO:1905522	negative regulation of macrophage migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.
GO:1905523	positive regulation of macrophage migration	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage migration.
GO:1905524	negative regulation of protein autoubiquitination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination.
GO:1905526	regulation of Golgi lumen acidification	biological_process	Any process that modulates the frequency, rate or extent of Golgi lumen acidification.
GO:1905527	negative regulation of Golgi lumen acidification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification.
GO:1905528	positive regulation of Golgi lumen acidification	biological_process	Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification.
GO:1905529	regulation of uracil import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of uracil import across plasma membrane.
GO:1905530	negative regulation of uracil import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.
GO:1905531	positive regulation of uracil import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.
GO:1905532	regulation of leucine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of leucine import across plasma membrane.
GO:1905533	negative regulation of leucine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane.
GO:1905534	positive regulation of leucine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane.
GO:1905535	regulation of eukaryotic translation initiation factor 4F complex assembly	biological_process	Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
GO:1905536	negative regulation of eukaryotic translation initiation factor 4F complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
GO:1905537	positive regulation of eukaryotic translation initiation factor 4F complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
GO:1905538	polysome binding	molecular_function	Binding to a polysome.
GO:1905539	regulation of postsynapse to nucleus signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway.
GO:1905540	interleukin-7 receptor complex	cellular_component	A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.
GO:1905541	regulation of L-arginine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.
GO:1905542	negative regulation of L-arginine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane.
GO:1905543	interleukin-15 receptor complex	cellular_component	A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors.
GO:1905544	L-methionine import across plasma membrane	biological_process	The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol.
GO:1905546	cellular response to phenylpropanoid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.
GO:1905550	regulation of protein localization to endoplasmic reticulum	biological_process	Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.
GO:1905551	negative regulation of protein localization to endoplasmic reticulum	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.
GO:1905552	positive regulation of protein localization to endoplasmic reticulum	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.
GO:1905553	regulation of blood vessel branching	biological_process	Any process that modulates the frequency, rate or extent of blood vessel branching.
GO:1905554	negative regulation of vessel branching	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.
GO:1905555	positive regulation of blood vessel branching	biological_process	Any process that activates or increases the frequency, rate or extent of blood vessel branching.
GO:1905556	ciliary vesicle assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.
GO:1905557	regulation of mitotic nuclear envelope disassembly	biological_process	Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.
GO:1905558	negative regulation of mitotic nuclear envelope disassembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.
GO:1905559	positive regulation of mitotic nuclear envelope disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.
GO:1905560	negative regulation of kinetochore assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly.
GO:1905561	positive regulation of kinetochore assembly	biological_process	Any process that activates or increases the frequency, rate or extent of kinetochore assembly.
GO:1905562	regulation of vascular endothelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.
GO:1905563	negative regulation of vascular endothelial cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.
GO:1905564	positive regulation of vascular endothelial cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
GO:1905568	regulation of ferrichrome biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process.
GO:1905569	negative regulation of ferrichrome biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process.
GO:1905570	positive regulation of ferrichrome biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process.
GO:1905571	interleukin-10 receptor complex	cellular_component	A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.
GO:1905572	ganglioside GM1 transport to membrane	biological_process	The directed movement of ganglioside GM1 to membrane.
GO:1905573	ganglioside GM1 binding	molecular_function	Binding to ganglioside GM1.
GO:1905574	ganglioside GM2 binding	molecular_function	Binding to ganglioside GM2.
GO:1905575	ganglioside GM3 binding	molecular_function	Binding to ganglioside GM3.
GO:1905576	ganglioside GT1b binding	molecular_function	Binding to ganglioside GT1b.
GO:1905577	ganglioside GP1c binding	molecular_function	Binding to ganglioside GP1c.
GO:1905578	regulation of ERBB3 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.
GO:1905579	negative regulation of ERBB3 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.
GO:1905580	positive regulation of ERBB3 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.
GO:1905581	positive regulation of low-density lipoprotein particle clearance	biological_process	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.
GO:1905582	response to mannose	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.
GO:1905583	cellular response to mannose	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.
GO:1905584	outer hair cell apoptotic process	biological_process	Any apoptotic process in an outer hair cell.
GO:1905585	regulation of outer hair cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process.
GO:1905586	negative regulation of outer hair cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.
GO:1905587	positive regulation of outer hair cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.
GO:1905588	plant-type cell wall modification involved in stomatal movement	biological_process	Any plant-type cell wall modification that is involved in stomatal movement.
GO:1905589	positive regulation of L-arginine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.
GO:1905590	fibronectin fibril organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.
GO:1905591	regulation of optical nerve axon regeneration	biological_process	Any process that modulates the frequency, rate or extent of optical nerve axon regeneration.
GO:1905592	negative regulation of optical nerve axon regeneration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration.
GO:1905593	positive regulation of optical nerve axon regeneration	biological_process	Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration.
GO:1905594	resveratrol binding	molecular_function	Binding to resveratrol.
GO:1905595	regulation of low-density lipoprotein particle receptor binding	biological_process	Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding.
GO:1905596	negative regulation of low-density lipoprotein particle receptor binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding.
GO:1905597	positive regulation of low-density lipoprotein particle receptor binding	biological_process	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding.
GO:1905598	negative regulation of low-density lipoprotein receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.
GO:1905599	positive regulation of low-density lipoprotein receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity.
GO:1905600	regulation of receptor-mediated endocytosis involved in cholesterol transport	biological_process	Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
GO:1905601	negative regulation of receptor-mediated endocytosis involved in cholesterol transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	biological_process	Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
GO:1905603	regulation of blood-brain barrier permeability	biological_process	Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
GO:1905604	negative regulation of blood-brain barrier permeability	biological_process	Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
GO:1905605	positive regulation of blood-brain barrier permeability	biological_process	Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
GO:1905606	regulation of presynapse assembly	biological_process	Any process that modulates the frequency, rate or extent of presynapse assembly.
GO:1905607	negative regulation of presynapse assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.
GO:1905608	positive regulation of presynapse assembly	biological_process	Any process that activates or increases the frequency, rate or extent of presynapse assembly.
GO:1905609	positive regulation of smooth muscle cell-matrix adhesion	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.
GO:1905610	regulation of mRNA cap binding	biological_process	Any process that modulates the frequency, rate or extent of mRNA cap binding.
GO:1905611	negative regulation of mRNA cap binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.
GO:1905612	positive regulation of mRNA cap binding	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA cap binding.
GO:1905613	regulation of developmental vegetative growth	biological_process	Any process that modulates the frequency, rate or extent of developmental vegetative growth.
GO:1905614	negative regulation of developmental vegetative growth	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.
GO:1905615	positive regulation of developmental vegetative growth	biological_process	Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.
GO:1905619	regulation of alpha-(1->3)-fucosyltransferase activity	biological_process	Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
GO:1905620	negative regulation of alpha-(1->3)-fucosyltransferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
GO:1905621	positive regulation of alpha-(1->3)-fucosyltransferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
GO:1905622	negative regulation of leaf development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.
GO:1905623	positive regulation of leaf development	biological_process	Any process that activates or increases the frequency, rate or extent of leaf development.
GO:1905624	regulation of L-methionine import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane.
GO:1905625	negative regulation of L-methionine import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane.
GO:1905626	positive regulation of L-methionine import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.
GO:1905627	regulation of serotonin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.
GO:1905628	negative regulation of serotonin biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.
GO:1905629	positive regulation of serotonin biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.
GO:1905630	response to glyceraldehyde	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.
GO:1905631	cellular response to glyceraldehyde	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.
GO:1905632	protein localization to euchromatin	biological_process	A process in which a protein is transported to, or maintained in, a location within an euchromatin.
GO:1905633	establishment of protein localization to euchromatin	biological_process	The directed movement of a protein to a specific location in an euchromatin.
GO:1905634	regulation of protein localization to chromatin	biological_process	Any process that modulates the frequency, rate or extent of protein localization to chromatin.
GO:1905635	FACT complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a FACT complex.
GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
GO:1905637	regulation of mitochondrial mRNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.
GO:1905638	negative regulation of mitochondrial mRNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.
GO:1905639	positive regulation of mitochondrial mRNA catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.
GO:1905640	response to acetaldehyde	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.
GO:1905641	cellular response to acetaldehyde	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.
GO:1905642	negative regulation of DNA methylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.
GO:1905643	positive regulation of DNA methylation	biological_process	Any process that activates or increases the frequency, rate or extent of DNA methylation.
GO:1905644	regulation of FACT complex assembly	biological_process	Any process that modulates the frequency, rate or extent of FACT complex assembly.
GO:1905645	negative regulation of FACT complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly.
GO:1905646	positive regulation of FACT complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of FACT complex assembly.
GO:1905647	proline import across plasma membrane	biological_process	The directed movement of proline from outside of a cell into the cytoplasmic compartment.
GO:1905648	regulation of shell calcification	biological_process	Any process that modulates the frequency, rate or extent of shell calcification.
GO:1905649	negative regulation of shell calcification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.
GO:1905650	positive regulation of shell calcification	biological_process	Any process that activates or increases the frequency, rate or extent of shell calcification.
GO:1905651	regulation of artery morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of artery morphogenesis.
GO:1905652	negative regulation of artery morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.
GO:1905653	positive regulation of artery morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of artery morphogenesis.
GO:1905654	regulation of artery smooth muscle contraction	biological_process	Any process that modulates the frequency, rate or extent of artery smooth muscle contraction.
GO:1905655	negative regulation of artery smooth muscle contraction	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.
GO:1905656	positive regulation of artery smooth muscle contraction	biological_process	Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction.
GO:1905660	mitotic checkpoint complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.
GO:1905661	regulation of telomerase RNA reverse transcriptase activity	biological_process	Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
GO:1905662	negative regulation of telomerase RNA reverse transcriptase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
GO:1905663	positive regulation of telomerase RNA reverse transcriptase activity	biological_process	Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
GO:1905664	regulation of calcium ion import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.
GO:1905665	positive regulation of calcium ion import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.
GO:1905666	regulation of protein localization to endosome	biological_process	Any process that modulates the frequency, rate or extent of protein localization to endosome.
GO:1905667	negative regulation of protein localization to endosome	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
GO:1905668	positive regulation of protein localization to endosome	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to endosome.
GO:1905669	TORC1 complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.
GO:1905670	TORC2 complex disassembly	biological_process	The disaggregation of a TORC2 complex into its constituent components.
GO:1905671	regulation of lysosome organization	biological_process	Any process that modulates the frequency, rate or extent of lysosome organization.
GO:1905672	negative regulation of lysosome organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.
GO:1905673	positive regulation of lysosome organization	biological_process	Any process that activates or increases the frequency, rate or extent of lysosome organization.
GO:1905674	regulation of adaptive immune memory response	biological_process	Any process that modulates the frequency, rate or extent of adaptive immune memory response.
GO:1905675	negative regulation of adaptive immune memory response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.
GO:1905676	positive regulation of adaptive immune memory response	biological_process	Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.
GO:1905677	regulation of adaptive immune effector response	biological_process	Any process that modulates the frequency, rate or extent of adaptive immune effector response.
GO:1905678	negative regulation of adaptive immune effector response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.
GO:1905679	positive regulation of adaptive immune effector response	biological_process	Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.
GO:1905680	regulation of innate immunity memory response	biological_process	Any process that modulates the frequency, rate or extent of innate immunity memory response.
GO:1905681	negative regulation of innate immunity memory response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.
GO:1905682	positive regulation of innate immunity memory response	biological_process	Any process that activates or increases the frequency, rate or extent of innate immunity memory response.
GO:1905683	peroxisome disassembly	biological_process	The disaggregation of a peroxisome into its constituent components.
GO:1905684	regulation of plasma membrane repair	biological_process	Any process that modulates the frequency, rate or extent of plasma membrane repair.
GO:1905685	negative regulation of plasma membrane repair	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.
GO:1905686	positive regulation of plasma membrane repair	biological_process	Any process that activates or increases the frequency, rate or extent of plasma membrane repair.
GO:1905687	regulation of diacylglycerol kinase activity	biological_process	Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.
GO:1905688	negative regulation of diacylglycerol kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity.
GO:1905689	positive regulation of diacylglycerol kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.
GO:1905690	nucleus disassembly	biological_process	The disaggregation of a nucleus into its constituent components.
GO:1905691	lipid droplet disassembly	biological_process	The disaggregation of a lipid particle into its constituent components.
GO:1905692	endoplasmic reticulum disassembly	biological_process	The disaggregation of an endoplasmic reticulum into its constituent components.
GO:1905693	regulation of phosphatidic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.
GO:1905694	negative regulation of phosphatidic acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.
GO:1905695	positive regulation of phosphatidic acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.
GO:1905696	regulation of polysome binding	biological_process	Any process that modulates the frequency, rate or extent of polysome binding.
GO:1905697	negative regulation of polysome binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding.
GO:1905698	positive regulation of polysome binding	biological_process	Any process that activates or increases the frequency, rate or extent of polysome binding.
GO:1905699	regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:1905700	negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:1905701	positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
GO:1905702	regulation of inhibitory synapse assembly	biological_process	Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.
GO:1905703	negative regulation of inhibitory synapse assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.
GO:1905704	positive regulation of inhibitory synapse assembly	biological_process	Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly.
GO:1905706	regulation of mitochondrial ATP synthesis coupled proton transport	biological_process	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.
GO:1905707	negative regulation of mitochondrial ATP synthesis coupled proton transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.
GO:1905708	regulation of cell morphogenesis involved in conjugation with cellular fusion	biological_process	Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.
GO:1905709	negative regulation of membrane permeability	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.
GO:1905710	positive regulation of membrane permeability	biological_process	Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.
GO:1905711	response to phosphatidylethanolamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
GO:1905712	cellular response to phosphatidylethanolamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
GO:1905715	regulation of cornification	biological_process	Any process that modulates the frequency, rate or extent of cornification.
GO:1905716	negative regulation of cornification	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cornification.
GO:1905717	positive regulation of cornification	biological_process	Any process that activates or increases the frequency, rate or extent of cornification.
GO:1905719	protein localization to perinuclear region of cytoplasm	biological_process	A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.
GO:1905720	cytoplasmic microtubule bundle	cellular_component	Any microtubule bundle that is part of a cytoplasm.
GO:1905721	mitotic spindle astral microtubule end	cellular_component	Any microtubule end that is part of a mitotic spindle astral microtubule.
GO:1905722	regulation of trypanothione biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process.
GO:1905723	negative regulation of trypanothione biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process.
GO:1905724	positive regulation of trypanothione biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process.
GO:1905725	protein localization to microtubule end	biological_process	A process in which a protein is transported to, or maintained in, a location at a microtubule end.
GO:1905735	regulation of L-proline import across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane.
GO:1905736	negative regulation of L-proline import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane.
GO:1905737	positive regulation of L-proline import across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.
GO:1905741	calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration	biological_process	Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration.
GO:1905742	Ras guanyl-nucleotide exchange factor complex	cellular_component	A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity.
GO:1905743	calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration	biological_process	Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration.
GO:1905744	regulation of mRNA cis splicing, via spliceosome	biological_process	Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.
GO:1905745	negative regulation of mRNA cis splicing, via spliceosome	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.
GO:1905746	positive regulation of mRNA cis splicing, via spliceosome	biological_process	Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.
GO:1905747	negative regulation of saliva secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.
GO:1905748	hard palate morphogenesis	biological_process	The developmental process by which a hard palate is generated and organized.
GO:1905749	regulation of endosome to plasma membrane protein transport	biological_process	Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.
GO:1905750	negative regulation of endosome to plasma membrane protein transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.
GO:1905751	positive regulation of endosome to plasma membrane protein transport	biological_process	Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.
GO:1905754	ascospore-type prospore nucleus	cellular_component	Any nucleus that is part of a ascospore-type prospore.
GO:1905755	protein localization to cytoplasmic microtubule	biological_process	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.
GO:1905756	regulation of primary cell septum biogenesis	biological_process	Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.
GO:1905757	negative regulation of primary cell septum biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.
GO:1905758	positive regulation of primary cell septum biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.
GO:1905759	post-anaphase array microtubule	cellular_component	Any microtubule that is part of a post-anaphase microtubule array.
GO:1905760	post-anaphase array microtubule end	cellular_component	Any microtubule end that is part of a post-anaphase array microtubule.
GO:1905761	SCF ubiquitin ligase complex binding	molecular_function	Binding to a SCF ubiquitin ligase complex.
GO:1905762	CCR4-NOT complex binding	molecular_function	Binding to a CCR4-NOT complex.
GO:1905763	MTREC complex binding	molecular_function	Binding to a MTREC complex.
GO:1905764	regulation of protection from non-homologous end joining at telomere	biological_process	Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.
GO:1905765	negative regulation of protection from non-homologous end joining at telomere	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.
GO:1905766	positive regulation of protection from non-homologous end joining at telomere	biological_process	Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.
GO:1905767	regulation of double-stranded telomeric DNA binding	biological_process	Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.
GO:1905768	negative regulation of double-stranded telomeric DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding.
GO:1905769	positive regulation of double-stranded telomeric DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding.
GO:1905770	regulation of mesodermal cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.
GO:1905771	negative regulation of mesodermal cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.
GO:1905772	positive regulation of mesodermal cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.
GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding	molecular_function	Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.
GO:1905774	regulation of DNA helicase activity	biological_process	Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.
GO:1905775	negative regulation of DNA helicase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity.
GO:1905776	positive regulation of DNA helicase activity	biological_process	Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity.
GO:1905777	regulation of exonuclease activity	biological_process	Any process that modulates the frequency, rate or extent of exonuclease activity.
GO:1905778	negative regulation of exonuclease activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.
GO:1905779	positive regulation of exonuclease activity	biological_process	Any process that activates or increases the frequency, rate or extent of exonuclease activity.
GO:1905780	regulation of phosphatidylserine exposure on apoptotic cell surface	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
GO:1905781	negative regulation of phosphatidylserine exposure on apoptotic cell surface	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
GO:1905782	positive regulation of phosphatidylserine exposure on apoptotic cell surface	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
GO:1905784	regulation of anaphase-promoting complex-dependent catabolic process	biological_process	Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
GO:1905785	negative regulation of anaphase-promoting complex-dependent catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
GO:1905786	positive regulation of anaphase-promoting complex-dependent catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
GO:1905787	regulation of detection of mechanical stimulus involved in sensory perception of touch	biological_process	Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
GO:1905788	negative regulation of detection of mechanical stimulus involved in sensory perception of touch	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
GO:1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch	biological_process	Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
GO:1905790	regulation of mechanosensory behavior	biological_process	Any process that modulates the frequency, rate or extent of mechanosensory behavior.
GO:1905791	negative regulation of mechanosensory behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior.
GO:1905792	positive regulation of mechanosensory behavior	biological_process	Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.
GO:1905793	protein localization to pericentriolar material	biological_process	A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.
GO:1905794	response to puromycin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.
GO:1905795	cellular response to puromycin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.
GO:1905796	regulation of intraciliary anterograde transport	biological_process	Any process that modulates the frequency, rate or extent of intraciliary anterograde transport.
GO:1905797	negative regulation of intraciliary anterograde transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.
GO:1905798	positive regulation of intraciliary anterograde transport	biological_process	Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.
GO:1905799	regulation of intraciliary retrograde transport	biological_process	Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.
GO:1905800	negative regulation of intraciliary retrograde transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.
GO:1905801	positive regulation of intraciliary retrograde transport	biological_process	Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.
GO:1905802	regulation of cellular response to manganese ion	biological_process	Any process that modulates the frequency, rate or extent of cellular response to manganese ion.
GO:1905803	negative regulation of cellular response to manganese ion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.
GO:1905804	positive regulation of cellular response to manganese ion	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.
GO:1905805	excitatory synapse pruning	biological_process	The disaggregation of an excitatory synapse into its constituent components.
GO:1905806	regulation of synapse pruning	biological_process	Any process that modulates the frequency, rate or extent of synapse pruning.
GO:1905807	negative regulation of synapse pruning	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning.
GO:1905808	positive regulation of synapse pruning	biological_process	Any process that activates or increases the frequency, rate or extent of synapse pruning.
GO:1905809	negative regulation of synapse organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.
GO:1905810	regulation of excitatory synapse pruning	biological_process	Any process that modulates the frequency, rate or extent of excitatory synapse pruning.
GO:1905811	negative regulation of excitatory synapse pruning	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.
GO:1905812	regulation of motor neuron axon guidance	biological_process	Any process that modulates the frequency, rate or extent of motor neuron axon guidance.
GO:1905813	negative regulation of motor neuron axon guidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance.
GO:1905814	positive regulation of motor neuron axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.
GO:1905815	regulation of dorsal/ventral axon guidance	biological_process	Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance.
GO:1905816	negative regulation of dorsal/ventral axon guidance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance.
GO:1905817	positive regulation of dorsal/ventral axon guidance	biological_process	Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance.
GO:1905818	regulation of chromosome separation	biological_process	Any process that modulates the frequency, rate or extent of chromosome separation.
GO:1905819	negative regulation of chromosome separation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.
GO:1905820	positive regulation of chromosome separation	biological_process	Any process that activates or increases the frequency, rate or extent of chromosome separation.
GO:1905821	positive regulation of chromosome condensation	biological_process	Any process that activates or increases the frequency, rate or extent of chromosome condensation.
GO:1905822	regulation of mitotic sister chromatid arm separation	biological_process	Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation.
GO:1905823	negative regulation of mitotic sister chromatid arm separation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation.
GO:1905824	positive regulation of mitotic sister chromatid arm separation	biological_process	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation.
GO:1905825	regulation of selenocysteine metabolic process	biological_process	Any process that modulates the frequency, rate or extent of selenocysteine metabolic process.
GO:1905826	negative regulation of selenocysteine metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process.
GO:1905827	positive regulation of selenocysteine metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process.
GO:1905828	regulation of prostaglandin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.
GO:1905829	negative regulation of prostaglandin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.
GO:1905830	positive regulation of prostaglandin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process.
GO:1905831	negative regulation of spindle assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.
GO:1905832	positive regulation of spindle assembly	biological_process	Any process that activates or increases the frequency, rate or extent of spindle assembly.
GO:1905833	negative regulation of microtubule nucleation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.
GO:1905834	response to pyrimidine ribonucleotide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.
GO:1905835	cellular response to pyrimidine ribonucleotide	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.
GO:1905836	response to triterpenoid	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.
GO:1905837	cellular response to triterpenoid	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.
GO:1905838	regulation of telomeric D-loop disassembly	biological_process	Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.
GO:1905839	negative regulation of telomeric D-loop disassembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.
GO:1905840	positive regulation of telomeric D-loop disassembly	biological_process	Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.
GO:1905841	response to oxidopamine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.
GO:1905842	cellular response to oxidopamine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.
GO:1905843	regulation of cellular response to gamma radiation	biological_process	Any process that modulates the frequency, rate or extent of cellular response to gamma radiation.
GO:1905844	negative regulation of cellular response to gamma radiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation.
GO:1905845	positive regulation of cellular response to gamma radiation	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.
GO:1905846	regulation of cellular response to oxidopamine	biological_process	Any process that modulates the frequency, rate or extent of cellular response to oxidopamine.
GO:1905847	negative regulation of cellular response to oxidopamine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine.
GO:1905848	positive regulation of cellular response to oxidopamine	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine.
GO:1905849	negative regulation of forward locomotion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion.
GO:1905850	positive regulation of forward locomotion	biological_process	Any process that activates or increases the frequency, rate or extent of forward locomotion.
GO:1905851	negative regulation of backward locomotion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion.
GO:1905852	positive regulation of backward locomotion	biological_process	Any process that activates or increases the frequency, rate or extent of backward locomotion.
GO:1905853	regulation of heparan sulfate binding	biological_process	Any process that modulates the frequency, rate or extent of heparan sulfate binding.
GO:1905854	negative regulation of heparan sulfate binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding.
GO:1905855	positive regulation of heparan sulfate binding	biological_process	Any process that activates or increases the frequency, rate or extent of heparan sulfate binding.
GO:1905856	negative regulation of pentose-phosphate shunt	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt.
GO:1905857	positive regulation of pentose-phosphate shunt	biological_process	Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt.
GO:1905858	regulation of heparan sulfate proteoglycan binding	biological_process	Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding.
GO:1905859	negative regulation of heparan sulfate proteoglycan binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding.
GO:1905860	positive regulation of heparan sulfate proteoglycan binding	biological_process	Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding.
GO:1905861	intranuclear rod assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.
GO:1905862	ferroxidase complex	cellular_component	A protein complex which is capable of ferroxidase activity.
GO:1905864	regulation of Atg1/ULK1 kinase complex assembly	biological_process	Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.
GO:1905865	negative regulation of Atg1/ULK1 kinase complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.
GO:1905866	positive regulation of Atg1/ULK1 kinase complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.
GO:1905867	epididymis development	biological_process	The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.
GO:1905868	regulation of 3'-UTR-mediated mRNA stabilization	biological_process	Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.
GO:1905869	negative regulation of 3'-UTR-mediated mRNA stabilization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.
GO:1905870	positive regulation of 3'-UTR-mediated mRNA stabilization	biological_process	Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.
GO:1905871	regulation of protein localization to cell leading edge	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.
GO:1905872	negative regulation of protein localization to cell leading edge	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.
GO:1905873	positive regulation of protein localization to cell leading edge	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.
GO:1905874	regulation of postsynaptic density organization	biological_process	Any process that modulates the frequency, rate or extent of postsynaptic density organization.
GO:1905875	negative regulation of postsynaptic density organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.
GO:1905876	positive regulation of postsynaptic density organization	biological_process	Any process that activates or increases the frequency, rate or extent of postsynaptic density organization.
GO:1905879	regulation of oogenesis	biological_process	Any process that modulates the frequency, rate or extent of oogenesis.
GO:1905880	negative regulation of oogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.
GO:1905881	positive regulation of oogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of oogenesis.
GO:1905883	regulation of triglyceride transport	biological_process	Any process that modulates the frequency, rate or extent of triglyceride transport.
GO:1905884	negative regulation of triglyceride transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport.
GO:1905885	positive regulation of triglyceride transport	biological_process	Any process that activates or increases the frequency, rate or extent of triglyceride transport.
GO:1905887	autoinducer AI-2 transmembrane transport	biological_process	The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing.
GO:1905888	negative regulation of cellular response to very-low-density lipoprotein particle stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.
GO:1905889	positive regulation of cellular response to very-low-density lipoprotein particle stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.
GO:1905890	regulation of cellular response to very-low-density lipoprotein particle stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.
GO:1905897	regulation of response to endoplasmic reticulum stress	biological_process	Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.
GO:1905898	positive regulation of response to endoplasmic reticulum stress	biological_process	Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.
GO:1905899	regulation of smooth muscle tissue development	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle tissue development.
GO:1905900	negative regulation of smooth muscle tissue development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development.
GO:1905901	positive regulation of smooth muscle tissue development	biological_process	Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.
GO:1905902	regulation of mesoderm formation	biological_process	Any process that modulates the frequency, rate or extent of mesoderm formation.
GO:1905903	negative regulation of mesoderm formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.
GO:1905904	positive regulation of mesoderm formation	biological_process	Any process that activates or increases the frequency, rate or extent of mesoderm formation.
GO:1905905	pharyngeal gland morphogenesis	biological_process	The developmental process by which a pharyngeal gland is generated and organized.
GO:1905906	regulation of amyloid fibril formation	biological_process	Any process that modulates the frequency, rate or extent of amyloid fibril formation.
GO:1905907	negative regulation of amyloid fibril formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation.
GO:1905908	positive regulation of amyloid fibril formation	biological_process	Any process that activates or increases the frequency, rate or extent of amyloid fibril formation.
GO:1905909	regulation of dauer entry	biological_process	Any process that modulates the frequency, rate or extent of dauer entry.
GO:1905910	negative regulation of dauer entry	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry.
GO:1905911	positive regulation of dauer entry	biological_process	Any process that activates or increases the frequency, rate or extent of dauer entry.
GO:1905912	regulation of calcium ion export across plasma membrane	biological_process	Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.
GO:1905913	negative regulation of calcium ion export across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.
GO:1905914	positive regulation of calcium ion export across plasma membrane	biological_process	Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.
GO:1905915	regulation of cell differentiation involved in phenotypic switching	biological_process	Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching.
GO:1905916	negative regulation of cell differentiation involved in phenotypic switching	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.
GO:1905917	positive regulation of cell differentiation involved in phenotypic switching	biological_process	Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching.
GO:1905918	regulation of CoA-transferase activity	biological_process	Any process that modulates the frequency, rate or extent of CoA-transferase activity.
GO:1905919	negative regulation of CoA-transferase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity.
GO:1905920	positive regulation of CoA-transferase activity	biological_process	Any process that activates or increases the frequency, rate or extent of CoA-transferase activity.
GO:1905921	regulation of acetylcholine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.
GO:1905922	negative regulation of acetylcholine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.
GO:1905923	positive regulation of acetylcholine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.
GO:1905930	regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	biological_process	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
GO:1905931	negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
GO:1905932	positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	biological_process	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
GO:1905933	regulation of cell fate determination	biological_process	Any process that modulates the frequency, rate or extent of cell fate determination.
GO:1905934	negative regulation of cell fate determination	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.
GO:1905935	positive regulation of cell fate determination	biological_process	Any process that activates or increases the frequency, rate or extent of cell fate determination.
GO:1905936	regulation of germ cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of germ cell proliferation.
GO:1905937	negative regulation of germ cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.
GO:1905938	positive regulation of germ cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of germ cell proliferation.
GO:1905939	regulation of gonad development	biological_process	Any process that modulates the frequency, rate or extent of gonad development.
GO:1905940	negative regulation of gonad development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.
GO:1905941	positive regulation of gonad development	biological_process	Any process that activates or increases the frequency, rate or extent of gonad development.
GO:1905942	regulation of formation of growth cone in injured axon	biological_process	Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.
GO:1905943	negative regulation of formation of growth cone in injured axon	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon.
GO:1905944	positive regulation of formation of growth cone in injured axon	biological_process	Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon.
GO:1905945	regulation of response to calcium ion	biological_process	Any process that modulates the frequency, rate or extent of response to calcium ion.
GO:1905946	negative regulation of response to calcium ion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.
GO:1905947	positive regulation of response to calcium ion	biological_process	Any process that activates or increases the frequency, rate or extent of response to calcium ion.
GO:1905948	ABC-type 3',5'-cyclic GMP transmembrane transporter activity	molecular_function	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out).
GO:1905949	negative regulation of calcium ion import across plasma membrane	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.
GO:1905951	mitochondrion DNA recombination	biological_process	Any DNA recombination that takes place in mitochondrion.
GO:1905952	regulation of lipid localization	biological_process	Any process that modulates the frequency, rate or extent of lipid localization.
GO:1905953	negative regulation of lipid localization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.
GO:1905954	positive regulation of lipid localization	biological_process	Any process that activates or increases the frequency, rate or extent of lipid localization.
GO:1905955	negative regulation of endothelial tube morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.
GO:1905956	positive regulation of endothelial tube morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.
GO:1905957	regulation of cellular response to alcohol	biological_process	Any process that modulates the frequency, rate or extent of cellular response to alcohol.
GO:1905958	negative regulation of cellular response to alcohol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.
GO:1905959	positive regulation of cellular response to alcohol	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.
GO:1905960	response to differentiation-inducing factor 2	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.
GO:1905961	protein-cysteine S-palmitoyltransferase complex	cellular_component	A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity.
GO:1905962	glutamatergic neuron differentiation	biological_process	The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.
GO:1990000	amyloid fibril formation	biological_process	The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins.
GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	biological_process	Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.
GO:1990002	methylglyoxal reductase (NADPH-dependent, acetol producing)	molecular_function	Catalysis of the reaction: hydroxyacetone + NADP+ = H+ + methylglyoxal + NADPH.
GO:1990003	IDP phosphatase activity	molecular_function	Catalysis of the reaction: IDP + H2O = IMP + H+ + phosphate.
GO:1990005	granular vesicle	cellular_component	A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
GO:1990006	amorphous vesicle	cellular_component	A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.
GO:1990007	membrane stack	cellular_component	A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.
GO:1990008	neurosecretory vesicle	cellular_component	A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.
GO:1990009	retinal cell apoptotic process	biological_process	Any apoptotic process in a retinal cell.
GO:1990010	compound eye retinal cell apoptotic process	biological_process	Any apoptotic process in a compound eye retinal cell.
GO:1990011	laminated body	cellular_component	Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.
GO:1990012	complex laminated body	cellular_component	A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.
GO:1990013	presynaptic grid	cellular_component	A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.
GO:1990014	orthogonal array	cellular_component	Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).
GO:1990015	ensheathing process	cellular_component	A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.
GO:1990016	neck portion of tanycyte	cellular_component	Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
GO:1990017	somatic portion of tanycyte	cellular_component	Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
GO:1990018	tail portion of tanycyte	cellular_component	Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.
GO:1990019	protein storage vacuole organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.
GO:1990020	recurrent axon collateral	cellular_component	Axon collateral that ramifies in the area of the soma of the cell of origin.
GO:1990021	Schaffer axon collateral	cellular_component	Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.
GO:1990023	mitotic spindle midzone	cellular_component	The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
GO:1990024	C bouton	cellular_component	Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.
GO:1990025	F bouton	cellular_component	Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.
GO:1990026	hippocampal mossy fiber expansion	cellular_component	Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.
GO:1990027	S bouton	cellular_component	Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.
GO:1990028	intermediate voltage-gated calcium channel activity	molecular_function	Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.
GO:1990029	vasomotion	biological_process	The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.
GO:1990030	pericellular basket	cellular_component	Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.
GO:1990031	pinceau fiber	cellular_component	Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.
GO:1990032	parallel fiber	cellular_component	A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.
GO:1990033	dendritic branch point	cellular_component	The part of a dendritic tree where it branches, giving rise to a dendritic branch.
GO:1990034	calcium ion export across plasma membrane	biological_process	The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.
GO:1990036	calcium ion import into sarcoplasmic reticulum	biological_process	The directed movement of calcium ions into a sarcoplasmic reticulum.
GO:1990037	Lewy body core	cellular_component	The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.
GO:1990038	Lewy body corona	cellular_component	The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.
GO:1990039	hypolemmal cisterna	cellular_component	Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.
GO:1990040	sub-surface cisterna	cellular_component	Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.
GO:1990042	glycerol dehydrogenase [NAD(P)+] activity	molecular_function	Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.
GO:1990043	5' deoxyribonuclease (pyrimidine dimer) activity	molecular_function	Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.
GO:1990044	protein localization to lipid droplet	biological_process	A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.
GO:1990045	sclerotium development	biological_process	The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.
GO:1990046	stress-induced mitochondrial fusion	biological_process	Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
GO:1990047	spindle matrix	cellular_component	A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.
GO:1990048	anterograde neuronal dense core vesicle transport	biological_process	The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.
GO:1990049	retrograde neuronal dense core vesicle transport	biological_process	The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.
GO:1990050	phosphatidic acid transfer activity	molecular_function	Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.
GO:1990051	activation of protein kinase C activity	biological_process	Any process that initiates the activity of the inactive enzyme protein kinase C.
GO:1990052	ER to chloroplast lipid transport	biological_process	The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.
GO:1990053	DNA-5-methylcytosine glycosylase activity	molecular_function	Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.
GO:1990054	response to temozolomide	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
GO:1990055	phenylacetaldehyde synthase activity	molecular_function	Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2.
GO:1990058	fruit replum development	biological_process	The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.
GO:1990059	fruit valve development	biological_process	The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.
GO:1990060	maltose transport complex	cellular_component	Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.
GO:1990061	bacterial degradosome	cellular_component	The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.
GO:1990062	RPAP3/R2TP/prefoldin-like complex	cellular_component	A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.
GO:1990063	Bam protein complex	cellular_component	Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.
GO:1990064	ground tissue pattern formation	biological_process	The regionalization process that gives rise to the patterning of the ground tissue.
GO:1990065	Dxr protein complex	cellular_component	A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
GO:1990066	energy quenching	biological_process	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.
GO:1990067	intrachromosomal DNA recombination	biological_process	The process of DNA recombination occurring within a single chromosome.
GO:1990068	seed dehydration	biological_process	The seed development process whose outcome is the drying of a maturing seed.
GO:1990069	stomatal opening	biological_process	The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
GO:1990070	TRAPPI protein complex	cellular_component	A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.
GO:1990071	TRAPPII protein complex	cellular_component	A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.
GO:1990072	TRAPPIII protein complex	cellular_component	A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.
GO:1990073	perforation plate	cellular_component	A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).
GO:1990074	polyuridylation-dependent mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.
GO:1990075	periciliary membrane compartment	cellular_component	A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.
GO:1990076	cell wall polysaccharide catabolic process involved in abscission	biological_process	Any cell wall polysaccharide catabolic process that is involved in abscission.
GO:1990077	primosome complex	cellular_component	Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.
GO:1990078	replication inhibiting complex	cellular_component	A protein complex that inhibits multiple events of replication initiation during one replication cycle.
GO:1990079	cartilage homeostasis	biological_process	A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.
GO:1990080	2-phenylethylamine receptor activity	molecular_function	Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.
GO:1990081	trimethylamine receptor activity	molecular_function	Combining with the biogenic amine trimethylamine to initiate a change in cell activity.
GO:1990082	DnaA-L2 complex	cellular_component	A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.
GO:1990083	DnaA-Hda complex	cellular_component	A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.
GO:1990084	DnaA-Dps complex	cellular_component	A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.
GO:1990085	Hda-beta clamp complex	cellular_component	A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.
GO:1990086	lens fiber cell apoptotic process	biological_process	Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
GO:1990088	[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase	molecular_function	Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+.
GO:1990089	response to nerve growth factor	biological_process	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
GO:1990090	cellular response to nerve growth factor stimulus	biological_process	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
GO:1990091	sodium-dependent self proteolysis	biological_process	The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
GO:1990092	calcium-dependent self proteolysis	biological_process	The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
GO:1990097	SeqA-DNA complex	cellular_component	A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle.
GO:1990098	core primosome complex	cellular_component	A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.
GO:1990099	pre-primosome complex	cellular_component	Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.
GO:1990100	DnaB-DnaC complex	cellular_component	A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).
GO:1990101	DnaA-oriC complex	cellular_component	A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.
GO:1990102	DnaA-DiaA complex	cellular_component	A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.
GO:1990103	DnaA-HU complex	cellular_component	A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.
GO:1990104	DNA bending complex	cellular_component	A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.
GO:1990107	thiazole synthase activity	molecular_function	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.
GO:1990108	protein linear deubiquitination	biological_process	A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.
GO:1990109	rejection of pollen from other species	biological_process	The recognition and rejection of pollen of one species by cells in the stigma of another species.
GO:1990110	callus formation	biological_process	The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
GO:1990111	spermatoproteasome complex	cellular_component	A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.
GO:1990112	RQC complex	cellular_component	A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
GO:1990113	RNA polymerase I assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.
GO:1990114	RNA polymerase II core complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
GO:1990115	RNA polymerase III assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.
GO:1990116	ribosome-associated ubiquitin-dependent protein catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.
GO:1990117	B cell receptor apoptotic signaling pathway	biological_process	An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.
GO:1990119	RNA helicase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of an RNA helicase.
GO:1990120	messenger ribonucleoprotein complex assembly	biological_process	The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
GO:1990121	H-NS complex	cellular_component	A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.
GO:1990124	messenger ribonucleoprotein complex	cellular_component	A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
GO:1990125	DiaA complex	cellular_component	A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.
GO:1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.
GO:1990130	GATOR1 complex	cellular_component	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.
GO:1990131	Gtr1-Gtr2 GTPase complex	cellular_component	A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.
GO:1990133	molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	cellular_component	A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved.
GO:1990134	epithelial cell apoptotic process involved in palatal shelf morphogenesis	biological_process	An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.
GO:1990135	flavonoid sulfotransferase activity	molecular_function	Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.
GO:1990136	linoleate 9S-lipoxygenase activity	molecular_function	Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
GO:1990137	plant seed peroxidase activity	molecular_function	Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH.
GO:1990138	neuron projection extension	biological_process	Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:1990139	protein localization to nuclear periphery	biological_process	A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.
GO:1990140	MPT synthase complex	cellular_component	A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
GO:1990143	CoA-synthesizing protein complex	cellular_component	A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway.
GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.
GO:1990145	maintenance of translational fidelity	biological_process	Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.
GO:1990146	protein localization to rhabdomere	biological_process	A process in which a protein is transported to, or maintained in, a location within a rhabdomere.
GO:1990147	talin binding	molecular_function	Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.
GO:1990148	glutamate dehydrogenase complex	cellular_component	A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.
GO:1990150	VEGF-A complex	cellular_component	A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.
GO:1990151	protein localization to cell tip	biological_process	A process in which a protein is transported to, or maintained in, a location at the cell tip.
GO:1990153	maintenance of protein localization to heterochromatin	biological_process	A process in which a protein is maintained in a location in telomeric heterochromatin.
GO:1990154	enzyme IIA-maltose transporter complex	cellular_component	A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.
GO:1990155	Dsc E3 ubiquitin ligase complex assembly	biological_process	The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.
GO:1990156	DnaB-DnaG complex	cellular_component	A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.
GO:1990157	DnaA-DnaB-DnaC complex	cellular_component	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.
GO:1990158	DnaB-DnaC-DnaT-PriA-PriB complex	cellular_component	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
GO:1990159	DnaB-DnaC-DnaT-PriA-PriC complex	cellular_component	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
GO:1990160	DnaB-DnaC-Rep-PriC complex	cellular_component	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
GO:1990161	DnaB helicase complex	cellular_component	A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.
GO:1990162	histone H3K4 deacetylase activity	molecular_function	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.
GO:1990165	single-strand break-containing DNA binding	molecular_function	Binding to damaged DNA containing single-strand breaks (SSBs).
GO:1990166	protein localization to site of double-strand break	biological_process	Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.
GO:1990167	protein K27-linked deubiquitination	biological_process	A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.
GO:1990168	protein K33-linked deubiquitination	biological_process	A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
GO:1990169	stress response to copper ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.
GO:1990170	stress response to cadmium ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.
GO:1990171	SCF complex disassembly in response to cadmium stress	biological_process	The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.
GO:1990172	G protein-coupled receptor catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.
GO:1990173	protein localization to nucleoplasm	biological_process	A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.
GO:1990174	phosphodiesterase decapping endonuclease activity	molecular_function	Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.
GO:1990175	EH domain binding	molecular_function	Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.
GO:1990176	MalFGK2 complex	cellular_component	Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.
GO:1990177	IHF-DNA complex	cellular_component	A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.
GO:1990178	HU-DNA complex	cellular_component	A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.
GO:1990179	protein localization to actomyosin contractile ring	biological_process	A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.
GO:1990180	mitochondrial tRNA 3'-end processing	biological_process	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
GO:1990181	acetyl-CoA biosynthetic process from pantothenate	biological_process	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.
GO:1990182	exosomal secretion	biological_process	The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
GO:1990183	lymphatic vascular process in circulatory system	biological_process	A circulatory process that occurs at the level of the lymphatic vasculature.
GO:1990184	amino acid transport complex	cellular_component	A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.
GO:1990185	regulation of lymphatic vascular permeability	biological_process	Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.
GO:1990186	regulation of lymphatic vessel size	biological_process	Any process that modulates the size of lymphatic vessels.
GO:1990188	euchromatin binding	molecular_function	Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.
GO:1990189	peptide-serine-alpha-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide.
GO:1990190	peptide-glutamate-alpha-N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.
GO:1990191	cobalamin transport complex	cellular_component	Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.
GO:1990192	collecting lymphatic vessel constriction	biological_process	A decrease in the diameter of collecting lymphatic vessels.
GO:1990193	BtuCD complex	cellular_component	Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.
GO:1990194	cytoplasmic U snRNP body assembly	biological_process	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.
GO:1990195	macrolide transmembrane transporter complex	cellular_component	A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.
GO:1990196	MacAB-TolC complex	cellular_component	The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.
GO:1990197	methionine-importing ABC transporter complex	cellular_component	An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner.
GO:1990198	ModE complex	cellular_component	A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.
GO:1990199	MsbA transporter complex	cellular_component	An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).
GO:1990200	SsuD-SsuE complex	cellular_component	A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.
GO:1990201	alkanesulfonate monooxygenase complex	cellular_component	A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.
GO:1990202	FMN reductase complex	cellular_component	A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.
GO:1990203	MdtBC Complex	cellular_component	A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.
GO:1990204	oxidoreductase complex	cellular_component	Any protein complex that possesses oxidoreductase activity.
GO:1990205	taurine dioxygenase complex	cellular_component	A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.
GO:1990206	jasmonyl-Ile conjugate hydrolase activity	molecular_function	Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.
GO:1990207	EmrE multidrug transporter complex	cellular_component	A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.
GO:1990210	positive regulation by symbiont of indole acetic acid levels in host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990211	positive regulation by symbiont of jasmonic acid levels in host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990212	positive regulation by symbiont of ethylene levels in host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990213	negative regulation by symbiont of salicylic acid levels in host	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990215	negative regulation by symbiont of host intracellular transport	biological_process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990216	positive regulation by symbiont of host transcription	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990217	suppression by symbiont of host phytoalexin production	biological_process	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990218	positive regulation by symbiont of abscisic acid levels in host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990220	GroEL-GroES complex	cellular_component	Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.
GO:1990221	L-cysteine desulfurase complex	cellular_component	A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer.
GO:1990222	ProVWX complex	cellular_component	The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions.
GO:1990223	positive regulation by symbiont of cytokinin levels in host	biological_process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO:1990224	NMN phosphatase activity	molecular_function	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.
GO:1990225	rhoptry neck	cellular_component	Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.
GO:1990226	histone methyltransferase binding	molecular_function	Binding to a histone methyltransferase enzyme.
GO:1990227	paranodal junction maintenance	biological_process	The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
GO:1990228	sulfurtransferase complex	cellular_component	A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).
GO:1990229	iron-sulfur cluster assembly complex	cellular_component	A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.
GO:1990230	iron-sulfur cluster transfer complex	cellular_component	A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).
GO:1990231	STING complex	cellular_component	A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.
GO:1990232	phosphomannomutase complex	cellular_component	A protein complex capable of phosphomannomutase activity.
GO:1990233	intramolecular phosphotransferase complex	cellular_component	A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.
GO:1990234	transferase complex	cellular_component	A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:1990235	diamine N-acetyltransferase complex	cellular_component	A protein complex which is capable of diamine N-acetyltransferase activity.
GO:1990236	proteasome core complex import into nucleus	biological_process	The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.
GO:1990238	double-stranded DNA endonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within a double-stranded DNA molecule by creating internal breaks.
GO:1990239	steroid hormone binding	molecular_function	Binding to a steroid hormone.
GO:1990243	atf1-pcr1 complex	cellular_component	A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).
GO:1990244	histone H2AT120 kinase activity	molecular_function	Catalysis of the reaction: histone H2A-threonine (position 120) + ATP = histone H2A-phosphothreonine (position 120) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 120 of histone H2A.
GO:1990246	uniplex complex	cellular_component	A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.
GO:1990247	N6-methyladenosine-containing RNA binding	molecular_function	Binding to an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.
GO:1990249	nucleotide-excision repair, DNA damage recognition complex	cellular_component	A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
GO:1990250	transcription-coupled nucleotide-excision repair, DNA damage recognition complex	cellular_component	A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
GO:1990251	nuclear exosome focus	cellular_component	An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.
GO:1990252	Syp1 complex	cellular_component	A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.
GO:1990253	cellular response to leucine starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
GO:1990254	keratin filament binding	molecular_function	Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.
GO:1990255	subsynaptic reticulum organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
GO:1990256	signal clustering	biological_process	Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.
GO:1990257	piccolo-bassoon transport vesicle	cellular_component	A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon.
GO:1990258	histone glutamine methylation	biological_process	The modification of a histone by addition of a methyl group to an glutamine residue.
GO:1990259	histone H2AQ104 methyltransferase activity	molecular_function	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-glutamine (position 104) = S-adenosyl-L-homocysteine + (histone H2A)-N5-methyl-glutamine (position 104). Note that this corresponds to  Q105 in yeast.
GO:1990261	pre-mRNA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).
GO:1990262	anti-Mullerian hormone signaling pathway	biological_process	The series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
GO:1990263	spore wall assembly MAPK cascade	biological_process	A MAPK cascade that occurs as a result of deprivation of nourishment.
GO:1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	biological_process	Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.
GO:1990265	platelet-derived growth factor complex	cellular_component	A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).
GO:1990266	neutrophil migration	biological_process	The movement of a neutrophil within or between different tissues and organs of the body.
GO:1990267	response to transition metal nanoparticle	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.
GO:1990268	response to gold nanoparticle	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.
GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding	molecular_function	Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II.
GO:1990270	platelet-derived growth factor receptor-ligand complex	cellular_component	A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes.
GO:1990272	anti-Mullerian hormone receptor activity	molecular_function	Combining with anti-Mullerian hormone to initiate a change in cell activity.
GO:1990273	snRNA capping	biological_process	The addition of a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA). Capping 7SK RNA stabilizes it.
GO:1990274	mitotic actomyosin contractile ring disassembly	biological_process	Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle.
GO:1990275	preribosome binding	molecular_function	Binding to a preribosome.
GO:1990276	RNA 5'-methyltransferase activity	molecular_function	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.
GO:1990277	parasexual reproduction with cellular fusion	biological_process	A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells.
GO:1990280	RNA localization to chromatin	biological_process	A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.
GO:1990281	efflux pump complex	cellular_component	A protein complex that is capable of efflux transmembrane transporter activity.
GO:1990294	peptidyl-threonine trans-autophosphorylation	biological_process	The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
GO:1990295	post-anaphase microtubule array	cellular_component	A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.
GO:1990297	renal amino acid absorption	biological_process	A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
GO:1990298	bub1-bub3 complex	cellular_component	Protein complex that associates with the kinetochores.
GO:1990299	Bub1-Bub3 complex localization to kinetochore	biological_process	A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.
GO:1990300	cellulosome binding	molecular_function	Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.
GO:1990302	Bre1-Rad6 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.
GO:1990303	UBR1-RAD6 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.
GO:1990304	MUB1-RAD6-UBR2 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.
GO:1990305	RAD6-UBR2 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.
GO:1990306	RSP5-BUL ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.
GO:1990308	type-I dockerin domain binding	molecular_function	Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.
GO:1990309	type-II dockerin domain binding	molecular_function	Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.
GO:1990310	type-III dockerin domain binding	molecular_function	Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.
GO:1990311	type-I cohesin domain binding	molecular_function	Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.
GO:1990312	type-II cohesin domain binding	molecular_function	Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.
GO:1990313	type-III cohesin domain binding	molecular_function	Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.
GO:1990314	cellular response to insulin-like growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
GO:1990315	Mcs4 RR-MAPKKK complex	cellular_component	A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
GO:1990316	Atg1/ULK1 kinase complex	cellular_component	A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
GO:1990317	Gin4 complex	cellular_component	A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.
GO:1990318	collagen type XIX trimer	cellular_component	A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells.
GO:1990319	collagen type XX trimer	cellular_component	A collagen homotrimer of alpha1(XX) chains.
GO:1990320	collagen type XXI trimer	cellular_component	A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
GO:1990321	collagen type XXII trimer	cellular_component	A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.
GO:1990322	collagen type XXIII trimer	cellular_component	A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.
GO:1990323	collagen type XXIV trimer	cellular_component	A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.
GO:1990324	collagen type XXVI trimer	cellular_component	A collagen homotrimer of alpha1(XXVI) chains.
GO:1990325	collagen type XXVII trimer	cellular_component	A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.
GO:1990326	collagen type XXVIII trimer	cellular_component	A collagen homotrimer of alpha1(XXVIII) chains.
GO:1990327	collagen type XXV trimer	cellular_component	A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.
GO:1990328	RPB4-RPB7 complex	cellular_component	A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.
GO:1990329	IscS-TusA complex	cellular_component	A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.
GO:1990330	IscS-IscU complex	cellular_component	A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.
GO:1990331	Hpa2 acetyltransferase complex	cellular_component	A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.
GO:1990332	Ire1 complex	cellular_component	A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript.
GO:1990333	mitotic checkpoint complex, CDC20-MAD2 subcomplex	cellular_component	A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
GO:1990334	Bfa1-Bub2 complex	cellular_component	A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.
GO:1990338	laminin-14 complex	cellular_component	A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.
GO:1990339	laminin-522 complex	cellular_component	A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.
GO:1990340	laminin-15 complex	cellular_component	A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.
GO:1990341	thrombospondin complex	cellular_component	A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.
GO:1990342	heterochromatin island	cellular_component	A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.
GO:1990343	heterochromatin domain	cellular_component	A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).
GO:1990344	secondary cell septum biogenesis	biological_process	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.
GO:1990346	BID-BCL-xl complex	cellular_component	A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
GO:1990349	gap junction-mediated intercellular transport	biological_process	The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.
GO:1990350	glucose transporter complex	cellular_component	A protein complex facilitating glucose transport into, out of or within a cell, or between cells.
GO:1990351	transporter complex	cellular_component	A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
GO:1990352	BRE1 E3 ubiquitin ligase complex	cellular_component	A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.
GO:1990353	Fused-Smurf ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.
GO:1990354	activated SUMO-E1 ligase complex	cellular_component	A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.
GO:1990355	L-methionine salvage from methionine sulphoxide	biological_process	The generation of L-methionine from methionine sulphoxide.
GO:1990357	terminal web	cellular_component	An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.
GO:1990358	xylanosome	cellular_component	A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.
GO:1990359	stress response to zinc ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.
GO:1990360	PKM2 protein kinase complex	cellular_component	A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.
GO:1990361	PKM2 pyruvate kinase complex	cellular_component	A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).
GO:1990362	butanol dehydrogenase activity	molecular_function	Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+.
GO:1990374	Kir2 inward rectifier potassium channel complex	cellular_component	A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.
GO:1990375	baculum development	biological_process	The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.
GO:1990377	organomineral extracellular matrix	cellular_component	An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.
GO:1990378	upstream stimulatory factor complex	cellular_component	A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.
GO:1990379	lipid transport across blood-brain barrier	biological_process	The directed movement of lipid molecules passing through the blood-brain barrier.
GO:1990380	K48-linked deubiquitinase activity	molecular_function	Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin.
GO:1990381	ubiquitin-specific protease binding	molecular_function	Binding to a ubiquitin-specific protease.
GO:1990383	cellular response to biotin starvation	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.
GO:1990384	hyaloid vascular plexus regression	biological_process	The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.
GO:1990385	meiotic spindle midzone	cellular_component	The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.
GO:1990386	mitotic cleavage furrow ingression	biological_process	Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
GO:1990387	isogloboside biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).
GO:1990388	xylem-to-phloem iron transport	biological_process	The directed movement of iron ions into the phloem from the xylem.
GO:1990389	CUE1-UBC7 ubiquitin-conjugating enzyme complex	cellular_component	A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.
GO:1990390	protein K33-linked ubiquitination	biological_process	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.
GO:1990391	DNA repair complex	cellular_component	A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:1990392	EFF-1 complex	cellular_component	A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.
GO:1990393	3M complex	cellular_component	A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.
GO:1990394	cellular response to cell wall damage	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.
GO:1990395	meiotic spindle pole body organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.
GO:1990396	single-strand break repair via homologous recombination	biological_process	The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
GO:1990397	queuosine salvage	biological_process	Any process which produces queuosine from derivatives of it, without de novo synthesis.
GO:1990398	Cus cation efflux complex	cellular_component	Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth.
GO:1990399	epithelium regeneration	biological_process	The regrowth of lost or destroyed epithelium.
GO:1990400	mitochondrial ribosomal large subunit rRNA binding	molecular_function	Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).
GO:1990401	embryonic lung development	biological_process	The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.
GO:1990402	embryonic liver development	biological_process	The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.
GO:1990403	embryonic brain development	biological_process	The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.
GO:1990404	NAD+-protein ADP-ribosyltransferase activity	molecular_function	Catalysis of the reaction: amino acyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-amino acyl-[protein] + nicotinamide.
GO:1990405	protein antigen binding	molecular_function	Binding to a protein antigen.
GO:1990406	CGRP receptor complex	cellular_component	A transmembrane, G protein-coupled signaling receptor complex recognized by calcitonin gene-related peptides (CGRP).
GO:1990407	calcitonin gene-related peptide binding	molecular_function	Binding to calcitonin gene-related peptide (CGRP).
GO:1990408	calcitonin gene-related peptide receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.
GO:1990409	adrenomedullin binding	molecular_function	Binding to adrenomedullin (AM).
GO:1990410	adrenomedullin receptor signaling pathway	biological_process	The series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.
GO:1990411	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)	molecular_function	Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.
GO:1990412	hercynylselenocysteine lyase activity (selenoneine-forming)	molecular_function	Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium.
GO:1990413	eyespot apparatus	cellular_component	A small pigmented organelle used in single-celled organisms to detect light.
GO:1990414	replication-born double-strand break repair via sister chromatid exchange	biological_process	The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.
GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	biological_process	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus.
GO:1990417	snoRNA release from pre-rRNA	biological_process	The release of snoRNA from pre-rRNA.
GO:1990418	response to insulin-like growth factor stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
GO:1990420	establishment of septation initiation network asymmetry	biological_process	The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.
GO:1990422	glyoxalase (glycolic acid-forming) activity	molecular_function	Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.
GO:1990423	RZZ complex	cellular_component	A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.
GO:1990424	protein arginine kinase activity	molecular_function	Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.
GO:1990425	ryanodine receptor complex	cellular_component	A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.
GO:1990426	mitotic recombination-dependent replication fork processing	biological_process	Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.
GO:1990427	stereocilia tip-link density	cellular_component	An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.
GO:1990428	miRNA transport	biological_process	The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:1990429	peroxisomal importomer complex	cellular_component	A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.
GO:1990430	extracellular matrix protein binding	molecular_function	Binding to a protein that is part of an extracellular matrix.
GO:1990431	priRNA 3'-end processing	biological_process	The process of forming the mature 3' end of a priRNA molecule.
GO:1990432	siRNA 3'-end processing	biological_process	The process of forming the mature 3' end of a siRNA molecule.
GO:1990433	CSL-Notch-Mastermind transcription factor complex	cellular_component	A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes.
GO:1990434	lower tip-link density	cellular_component	An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.
GO:1990435	upper tip-link density	cellular_component	An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.
GO:1990437	snRNA 2'-O-methylation	biological_process	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.
GO:1990438	U6 2'-O-snRNA methylation	biological_process	The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.
GO:1990439	MAP kinase serine/threonine phosphatase activity	molecular_function	Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	biological_process	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
GO:1990442	intrinsic apoptotic signaling pathway in response to nitrosative stress	biological_process	The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
GO:1990443	peptidyl-threonine autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.
GO:1990444	F-box domain binding	molecular_function	Binding to an F-box domain of a protein.
GO:1990446	U1 snRNP binding	molecular_function	Binding to a U1 small nuclear ribonucleoprotein particle.
GO:1990447	U2 snRNP binding	molecular_function	Binding to a U2 small nuclear ribonucleoprotein particle.
GO:1990448	exon-exon junction complex binding	molecular_function	Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
GO:1990450	linear polyubiquitin binding	molecular_function	Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.
GO:1990451	cellular stress response to acidic pH	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.
GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex	cellular_component	A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.
GO:1990453	nucleosome disassembly/reassembly complex	cellular_component	A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.
GO:1990454	L-type voltage-gated calcium channel complex	cellular_component	A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.
GO:1990455	PTEN phosphatase complex	cellular_component	A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.
GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering	biological_process	The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
GO:1990457	pexophagosome	cellular_component	A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.
GO:1990458	lipooligosaccharide binding	molecular_function	Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.
GO:1990459	transferrin receptor binding	molecular_function	Binding to a transferrin receptor.
GO:1990460	leptin receptor binding	molecular_function	Binding to a leptin receptor.
GO:1990461	detoxification of iron ion	biological_process	Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.
GO:1990462	omegasome	cellular_component	Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.
GO:1990463	lateral cortical node	cellular_component	A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins.
GO:1990464	D-2-hydroxyacid dehydrogenase (quinone) activity	molecular_function	Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol.
GO:1990465	aldehyde oxygenase (deformylating) activity	molecular_function	Catalysis of the reaction a long-chain aldehyde + O2 + 2 NADPH = an alkane + formate + H2O + 2 NADP+.
GO:1990466	protein autosumoylation	biological_process	The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
GO:1990467	NuA3a histone acetyltransferase complex	cellular_component	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.
GO:1990468	NuA3b histone acetyltransferase complex	cellular_component	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.
GO:1990469	Rhino-Deadlock-Cutoff Complex	cellular_component	Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.
GO:1990470	piRNA cluster binding	molecular_function	Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).
GO:1990471	piRNA uni-strand cluster binding	molecular_function	Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.
GO:1990472	piRNA dual-strand cluster binding	molecular_function	Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.
GO:1990473	ciliary targeting signal binding	molecular_function	Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.
GO:1990474	synaptic vesicle, readily releasable pool	cellular_component	A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.
GO:1990475	synaptic vesicle, recycling pool	cellular_component	A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state.
GO:1990476	synaptic vesicle, resting pool	cellular_component	A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.
GO:1990477	MTREC complex	cellular_component	Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex.
GO:1990478	response to ultrasound	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.
GO:1990481	mRNA pseudouridine synthesis	biological_process	The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.
GO:1990482	sphingolipid alpha-glucuronosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.
GO:1990483	Clr6 histone deacetylase complex I''	cellular_component	A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.
GO:1990484	aerobic lactate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.
GO:1990485	anaerobic lactate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.
GO:1990486	anaerobic fatty acid catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
GO:1990487	anaerobic lignin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.
GO:1990488	anaerobic cellulose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.
GO:1990489	anaerobic pectin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.
GO:1990490	archaeal proton-transporting A-type ATPase complex	cellular_component	A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.
GO:1990491	methane biosynthetic process from methanol and hydrogen	biological_process	The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.
GO:1990497	regulation of cytoplasmic translation in response to stress	biological_process	Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:1990498	mitotic spindle microtubule	cellular_component	Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.
GO:1990499	raps-insc complex	cellular_component	Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).
GO:1990500	eif4e-cup complex	cellular_component	A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.
GO:1990501	exon-exon junction subcomplex mago-y14	cellular_component	Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.
GO:1990502	dense core granule maturation	biological_process	Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.
GO:1990503	dendritic lamellar body	cellular_component	A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.
GO:1990504	dense core granule exocytosis	biological_process	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.
GO:1990505	mitotic DNA replication maintenance of fidelity	biological_process	Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication.
GO:1990506	mitotic DNA-templated DNA replication	biological_process	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.
GO:1990508	CKM complex	cellular_component	Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.
GO:1990509	PYM-mago-Y14 complex	cellular_component	Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans.
GO:1990512	Cry-Per complex	cellular_component	Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.
GO:1990513	CLOCK-BMAL transcription complex	cellular_component	Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.
GO:1990514	5' transitive RNA interference	biological_process	An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
GO:1990515	3' transitive RNA interference	biological_process	An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
GO:1990516	ribonucleotide excision repair	biological_process	The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.
GO:1990518	single-stranded 3'-5' DNA helicase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.
GO:1990519	pyrimidine nucleotide import into mitochondrion	biological_process	The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix.
GO:1990520	separase-securin complex	cellular_component	A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC).
GO:1990522	tail spike morphogenesis	biological_process	The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.
GO:1990523	bone regeneration	biological_process	The regrowth of bone following its loss or destruction.
GO:1990524	INA complex	cellular_component	A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.
GO:1990525	BIR domain binding	molecular_function	Binding to a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.
GO:1990526	Ste12p-Dig1p-Dig2p complex	cellular_component	A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.
GO:1990527	Tec1p-Ste12p-Dig1p complex	cellular_component	A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.
GO:1990528	Rvs161p-Rvs167p complex	cellular_component	A protein complex that is involved in endocytosis in the yeast S. cerevisiae.
GO:1990529	glycosylphosphatidylinositol-mannosyltransferase I complex	cellular_component	A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M.
GO:1990530	Cdc50p-Drs2p complex	cellular_component	A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.
GO:1990531	phospholipid-translocating ATPase complex	cellular_component	A protein complex that functions as a phospholipid-translocating P-Type ATPase.
GO:1990532	stress response to nickel ion	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.
GO:1990533	Dom34-Hbs1 complex	cellular_component	A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.
GO:1990534	thermospermine oxidase activity	molecular_function	Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.
GO:1990535	neuron projection maintenance	biological_process	The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:1990536	phosphoenolpyruvate transmembrane import into Golgi lumen	biological_process	The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.
GO:1990537	mitotic spindle polar microtubule	cellular_component	Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.
GO:1990538	xylan O-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.
GO:1990539	fructose import across plasma membrane	biological_process	The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
GO:1990540	mitochondrial manganese ion transmembrane transport	biological_process	The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990542	mitochondrial transmembrane transport	biological_process	The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.
GO:1990543	mitochondrial S-adenosyl-L-methionine transmembrane transport	biological_process	The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990544	mitochondrial ATP transmembrane transport	biological_process	The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990545	mitochondrial thiamine pyrophosphate transmembrane transport	biological_process	The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990546	mitochondrial tricarboxylic acid transmembrane transport	biological_process	The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990547	mitochondrial phosphate ion transmembrane transport	biological_process	The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990548	mitochondrial FAD transmembrane transport	biological_process	The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990549	mitochondrial NAD transmembrane transport	biological_process	The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990550	mitochondrial alpha-ketoglutarate transmembrane transport	biological_process	The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990551	mitochondrial 2-oxoadipate transmembrane transport	biological_process	The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990553	mitochondrial 5'-adenylyl sulfate transmembrane transport	biological_process	The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990554	mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport	biological_process	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990555	mitochondrial oxaloacetate transmembrane transport	biological_process	The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990556	mitochondrial isopropylmalate transmembrane transport	biological_process	The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990557	mitochondrial sulfate transmembrane transport	biological_process	The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990558	mitochondrial malonate(1-) transmembrane transport	biological_process	The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990559	mitochondrial coenzyme A transmembrane transport	biological_process	The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990562	syndecan-syntenin-ALIX complex	cellular_component	An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery.
GO:1990563	extracellular exosome complex	cellular_component	A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome.
GO:1990564	protein polyufmylation	biological_process	Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain.
GO:1990565	HSP90-CDC37 chaperone complex	cellular_component	A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signaling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins.
GO:1990566	I(KACh) inward rectifier potassium channel complex	cellular_component	An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.
GO:1990567	DPS complex	cellular_component	A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.
GO:1990569	UDP-N-acetylglucosamine transmembrane transport	biological_process	The process in which UDP-N-acetylglucosamine is transported across a membrane.
GO:1990570	GDP-mannose transmembrane transport	biological_process	The process in which GDP-mannose is transported across a membrane.
GO:1990571	meiotic centromere clustering	biological_process	The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I.
GO:1990572	TERT-RMRP complex	cellular_component	A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP).
GO:1990573	potassium ion import across plasma membrane	biological_process	The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.
GO:1990574	meiotic spindle astral microtubule	cellular_component	Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
GO:1990575	mitochondrial L-ornithine transmembrane transport	biological_process	The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion.
GO:1990576	G protein-coupled glucose receptor activity	molecular_function	Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:1990577	C-terminal protein demethylation	biological_process	The removal of a methyl group from the C-terminal amino acid of a protein.
GO:1990578	perinuclear endoplasmic reticulum membrane	cellular_component	The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.
GO:1990579	peptidyl-serine trans-autophosphorylation	biological_process	The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
GO:1990580	regulation of cytoplasmic translational termination	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.
GO:1990583	phospholipase D activator activity	molecular_function	Binds to and increases the activity of the enzyme phospholipase D.
GO:1990584	cardiac Troponin complex	cellular_component	A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.
GO:1990585	hydroxyproline O-arabinosyltransferase activity	molecular_function	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+.
GO:1990586	divisome complex	cellular_component	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells.
GO:1990587	FtsQBL complex	cellular_component	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ.
GO:1990588	FtsBL complex	cellular_component	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL.
GO:1990589	ATF4-CREB1 transcription factor complex	cellular_component	Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.
GO:1990590	ATF1-ATF4 transcription factor complex	cellular_component	Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.
GO:1990591	asparagine transmembrane import into vacuole	biological_process	The directed movement of asparagine into the vacuole across the vacuolar membrane.
GO:1990592	protein K69-linked ufmylation	biological_process	A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
GO:1990593	nascent polypeptide-associated complex binding	molecular_function	Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
GO:1990594	L-altrarate dehydratase activity	molecular_function	Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O.
GO:1990595	mast cell secretagogue receptor activity	molecular_function	Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.
GO:1990597	AIP1-IRE1 complex	cellular_component	A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein).
GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks.
GO:1990600	single-stranded DNA endodeoxyribonuclease activator activity	molecular_function	Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity.
GO:1990601	5' overhang single-stranded DNA endodeoxyribonuclease activity	molecular_function	Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.
GO:1990603	dark adaptation	biological_process	The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.
GO:1990604	IRE1-TRAF2-ASK1 complex	cellular_component	A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
GO:1990605	GU repeat RNA binding	molecular_function	Binding to an RNA molecule containing GU repeats.
GO:1990606	membrane scission GTPase motor activity	molecular_function	Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis.
GO:1990608	mitotic spindle pole body localization	biological_process	A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location.
GO:1990609	glutamate-cysteine ligase regulator activity	molecular_function	Binds to and modulates the activity of glutamate-cysteine ligase.
GO:1990610	acetolactate synthase regulator activity	molecular_function	Binds to and modulates the activity of acetolactate synthase.
GO:1990611	regulation of cytoplasmic translational initiation in response to stress	biological_process	Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:1990612	Sad1-Kms1 LINC complex	cellular_component	A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.
GO:1990615	Kelch-containing formin regulatory complex	cellular_component	A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.
GO:1990616	magnesium ion export from mitochondrion	biological_process	The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore.
GO:1990617	CHOP-ATF4 complex	cellular_component	A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.
GO:1990619	histone H3-K9 deacetylation	biological_process	The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone.
GO:1990620	ANPR-A receptor complex	cellular_component	A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure.
GO:1990621	ESCRT IV complex	cellular_component	An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.
GO:1990622	CHOP-ATF3 complex	cellular_component	A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.
GO:1990623	Herring body	cellular_component	The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively.
GO:1990624	guanyl nucleotide exchange factor inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.
GO:1990625	negative regulation of cytoplasmic translational initiation in response to stress	biological_process	Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.
GO:1990626	mitochondrial outer membrane fusion	biological_process	The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.
GO:1990627	mitochondrial inner membrane fusion	biological_process	The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.
GO:1990629	phospholamban complex	cellular_component	A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.
GO:1990630	IRE1-RACK1-PP2A complex	cellular_component	A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A.
GO:1990631	ErbB-4 class receptor binding	molecular_function	Binding to the protein-tyrosine kinase receptor ErbB-4/HER4.
GO:1990632	branching involved in submandibular gland morphogenesis	biological_process	The process in which the branching structure of the submandibular gland is generated and organized.
GO:1990633	mutator focus	cellular_component	A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.
GO:1990634	protein phosphatase 5 binding	molecular_function	Binding to protein phosphatase 5.
GO:1990635	proximal dendrite	cellular_component	The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma).
GO:1990636	reproductive senescence	biological_process	A life cycle stage during which the reproductive capacity and fitness of an organism declines.
GO:1990637	response to prolactin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.
GO:1990638	response to granulocyte colony-stimulating factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.
GO:1990640	inositol-2,4,5-triphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.
GO:1990641	response to iron ion starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.
GO:1990643	cellular response to granulocyte colony-stimulating factor	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.
GO:1990644	microtubule site clamp	molecular_function	The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.
GO:1990646	cellular response to prolactin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.
GO:1990647	C/EBP complex	cellular_component	A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities.
GO:1990648	inositol-4,5,6-triphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.
GO:1990649	inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.
GO:1990650	inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.
GO:1990651	inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity	molecular_function	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.
GO:1990654	sebum secreting cell proliferation	biological_process	The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.
GO:1990655	4 iron, 3 sulfur cluster binding	molecular_function	Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.
GO:1990656	t-SNARE clustering	biological_process	The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.
GO:1990657	iNOS-S100A8/A9 complex	cellular_component	A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.
GO:1990658	transnitrosylase complex	cellular_component	A transferase complex which is capable of transferring nitrogenous groups from one component to another.
GO:1990659	sequestering of manganese ion	biological_process	The process of binding or confining manganese ions such that they are separated from other components of a biological system.
GO:1990660	calprotectin complex	cellular_component	A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways.
GO:1990661	S100A8 complex	cellular_component	A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).
GO:1990662	S100A9 complex	cellular_component	A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.
GO:1990663	dihydroorotate dehydrogenase (fumarate) activity	molecular_function	Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.
GO:1990664	Nkx-2.5 complex	cellular_component	A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.
GO:1990665	AnxA2-p11 complex	cellular_component	A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).
GO:1990666	PCSK9-LDLR complex	cellular_component	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.
GO:1990667	PCSK9-AnxA2 complex	cellular_component	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2).
GO:1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	biological_process	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.
GO:1990669	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane	biological_process	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
GO:1990670	vesicle fusion with Golgi cis cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.
GO:1990671	vesicle fusion with Golgi medial cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.
GO:1990672	medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.
GO:1990674	Golgi cis cisterna membrane	cellular_component	The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.
GO:1990675	Golgi medial cisterna membrane	cellular_component	The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.
GO:1990676	Golgi trans cisterna membrane	cellular_component	The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.
GO:1990677	mitochondrial inner membrane assembly complex	cellular_component	A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.
GO:1990678	histone H4-K16 deacetylation	biological_process	The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone.
GO:1990679	histone H4-K12 deacetylation	biological_process	The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone.
GO:1990680	response to melanocyte-stimulating hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates.
GO:1990682	CSF1-CSF1R complex	cellular_component	A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.
GO:1990683	DNA double-strand break attachment to nuclear envelope	biological_process	A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.
GO:1990684	protein-lipid-RNA complex	cellular_component	A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.
GO:1990685	HDL-containing protein-lipid-RNA complex	cellular_component	A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.
GO:1990686	LDL-containing protein-lipid-RNA complex	cellular_component	A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.
GO:1990687	endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	biological_process	The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.
GO:1990688	Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	biological_process	The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
GO:1990689	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane	biological_process	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.
GO:1990690	Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
GO:1990691	cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.
GO:1990692	trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	biological_process	The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
GO:1990696	USH2 complex	cellular_component	A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.
GO:1990697	protein depalmitoleylation	biological_process	The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.
GO:1990698	palmitoleoyltransferase activity	molecular_function	Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.
GO:1990699	palmitoleyl hydrolase activity	molecular_function	Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.
GO:1990700	nucleolar chromatin organization	biological_process	Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.
GO:1990705	cholangiocyte proliferation	biological_process	The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.
GO:1990706	MAD1 complex	cellular_component	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).
GO:1990708	conditioned place preference	biological_process	The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.
GO:1990709	presynaptic active zone organization	biological_process	A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.
GO:1990710	MutS complex	cellular_component	A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.
GO:1990711	beta-catenin-ICAT complex	cellular_component	Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.
GO:1990712	HFE-transferrin receptor complex	cellular_component	A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.
GO:1990713	survivin complex	cellular_component	A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).
GO:1990714	hydroxyproline O-galactosyltransferase activity	molecular_function	Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.
GO:1990715	mRNA CDS binding	molecular_function	Binding to an mRNA molecule coding sequence (CDS).
GO:1990716	axonemal central apparatus	cellular_component	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules.
GO:1990717	axonemal central bridge	cellular_component	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.
GO:1990718	axonemal central pair projection	cellular_component	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.
GO:1990719	C1 axonemal microtubule	cellular_component	One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.
GO:1990720	C2 axonemal microtubule	cellular_component	One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.
GO:1990722	DAPK1-calmodulin complex	cellular_component	A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.
GO:1990723	cytoplasmic periphery of the nuclear pore complex	cellular_component	Cytoplasm situated in close proximity to a nuclear pore complex.
GO:1990724	galectin complex	cellular_component	A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.
GO:1990725	cord factor receptor activity	molecular_function	Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.
GO:1990726	Lsm1-7-Pat1 complex	cellular_component	A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.
GO:1990727	tubulin folding cofactor complex	cellular_component	A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.
GO:1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	cellular_component	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex.
GO:1990730	VCP-NSFL1C complex	cellular_component	A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.
GO:1990732	pyrenoid	cellular_component	A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.
GO:1990733	titin-telethonin complex	cellular_component	A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.
GO:1990734	astral microtubule anchoring at mitotic spindle pole body	biological_process	Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
GO:1990735	gamma-tubulin complex localization to mitotic spindle pole body	biological_process	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.
GO:1990736	regulation of vascular associated smooth muscle cell membrane depolarization	biological_process	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.
GO:1990737	response to manganese-induced endoplasmic reticulum stress	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.
GO:1990738	pseudouridine 5'-phosphatase activity	molecular_function	Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.
GO:1990739	granulosa cell proliferation	biological_process	The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.
GO:1990742	microvesicle	cellular_component	An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.
GO:1990743	protein sialylation	biological_process	A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.
GO:1990745	EARP complex	cellular_component	A quatrefoil tethering complex required for endocytic recycling.
GO:1990747	pancreatic trypsinogen secretion	biological_process	The regulated release of trypsinogen from the cells of the exocrine pancreas.
GO:1990748	cellular detoxification	biological_process	Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:1990749	polynucleotide adenylyltransferase activator activity	molecular_function	Increases the activity of the enzyme polynucleotide adenylyltransferase.
GO:1990751	Schwann cell chemotaxis	biological_process	The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:1990752	microtubule end	cellular_component	Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.
GO:1990753	equatorial cell cortex	cellular_component	The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.
GO:1990755	mitotic spindle microtubule depolymerization	biological_process	The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.
GO:1990756	ubiquitin ligase-substrate adaptor activity	molecular_function	The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
GO:1990757	ubiquitin ligase activator activity	molecular_function	Binds to and increases the activity of a ubiquitin ligase.
GO:1990758	mitotic sister chromatid biorientation	biological_process	The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.
GO:1990760	osmolarity-sensing monoatomic cation channel activity	molecular_function	Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.
GO:1990761	growth cone lamellipodium	cellular_component	A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.
GO:1990762	cytoplasmic alanyl-tRNA aminoacylation	biological_process	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.
GO:1990763	arrestin family protein binding	molecular_function	Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.
GO:1990764	myofibroblast contraction	biological_process	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.
GO:1990765	colon smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.
GO:1990767	prostaglandin receptor internalization	biological_process	The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.
GO:1990768	gastric mucosal blood circulation	biological_process	The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.
GO:1990769	proximal neuron projection	cellular_component	The portion of an axon or dendrite that is close to the neuronal cell body.
GO:1990770	small intestine smooth muscle contraction	biological_process	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.
GO:1990771	clathrin-dependent extracellular exosome endocytosis	biological_process	The clathrin-mediated endocytosis of an extracellular exosome.
GO:1990772	substance P secretion	biological_process	The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.
GO:1990773	matrix metallopeptidase secretion	biological_process	The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.
GO:1990775	endothelin production	biological_process	The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.
GO:1990776	response to angiotensin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.
GO:1990777	lipoprotein particle	cellular_component	A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.
GO:1990778	protein localization to cell periphery	biological_process	A process in which a protein is transported to, or maintained in, the cell periphery.
GO:1990779	glycoprotein Ib-IX-V complex	cellular_component	A transmembrane signaling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.
GO:1990780	cytoplasmic side of dendritic spine plasma membrane	cellular_component	The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine.
GO:1990781	response to immobilization stress combined with electrical stimulus	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.
GO:1990782	protein tyrosine kinase binding	molecular_function	Binding to protein tyrosine kinase.
GO:1990783	periphagosomal region of cytoplasm	cellular_component	Cytoplasm situated near, or occurring around, a phagosome.
GO:1990784	response to dsDNA	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
GO:1990785	response to water-immersion restraint stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.
GO:1990786	cellular response to dsDNA	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
GO:1990787	negative regulation of hh target transcription factor activity	biological_process	Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.
GO:1990788	GLI-SUFU complex	cellular_component	A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.
GO:1990789	thyroid gland epithelial cell proliferation	biological_process	The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population.
GO:1990790	response to glial cell derived neurotrophic factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.
GO:1990791	dorsal root ganglion development	biological_process	The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.
GO:1990792	cellular response to glial cell derived neurotrophic factor	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.
GO:1990793	substance P secretion, neurotransmission	biological_process	The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.
GO:1990794	basolateral part of cell	cellular_component	The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.
GO:1990795	rod bipolar cell terminal bouton	cellular_component	A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.
GO:1990796	photoreceptor cell terminal bouton	cellular_component	A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.
GO:1990798	pancreas regeneration	biological_process	The regrowth of a destroyed pancreas.
GO:1990799	mitochondrial tRNA wobble position uridine thiolation	biological_process	The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
GO:1990805	central cylinder	cellular_component	A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.
GO:1990806	ligand-gated ion channel signaling pathway	biological_process	The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.
GO:1990808	F-bar domain binding	molecular_function	Binding to an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins.
GO:1990809	endoplasmic reticulum tubular network membrane organization	biological_process	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.
GO:1990810	microtubule anchoring at mitotic spindle pole body	biological_process	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
GO:1990811	MWP complex	cellular_component	A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.
GO:1990812	growth cone filopodium	cellular_component	A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.
GO:1990813	meiotic centromeric cohesion protection in anaphase I	biological_process	The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I  after cohesin is cleaved by separase along the arm regions.
GO:1990814	DNA/DNA annealing activity	molecular_function	An activity that faciliates the formation of a complementary double-stranded DNA molecule.
GO:1990816	vacuole-mitochondrion membrane contact site	cellular_component	A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.
GO:1990817	poly(A) RNA polymerase activity	molecular_function	Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
GO:1990818	L-arginine transmembrane export from vacuole	biological_process	The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.
GO:1990819	mating projection actin fusion focus	cellular_component	A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
GO:1990820	response to mitotic DNA integrity checkpoint signaling	biological_process	A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.
GO:1990822	basic amino acid transmembrane transport	biological_process	The directed movement of basic amino acids from one side of a membrane to the other.
GO:1990823	response to leukemia inhibitory factor	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
GO:1990825	sequence-specific mRNA binding	molecular_function	Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
GO:1990826	nucleoplasmic periphery of the nuclear pore complex	cellular_component	Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.
GO:1990827	deaminase binding	molecular_function	Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).
GO:1990828	hepatocyte dedifferentiation	biological_process	The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
GO:1990829	C-rich single-stranded DNA binding	molecular_function	Binding to C-rich, single-stranded DNA.
GO:1990830	cellular response to leukemia inhibitory factor	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
GO:1990831	cellular response to carcinoembryonic antigen	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.
GO:1990832	slow axonal transport	biological_process	The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.
GO:1990833	clathrin-uncoating ATPase activity	molecular_function	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP.
GO:1990834	response to odorant	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
GO:1990836	lysosomal matrix	cellular_component	A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.
GO:1990837	sequence-specific double-stranded DNA binding	molecular_function	Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
GO:1990838	poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends	molecular_function	Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).
GO:1990839	response to endothelin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
GO:1990840	response to lectin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
GO:1990841	promoter-specific chromatin binding	molecular_function	Binding to a section of chromatin that is associated with gene promoter sequences of DNA.
GO:1990845	adaptive thermogenesis	biological_process	The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.
GO:1990846	ribonucleoside-diphosphate reductase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.
GO:1990849	vacuolar localization	biological_process	Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.
GO:1990850	H-gal-GP complex	cellular_component	A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.
GO:1990851	Wnt-Frizzled-LRP5/6 complex	cellular_component	A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.
GO:1990852	protein transport along microtubule to spindle pole body	biological_process	The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.
GO:1990854	vacuole-ER tethering	biological_process	The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.
GO:1990856	methionyl-initiator methionine tRNA binding	molecular_function	Binding to methionine-initator methionine tRNA.
GO:1990858	cellular response to lectin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
GO:1990859	cellular response to endothelin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
GO:1990860	Pho85-Pho80 CDK-cyclin complex	cellular_component	A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
GO:1990861	Ubp3-Bre5 deubiquitination complex	cellular_component	A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.
GO:1990862	nuclear membrane complex Bqt3-Bqt4	cellular_component	A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.
GO:1990863	acinar cell proliferation	biological_process	The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).
GO:1990864	response to growth hormone-releasing hormone	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.
GO:1990867	response to gastrin	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
GO:1990868	response to chemokine	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
GO:1990869	cellular response to chemokine	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
GO:1990871	Vma12-Vma22 assembly complex	cellular_component	A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.
GO:1990874	vascular associated smooth muscle cell proliferation	biological_process	The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
GO:1990875	nucleoplasmic side of nuclear pore	cellular_component	The side of the nuclear pore complex (NPC) that faces the nucleoplasm.
GO:1990876	cytoplasmic side of nuclear pore	cellular_component	The side of the nuclear pore complex (NPC) that faces the cytoplasm.
GO:1990877	FNIP-folliculin RagC/D GAP	cellular_component	A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.
GO:1990878	cellular response to gastrin	biological_process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
GO:1990879	CST complex	cellular_component	A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
GO:1990880	cellular detoxification of copper ion	biological_process	Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
GO:1990882	rRNA acetylation	biological_process	The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
GO:1990883	rRNA cytidine N-acetyltransferase activity	molecular_function	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA.
GO:1990884	RNA acetylation	biological_process	The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.
GO:1990887	2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity	molecular_function	Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+.
GO:1990888	2-polyprenyl-6-hydroxyphenol O-methyltransferase activity	molecular_function	Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.
GO:1990889	H4K20me3 modified histone binding	molecular_function	Binding to a histone H4 in which the lysine residue at position 20 has been modified by trimethylation.
GO:1990890	netrin receptor binding	molecular_function	Binding to a netrin receptor.
GO:1990891	mitotic sister chromatid arm separation	biological_process	The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.
GO:1990892	mitotic chromosome arm condensation	biological_process	The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
GO:1990893	mitotic chromosome centromere condensation	biological_process	The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.
GO:1990895	regulation of protein localization to cell cortex of cell tip	biological_process	Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.
GO:1990896	protein localization to cell cortex of cell tip	biological_process	A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.
GO:1990900	ciliary pocket collar	cellular_component	A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.
GO:1990901	old cell pole	cellular_component	The cell pole distal from the most recent cell division.
GO:1990902	new cell pole	cellular_component	The cell pole proximal to the most recent cell division.
GO:1990904	ribonucleoprotein complex	cellular_component	A macromolecular complex that contains both RNA and protein molecules.
GO:1990905	dinoflagellate peduncle	cellular_component	A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).
GO:1990906	accessory outer segment	cellular_component	A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.
GO:1990907	beta-catenin-TCF complex	cellular_component	A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
GO:1990909	Wnt signalosome	cellular_component	A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.
GO:1990910	response to hypobaric hypoxia	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).
GO:1990911	response to psychosocial stress	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.
GO:1990913	sperm head plasma membrane	cellular_component	The plasma membrane that is part of the head section of a sperm cell.
GO:1990915	structural constituent of ascospore wall	molecular_function	The action of a molecule that contributes to the structural integrity of an ascospore wall.
GO:1990916	Isp3 layer of spore wall	cellular_component	The outermost layers of the spore wall, as described in Schizosaccharomyces pombe.
GO:1990917	ooplasm	cellular_component	The cytoplasm of an ovum.
GO:1990918	double-strand break repair involved in meiotic recombination	biological_process	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.
GO:1990919	proteasome-nuclear membrane anchor activity	molecular_function	The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome.
GO:1990922	hepatic stellate cell proliferation	biological_process	The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.
GO:1990923	PET complex	cellular_component	A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs.
GO:1990926	short-term synaptic potentiation	biological_process	The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds.
GO:1990927	calcium ion regulated lysosome exocytosis	biological_process	The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
GO:1990928	response to amino acid starvation	biological_process	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
GO:1990929	sulfoquinovosidase activity	molecular_function	Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose.
GO:1990930	mRNA N1-methyladenosine dioxygenase activity	molecular_function	Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.
GO:1990931	mRNA N6-methyladenosine dioxygenase activity	molecular_function	Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.
GO:1990932	5.8S rRNA binding	molecular_function	Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.
GO:1990933	microtubule cytoskeleton attachment to nuclear envelope	biological_process	A process in which the microtubule cytoskeleton is attached to the nuclear envelope.
GO:1990934	nucleolus-like body	cellular_component	A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.
GO:1990935	splicing factor binding	molecular_function	Binding to a protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA.
GO:1990936	vascular associated smooth muscle cell dedifferentiation	biological_process	The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
GO:1990937	xylan acetylation	biological_process	The addition of one or more acetyl groups to a xylan molecule.
GO:1990938	peptidyl-aspartic acid autophosphorylation	biological_process	The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.
GO:1990941	mitotic spindle kinetochore microtubule	cellular_component	Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation.
GO:1990942	mitotic metaphase chromosome recapture	biological_process	A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.
GO:1990943	mating type region replication fork barrier binding	molecular_function	Binding to the replication fork barrier found in the mating type region of fission yeast.
GO:1990946	meiosis I/meiosis II transition	biological_process	The cell cycle process in which a cell progresses from meiosis I to meiosis II.
GO:1990947	exit from meiosis	biological_process	Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half.
GO:1990948	ubiquitin ligase inhibitor activity	molecular_function	Binds to and stops, prevents or reduces the activity of a ubiquitin ligase.
GO:1990949	metaphase/anaphase transition of meiosis I	biological_process	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.
GO:1990950	metaphase/anaphase transition of meiosis II	biological_process	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II.
GO:1990953	intramanchette transport	biological_process	The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.
GO:1990955	G-rich single-stranded DNA binding	molecular_function	Binding to G-rich, single-stranded DNA.
GO:1990956	fibroblast chemotaxis	biological_process	The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:1990957	NPHP complex	cellular_component	A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.
GO:1990959	eosinophil homeostasis	biological_process	The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:1990960	basophil homeostasis	biological_process	The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	biological_process	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.
GO:1990962	xenobiotic transport across blood-brain barrier	biological_process	The directed movement of a xenobiotic through the blood-brain barrier.
GO:1990963	establishment of blood-retinal barrier	biological_process	Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.
GO:1990964	actin cytoskeleton-regulatory complex	cellular_component	A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat.
GO:1990965	cytosylglucuronate decarboxylase activity	molecular_function	Catalysis of the reaction: cytosylglucuronic acid + H+ = cytosylarabinopyranose + CO2.
GO:1990966	ATP generation from poly-ADP-D-ribose	biological_process	The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
GO:1990968	modulation by host of RNA binding by virus	biological_process	A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.
GO:1990969	modulation by host of viral RNA-binding transcription factor activity	biological_process	A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.
GO:1990970	trans-activation response element binding	molecular_function	Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.
GO:1990971	EMILIN complex	cellular_component	Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.
GO:1990972	multimerin complex	cellular_component	Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.
GO:1990973	transmembrane actin-associated (TAN) line	cellular_component	A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).
GO:1990974	actin-dependent nuclear migration	biological_process	The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.
GO:1990976	protein transport along microtubule to mitotic spindle pole body	biological_process	The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.
GO:1990983	tRNA demethylation	biological_process	The removal of a methyl group from one or more residues within a tRNA molecule.
GO:1990984	tRNA demethylase activity	molecular_function	Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule.
GO:1990986	DNA recombinase disassembly	biological_process	The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).
GO:2000001	regulation of DNA damage checkpoint	biological_process	Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.
GO:2000002	negative regulation of DNA damage checkpoint	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.
GO:2000003	positive regulation of DNA damage checkpoint	biological_process	Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.
GO:2000004	regulation of metanephric S-shaped body morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.
GO:2000006	regulation of metanephric comma-shaped body morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.
GO:2000008	regulation of protein localization to cell surface	biological_process	Any process that modulates the frequency, rate or extent of protein localization to the cell surface.
GO:2000009	negative regulation of protein localization to cell surface	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.
GO:2000010	positive regulation of protein localization to cell surface	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.
GO:2000011	regulation of adaxial/abaxial pattern formation	biological_process	Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.
GO:2000012	regulation of auxin polar transport	biological_process	Any process that modulates the frequency, rate or extent of auxin polar transport.
GO:2000013	regulation of arginine biosynthetic process via ornithine	biological_process	Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine.
GO:2000014	regulation of endosperm development	biological_process	Any process that modulates the frequency, rate or extent of endosperm development.
GO:2000015	regulation of determination of dorsal identity	biological_process	Any process that modulates the frequency, rate or extent of determination of dorsal identity.
GO:2000016	negative regulation of determination of dorsal identity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
GO:2000017	positive regulation of determination of dorsal identity	biological_process	Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.
GO:2000018	regulation of male gonad development	biological_process	Any process that modulates the frequency, rate or extent of male gonad development.
GO:2000019	negative regulation of male gonad development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.
GO:2000020	positive regulation of male gonad development	biological_process	Any process that activates or increases the frequency, rate or extent of male gonad development.
GO:2000022	regulation of jasmonic acid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.
GO:2000023	regulation of lateral root development	biological_process	Any process that modulates the frequency, rate or extent of lateral root development.
GO:2000024	regulation of leaf development	biological_process	Any process that modulates the frequency, rate or extent of leaf development.
GO:2000025	regulation of leaf formation	biological_process	Any process that modulates the frequency, rate or extent of leaf formation.
GO:2000026	regulation of multicellular organismal development	biological_process	Any process that modulates the frequency, rate or extent of multicellular organismal development.
GO:2000027	regulation of animal organ morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of animal organ morphogenesis.
GO:2000028	regulation of photoperiodism, flowering	biological_process	Any process that modulates the frequency, rate or extent of photoperiodism, flowering.
GO:2000029	regulation of proanthocyanidin biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.
GO:2000030	regulation of response to red or far red light	biological_process	Any process that modulates the frequency, rate or extent of response to red or far red light.
GO:2000031	regulation of salicylic acid mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.
GO:2000032	regulation of secondary shoot formation	biological_process	Any process that modulates the frequency, rate or extent of secondary shoot formation.
GO:2000033	regulation of seed dormancy process	biological_process	Any process that modulates the frequency, rate or extent of seed dormancy process.
GO:2000034	regulation of seed maturation	biological_process	Any process that modulates the frequency, rate or extent of seed maturation.
GO:2000035	regulation of stem cell division	biological_process	Any process that modulates the frequency, rate or extent of stem cell division.
GO:2000036	regulation of stem cell population maintenance	biological_process	Any process that modulates the frequency, rate or extent of stem cell population maintenance.
GO:2000037	regulation of stomatal complex patterning	biological_process	Any process that modulates the frequency, rate or extent of stomatal complex patterning.
GO:2000038	regulation of stomatal complex development	biological_process	Any process that modulates the frequency, rate or extent of stomatal complex development.
GO:2000039	regulation of trichome morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of trichome morphogenesis.
GO:2000040	regulation of planar cell polarity pathway involved in axis elongation	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.
GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.
GO:2000042	negative regulation of double-strand break repair via homologous recombination	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.
GO:2000043	regulation of cardiac cell fate specification	biological_process	Any process that modulates the frequency, rate or extent of cardiac cell fate specification.
GO:2000044	negative regulation of cardiac cell fate specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.
GO:2000045	regulation of G1/S transition of mitotic cell cycle	biological_process	Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	biological_process	Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	biological_process	Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
GO:2000050	regulation of non-canonical Wnt signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway.
GO:2000051	negative regulation of non-canonical Wnt signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway.
GO:2000052	positive regulation of non-canonical Wnt signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.
GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	biological_process	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
GO:2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	biological_process	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
GO:2000056	regulation of Wnt signaling pathway involved in digestive tract morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.
GO:2000057	negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	biological_process	Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
GO:2000061	regulation of ureter smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.
GO:2000064	regulation of cortisol biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of cortisol biosynthetic process.
GO:2000065	negative regulation of cortisol biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.
GO:2000066	positive regulation of cortisol biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.
GO:2000067	regulation of root morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of root morphogenesis.
GO:2000068	regulation of defense response to insect	biological_process	Any process that modulates the frequency, rate or extent of defense response to insect.
GO:2000069	regulation of post-embryonic root development	biological_process	Any process that modulates the frequency, rate or extent of post-embryonic root development.
GO:2000070	regulation of response to water deprivation	biological_process	Any process that modulates the frequency, rate or extent of response to water deprivation.
GO:2000071	regulation of defense response by callose deposition	biological_process	Any process that modulates the frequency, rate or extent of defense response by callose deposition.
GO:2000073	regulation of cytokinesis, site selection	biological_process	Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.
GO:2000074	regulation of type B pancreatic cell development	biological_process	Any process that modulates the frequency, rate or extent of pancreatic B cell development.
GO:2000075	negative regulation of cytokinesis, site selection	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.
GO:2000076	positive regulation of cytokinesis, site selection	biological_process	Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.
GO:2000077	negative regulation of type B pancreatic cell development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.
GO:2000078	positive regulation of type B pancreatic cell development	biological_process	Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.
GO:2000079	regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
GO:2000080	negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
GO:2000081	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
GO:2000082	regulation of L-ascorbic acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.
GO:2000083	negative regulation of L-ascorbic acid biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.
GO:2000084	regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
GO:2000085	negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
GO:2000086	positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
GO:2000087	regulation of mesonephric glomerulus development	biological_process	Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.
GO:2000088	negative regulation of mesonephric glomerulus development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.
GO:2000089	positive regulation of mesonephric glomerulus development	biological_process	Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.
GO:2000090	regulation of mesonephric glomerular mesangial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
GO:2000091	negative regulation of mesonephric glomerular mesangial cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
GO:2000092	positive regulation of mesonephric glomerular mesangial cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
GO:2000093	regulation of mesonephric nephron tubule epithelial cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.
GO:2000094	negative regulation of mesonephric nephron tubule epithelial cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	biological_process	Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	biological_process	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
GO:2000097	regulation of smooth muscle cell-matrix adhesion	biological_process	Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.
GO:2000099	regulation of establishment or maintenance of bipolar cell polarity	biological_process	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity.
GO:2000100	regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
GO:2000101	regulation of mammary stem cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of mammary stem cell proliferation.
GO:2000102	negative regulation of mammary stem cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation.
GO:2000103	positive regulation of mammary stem cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation.
GO:2000104	negative regulation of DNA-templated DNA replication	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.
GO:2000105	positive regulation of DNA-templated DNA replication	biological_process	Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.
GO:2000106	regulation of leukocyte apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.
GO:2000107	negative regulation of leukocyte apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.
GO:2000108	positive regulation of leukocyte apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.
GO:2000109	regulation of macrophage apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of macrophage apoptotic process.
GO:2000110	negative regulation of macrophage apoptotic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.
GO:2000111	positive regulation of macrophage apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.
GO:2000114	regulation of establishment of cell polarity	biological_process	Any process that modulates the frequency, rate or extent of establishment of cell polarity.
GO:2000115	regulation of maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.
GO:2000116	regulation of cysteine-type endopeptidase activity	biological_process	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity.
GO:2000117	negative regulation of cysteine-type endopeptidase activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.
GO:2000118	regulation of sodium-dependent phosphate transport	biological_process	Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport.
GO:2000119	negative regulation of sodium-dependent phosphate transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.
GO:2000120	positive regulation of sodium-dependent phosphate transport	biological_process	Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport.
GO:2000121	regulation of removal of superoxide radicals	biological_process	Any process that modulates the frequency, rate or extent of removal of superoxide radicals.
GO:2000122	negative regulation of stomatal complex development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.
GO:2000123	positive regulation of stomatal complex development	biological_process	Any process that activates or increases the frequency, rate or extent of stomatal complex development.
GO:2000124	regulation of endocannabinoid signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.
GO:2000125	regulation of octopamine or tyramine signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.
GO:2000126	negative regulation of octopamine or tyramine signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway.
GO:2000127	positive regulation of octopamine or tyramine signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.
GO:2000128	regulation of octopamine signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of octopamine signaling pathway.
GO:2000129	negative regulation of octopamine signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.
GO:2000130	positive regulation of octopamine signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.
GO:2000131	regulation of tyramine signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of tyramine signaling pathway.
GO:2000132	negative regulation of tyramine signaling pathway	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.
GO:2000133	positive regulation of tyramine signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	biological_process	Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
GO:2000139	regulation of octopamine signaling pathway involved in response to food	biological_process	Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.
GO:2000140	negative regulation of octopamine signaling pathway involved in response to food	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food.
GO:2000141	positive regulation of octopamine signaling pathway involved in response to food	biological_process	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.
GO:2000142	regulation of DNA-templated transcription initiation	biological_process	Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.
GO:2000143	negative regulation of DNA-templated transcription initiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.
GO:2000144	positive regulation of DNA-templated transcription initiation	biological_process	Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
GO:2000145	regulation of cell motility	biological_process	Any process that modulates the frequency, rate or extent of cell motility.
GO:2000146	negative regulation of cell motility	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
GO:2000147	positive regulation of cell motility	biological_process	Any process that activates or increases the frequency, rate or extent of cell motility.
GO:2000148	regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.
GO:2000150	regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.
GO:2000152	regulation of ubiquitin-specific protease activity	biological_process	Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity.
GO:2000155	positive regulation of cilium-dependent cell motility	biological_process	Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.
GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER	biological_process	Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.
GO:2000157	negative regulation of ubiquitin-specific protease activity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
GO:2000158	positive regulation of ubiquitin-specific protease activity	biological_process	Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
GO:2000159	regulation of planar cell polarity pathway involved in heart morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.
GO:2000160	negative regulation of planar cell polarity pathway involved in heart morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.
GO:2000161	regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.
GO:2000163	regulation of planar cell polarity pathway involved in outflow tract morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.
GO:2000165	regulation of planar cell polarity pathway involved in pericardium morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.
GO:2000167	regulation of planar cell polarity pathway involved in neural tube closure	biological_process	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.
GO:2000169	regulation of peptidyl-cysteine S-nitrosylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation	biological_process	Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
GO:2000171	negative regulation of dendrite development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.
GO:2000172	regulation of branching morphogenesis of a nerve	biological_process	Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.
GO:2000173	negative regulation of branching morphogenesis of a nerve	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.
GO:2000174	regulation of pro-T cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of pro-T cell differentiation.
GO:2000175	negative regulation of pro-T cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.
GO:2000176	positive regulation of pro-T cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.
GO:2000177	regulation of neural precursor cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.
GO:2000178	negative regulation of neural precursor cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.
GO:2000179	positive regulation of neural precursor cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
GO:2000180	negative regulation of androgen biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.
GO:2000181	negative regulation of blood vessel morphogenesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.
GO:2000182	regulation of progesterone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.
GO:2000183	negative regulation of progesterone biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.
GO:2000184	positive regulation of progesterone biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.
GO:2000185	regulation of phosphate transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.
GO:2000186	negative regulation of phosphate transmembrane transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
GO:2000187	positive regulation of phosphate transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.
GO:2000191	regulation of fatty acid transport	biological_process	Any process that modulates the frequency, rate or extent of fatty acid transport.
GO:2000192	negative regulation of fatty acid transport	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.
GO:2000193	positive regulation of fatty acid transport	biological_process	Any process that activates or increases the frequency, rate or extent of fatty acid transport.
GO:2000194	regulation of female gonad development	biological_process	Any process that modulates the frequency, rate or extent of female gonad development.
GO:2000195	negative regulation of female gonad development	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.
GO:2000196	positive regulation of female gonad development	biological_process	Any process that activates or increases the frequency, rate or extent of female gonad development.
GO:2000197	regulation of ribonucleoprotein complex localization	biological_process	Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization.
GO:2000198	negative regulation of ribonucleoprotein complex localization	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.
GO:2000199	positive regulation of ribonucleoprotein complex localization	biological_process	Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization.
GO:2000200	regulation of ribosomal subunit export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.
GO:2000201	negative regulation of ribosomal subunit export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus.
GO:2000202	positive regulation of ribosomal subunit export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus.
GO:2000203	regulation of ribosomal large subunit export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus.
GO:2000204	negative regulation of ribosomal large subunit export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.
GO:2000205	positive regulation of ribosomal large subunit export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.
GO:2000206	regulation of ribosomal small subunit export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.
GO:2000207	negative regulation of ribosomal small subunit export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.
GO:2000208	positive regulation of ribosomal small subunit export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.
GO:2000209	regulation of anoikis	biological_process	Any process that modulates the frequency, rate or extent of anoikis.
GO:2000210	positive regulation of anoikis	biological_process	Any process that activates or increases the frequency, rate or extent of anoikis.
GO:2000211	regulation of glutamate metabolic process	biological_process	Any process that modulates the frequency, rate or extent of glutamate metabolic process.
GO:2000212	negative regulation of glutamate metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.
GO:2000213	positive regulation of glutamate metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.
GO:2000214	regulation of proline metabolic process	biological_process	Any process that modulates the frequency, rate or extent of proline metabolic process.
GO:2000215	negative regulation of proline metabolic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process.
GO:2000216	positive regulation of proline metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of proline metabolic process.
GO:2000217	regulation of invasive growth in response to glucose limitation	biological_process	Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.
GO:2000218	negative regulation of invasive growth in response to glucose limitation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.
GO:2000219	positive regulation of invasive growth in response to glucose limitation	biological_process	Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.
GO:2000220	regulation of pseudohyphal growth	biological_process	Any process that modulates the frequency, rate or extent of pseudohyphal growth.
GO:2000221	negative regulation of pseudohyphal growth	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.
GO:2000222	positive regulation of pseudohyphal growth	biological_process	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.
GO:2000224	regulation of testosterone biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.
GO:2000225	negative regulation of testosterone biosynthetic process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.
GO:2000226	regulation of pancreatic A cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.
GO:2000227	negative regulation of pancreatic A cell differentiation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.
GO:2000228	positive regulation of pancreatic A cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.
GO:2000229	regulation of pancreatic stellate cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.
GO:2000230	negative regulation of pancreatic stellate cell proliferation	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.
GO:2000231	positive regulation of pancreatic stellate cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.
GO:2000232	regulation of rRNA processing	biological_process	Any process that modulates the frequency, rate or extent of rRNA processing.
GO:2000233	negative regulation of rRNA processing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.
GO:2000234	positive regulation of rRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of rRNA processing.
GO:2000235	regulation of tRNA processing	biological_process	Any process that modulates the frequency, rate or extent of tRNA processing.
GO:2000236	negative regulation of tRNA processing	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.
GO:2000237	positive regulation of tRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA processing.
GO:2000238	regulation of tRNA export from nucleus	biological_process	Any process that modulates the frequency, rate or extent of tRNA export from nucleus.
GO:2000239	negative regulation of tRNA export from nucleus	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.
GO:2000240	positive regulation of tRNA export from nucleus	biological_process	Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus.
GO:2000241	regulation of reproductive process	biological_process	Any process that modulates the frequency, rate or extent of reproductive process.
GO:2000242	negative regulation of reproductive process	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.
GO:2000243	positive regulation of reproductive process	biological_process	Any process that activates or increases the frequency, rate or extent of reproductive process.
GO:2000244	regulation of FtsZ-dependent cytokinesis	biological_process	Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.
GO:2000245	negative regulation of FtsZ-dependent cytokinesis	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.
GO:2000246	positive regulation of FtsZ-dependent cytokinesis	biological_process	Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis.
GO:2000247	positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
GO:2000248	negative regulation of establishment or maintenance of neuroblast polarity	biological_process	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.
GO:2000252	negative regulation of feeding behavior	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
GO:2000253	positive regulation of feeding behavior	biological_process	Any process that activates or increases the frequency, rate or extent of feeding behavior.
GO:2000254	regulation of male germ cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of male germ cell proliferation.
GO:2000255	negative regulation of male germ cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.
GO:2000256	positive regulation of male germ cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.
GO:2000257	regulation of protein activation cascade	biological_process	Any process that modulates the frequency, rate or extent of protein activation cascade.
GO:2000258	negative regulation of protein activation cascade	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade.
GO:2000259	positive regulation of protein activation cascade	biological_process	Any process that activates or increases the frequency, rate or extent of protein activation cascade.
GO:2000260	regulation of blood coagulation, common pathway	biological_process	Any process that modulates the frequency, rate or extent of blood coagulation, common pathway.
GO:2000261	negative regulation of blood coagulation, common pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway.
GO:2000262	positive regulation of blood coagulation, common pathway	biological_process	Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway.
GO:2000263	regulation of blood coagulation, extrinsic pathway	biological_process	Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway.
GO:2000264	negative regulation of blood coagulation, extrinsic pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway.
GO:2000265	positive regulation of blood coagulation, extrinsic pathway	biological_process	Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway.
GO:2000266	regulation of blood coagulation, intrinsic pathway	biological_process	Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.
GO:2000267	negative regulation of blood coagulation, intrinsic pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway.
GO:2000268	positive regulation of blood coagulation, intrinsic pathway	biological_process	Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway.
GO:2000269	regulation of fibroblast apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.
GO:2000270	negative regulation of fibroblast apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.
GO:2000271	positive regulation of fibroblast apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.
GO:2000272	negative regulation of signaling receptor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.
GO:2000273	positive regulation of signaling receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of signaling receptor activity.
GO:2000274	regulation of epithelial cell migration, open tracheal system	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	biological_process	Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	biological_process	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
GO:2000278	regulation of DNA biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
GO:2000279	negative regulation of DNA biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.
GO:2000280	regulation of root development	biological_process	Any process that modulates the frequency, rate or extent of root development.
GO:2000282	regulation of cellular amino acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.
GO:2000283	negative regulation of amino acid biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process.
GO:2000284	positive regulation of amino acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.
GO:2000286	receptor internalization involved in canonical Wnt signaling pathway	biological_process	A receptor internalization process that contributes to canonical Wnt signaling pathway.
GO:2000287	positive regulation of myotome development	biological_process	Any process that activates or increases the frequency, rate or extent of myotome development.
GO:2000288	positive regulation of myoblast proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of myoblast proliferation.
GO:2000289	regulation of photoreceptor cell axon guidance	biological_process	Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance.
GO:2000290	regulation of myotome development	biological_process	Any process that modulates the frequency, rate or extent of myotome development.
GO:2000291	regulation of myoblast proliferation	biological_process	Any process that modulates the frequency, rate or extent of myoblast proliferation.
GO:2000292	regulation of defecation	biological_process	Any process that modulates the frequency, rate or extent of defecation.
GO:2000293	negative regulation of defecation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of defecation.
GO:2000294	positive regulation of defecation	biological_process	Any process that activates or increases the frequency, rate or extent of defecation.
GO:2000295	regulation of hydrogen peroxide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.
GO:2000296	negative regulation of hydrogen peroxide catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.
GO:2000297	negative regulation of synapse maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.
GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity	biological_process	Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
GO:2000300	regulation of synaptic vesicle exocytosis	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
GO:2000301	negative regulation of synaptic vesicle exocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.
GO:2000302	positive regulation of synaptic vesicle exocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.
GO:2000303	regulation of ceramide biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
GO:2000304	positive regulation of ceramide biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.
GO:2000305	semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance	biological_process	Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance.
GO:2000306	positive regulation of photomorphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of photomorphogenesis.
GO:2000307	regulation of tumor necrosis factor (ligand) superfamily member 11 production	biological_process	Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
GO:2000308	negative regulation of tumor necrosis factor (ligand) superfamily member 11 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	biological_process	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
GO:2000310	regulation of NMDA receptor activity	biological_process	Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
GO:2000311	regulation of AMPA receptor activity	biological_process	Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
GO:2000312	regulation of kainate selective glutamate receptor activity	biological_process	Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.
GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
GO:2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
GO:2000315	positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	biological_process	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
GO:2000316	regulation of T-helper 17 type immune response	biological_process	Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.
GO:2000317	negative regulation of T-helper 17 type immune response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.
GO:2000318	positive regulation of T-helper 17 type immune response	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.
GO:2000319	regulation of T-helper 17 cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.
GO:2000320	negative regulation of T-helper 17 cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.
GO:2000321	positive regulation of T-helper 17 cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.
GO:2000322	regulation of glucocorticoid receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.
GO:2000324	positive regulation of glucocorticoid receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.
GO:2000328	regulation of T-helper 17 cell lineage commitment	biological_process	Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.
GO:2000329	negative regulation of T-helper 17 cell lineage commitment	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.
GO:2000330	positive regulation of T-helper 17 cell lineage commitment	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.
GO:2000331	regulation of terminal button organization	biological_process	Any process that modulates the frequency, rate or extent of terminal button organization.
GO:2000332	regulation of blood microparticle formation	biological_process	Any process that modulates the frequency, rate or extent of blood microparticle formation.
GO:2000333	negative regulation of blood microparticle formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.
GO:2000334	positive regulation of blood microparticle formation	biological_process	Any process that activates or increases the frequency, rate or extent of blood microparticle formation.
GO:2000335	regulation of endothelial microparticle formation	biological_process	Any process that modulates the frequency, rate or extent of endothelial microparticle formation.
GO:2000336	negative regulation of endothelial microparticle formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.
GO:2000337	positive regulation of endothelial microparticle formation	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.
GO:2000338	regulation of chemokine (C-X-C motif) ligand 1 production	biological_process	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
GO:2000339	negative regulation of chemokine (C-X-C motif) ligand 1 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	biological_process	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	biological_process	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	biological_process	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
GO:2000344	positive regulation of acrosome reaction	biological_process	Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
GO:2000345	regulation of hepatocyte proliferation	biological_process	Any process that modulates the frequency, rate or extent of hepatocyte proliferation.
GO:2000346	negative regulation of hepatocyte proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.
GO:2000347	positive regulation of hepatocyte proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
GO:2000348	regulation of CD40 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.
GO:2000349	negative regulation of CD40 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.
GO:2000350	positive regulation of CD40 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.
GO:2000351	regulation of endothelial cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.
GO:2000352	negative regulation of endothelial cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.
GO:2000353	positive regulation of endothelial cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.
GO:2000354	regulation of ovarian follicle development	biological_process	Any process that modulates the frequency, rate or extent of ovarian follicle development.
GO:2000355	negative regulation of ovarian follicle development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
GO:2000356	regulation of kidney smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.
GO:2000359	regulation of binding of sperm to zona pellucida	biological_process	Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.
GO:2000360	negative regulation of binding of sperm to zona pellucida	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
GO:2000361	regulation of prostaglandin-E synthase activity	biological_process	Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.
GO:2000362	negative regulation of prostaglandin-E synthase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.
GO:2000363	positive regulation of prostaglandin-E synthase activity	biological_process	Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.
GO:2000367	regulation of acrosomal vesicle exocytosis	biological_process	Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.
GO:2000368	positive regulation of acrosomal vesicle exocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
GO:2000369	regulation of clathrin-dependent endocytosis	biological_process	Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.
GO:2000370	positive regulation of clathrin-dependent endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
GO:2000371	regulation of DNA topoisomerase (ATP-hydrolyzing) activity	biological_process	Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
GO:2000372	negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	biological_process	Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
GO:2000374	regulation of oxygen metabolic process	biological_process	Any process that modulates the frequency, rate or extent of oxygen metabolic process.
GO:2000375	negative regulation of oxygen metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.
GO:2000376	positive regulation of oxygen metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.
GO:2000377	regulation of reactive oxygen species metabolic process	biological_process	Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
GO:2000378	negative regulation of reactive oxygen species metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
GO:2000379	positive regulation of reactive oxygen species metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
GO:2000380	regulation of mesoderm development	biological_process	Any process that modulates the frequency, rate or extent of mesoderm development.
GO:2000381	negative regulation of mesoderm development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.
GO:2000382	positive regulation of mesoderm development	biological_process	Any process that activates or increases the frequency, rate or extent of mesoderm development.
GO:2000383	regulation of ectoderm development	biological_process	Any process that modulates the frequency, rate or extent of ectoderm development.
GO:2000384	negative regulation of ectoderm development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.
GO:2000385	positive regulation of ectoderm development	biological_process	Any process that activates or increases the frequency, rate or extent of ectoderm development.
GO:2000386	positive regulation of ovarian follicle development	biological_process	Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
GO:2000387	regulation of antral ovarian follicle growth	biological_process	Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.
GO:2000388	positive regulation of antral ovarian follicle growth	biological_process	Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.
GO:2000389	regulation of neutrophil extravasation	biological_process	Any process that modulates the frequency, rate or extent of neutrophil extravasation.
GO:2000390	negative regulation of neutrophil extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation.
GO:2000391	positive regulation of neutrophil extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.
GO:2000392	regulation of lamellipodium morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis.
GO:2000393	negative regulation of lamellipodium morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.
GO:2000394	positive regulation of lamellipodium morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.
GO:2000395	regulation of ubiquitin-dependent endocytosis	biological_process	Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis.
GO:2000396	negative regulation of ubiquitin-dependent endocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis.
GO:2000397	positive regulation of ubiquitin-dependent endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.
GO:2000398	regulation of thymocyte aggregation	biological_process	Any process that modulates the frequency, rate or extent of thymocyte aggregation.
GO:2000399	negative regulation of thymocyte aggregation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation.
GO:2000400	positive regulation of thymocyte aggregation	biological_process	Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.
GO:2000401	regulation of lymphocyte migration	biological_process	Any process that modulates the frequency, rate or extent of lymphocyte migration.
GO:2000402	negative regulation of lymphocyte migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.
GO:2000403	positive regulation of lymphocyte migration	biological_process	Any process that activates or increases the frequency, rate or extent of lymphocyte migration.
GO:2000404	regulation of T cell migration	biological_process	Any process that modulates the frequency, rate or extent of T cell migration.
GO:2000405	negative regulation of T cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.
GO:2000406	positive regulation of T cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of T cell migration.
GO:2000407	regulation of T cell extravasation	biological_process	Any process that modulates the frequency, rate or extent of T cell extravasation.
GO:2000408	negative regulation of T cell extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation.
GO:2000409	positive regulation of T cell extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of T cell extravasation.
GO:2000410	regulation of thymocyte migration	biological_process	Any process that modulates the frequency, rate or extent of thymocyte migration.
GO:2000411	negative regulation of thymocyte migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.
GO:2000412	positive regulation of thymocyte migration	biological_process	Any process that activates or increases the frequency, rate or extent of thymocyte migration.
GO:2000413	regulation of fibronectin-dependent thymocyte migration	biological_process	Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration.
GO:2000414	negative regulation of fibronectin-dependent thymocyte migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.
GO:2000415	positive regulation of fibronectin-dependent thymocyte migration	biological_process	Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.
GO:2000416	regulation of eosinophil migration	biological_process	Any process that modulates the frequency, rate or extent of eosinophil migration.
GO:2000417	negative regulation of eosinophil migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.
GO:2000418	positive regulation of eosinophil migration	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil migration.
GO:2000419	regulation of eosinophil extravasation	biological_process	Any process that modulates the frequency, rate or extent of eosinophil extravasation.
GO:2000420	negative regulation of eosinophil extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.
GO:2000421	positive regulation of eosinophil extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.
GO:2000422	regulation of eosinophil chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.
GO:2000423	negative regulation of eosinophil chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.
GO:2000424	positive regulation of eosinophil chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.
GO:2000425	regulation of apoptotic cell clearance	biological_process	Any process that modulates the frequency, rate or extent of apoptotic cell clearance.
GO:2000426	negative regulation of apoptotic cell clearance	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.
GO:2000427	positive regulation of apoptotic cell clearance	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.
GO:2000428	regulation of neutrophil aggregation	biological_process	Any process that modulates the frequency, rate or extent of neutrophil aggregation.
GO:2000429	negative regulation of neutrophil aggregation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation.
GO:2000430	positive regulation of neutrophil aggregation	biological_process	Any process that activates or increases the frequency, rate or extent of neutrophil aggregation.
GO:2000431	regulation of cytokinesis, actomyosin contractile ring assembly	biological_process	Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
GO:2000432	negative regulation of cytokinesis, actomyosin contractile ring assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
GO:2000433	positive regulation of cytokinesis, actomyosin contractile ring assembly	biological_process	Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
GO:2000434	regulation of protein neddylation	biological_process	Any process that modulates the frequency, rate or extent of protein neddylation.
GO:2000435	negative regulation of protein neddylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation.
GO:2000436	positive regulation of protein neddylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein neddylation.
GO:2000437	regulation of monocyte extravasation	biological_process	Any process that modulates the frequency, rate or extent of monocyte extravasation.
GO:2000438	negative regulation of monocyte extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.
GO:2000439	positive regulation of monocyte extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of monocyte extravasation.
GO:2000440	regulation of toll-like receptor 15 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.
GO:2000441	negative regulation of toll-like receptor 15 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.
GO:2000442	positive regulation of toll-like receptor 15 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.
GO:2000443	regulation of toll-like receptor 21 signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.
GO:2000444	negative regulation of toll-like receptor 21 signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.
GO:2000445	positive regulation of toll-like receptor 21 signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.
GO:2000446	regulation of macrophage migration inhibitory factor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
GO:2000447	negative regulation of macrophage migration inhibitory factor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
GO:2000448	positive regulation of macrophage migration inhibitory factor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
GO:2000449	regulation of CD8-positive, alpha-beta T cell extravasation	biological_process	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
GO:2000450	negative regulation of CD8-positive, alpha-beta T cell extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
GO:2000451	positive regulation of CD8-positive, alpha-beta T cell extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
GO:2000452	regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	biological_process	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
GO:2000453	negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
GO:2000454	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
GO:2000455	regulation of T-helper 17 cell extravasation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.
GO:2000456	negative regulation of T-helper 17 cell extravasation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.
GO:2000457	positive regulation of T-helper 17 cell extravasation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation.
GO:2000458	regulation of astrocyte chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.
GO:2000459	negative regulation of astrocyte chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.
GO:2000463	positive regulation of excitatory postsynaptic potential	biological_process	Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
GO:2000464	positive regulation of astrocyte chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.
GO:2000465	regulation of glycogen (starch) synthase activity	biological_process	Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.
GO:2000466	negative regulation of glycogen (starch) synthase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.
GO:2000467	positive regulation of glycogen (starch) synthase activity	biological_process	Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.
GO:2000468	regulation of peroxidase activity	biological_process	Any process that modulates the frequency, rate or extent of peroxidase activity.
GO:2000469	negative regulation of peroxidase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity.
GO:2000470	positive regulation of peroxidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of peroxidase activity.
GO:2000471	regulation of hematopoietic stem cell migration	biological_process	Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.
GO:2000472	negative regulation of hematopoietic stem cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.
GO:2000473	positive regulation of hematopoietic stem cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.
GO:2000474	regulation of opioid receptor signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway.
GO:2000475	negative regulation of opioid receptor signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.
GO:2000476	positive regulation of opioid receptor signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.
GO:2000477	regulation of metanephric podocyte development	biological_process	Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.
GO:2000478	positive regulation of metanephric podocyte development	biological_process	Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.
GO:2000479	regulation of cAMP-dependent protein kinase activity	biological_process	Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.
GO:2000480	negative regulation of cAMP-dependent protein kinase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.
GO:2000485	regulation of glutamine transport	biological_process	Any process that modulates the frequency, rate or extent of glutamine transport.
GO:2000486	negative regulation of glutamine transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.
GO:2000487	positive regulation of glutamine transport	biological_process	Any process that activates or increases the frequency, rate or extent of glutamine transport.
GO:2000488	positive regulation of brassinosteroid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.
GO:2000489	regulation of hepatic stellate cell activation	biological_process	Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.
GO:2000490	negative regulation of hepatic stellate cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.
GO:2000491	positive regulation of hepatic stellate cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
GO:2000492	regulation of interleukin-18-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.
GO:2000493	negative regulation of interleukin-18-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.
GO:2000494	positive regulation of interleukin-18-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway.
GO:2000495	regulation of cell proliferation involved in compound eye morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
GO:2000496	negative regulation of cell proliferation involved in compound eye morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
GO:2000497	positive regulation of cell proliferation involved in compound eye morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
GO:2000501	regulation of natural killer cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.
GO:2000502	negative regulation of natural killer cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.
GO:2000503	positive regulation of natural killer cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.
GO:2000504	positive regulation of blood vessel remodeling	biological_process	Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.
GO:2000508	regulation of dendritic cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.
GO:2000509	negative regulation of dendritic cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.
GO:2000510	positive regulation of dendritic cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.
GO:2000511	regulation of granzyme A production	biological_process	Any process that modulates the frequency, rate or extent of granzyme A production.
GO:2000512	negative regulation of granzyme A production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.
GO:2000513	positive regulation of granzyme A production	biological_process	Any process that activates or increases the frequency, rate or extent of granzyme A production.
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	biological_process	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
GO:2000517	regulation of T-helper 1 cell activation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.
GO:2000518	negative regulation of T-helper 1 cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.
GO:2000519	positive regulation of T-helper 1 cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation.
GO:2000520	regulation of immunological synapse formation	biological_process	Any process that modulates the frequency, rate or extent of immunological synapse formation.
GO:2000521	negative regulation of immunological synapse formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.
GO:2000522	positive regulation of immunological synapse formation	biological_process	Any process that activates or increases the frequency, rate or extent of immunological synapse formation.
GO:2000523	regulation of T cell costimulation	biological_process	Any process that modulates the frequency, rate or extent of T cell costimulation.
GO:2000524	negative regulation of T cell costimulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.
GO:2000525	positive regulation of T cell costimulation	biological_process	Any process that activates or increases the frequency, rate or extent of T cell costimulation.
GO:2000526	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	biological_process	Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.
GO:2000527	regulation of myeloid dendritic cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.
GO:2000528	negative regulation of myeloid dendritic cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.
GO:2000529	positive regulation of myeloid dendritic cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.
GO:2000532	regulation of renal albumin absorption	biological_process	Any process that modulates the frequency, rate or extent of renal albumin absorption.
GO:2000533	negative regulation of renal albumin absorption	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.
GO:2000534	positive regulation of renal albumin absorption	biological_process	Any process that activates or increases the frequency, rate or extent of renal albumin absorption.
GO:2000535	regulation of entry of bacterium into host cell	biological_process	Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.
GO:2000536	negative regulation of entry of bacterium into host cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.
GO:2000537	regulation of B cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of B cell chemotaxis.
GO:2000538	positive regulation of B cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.
GO:2000539	regulation of protein geranylgeranylation	biological_process	Any process that modulates the frequency, rate or extent of protein geranylgeranylation.
GO:2000540	negative regulation of protein geranylgeranylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation.
GO:2000541	positive regulation of protein geranylgeranylation	biological_process	Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.
GO:2000542	negative regulation of gastrulation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.
GO:2000543	positive regulation of gastrulation	biological_process	Any process that activates or increases the frequency, rate or extent of gastrulation.
GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
GO:2000545	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
GO:2000546	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
GO:2000547	regulation of dendritic cell dendrite assembly	biological_process	Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.
GO:2000548	negative regulation of dendritic cell dendrite assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.
GO:2000549	positive regulation of dendritic cell dendrite assembly	biological_process	Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.
GO:2000550	negative regulation of B cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.
GO:2000551	regulation of T-helper 2 cell cytokine production	biological_process	Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.
GO:2000552	negative regulation of T-helper 2 cell cytokine production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.
GO:2000553	positive regulation of T-helper 2 cell cytokine production	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
GO:2000554	regulation of T-helper 1 cell cytokine production	biological_process	Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.
GO:2000555	negative regulation of T-helper 1 cell cytokine production	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.
GO:2000556	positive regulation of T-helper 1 cell cytokine production	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.
GO:2000557	regulation of immunoglobulin production in mucosal tissue	biological_process	Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue.
GO:2000558	positive regulation of immunoglobulin production in mucosal tissue	biological_process	Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue.
GO:2000559	regulation of CD24 production	biological_process	Any process that modulates the frequency, rate or extent of CD24 biosynthetic process.
GO:2000560	positive regulation of CD24 production	biological_process	Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process.
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
GO:2000565	negative regulation of CD8-positive, alpha-beta T cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
GO:2000567	regulation of memory T cell activation	biological_process	Any process that modulates the frequency, rate or extent of memory T cell activation.
GO:2000568	positive regulation of memory T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of memory T cell activation.
GO:2000569	regulation of T-helper 2 cell activation	biological_process	Any process that modulates the frequency, rate or extent of T-helper 2 cell activation.
GO:2000570	positive regulation of T-helper 2 cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.
GO:2000571	regulation of interleukin-4-dependent isotype switching to IgE isotypes	biological_process	Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.
GO:2000572	positive regulation of interleukin-4-dependent isotype switching to IgE isotypes	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.
GO:2000573	positive regulation of DNA biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
GO:2000584	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
GO:2000585	positive regulation of platelet-derived growth factor receptor-alpha signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
GO:2000589	regulation of metanephric mesenchymal cell migration	biological_process	Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.
GO:2000590	negative regulation of metanephric mesenchymal cell migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.
GO:2000591	positive regulation of metanephric mesenchymal cell migration	biological_process	Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.
GO:2000592	regulation of metanephric DCT cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation.
GO:2000593	negative regulation of metanephric DCT cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation.
GO:2000594	positive regulation of metanephric DCT cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.
GO:2000595	regulation of optic nerve formation	biological_process	Any process that modulates the frequency, rate or extent of optic nerve formation.
GO:2000596	negative regulation of optic nerve formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.
GO:2000597	positive regulation of optic nerve formation	biological_process	Any process that activates or increases the frequency, rate or extent of optic nerve formation.
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	biological_process	Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
GO:2000603	regulation of secondary growth	biological_process	Any process that modulates the frequency, rate or extent of secondary growth.
GO:2000604	negative regulation of secondary growth	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth.
GO:2000605	positive regulation of secondary growth	biological_process	Any process that activates or increases the frequency, rate or extent of secondary growth.
GO:2000606	regulation of cell proliferation involved in mesonephros development	biological_process	Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.
GO:2000608	positive regulation of cell proliferation involved in mesonephros development	biological_process	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.
GO:2000609	regulation of thyroid hormone generation	biological_process	Any process that modulates the frequency, rate or extent of thyroid hormone generation.
GO:2000610	negative regulation of thyroid hormone generation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.
GO:2000611	positive regulation of thyroid hormone generation	biological_process	Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.
GO:2000612	regulation of thyroid-stimulating hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.
GO:2000613	negative regulation of thyroid-stimulating hormone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.
GO:2000614	positive regulation of thyroid-stimulating hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.
GO:2000615	regulation of histone H3-K9 acetylation	biological_process	Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.
GO:2000616	negative regulation of histone H3-K9 acetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation.
GO:2000617	positive regulation of histone H3-K9 acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.
GO:2000620	positive regulation of histone H4-K16 acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.
GO:2000621	regulation of DNA replication termination	biological_process	Any process that modulates the frequency, rate or extent of DNA replication termination.
GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	biological_process	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
GO:2000624	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	biological_process	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
GO:2000625	regulation of miRNA catabolic process	biological_process	Any process that modulates the frequency, rate or extent of miRNA catabolic process.
GO:2000626	negative regulation of miRNA catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.
GO:2000627	positive regulation of miRNA catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.
GO:2000628	regulation of miRNA metabolic process	biological_process	Any process that modulates the frequency, rate or extent of miRNA metabolic process.
GO:2000629	negative regulation of miRNA metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.
GO:2000630	positive regulation of miRNA metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.
GO:2000631	regulation of pre-miRNA processing	biological_process	Any process that modulates the frequency, rate or extent of pre-microRNA processing.
GO:2000632	negative regulation of pre-miRNA processing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.
GO:2000633	positive regulation of pre-miRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.
GO:2000634	regulation of primary miRNA processing	biological_process	Any process that modulates the frequency, rate or extent of primary microRNA processing.
GO:2000635	negative regulation of primary miRNA processing	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.
GO:2000636	positive regulation of primary miRNA processing	biological_process	Any process that activates or increases the frequency, rate or extent of primary microRNA processing.
GO:2000637	positive regulation of miRNA-mediated gene silencing	biological_process	A process that activates or increases the frequency, rate or extent of gene silencing by a microRNA (miRNA).
GO:2000638	regulation of SREBP signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of the SREBP signaling pathway.
GO:2000639	negative regulation of SREBP signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.
GO:2000640	positive regulation of SREBP signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.
GO:2000641	regulation of early endosome to late endosome transport	biological_process	Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.
GO:2000642	negative regulation of early endosome to late endosome transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.
GO:2000643	positive regulation of early endosome to late endosome transport	biological_process	Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.
GO:2000644	regulation of receptor catabolic process	biological_process	Any process that modulates the frequency, rate or extent of receptor catabolic process.
GO:2000645	negative regulation of receptor catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.
GO:2000646	positive regulation of receptor catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of receptor catabolic process.
GO:2000647	negative regulation of stem cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.
GO:2000648	positive regulation of stem cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
GO:2000649	regulation of sodium ion transmembrane transporter activity	biological_process	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
GO:2000650	negative regulation of sodium ion transmembrane transporter activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	biological_process	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
GO:2000652	regulation of secondary cell wall biogenesis	biological_process	Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.
GO:2000654	regulation of cellular response to testosterone stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.
GO:2000655	negative regulation of cellular response to testosterone stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.
GO:2000656	regulation of apolipoprotein binding	biological_process	Any process that modulates the frequency, rate or extent of apolipoprotein binding.
GO:2000657	negative regulation of apolipoprotein binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.
GO:2000658	positive regulation of apolipoprotein binding	biological_process	Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.
GO:2000659	regulation of interleukin-1-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.
GO:2000661	positive regulation of interleukin-1-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.
GO:2000668	regulation of dendritic cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.
GO:2000669	negative regulation of dendritic cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.
GO:2000670	positive regulation of dendritic cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.
GO:2000671	regulation of motor neuron apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.
GO:2000672	negative regulation of motor neuron apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.
GO:2000673	positive regulation of motor neuron apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.
GO:2000674	regulation of type B pancreatic cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.
GO:2000675	negative regulation of type B pancreatic cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.
GO:2000676	positive regulation of type B pancreatic cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.
GO:2000677	regulation of transcription regulatory region DNA binding	biological_process	Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.
GO:2000678	negative regulation of transcription regulatory region DNA binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
GO:2000679	positive regulation of transcription regulatory region DNA binding	biological_process	Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
GO:2000683	regulation of cellular response to X-ray	biological_process	Any process that modulates the frequency, rate or extent of cellular response to X-ray.
GO:2000684	negative regulation of cellular response to X-ray	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.
GO:2000685	positive regulation of cellular response to X-ray	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.
GO:2000689	actomyosin contractile ring assembly actin filament organization	biological_process	An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.
GO:2000690	regulation of cardiac muscle cell myoblast differentiation	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
GO:2000692	negative regulation of seed maturation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.
GO:2000693	positive regulation of seed maturation	biological_process	Any process that activates or increases the frequency, rate or extent of seed maturation.
GO:2000694	regulation of phragmoplast microtubule organization	biological_process	Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
GO:2000697	negative regulation of epithelial cell differentiation involved in kidney development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development	biological_process	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
GO:2000699	fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	biological_process	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
GO:2000700	positive regulation of cardiac muscle cell myoblast differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
GO:2000701	glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	biological_process	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
GO:2000702	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
GO:2000704	positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
GO:2000705	regulation of dense core granule biogenesis	biological_process	Any process that modulates the frequency, rate or extent of dense core granule biogenesis.
GO:2000706	negative regulation of dense core granule biogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.
GO:2000707	positive regulation of dense core granule biogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.
GO:2000709	regulation of maintenance of meiotic sister chromatid cohesion, centromeric	biological_process	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
GO:2000710	negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
GO:2000711	positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric	biological_process	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
GO:2000712	regulation of maintenance of meiotic sister chromatid cohesion, arms	biological_process	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
GO:2000713	negative regulation of maintenance of meiotic sister chromatid cohesion, arms	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
GO:2000714	positive regulation of maintenance of meiotic sister chromatid cohesion, arms	biological_process	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
GO:2000715	regulation of maintenance of mitotic sister chromatid cohesion, arms	biological_process	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
GO:2000716	negative regulation of maintenance of mitotic sister chromatid cohesion, arms	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
GO:2000717	positive regulation of maintenance of mitotic sister chromatid cohesion, arms	biological_process	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
GO:2000718	regulation of maintenance of mitotic sister chromatid cohesion, centromeric	biological_process	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
GO:2000719	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
GO:2000720	positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	biological_process	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
GO:2000722	regulation of cardiac vascular smooth muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
GO:2000723	negative regulation of cardiac vascular smooth muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
GO:2000724	positive regulation of cardiac vascular smooth muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
GO:2000725	regulation of cardiac muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.
GO:2000726	negative regulation of cardiac muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.
GO:2000727	positive regulation of cardiac muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
GO:2000728	regulation of mRNA export from nucleus in response to heat stress	biological_process	Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.
GO:2000730	regulation of termination of RNA polymerase I transcription	biological_process	Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.
GO:2000731	negative regulation of termination of RNA polymerase I transcription	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.
GO:2000732	positive regulation of termination of RNA polymerase I transcription	biological_process	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.
GO:2000733	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
GO:2000735	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	biological_process	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
GO:2000736	regulation of stem cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of stem cell differentiation.
GO:2000737	negative regulation of stem cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
GO:2000738	positive regulation of stem cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of stem cell differentiation.
GO:2000739	regulation of mesenchymal stem cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.
GO:2000740	negative regulation of mesenchymal stem cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.
GO:2000741	positive regulation of mesenchymal stem cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.
GO:2000742	regulation of anterior head development	biological_process	Any process that modulates the frequency, rate or extent of anterior head development.
GO:2000743	negative regulation of anterior head development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.
GO:2000744	positive regulation of anterior head development	biological_process	Any process that activates or increases the frequency, rate or extent of anterior head development.
GO:2000746	regulation of defecation rhythm	biological_process	Any process that modulates the frequency, rate or extent of defecation rhythm.
GO:2000747	negative regulation of defecation rhythm	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.
GO:2000748	positive regulation of defecation rhythm	biological_process	Any process that activates or increases the frequency, rate or extent of defecation rhythm.
GO:2000749	positive regulation of rDNA heterochromatin formation	biological_process	Any process that activates or increases the frequency, rate or extent of rDNA heterochromatin formation.
GO:2000750	negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
GO:2000752	regulation of glucosylceramide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process.
GO:2000753	positive regulation of glucosylceramide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.
GO:2000754	regulation of sphingomyelin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process.
GO:2000755	positive regulation of sphingomyelin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.
GO:2000756	regulation of peptidyl-lysine acetylation	biological_process	Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation.
GO:2000757	negative regulation of peptidyl-lysine acetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.
GO:2000758	positive regulation of peptidyl-lysine acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation.
GO:2000759	regulation of N-terminal peptidyl-lysine acetylation	biological_process	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
GO:2000760	negative regulation of N-terminal peptidyl-lysine acetylation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	biological_process	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
GO:2000762	regulation of phenylpropanoid metabolic process	biological_process	Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.
GO:2000763	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process	biological_process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.
GO:2000764	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.
GO:2000765	regulation of cytoplasmic translation	biological_process	Any process that modulates the frequency, rate or extent of cytoplasmic translation.
GO:2000766	negative regulation of cytoplasmic translation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.
GO:2000767	positive regulation of cytoplasmic translation	biological_process	Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.
GO:2000769	regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process	Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
GO:2000770	negative regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
GO:2000771	positive regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
GO:2000772	regulation of cellular senescence	biological_process	Any process that modulates the frequency, rate or extent of cellular senescence.
GO:2000773	negative regulation of cellular senescence	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.
GO:2000774	positive regulation of cellular senescence	biological_process	Any process that activates or increases the frequency, rate or extent of cellular senescence.
GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	biological_process	Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.
GO:2000779	regulation of double-strand break repair	biological_process	Any process that modulates the frequency, rate or extent of double-strand break repair.
GO:2000780	negative regulation of double-strand break repair	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.
GO:2000781	positive regulation of double-strand break repair	biological_process	Any process that activates or increases the frequency, rate or extent of double-strand break repair.
GO:2000782	regulation of establishment of cell polarity regulating cell shape	biological_process	Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.
GO:2000783	negative regulation of establishment of cell polarity regulating cell shape	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape.
GO:2000784	positive regulation of establishment of cell polarity regulating cell shape	biological_process	Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.
GO:2000785	regulation of autophagosome assembly	biological_process	Any process that modulates the frequency, rate or extent of autophagosome assembly.
GO:2000786	positive regulation of autophagosome assembly	biological_process	Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
GO:2000787	regulation of venous endothelial cell fate commitment	biological_process	Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.
GO:2000788	negative regulation of venous endothelial cell fate commitment	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment.
GO:2000789	positive regulation of venous endothelial cell fate commitment	biological_process	Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.
GO:2000790	regulation of mesenchymal cell proliferation involved in lung development	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
GO:2000792	positive regulation of mesenchymal cell proliferation involved in lung development	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
GO:2000793	cell proliferation involved in heart valve development	biological_process	Any cell proliferation that is involved in heart valve development.
GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.
GO:2000796	Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment	biological_process	Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.
GO:2000797	regulation of amniotic stem cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.
GO:2000798	negative regulation of amniotic stem cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.
GO:2000799	positive regulation of amniotic stem cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation.
GO:2000800	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	biological_process	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
GO:2000801	negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
GO:2000802	positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	biological_process	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
GO:2000804	regulation of termination of RNA polymerase II transcription, poly(A)-coupled	biological_process	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
GO:2000805	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
GO:2000806	positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled	biological_process	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
GO:2000807	regulation of synaptic vesicle clustering	biological_process	Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.
GO:2000808	negative regulation of synaptic vesicle clustering	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.
GO:2000809	positive regulation of synaptic vesicle clustering	biological_process	Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.
GO:2000810	regulation of bicellular tight junction assembly	biological_process	Any process that modulates the frequency, rate or extent of tight junction assembly.
GO:2000811	negative regulation of anoikis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.
GO:2000812	regulation of barbed-end actin filament capping	biological_process	Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.
GO:2000813	negative regulation of barbed-end actin filament capping	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.
GO:2000814	positive regulation of barbed-end actin filament capping	biological_process	Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.
GO:2000815	regulation of mRNA stability involved in response to oxidative stress	biological_process	A process of regulation of mRNA stability that is involved in a response to oxidative stress.
GO:2000816	negative regulation of mitotic sister chromatid separation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.
GO:2000818	negative regulation of myoblast proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.
GO:2000819	regulation of nucleotide-excision repair	biological_process	Any process that modulates the frequency, rate or extent of nucleotide-excision repair.
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	biological_process	Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.
GO:2000821	regulation of grooming behavior	biological_process	Any process that modulates the frequency, rate or extent of grooming behavior.
GO:2000822	regulation of behavioral fear response	biological_process	Any process that modulates the frequency, rate or extent of behavioral fear response.
GO:2000825	positive regulation of androgen receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of androgen receptor activity.
GO:2000826	regulation of heart morphogenesis	biological_process	Any process that modulates the frequency, rate or extent of heart morphogenesis.
GO:2000827	mitochondrial RNA surveillance	biological_process	The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.
GO:2000828	regulation of parathyroid hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.
GO:2000829	negative regulation of parathyroid hormone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.
GO:2000830	positive regulation of parathyroid hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.
GO:2000831	regulation of steroid hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of steroid hormone secretion.
GO:2000832	negative regulation of steroid hormone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.
GO:2000833	positive regulation of steroid hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.
GO:2000834	regulation of androgen secretion	biological_process	Any process that modulates the frequency, rate or extent of androgen secretion.
GO:2000835	negative regulation of androgen secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.
GO:2000836	positive regulation of androgen secretion	biological_process	Any process that activates or increases the frequency, rate or extent of androgen secretion.
GO:2000837	regulation of androstenedione secretion	biological_process	Any process that modulates the frequency, rate or extent of androstenedione secretion.
GO:2000838	negative regulation of androstenedione secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.
GO:2000839	positive regulation of androstenedione secretion	biological_process	Any process that activates or increases the frequency, rate or extent of androstenedione secretion.
GO:2000840	regulation of dehydroepiandrosterone secretion	biological_process	Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.
GO:2000841	negative regulation of dehydroepiandrosterone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.
GO:2000842	positive regulation of dehydroepiandrosterone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion.
GO:2000843	regulation of testosterone secretion	biological_process	Any process that modulates the frequency, rate or extent of testosterone secretion.
GO:2000844	negative regulation of testosterone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.
GO:2000845	positive regulation of testosterone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of testosterone secretion.
GO:2000846	regulation of corticosteroid hormone secretion	biological_process	Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.
GO:2000847	negative regulation of corticosteroid hormone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.
GO:2000848	positive regulation of corticosteroid hormone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.
GO:2000849	regulation of glucocorticoid secretion	biological_process	Any process that modulates the frequency, rate or extent of glucocorticoid secretion.
GO:2000850	negative regulation of glucocorticoid secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.
GO:2000851	positive regulation of glucocorticoid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.
GO:2000852	regulation of corticosterone secretion	biological_process	Any process that modulates the frequency, rate or extent of corticosterone secretion.
GO:2000853	negative regulation of corticosterone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.
GO:2000854	positive regulation of corticosterone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of corticosterone secretion.
GO:2000855	regulation of mineralocorticoid secretion	biological_process	Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.
GO:2000856	negative regulation of mineralocorticoid secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.
GO:2000857	positive regulation of mineralocorticoid secretion	biological_process	Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.
GO:2000858	regulation of aldosterone secretion	biological_process	Any process that modulates the frequency, rate or extent of aldosterone secretion.
GO:2000859	negative regulation of aldosterone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.
GO:2000860	positive regulation of aldosterone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of aldosterone secretion.
GO:2000861	regulation of estrogen secretion	biological_process	Any process that modulates the frequency, rate or extent of estrogen secretion.
GO:2000862	negative regulation of estrogen secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.
GO:2000863	positive regulation of estrogen secretion	biological_process	Any process that activates or increases the frequency, rate or extent of estrogen secretion.
GO:2000864	regulation of estradiol secretion	biological_process	Any process that modulates the frequency, rate or extent of estradiol secretion.
GO:2000865	negative regulation of estradiol secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.
GO:2000866	positive regulation of estradiol secretion	biological_process	Any process that activates or increases the frequency, rate or extent of estradiol secretion.
GO:2000867	regulation of estrone secretion	biological_process	Any process that modulates the frequency, rate or extent of estrone secretion.
GO:2000868	negative regulation of estrone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.
GO:2000869	positive regulation of estrone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of estrone secretion.
GO:2000870	regulation of progesterone secretion	biological_process	Any process that modulates the frequency, rate or extent of progesterone secretion.
GO:2000871	negative regulation of progesterone secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.
GO:2000872	positive regulation of progesterone secretion	biological_process	Any process that activates or increases the frequency, rate or extent of progesterone secretion.
GO:2000874	regulation of glyoxylate cycle	biological_process	Any process that modulates the frequency, rate or extent of glyoxylate cycle.
GO:2000875	negative regulation of glyoxylate cycle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle.
GO:2000876	positive regulation of glyoxylate cycle	biological_process	Any process that activates or increases the frequency, rate or extent of glyoxylate cycle.
GO:2000877	negative regulation of oligopeptide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.
GO:2000878	positive regulation of oligopeptide transport	biological_process	Any process that activates or increases the frequency, rate or extent of oligopeptide transport.
GO:2000879	negative regulation of dipeptide transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.
GO:2000880	positive regulation of dipeptide transport	biological_process	Any process that activates or increases the frequency, rate or extent of dipeptide transport.
GO:2000881	regulation of starch catabolic process	biological_process	Any process that modulates the frequency, rate or extent of starch catabolic process.
GO:2000882	negative regulation of starch catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.
GO:2000883	positive regulation of starch catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of starch catabolic process.
GO:2000884	glucomannan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a glucomannan.
GO:2000885	galactoglucomannan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan.
GO:2000886	glucuronoxylan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan.
GO:2000887	glucuronoarabinoxylan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.
GO:2000888	arabinoxylan-containing compound catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.
GO:2000889	cellodextrin metabolic process	biological_process	The chemical reactions and pathways involving a cellodextrin.
GO:2000890	cellodextrin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cellodextrin.
GO:2000891	cellobiose metabolic process	biological_process	The chemical reactions and pathways involving a cellobiose.
GO:2000892	cellobiose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cellobiose.
GO:2000893	cellotriose metabolic process	biological_process	The chemical reactions and pathways involving a cellotriose.
GO:2000894	cellotriose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cellotriose.
GO:2000895	hemicellulose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a hemicellulose.
GO:2000896	amylopectin metabolic process	biological_process	The chemical reactions and pathways involving an amylopectin.
GO:2000897	amylopectin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of an amylopectin.
GO:2000898	regulation of glucomannan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of glucomannan catabolic process.
GO:2000899	xyloglucan catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a xyloglucan.
GO:2000900	cyclodextrin metabolic process	biological_process	The chemical reactions and pathways involving a cyclodextrin.
GO:2000901	cyclodextrin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.
GO:2000902	cellooligosaccharide metabolic process	biological_process	The chemical reactions and pathways involving a cellooligosaccharide.
GO:2000903	cellooligosaccharide catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.
GO:2000904	regulation of starch metabolic process	biological_process	Any process that modulates the frequency, rate or extent of starch metabolic process.
GO:2000905	negative regulation of starch metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.
GO:2000906	positive regulation of starch metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of starch metabolic process.
GO:2000907	negative regulation of glucomannan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.
GO:2000908	positive regulation of glucomannan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.
GO:2000909	regulation of sterol import	biological_process	Any process that modulates the frequency, rate or extent of sterol import.
GO:2000910	negative regulation of sterol import	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of sterol import.
GO:2000911	positive regulation of sterol import	biological_process	Any process that activates or increases the frequency, rate or extent of sterol import.
GO:2000912	regulation of galactoglucomannan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.
GO:2000913	negative regulation of galactoglucomannan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.
GO:2000914	positive regulation of galactoglucomannan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.
GO:2000915	regulation of glucuronoxylan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.
GO:2000916	negative regulation of glucuronoxylan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process.
GO:2000917	positive regulation of glucuronoxylan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.
GO:2000918	regulation of glucuronoarabinoxylan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
GO:2000919	negative regulation of glucuronoarabinoxylan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
GO:2000920	positive regulation of glucuronoarabinoxylan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
GO:2000921	regulation of arabinoxylan-containing compound catabolic process	biological_process	Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
GO:2000922	negative regulation of arabinoxylan-containing compound catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
GO:2000923	positive regulation of arabinoxylan-containing compound catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
GO:2000924	regulation of cellodextrin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellodextrin metabolic process.
GO:2000925	negative regulation of cellodextrin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.
GO:2000926	positive regulation of cellodextrin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process.
GO:2000927	regulation of cellodextrin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.
GO:2000928	negative regulation of cellodextrin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.
GO:2000929	positive regulation of cellodextrin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.
GO:2000930	regulation of cellobiose metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellobiose metabolic process.
GO:2000931	negative regulation of cellobiose metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process.
GO:2000932	positive regulation of cellobiose metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process.
GO:2000933	regulation of cellotriose metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellotriose metabolic process.
GO:2000934	negative regulation of cellotriose metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.
GO:2000935	positive regulation of cellotriose metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.
GO:2000936	regulation of cellotriose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellotriose catabolic process.
GO:2000937	negative regulation of cellotriose catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process.
GO:2000938	positive regulation of cellotriose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.
GO:2000939	regulation of plant-type cell wall cellulose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
GO:2000940	negative regulation of plant-type cell wall cellulose catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
GO:2000941	positive regulation of plant-type cell wall cellulose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
GO:2000942	regulation of amylopectin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of amylopectin metabolic process.
GO:2000943	negative regulation of amylopectin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process.
GO:2000944	positive regulation of amylopectin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process.
GO:2000945	regulation of amylopectin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of amylopectin catabolic process.
GO:2000946	negative regulation of amylopectin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.
GO:2000947	positive regulation of amylopectin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.
GO:2000948	regulation of xyloglucan metabolic process	biological_process	Any process that modulates the frequency, rate or extent of xyloglucan metabolic process.
GO:2000949	negative regulation of xyloglucan metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process.
GO:2000950	positive regulation of xyloglucan metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process.
GO:2000951	regulation of xyloglucan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of xyloglucan catabolic process.
GO:2000952	negative regulation of xyloglucan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process.
GO:2000953	positive regulation of xyloglucan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process.
GO:2000954	regulation of cyclodextrin metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process.
GO:2000955	negative regulation of cyclodextrin metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process.
GO:2000956	positive regulation of cyclodextrin metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.
GO:2000957	regulation of cyclodextrin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process.
GO:2000958	negative regulation of cyclodextrin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process.
GO:2000959	positive regulation of cyclodextrin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.
GO:2000960	regulation of cellooligosaccharide metabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process.
GO:2000961	negative regulation of cellooligosaccharide metabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process.
GO:2000962	positive regulation of cellooligosaccharide metabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process.
GO:2000963	regulation of cellooligosaccharide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process.
GO:2000964	negative regulation of cellooligosaccharide catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process.
GO:2000965	positive regulation of cellooligosaccharide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.
GO:2000966	regulation of cell wall polysaccharide catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process.
GO:2000967	negative regulation of cell wall polysaccharide catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.
GO:2000968	positive regulation of cell wall polysaccharide catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.
GO:2000969	positive regulation of AMPA receptor activity	biological_process	Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.
GO:2000970	regulation of detection of glucose	biological_process	Any process that modulates the frequency, rate or extent of detection of glucose.
GO:2000971	negative regulation of detection of glucose	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose.
GO:2000972	positive regulation of detection of glucose	biological_process	Any process that activates or increases the frequency, rate or extent of detection of glucose.
GO:2000973	regulation of pro-B cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of pro-B cell differentiation.
GO:2000974	negative regulation of pro-B cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.
GO:2000975	positive regulation of pro-B cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.
GO:2000977	regulation of forebrain neuron differentiation	biological_process	Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.
GO:2000978	negative regulation of forebrain neuron differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.
GO:2000979	positive regulation of forebrain neuron differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.
GO:2000980	regulation of inner ear receptor cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.
GO:2000981	negative regulation of inner ear receptor cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.
GO:2000982	positive regulation of inner ear receptor cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.
GO:2000983	regulation of ATP citrate synthase activity	biological_process	Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.
GO:2000984	negative regulation of ATP citrate synthase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.
GO:2000985	positive regulation of ATP citrate synthase activity	biological_process	Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity.
GO:2000986	negative regulation of behavioral fear response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.
GO:2000987	positive regulation of behavioral fear response	biological_process	Any process that activates or increases the frequency, rate or extent of behavioral fear response.
GO:2000988	regulation of hemicellulose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.
GO:2000989	negative regulation of hemicellulose catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process.
GO:2000990	positive regulation of hemicellulose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.
GO:2000991	regulation of galactomannan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of galactomannan catabolic process.
GO:2000992	negative regulation of galactomannan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.
GO:2000993	positive regulation of galactomannan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.
GO:2000994	regulation of mannan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of mannan catabolic process.
GO:2000995	negative regulation of mannan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.
GO:2000996	positive regulation of mannan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of mannan catabolic process.
GO:2000997	regulation of cellulose catabolic process	biological_process	Any process that modulates the frequency, rate or extent of cellulose catabolic process.
GO:2000998	negative regulation of cellulose catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.
GO:2000999	positive regulation of cellulose catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.
GO:2001000	regulation of xylan catabolic process	biological_process	Any process that modulates the frequency, rate or extent of xylan catabolic process.
GO:2001001	negative regulation of xylan catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.
GO:2001002	positive regulation of xylan catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of xylan catabolic process.
GO:2001003	regulation of pectin catabolic process	biological_process	Any process that modulates the frequency, rate or extent of pectin catabolic process.
GO:2001004	negative regulation of pectin catabolic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.
GO:2001005	positive regulation of pectin catabolic process	biological_process	Any process that activates or increases the frequency, rate or extent of pectin catabolic process.
GO:2001006	regulation of cellulose biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.
GO:2001007	negative regulation of cellulose biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.
GO:2001008	positive regulation of cellulose biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.
GO:2001009	regulation of plant-type cell wall cellulose biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
GO:2001010	negative regulation of plant-type cell wall cellulose biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
GO:2001011	positive regulation of plant-type cell wall cellulose biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
GO:2001012	mesenchymal cell differentiation involved in renal system development	biological_process	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.
GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis	biological_process	Any epithelial cell proliferation that is involved in renal tubule morphogenesis.
GO:2001014	regulation of skeletal muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.
GO:2001015	negative regulation of skeletal muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.
GO:2001016	positive regulation of skeletal muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
GO:2001017	regulation of retrograde axon cargo transport	biological_process	Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.
GO:2001018	negative regulation of retrograde axon cargo transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.
GO:2001019	positive regulation of retrograde axon cargo transport	biological_process	Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.
GO:2001023	regulation of response to drug	biological_process	Any process that modulates the frequency, rate or extent of response to drug.
GO:2001024	negative regulation of response to drug	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to drug.
GO:2001025	positive regulation of response to drug	biological_process	Any process that activates or increases the frequency, rate or extent of response to drug.
GO:2001026	regulation of endothelial cell chemotaxis	biological_process	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.
GO:2001027	negative regulation of endothelial cell chemotaxis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.
GO:2001028	positive regulation of endothelial cell chemotaxis	biological_process	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
GO:2001029	regulation of cellular glucuronidation	biological_process	Any process that modulates the frequency, rate or extent of cellular glucuronidation.
GO:2001030	negative regulation of cellular glucuronidation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation.
GO:2001031	positive regulation of cellular glucuronidation	biological_process	Any process that activates or increases the frequency, rate or extent of cellular glucuronidation.
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	biological_process	Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	biological_process	Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
GO:2001035	regulation of tongue muscle cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.
GO:2001036	negative regulation of tongue muscle cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.
GO:2001037	positive regulation of tongue muscle cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.
GO:2001038	regulation of cellular response to drug	biological_process	Any process that modulates the frequency, rate or extent of cellular response to drug.
GO:2001039	negative regulation of cellular response to drug	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug.
GO:2001040	positive regulation of cellular response to drug	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to drug.
GO:2001042	negative regulation of septum digestion after cytokinesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
GO:2001043	positive regulation of septum digestion after cytokinesis	biological_process	Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
GO:2001044	regulation of integrin-mediated signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.
GO:2001045	negative regulation of integrin-mediated signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.
GO:2001046	positive regulation of integrin-mediated signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
GO:2001049	regulation of tendon cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of tendon cell differentiation.
GO:2001050	negative regulation of tendon cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.
GO:2001051	positive regulation of tendon cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.
GO:2001053	regulation of mesenchymal cell apoptotic process	biological_process	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.
GO:2001054	negative regulation of mesenchymal cell apoptotic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.
GO:2001055	positive regulation of mesenchymal cell apoptotic process	biological_process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.
GO:2001056	positive regulation of cysteine-type endopeptidase activity	biological_process	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.
GO:2001057	reactive nitrogen species metabolic process	biological_process	The chemical reactions and pathways involving a reactive nitrogen species.
GO:2001058	D-tagatose 6-phosphate metabolic process	biological_process	The chemical reactions and pathways involving a D-tagatose 6-phosphate.
GO:2001059	D-tagatose 6-phosphate catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.
GO:2001060	D-glycero-D-manno-heptose 7-phosphate metabolic process	biological_process	The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.
GO:2001061	D-glycero-D-manno-heptose 7-phosphate biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate.
GO:2001062	xylan binding	molecular_function	Binding to xylan.
GO:2001063	glucomannan binding	molecular_function	Binding to glucomannan.
GO:2001064	cellooligosaccharide binding	molecular_function	Binding to cellooligosaccharide.
GO:2001065	mannan binding	molecular_function	Binding to mannan.
GO:2001066	amylopectin binding	molecular_function	Binding to amylopectin.
GO:2001067	pullulan binding	molecular_function	Binding to pullulan.
GO:2001068	arabinoxylan binding	molecular_function	Binding to arabinoxylan.
GO:2001069	glycogen binding	molecular_function	Binding to glycogen.
GO:2001070	starch binding	molecular_function	Binding to starch.
GO:2001071	maltoheptaose binding	molecular_function	Binding to maltoheptaose.
GO:2001072	galactomannan binding	molecular_function	Binding to galactomannan.
GO:2001073	cyclodextrin binding	molecular_function	Binding to cyclodextrin.
GO:2001074	regulation of metanephric ureteric bud development	biological_process	Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.
GO:2001075	negative regulation of metanephric ureteric bud development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.
GO:2001076	positive regulation of metanephric ureteric bud development	biological_process	Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.
GO:2001077	(1->3),(1->4)-beta-glucan binding	molecular_function	Binding to (1->3),(1->4)-beta-glucan.
GO:2001078	(1->6)-beta-D-glucan binding	molecular_function	Binding to (1->6)-beta-D-glucan.
GO:2001079	beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding	molecular_function	Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.
GO:2001080	chitosan binding	molecular_function	Binding to chitosan.
GO:2001081	(1->4)-beta-D-galactan binding	molecular_function	Binding to (1->4)-beta-D-galactan.
GO:2001082	inulin binding	molecular_function	Binding to inulin.
GO:2001083	alpha-D-glucan binding	molecular_function	Binding to alpha-D-glucan.
GO:2001084	L-arabinofuranose binding	molecular_function	Binding to L-arabinofuranose.
GO:2001085	arabinogalactan binding	molecular_function	Binding to arabinogalactan.
GO:2001087	sophorose transport	biological_process	The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001088	trisaccharide transport	biological_process	The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001089	maltotriose transport	biological_process	The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001090	maltotriulose transport	biological_process	The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001091	nigerotriose transport	biological_process	The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001092	arabinotriose transport	biological_process	The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001093	galactotriose transport	biological_process	The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001094	xylotriose transport	biological_process	The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001095	mannotriose transport	biological_process	The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001096	cellotriose transport	biological_process	The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001097	laminaritriose transport	biological_process	The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001098	tetrasaccharide transport	biological_process	The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001099	maltotetraose transport	biological_process	The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001100	pentasaccharide transport	biological_process	The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001101	maltopentaose transport	biological_process	The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001102	hexasaccharide transport	biological_process	The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001103	maltohexaose transport	biological_process	The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001104	heptasaccharide transport	biological_process	The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001105	maltoheptaose transport	biological_process	The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity	biological_process	Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
GO:2001107	negative regulation of Rho guanyl-nucleotide exchange factor activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
GO:2001108	positive regulation of Rho guanyl-nucleotide exchange factor activity	biological_process	Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
GO:2001109	regulation of lens epithelial cell proliferation	biological_process	Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.
GO:2001110	negative regulation of lens epithelial cell proliferation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.
GO:2001111	positive regulation of lens epithelial cell proliferation	biological_process	Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.
GO:2001112	regulation of cellular response to hepatocyte growth factor stimulus	biological_process	Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
GO:2001113	negative regulation of cellular response to hepatocyte growth factor stimulus	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
GO:2001114	positive regulation of cellular response to hepatocyte growth factor stimulus	biological_process	Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
GO:2001115	methanopterin-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a methanopterin.
GO:2001116	methanopterin-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a methanopterin.
GO:2001117	tetrahydromethanopterin metabolic process	biological_process	The chemical reactions and pathways involving a tetrahydromethanopterin.
GO:2001118	tetrahydromethanopterin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.
GO:2001119	methanofuran metabolic process	biological_process	The chemical reactions and pathways involving a methanofuran.
GO:2001120	methanofuran biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a methanofuran.
GO:2001121	coenzyme gamma-F420-2 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.
GO:2001122	maltoheptaose metabolic process	biological_process	The chemical reactions and pathways involving a maltoheptaose.
GO:2001123	maltoheptaose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.
GO:2001124	regulation of translational frameshifting	biological_process	Any process that modulates the frequency, rate or extent of translational frameshifting.
GO:2001125	negative regulation of translational frameshifting	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.
GO:2001126	positive regulation of translational frameshifting	biological_process	Any process that activates or increases the frequency, rate or extent of translational frameshifting.
GO:2001127	methane biosynthetic process from formic acid	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a formic acid.
GO:2001128	methane biosynthetic process from methylamine	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a methylamine.
GO:2001129	methane biosynthetic process from dimethylamine	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine.
GO:2001130	methane biosynthetic process from trimethylamine	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine.
GO:2001131	methane biosynthetic process from dimethyl sulfide	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide.
GO:2001132	methane biosynthetic process from 3-(methylthio)propionic acid	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid.
GO:2001133	methane biosynthetic process from methanethiol	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a methanethiol.
GO:2001134	methane biosynthetic process from carbon monoxide	biological_process	The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide.
GO:2001135	regulation of endocytic recycling	biological_process	Any process that modulates the frequency, rate or extent of endocytic recycling.
GO:2001136	negative regulation of endocytic recycling	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling.
GO:2001137	positive regulation of endocytic recycling	biological_process	Any process that activates or increases the frequency, rate or extent of endocytic recycling.
GO:2001138	regulation of phospholipid transport	biological_process	Any process that modulates the frequency, rate or extent of phospholipid transport.
GO:2001139	negative regulation of phospholipid transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.
GO:2001140	positive regulation of phospholipid transport	biological_process	Any process that activates or increases the frequency, rate or extent of phospholipid transport.
GO:2001141	regulation of RNA biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
GO:2001142	nicotinate transport	biological_process	The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001143	N-methylnicotinate transport	biological_process	The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:2001144	regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
GO:2001145	negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
GO:2001146	positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
GO:2001147	camalexin binding	molecular_function	Binding to camalexin.
GO:2001148	regulation of dipeptide transmembrane transport	biological_process	Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport.
GO:2001149	negative regulation of dipeptide transmembrane transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport.
GO:2001150	positive regulation of dipeptide transmembrane transport	biological_process	Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
GO:2001151	regulation of renal water transport	biological_process	Any process that modulates the frequency, rate or extent of renal water transport.
GO:2001152	negative regulation of renal water transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.
GO:2001153	positive regulation of renal water transport	biological_process	Any process that activates or increases the frequency, rate or extent of renal water transport.
GO:2001154	regulation of glycolytic fermentation to ethanol	biological_process	Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.
GO:2001155	negative regulation of glycolytic fermentation to ethanol	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.
GO:2001156	regulation of proline catabolic process to glutamate	biological_process	Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate.
GO:2001157	negative regulation of proline catabolic process to glutamate	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate.
GO:2001158	positive regulation of proline catabolic process to glutamate	biological_process	Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate.
GO:2001159	regulation of protein localization by the Cvt pathway	biological_process	Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.
GO:2001166	regulation of histone H2B ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of histone H2B ubiquitination.
GO:2001168	positive regulation of histone H2B ubiquitination	biological_process	Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination.
GO:2001169	regulation of ATP biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of ATP biosynthetic process.
GO:2001170	negative regulation of ATP biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.
GO:2001171	positive regulation of ATP biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
GO:2001172	positive regulation of glycolytic fermentation to ethanol	biological_process	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.
GO:2001173	regulation of histone H2B conserved C-terminal lysine ubiquitination	biological_process	Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
GO:2001176	regulation of mediator complex assembly	biological_process	Any process that modulates the frequency, rate or extent of mediator complex assembly.
GO:2001177	negative regulation of mediator complex assembly	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.
GO:2001178	positive regulation of mediator complex assembly	biological_process	Any process that activates or increases the frequency, rate or extent of mediator complex assembly.
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	biological_process	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
GO:2001186	negative regulation of CD8-positive, alpha-beta T cell activation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation	biological_process	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
GO:2001188	regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological_process	Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	biological_process	Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
GO:2001191	regulation of gamma-delta T cell activation involved in immune response	biological_process	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
GO:2001192	negative regulation of gamma-delta T cell activation involved in immune response	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
GO:2001193	positive regulation of gamma-delta T cell activation involved in immune response	biological_process	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
GO:2001194	regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	biological_process	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
GO:2001195	negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
GO:2001196	positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	biological_process	Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
GO:2001197	basement membrane assembly involved in embryonic body morphogenesis	biological_process	Any basement membrane assembly that is involved in embryonic body morphogenesis.
GO:2001198	regulation of dendritic cell differentiation	biological_process	Any process that modulates the frequency, rate or extent of dendritic cell differentiation.
GO:2001199	negative regulation of dendritic cell differentiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.
GO:2001200	positive regulation of dendritic cell differentiation	biological_process	Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.
GO:2001204	regulation of osteoclast development	biological_process	Any process that modulates the frequency, rate or extent of osteoclast development.
GO:2001205	negative regulation of osteoclast development	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.
GO:2001206	positive regulation of osteoclast development	biological_process	Any process that activates or increases the frequency, rate or extent of osteoclast development.
GO:2001207	regulation of transcription elongation by RNA polymerase I	biological_process	Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
GO:2001208	negative regulation of transcription elongation by RNA polymerase I	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.
GO:2001209	positive regulation of transcription elongation by RNA polymerase I	biological_process	Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
GO:2001210	regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	biological_process	Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
GO:2001211	negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
GO:2001212	regulation of vasculogenesis	biological_process	Any process that modulates the frequency, rate or extent of vasculogenesis.
GO:2001213	negative regulation of vasculogenesis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.
GO:2001214	positive regulation of vasculogenesis	biological_process	Any process that activates or increases the frequency, rate or extent of vasculogenesis.
GO:2001222	regulation of neuron migration	biological_process	Any process that modulates the frequency, rate or extent of neuron migration.
GO:2001223	negative regulation of neuron migration	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.
GO:2001224	positive regulation of neuron migration	biological_process	Any process that activates or increases the frequency, rate or extent of neuron migration.
GO:2001225	regulation of chloride transport	biological_process	Any process that modulates the frequency, rate or extent of chloride transport.
GO:2001226	negative regulation of chloride transport	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.
GO:2001227	quercitrin binding	molecular_function	Binding to quercitrin.
GO:2001228	regulation of response to gamma radiation	biological_process	Any process that modulates the frequency, rate or extent of response to gamma radiation.
GO:2001229	negative regulation of response to gamma radiation	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.
GO:2001230	positive regulation of response to gamma radiation	biological_process	Any process that activates or increases the frequency, rate or extent of response to gamma radiation.
GO:2001231	regulation of protein localization to prospore membrane	biological_process	Any process that modulates the frequency, rate or extent of protein localization to prospore membrane.
GO:2001232	positive regulation of protein localization to prospore membrane	biological_process	Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane.
GO:2001233	regulation of apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.
GO:2001234	negative regulation of apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.
GO:2001235	positive regulation of apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
GO:2001236	regulation of extrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	biological_process	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	biological_process	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
GO:2001242	regulation of intrinsic apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
GO:2001245	regulation of phosphatidylcholine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process.
GO:2001246	negative regulation of phosphatidylcholine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.
GO:2001247	positive regulation of phosphatidylcholine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.
GO:2001248	regulation of ammonia assimilation cycle	biological_process	Any process that modulates the frequency, rate or extent of ammonia assimilation cycle.
GO:2001249	negative regulation of ammonia assimilation cycle	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle.
GO:2001250	positive regulation of ammonia assimilation cycle	biological_process	Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.
GO:2001251	negative regulation of chromosome organization	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.
GO:2001252	positive regulation of chromosome organization	biological_process	Any process that activates or increases the frequency, rate or extent of chromosome organization.
GO:2001256	regulation of store-operated calcium entry	biological_process	Any process that modulates the frequency, rate or extent of store-operated calcium entry.
GO:2001257	regulation of cation channel activity	biological_process	Any process that modulates the frequency, rate or extent of cation channel activity.
GO:2001258	negative regulation of cation channel activity	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity.
GO:2001259	positive regulation of cation channel activity	biological_process	Any process that activates or increases the frequency, rate or extent of cation channel activity.
GO:2001260	regulation of semaphorin-plexin signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway.
GO:2001261	negative regulation of semaphorin-plexin signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.
GO:2001262	positive regulation of semaphorin-plexin signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.
GO:2001263	regulation of C-C chemokine binding	biological_process	Any process that modulates the frequency, rate or extent of C-C chemokine binding.
GO:2001264	negative regulation of C-C chemokine binding	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.
GO:2001265	positive regulation of C-C chemokine binding	biological_process	Any process that activates or increases the frequency, rate or extent of C-C chemokine binding.
GO:2001266	Roundabout signaling pathway involved in axon guidance	biological_process	Any Roundabout signaling pathway that is involved in axon guidance.
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	biological_process	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	biological_process	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	biological_process	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	biological_process	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
GO:2001276	regulation of leucine biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of leucine biosynthetic process.
GO:2001277	negative regulation of leucine biosynthetic process	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process.
GO:2001278	positive regulation of leucine biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process.
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	biological_process	Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process.
GO:2001280	positive regulation of unsaturated fatty acid biosynthetic process	biological_process	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.
GO:2001281	regulation of muscle cell chemotaxis toward tendon cell	biological_process	Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.
GO:2001282	negative regulation of muscle cell chemotaxis toward tendon cell	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.
GO:2001283	Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell	biological_process	Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.
GO:2001284	regulation of BMP secretion	biological_process	Any process that modulates the frequency, rate or extent of BMP secretion.
GO:2001285	negative regulation of BMP secretion	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.
GO:2001286	regulation of caveolin-mediated endocytosis	biological_process	Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.
GO:2001287	negative regulation of caveolin-mediated endocytosis	biological_process	Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.
GO:2001288	positive regulation of caveolin-mediated endocytosis	biological_process	Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.
GO:2001289	lipid X metabolic process	biological_process	The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.
GO:2001290	hydroperoxide metabolic process	biological_process	The chemical reactions and pathways involving a hydroperoxide.
GO:2001291	codeine metabolic process	biological_process	The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.
GO:2001292	codeine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.
GO:2001293	malonyl-CoA metabolic process	biological_process	The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.
GO:2001294	malonyl-CoA catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A.
GO:2001295	malonyl-CoA biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.
GO:2001296	N(omega)-methyl-L-arginine metabolic process	biological_process	The chemical reactions and pathways involving N(omega)-methyl-L-arginine.
GO:2001297	N(omega)-methyl-L-arginine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.
GO:2001298	N(omega),N(omega)-dimethyl-L-arginine metabolic process	biological_process	The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.
GO:2001299	N(omega),N(omega)-dimethyl-L-arginine catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.
GO:2001300	lipoxin metabolic process	biological_process	The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid.
GO:2001301	lipoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid.
GO:2001302	lipoxin A4 metabolic process	biological_process	The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
GO:2001303	lipoxin A4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
GO:2001304	lipoxin B4 metabolic process	biological_process	The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
GO:2001305	xanthone-containing compound metabolic process	biological_process	The chemical reactions and pathways involving a xanthone-containing compound.
GO:2001306	lipoxin B4 biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
GO:2001307	xanthone-containing compound biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a xanthone-containing compound.
GO:2001308	gliotoxin metabolic process	biological_process	The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
GO:2001309	gliotoxin catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
GO:2001310	gliotoxin biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
GO:2001311	lysobisphosphatidic acid metabolic process	biological_process	The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.
GO:2001312	lysobisphosphatidic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.
GO:2001313	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process	biological_process	The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
GO:2001314	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process	biological_process	The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
GO:2001315	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
GO:2001316	kojic acid metabolic process	biological_process	The chemical reactions and pathways involving kojic acid.
GO:2001317	kojic acid biosynthetic process	biological_process	The chemical reactions and pathways resulting in the formation of kojic acid.